Risk and Resilience, Clinical presentation, and Biomarker Profiles of Chronic Traumatic Encephalopathy and Related Dementias: The DIAGNOSE CTE Research Project II
08/15/2024 - 07/31/2029 (Multi-PI)
PI: Michael Alosco, PhD
NIH/National Institute of Neurological Disorders & Stroke
1R01NS139383-01

Neuroimaging Research for Veterans (NeRVe) Center - Service Contract
08/01/2023 - 07/31/2028 (Multi-PI)
PI: Michael Alosco, PhD
VA Boston Healthcare System


Validation of Lens Beta-Amyloid as a Novel Biomarker for Early Detection of Alzheimer's Disease at the Boston University Alzheimer's Disease Research
09/30/2023 - 06/30/2028 (Multi-PI)
PI: Michael Alosco, PhD
NIH/National Institute on Aging
5R01AG077588-02

Late Pathologies of Exposure to Repetitive Head Impacts from Contact Sports: White Matter and Vascular Contributions to Cognitive Impairment, Dementia, and Neuropsychiatric Symptoms
09/01/2024 - 08/31/2026 (PI)
NIH/National Institute of Neurological Disorders & Stroke
4R01NS122854-02

Boston University Alzheimer's Disease Research Center
08/15/2021 - 06/30/2026 (Key Person)
PI: Ann C. McKee, MD
NIH/National Institute on Aging
5P30AG072978-04

Risk for Later-Life Cognitive Impairment, Neurobehavioral Dysregulation, and Dementia in Former Soccer and American Football Players: The Head Impact and Trauma Surveillance Study (HITSS)
02/01/2021 - 01/31/2026 (PI)
NIH/National Institute of Neurological Disorders & Stroke
5R01NS119651-04

18F-PI-2620 Tau PET as a Biomarker for Chronic Traumatic Encephalopathy
03/15/2023 - 12/04/2025 (PI)
Life Molecular Imaging Ltd


Alzheimer's Disease Neuroimaging Initiative (ADNI4)
08/01/2024 - 07/31/2025 (Subcontract PI)
Fordham University NIH NIA
5U19AG024904-17

Alzheimer's Disease Neuroimaging Initiative 4 (ADNI 4)
09/15/2022 - 07/31/2025 (Subcontract PI)
University of Southern California NIH NIA
5U19AG024904-17

Blood Biomarker Development and Validation in Chronic Traumatic Encephalopathy and Alzheimer's Disease and Alzheimer's Disease Related Dementias
06/01/2023 - 05/31/2025 (Multi-PI)
PI: Michael Alosco, PhD
NIH/National Institute of Neurological Disorders & Stroke
1RF1NS132290-01

Showing 10 of 18 results. Show All Results

1. Cantu RC, Sills AK, Alosco ML, Arbogast KB, Bazarian JJ, Bieniek KF, Crandall JR, Iverson GL, Katz DI, Keene CD, Leddy JJ, Mack CD, McKee AC, Meehan WP, Mez J, Nowinski CJ, Okonkwo DO, Solomon GS, Stein TD, Tartaglia MC, Zafonte RD, Daneshvar DH. Prevention of concussion and long-term effects of repetitive traumatic brain injury: Unanimous consensus from the Cantu Concussion Summit. PM R. 2025 Mar 05. PMID: 40040623; DOI: 10.1002/pmrj.13332;
2. Alosco ML, Mejía Pérez J, Culhane JE, Shankar R, Nowinski CJ, Bureau S, Mundada N, Smith K, Amuiri A, Asken B, Groh JR, Miner A, Pettway E, Mosaheb S, Tripodis Y, Windon C, Mercier G, Stern RA, Grinberg LT, Soleimani-Meigooni DN, Christian BT, Betthauser TJ, Stein TD, McKee AC, Mathis CA, Abrahamson EE, Ikonomovic MD, Johnson SC, Mez J, La Joie R, Schonhaut D, Rabinovici GD. 18F-MK-6240 tau PET in patients at-risk for chronic traumatic encephalopathy. Mol Neurodegener. 2025 Feb 25; 20(1):23.View Related Profiles.

