Neuroimaging Research for Veterans (NeRVe) Center - Service Contract
08/01/2023 - 07/31/2028 (Multi-PI)
PI: Michael Alosco, PhD
VA Boston Healthcare System


Boston University Alzheimer's Disease Research Center
08/15/2021 - 06/30/2026 (Key Person)
PI: Ann C. McKee, MD
NIH/National Institute on Aging
5P30AG072978-03

Risk for Later-Life Cognitive Impairment, Neurobehavioral Dysregulation, and Dementia in Former Soccer and American Football Players: The Head Impact and Trauma Surveillance Study (HITSS)
02/01/2021 - 01/31/2026 (PI)
NIH/National Institute of Neurological Disorders & Stroke
5R01NS119651-03

Blood Biomarker Development and Validation in Chronic Traumatic Encephalopathy and Alzheimer's Disease and Alzheimer's Disease Related Dementias
06/01/2023 - 05/31/2025 (Multi-PI)
PI: Michael Alosco, PhD
NIH/National Institute of Neurological Disorders & Stroke
1RF1NS132290-01

Late Pathologies of Exposure to Repetitive Head Impacts from Contact Sports: White Matter and Vascular Contributions to Cognitive Impairment, Dementia, and Neuropsychiatric Symptoms
09/15/2021 - 08/31/2024 (Multi-PI)
PI: Michael Alosco, PhD
NIH/National Institute of Neurological Disorders & Stroke
1RF1NS122854-01

18F-PI-2620 Tau PET as a Biomarker for Chronic Traumatic Encephalopathy
03/15/2023 - 05/13/2024 (PI)
Life Molecular Imaging Ltd


In Vivo Detection of Chronic Traumatic Encephalopathy with 18F-MK-6240 Tau PET
01/01/2021 - 12/31/2023 (PI)
The Regents of the University of California, San Francisco NIH NINDS
5R21NS120629-02

Alzheimer's Disease Neuroimaging Initiative 4 (ADNI 4)
09/15/2022 - 07/31/2023 (Subcontract PI)
University of Southern California NIH NIA
2U19AG024904-16

Human Tau Imaging
08/01/2020 - 07/31/2023 (Subcontract PI)
The Regents of the University of California, San Francisco Rainwater Char. Fdn


Repetitive Head Impact Exposure and Later-Life White Matter Signal Abnormalities: An Investigation in Former NFL Players, Subjects with Alzheimer's Disease, and Cognitively Normal Controls
08/01/2018 - 04/30/2023 (PI)
NIH/National Institute of Neurological Disorders & Stroke
5K23NS102399-05

Showing 10 of 12 results. Show All Results

1. Rosen G, Kirsch D, Horowitz S, Cherry JD, Nicks R, Kelley H, Uretsky M, Dell'Aquila K, Mathias R, Cormier KA, Kubilus CA, Mez J, Tripodis Y, Stein TD, Alvarez VE, Alosco ML, McKee AC, Huber BR. Three dimensional evaluation of cerebrovascular density and branching in chronic traumatic encephalopathy. Acta Neuropathol Commun. 2023 Jul 25; 11(1):123.View Related Profiles.

   McKee, Ann
   Huber, Bertrand
   Mez, Jesse
   Cherry, Jonathan
   Alosco, Michael
   Stein, Thor
   Alvarez, Victor
   Tripodis, Yorghos
   

   PMID: 37491342; PMCID: PMC10369801; DOI: 10.1186/s40478-023-01612-y;
2. Daneshvar DH, Nair ES, Baucom ZH, Rasch A, Abdolmohammadi B, Uretsky M, Saltiel N, Shah A, Jarnagin J, Baugh CM, Martin BM, Palmisano JN, Cherry JD, Alvarez VE, Huber BR, Weuve J, Nowinski CJ, Cantu RC, Zafonte RD, Dwyer B, Crary JF, Goldstein LE, Kowall NW, Katz DI, Stern RA, Tripodis Y, Stein TD, McClean MD, Alosco ML, McKee AC, Mez J. Leveraging football accelerometer data to quantify associations between repetitive head impacts and chronic traumatic encephalopathy in males. Nat Commun. 2023 Jun 20; 14(1):3470.View Related Profiles.

   McKee, Ann
   Huber, Bertrand
   Dwyer, Brigid
   Nowinski, Christopher
   Daneshvar, Daniel
   Katz, Douglas
   Weuve, Jennifer
   Mez, Jesse
   Cherry, Jonathan
   Goldstein, Lee
   Alosco, Michael
   McClean, Michael
   Kowall, Neil
   Stern, Robert
   Stein, Thor
   Alvarez, Victor
   Tripodis, Yorghos
   

   PMID: 37340004; PMCID: PMC10281995; DOI: 10.1038/s41467-023-39183-0;
3. Fang Y, Doyle MF, Chen J, Mez J, Satizabal CL, Alosco ML, Qiu WQ, Lunetta KL, Murabito JM. Circulating immune cell phenotypes are associated with age, sex, CMV, and smoking status in the Framingham Heart Study offspring participants. Aging (Albany NY). 2023 Apr 27; 15(10):3939-3966.View Related Profiles.

