Catherine E. Costello, PhD
William Fairfield Warren Distinguished Professor
Boston University School of Medicine
Dept of Biochemistry

PhD, Georgetown University
MS, Georgetown University




Catherine Costello came to Boston University in 1994. That year she established the Center for Biomedical Mass Spectrometry, which has become an internationally recognized research center. She holds her primary appointment in the MED Biochemistry Department, with secondary appointments in the Department of Physiology & Biophysics and the Department of Chemistry. Her research, which focuses on determining the structures and functions of biologically important polymers, has revolutionized an important area of biochemistry by providing insights into the structures of molecules responsible for human disease. She is the author or co-author of more than 300 scientific papers, serves on a number of editorial boards of major journals, and has received numerous awards and honors, including the 2010 Field and Franklin Award from the American Chemical Society, one of the highest honors in her field.

Research Professor
Boston University School of Medicine
Physiology & Biophysics


Director
Boston University School of Medicine
Center for Biomedical Mass Spectrometry


Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Graduate Medical Sciences



2013 Boston University: William Fairfield Warren Distinguished Professor
2010 American Chemical Society: Field and Franklin Award


Mass Spectrometry analyses, matrix-assisted laser desorption/ionization and electrospray ionization tandem analyses
12/01/2018 - 12/01/2020 (PI)
Nutricia Research B.V


Mass Spectrometry Resource for Biology and Medicine
06/01/2016 - 05/31/2019 (PI)
NIH/National Institute of General Medical Sciences
4P41GM104603-20

A Thermo-Fisher Scientific Orbitrap Fusion Lumos Tribrid Mass Spectrometer System
03/06/2018 - 03/05/2019 (PI)
NIH/Office of the Director
1S10OD021728-01A1

Innovative Approach for Identifying Infectious Agents and Autoantigens in RA
07/01/2014 - 06/30/2016 (PI)
Massachusetts General Hospital Ounsworth-Fitzg Fdn


Mass Spectrometry Resource for Biology and Medicine
07/01/1997 - 05/31/2016 (PI)
NIH/National Institute of General Medical Sciences
5P41GM104603-19

Proteomics Centers: Proteomics of Inflammation, Immunity and Pulmonary Arterial Hypertension
08/15/2010 - 08/14/2015 (PI)
NIH/National Heart, Lung, and Blood Institute NIH NHLBI


Innovative Approach to Identify Infectious Agents and Novel Autoantigens in RA
08/01/2012 - 06/30/2014 (PI)
Massachusetts General Hospital Amer College - Rheum


Molecular T Vaginalis Host Interactions im Relevance to Inflammatory Sequelae
07/01/2009 - 06/30/2013 (PI)
The Brigham and Women's Hospital, Inc. NIH NIAID


MALDI-TOF/TOF MS TO SUPPORT BIOMEDICAL RESEARCH
05/01/2012 - 04/30/2013 (PI)
NIH/Office of the Director
1S10OD010724-01

MASS SPECTROMETRY RESOURCE FOR BIOLOGY AND MEDICINE
07/01/1996 - 05/31/2012 (PI)
NIH/National Center for Health Research Resources


Showing 10 of 17 results. Show All Results



Yr Title Project-Sub Proj Pubs
2018 A Thermo-Fisher Scientific Orbitrap Fusion Lumos Tribrid Mass Spectrometer System 1S10OD021728-01A1
2017 Mass Spectrometry Resource for Biology and Medicine 3P41GM104603-20S1 135
2016 Mass Spectrometry Resource for Biology and Medicine 4P41GM104603-20 135
2015 Mass Spectrometry Resource for Biology and Medicine 5P41GM104603-19 135
2014 Mass Spectrometry Resource for Biology and Medicine 5P41GM104603-18 135
2013 TAS::75 0872::TAS PROTEOMIC CENTERS: MODIFICATION OF CARDIOVASCULAR PROTEINS BY 268201000031C-5-0-1
2013 Mass Spectrometry Resource for Biology and Medicine 5P41GM104603-17 135
2012 MALDI-TOF/TOF MS TO SUPPORT BIOMEDICAL RESEARCH 1S10OD010724-01 24
2012 Mass Spectrometry Resource for Biology and Medicine 9P41GM104603-16 135
2011 ATOMIC FORCE MICROSCOPY OF BIOPOLYMERS 5P41RR010888-15-5074 256
Showing 10 of 414 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Brown Chandler K, Costello CE, Rahimi N. Glycosylation in the Tumor Microenvironment: Implications for Tumor Angiogenesis and Metastasis. Cells. 2019 Jun 05; 8(6).View Related Profiles. PMID: 31195728.
     