   McKee, Ann
   Miner, Annalise
   Nowinski, Christopher
   Groh, Jenna
   Mez, Jesse
   Alosco, Michael
   Stern, Robert
   Stein, Thor
   Tripodis, Yorghos
   

   PMID: 39994806; PMCID: PMC11852567; DOI: 10.1186/s13024-025-00808-1;
3. Altaras C, Ly MT, Schultz O, Barr WB, Banks SJ, Wethe JV, Tripodis Y, Adler CH, Balcer LJ, Bernick C, Zetterberg H, Blennow K, Ashton N, Peskind E, Cantu RC, Coleman MJ, Lin AP, Koerte IK, Bouix S, Daneshvar D, Dodick DW, Geda YE, Katz DL, Weller JL, Mez J, Palmisano JN, Martin B, Cummings JL, Reiman EM, Shenton ME, Stern RA, Alosco ML. Dispersion-based cognitive intra-individual variability in former American football players: Association with traumatic encephalopathy syndrome, repetitive head impacts, and biomarkers. Clin Neuropsychol. 2025 Jan 26; 1-29.View Related Profiles.

   Altaras, Caroline
   Daneshvar, Daniel
   Mez, Jesse
   Palmisano, Joseph
   Alosco, Michael
   Ly, Monica
   Stern, Robert
   Tripodis, Yorghos
   

   PMID: 39865747
4. Ly MT, Altaras C, Tripodis Y, Adler CH, Balcer LJ, Bernick C, Zetterberg H, Blennow K, Peskind ER, Banks SJ, Barr WB, Wethe JV, Lenio S, Bondi MW, Delano-Wood LM, Cantu RC, Coleman MJ, Dodick DW, Mez J, Daneshvar DH, Palmisano JN, Martin B, Lin AP, Koerte IK, Bouix S, Cummings JL, Reiman EM, Shenton ME, Stern RA, Alosco ML. Single- versus two-test criteria for cognitive impairment: associations with CSF and imaging markers in former American football players. Clin Neuropsychol. 2025 Jan 20; 1-25.View Related Profiles.

   Altaras, Caroline
   Daneshvar, Daniel
   Mez, Jesse
   Palmisano, Joseph
   Alosco, Michael
   Ly, Monica
   Stern, Robert
   Lenio, Steven
   Tripodis, Yorghos
   

   PMID: 39834028
5. Asken BM, Brett BL, Barr WB, Banks S, Wethe JV, Dams-O'Connor K, Stern RA, Alosco ML. Chronic traumatic encephalopathy: State-of-the-science update and narrative review. Clin Neuropsychol. 2025 Jan 20; 1-25.View Related Profiles.

   Alosco, Michael
   Stern, Robert
   

   PMID: 39834035
6. Richardson TE, Orr ME, Orr TC, Rohde SK, Ehrenberg AJ, Thorn EL, Christie TD, Flores-Almazan V, Afzal R, De Sanctis C, Maldonado-Díaz C, Hiya S, Canbeldek L, Kulumani Mahadevan LS, Slocum C, Samanamud J, Clare K, Scibetta N, Yokoda RT, Koenigsberg D, Marx GA, Kauffman J, Goldstein A, Selmanovic E, Drummond E, Wisniewski T, White CL, Goate AM, Crary JF, Farrell K, Alosco ML, Mez J, McKee AC, Stein TD, Bieniek KF, Kautz TF, Daoud EV, Walker JM. Spatial proteomic differences in chronic traumatic encephalopathy, Alzheimer's disease, and primary age-related tauopathy hippocampi. Alzheimers Dement. 2025 Feb; 21(2):e14487.View Related Profiles.

   McKee, Ann
   Mez, Jesse
   Alosco, Michael
   Stein, Thor
   

   PMID: 39737785; PMCID: PMC11848160; DOI: 10.1002/alz.14487;
7. Nicks R, Shah A, Stathas SA, Kirsch D, Horowitz SM, Saltiel N, Calderazzo SM, Butler MLMD, Cormier KA, Aytan N, Tu-Zahra F, Mathias R, Faheem F, Marcus S, Spurlock E, Fishbein L, Esnault CD, Boden A, Rosen G, Xia W, Daley S, Meng G, Martin BR, Daneshvar DH, Nowinski CJ, Alosco ML, Mez J, Tripodis Y, Huber BR, Alvarez VE, Cherry JD, McKee AC, Stein TD. Neurodegeneration in the cortical sulcus is a feature of chronic traumatic encephalopathy and associated with repetitive head impacts. Acta Neuropathol. 2024 Dec 06; 148(1):79.View Related Profiles.

