Keywords
Last Name

Ronald H. Goldstein, MD

TitleProfessor
InstitutionBoston University School of Medicine
DepartmentMedicine
DivisionPulmonary, Allergy, Sleep & Critical Care Medicine
Address72 E. Concord St Housman (R)
Boston MA 02118
Phone(617) 638-4860
Other Positions
TitleGraduate Faculty (Primary Mentor of Grad Students)
InstitutionBoston University School of Medicine, Division of Graduate Medical Sciences

TitleResearch Assistant Professor
InstitutionBoston University School of Medicine
DepartmentBiochemistry

InstitutionVA Boston Healthcare System

 Research Expertise & Professional Interests
Our laboratory is exploring the regulation of the alveolar matrix during the development of early emphysema and fibrosis. The loss of matrix substances results in emphysema whereas the excessive deposition of matrix substances results in pulmonary fibrosis. Employing the techniques of cellular and molecular biology, we are developing methods to modulating the levels of collagen, elastin and other key matrix substances in the alveolar wall. These approaches are studied in wild type and transgenic murine models of emphysema and fibrosis.

We have extensive experience in the diagnosis and management of individuals with pulmonary fibrosis. In human studies, our clinical experimental interest involves the use of novel substances to treat idiopathic pulmonary fibrosis (IPF). We participate in several clinical studies to evaluate the efficacy of these agents in the pathogenesis of IPF.

Research special interests include: Pulmonary Matrix Biology related to Pulmonary Fibrosis and Emphysema

Clinical special interests include: Pulmonary Fibrosis

 Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Maron BA, Hess E, Maddox TM, Opotowsky AR, Tedford RJ, Lahm T, Joynt KE, Kass DJ, Stephens T, Stanislawski MA, Swenson ER, Goldstein RH, Leopold JA, Zamanian RT, Elwing JM, Plomondon ME, Grunwald GK, BarĂ³n AE, Rumsfeld JS, Choudhary G. Association of Borderline Pulmonary Hypertension With Mortality and Hospitalization in a Large Patient Cohort: Insights From the Veterans Affairs Clinical Assessment, Reporting, and Tracking Program. Circulation. 2016 Mar 29; 133(13):1240-8. PMID: 26873944.
    View in: PubMed
  2. Berry NC, Manyoo A, Oldham WM, Stephens TE, Goldstein RH, Waxman AB, Tracy JA, Leary PJ, Leopold JA, Kinlay S, Opotowsky AR, Systrom DM, Maron BA. Protocol for exercise hemodynamic assessment: performing an invasive cardiopulmonary exercise test in clinical practice. Pulm Circ. 2015 Dec; 5(4):610-8. PMID: 26697168.
    View in: PubMed
  3. Maron BA, Goldstein RH, Rounds SI, Shapiro S, Jankowich M, Garshick E, Moy ML, Gagnon D, Choudhary G. Study design and rationale for investigating phosphodiesterase type 5 inhibition for the treatment of pulmonary hypertension due to chronic obstructive lung disease: the TADA-PHiLD (TADAlafil for Pulmonary Hypertension associated with chronic obstructive Lung Disease) trial. Pulm Circ. 2013 Dec; 3(4):889-97. PMID: 25006405.
    View in: PubMed
  4. Golan-Gerstl R, Wallach-Dayan SB, Zisman P, Cardoso WV, Goldstein RH, Breuer R. Cellular FLICE-like inhibitory protein deviates myofibroblast fas-induced apoptosis toward proliferation during lung fibrosis. Am J Respir Cell Mol Biol. 2012 Sep; 47(3):271-9. PMID: 22582174.
    View in: PubMed
  5. Yu J, Taylor L, Rich C, Toselli P, Stone P, Green D, Warburton R, Hill N, Goldstein R, Polgar P. Transgenic expression of an altered angiotensin type I AT1 receptor resulting in marked modulation of vascular type I collagen. J Cell Physiol. 2012 May; 227(5):2013-21. PMID: 21751211.
    View in: PubMed
  6. Brooks WW, Shen S, Conrad CH, Goldstein RH, Deng LL, Bing OH. Transcriptional changes associated with recovery from heart failure in the SHR. J Mol Cell Cardiol. 2010 Sep; 49(3):390-401. PMID: 20547165.
