Ivana Delalle | Profiles RNS

Ivana Delalle, MD, PhD

Professor

Boston University Chobanian & Avedisian School of Medicine

Pathology & Laboratory Medicine

Anatomic Pathology

MD, University of Zagreb
PhD, University of Zagreb

Websites

	Researchers @ Brown
	Department of Medicine Faculty
	Boston Medical Center Provider Profile
	LinkedIn

ORCID : 0000-0002-1873-3064

Dr. Delalle is a Professor of Pathology and Laboratory Medicine at the Warren Alpert School of Medicine at Brown University. She is a Director of Neuropathology Service at Lifespan Academic Medical Center. Dr. Delalle attended the Zagreb University School of Medicine, Zagreb, Croatia, where she received her MD in 1988 and, in 1992, her PhD in the Developmental Neuroanatomy Laboratory headed by Professor Ivica Kostovic, a pioneer in the understanding of transient layers in the developing human cortex. Dr. Delalle subsequently joined Developmental Neurobiology Laboratory headed by Professor Verne Caviness at Massachusetts General Hospital (MGH) in Boston where she elucidated the expression of cell cycle regulators in relation to the cortical development. After completing her Research Fellowship in Neurology at Harvard Medical School in 1997, Dr. Delalle pursued further postgraduate training as a resident in Anatomic Pathology and Neuropathology in the Department of Pathology at MGH. She became board certified by the American Board of Pathology in Anatomic Pathology and Neuropathology in 2001. Before joining Lifespan Academic Medical Center and Brown University, Dr. Delalle worked in the teaching hospitals of Harvard Medical School and Chobanian and Avedisian School of Medicine as a scientist investigating neurodegenerative and neuropsychiatric diseases, as a neuropathologist with expertise in neurooncology in the clinical arena, and as a teacher and mentor committed to the education of medical students, residents, and neuropathology fellows.

Associate Professor
Boston University Chobanian & Avedisian School of Medicine
Neurology

Professor
Brown University
Pathology & Laboratory Medicine

Member
Boston University
Evans Center for Interdisciplinary Biomedical Research

BU Research
NIH RePORTER Research

Long Non-coding RNAs as Therapeutic Targets and Biomarkers of Alzheimer's Disease and Related Dementias
09/01/2024 - 05/31/2029 (Multi-PI)
PI: Ivana Delalle, MD, PhD
NIH/National Institute on Aging
1R01AG084624-01

Investigation of impaired neural stem cell activation in Alzheimer's Disease
08/01/2023 - 03/31/2027 (Subcontract PI)
Buck Institute for Research on Aging NIH NIA
7R01AG076933-03

MicroRNAs as Diagnostic and Prognostic Biomarker of Alzheimer's Disease
11/01/2023 - 08/31/2025 (PI)
NIH/National Institute on Aging
7RF1AG078299-02

Epigenetic of Alzheimer's Disease
09/27/2011 - 08/31/2014 (Subcontract PI)
Massachusetts Institute of Technology NIH NINDS
5R01NS078839-02

Analysis of Retinal Degeneration in Drosophila
08/03/2001 - 05/31/2007 (PI)
NIH/National Eye Institute
7 K08 EY13639 04

Title

Yr	Title	Project-Sub Proj	Pubs
2024	Long Non-coding RNAs as Therapeutic Targets and Biomarkers of Alzheimer's Disease and Related Dementias	1R01AG084624-01
2022	MicroRNAs as Diagnostic and Prognostic Biomarker of Alzheimer's Disease	7RF1AG078299-02
2011	Exosomal and cell-class specific miRNA profiles in bipolar disorder and schizophr	5R21MH086079-02	2
2010	Exosomal and cell-class specific miRNA profiles in bipolar disorder and schizophr	1R21MH086079-01A2	2
2005	ANALYSIS OF RETINAL DEGENERATION IN DROSOPHILA	7K08EY013639-05	2
2004	ANALYSIS OF RETINAL DEGENERATION IN DROSOPHILA	5K08EY013639-04	2
2003	ANALYSIS OF RETINAL DEGENERATION IN DROSOPHILA	5K08EY013639-03	2
2002	ANALYSIS OF RETINAL DEGENERATION IN DROSOPHILA	5K08EY013639-02	2
2001	ANALYSIS OF RETINAL DEGENERATION IN DROSOPHILA	1K08EY013639-01	2

