James Holsapple | Profiles RNS

James W. Holsapple, MD

Chair

Boston University Chobanian & Avedisian School of Medicine

Neurosurgery

MD, University of Kansas
BA, Drake University

Websites

	BMC
	BUSM
	GMS

ORCID : 0000-0003-0419-4474

James Holsapple, MD, has been an associate professor of neurosurgery and pediatrics at BMC/BUSM since 2009. Holsapple received his undergraduate degree from Drake University, Magna Cum Laude, and his MD from University of Kansas School of Medicine. He completed an internal medicine internship at St. Luke’s Hospital, Kansas City, Missouri and a general surgery internship and neurological surgery residency at Upstate Medical University (SUNY), where he was also a NRSA Research Fellow in the Departments of Neurological Surgery and Physiology. He then joined the faculty and was promoted to Associate Professor of Neurological Surgery and Pediatrics.

A resident of South Boston, Holsapple is a member of the New England Neurological Society, the Congress of Neurological Surgeons and the American Association of Neurological Surgeons. The author of numerous papers, peer-reviewed articles, chapters and case reports, his research interests include primate visual and motor processing, human brain tumor management and biology. Holsapple’s clinical interests include adult intracranial tumors, vascular surgery and pediatric neurosurgery.

Associate Professor
Boston University Chobanian & Avedisian School of Medicine
Neurosurgery

BMC Research
NIH RePORTER Research

Enhancing Diversity in the Summer Program in Neuroscience at Boston University
12/09/2023 - 11/30/2028 (Multi-PI)
PI: James W. Holsapple, MD
Trustees of Boston University, BUMC NIH NINDS
1R25NS125607-01A1

Noninvasive intracranial Pressure Estimation-Towards a Fully Noninvasive Bedside Monitoring Device
09/01/2015 - 07/31/2023 (Subcontract PI)
PI: James W. Holsapple, MD
Massachusetts Institute of Technology / MIT Philips Healthcare

CLEAR IVH III - Clot Lysis
07/01/2009 - 06/30/2012 (PI)
Johns Hopkins University NIH-NINDS

Title

Yr	Title	Project-Sub Proj	Pubs
2024	Enhancing Diversity in the Summer Program in Neuroscience at Boston University	1R25NS125607-01A1
1989	CORTICAL &THALAMIC INPUTS TO CINGULATE MOTOR AREA	5F32NS008439-02	2

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Jaishankar R, Teichmann D, Hayward A, Holsapple JW, Heldt T. Open cranium model for the study of cerebrovascular dynamics in intracranial hypertension. J Neurosci Methods. 2024 Sep; 409:110196. PMID: 38880344

Urbach H, Sileo N, Lerma S, Nguyen K, Sosa Soto G, Nielsen M, Heiderich A, Holsapple J, Vuppula S, Campbell JI. Ceftaroline for Central Nervous System Infections: Case Report of a Young Infant, and Scoping Review. Pediatr Infect Dis J. 2024 Jul 01; 43(7):663-668.View Related Profiles.

Heiderich, Amy
Holsapple, James
Campbell, Jeffrey
Nielsen, Marisa
Vuppula, Sharon

PMID: 38451889

Rizzo R, Wang JWJL, DePold Hohler A, Holsapple JW, Vaou OE, Ivanov PC. Dynamic networks of cortico-muscular interactions in sleep and neurodegenerative disorders. Front Netw Physiol. 2023; 3:1168677.View Related Profiles.

Holsapple, James
Vaou, Okeanis

PMID: 37744179; PMCID: PMC10512188; DOI: 10.3389/fnetp.2023.1168677;

Ravina K, Yang N, Brocoum S, Pasco-Anderson J, Walker RL, Khan M, Cabodi M, Holsapple J. Conical drill bit for optimized external ventricular drain placement: a proof-of-concept study. J Neurosurg. 2023 Sep 01; 139(3):881-891.View Related Profiles.

Holsapple, James
Cabodi, Mario

PMID: 36790016

Lee S, Kwok N, Holsapple J, Heldt T, Bourouiba L. Enhanced wall shear stress prevents obstruction by astrocytes in ventricular catheters. J R Soc Interface. 2020 07; 17(168):20190884. PMID: 32603649; PMCID: PMC7423414; DOI: 10.1098/rsif.2019.0884;

Haider G, Omofoye OA, Holsapple JW. Intracranial Hypertension Following Gunshot Wound to the Torcula: Case Report and Literature Review. World Neurosurg. 2020 05; 137:94-97.View Related Profiles.