    View in: PubMed
  7. Brooks WW, Shen SS, Conrad CH, Goldstein RH, Bing OH. Transition from compensated hypertrophy to systolic heart failure in the spontaneously hypertensive rat: Structure, function, and transcript analysis. Genomics. 2010 Feb; 95(2):84-92. PMID: 20006699.
    View in: PubMed
  8. Kuang PP, Zhang XH, Rich CB, Foster JA, Subramanian M, Goldstein RH. Activation of elastin transcription by transforming growth factor-beta in human lung fibroblasts. Am J Physiol Lung Cell Mol Physiol. 2007 Apr; 292(4):L944-52. PMID: 17209135.
    View in: PubMed
  9. Subramanian M, Kuang PP, Wei L, Rishikof DC, Liu H, Goldstein RH. Modulation of amino acid uptake by TGF-beta in lung myofibroblasts. J Cell Biochem. 2006 Sep 1; 99(1):71-8. PMID: 16598748.
    View in: PubMed
  10. Kuang PP, Joyce-Brady M, Zhang XH, Jean JC, Goldstein RH. Fibulin-5 gene expression in human lung fibroblasts is regulated by TGF-beta and phosphatidylinositol 3-kinase activity. Am J Physiol Cell Physiol. 2006 Dec; 291(6):C1412-21. PMID: 16837650.
    View in: PubMed
  11. Serlin DM, Kuang PP, Subramanian M, O'Regan A, Li X, Berman JS, Goldstein RH. Interleukin-1beta induces osteopontin expression in pulmonary fibroblasts. J Cell Biochem. 2006 Feb 15; 97(3):519-29. PMID: 16211580.
    View in: PubMed
  12. Rishikof DC, Lucey EC, Kuang PP, Snider GL, Goldstein RH. Induction of the myofibroblast phenotype following elastolytic injury to mouse lung. Histochem Cell Biol. 2006 May; 125(5):527-34. PMID: 16328432.
    View in: PubMed
  13. Chen P, Marsilio E, Goldstein RH, Yannas IV, Spector M. Formation of lung alveolar-like structures in collagen-glycosaminoglycan scaffolds in vitro. Tissue Eng. 2005 Sep-Oct; 11(9-10):1436-48. PMID: 16259599.
    View in: PubMed
  14. Berk JL, Hatch CA, Morris SM, Stone PJ, Goldstein RH. Hypoxia suppresses elastin repair by rat lung fibroblasts. Am J Physiol Lung Cell Mol Physiol. 2005 Dec; 289(6):L931-6. PMID: 16055482.
    View in: PubMed
  15. Kuang PP, Lucey E, Rishikof DC, Humphries DE, Bronsnick D, Goldstein RH. Engraftment of neonatal lung fibroblasts into the normal and elastase-injured lung. Am J Respir Cell Mol Biol. 2005 Oct; 33(4):371-7. PMID: 16037486.
    View in: PubMed
  16. Kuang PP, Goldstein RH. Regulation of elastin gene transcription by proteasome dysfunction. Am J Physiol Cell Physiol. 2005 Sep; 289(3):C766-73. PMID: 15814588.
    View in: PubMed
  17. Rishikof DC, Kuang PP, Subramanian M, Goldstein RH. Methods for measuring type I collagen synthesis in vitro. Methods Mol Med. 2005; 117:129-40. PMID: 16118450.
    View in: PubMed
  18. Buczek-Thomas JA, Lucey EC, Stone PJ, Chu CL, Rich CB, Carreras I, Goldstein RH, Foster JA, Nugent MA. Elastase mediates the release of growth factors from lung in vivo. Am J Respir Cell Mol Biol. 2004 Sep; 31(3):344-50. PMID: 15191913.
    View in: PubMed
  19. Rishikof DC, Ricupero DA, Liu H, Goldstein RH. Phenylbutyrate decreases type I collagen production in human lung fibroblasts. J Cell Biochem. 2004 Mar 1; 91(4):740-8. PMID: 14991765.
