Profile

PhD, Boston University
MS, Tufts University




Endothelin and Angiotensin Receptor Signaling in Pulmonary Hypertension
12/01/1981 - 11/30/2014 (PI)
NIH/National Heart, Lung, and Blood Institute
5R01HL025776-28

Pre- and Postdoctoral Training in Biochemistry of Aging
09/01/1985 - 04/30/2013 (PI)
NIH/National Institute on Aging
3T32AG000115-25S1




Yr Title Project-Sub Proj Pubs
2013 Endothelin and Angiotensin Receptor Signaling in Pulmonary Hypertension 5R01HL025776-28 48
2012 Pre- and Postdoctoral Training in Biochemistry of Aging 3T32AG000115-25S1 15
2012 Endothelin and Angiotensin Receptor Signaling in Pulmonary Hypertension 5R01HL025776-27 48
2011 PROTEOMIC CHANGES IN MUSCLE CELLS WITH PULMONARY HYPERTENSION 5P41RR010888-15-5162 236
2011 Pre- and Postdoctoral Training in Biochemistry of Aging 5T32AG000115-25 15
2011 Endothelin and Angiotensin Receptor Signaling in Pulmonary Hypertension 5R01HL025776-26 48
2011 Endothelin and Angiotensin Receptor Signaling in Pulmonary Hypertension 5R01HL025776-26 48
2011 Endothelin and Angiotensin Receptor Signaling in Pulmonary Hypertension 5R01HL025776-26 48
2011 Endothelin and Angiotensin Receptor Signaling in Pulmonary Hypertension 5R01HL025776-26 48
2010 Pre- and Postdoctoral Training in Biochemistry of Aging 5T32AG000115-24 15
Showing 10 of 63 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Ghosh S, Gupta M, Xu W, Mavrakis DA, Janocha AJ, Comhair SA, Haque MM, Stuehr DJ, Yu J, Polgar P, Naga Prasad SV, Erzurum SC. Phosphorylation inactivation of endothelial nitric oxide synthesis in pulmonary arterial hypertension. Am J Physiol Lung Cell Mol Physiol. 2016 Jun 01; 310(11):L1199-205. PMID: 27130529; PMCID: PMC4935470; DOI: 10.1152/ajplung.00092.2016;.
  2. Wilson JL, Yu J, Taylor L, Polgar P. Hyperplastic Growth of Pulmonary Artery Smooth Muscle Cells from Subjects with Pulmonary Arterial Hypertension Is Activated through JNK and p38 MAPK. PLoS One. 2015; 10(4):e0123662.View Related Profiles. PMID: 25905460; PMCID: PMC4408087; DOI: 10.1371/journal.pone.0123662;.
  3. Yu J, Wilson J, Taylor L, Polgar P. DNA microarray and signal transduction analysis in pulmonary artery smooth muscle cells from heritable and idiopathic pulmonary arterial hypertension subjects. J Cell Biochem. 2015 Mar; 116(3):386-97.View Related Profiles. PMID: 25290246; PMCID: PMC4391824; DOI: 10.1002/jcb.24987;.
  4. Yao C, Yu J, Taylor L, Polgar P, McComb ME, Costello CE. Protein Expression by Human Pulmonary Artery Smooth Muscle Cells Containing a BMPR2 Mutation and the Action of ET-1 as Determined by Proteomic Mass Spectrometry. Int J Mass Spectrom. 2015 Feb 15; 378:347-359.View Related Profiles. PMID: 25866469.
  5. Wilson JL, Rupasinghe C, Usheva A, Warburton R, Kaplan C, Taylor L, Hill N, Mierke DF, Polgar P. Modulating the dysregulated migration of pulmonary arterial hypertensive smooth muscle cells with motif mimicking cell permeable peptides. Curr Top Pept Protein Res. 2015; 16:1-17.View Related Profiles. PMID: 27274622.
  6. Yu J, Rupasinghe C, Wilson JL, Taylor L, Rahimi N, Mierke D, Polgar P. Targeting receptor tyrosine kinases and their downstream signaling with cell-penetrating peptides in human pulmonary artery smooth muscle and endothelial cells. Chem Biol Drug Des. 2015 May; 85(5):586-97.View Related Profiles. PMID: 25298192; PMCID: PMC4390552; DOI: 10.1111/cbdd.12446;.
  7. Green DS, Rupasinghe C, Warburton R, Wilson JL, Sallum CO, Taylor L, Yatawara A, Mierke D, Polgar P, Hill N. A cell permeable peptide targeting the intracellular loop 2 of endothelin B receptor reduces pulmonary hypertension in a hypoxic rat model. PLoS One. 2013; 8(11):e81309.View Related Profiles. PMID: 24312288; PMCID: PMC3842336; DOI: 10.1371/journal.pone.0081309;.
  8. Yatawara A, Wilson JL, Taylor L, Polgar P, Mierke DF. C-terminus of ETA/ETB receptors regulate endothelin-1 signal transmission. J Pept Sci. 2013 Apr; 19(4):257-62.View Related Profiles. PMID: 23436727; PMCID: PMC3770155; DOI: 10.1002/psc.2499;.
  9. Yu J, Taylor L, Wilson J, Comhair S, Erzurum S, Polgar P. Altered expression and signal transduction of endothelin-1 receptors in heritable and idiopathic pulmonary arterial hypertension. J Cell Physiol. 2013 Feb; 228(2):322-9.View Related Profiles. PMID: 22688668; PMCID: PMC3496420; DOI: 10.1002/jcp.24132;.
  10. Kao PF, Banigan MG, Vanderburg CR, McKee AC, Polgar PR, Seshadri S, Delalle I. Increased expression of TrkB and Capzb2 accompanies preserved cognitive status in early Alzheimer disease pathology. J Neuropathol Exp Neurol. 2012 Jul; 71(7):654-64.View Related Profiles. PMID: 22710966; PMCID: PMC3398703; DOI: 10.1097/NEN.0b013e31825d06b7;.
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