Catherine E. Costello, PhD
William Fairfield Warren Distinguished Professor
Boston University School of Medicine
Dept of Biochemistry

PhD, Georgetown University
MS, Georgetown University




Catherine Costello came to Boston University in 1994. That year she established the Center for Biomedical Mass Spectrometry, which has become an internationally recognized research center. She holds her primary appointment in the MED Biochemistry Department, with secondary appointments in the Department of Physiology & Biophysics and the Department of Chemistry. Her research, which focuses on determining the structures and functions of biologically important polymers, has revolutionized an important area of biochemistry by providing insights into the structures of molecules responsible for human disease. She is the author or co-author of more than 300 scientific papers, serves on a number of editorial boards of major journals, and has received numerous awards and honors, including the 2010 Field and Franklin Award from the American Chemical Society, one of the highest honors in her field.

Research Professor
Boston University School of Medicine
Physiology & Biophysics


Director
Boston University School of Medicine
Center for Biomedical Mass Spectrometry


Member
Boston University
BU-BMC Cancer Center


Member
Boston University
Amyloidosis Center


Member
Boston University
Evans Center for Interdisciplinary Biomedical Research


Member
Boston University
Genome Science Institute


Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Graduate Medical Sciences


Professor
Boston University School of Medicine, Graduate Medical Sciences
Chemistry



2013 Boston University: William Fairfield Warren Distinguished Professor
2010 American Chemical Society: Field and Franklin Award


Legacy Support During Closure of the Mass Spectrometry Resource for Biology and Medicine
08/01/2019 - 06/30/2022 (PI)
NIH/National Institute of General Medical Sciences
5R24GM134210-02

Mass Spectrometry based Characterization of (a) O-glycan GAG (b) Enzymatic reaction on physiologically relevant Glycans and (c) Glycovariants and Charge variants of Biologics
04/01/2021 - 03/31/2022 (PI)
Takeda Pharmaceuticals North America, Inc.


Mass Spectrometry analyses, matrix-assisted laser desorption/ionization and electrospray ionization tandem analyses
12/01/2018 - 06/30/2021 (PI)
Nutricia Research B.V


Cellular and humoral immunity in Lyme arthritis
01/08/2019 - 12/31/2020 (Subcontract PI)
Massachusetts General Hospital NIH NIAID
5R01AI144365-02

IPA Agreement for Juan Wei
04/05/2019 - 09/27/2019 (PI)
Department of Veterans Administration, Bedford


MASS SPECTROMETRY RESOURCE FOR BIOLOGY AND MEDICINE
06/01/2016 - 05/31/2019 (PI)
NIH/National Institute of General Medical Sciences
4P41GM104603-20

A Thermo-Fisher Scientific Orbitrap Fusion Lumos Tribrid Mass Spectrometer System
03/06/2018 - 03/05/2019 (PI)
NIH/Office of the Director
1S10OD021728-01A1

Innovative Approach for Identifying Infectious Agents and Autoantigens in RA
07/01/2014 - 06/30/2016 (Subcontract PI)
Massachusetts General Hospital Ounsworth-Fitzg Fdn


MASS SPECTROMETRY RESOURCE FOR BIOLOGY AND MEDICINE
07/01/1997 - 05/31/2016 (PI)
NIH/National Institute of General Medical Sciences
5P41GM104603-19

Proteomics Centers: Proteomics of Inflammation, Immunity and Pulmonary Arterial Hypertension
08/15/2010 - 08/14/2015 (Subcontract PI)
NIH/National Heart, Lung, and Blood Institute NIH NHLBI


Showing 10 of 21 results. Show All Results


Title


Yr Title Project-Sub Proj Pubs
2021 Legacy Support During Closure of the Mass Spectrometry Resource for Biology and Medicine 5R24GM134210-03
2020 Legacy Support During Closure of the Mass Spectrometry Resource for Biology and Medicine 5R24GM134210-02
2019 Legacy Support During Closure of the Mass Spectrometry Resource for Biology and Medicine 1R24GM134210-01
2018 A Thermo-Fisher Scientific Orbitrap Fusion Lumos Tribrid Mass Spectrometer System 1S10OD021728-01A1 2
2017 Mass Spectrometry Resource for Biology and Medicine 3P41GM104603-20S1 148
2016 Mass Spectrometry Resource for Biology and Medicine 4P41GM104603-20 148
2015 Mass Spectrometry Resource for Biology and Medicine 5P41GM104603-19 148
2014 Mass Spectrometry Resource for Biology and Medicine 5P41GM104603-18 148
2013 TAS::75 0872::TAS PROTEOMIC CENTERS: MODIFICATION OF CARDIOVASCULAR PROTEINS BY 268201000031C-5-0-1
2013 Mass Spectrometry Resource for Biology and Medicine 5P41GM104603-17 148
Showing 10 of 417 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Rahimi N, Ho RXY, Chandler KB, De La Cena KOC, Amraei R, Mitchel AJ, Engblom N, Costello CE. The cell adhesion molecule TMIGD1 binds to moesin and regulates tubulin acetylation and cell migration. J Biomed Sci. 2021 Sep 09; 28(1):61.View Related Profiles. PMID: 34503512; PMCID: PMC8427838; DOI: 10.1186/s12929-021-00757-z;
     