    View in: PubMed
  20. Kuang PP, Goldstein RH, Liu Y, Rishikof DC, Jean JC, Joyce-Brady M. Coordinate expression of fibulin-5/DANCE and elastin during lung injury repair. Am J Physiol Lung Cell Mol Physiol. 2003 Nov; 285(5):L1147-52. PMID: 12909585.
    View in: PubMed
  21. Kuang PP, Goldstein RH. Regulation of elastin gene transcription by interleukin-1 beta-induced C/EBP beta isoforms. Am J Physiol Cell Physiol. 2003 Dec; 285(6):C1349-55. PMID: 12890646.
    View in: PubMed
  22. Lucey EC, Goldstein RH, Breuer R, Rexer BN, Ong DE, Snider GL. Retinoic acid does not affect alveolar septation in adult FVB mice with elastase-induced emphysema. Respiration. 2003 Mar-Apr; 70(2):200-5. PMID: 12740518.
    View in: PubMed
  23. Izbicki G, Or R, Christensen TG, Segel MJ, Fine A, Goldstein RH, Breuer R. Bleomycin-induced lung fibrosis in IL-4-overexpressing and knockout mice. Am J Physiol Lung Cell Mol Physiol. 2002 Nov; 283(5):L1110-6. PMID: 12376365.
    View in: PubMed
  24. Brooks WW, Bing OH, Gaasch WH, Karlinsky JB, Goldstein RH, Conrad CH. Comparison of contractile function of diaphragm and cardiac muscle in response to paired electrical stimulation. Comp Biochem Physiol A Mol Integr Physiol. 2002 Sep; 133(1):53-62. PMID: 12160872.
    View in: PubMed
  25. Tzurel A, Segel MJ, Or R, Goldstein RH, Breuer R. Halofuginone does not reduce fibrosis in bleomycin-induced lung injury. Life Sci. 2002 Aug 23; 71(14):1599-606. PMID: 12137906.
    View in: PubMed
  26. Kuang PP, Berk JL, Rishikof DC, Foster JA, Humphries DE, Ricupero DA, Goldstein RH. NF-kappaB induced by IL-1beta inhibits elastin transcription and myofibroblast phenotype. Am J Physiol Cell Physiol. 2002 Jul; 283(1):C58-65. PMID: 12055073.
    View in: PubMed
  27. Lucey EC, Keane J, Kuang PP, Snider GL, Goldstein RH. Severity of elastase-induced emphysema is decreased in tumor necrosis factor-alpha and interleukin-1beta receptor-deficient mice. Lab Invest. 2002 Jan; 82(1):79-85. PMID: 11796828.
    View in: PubMed
  28. Rishikof DC, Ricupero DA, Kuang PP, Liu H, Goldstein RH. Interleukin-4 regulates connective tissue growth factor expression in human lung fibroblasts. J Cell Biochem. 2002; 85(3):496-504. PMID: 11967989.
    View in: PubMed
  29. Ricupero DA, Poliks CF, Rishikof DC, Kuang PP, Goldstein RH. Apigenin decreases expression of the myofibroblast phenotype. FEBS Lett. 2001 Sep 28; 506(1):15-21. PMID: 11591363.
    View in: PubMed
  30. Ricupero DA, Poliks CF, Rishikof DC, Cuttle KA, Kuang PP, Goldstein RH. Phosphatidylinositol 3-kinase-dependent stabilization of alpha1(I) collagen mRNA in human lung fibroblasts. Am J Physiol Cell Physiol. 2001 Jul; 281(1):C99-C105. PMID: 11401831.
    View in: PubMed
  31. Berkman N, Kremer S, Or R, Lossos IS, Christensen TG, Goldstein RH, Breuer R. Human recombinant interferon-alpha2a and interferon-alphaA/D have different effects on bleomycin-induced lung injury. Respiration. 2001; 68(2):169-77. PMID: 11287832.
    View in: PubMed
  32. Segel MJ, Or R, Tzurel A, Lucey EC, Goldstein RH, Izbicki G, Breuer R. All-trans-retinoic acid (ATRA) is of no benefit in bleomycin-induced lung injury. Pulm Pharmacol Ther. 2001; 14(5):403-7. PMID: 11603953.