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Fischer A, Nho K, Saykin AJ, Delalle I. Response to the Letter, "Circulating small RNAs shed light on dementia risk," by Anthony S. Zannas. Alzheimers Dement. 2025 Jan 27. PMID: 39868847

Liu S, Park T, Krüger DM, Pena-Centeno T, Burkhardt S, Schutz AL, Huang YN, Rosewood T, Chaudhuri S, Cho M, Risacher SL, Wan Y, Shaw LM, Sananbenesi F, Brodsky AS, Lin H, Krunic A, Blusztajn JK, Saykin AJ, Delalle I, Fischer A, Nho K. Plasma miRNAs across the Alzheimer's disease continuum: Relationship to central biomarkers. Alzheimers Dement. 2024 Nov; 20(11):7698-7714.View Related Profiles.

Lin, Honghuang
Delalle, Ivana
Blusztajn, Jan

PMID: 39291737; PMCID: PMC11567826; DOI: 10.1002/alz.14230;

Krüger DM, Pena-Centeno T, Liu S, Park T, Kaurani L, Pradhan R, Huang YN, Risacher SL, Burkhardt S, Schütz AL, Wan Y, Shaw LM, Brodsky AS, DeStefano AL, Lin H, Schroeder R, Krunic A, Hempel N, Sananbenesi F, Blusztajn JK, Saykin AJ, Delalle I, Nho K, Fischer A. The plasma miRNAome in ADNI: Signatures to aid the detection of at-risk individuals. Alzheimers Dement. 2024 Nov; 20(11):7479-7494.View Related Profiles.

DeStefano, Anita
Lin, Honghuang
Delalle, Ivana
Blusztajn, Jan

PMID: 39291752; PMCID: PMC11567822; DOI: 10.1002/alz.14157;

Schröder S, Fuchs U, Gisa V, Pena T, Krüger DM, Hempel N, Burkhardt S, Salinas G, Schütz AL, Delalle I, Sananbenesi F, Fischer A. PRDM16-DT is a novel lncRNA that regulates astrocyte function in Alzheimer's disease. Acta Neuropathol. 2024 Aug 29; 148(1):32. PMID: 39207536; PMCID: PMC11362476; DOI: 10.1007/s00401-024-02787-x;

Schröder S, Fuchs U, Gisa V, Pena T, Krüger DM, Hempel N, Burkhardt S, Salinas G, Schütz AL, Delalle I, Sananbenesi F, Fischer A. PRDM16-DT: A Brain and Astrocyte-Specific lncRNA Implicated in Alzheimer's Disease. bioRxiv. 2024 Jul 01. PMID: 39005272; PMCID: PMC11244882; DOI: 10.1101/2024.06.27.600964;

Kaurani L, Islam MR, Heilbronner U, Krüger DM, Zhou J, Methi A, Strauss J, Pradhan R, Schröder S, Burkhardt S, Schuetz AL, Pena T, Erlebach L, Bühler A, Budde M, Senner F, Kohshour MO, Schulte EC, Schmauß M, Reininghaus EZ, Juckel G, Kronenberg-Versteeg D, Delalle I, Odoardi F, Flügel A, Schulze TG, Falkai P, Sananbenesi F, Fischer A. Regulation of Zbp1 by miR-99b-5p in microglia controls the development of schizophrenia-like symptoms in mice. EMBO J. 2024 Apr; 43(8):1420-1444. PMID: 38528182; PMCID: PMC11021462; DOI: 10.1038/s44318-024-00067-8;

Alexander A, Alvarez VE, Huber BR, Alosco ML, Mez J, Tripodis Y, Nicks R, Katz DI, Dwyer B, Daneshvar DH, Martin B, Palmisano J, Goldstein LE, Crary JF, Nowinski C, Cantu RC, Kowall NW, Stern RA, Delalle I, McKee AC, Stein TD. Cortical-sparing chronic traumatic encephalopathy (CSCTE): a distinct subtype of CTE. Acta Neuropathol. 2024 Feb 26; 147(1):45.View Related Profiles.

