Ivana Delalle, MD, PhD
Boston University Chobanian & Avedisian School of Medicine
Pathology & Laboratory Medicine
Anatomic Pathology

MD, University of Zagreb
PhD, University of Zagreb

Dr. Delalle is a Professor of Pathology and Laboratory Medicine at the Warren Alpert School of Medicine at Brown University. She is a Director of Neuropathology Service at Lifespan Academic Medical Center. Dr. Delalle attended the Zagreb University School of Medicine, Zagreb, Croatia, where she received her MD in 1988 and, in 1992, her PhD in the Developmental Neuroanatomy Laboratory headed by Professor Ivica Kostovic, a pioneer in the understanding of transient layers in the developing human cortex. Dr. Delalle subsequently joined Developmental Neurobiology Laboratory headed by Professor Verne Caviness at Massachusetts General Hospital (MGH) in Boston where she elucidated the expression of cell cycle regulators in relation to the cortical development. After completing her Research Fellowship in Neurology at Harvard Medical School in 1997, Dr. Delalle pursued further postgraduate training as a resident in Anatomic Pathology and Neuropathology in the Department of Pathology at MGH. She became board certified by the American Board of Pathology in Anatomic Pathology and Neuropathology in 2001. Before joining Lifespan Academic Medical Center and Brown University, Dr. Delalle worked in the teaching hospitals of Harvard Medical School and Chobanian and Avedisian School of Medicine as a scientist investigating neurodegenerative and neuropsychiatric diseases, as a neuropathologist with expertise in neurooncology in the clinical arena, and as a teacher and mentor committed to the education of medical students, residents, and neuropathology fellows.

Associate Professor
Boston University Chobanian & Avedisian School of Medicine

Brown University
Pathology & Laboratory Medicine

Boston University
Evans Center for Interdisciplinary Biomedical Research

MicroRNAs as Diagnostic and Prognostic Biomarker of Alzheimer's Disease
03/01/2024 - 08/31/2025 (PI)
NIH/National Institute on Aging

Epigenetic of Alzheimer's Disease
09/27/2011 - 08/31/2014 (Subcontract PI)
Massachusetts Institute of Technology NIH NINDS

Analysis of Retinal Degeneration in Drosophila
08/03/2001 - 05/31/2007 (PI)
NIH/National Eye Institute
7 K08 EY13639 04


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Kaurani L, Islam MR, Heilbronner U, Krüger DM, Zhou J, Methi A, Strauss J, Pradhan R, Schröder S, Burkhardt S, Schuetz AL, Pena T, Erlebach L, Bühler A, Budde M, Senner F, Kohshour MO, Schulte EC, Schmauß M, Reininghaus EZ, Juckel G, Kronenberg-Versteeg D, Delalle I, Odoardi F, Flügel A, Schulze TG, Falkai P, Sananbenesi F, Fischer A. Regulation of Zbp1 by miR-99b-5p in microglia controls the development of schizophrenia-like symptoms in mice. EMBO J. 2024 Apr; 43(8):1420-1444. PMID: 38528182; PMCID: PMC11021462; DOI: 10.1038/s44318-024-00067-8;
  2. Alexander A, Alvarez VE, Huber BR, Alosco ML, Mez J, Tripodis Y, Nicks R, Katz DI, Dwyer B, Daneshvar DH, Martin B, Palmisano J, Goldstein LE, Crary JF, Nowinski C, Cantu RC, Kowall NW, Stern RA, Delalle I, McKee AC, Stein TD. Cortical-sparing chronic traumatic encephalopathy (CSCTE): a distinct subtype of CTE. Acta Neuropathol. 2024 Feb 26; 147(1):45.View Related Profiles. PMID: 38407651
  3. Castro-Hernández R, Berulava T, Metelova M, Epple R, Peña Centeno T, Richter J, Kaurani L, Pradhan R, Sakib MS, Burkhardt S, Ninov M, Bohnsack KE, Bohnsack MT, Delalle I, Fischer A. Conserved reduction of m6A RNA modifications during aging and neurodegeneration is linked to changes in synaptic transcripts. Proc Natl Acad Sci U S A. 2023 Feb 28; 120(9):e2204933120. PMID: 36812208; PMCID: PMC9992849; DOI: 10.1073/pnas.2204933120;
  4. Tubre T, Hacking S, Alexander A, Brickman A, Delalle I, Elinzano H, Donahue JE. Prostate-Specific Membrane Antigen Expression in Meningioma: A Promising Theranostic Target. J Neuropathol Exp Neurol. 2022 Nov 16; 81(12):1008-1017. PMID: 36179256; PMCID: PMC9677239; DOI: 10.1093/jnen/nlac089;
  5. Oraki Kohshour M, Papiol S, Delalle I, Rossner MJ, Schulze TG. Extracellular vesicle approach to major psychiatric disorders. Eur Arch Psychiatry Clin Neurosci. 2023 Sep; 273(6):1279-1293. PMID: 36302978; PMCID: PMC10450008; DOI: 10.1007/s00406-022-01497-3;
  6. Schulze TG, Delalle I. Engineered extracellular vesicles and their promising therapeutic potential in neuropsychiatric disorders. Eur Neuropsychopharmacol. 2022 Oct; 63:14-16. PMID: 35914375
  7. Delalle I. MicroRNAs as Candidates for Bipolar Disorder Biomarkers. Psychiatr Danub. 2021 Spring-Summer; 33(Suppl 4):451-455. PMID: 34718264
  8. Kanach C, Blusztajn JK, Fischer A, Delalle I. MicroRNAs as Candidate Biomarkers for Alzheimer's Disease. Noncoding RNA. 2021 Feb 01; 7(1).View Related Profiles. PMID: 33535543; PMCID: PMC7930943; DOI: 10.3390/ncrna7010008;
  9. Anderson KE, Bellio TA, Aniskovich E, Adams SL, Blusztajn JK, Delalle I. The Expression of Activin Receptor-Like Kinase 1 (ACVRL1/ALK1) in Hippocampal Arterioles Declines During Progression of Alzheimer's Disease. Cereb Cortex Commun. 2020; 1(1):tgaa031.View Related Profiles. PMID: 32974611; PMCID: PMC7497413; DOI: 10.1093/texcom/tgaa031;
  10. Jain G, Stuendl A, Rao P, Berulava T, Pena Centeno T, Kaurani L, Burkhardt S, Delalle I, Kornhuber J, Hüll M, Maier W, Peters O, Esselmann H, Schulte C, Deuschle C, Synofzik M, Wiltfang J, Mollenhauer B, Maetzler W, Schneider A, Fischer A. A combined miRNA-piRNA signature to detect Alzheimer's disease. Transl Psychiatry. 2019 10 07; 9(1):250. PMID: 31591382; PMCID: PMC6779890; DOI: 10.1038/s41398-019-0579-2;
Showing 10 of 51 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 51 publications over 25 distinct years, with a maximum of 5 publications in 2017 and 2019


In addition to these self-described keywords below, a list of MeSH based concepts is available here.

bipolar disorder
exosomal miRNAs
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