Neuroimaging Research for Veterans (NeRVe) Center - Service Contract
08/01/2023 - 07/31/2028 (Multi-PI)
PI: Michael Alosco, PhD
VA Boston Healthcare System


Boston University Alzheimer's Disease Research Center
08/15/2021 - 06/30/2026 (Key Person)
PI: Ann C. McKee, MD
NIH/National Institute on Aging
5P30AG072978-03

Risk for Later-Life Cognitive Impairment, Neurobehavioral Dysregulation, and Dementia in Former Soccer and American Football Players: The Head Impact and Trauma Surveillance Study (HITSS)
02/01/2021 - 01/31/2026 (PI)
NIH/National Institute of Neurological Disorders & Stroke
5R01NS119651-03

Blood Biomarker Development and Validation in Chronic Traumatic Encephalopathy and Alzheimer's Disease and Alzheimer's Disease Related Dementias
06/01/2023 - 05/31/2025 (Multi-PI)
PI: Michael Alosco, PhD
NIH/National Institute of Neurological Disorders & Stroke
1RF1NS132290-01

Late Pathologies of Exposure to Repetitive Head Impacts from Contact Sports: White Matter and Vascular Contributions to Cognitive Impairment, Dementia, and Neuropsychiatric Symptoms
09/15/2021 - 08/31/2024 (Multi-PI)
PI: Michael Alosco, PhD
NIH/National Institute of Neurological Disorders & Stroke
1RF1NS122854-01

18F-PI-2620 Tau PET as a Biomarker for Chronic Traumatic Encephalopathy
03/15/2023 - 05/13/2024 (PI)
Life Molecular Imaging Ltd


In Vivo Detection of Chronic Traumatic Encephalopathy with 18F-MK-6240 Tau PET
01/01/2021 - 12/31/2023 (Multi-PI)
PI: Michael Alosco, PhD
The Regents of the University of California, San Francisco NIH NINDS
5R21NS120629-02

Alzheimer's Disease Neuroimaging Initiative 4 (ADNI 4)
09/15/2022 - 07/31/2023 (Subcontract PI)
University of Southern California NIH NIA
2U19AG024904-16

Human Tau Imaging
08/01/2020 - 07/31/2023 (Subcontract PI)
The Regents of the University of California, San Francisco Rainwater Char. Fdn


Repetitive Head Impact Exposure and Later-Life White Matter Signal Abnormalities: An Investigation in Former NFL Players, Subjects with Alzheimer's Disease, and Cognitively Normal Controls
08/01/2018 - 04/30/2023 (PI)
NIH/National Institute of Neurological Disorders & Stroke
5K23NS102399-05

Showing 10 of 12 results. Show All Results

1. Arciniega H, Baucom ZH, Tuz-Zahra F, Tripodis Y, John O, Carrington H, Kim N, Knyazhanskaya EE, Jung LB, Breedlove K, Wiegand TLT, Daneshvar DH, Rushmore RJ, Billah T, Pasternak O, Coleman MJ, Adler CH, Bernick C, Balcer LJ, Alosco ML, Koerte IK, Lin AP, Cummings JL, Reiman EM, Stern RA, Shenton ME, Bouix S. Brain morphometry in former American football players: Findings from the DIAGNOSE CTE research project. Brain. 2024 Mar 27.View Related Profiles.

   Daneshvar, Daniel
   Alosco, Michael
   Rushmore, Richard
   Stern, Robert
   Tripodis, Yorghos
   

   PMID: 38533783
2. Alosco ML, Tartaglia MC. Repetitive Blast Injury and CSF Alzheimer Disease Biomarkers: Navigating a Complex Narrative. Neurology. 2024 Apr 09; 102(7):e209294. PMID: 38478855
3. Culhane JE, Jackson C, Tripodis Y, Nowinski C, Dams-O'Connor K, Pettway E, Uretsky M, Abdolmohammadi B, Nair E, Martin B, Palmisano J, Katz DI, Dwyer B, Daneshvar DH, Goldstein LE, Kowall NW, Cantu RC, Stern RA, Huber B, Crary J, Mez J, Stein TD, McKee AC, Alosco ML. Lack of association of informant-reported traumatic brain injury and chronic traumatic encephalopathy. J Neurotrauma. 2024 Mar 06.View Related Profiles.