  2. Amraei R, Yin W, Napoleon MA, Suder EL, Berrigan J, Zhao Q, Olejnik J, Chandler KB, Xia C, Feldman J, Hauser BM, Caradonna TM, Schmidt AG, Gummuluru S, Mühlberger E, Chitalia V, Costello CE, Rahimi N. CD209L/L-SIGN and CD209/DC-SIGN Act as Receptors for SARS-CoV-2. ACS Cent Sci. 2021 Jul 28; 7(7):1156-1165.View Related Profiles. PMID: 34341769; PMCID: PMC8265543; DOI: 10.1021/acscentsci.0c01537;
     
  3. Pianta A, Chiumento G, Ramsden K, Wang Q, Strle K, Arvikar S, Costello CE, Steere AC. Identification of Novel, Immunogenic HLA-DR-Presented Prevotella copri Peptides in Patients with Rheumatoid Arthritis: Patients with Rheumatoid Arthritis. Arthritis Rheumatol. 2021 May 27. PMID: 34042327
     
  4. Yan W, Song H, Song F, Guo Y, Wu CH, Her AS, Pu Y, Wang S, Naowarojna N, Weitz A, Hendrich MP, Costello CE, Zhang L, Liu P, Zhang YJ. Retraction Note: Endoperoxide formation by an a-ketoglutarate-dependent mononuclear non-haem iron enzyme. Nature. 2021 May; 593(7860):612. PMID: 34012118; PMCID: PMC8183423; DOI: 10.1038/s41586-021-03527-x;
     
  5. Hill MM, Dasari S, Mollee P, Merlini G, Costello CE, Hazenberg BPC, Grogan M, Dispenzieri A, Gertz MA, Kourelis T, McPhail ED. The Clinical Impact of Proteomics in Amyloid Typing. Mayo Clin Proc. 2021 05; 96(5):1122-1127. PMID: 33840526
     
  6. Sebastiani P, Federico A, Morris M, Gurinovich A, Tanaka T, Chandler KB, Andersen SL, Denis G, Costello CE, Ferrucci L, Jennings L, Glass DJ, Monti S, Perls TT. Protein signatures of centenarians and their offspring suggest centenarians age slower than other humans. Aging Cell. 2021 02; 20(2):e13290.View Related Profiles. PMID: 33512769; PMCID: PMC7884029; DOI: 10.1111/acel.13290;
     
  7. Chandler KB, Mehta N, Leon DR, Suscovich TJ, Alter G, Costello CE. Multi-isotype Glycoproteomic Characterization of Serum Antibody Heavy Chains Reveals Isotype- and Subclass-Specific N-Glycosylation Profiles. Mol Cell Proteomics. 2019 Apr; 18(4):686-703. PMID: 33451651
     
  8. Wei J, Tang Y, Ridgeway ME, Park MA, Costello CE, Lin C. Accurate Identification of Isomeric Glycans by Trapped Ion Mobility Spectrometry-Electronic Excitation Dissociation Tandem Mass Spectrometry. Anal Chem. 2020 10 06; 92(19):13211-13220. PMID: 32865981; PMCID: PMC8111820; DOI: 10.1021/acs.analchem.0c02374;
     
  9. Amraie R, Napoleon MA, Yin W, Berrigan J, Suder E, Zhao G, Olejnik J, Gummuluru S, Muhlberger E, Chitalia V, Rahimi N. CD209L/L-SIGN and CD209/DC-SIGN act as receptors for SARS-CoV-2 and are differentially expressed in lung and kidney epithelial and endothelial cells. bioRxiv. 2020 Jun 23.View Related Profiles. PMID: 32607506; PMCID: PMC7325172; DOI: 10.1101/2020.06.22.165803;
     
  10. Azab E, Chandler KB, Uda Y, Sun N, Hussein A, Shuwaikan R, Lu V, Costello CE, McComb ME, Divieti Pajevic P. Osteocytes control myeloid cell proliferation and differentiation through Gsa-dependent and -independent mechanisms. FASEB J. 2020 08; 34(8):10191-10211.View Related Profiles. PMID: 32557809; PMCID: PMC7688590; DOI: 10.1096/fj.202000366R;
     
Showing 10 of 457 results. Show More