The Contribution of Repetitive Head Impacts and Social Determinants of Health to Brain Aging in Older Adult Black Men
08/15/2023 - 07/31/2028 (Subcontract PI)
The George Washington University NIH NINDS
5R01NS134043-02

Neuroimaging Research for Veterans (NeRVe) Center - Service Contract
08/01/2023 - 07/31/2028 (Multi-PI)
PI: Michael Alosco, PhD
VA Boston Healthcare System


Validation of Lens Beta-Amyloid as a Novel Biomarker for Early Detection of Alzheimer's Disease at the Boston University Alzheimer's Disease Research
09/30/2023 - 06/30/2028 (Multi-PI)
PI: Michael Alosco, PhD
NIH/National Institute on Aging
5R01AG077588-02

Boston University Alzheimer's Disease Research Center
08/15/2021 - 06/30/2026 (Key Person)
PI: Ann C. McKee, MD
NIH/National Institute on Aging
5P30AG072978-03

Risk for Later-Life Cognitive Impairment, Neurobehavioral Dysregulation, and Dementia in Former Soccer and American Football Players: The Head Impact and Trauma Surveillance Study (HITSS)
02/01/2021 - 01/31/2026 (PI)
NIH/National Institute of Neurological Disorders & Stroke
5R01NS119651-04

Blood Biomarker Development and Validation in Chronic Traumatic Encephalopathy and Alzheimer's Disease and Alzheimer's Disease Related Dementias
06/01/2023 - 05/31/2025 (Multi-PI)
PI: Michael Alosco, PhD
NIH/National Institute of Neurological Disorders & Stroke
1RF1NS132290-01

18F-PI-2620 Tau PET as a Biomarker for Chronic Traumatic Encephalopathy
03/15/2023 - 12/31/2024 (PI)
Life Molecular Imaging Ltd


The 1988 NFL Survey Study
12/15/2023 - 12/14/2024 (PI)
ESPN Productions, Inc.


Late Pathologies of Exposure to Repetitive Head Impacts from Contact Sports: White Matter and Vascular Contributions to Cognitive Impairment, Dementia, and Neuropsychiatric Symptoms
09/15/2021 - 08/31/2024 (Multi-PI)
PI: Michael Alosco, PhD
NIH/National Institute of Neurological Disorders & Stroke
1RF1NS122854-01

Alzheimer's Disease Neuroimaging Initiative 4 (ADNI 4)
09/15/2022 - 07/31/2024 (Subcontract PI)
University of Southern California NIH NIA
5U19AG024904-17

Showing 10 of 15 results. Show All Results

1. Adams JW, Kirsch D, Calderazzo SM, Tuz-Zahra F, Tripodis Y, Mez J, Alosco ML, Alvarez VE, Huber BR, Kubilus C, Cormier KA, Nicks R, Uretsky M, Nair E, Kuzyk E, Aytan N, Cherry JD, Crary JF, Daneshvar DH, Nowinski CJ, Goldstein LE, Dwyer B, Katz DI, Cantu RC, Stern RA, McKee AC, Stein TD. Substantia Nigra Pathology, Contact Sports Play, and Parkinsonism in Chronic Traumatic Encephalopathy. JAMA Neurol. 2024 Sep 01; 81(9):916-924.View Related Profiles.

   McKee, Ann
   Huber, Bertrand
   Dwyer, Brigid
   Nowinski, Christopher
   Daneshvar, Daniel
   Katz, Douglas
   Mez, Jesse
   Cherry, Jonathan
   Goldstein, Lee
   Alosco, Michael
   Aytan, Nurgul
   Stern, Robert
   Stein, Thor
   Alvarez, Victor
   Tripodis, Yorghos
   

   PMID: 39008284; PMCID: PMC11250391; DOI: 10.1001/jamaneurol.2024.2166;
2. Asken BM, Bove JM, Bauer RM, Tanner JA, Casaletto KB, Staffaroni AM, VandeVrede L, Alosco ML, Mez JB, Stern RA, Miller BL, Grinberg LT, Boxer AL, Gorno-Tempini ML, Rosen HJ, Rabinovici GD, Kramer JH. Clinical implications of head trauma in frontotemporal dementia and primary progressive aphasia. Alzheimers Res Ther. 2024 Aug 29; 16(1):193.View Related Profiles.

   Mez, Jesse
   Alosco, Michael
   Stern, Robert
   

   PMID: 39210451; PMCID: PMC11363650; DOI: 10.1186/s13195-024-01553-1;
3. Jung LB, Wiegand TLT, Tuz-Zahra F, Tripodis Y, Iliff JJ, Piantino J, Arciniega H, Kim CL, Pankatz L, Bouix S, Lin AP, Alosco ML, Daneshvar DH, Mez J, Sepehrband F, Rathi Y, Pasternak O, Coleman MJ, Adler CH, Bernick C, Balcer L, Cummings JL, Reiman EM, Stern RA, Shenton ME, Koerte IK. Repetitive Head Impacts and Perivascular Space Volume in Former American Football Players. JAMA Netw Open. 2024 Aug 01; 7(8):e2428687.View Related Profiles.