   McKee, Ann
   Huber, Bertrand
   Dwyer, Brigid
   Nowinski, Christopher
   Daneshvar, Daniel
   Katz, Douglas
   Mez, Jesse
   Goldstein, Lee
   Alosco, Michael
   Kowall, Neil
   Stern, Robert
   Stein, Thor
   Tripodis, Yorghos
   

   PMID: 38445389
4. Banks SJ, Yhang E, Tripodis Y, Su Y, Protas H, Adler CH, Balcer LJ, Bernick C, Mez JB, Palmisano J, Barr WB, Wethe JV, Dodick DW, Mcclean MD, Martin B, Hartlage K, Turner A, Turner RW, Malhotra A, Colman M, Pasternak O, Lin AP, Koerte IK, Bouix S, Cummings JL, Shenton ME, Reiman EM, Stern RA, Alosco ML. Clinical Outcomes and Tau Pathology in Retired Football Players: Associations With Diagnosed and Witnessed Sleep Apnea. Neurol Clin Pract. 2024 Apr; 14(2):e200263.View Related Profiles.

   Mez, Jesse
   Alosco, Michael
   McClean, Michael
   Stern, Robert
   Tripodis, Yorghos
   

   PMID: 38425491; PMCID: PMC10900387; DOI: 10.1212/CPJ.0000000000200263;
5. Alexander A, Alvarez VE, Huber BR, Alosco ML, Mez J, Tripodis Y, Nicks R, Katz DI, Dwyer B, Daneshvar DH, Martin B, Palmisano J, Goldstein LE, Crary JF, Nowinski C, Cantu RC, Kowall NW, Stern RA, Delalle I, McKee AC, Stein TD. Cortical-sparing chronic traumatic encephalopathy (CSCTE): a distinct subtype of CTE. Acta Neuropathol. 2024 Feb 26; 147(1):45.View Related Profiles.

   McKee, Ann
   Huber, Bertrand
   Dwyer, Brigid
   Nowinski, Christopher
   Daneshvar, Daniel
   Katz, Douglas
   Delalle, Ivana
   Mez, Jesse
   Goldstein, Lee
   Alosco, Michael
   Kowall, Neil
   Stern, Robert
   Stein, Thor
   Alvarez, Victor
   Tripodis, Yorghos
   

   PMID: 38407651
6. van Amerongen S, Pulukuri SV, Tuz-Zahra F, Tripodis Y, Cherry JD, Bernick C, Geda YE, Wethe JV, Katz DI, Alosco ML, Adler CH, Balcer LJ, Ashton NJ, Blennow K, Zetterberg H, Daneshvar DH, Colasurdo EA, Iliff JJ, Li G, Peskind ER, Shenton ME, Reiman EM, Cummings JL, Stern RA. Inflammatory biomarkers for neurobehavioral dysregulation in former American football players: findings from the DIAGNOSE CTE Research Project. J Neuroinflammation. 2024 Feb 09; 21(1):46.View Related Profiles.

   Daneshvar, Daniel
   Katz, Douglas
   Cherry, Jonathan
   Alosco, Michael
   Stern, Robert
   Van Amerongen, Suzan
   Tripodis, Yorghos
   

   PMID: 38336728; PMCID: PMC10854026; DOI: 10.1186/s12974-024-03034-6;
7. Alosco ML, White M, Bell C, Faheem F, Tripodis Y, Yhang E, Baucom Z, Martin B, Palmisano J, Dams-O'Connor K, Crary JF, Goldstein LE, Katz DI, Dwyer B, Daneshvar DH, Nowinski C, Cantu RC, Kowall NW, Stern RA, Alvarez VE, Huber BR, Stein TD, McKee AC, Mez J. Cognitive, functional, and neuropsychiatric correlates of regional tau pathology in autopsy-confirmed chronic traumatic encephalopathy. Mol Neurodegener. 2024 Feb 06; 19(1):10.View Related Profiles.