   Satizabal, Claudia
   Mez, Jesse
   Murabito, Joanne
   Lunetta, Kathryn
   Alosco, Michael
   Fang, Yuan
   

   PMID: 37116193; PMCID: PMC10258017; DOI: 10.18632/aging.204686;
4. Groechel RC, Tripodis Y, Alosco ML, Mez J, Qiu WQ, Mercier G, Goldstein L, Budson AE, Kowall NW, Killiany RJ. Annualized changes in rate of amyloid deposition and neurodegeneration are greater in participants who become amyloid positive than those who remain amyloid negative. Neurobiol Aging. 2023 Jul; 127:33-42.View Related Profiles.

   Budson, Andrew
   Mercier, Gustavo
   Mez, Jesse
   Alosco, Michael
   Kowall, Neil
   Tripodis, Yorghos
   

   PMID: 37043881
5. Alosco ML, Ly M, Mosaheb S, Saltiel N, Uretsky M, Tripodis Y, Martin B, Palmisano J, Delano-Wood L, Bondi MW, Meng G, Xia W, Daley S, Goldstein LE, Katz DI, Dwyer B, Daneshvar DH, Nowinski C, Cantu RC, Kowall NW, Stern RA, Alvarez VE, Mez J, Huber BR, McKee AC, Stein TD. Decreased myelin proteins in brain donors exposed to football-related repetitive head impacts. Brain Commun. 2023; 5(2):fcad019.View Related Profiles.

   McKee, Ann
   Huber, Bertrand
   Dwyer, Brigid
   Nowinski, Christopher
   Daneshvar, Daniel
   Katz, Douglas
   Mez, Jesse
   Goldstein, Lee
   Alosco, Michael
   Kowall, Neil
   Stern, Robert
   Stein, Thor
   Alvarez, Victor
   Tripodis, Yorghos
   

   PMID: 36895961; PMCID: PMC9990992; DOI: 10.1093/braincomms/fcad019;
6. McKee AC, Stein TD, Huber BR, Crary JF, Bieniek K, Dickson D, Alvarez VE, Cherry JD, Farrell K, Butler M, Uretsky M, Abdolmohammadi B, Alosco ML, Tripodis Y, Mez J, Daneshvar DH. Chronic traumatic encephalopathy (CTE): criteria for neuropathological diagnosis and relationship to repetitive head impacts. Acta Neuropathol. 2023 Apr; 145(4):371-394.View Related Profiles.

   McKee, Ann
   Huber, Bertrand
   Daneshvar, Daniel
   Mez, Jesse
   Cherry, Jonathan
   Alosco, Michael
   Stein, Thor
   Alvarez, Victor
   Tripodis, Yorghos
   

   PMID: 36759368; PMCID: PMC10020327; DOI: 10.1007/s00401-023-02540-w;
7. Nicks R, Clement NF, Alvarez VE, Tripodis Y, Baucom ZH, Huber BR, Mez J, Alosco ML, Aytan N, Cherry JD, Cormier KA, Kubilius C, Mathias R, Svirsky SE, Pothast MJ, Hildebrandt AM, Chung J, Han X, Crary JF, McKee AC, Frosch MP, Stein TD. Repetitive head impacts and chronic traumatic encephalopathy are associated with TDP-43 inclusions and hippocampal sclerosis. Acta Neuropathol. 2023 Apr; 145(4):395-408.View Related Profiles.

   McKee, Ann
   Huber, Bertrand
   Mez, Jesse
   Cherry, Jonathan
   Alosco, Michael
   Aytan, Nurgul
   Stein, Thor
   Alvarez, Victor
   Tripodis, Yorghos
   

   PMID: 36681782; DOI: 10.1007/s00401-023-02539-3;
8. Wang Y, Huang J, Ang TFA, Zhu Y, Tao Q, Mez J, Alosco M, Denis GV, Belkina A, Gurnani A, Ross M, Gong B, Han J, Lunetta KL, Stein TD, Au R, Farrer LA, Zhang X, Qiu WQ. Circulating Endothelial Progenitor Cells Reduce the Risk of Alzheimer's Disease. medRxiv. 2023 Jan 18.View Related Profiles.

   Belkina, Anna
   Gurnani, Ashita
   Denis, Gerald
   Mez, Jesse
   Lunetta, Kathryn
   Farrer, Lindsay
   Alosco, Michael
   Tao, Qiushan
   Au, Rhoda
   Stein, Thor
   

   PMID: 36711847; PMCID: PMC9882408; DOI: 10.1101/2023.01.16.23284571;
9. Alosco ML, Barr WB, Banks SJ, Wethe JV, Miller JB, Pulukuri SV, Culhane J, Tripodis Y, Adler CH, Balcer LJ, Bernick C, Mariani ML, Cantu RC, Dodick DW, McClean MD, Au R, Mez J, Turner RW, Palmisano JN, Martin B, Hartlage K, Cummings JL, Reiman EM, Shenton ME, Stern RA. Neuropsychological test performance of former American football players. Alzheimers Res Ther. 2023 Jan 03; 15(1):1.View Related Profiles.