McKee, Ann
Huber, Bertrand
Dwyer, Brigid
Nowinski, Christopher
Daneshvar, Daniel
Katz, Douglas
Delalle, Ivana
Mez, Jesse
Goldstein, Lee
Alosco, Michael
Kowall, Neil
Stern, Robert
Stein, Thor
Alvarez, Victor
Tripodis, Yorghos

PMID: 38407651; PMCID: PMC11348287; DOI: 10.1007/s00401-024-02690-5;

Castro-Hernández R, Berulava T, Metelova M, Epple R, Peña Centeno T, Richter J, Kaurani L, Pradhan R, Sakib MS, Burkhardt S, Ninov M, Bohnsack KE, Bohnsack MT, Delalle I, Fischer A. Conserved reduction of m6A RNA modifications during aging and neurodegeneration is linked to changes in synaptic transcripts. Proc Natl Acad Sci U S A. 2023 Feb 28; 120(9):e2204933120. PMID: 36812208; PMCID: PMC9992849; DOI: 10.1073/pnas.2204933120;

Tubre T, Hacking S, Alexander A, Brickman A, Delalle I, Elinzano H, Donahue JE. Prostate-Specific Membrane Antigen Expression in Meningioma: A Promising Theranostic Target. J Neuropathol Exp Neurol. 2022 Nov 16; 81(12):1008-1017. PMID: 36179256; PMCID: PMC9677239; DOI: 10.1093/jnen/nlac089;

Oraki Kohshour M, Papiol S, Delalle I, Rossner MJ, Schulze TG. Extracellular vesicle approach to major psychiatric disorders. Eur Arch Psychiatry Clin Neurosci. 2023 Sep; 273(6):1279-1293. PMID: 36302978; PMCID: PMC10450008; DOI: 10.1007/s00406-022-01497-3;

Showing 10 of 56 results. Show More

Schulze TG, Delalle I. Engineered extracellular vesicles and their promising therapeutic potential in neuropsychiatric disorders. Eur Neuropsychopharmacol. 2022 Oct; 63:14-16. PMID: 35914375

Delalle I. MicroRNAs as Candidates for Bipolar Disorder Biomarkers. Psychiatr Danub. 2021 Spring-Summer; 33(Suppl 4):451-455. PMID: 34718264

Kanach C, Blusztajn JK, Fischer A, Delalle I. MicroRNAs as Candidate Biomarkers for Alzheimer's Disease. Noncoding RNA. 2021 Feb 01; 7(1).View Related Profiles.

Delalle, Ivana
Blusztajn, Jan

PMID: 33535543; PMCID: PMC7930943; DOI: 10.3390/ncrna7010008;

Anderson KE, Bellio TA, Aniskovich E, Adams SL, Blusztajn JK, Delalle I. The Expression of Activin Receptor-Like Kinase 1 (ACVRL1/ALK1) in Hippocampal Arterioles Declines During Progression of Alzheimer's Disease. Cereb Cortex Commun. 2020; 1(1):tgaa031.View Related Profiles.

