Michael Alosco, PhD
Associate Professor
Boston University Chobanian & Avedisian School of Medicine
Neurology

PhD, Kent State University
MA, Kent State University
BA, Providence College



Dr. Alosco is a licensed clinical neuropsychologist and serves as the co-director of the Boston University Alzheimer’s Disease Research Center Clinical Core and is a lead investigator of the BU CTE Center. He also oversees Neuropsychology for the Memory and Aging Clinic at Boston Medical Center. He completed his undergraduate studies at Providence College and he earned his doctoral degree in clinical psychology, with a focus on neuropsychology, in 2015 from Kent State University. He completed his clinical internship in neuropsychology at the VA Boston Healthcare System. Dr. Alosco completed his post-doctoral studies in neuropsychology via NIH-funded training Awards (T32, F32) at the Boston University Alzheimer’s Disease Research Center and CTE Center. In 2018, he became an Assistant Professor of Neurology at the Chobanian and Avedisian School of Medicine and he was promoted to Associate Professor in 2019. Dr. Alosco has >150 peer-reviewed publications, is the PI of multiple NIH funded grants, is the recipient of an NIH/NINDS K23 Award, is the Project Lead of an NIH-funded multisite U54 grant, and serves as aco-investigator on numerous federal and non-federal funded grants. He has also written numerous book chapters, and he is the co-Editor of the Oxford Handbook of Adult Cognitive Disorders which was published by Oxford University Press in 2019.

Dr. Alosco has an active and established research program that has a thematic focus on three areas: (1) the relationship between repetitive head impacts (RHI) and traumatic brain injury (TBI) with a later-life cognitive and neuropsychiatric decline, as well as neurodegenerative disease(s); (2) the contribution of cerebrovascular disease to the clinical and neuropathological expression of CTE, AD, and AD-related dementias (ADRD); and (3) in vivo biomarker development for CTE, AD, and ADRD with a focus on tau PET imaging, structural MRI, and blood-based biomarkers.


The Contribution of Repetitive Head Impacts and Social Determinants of Health to Brain Aging in Older Adult Black Men
08/15/2023 - 07/31/2028 (Subcontract PI)
The George Washington University NIH NINDS
1R01NS134043-01

Neuroimaging Research for Veterans (NeRVe) Center - Service Contract
08/01/2023 - 07/31/2028 (Multi-PI)
PI: Michael Alosco, PhD
VA Boston Healthcare System


Validation of Lens Beta-Amyloid as a Novel Biomarker for Early Detection of Alzheimer's Disease at the Boston University Alzheimer's Disease Research
09/30/2023 - 06/30/2028 (Multi-PI)
PI: Michael Alosco, PhD
NIH/National Institute on Aging
1R01AG077588-01A1

Boston University Alzheimer's Disease Research Center
08/15/2021 - 06/30/2026 (Key Person)
PI: Ann C. McKee, MD
NIH/National Institute on Aging
5P30AG072978-03

Risk for Later-Life Cognitive Impairment, Neurobehavioral Dysregulation, and Dementia in Former Soccer and American Football Players: The Head Impact and Trauma Surveillance Study (HITSS)
02/01/2021 - 01/31/2026 (PI)
NIH/National Institute of Neurological Disorders & Stroke
5R01NS119651-04

Blood Biomarker Development and Validation in Chronic Traumatic Encephalopathy and Alzheimer's Disease and Alzheimer's Disease Related Dementias
06/01/2023 - 05/31/2025 (Multi-PI)
PI: Michael Alosco, PhD
NIH/National Institute of Neurological Disorders & Stroke
1RF1NS132290-01

18F-PI-2620 Tau PET as a Biomarker for Chronic Traumatic Encephalopathy
03/15/2023 - 12/31/2024 (PI)
Life Molecular Imaging Ltd


The 1988 NFL Survey Study
12/15/2023 - 12/14/2024 (PI)
ESPN Productions, Inc.