   McKee, Ann
   Huber, Bertrand
   Dwyer, Brigid
   Nowinski, Christopher
   Daneshvar, Daniel
   Katz, Douglas
   Mez, Jesse
   Goldstein, Lee
   Alosco, Michael
   Kowall, Neil
   Stern, Robert
   Stein, Thor
   Alvarez, Victor
   Tripodis, Yorghos
   

   PMID: 38317248; PMCID: PMC10845638; DOI: 10.1186/s13024-023-00697-2;
8. Montoliu-Gaya L, Alosco ML, Yhang E, Tripodis Y, Sconzo D, Ally M, Grötschel L, Ashton NJ, Lantero-Rodriguez J, Sauer M, Gomes B, Nilsson J, Brinkmalm G, Sugarman MA, Aparicio HJ, Martin B, Palmisano JN, Steinberg EG, Simkin I, Turk KW, Budson AE, Au R, Farrer L, Jun GR, Kowall NW, Stern RA, Goldstein LE, Qiu WQ, Mez J, Huber BR, Alvarez VE, McKee AC, Zetterberg H, Gobom J, Stein TD, Blennow K. Optimal blood tau species for the detection of Alzheimer's disease neuropathology: an immunoprecipitation mass spectrometry and autopsy study. Acta Neuropathol. 2023 Dec 30; 147(1):5.View Related Profiles.

   Budson, Andrew
   McKee, Ann
   Huber, Bertrand
   Sconzo, Daniel
   Steinberg, Eric
   Jun, Gyungah
   Aparicio, Hugo
   Mez, Jesse
   Turk, Katherine
   Goldstein, Lee
   Farrer, Lindsay
   Alosco, Michael
   Kowall, Neil
   Au, Rhoda
   Stern, Robert
   Stein, Thor
   Alvarez, Victor
   Tripodis, Yorghos
   

   PMID: 38159140; PMCID: PMC10757700; DOI: 10.1007/s00401-023-02660-3;
9. Su Y, Protas H, Luo J, Chen K, Alosco ML, Adler CH, Balcer LJ, Bernick C, Au R, Banks SJ, Barr WB, Coleman MJ, Dodick DW, Katz DI, Marek KL, McClean MD, McKee AC, Mez J, Daneshvar DH, Palmisano JN, Peskind ER, Turner RW, Wethe JV, Rabinovici G, Johnson K, Tripodis Y, Cummings JL, Shenton ME, Stern RA, Reiman EM. Flortaucipir tau PET findings from former professional and college American football players in the DIAGNOSE CTE research project. Alzheimers Dement. 2024 Mar; 20(3):1827-1838.View Related Profiles.

   McKee, Ann
   Daneshvar, Daniel
   Katz, Douglas
   Mez, Jesse
   Alosco, Michael
   McClean, Michael
   Au, Rhoda
   Stern, Robert
   Tripodis, Yorghos
   

   PMID: 38134231
10. Ly MT, Tuz-Zahra F, Tripodis Y, Adler CH, Balcer LJ, Bernick C, Zetterberg H, Blennow K, Peskind ER, Au R, Banks SJ, Barr WB, Wethe JV, Bondi MW, Delano-Wood LM, Cantu RC, Coleman MJ, Dodick DW, McClean MD, Mez JB, Palmisano J, Martin B, Hartlage K, Lin AP, Koerte IK, Cummings JL, Reiman EM, Shenton ME, Stern RA, Bouix S, Alosco ML. Association of Vascular Risk Factors and CSF and Imaging Biomarkers With White Matter Hyperintensities in Former American Football Players. Neurology. 2024 Jan 23; 102(2):e208030.View Related Profiles.

    Mez, Jesse
    Alosco, Michael
    McClean, Michael
    Ly, Monica
    Au, Rhoda
    Stern, Robert
    Tripodis, Yorghos
    

    PMID: 38165330; PMCID: PMC10870736; DOI: 10.1212/WNL.0000000000208030;

Showing 10 of 206 results. Show More

BU researchers publish ‘crucial’ study that could help diagnose CTE before death

Researchers get closer to diagnosing CTE in living patients

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New Findings in Football Players May Aid the Future Diagnosis and Study of Chronic Traumatic Encephalopathy (CTE)

What MRI-Derived Data and Other Factors Reveal About White Matter Hyperintensity in Former Football Players

Former Pro Football Players Show Troubling Brain Changes

Study of former football players shows brain changes

Former Pro Football Players Show Troubling Brain Changes

AAN study reveals Brain Lesions in Former Football Players Linked to Vascular, Brain Changes

Study of former football players shows brain changes

Football linked to more brain damage beyond white matter marks

Changes in the Diagnostic Process of Alzheimer Disease: A New Era of Blood-Based Approaches

Can Playing Football Increase Parkinson’s Risk?