   McKee, Ann
   Nowinski, Christopher
   Daneshvar, Daniel
   Mez, Jesse
   Cherry, Jonathan
   Alosco, Michael
   Aytan, Nurgul
   Calderazzo, Samantha
   Stein, Thor
   Alvarez, Victor
   Tripodis, Yorghos
   

   PMID: 39643767; PMCID: PMC11624223; DOI: 10.1007/s00401-024-02833-8;
8. Abdolmohammadi B, Tuz-Zahra F, Uretsky M, Nicks R, Mosaheb S, Labonte J, Yhang E, Durape S, Martin B, Palmisano J, Nowinski C, Cherry JD, Alvarez VE, Huber BR, Dams-O'Connor K, Crary J, Dwyer B, Daneshvar DH, Goldstein LE, Au R, Katz DI, Kowall NW, Cantu RC, Stern RA, Alosco ML, Stein TD, Tripodis Y, McKee AC, Mez J. Duration of Ice Hockey Play and Chronic Traumatic Encephalopathy. JAMA Netw Open. 2024 Dec 02; 7(12):e2449106.View Related Profiles.

   McKee, Ann
   Dwyer, Brigid
   Nowinski, Christopher
   Daneshvar, Daniel
   Katz, Douglas
   Mez, Jesse
   Cherry, Jonathan
   Palmisano, Joseph
   Goldstein, Lee
   Alosco, Michael
   Kowall, Neil
   Au, Rhoda
   Stern, Robert
   Stein, Thor
   Alvarez, Victor
   Tripodis, Yorghos
   

   PMID: 39630446; PMCID: PMC11618473; DOI: 10.1001/jamanetworkopen.2024.49106;
9. Uretsky M, Nair E, Burton R, Cronin SW, Rousseau D, Tuz-Zahra F, Durape S, Abdolmohammadi B, Baucom Z, Saltiel N, Shah A, Martin B, Palmisano J, Cherry JD, Daneshvar D, Dwyer B, Dams-O'Connor K, Crary J, Goldstein L, Huber B, Katz D, Kowall N, Cantu RC, Alvarez VE, Stern RA, Stein TD, Tripodis Y, McKee AC, Alosco ML, Mez J. Chronic Traumatic Encephalopathy, Family History of Mental Illness, and Aggression in Brain Donors With Repetitive Head Impact Exposure. Neurology. 2024 Dec 24; 103(12):e210056.View Related Profiles.

   McKee, Ann
   Dwyer, Brigid
   Daneshvar, Daniel
   Katz, Douglas
   Mez, Jesse
   Cherry, Jonathan
   Palmisano, Joseph
   Goldstein, Lee
   Alosco, Michael
   Kowall, Neil
   Stern, Robert
   Stein, Thor
   Alvarez, Victor
   Tripodis, Yorghos
   

   PMID: 39602665; PMCID: PMC11604107; DOI: 10.1212/WNL.0000000000210056;
10. Prasad M, Goodman D, Gutta S, Sheikh Z, Cabral HJ, Shunyakova J, Sanjiv N, Curley C, Yarala RR, Tsai L, Siegel NH, Chen X, Poulaki V, Alosco ML, Stein TD, Ness S, Subramanian ML. Associations Between Retinal Vascular Occlusions and Dementia. Healthcare (Basel). 2024 Nov 26; 12(23).View Related Profiles.

    Cabral, Howard
    Subramanian, Manju
    Alosco, Michael
    Prasad, Minali
    Siegel, Nicole
    Yarala, Rohun
    Stein, Thor
    

    PMID: 39684995; PMCID: PMC11641452; DOI: 10.3390/healthcare12232371;

Showing 10 of 234 results. Show More

Dolphins quarterback set to return to practice after 3rd NFL concussion

“It Will Make CTE a Treatable Disease”: The Race for a Diagnosis in Life

Research on CTE and Concussions Changed the NFL. Experts Say That’s Not Enough

10 Things BU CTE Center Research Has Taught Us About the Brain Dangers of Contact Sports and Military Service

What Is CTE?