Late Pathologies of Exposure to Repetitive Head Impacts from Contact Sports: White Matter and Vascular Contributions to Cognitive Impairment, Dementia, and Neuropsychiatric Symptoms
09/15/2021 - 08/31/2024 (Multi-PI)
PI: Michael Alosco, PhD
NIH/National Institute of Neurological Disorders & Stroke
1RF1NS122854-01

Alzheimer's Disease Neuroimaging Initiative 4 (ADNI 4)
09/15/2022 - 07/31/2024 (Subcontract PI)
University of Southern California NIH NIA
5U19AG024904-17

Showing 10 of 15 results. Show All Results


Title


Yr Title Project-Sub Proj Pubs
2024 Risk for Later-Life Cognitive Impairment, Neurobehavioral Dysregulation, and Dementia in Former Soccer and American Football Players: The Head Impact and Trauma Surveillance Study (HITSS) 5R01NS119651-04
2023 Validation of Lens Beta-Amyloid as a Novel Biomarker for Early Detection of Alzheimer's Disease at the Boston University Alzheimer's Disease Research 1R01AG077588-01A1
2023 Blood Biomarker Development and Validation in Chronic Traumatic Encephalopathy and Alzheimer's Disease and Alzheimer's Disease Related Dementias 1RF1NS132290-01
2023 Contributions of Exposure to Traumatic Brain Injury and Repetitive Head Impacts to Alzheimer's Disease and Related Dementias and Chronic Traumatic Encephalopathy 5U54NS115266-05-6542
2022 In Vivo Detection of Chronic Traumatic Encephalopathy with 18F-MK-6240 Tau PET 5R21NS120629-02
2022 Contributions of Exposure to Traumatic Brain Injury and Repetitive Head Impacts to Alzheimer's Disease and Related Dementias and Chronic Traumatic Encephalopathy 5U54NS115266-04-6600
2022 Repetitive Head Impact Exposure and Later-Life White Matter Signal Abnormalities: An Investigation in Former NFL Players, Subjects with Alzheimer's Disease, and Cognitively Normal Controls 5K23NS102399-05
2021 Late Pathologies of Exposure to Repetitive Head Impacts from Contact Sports: White Matter and Vascular Contributions to Cognitive Impairment, Dementia, and Neuropsychiatric Symptoms 1RF1NS122854-01
2021 In Vivo Detection of Chronic Traumatic Encephalopathy with 18F-MK-6240 Tau PET 1R21NS120629-01
2021 Contributions of Exposure to Traumatic Brain Injury and Repetitive Head Impacts to Alzheimer's Disease and Related Dementias and Chronic Traumatic Encephalopathy 5U54NS115266-03-6600
Showing 10 of 19 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Culhane JE, Jackson CE, Tripodis Y, Nowinski CJ, Dams-O'Connor K, Pettway E, Uretsky M, Abdolmohammadi B, Nair E, Martin B, Palmisano J, Katz DI, Dwyer B, Daneshvar DH, Goldstein LE, Kowall NW, Cantu RC, Stern RA, Huber BR, Crary JF, Mez J, Stein TD, McKee AC, Alosco ML. Lack of Association of Informant-Reported Traumatic Brain Injury and Chronic Traumatic Encephalopathy. J Neurotrauma. 2024 Apr 15.View Related Profiles. PMID: 38445389
     
  2. Arciniega H, Baucom ZH, Tuz-Zahra F, Tripodis Y, John O, Carrington H, Kim N, Knyazhanskaya EE, Jung LB, Breedlove K, Wiegand TLT, Daneshvar DH, Rushmore RJ, Billah T, Pasternak O, Coleman MJ, Adler CH, Bernick C, Balcer LJ, Alosco ML, Koerte IK, Lin AP, Cummings JL, Reiman EM, Stern RA, Shenton ME, Bouix S. Brain morphometry in former American football players: Findings from the DIAGNOSE CTE research project. Brain. 2024 Mar 27.View Related Profiles. PMID: 38533783
     
  3. Alosco ML, Tartaglia MC. Repetitive Blast Injury and CSF Alzheimer Disease Biomarkers: Navigating a Complex Narrative. Neurology. 2024 Apr 09; 102(7):e209294. PMID: 38478855
     
  4. Alexander A, Alvarez VE, Huber BR, Alosco ML, Mez J, Tripodis Y, Nicks R, Katz DI, Dwyer B, Daneshvar DH, Martin B, Palmisano J, Goldstein LE, Crary JF, Nowinski C, Cantu RC, Kowall NW, Stern RA, Delalle I, McKee AC, Stein TD. Cortical-sparing chronic traumatic encephalopathy (CSCTE): a distinct subtype of CTE. Acta Neuropathol. 2024 Feb 26; 147(1):45.View Related Profiles. PMID: 38407651
     