   Daneshvar, Daniel
   Mez, Jesse
   Alosco, Michael
   Stern, Robert
   Tripodis, Yorghos
   

   PMID: 39186275
4. Akhter-Khan SC, Tao Q, Ang TFA, Karjadi C, Itchapurapu IS, Libon DJ, Alosco M, Mez J, Qiu WQ, Au R. Cerebral Microbleeds in Different Brain Regions and Their Associations With the Digital Clock-Drawing Test: Secondary Analysis of the Framingham Heart Study. J Med Internet Res. 2024 Jul 29; 26:e45780.View Related Profiles.

   Itchapurapu, Indira Swetha
   Mez, Jesse
   Alosco, Michael
   Tao, Qiushan
   Au, Rhoda
   Ang, Ting Fang Alvin
   

   PMID: 39073857; PMCID: PMC11319892; DOI: 10.2196/45780;
5. Pulukuri SV, Fagle TR, Trujillo-Rodriguez D, van Amerongen S, Bernick C, Geda YE, Wethe JV, Peskind ER, Katz DI, Alosco ML, Palmisano JN, Tripodis Y, Adler CH, Balcer LJ, Reiman EM, Shenton ME, Cummings JL, Stern RA. Characterizing Neurobehavioral Dysregulation Among Former American Football Players: Findings From the DIAGNOSE CTE Research Project. J Neuropsychiatry Clin Neurosci. 2024 Jul 22; appineuropsych20230133.View Related Profiles.

   Katz, Douglas
   Alosco, Michael
   Stern, Robert
   Van Amerongen, Suzan
   Tripodis, Yorghos
   

   PMID: 39034669
6. Culhane JE, Jackson CE, Tripodis Y, Nowinski CJ, Dams-O'Connor K, Pettway E, Uretsky M, Abdolmohammadi B, Nair E, Martin B, Palmisano J, Katz DI, Dwyer B, Daneshvar DH, Goldstein LE, Kowall NW, Cantu RC, Stern RA, Huber BR, Crary JF, Mez J, Stein TD, McKee AC, Alosco ML. Lack of Association of Informant-Reported Traumatic Brain Injury and Chronic Traumatic Encephalopathy. J Neurotrauma. 2024 Jun; 41(11-12):1399-1408.View Related Profiles.

   McKee, Ann
   Huber, Bertrand
   Dwyer, Brigid
   Nowinski, Christopher
   Daneshvar, Daniel
   Katz, Douglas
   Mez, Jesse
   Goldstein, Lee
   Alosco, Michael
   Kowall, Neil
   Stern, Robert
   Stein, Thor
   Tripodis, Yorghos
   

   PMID: 38445389; PMCID: PMC11339554; DOI: 10.1089/neu.2023.0391;
7. Wang Y, Huang J, Ang TFA, Zhu Y, Tao Q, Mez J, Alosco M, Denis GV, Belkina A, Gurnani A, Ross M, Gong B, Han J, Lunetta KL, Stein TD, Au R, Farrer LA, Zhang X, Qiu WQ. The association between circulating CD34+CD133+ endothelial progenitor cells and reduced risk of Alzheimer's disease in the Framingham Heart Study. Explor Med. 2024; 5(2):193-214.View Related Profiles.

   Belkina, Anna
   Gurnani, Ashita
   Denis, Gerald
   Mez, Jesse
   Lunetta, Kathryn
   Farrer, Lindsay
   Alosco, Michael
   Tao, Qiushan
   Au, Rhoda
   Stein, Thor
   Ang, Ting Fang Alvin
   

   PMID: 38854406; PMCID: PMC11160969; DOI: 10.37349/emed.2024.00216;
8. Arciniega H, Baucom ZH, Tuz-Zahra F, Tripodis Y, John O, Carrington H, Kim N, Knyazhanskaya EE, Jung LB, Breedlove K, Wiegand TLT, Daneshvar DH, Rushmore RJ, Billah T, Pasternak O, Coleman MJ, Adler CH, Bernick C, Balcer LJ, Alosco ML, Koerte IK, Lin AP, Cummings JL, Reiman EM, Stern RA, Shenton ME, Bouix S. Brain morphometry in former American football players: Findings from the DIAGNOSE CTE research project. Brain. 2024 Mar 27.View Related Profiles.