Delalle, Ivana
Blusztajn, Jan
Bellio, Thomas

PMID: 32974611; PMCID: PMC7497413; DOI: 10.1093/texcom/tgaa031;

Jain G, Stuendl A, Rao P, Berulava T, Pena Centeno T, Kaurani L, Burkhardt S, Delalle I, Kornhuber J, Hüll M, Maier W, Peters O, Esselmann H, Schulte C, Deuschle C, Synofzik M, Wiltfang J, Mollenhauer B, Maetzler W, Schneider A, Fischer A. A combined miRNA-piRNA signature to detect Alzheimer's disease. Transl Psychiatry. 2019 10 07; 9(1):250. PMID: 31591382; PMCID: PMC6779890; DOI: 10.1038/s41398-019-0579-2;

Gail Canter R, Huang WC, Choi H, Wang J, Ashley Watson L, Yao CG, Abdurrob F, Bousleiman SM, Young JZ, Bennett DA, Delalle I, Chung K, Tsai LH. 3D mapping reveals network-specific amyloid progression and subcortical susceptibility in mice. Commun Biol. 2019 Oct 04; 2(1):360. PMID: 31925184

Cagney DN, Miller MB, Dubuc A, Delalle I, Ligon AH, Chukwueke U, Al-Mefty O, Aizer A, Ligon K, Wen P. Clinical Importance of CDKN2A Loss and Monosomy 10 in Pilocytic Astrocytoma. Cureus. 2019 May 23; 11(5):e4726. PMID: 31355086; PMCID: PMC6649926; DOI: 10.7759/cureus.4726;

Conner SC, Benayoun L, Himali JJ, Adams SL, Yang Q, DeCarli C, Blusztajn JK, Beiser A, Seshadri S, Delalle I. Methionine Sulfoxide Reductase-B3 Risk Allele Implicated in Alzheimer's Disease Associates with Increased Odds for Brain Infarcts. J Alzheimers Dis. 2019; 68(1):357-365.View Related Profiles.

Beiser, Alexa
Delalle, Ivana
Blusztajn, Jan
Himali, Jayandra
Yang, Qiong
Seshadri, Sudha

PMID: 30775993; PMCID: PMC6481535; DOI: 10.3233/JAD-180977;

Adams SL, Benayoun L, Tilton K, Mellott TJ, Seshadri S, Blusztajn JK, Delalle I. Immunohistochemical Analysis of Activin Receptor-Like Kinase 1 (ACVRL1/ALK1) Expression in the Rat and Human Hippocampus: Decline in CA3 During Progression of Alzheimer's Disease. J Alzheimers Dis. 2018; 63(4):1433-1443.View Related Profiles.

Delalle, Ivana
Blusztajn, Jan
Seshadri, Sudha
Mellott, Tiffany

PMID: 29843236; PMCID: PMC5988976; DOI: 10.3233/JAD-171065;

Agís-Balboa RC, Pinheiro PS, Rebola N, Kerimoglu C, Benito E, Gertig M, Bahari-Javan S, Jain G, Burkhardt S, Delalle I, Jatzko A, Dettenhofer M, Zunszain PA, Schmitt A, Falkai P, Pape JC, Binder EB, Mulle C, Fischer A, Sananbenesi F. Formin 2 links neuropsychiatric phenotypes at young age to an increased risk for dementia. EMBO J. 2017 Oct 02; 36(19):2815-2828. PMID: 28768717; PMCID: PMC5623844; DOI: 10.15252/embj.201796821;

Ramkissoon SH, Bandopadhayay P, Hwang J, Ramkissoon LA, Greenwald NF, Schumacher SE, O'Rourke R, Pinches N, Ho P, Malkin H, Sinai C, Filbin M, Plant A, Bi WL, Chang MS, Yang E, Wright KD, Manley PE, Ducar M, Alexandrescu S, Lidov H, Delalle I, Goumnerova LC, Church AJ, Janeway KA, Harris MH, MacConaill LE, Folkerth RD, Lindeman NI, Stiles CD, Kieran MW, Ligon AH, Santagata S, Dubuc AM, Chi SN, Beroukhim R, Ligon KL. Clinical targeted exome-based sequencing in combination with genome-wide copy number profiling: precision medicine analysis of 203 pediatric brain tumors. Neuro Oncol. 2017 Jul 01; 19(7):986-996. PMID: 28104717; PMCID: PMC5570190; DOI: 10.1093/neuonc/now294;