  5. Banks SJ, Yhang E, Tripodis Y, Su Y, Protas H, Adler CH, Balcer LJ, Bernick C, Mez JB, Palmisano J, Barr WB, Wethe JV, Dodick DW, Mcclean MD, Martin B, Hartlage K, Turner A, Turner RW, Malhotra A, Colman M, Pasternak O, Lin AP, Koerte IK, Bouix S, Cummings JL, Shenton ME, Reiman EM, Stern RA, Alosco ML. Clinical Outcomes and Tau Pathology in Retired Football Players: Associations With Diagnosed and Witnessed Sleep Apnea. Neurol Clin Pract. 2024 Apr; 14(2):e200263.View Related Profiles. PMID: 38425491; PMCID: PMC10900387; DOI: 10.1212/CPJ.0000000000200263;
     
  6. van Amerongen S, Pulukuri SV, Tuz-Zahra F, Tripodis Y, Cherry JD, Bernick C, Geda YE, Wethe JV, Katz DI, Alosco ML, Adler CH, Balcer LJ, Ashton NJ, Blennow K, Zetterberg H, Daneshvar DH, Colasurdo EA, Iliff JJ, Li G, Peskind ER, Shenton ME, Reiman EM, Cummings JL, Stern RA. Inflammatory biomarkers for neurobehavioral dysregulation in former American football players: findings from the DIAGNOSE CTE Research Project. J Neuroinflammation. 2024 Feb 09; 21(1):46.View Related Profiles. PMID: 38336728; PMCID: PMC10854026; DOI: 10.1186/s12974-024-03034-6;
     
  7. Alosco ML, White M, Bell C, Faheem F, Tripodis Y, Yhang E, Baucom Z, Martin B, Palmisano J, Dams-O'Connor K, Crary JF, Goldstein LE, Katz DI, Dwyer B, Daneshvar DH, Nowinski C, Cantu RC, Kowall NW, Stern RA, Alvarez VE, Huber BR, Stein TD, McKee AC, Mez J. Cognitive, functional, and neuropsychiatric correlates of regional tau pathology in autopsy-confirmed chronic traumatic encephalopathy. Mol Neurodegener. 2024 Feb 06; 19(1):10.View Related Profiles. PMID: 38317248; PMCID: PMC10845638; DOI: 10.1186/s13024-023-00697-2;
     
  8. Montoliu-Gaya L, Alosco ML, Yhang E, Tripodis Y, Sconzo D, Ally M, Grötschel L, Ashton NJ, Lantero-Rodriguez J, Sauer M, Gomes B, Nilsson J, Brinkmalm G, Sugarman MA, Aparicio HJ, Martin B, Palmisano JN, Steinberg EG, Simkin I, Turk KW, Budson AE, Au R, Farrer L, Jun GR, Kowall NW, Stern RA, Goldstein LE, Qiu WQ, Mez J, Huber BR, Alvarez VE, McKee AC, Zetterberg H, Gobom J, Stein TD, Blennow K. Optimal blood tau species for the detection of Alzheimer's disease neuropathology: an immunoprecipitation mass spectrometry and autopsy study. Acta Neuropathol. 2023 Dec 30; 147(1):5.View Related Profiles. PMID: 38159140; PMCID: PMC10757700; DOI: 10.1007/s00401-023-02660-3;
     
  9. Su Y, Protas H, Luo J, Chen K, Alosco ML, Adler CH, Balcer LJ, Bernick C, Au R, Banks SJ, Barr WB, Coleman MJ, Dodick DW, Katz DI, Marek KL, McClean MD, McKee AC, Mez J, Daneshvar DH, Palmisano JN, Peskind ER, Turner RW, Wethe JV, Rabinovici G, Johnson K, Tripodis Y, Cummings JL, Shenton ME, Stern RA, Reiman EM. Flortaucipir tau PET findings from former professional and college American football players in the DIAGNOSE CTE research project. Alzheimers Dement. 2024 Mar; 20(3):1827-1838.View Related Profiles. PMID: 38134231; PMCID: PMC10984430; DOI: 10.1002/alz.13602;
     