'Physician Spending Is Not the Problem in Healthcare': What We Heard This Week (

One in Three Former NFL Players Believe They Have CTE

As denials pile up, NFL settlement ignores ‘critical’ tests

BU researchers publish ‘crucial’ study that could help diagnose CTE before death

Researchers get closer to diagnosing CTE in living patients

New Findings in Football Players May Aid the Future Diagnosis and Study of Chronic Traumatic Encephalopathy (CTE)

What MRI-Derived Data and Other Factors Reveal About White Matter Hyperintensity in Former Football Players

Former Pro Football Players Show Troubling Brain Changes

Study of former football players shows brain changes

Former Pro Football Players Show Troubling Brain Changes

AAN study reveals Brain Lesions in Former Football Players Linked to Vascular, Brain Changes

Study of former football players shows brain changes

Football linked to more brain damage beyond white matter marks

Changes in the Diagnostic Process of Alzheimer Disease: A New Era of Blood-Based Approaches

Can Playing Football Increase Parkinson’s Risk?

Heads up: Concussions are common in soccer — especially for girls — but rules are changing to keep young athletes safe

Playing football can increase risk of Parkinson’s. Would you let your child play?

Playing Football Linked to Higher Parkinson's Risk

Can playing football increase Parkinson’s risk?

Playing Football Linked to Higher Parkinson's Risk

Playing football may increase risk of Parkinson’s disease, study suggests

Playing tackle football may raise the risk for Parkinson’s disease: Boston University CTE Center

Playing football may increase risk for Parkinson's disease, study says

Playing Football Might Raise Parkinson's Risk

Playing Football Linked to Increased Parkinson's Ris

Football players at increased risk for Parkinson's disease, study finds

Playing football may increase risk of Parkinson’s disease, study suggests

Playing Football Might Raise Parkinson's Risk

Playing Football May Increase the Risk for Developing Parkinson’s Disease

Playing tackle football at an early age increases risk for brain decline later

Long football careers linked to impulsive behavior, less white matter in the brain: Boston University CTE study

New BU Study Finds Tackle Football at Young Age Raises Risk for Brain Decline Later

Former Bronco plans to donate brain for concussion research: "If they want my brain they can have it"

Alzheimer's: Could beer hop compounds help reduce toxic clumps?

CTE: The Mysterious Brain Disorder That’s Taken Over the NFL

Boston University Researchers Study Contact Sports' Impact On Brains

Kraken broadcaster JT Brown said he plans to donate his brain to CTE research

White Matter Hyperintensities Linked to Repetitive Head Trauma

Could Structural MRI Findings Help Detect CTE During Life?

MRI Might Spot Concussion-Linked CTE in Living Patients

MRI Might Spot Concussion-Linked CTE in Living Patient

MRI Key to Diagnosing CTE in Living Patients?

More Years Playing Football, More Brain Lesions on MRI: Study

More Years Playing Football, More Brain Lesions on MRI: Study

Men who were in boxing clubs as youngsters may be THREE times as likely to develop Alzheimer's disease, study warns

Post-TBI Cognitive Changes 'Strikingly' Similar to Early Parkinson's

Researchers receive $460,000 NIH grant for brain imaging study

Repeated Head Impact Linked With Emotional, Cognitive Problems Later in Life

Repetitive Hits to the Head Tied To Depression, Poor Cognition in Later Life

Repeat Head Impacts May Lead to Depression Later

Repeated head impacts, brain injury increase risk for depression

Hype or horror? The risk of CTE brain disease divides football and medical communities

Ex-NFL Players Six Times More Likely than the General Public to Report Cognitive Problems, Study Finds

Rochester Woman Advocates for Alzheimer's Caregivers

Deeper Dive Into CTE, Dementia in Football Reveals New Players

What Years of Playing Football Does to Brain’s White Matter

Triple Threat: Tau, Atrophy, and Arteriolosclerosis Push CTE Toward Dementia

Five New Answers About the Link Between Football, CTE, and Dementia

Football Head Trauma Linked Again to Long-Term Brain Damage

Dementia Tied to White Matter Rarefaction in Football Players With CTE

Football Head Trauma Linked Again to Long-Term Brain Damage

On the Precipice of Memory Loss: Pursuing Better Diagnostic Tools for Patients with CTE and Other Neurodegenerative Disorders

Dementia-related marker found in former pro athletes with concussion history

For Patients With Memory Loss, Working Towards Better Diagnosis

Free Event for Caregivers

How A Massachusetts Bill Could Affect Local Pop Warner Teams

California bill would limit tackling during youth practices. Why it has leagues’ support

Subconcussive Head Impacts Alter Oculomotor Responses

Can Playing Football Lead Your Child To Develop a Disability?

Starting tackle football early sets kids up for brain problems

MED Researchers: Youth Football Linked to Earlier Brain Problems

Playing tackle footall before 12 can lead to long-term consequences