Bahari-Javan S, Varbanov H, Halder R, Benito E, Kaurani L, Burkhardt S, Anderson-Schmidt H, Anghelescu I, Budde M, Stilling RM, Costa J, Medina J, Dietrich DE, Figge C, Folkerts H, Gade K, Heilbronner U, Koller M, Konrad C, Nussbeck SY, Scherk H, Spitzer C, Stierl S, Stöckel J, Thiel A, von Hagen M, Zimmermann J, Zitzelsberger A, Schulz S, Schmitt A, Delalle I, Falkai P, Schulze TG, Dityatev A, Sananbenesi F, Fischer A. HDAC1 links early life stress to schizophrenia-like phenotypes. Proc Natl Acad Sci U S A. 2017 06 06; 114(23):E4686-E4694. PMID: 28533418; PMCID: PMC5468618; DOI: 10.1073/pnas.1613842114;

Choi JL, Kao PF, Itriago E, Zhan Y, Kozubek JA, Hoss AG, Banigan MG, Vanderburg CR, Rezvani AH, Latourelle JC, Cabral H, Delalle I. miR-149 and miR-29c as candidates for bipolar disorder biomarkers. Am J Med Genet B Neuropsychiatr Genet. 2017 Apr; 174(3):315-323.View Related Profiles.

Hoss, Andrew
Cabral, Howard
Delalle, Ivana
Latourelle, Jeanne

PMID: 28190298; DOI: 10.1002/ajmg.b.32518;

Adams SL, Benayoun L, Tilton K, Chavez OR, Himali JJ, Blusztajn JK, Seshadri S, Delalle I. Methionine Sulfoxide Reductase-B3 (MsrB3) Protein Associates with Synaptic Vesicles and its Expression Changes in the Hippocampi of Alzheimer's Disease Patients. J Alzheimers Dis. 2017; 60(1):43-56.View Related Profiles.

Delalle, Ivana
Blusztajn, Jan
Himali, Jayandra
Chavez, Olivia
Seshadri, Sudha

PMID: 28777754; PMCID: PMC5922439; DOI: 10.3233/JAD-170459;

Adams SL, Tilton K, Kozubek JA, Seshadri S, Delalle I. Subcellular Changes in Bridging Integrator 1 Protein Expression in the Cerebral Cortex During the Progression of Alzheimer Disease Pathology. J Neuropathol Exp Neurol. 2016 Aug; 75(8):779-790.View Related Profiles.

Delalle, Ivana
Seshadri, Sudha

PMID: 27346750; PMCID: PMC6281026; DOI: 10.1093/jnen/nlw056;

Šimic G, Babic Leko M, Wray S, Harrington CR, Delalle I, Jovanov-Miloševic N, Bažadona D, Buée L, de Silva R, Di Giovanni G, Wischik CM, Hof PR. Monoaminergic neuropathology in Alzheimer's disease. Prog Neurobiol. 2017 Apr; 151:101-138. PMID: 27084356; PMCID: PMC5061605; DOI: 10.1016/j.pneurobio.2016.04.001;

Olmos-Serrano JL, Kang HJ, Tyler WA, Silbereis JC, Cheng F, Zhu Y, Pletikos M, Jankovic-Rapan L, Cramer NP, Galdzicki Z, Goodliffe J, Peters A, Sethares C, Delalle I, Golden JA, Haydar TF, Sestan N. Down Syndrome Developmental Brain Transcriptome Reveals Defective Oligodendrocyte Differentiation and Myelination. Neuron. 2016 Mar 16; 89(6):1208-22.View Related Profiles.