    View in: PubMed
  33. Lossos IS, Izbicki G, Or R, Goldstein RH, Breuer R. The effect of suramin on bleomycin-induced lung injury. Life Sci. 2000 Oct 27; 67(23):2873-81. PMID: 11106002.
    View in: PubMed
  34. Berk JL, Hatch CA, Goldstein RH. Hypoxia inhibits amino acid uptake in human lung fibroblasts. J Appl Physiol (1985). 2000 Oct; 89(4):1425-31. PMID: 11007578.
    View in: PubMed
  35. Ricupero DA, Romero JR, Rishikof DC, Goldstein RH. Des-Arg(10)-kallidin engagement of the B1 receptor stimulates type I collagen synthesis via stabilization of connective tissue growth factor mRNA. J Biol Chem. 2000 Apr 28; 275(17):12475-80. PMID: 10777533.
    View in: PubMed
  36. Ricupero DA, Rishikof DC, Kuang PP, Poliks CF, Goldstein RH. Regulation of connective tissue growth factor expression by prostaglandin E(2). Am J Physiol. 1999 Dec; 277(6 Pt 1):L1165-71. PMID: 10600887.
    View in: PubMed
  37. Rishikof DC, Ricupero DA, Poliks CF, Goldstein RH. Amino acid availability regulates type I procollagen accumulation in human lung fibroblasts. J Cell Biochem. 1999 Oct 1; 75(1):130-7. PMID: 10462711.
    View in: PubMed
  38. Berk JL, Massoomi N, Hatch C, Goldstein RH. Hypoxia downregulates tropoelastin gene expression in rat lung fibroblasts by pretranslational mechanisms. Am J Physiol. 1999 Sep; 277(3 Pt 1):L566-72. PMID: 10484464.
    View in: PubMed
  39. Laxer U, Lossos IS, Gillis S, Or R, Christensen TG, Goldstein RH, Breuer R. The effect of enoxaparin on bleomycin-induced lung injury in mice. Exp Lung Res. 1999 Sep; 25(6):531-41. PMID: 10533678.
    View in: PubMed
  40. Kremer S, Breuer R, Lossos IS, Berkman N, Christensen TG, Connor MW, Goldstein RH, Or R. Effect of immunomodulators on bleomycin-induced lung injury. Respiration. 1999; 66(5):455-62. PMID: 10516543.
    View in: PubMed
  41. Rishikof DC, Krupsky M, Goldstein RH. The effect of prostaglandin E2 on cystine uptake and glutathione synthesis by human lung fibroblasts. Biochim Biophys Acta. 1998 Oct 21; 1405(1-3):155-60. PMID: 9784627.
    View in: PubMed
  42. Lucey EC, Goldstein RH, Stone PJ, Snider GL. Remodeling of alveolar walls after elastase treatment of hamsters. Results of elastin and collagen mRNA in situ hybridization. Am J Respir Crit Care Med. 1998 Aug; 158(2):555-64. PMID: 9700135.
    View in: PubMed
  43. Rishikof DC, Kuang PP, Poliks C, Goldstein RH. Regulation of type I collagen mRNA in lung fibroblasts by cystine availability. Biochem J. 1998 Apr 15; 331 ( Pt 2):417-22. PMID: 9531479.
    View in: PubMed
  44. Bing OH, Ngo HQ, Humphries DE, Robinson KG, Lucey EC, Carver W, Brooks WW, Conrad CH, Hayes JA, Goldstein RH. Localization of alpha1(I) collagen mRNA in myocardium from the spontaneously hypertensive rat during the transition from compensated hypertrophy to failure. J Mol Cell Cardiol. 1997 Sep; 29(9):2335-44. PMID: 9299357.
    View in: PubMed
  45. Krupsky M, Kuang PP, Goldstein RH. Regulation of type I collagen mRNA by amino acid deprivation in human lung fibroblasts. J Biol Chem. 1997 May 23; 272(21):13864-8. PMID: 9153245.
    View in: PubMed
  46. Berkman N, Goldstein RH, Breuer R. Bleomycin-induced lung injury is enhanced by interferon-alpha. Life Sci. 1997; 60(26):PL415-21. PMID: 9199490.