  2. Magistrado-Coxen P, Aqeel Y, Lopez A, Haserick JR, Urbanowicz BR, Costello CE, Samuelson J. The most abundant cyst wall proteins of Acanthamoeba castellanii are lectins that bind cellulose and localize to distinct structures in developing and mature cyst walls. PLoS Negl Trop Dis. 2019 May; 13(5):e0007352.View Related Profiles. PMID: 31095564.
     
  3. Campbell MP, Abrahams JL, Rapp E, Struwe WB, Costello CE, Novotny M, Ranzinger R, York WS, Kolarich D, Rudd PM, Kettner C. The minimum information required for a glycomics experiment (MIRAGE) project: LC guidelines. Glycobiology. 2019 May 01; 29(5):349-354. PMID: 30778580.
     
  4. McDonald AJ, Leon DR, Markham KA, Wu B, Heckendorf CF, Schilling K, Showalter HD, Andrews PC, McComb ME, Pushie MJ, Costello CE, Millhauser GL, Harris DA. Altered Domain Structure of the Prion Protein Caused by Cu2+ Binding and Functionally Relevant Mutations: Analysis by Cross-Linking, MS/MS, and NMR. Structure. 2019 Jun 04; 27(6):907-922.e5.View Related Profiles. PMID: 30956132.
     
  5. Shao D, Yao C, Kim MH, Fry J, Cohen RA, Costello CE, Matsui R, Seta F, McComb ME, Bachschmid MM. Improved mass spectrometry-based activity assay reveals oxidative and metabolic stress as sirtuin-1 regulators. Redox Biol. 2019 04; 22:101150.View Related Profiles. PMID: 30877853.
     
  6. Nguyen DN, Xu B, Stanfield RL, Bailey JK, Horiya S, Temme JS, Leon DR, LaBranche CC, Montefiori DC, Costello CE, Wilson IA, Krauss IJ. Oligomannose Glycopeptide Conjugates Elicit Antibodies Targeting the Glycan Core Rather than Its Extremities. ACS Cent Sci. 2019 Feb 27; 5(2):237-249. PMID: 30834312.
     
  7. Wei J, Wu J, Tang Y, Ridgeway ME, Park MA, Costello CE, Zaia J, Lin C. Characterization and Quantification of Highly Sulfated Glycosaminoglycan Isomers by Gated-Trapped Ion Mobility Spectrometry Negative Electron Transfer Dissociation MS/MS. Anal Chem. 2019 Feb 19; 91(4):2994-3001.View Related Profiles. PMID: 30649866.
     
  8. Chandler KB, Mehta N, Leon DR, Suscovich TJ, Alter G, Costello CE. Multi-isotype Glycoproteomic Characterization of Serum Antibody Heavy Chains Reveals Isotype- and Subclass-Specific N-Glycosylation Profiles. Mol Cell Proteomics. 2019 Apr; 18(4):686-703. PMID: 30659065.
     
  9. Bandini G, Leon DR, Hoppe CM, Zhang Y, Agop-Nersesian C, Shears MJ, Mahal LK, Routier FH, Costello CE, Samuelson J. O-Fucosylation of thrombospondin-like repeats is required for processing of microneme protein 2 and for efficient host cell invasion by Toxoplasma gondii tachyzoites. J Biol Chem. 2019 02 08; 294(6):1967-1983.View Related Profiles. PMID: 30538131.
     
  10. Ho RX, Meyer RD, Chandler KB, Ersoy E, Park M, Bondzie PA, Rahimi N, Xu H, Costello CE, Rahimi N. MINAR1 is a Notch2-binding protein that inhibits angiogenesis and breast cancer growth. J Mol Cell Biol. 2018 06 01; 10(3):195-204.View Related Profiles. PMID: 29329397.
     
Showing 10 of 439 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 419 publications over 40 distinct years, with a maximum of 29 publications in 2006

YearPublications
19802
19813
19825
19836
19845
19854
19868
19872
19889
19893
199010
19916
19928
19937
19947
19955
19967
199710
19982
199913
200010
200115
200217
200314
200419
200519
200629
200718
200814
200913
201015
201114
201210
201319
201411
201515
201621
20177
20189
20198
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