Heads up: Concussions are common in soccer — especially for girls — but rules are changing to keep young athletes safe

Playing football can increase risk of Parkinson’s. Would you let your child play?

Playing Football Linked to Higher Parkinson's Risk

Can playing football increase Parkinson’s risk?

Playing Football Linked to Higher Parkinson's Risk

Playing football may increase risk of Parkinson’s disease, study suggests

Playing tackle football may raise the risk for Parkinson’s disease: Boston University CTE Center

Playing football may increase risk for Parkinson's disease, study says

Playing Football Might Raise Parkinson's Risk

Playing Football Linked to Increased Parkinson's Ris

Football players at increased risk for Parkinson's disease, study finds

Playing football may increase risk of Parkinson’s disease, study suggests

Playing Football Might Raise Parkinson's Risk

Playing Football May Increase the Risk for Developing Parkinson’s Disease

Playing tackle football at an early age increases risk for brain decline later

Long football careers linked to impulsive behavior, less white matter in the brain: Boston University CTE study

New BU Study Finds Tackle Football at Young Age Raises Risk for Brain Decline Later

Former Bronco plans to donate brain for concussion research: "If they want my brain they can have it"

Alzheimer's: Could beer hop compounds help reduce toxic clumps?

CTE: The Mysterious Brain Disorder That’s Taken Over the NFL

Boston University Researchers Study Contact Sports' Impact On Brains

Kraken broadcaster JT Brown said he plans to donate his brain to CTE research

White Matter Hyperintensities Linked to Repetitive Head Trauma

Could Structural MRI Findings Help Detect CTE During Life?

MRI Might Spot Concussion-Linked CTE in Living Patients

MRI Might Spot Concussion-Linked CTE in Living Patient

MRI Key to Diagnosing CTE in Living Patients?

More Years Playing Football, More Brain Lesions on MRI: Study

More Years Playing Football, More Brain Lesions on MRI: Study

Men who were in boxing clubs as youngsters may be THREE times as likely to develop Alzheimer's disease, study warns

Post-TBI Cognitive Changes 'Strikingly' Similar to Early Parkinson's

Researchers receive $460,000 NIH grant for brain imaging study

Repeated Head Impact Linked With Emotional, Cognitive Problems Later in Life

Repetitive Hits to the Head Tied To Depression, Poor Cognition in Later Life

Repeat Head Impacts May Lead to Depression Later

Repeated head impacts, brain injury increase risk for depression

Hype or horror? The risk of CTE brain disease divides football and medical communities

Ex-NFL Players Six Times More Likely than the General Public to Report Cognitive Problems, Study Finds

Rochester Woman Advocates for Alzheimer's Caregivers

Deeper Dive Into CTE, Dementia in Football Reveals New Players

What Years of Playing Football Does to Brain’s White Matter

Triple Threat: Tau, Atrophy, and Arteriolosclerosis Push CTE Toward Dementia

Five New Answers About the Link Between Football, CTE, and Dementia

Football Head Trauma Linked Again to Long-Term Brain Damage

Dementia Tied to White Matter Rarefaction in Football Players With CTE

Football Head Trauma Linked Again to Long-Term Brain Damage

On the Precipice of Memory Loss: Pursuing Better Diagnostic Tools for Patients with CTE and Other Neurodegenerative Disorders

Dementia-related marker found in former pro athletes with concussion history

For Patients With Memory Loss, Working Towards Better Diagnosis

Free Event for Caregivers

How A Massachusetts Bill Could Affect Local Pop Warner Teams

California bill would limit tackling during youth practices. Why it has leagues’ support

Subconcussive Head Impacts Alter Oculomotor Responses

Can Playing Football Lead Your Child To Develop a Disability?

Starting tackle football early sets kids up for brain problems

MED Researchers: Youth Football Linked to Earlier Brain Problems

Playing tackle footall before 12 can lead to long-term consequences