   Daneshvar, Daniel
   Alosco, Michael
   Rushmore, Richard
   Stern, Robert
   Tripodis, Yorghos
   

   PMID: 38533783
9. Alosco ML, Tartaglia MC. Repetitive Blast Injury and CSF Alzheimer Disease Biomarkers: Navigating a Complex Narrative. Neurology. 2024 Apr 09; 102(7):e209294. PMID: 38478855
10. Banks SJ, Yhang E, Tripodis Y, Su Y, Protas H, Adler CH, Balcer LJ, Bernick C, Mez JB, Palmisano J, Barr WB, Wethe JV, Dodick DW, Mcclean MD, Martin B, Hartlage K, Turner A, Turner RW, Malhotra A, Colman M, Pasternak O, Lin AP, Koerte IK, Bouix S, Cummings JL, Shenton ME, Reiman EM, Stern RA, Alosco ML. Clinical Outcomes and Tau Pathology in Retired Football Players: Associations With Diagnosed and Witnessed Sleep Apnea. Neurol Clin Pract. 2024 Apr; 14(2):e200263.View Related Profiles.

    Mez, Jesse
    Alosco, Michael
    McClean, Michael
    Stern, Robert
    Tripodis, Yorghos
    

    PMID: 38425491; PMCID: PMC10900387; DOI: 10.1212/CPJ.0000000000200263;

Showing 10 of 213 results. Show More

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Former Pro Football Players Show Troubling Brain Changes

Study of former football players shows brain changes

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AAN study reveals Brain Lesions in Former Football Players Linked to Vascular, Brain Changes

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Football linked to more brain damage beyond white matter marks

Changes in the Diagnostic Process of Alzheimer Disease: A New Era of Blood-Based Approaches

Can Playing Football Increase Parkinson’s Risk?

Heads up: Concussions are common in soccer — especially for girls — but rules are changing to keep young athletes safe

Playing football can increase risk of Parkinson’s. Would you let your child play?

Playing Football Linked to Higher Parkinson's Risk

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Playing Football Linked to Higher Parkinson's Risk

Playing football may increase risk of Parkinson’s disease, study suggests

Playing tackle football may raise the risk for Parkinson’s disease: Boston University CTE Center

Playing football may increase risk for Parkinson's disease, study says

Playing Football Might Raise Parkinson's Risk

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Football players at increased risk for Parkinson's disease, study finds

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Playing Football Might Raise Parkinson's Risk

Playing Football May Increase the Risk for Developing Parkinson’s Disease

Playing tackle football at an early age increases risk for brain decline later

Long football careers linked to impulsive behavior, less white matter in the brain: Boston University CTE study

New BU Study Finds Tackle Football at Young Age Raises Risk for Brain Decline Later

Former Bronco plans to donate brain for concussion research: "If they want my brain they can have it"

Alzheimer's: Could beer hop compounds help reduce toxic clumps?

CTE: The Mysterious Brain Disorder That’s Taken Over the NFL

Boston University Researchers Study Contact Sports' Impact On Brains

Kraken broadcaster JT Brown said he plans to donate his brain to CTE research

White Matter Hyperintensities Linked to Repetitive Head Trauma

Could Structural MRI Findings Help Detect CTE During Life?

MRI Might Spot Concussion-Linked CTE in Living Patients

MRI Might Spot Concussion-Linked CTE in Living Patient

MRI Key to Diagnosing CTE in Living Patients?

More Years Playing Football, More Brain Lesions on MRI: Study

More Years Playing Football, More Brain Lesions on MRI: Study

Men who were in boxing clubs as youngsters may be THREE times as likely to develop Alzheimer's disease, study warns

Post-TBI Cognitive Changes 'Strikingly' Similar to Early Parkinson's

Researchers receive $460,000 NIH grant for brain imaging study

Repeated Head Impact Linked With Emotional, Cognitive Problems Later in Life

Repetitive Hits to the Head Tied To Depression, Poor Cognition in Later Life

Repeat Head Impacts May Lead to Depression Later

Repeated head impacts, brain injury increase risk for depression

Hype or horror? The risk of CTE brain disease divides football and medical communities

Ex-NFL Players Six Times More Likely than the General Public to Report Cognitive Problems, Study Finds

Rochester Woman Advocates for Alzheimer's Caregivers

Deeper Dive Into CTE, Dementia in Football Reveals New Players

What Years of Playing Football Does to Brain’s White Matter

Triple Threat: Tau, Atrophy, and Arteriolosclerosis Push CTE Toward Dementia

Five New Answers About the Link Between Football, CTE, and Dementia

Football Head Trauma Linked Again to Long-Term Brain Damage

Dementia Tied to White Matter Rarefaction in Football Players With CTE

Football Head Trauma Linked Again to Long-Term Brain Damage

On the Precipice of Memory Loss: Pursuing Better Diagnostic Tools for Patients with CTE and Other Neurodegenerative Disorders

Dementia-related marker found in former pro athletes with concussion history

For Patients With Memory Loss, Working Towards Better Diagnosis

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How A Massachusetts Bill Could Affect Local Pop Warner Teams

California bill would limit tackling during youth practices. Why it has leagues’ support

Subconcussive Head Impacts Alter Oculomotor Responses

Can Playing Football Lead Your Child To Develop a Disability?

Starting tackle football early sets kids up for brain problems

MED Researchers: Youth Football Linked to Earlier Brain Problems

Playing tackle footall before 12 can lead to long-term consequences