  10. Ly MT, Tuz-Zahra F, Tripodis Y, Adler CH, Balcer LJ, Bernick C, Zetterberg H, Blennow K, Peskind ER, Au R, Banks SJ, Barr WB, Wethe JV, Bondi MW, Delano-Wood LM, Cantu RC, Coleman MJ, Dodick DW, McClean MD, Mez JB, Palmisano J, Martin B, Hartlage K, Lin AP, Koerte IK, Cummings JL, Reiman EM, Shenton ME, Stern RA, Bouix S, Alosco ML. Association of Vascular Risk Factors and CSF and Imaging Biomarkers With White Matter Hyperintensities in Former American Football Players. Neurology. 2024 Jan 23; 102(2):e208030.View Related Profiles. PMID: 38165330; PMCID: PMC10870736; DOI: 10.1212/WNL.0000000000208030;
     
Showing 10 of 206 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 206 publications over 15 distinct years, with a maximum of 25 publications in 2013 and 2023

YearPublications
20104
20115
201213
201325
201424
201511
201614
201711
201811
201912
202013
202115
202216
202325
20247


BU researchers publish ‘crucial’ study that could help diagnose CTE before death

Boston.com 2/6/2024

Researchers get closer to diagnosing CTE in living patients

Futurity 2/6/2024

New Findings in Football Players May Aid the Future Diagnosis and Study of Chronic Traumatic Encephalopathy (CTE)

NIH Director's Blog 1/18/2024

What MRI-Derived Data and Other Factors Reveal About White Matter Hyperintensity in Former Football Players

Diagnostic Imaging 12/23/2023

Former Pro Football Players Show Troubling Brain Changes

Health Day 12/21/2023

Study of former football players shows brain changes

UPI 12/21/2023

Former Pro Football Players Show Troubling Brain Changes

US News & World Report 12/21/2023

AAN study reveals Brain Lesions in Former Football Players Linked to Vascular, Brain Changes

Business This Week 12/21/2023

Study of former football players shows brain changes

UPI 12/21/2023

Football linked to more brain damage beyond white matter marks

News Medical 12/20/2023

Changes in the Diagnostic Process of Alzheimer Disease: A New Era of Blood-Based Approaches

HCP Live 12/8/2023

Can Playing Football Increase Parkinson’s Risk?

The Good Men Project 9/17/2023

Heads up: Concussions are common in soccer — especially for girls — but rules are changing to keep young athletes safe

The Boston Globe 9/3/2023

Playing football can increase risk of Parkinson’s. Would you let your child play?

Boston.com 8/17/2023

Playing Football Linked to Higher Parkinson's Risk

Medscape 8/15/2023

Can playing football increase Parkinson’s risk?

Futurity 8/15/2023

Playing Football Linked to Higher Parkinson's Risk

Medscape 8/15/2023

Playing football may increase risk of Parkinson’s disease, study suggests

The Philadelphia Tribune 8/14/2023

Playing tackle football may raise the risk for Parkinson’s disease: Boston University CTE Center

Boston Herald 8/12/2023

Playing football may increase risk for Parkinson's disease, study says

UPI 8/11/2023

Playing Football Might Raise Parkinson's Risk

Health Day 8/11/2023

Playing Football Linked to Increased Parkinson's Ris

News Max 8/11/2023

Football players at increased risk for Parkinson's disease, study finds

News Medical 8/11/2023

Playing football may increase risk of Parkinson’s disease, study suggests

CNN 8/11/2023

Playing Football Might Raise Parkinson's Risk

US News & World Report 8/11/2023

Playing Football May Increase the Risk for Developing Parkinson’s Disease

BU Today 8/11/2023

Playing tackle football at an early age increases risk for brain decline later

News Medical 3/20/2023

Long football careers linked to impulsive behavior, less white matter in the brain: Boston University CTE study

Boston Herald 3/7/2023

New BU Study Finds Tackle Football at Young Age Raises Risk for Brain Decline Later

The Brink 3/6/2023

Former Bronco plans to donate brain for concussion research: "If they want my brain they can have it"

CBS News 12/8/2022

Alzheimer's: Could beer hop compounds help reduce toxic clumps?

Medical News Today 11/11/2022

CTE: The Mysterious Brain Disorder That’s Taken Over the NFL

Radio Health Journal 5/1/2022

Boston University Researchers Study Contact Sports' Impact On Brains

WBZ News Radio 3/8/2022

Kraken broadcaster JT Brown said he plans to donate his brain to CTE research

KOMO News 2/22/2022

White Matter Hyperintensities Linked to Repetitive Head Trauma

Neurology Today 12/16/2021

Could Structural MRI Findings Help Detect CTE During Life?