Peters, Alan
Delalle, Ivana
Goodliffe, Joseph
Pletikos, Mihovil
Haydar, Tarik
Tyler, William

PMID: 26924435; PMCID: PMC4795969; DOI: 10.1016/j.neuron.2016.01.042;

Šimic G, Babic Leko M, Wray S, Harrington C, Delalle I, Jovanov-Miloševic N, Bažadona D, Buée L, de Silva R, Di Giovanni G, Wischik C, Hof PR. Tau Protein Hyperphosphorylation and Aggregation in Alzheimer's Disease and Other Tauopathies, and Possible Neuroprotective Strategies. Biomolecules. 2016 Jan 06; 6(1):6. PMID: 26751493; PMCID: PMC4808800; DOI: 10.3390/biom6010006;

Seo J, Giusti-Rodríguez P, Zhou Y, Rudenko A, Cho S, Ota KT, Park C, Patzke H, Madabhushi R, Pan L, Mungenast AE, Guan JS, Delalle I, Tsai LH. Activity-dependent p25 generation regulates synaptic plasticity and Aß-induced cognitive impairment. Cell. 2014 Apr 10; 157(2):486-98. PMID: 24725413; PMCID: PMC4327772; DOI: 10.1016/j.cell.2014.01.065;

Qin B, Tabbara AK, Delalle I, Holsapple J, Hohler A. An enigmatic brainstem posterior fossa ganglioglioma in an adult. Int J Neurosci. 2014 Sep; 124(9):704-6.View Related Profiles.

Hohler, Anna
Delalle, Ivana
Holsapple, James

PMID: 24405263; DOI: 10.3109/00207454.2013.877901;

Berkowitz AL, Sheu SH, Rose MF, Delalle I, Folkerth RD. Bilirubin labeling of borderzone and anterior cerebral artery territory infarction. Neurology. 2013 Oct 1; 81(14):1272-3. PMID: 24081962; PMCID: PMC3795605; DOI: 10.1212/WNL.0b013e3182a6cbb2;

Agbemenyah HY, Agis-Balboa RC, Burkhardt S, Delalle I, Fischer A. Insulin growth factor binding protein 7 is a novel target to treat dementia. Neurobiol Dis. 2014 Feb; 62:135-43. PMID: 24075854; DOI: 10.1016/j.nbd.2013.09.011;

Thaci B, Burns JD, Delalle I, Vu T, Davies KG. Intractable hiccups resolved after resection of a cavernous malformation of the medulla oblongata. Clin Neurol Neurosurg. 2013 Oct; 115(10):2247-50.View Related Profiles.

Delalle, Ivana
Burns, Joseph
Davies, Keith
Vu, Thai

PMID: 23932467; DOI: 10.1016/j.clineuro.2013.07.005;

Banigan MG, Kao PF, Kozubek JA, Winslow AR, Medina J, Costa J, Schmitt A, Schneider A, Cabral H, Cagsal-Getkin O, Vanderburg CR, Delalle I. Differential expression of exosomal microRNAs in prefrontal cortices of schizophrenia and bipolar disorder patients. PLoS One. 2013; 8(1):e48814.View Related Profiles.

Cabral, Howard
Delalle, Ivana

PMID: 23382797; PMCID: PMC3559697; DOI: 10.1371/journal.pone.0048814;

Kao PF, Banigan MG, Vanderburg CR, McKee AC, Polgar PR, Seshadri S, Delalle I. Increased expression of TrkB and Capzb2 accompanies preserved cognitive status in early Alzheimer disease pathology. J Neuropathol Exp Neurol. 2012 Jul; 71(7):654-64.View Related Profiles.