    View in: PubMed
  47. Ben Yehuda A, Lossos IS, Or R, Ben Chetrit E, Goldstein RH, Conner MW, Breuer R. Colchicine does not ameliorate bleomycin-induced pulmonary injury in hamsters. Pulm Pharmacol Ther. 1997; 10(1):61-5. PMID: 9344834.
    View in: PubMed
  48. Berk JL, Massoomi N, Krupsky M, Goldstein RH. Effect of okadaic acid on elastin gene expression in interstitial lung fibroblasts. Am J Physiol. 1996 Dec; 271(6 Pt 1):L939-48. PMID: 8997264.
    View in: PubMed
  49. Agarwal AR, Goldstein RH, Lucey E, Ngo HQ, Smith BD. Cell-specific expression of the alpha 1 (I) collagen promoter-CAT transgene in skin and lung: a response to TGF-beta subcutaneous injection and bleomycin endotracheal instillation. J Cell Biochem. 1996 Nov 1; 63(2):135-48. PMID: 8913866.
    View in: PubMed
  50. Roy R, Polgar P, Wang Y, Goldstein RH, Taylor L, Kagan HM. Regulation of lysyl oxidase and cyclooxygenase expression in human lung fibroblasts: interactions among TGF-beta, IL-1 beta, and prostaglandin E. J Cell Biochem. 1996 Sep 1; 62(3):411-7. PMID: 8872612.
    View in: PubMed
  51. Bloom BB, Humphries DE, Kuang PP, Fine A, Goldstein RH. Structure and expression of the promoter for the R4/ALK5 human type I transforming growth factor-beta receptor: regulation by TGF-beta. Biochim Biophys Acta. 1996 Jul 24; 1312(3):243-8. PMID: 8703994.
    View in: PubMed
  52. Lossos IS, Or R, Goldstein RH, Conner MW, Breuer R. Amelioration of bleomycin-induced pulmonary injury by cyclosporin A. Exp Lung Res. 1996 May-Jun; 22(3):337-49. PMID: 8792125.
    View in: PubMed
  53. Lucey EC, Ngo HQ, Agarwal A, Smith BD, Snider GL, Goldstein RH. Differential expression of elastin and alpha 1(I) collagen mRNA in mice with bleomycin-induced pulmonary fibrosis. Lab Invest. 1996 Jan; 74(1):12-20. PMID: 8569173.
    View in: PubMed
  54. Krupsky M, Fine A, Kuang PP, Berk JL, Goldstein RH. Regulation of type I collagen production by insulin and transforming growth factor-beta in human lung fibroblasts. Connect Tissue Res. 1996; 34(1):53-62. PMID: 8835848.
    View in: PubMed
  55. Goldstein RH, Fine A. Potential therapeutic initiatives for fibrogenic lung diseases. Chest. 1995 Sep; 108(3):848-55. PMID: 7656643.
    View in: PubMed
  56. Fine A, Panchenko MP, Smith BD, Yu Q, Goldstein RH. Discordant regulation of transforming growth factor-beta receptors by prostaglandin E2. Biochim Biophys Acta. 1995 Mar 14; 1261(1):19-24. PMID: 7893757.
    View in: PubMed
  57. Boak AM, Roy R, Berk J, Taylor L, Polgar P, Goldstein RH, Kagan HM. Regulation of lysyl oxidase expression in lung fibroblasts by transforming growth factor-beta 1 and prostaglandin E2. Am J Respir Cell Mol Biol. 1994 Dec; 11(6):751-5. PMID: 7946403.
    View in: PubMed
  58. Krupsky M, Fine A, Berk JL, Goldstein RH. Retinoic acid-induced inhibition of type I collagen gene expression by human lung fibroblasts. Biochim Biophys Acta. 1994 Oct 18; 1219(2):335-41. PMID: 7918630.
    View in: PubMed
  59. Humphries DE, Bloom BB, Fine A, Goldstein RH. Structure and expression of the promoter for the human type II transforming growth factor-beta receptor. Biochem Biophys Res Commun. 1994 Sep 15; 203(2):1020-7. PMID: 8093019.
    View in: PubMed
  60. Matsui R, Goldstein RH, Mihal K, Brody JS, Steele MP, Fine A. Type I collagen formation in rat type II alveolar cells immortalised by viral gene products. Thorax. 1994 Mar; 49(3):201-6. PMID: 8202874.