Haider, Ghani
Holsapple, James

PMID: 32006734

Jaishankar R, Fanelli A, Filippidis A, Vu T, Holsapple J, Heldt T. A Spectral Approach to Model-Based Noninvasive Intracranial Pressure Estimation. IEEE J Biomed Health Inform. 2020 08; 24(8):2398-2406.View Related Profiles.

Filippidis, Aristotelis
Holsapple, James

PMID: 31880569; PMCID: PMC10615348; DOI: 10.1109/JBHI.2019.2961403;

Jaishankar R, Fanelli A, Filippidis A, Vu T, Holsapple J, Heldt T. A Frequency-domain Approach to Noninvasive Intracranial Pressure Estimation. Conf Proc IEEE Eng Med Biol Soc. 2019 07; 2019:5055-5058.View Related Profiles.

Filippidis, Aristotelis
Holsapple, James

PMID: 31946995

Mackel CE, Devaiah A, Holsapple J, Moore JM. Neural Crest Cell Failure as Embryogenesis for Fusiform Aneurysm of the Anterior Communicating Artery: Case Report and Review of the Literature. World Neurosurg. 2019 Sep; 129:232-236.View Related Profiles.

Devaiah, Anand
Holsapple, James
Moore, Justin

PMID: 31203061

Fanelli A, Jaishankar R, Filippidis A, Holsapple J, Heldt T. A Waveform Archiving System for the GE Solar 8000i Bedside Monitor. Acta Neurochir Suppl. 2018; 126:173-177.View Related Profiles.

Filippidis, Aristotelis
Holsapple, James

PMID: 29492556

Showing 10 of 30 results. Show More

Filippidis AS, Conroy TJ, Maragkos GA, Holsapple JW, Davies KG. Intraocular Silicone Oil Migration into the Ventricles Resembling Intraventricular Hemorrhage: Case Report and Review of the Literature. World Neurosurg. 2017 Jun; 102:695.e7-695.e10.View Related Profiles.

Filippidis, Aristotelis
Holsapple, James
Davies, Keith

PMID: 28385656; DOI: 10.1016/j.wneu.2017.03.131;

Mian AZ, Edasery D, Sakai O, Mustafa Qureshi M, Holsapple J, Nguyen T. Radiological imaging features of the basal ganglia that may predict progression to hemicraniectomy in large territory middle cerebral artery infarct. Neuroradiology. 2017 May; 59(5):477-484.View Related Profiles.

Mian, Asim
Holsapple, James
Qureshi, Muhammad
Sakai, Osamu
Nguyen, Thanh

PMID: 28353064; DOI: 10.1007/s00234-017-1823-1;

Stern RA, Seichepine D, Tschoe C, Fritts NG, Alosco ML, Berkowitz O, Burke P, Howland J, Olshaker J, Cantu RC, Baugh CM, Holsapple JW. Concussion Care Practices and Utilization of Evidence-Based Guidelines in the Evaluation and Management of Concussion: A Survey of New England Emergency Departments. J Neurotrauma. 2017 Feb 15; 34(4):861-868.View Related Profiles.

Seichepine, Daniel
Holsapple, James
Howland, Jonathan
Olshaker, Jonathan
Alosco, Michael
Berkowitz, Oren
Burke, Peter
Stern, Robert
Cantu, Robert

PMID: 27112592; PMCID: PMC5314982; DOI: 10.1089/neu.2016.4475;

Nguyen TN, Masoud H, Tarlov N, Holsapple J, Chin LS, Norbash AM. Expanding Endovascular Therapy of Very Small Ruptured Aneurysms with the 1.5-mm Coil. Interv Neurol. 2015 Oct; 4(1-2):59-63.View Related Profiles.

Masoud, Hesham
Holsapple, James
Nguyen, Thanh

PMID: 26600799; PMCID: PMC4640086; DOI: 10.1159/000437275;

Tschoe C, Holsapple JW, Binello E. Resection of Primary Brachial Plexus Tumor via a Modified Supraclavicular Approach. J Neurol Surg Rep. 2014 Aug; 75(1):e133-5.View Related Profiles.