Diagnostic Imaging 12/16/2021

MRI Might Spot Concussion-Linked CTE in Living Patients

US News & World Report 12/8/2021

MRI Might Spot Concussion-Linked CTE in Living Patient

Health Day 12/8/2021

MRI Key to Diagnosing CTE in Living Patients?

Medscape 12/7/2021

More Years Playing Football, More Brain Lesions on MRI: Study

Health Day 11/29/2021

More Years Playing Football, More Brain Lesions on MRI: Study

US News & World Report 11/29/2021

Men who were in boxing clubs as youngsters may be THREE times as likely to develop Alzheimer's disease, study warns

Daily Mail 11/28/2021

Post-TBI Cognitive Changes 'Strikingly' Similar to Early Parkinson's

Medscape 11/22/2021

Researchers receive $460,000 NIH grant for brain imaging study

News Medical 1/19/2021

Repeated Head Impact Linked With Emotional, Cognitive Problems Later in Life

Psych Congress Network 7/13/2020

Repetitive Hits to the Head Tied To Depression, Poor Cognition in Later Life

Medscape 7/9/2020

Repeat Head Impacts May Lead to Depression Later

Futurity 6/30/2020

Repeated head impacts, brain injury increase risk for depression

UPI 6/26/2020

Hype or horror? The risk of CTE brain disease divides football and medical communities

Fox News 3/4/2020

Ex-NFL Players Six Times More Likely than the General Public to Report Cognitive Problems, Study Finds

The Boston Globe 8/30/2019

Rochester Woman Advocates for Alzheimer's Caregivers

The Union Leader 8/22/2019

Deeper Dive Into CTE, Dementia in Football Reveals New Players

Medscape 8/12/2019

What Years of Playing Football Does to Brain’s White Matter

Futurity 8/12/2019

Triple Threat: Tau, Atrophy, and Arteriolosclerosis Push CTE Toward Dementia

Alzforum 8/9/2019

Five New Answers About the Link Between Football, CTE, and Dementia

BU Today 8/5/2019

Football Head Trauma Linked Again to Long-Term Brain Damage

Health Day 8/5/2019

Dementia Tied to White Matter Rarefaction in Football Players With CTE

MedPage Today 8/5/2019

Football Head Trauma Linked Again to Long-Term Brain Damage

U.S. News & World Report 8/5/2019

On the Precipice of Memory Loss: Pursuing Better Diagnostic Tools for Patients with CTE and Other Neurodegenerative Disorders

Genetic Literacy Project 6/13/2019

Dementia-related marker found in former pro athletes with concussion history

Reuters 5/8/2019

For Patients With Memory Loss, Working Towards Better Diagnosis

Undark 5/6/2019

Free Event for Caregivers

Carriage Towne News 4/24/2019

How A Massachusetts Bill Could Affect Local Pop Warner Teams

Newport RI 3/5/2019

California bill would limit tackling during youth practices. Why it has leagues’ support

The Sacramento Bee 1/15/2019

Subconcussive Head Impacts Alter Oculomotor Responses

Reuters Health 12/26/2018

Can Playing Football Lead Your Child To Develop a Disability?

Ruderman Family Foundation 11/5/2018

Starting tackle football early sets kids up for brain problems

Futurity 5/2/2018

MED Researchers: Youth Football Linked to Earlier Brain Problems

BU Today 4/30/2018

Playing tackle footall before 12 can lead to long-term consequences

WCVB ABC 5 4/30/2018

2014 Kent State University: David B. Smith Award: Recognition Award for the most outstanding graduate student at Kent State U.
2014 Applied Psychology Center: Publication Award
2013 Applied Psychology Center: Publication Award
2012 American Psychological Association (APA): David Pilon Training Scholarship Award
2012 American Psychological Association (APA): Early Graduate Student Researcher Award
2011-2013 Graduate Student Senate at Kent State University: Domestic Travel Grant Award
2011-2013 Kent State University: Travel Award Applied Psychology Center
2011-2013 Kent State University: Student Travel Award, Department of Psychology
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Neurodegenerative conditions
cerebrovascular disease
head impacts
long-term neurological consequences
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