    View in: PubMed
  61. Jackson BA, Goldstein RH, Roy R, Cozzani M, Taylor L, Polgar P. Effects of transforming growth factor beta and interleukin-1 beta on expression of cyclooxygenase 1 and 2 and phospholipase A2 mRNA in lung fibroblasts and endothelial cells in culture. Biochem Biophys Res Commun. 1993 Dec 30; 197(3):1465-74. PMID: 8280164.
    View in: PubMed
  62. Krupsky M, Fine A, Berk JL, Goldstein RH. The effect of retinoic acid on amino acid uptake and protein synthesis by lung fibroblasts. J Biol Chem. 1993 Nov 5; 268(31):23283-8. PMID: 8226851.
    View in: PubMed
  63. Ritzenthaler JD, Goldstein RH, Fine A, Smith BD. Regulation of the alpha 1(I) collagen promoter via a transforming growth factor-beta activation element. J Biol Chem. 1993 Jun 25; 268(18):13625-31. PMID: 8514794.
    View in: PubMed
  64. Fine A, Goldstein RH. Regulation of type I collagen mRNA translation by TGF-beta. Reg Immunol. 1993 May-Aug; 5(3-4):218-24. PMID: 8240938.
    View in: PubMed
  65. Fine A, Matsui R, Zhan X, Poliks CF, Smith BD, Goldstein RH. Discordant regulation of human type I collagen genes by prostaglandin E2. Biochim Biophys Acta. 1992 Apr 30; 1135(1):67-72. PMID: 1375511.
    View in: PubMed
  66. Ritzenthaler JD, Goldstein RH, Fine A, Lichtler A, Rowe DW, Smith BD. Transforming-growth-factor-beta activation elements in the distal promoter regions of the rat alpha 1 type I collagen gene. Biochem J. 1991 Nov 15; 280 ( Pt 1):157-62. PMID: 1741743.
    View in: PubMed
  67. Goldstein RH. Control of type I collagen formation in the lung. Am J Physiol. 1991 Aug; 261(2 Pt 1):L29-40. PMID: 1872414.
    View in: PubMed
  68. Villanueva AG, Farber HW, Rounds S, Goldstein RH. Stimulation of fibroblast collagen and total protein formation by an endothelial cell-derived factor. Circ Res. 1991 Jul; 69(1):134-41. PMID: 2054930.
    View in: PubMed
  69. Fine A, Goldstein RH. Mechanisms of transforming growth factor-beta-induced collagen formation by human lung fibroblasts. Chest. 1991 Mar; 99(3 Suppl):84S. PMID: 1997287.
    View in: PubMed
  70. Berk JL, Franzblau C, Goldstein RH. Recombinant interleukin-1 beta inhibits elastin formation by a neonatal rat lung fibroblast subtype. J Biol Chem. 1991 Feb 15; 266(5):3192-7. PMID: 1993692.
    View in: PubMed
  71. Goldstein RH, Fine A, Farnsworth LJ, Poliks C, Polgar P. Phorbol ester-induced inhibition of collagen accumulation by human lung fibroblasts. J Biol Chem. 1990 Aug 15; 265(23):13623-8. PMID: 2380178.
    View in: PubMed
  72. Fine A, Poliks CF, Smith BD, Goldstein RH. The accumulation of type I collagen mRNAs in human embryonic lung fibroblasts stimulated by transforming growth factor-beta. Connect Tissue Res. 1990; 24(3-4):237-47. PMID: 2376126.
    View in: PubMed
  73. Fine A, Poliks CF, Donahue LP, Smith BD, Goldstein RH. The differential effect of prostaglandin E2 on transforming growth factor-beta and insulin-induced collagen formation in lung fibroblasts. J Biol Chem. 1989 Oct 15; 264(29):16988-91. PMID: 2676997.
    View in: PubMed
  74. Karlinsky JB, Goldstein RH. Regulation of sulfated glycosaminoglycan production by prostaglandin E2 in cultured lung fibroblasts. J Lab Clin Med. 1989 Aug; 114(2):176-84. PMID: 2502590.