McKee, Ann
Delalle, Ivana
Polgar, Peter
Seshadri, Sudha

PMID: 22710966; PMCID: PMC3398703; DOI: 10.1097/NEN.0b013e31825d06b7;

Gräff J, Rei D, Guan JS, Wang WY, Seo J, Hennig KM, Nieland TJ, Fass DM, Kao PF, Kahn M, Su SC, Samiei A, Joseph N, Haggarty SJ, Delalle I, Tsai LH. An epigenetic blockade of cognitive functions in the neurodegenerating brain. Nature. 2012 Mar 8; 483(7388):222-6. PMID: 22388814; PMCID: PMC3498952; DOI: 10.1038/nature10849;

Stapleton CJ, Walcott BP, Kahle KT, Codd PJ, Nahed BV, Chen L, Robison NJ, Delalle I, Goumnerova LC, Jackson EM. Diffuse central neurocytoma with craniospinal dissemination. J Clin Neurosci. 2012 Jan; 19(1):163-6. PMID: 22088950; DOI: 10.1016/j.jocn.2011.07.016;

Zovoilis A, Agbemenyah HY, Agis-Balboa RC, Stilling RM, Edbauer D, Rao P, Farinelli L, Delalle I, Schmitt A, Falkai P, Bahari-Javan S, Burkhardt S, Sananbenesi F, Fischer A. microRNA-34c is a novel target to treat dementias. EMBO J. 2011 Oct 19; 30(20):4299-308. PMID: 21946562; PMCID: PMC3199394; DOI: 10.1038/emboj.2011.327;

Toshkezi G, Edalat F, O'Hara C, Delalle I, Chin LS. Primary intramedullary histiocytic sarcoma. World Neurosurg. 2010 Oct-Nov; 74(4-5):523-7.View Related Profiles.

O'Hara, Carl
Delalle, Ivana

PMID: 21492606; DOI: 10.1016/j.wneu.2010.07.002;

Kao PF, Davis DA, Banigan MG, Vanderburg CR, Seshadri S, Delalle I. Modulators of cytoskeletal reorganization in CA1 hippocampal neurons show increased expression in patients at mid-stage Alzheimer's disease. PLoS One. 2010; 5(10):e13337.View Related Profiles.

Delalle, Ivana
Seshadri, Sudha

PMID: 20967212; PMCID: PMC2954170; DOI: 10.1371/journal.pone.0013337;

Vanderburg CR, Davis DA, Diamond RE, Kao PF, Delalle I. Capzb2 PROTEIN EXPRESSION IN THE BRAINS OF PATIENTS DIAGNOSED WITH ALZHEIMER'S DISEASE AND HUNTINGTON'S DISEASE. Transl Neurosci. 2010 Mar; 1(1):55-58. PMID: 29662700; PMCID: PMC5899514; DOI: 10.2478/v10134-010-0008-9;

Davis DA, Wilson MH, Giraud J, Xie Z, Tseng HC, England C, Herscovitz H, Tsai LH, Delalle I. Capzb2 interacts with beta-tubulin to regulate growth cone morphology and neurite outgrowth. PLoS Biol. 2009 Oct; 7(10):e1000208.View Related Profiles.

Herscovitz, Haya
Delalle, Ivana
Xie, Zhigang

PMID: 19806181; PMCID: PMC2748697; DOI: 10.1371/journal.pbio.1000208;

Saad A, Tuli S, Ali EN, Houtchens M, Delalle I, Kesari S. Pilocytic astrocytoma of the spinal cord in an adult. J Neurooncol. 2008 Jun; 88(2):189-91. PMID: 18340405; DOI: 10.1007/s11060-008-9547-z;

Saad AG, Jayarao M, Chin LS, Delalle I. Ganglioglioma associated with cerebral cortical dysplasia: an unusual case with extensive leptomeningeal involvement. Pediatr Dev Pathol. 2008 Nov-Dec; 11(6):474-8. PMID: 18338935; DOI: 10.2350/07-10-0360.1;

Kim D, Nguyen MD, Dobbin MM, Fischer A, Sananbenesi F, Rodgers JT, Delalle I, Baur JA, Sui G, Armour SM, Puigserver P, Sinclair DA, Tsai LH. SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis. EMBO J. 2007 Jul 11; 26(13):3169-79. PMID: 17581637; PMCID: PMC1914106; DOI: 10.1038/sj.emboj.7601758;