   Mez, Jesse
   Alosco, Michael
   McClean, Michael
   Au, Rhoda
   Stern, Robert
   Tripodis, Yorghos
   

   PMID: 36597138; PMCID: PMC9808953; DOI: 10.1186/s13195-022-01147-9;
10. Vig V, Garg I, Tuz-Zahra F, Xu J, Tripodis Y, Nicks R, Xia W, Alvarez VE, Alosco ML, Stein TD, Subramanian ML. Vitreous Humor Biomarkers Reflect Pathological Changes in the Brain for Alzheimer's Disease and Chronic Traumatic Encephalopathy. J Alzheimers Dis. 2023; 93(3):1181-1193.View Related Profiles.

    Xu, Jia
    Subramanian, Manju
    Alosco, Michael
    Stein, Thor
    Alvarez, Victor
    Tripodis, Yorghos
    

    PMID: 37182888; PMCID: PMC10258881; DOI: 10.3233/JAD-230167;

Showing 10 of 184 results. Show More

Can Playing Football Increase Parkinson’s Risk?

Heads up: Concussions are common in soccer — especially for girls — but rules are changing to keep young athletes safe

Playing football can increase risk of Parkinson’s. Would you let your child play?

Playing Football Linked to Higher Parkinson's Risk

Can playing football increase Parkinson’s risk?

Playing Football Linked to Higher Parkinson's Risk

Playing football may increase risk of Parkinson’s disease, study suggests

Playing tackle football may raise the risk for Parkinson’s disease: Boston University CTE Center

Playing football may increase risk for Parkinson's disease, study says

Playing Football Might Raise Parkinson's Risk

Playing Football Linked to Increased Parkinson's Ris

Football players at increased risk for Parkinson's disease, study finds

Playing football may increase risk of Parkinson’s disease, study suggests

Playing Football Might Raise Parkinson's Risk

Playing Football May Increase the Risk for Developing Parkinson’s Disease

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Playing tackle football at an early age increases risk for brain decline later

Long football careers linked to impulsive behavior, less white matter in the brain: Boston University CTE study

New BU Study Finds Tackle Football at Young Age Raises Risk for Brain Decline Later

Former Bronco plans to donate brain for concussion research: "If they want my brain they can have it"

Alzheimer's: Could beer hop compounds help reduce toxic clumps?

CTE: The Mysterious Brain Disorder That’s Taken Over the NFL

Boston University Researchers Study Contact Sports' Impact On Brains

Kraken broadcaster JT Brown said he plans to donate his brain to CTE research

White Matter Hyperintensities Linked to Repetitive Head Trauma

Could Structural MRI Findings Help Detect CTE During Life?

MRI Might Spot Concussion-Linked CTE in Living Patients

MRI Might Spot Concussion-Linked CTE in Living Patient

MRI Key to Diagnosing CTE in Living Patients?

More Years Playing Football, More Brain Lesions on MRI: Study

More Years Playing Football, More Brain Lesions on MRI: Study

Men who were in boxing clubs as youngsters may be THREE times as likely to develop Alzheimer's disease, study warns

Post-TBI Cognitive Changes 'Strikingly' Similar to Early Parkinson's

Researchers receive $460,000 NIH grant for brain imaging study

Repeated Head Impact Linked With Emotional, Cognitive Problems Later in Life

Repetitive Hits to the Head Tied To Depression, Poor Cognition in Later Life

Repeat Head Impacts May Lead to Depression Later

Repeated head impacts, brain injury increase risk for depression

Hype or horror? The risk of CTE brain disease divides football and medical communities

Ex-NFL Players Six Times More Likely than the General Public to Report Cognitive Problems, Study Finds

Rochester Woman Advocates for Alzheimer's Caregivers

Deeper Dive Into CTE, Dementia in Football Reveals New Players

What Years of Playing Football Does to Brain’s White Matter

Triple Threat: Tau, Atrophy, and Arteriolosclerosis Push CTE Toward Dementia

Five New Answers About the Link Between Football, CTE, and Dementia

Football Head Trauma Linked Again to Long-Term Brain Damage

Dementia Tied to White Matter Rarefaction in Football Players With CTE

Football Head Trauma Linked Again to Long-Term Brain Damage

On the Precipice of Memory Loss: Pursuing Better Diagnostic Tools for Patients with CTE and Other Neurodegenerative Disorders

Dementia-related marker found in former pro athletes with concussion history

For Patients With Memory Loss, Working Towards Better Diagnosis

Free Event for Caregivers

How A Massachusetts Bill Could Affect Local Pop Warner Teams

California bill would limit tackling during youth practices. Why it has leagues’ support

Subconcussive Head Impacts Alter Oculomotor Responses

Can Playing Football Lead Your Child To Develop a Disability?

Starting tackle football early sets kids up for brain problems

MED Researchers: Youth Football Linked to Earlier Brain Problems

Playing tackle footall before 12 can lead to long-term consequences