Binello, Emanuela
Holsapple, James

PMID: 25083372; PMCID: PMC4110154; DOI: 10.1055/s-0034-1376423;

Qin B, Tabbara AK, Delalle I, Holsapple J, Hohler A. An enigmatic brainstem posterior fossa ganglioglioma in an adult. Int J Neurosci. 2014 Sep; 124(9):704-6.View Related Profiles.

Hohler, Anna
Delalle, Ivana
Holsapple, James

PMID: 24405263; DOI: 10.3109/00207454.2013.877901;

Burns JD, Green DM, Lau H, Winter M, Koyfman F, DeFusco CM, Holsapple JW, Kase CS. The effect of a neurocritical care service without a dedicated neuro-ICU on quality of care in intracerebral hemorrhage. Neurocrit Care. 2013 Jun; 18(3):305-12.View Related Profiles.

Kase, Carlos
Green, Deborah
Lau, Helena
Holsapple, James
Burns, Joseph

PMID: 23479068; DOI: 10.1007/s12028-013-9818-1;

Orehek EK, Burns JD, Koyfman F, Azocar RJ, Holsapple JW, Green DM. Postpartum trifecta: simultaneous eclamptic intracerebral hemorrhage, PRES, and herniation due to intracranial hypotension. Neurocrit Care. 2012 Dec; 17(3):434-8.View Related Profiles.

Green, Deborah
Holsapple, James
Burns, Joseph

PMID: 23011750; DOI: 10.1007/s12028-012-9742-9;

Doxtader EE, Butts SC, Holsapple JW, Fuller CE. Aggressive pediatric meningioma with soft tissue and lymph node metastases: a case report. Pediatr Dev Pathol. 2009 May-Jun; 12(3):244-8. PMID: 19086745; DOI: 10.2350/08-07-0501.1;

Gorji R, Wang J, Eller JL, Holsapple J. Deep hypothermic circulatory arrest for treatment of renal carcinoma. J Clin Anesth. 2009 May; 21(3):217-9. PMID: 19464618; DOI: 10.1016/j.jclinane.2008.06.041;

Caldicott CV, Holsapple JW. Training for fitness: reconsidering the 80-hour work week. Perspect Biol Med. 2008; 51(1):134-43. PMID: 18192772; DOI: 10.1353/pbm.2008.0000;

Motter BC, Holsapple J. Saccades and covert shifts of attention during active visual search: spatial distributions, memory, and items per fixation. Vision Res. 2007 May; 47(10):1261-81. PMID: 17418364

Darbar A, Krishnamurthy S, Holsapple JW, Hodge CJ. Ventral thoracic spinal cord herniation: frequently misdiagnosed entity. Spine (Phila Pa 1976). 2006 Aug 1; 31(17):E600-5. PMID: 16924199

Wasenko JJ, Lieberman KA, Rodziewicz GS, Holsapple JW. Magnetic resonance imaging characteristics of hyperacute hemorrhage in the brain and spine. Clin Imaging. 2002 Sep-Oct; 26(5):330-7. PMID: 12213367

Motter BC, Holsapple JW. Cortical image density determines the probability of target discovery during active search. Vision Res. 2000; 40(10-12):1311-22. PMID: 10788642

Wasenko JJ, Hochhauser L, Holsapple JW, Poe LB, Albanese SA, Cacayorin ED. MR of post traumatic spinal cord lesions. Unexpected improvement of hemorrhagic lesions. Clin Imaging. 1997 Jul-Aug; 21(4):246-51. PMID: 9215470

Wasenko JJ, Holsapple JW, Winfield JA. Cerebral venous thrombosis. Demonstration with magnetic resonance angiography. Clin Imaging. 1995 Jul-Sep; 19(3):153-61. PMID: 7553428

Vautrin J, Kriebel ME, Holsapple J. Further evidence for the dynamic formation of transmitter quanta at the neuromuscular junction. J Neurosci Res. 1992 Jun; 32(2):245-54. PMID: 1357188

Holsapple JW, Preston JB, Strick PL. The origin of thalamic inputs to the "hand" representation in the primary motor cortex. J Neurosci. 1991 Sep; 11(9):2644-54. PMID: 1715388

Kriebel ME, Vautrin J, Holsapple J. Transmitter release: prepackaging and random mechanism or dynamic and deterministic process. Brain Res Brain Res Rev. 1990 May-Aug; 15(2):167-78. PMID: 1980833

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 30 publications over 22 distinct years, with a maximum of 3 publications in 2019