    View in: PubMed
  75. Goldstein RH, Poliks CF, Pilch PF, Smith BD, Fine A. Stimulation of collagen formation by insulin and insulin-like growth factor I in cultures of human lung fibroblasts. Endocrinology. 1989 Feb; 124(2):964-70. PMID: 2463909.
    View in: PubMed
  76. Fine A, Goldstein RH. The effect of PGE2 on the activation of quiescent lung fibroblasts. Prostaglandins. 1987 Jun; 33(6):903-13. PMID: 2823317.
    View in: PubMed
  77. Fine A, Goldstein RH. The effect of transforming growth factor-beta on cell proliferation and collagen formation by lung fibroblasts. J Biol Chem. 1987 Mar 15; 262(8):3897-902. PMID: 3493244.
    View in: PubMed
  78. Karlinsky JB, Goldstein RH, Ojserkis B, Snider GL. Lung mechanics and connective tissue levels in starvation-induced emphysema in hamsters. Am J Physiol. 1986 Aug; 251(2 Pt 2):R282-8. PMID: 3740310.
    View in: PubMed
  79. Goldstein RH, Sakowski S, Meeker D, Franzblau C, Polgar P. The effect of prostaglandin E2 (PGE2) on amino acid uptake and protein formation by lung fibroblasts. J Biol Chem. 1986 Jul 5; 261(19):8734-7. PMID: 3459727.
    View in: PubMed
  80. Karlinsky JB, Goldstein RH, Catanese A, Snider GL. Young hamsters are more resistant than adults to endotracheally instilled porcine pancreatic elastase. Exp Lung Res. 1986; 11(3):229-43. PMID: 3640708.
    View in: PubMed
  81. Goldstein RH, Fine A. Fibrotic reactions in the lung: the activation of the lung fibroblast. Exp Lung Res. 1986; 11(4):245-61. PMID: 3536465.
    View in: PubMed
  82. Rinaldo J, Goldstein RH, Snider GL. Modification of oxygen toxicity after lung injury by bleomycin in hamsters. Am Rev Respir Dis. 1982 Dec; 126(6):1030-3. PMID: 6185022.
    View in: PubMed
  83. Goldstein RH, Miller K, Glassroth J, Linscott R, Snider GL, Franzblau C, Polgar P. Influence of asbestos fibers on collagen and prostaglandin production in fibroblast and macrophage co-cultures. J Lab Clin Med. 1982 Nov; 100(5):778-85. PMID: 7130833.
    View in: PubMed
  84. Goldstein RH, Polgar P. The effect and interaction of bradykinin and prostaglandins on protein and collagen production by lung fibroblasts. J Biol Chem. 1982 Aug 10; 257(15):8630-3. PMID: 6954152.
    View in: PubMed
  85. Fedullo AJ, Karlinsky JB, Snider GL, Goldstein RH. Lung statics and connective tissues after penicillamine in bleomycin-treated hamsters. J Appl Physiol Respir Environ Exerc Physiol. 1980 Dec; 49(6):1083-90. PMID: 6160133.
    View in: PubMed
  86. Karlinsky JB, Goldstein RH. Fibrotic lung disease--a perspective. J Lab Clin Med. 1980 Dec; 96(6):939-42. PMID: 6159433.
    View in: PubMed
  87. Goldstein RH, Lucey EC, Franzblau C, Snider GL. Failure of mechanical properties to parallel changes in lung connective tissue composition in bleomycin-induced pulmonary fibrosis in hamsters. Am Rev Respir Dis. 1979 Jul; 120(1):67-73. PMID: 88916.
    View in: PubMed
  88. Goldstein RH, Faris B, Hu CL, Snider GL, Franzblau C. The fate of newly synthesized lung collagen after endotracheal administration of C-proline to hamsters. Am Rev Respir Dis. 1978 Feb; 117(2):281-7. PMID: 637411.
    View in: PubMed
  89. Snider GL, Celli BR, Goldstein RH, O'Brien JJ, Lucey EC. Chronic interstitial pulmonary fibrosis produced in hamsters by endotracheal bleomycin. Lung volumes, volume-pressure relations, carbon monoxide uptake, and arterial blood gas studied. Am Rev Respir Dis. 1978 Feb; 117(2):289-97. PMID: 76453.
    View in: PubMed
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