Delalle I, Pfleger CM, Buff E, Lueras P, Hariharan IK. Mutations in the Drosophila orthologs of the F-actin capping protein alpha- and beta-subunits cause actin accumulation and subsequent retinal degeneration. Genetics. 2005 Dec; 171(4):1757-65. PMID: 16143599; PMCID: PMC1456101; DOI: 10.1534/genetics.105.049213;

Alderson LM, Delalle I. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 10-2002. A 52-year-old woman with recurrent unsteadiness, slurred speech, and fatigue. N Engl J Med. 2002 Mar 28; 346(13):1009-15. PMID: 11919311

Brouns MR, Matheson SF, Hu KQ, Delalle I, Caviness VS, Silver J, Bronson RT, Settleman J. The adhesion signaling molecule p190 RhoGAP is required for morphogenetic processes in neural development. Development. 2000 Nov; 127(22):4891-903. PMID: 11044403

Delalle I, Takahashi T, Nowakowski RS, Tsai LH, Caviness VS. Cyclin E-p27 opposition and regulation of the G1 phase of the cell cycle in the murine neocortical PVE: a quantitative analysis of mRNA in situ hybridization. Cereb Cortex. 1999 Dec; 9(8):824-32. PMID: 10601001

Delalle I, Bhide PG, Caviness VS, Tsai LH. Temporal and spatial patterns of expression of p35, a regulatory subunit of cyclin-dependent kinase 5, in the nervous system of the mouse. J Neurocytol. 1997 May; 26(5):283-96. PMID: 9192293

Uylings HB, Delalle I. Morphology of neuropeptide Y-immunoreactive neurons and fibers in human prefrontal cortex during prenatal and postnatal development. J Comp Neurol. 1997 Mar 24; 379(4):523-40. PMID: 9067841

Delalle I, Evers P, Kostovic I, Uylings HB. Laminar distribution of neuropeptide Y-immunoreactive neurons in human prefrontal cortex during development. J Comp Neurol. 1997 Mar 24; 379(4):515-22. PMID: 9067840

Caviness VS, Takahashi T, Miyama S, Nowakowski RS, Delalle I. Regulation of normal proliferation in the developing cerebrum potential actions of trophic factors. Exp Neurol. 1996 Feb; 137(2):357-66. PMID: 8635552

Tsai LH, Delalle I, Caviness VS, Chae T, Harlow E. p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5. Nature. 1994 Sep 29; 371(6496):419-23. PMID: 8090221

Kostovic I, Judas M, Kostovic-Knezevic L, Simic G, Delalle I, Chudy D, Sajin B, Petanjek Z. Zagreb research collection of human brains for developmental neurobiologists and clinical neuroscientists. Int J Dev Biol. 1991 Sep; 35(3):215-30. PMID: 1687658

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 56 publications over 26 distinct years, with a maximum of 6 publications in 2024

Bar chart showing 56 publications over 26 distinct years, with a maximum of 6 publications in 2024

Year	Publications
1991	1
1994	1
1996	1
1997	3
1999	1
2000	1
2002	1
2005	1
2007	1
2008	2
2009	1
2010	2
2011	3
2012	2
2013	4
2014	2
2016	4
2017	5
2018	1
2019	5
2020	1
2021	2
2022	3
2023	1
2024	6
2025	1

Media Mentions

MicroRNAs Show Potential for Dementia Screening

Inside Precision Medicine 9/19/2024

New biomarkers offer hope for early detection and prevention of Alzheimer's

News Medical 9/18/2024

The microRNA Blood Test That Might Outsmart Alzheimer’s

SciTech Daily 9/18/2024

Breakthrough blood test could detect early stages of Alzheimer’s YEARS before symptoms show

The Sun 9/18/2024

In addition to these self-described keywords below, a list of MeSH based concepts is available here.

biomarkers
bipolar disorder
cytoskeleton
exosomal miRNAs
neurodegeneration
schizophrenia

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