Michael Alosco, PhD
Associate Professor
Boston University School of Medicine
Dept of Neurology

PhD, Kent State University
MA, Kent State University




Dr. Alosco completed his undergraduate studies at Providence College and he earned his doctoral degree in clinical psychology, with a focus in neuropsychology, in 2015 from Kent State University. He completed his clinical internship in neuropsychology at the VA Boston Healthcare System. In 2015, Dr. Alosco was awarded a post-doctoral fellowship at the Boston University (BU) Alzheimer’s Disease (AD) Center (ADC) and BU CTE Center through the NIA-funded Alzheimer’s Disease Translational Research Training Program (T32AG036697). In 2016, Dr. Alosco transitioned to a National Research Service Award (NRSA) F32 from the National Institute of Neurological Disorders and Stroke to continue his advanced clinical research training at the BU ADC and BU CTE Center. In 2018, he became an Assistant Professor of Neurology at the Boston University School of Medicine.

Dr. Alosco’s research focuses on risk factors and biomarkers of neurodegenerative conditions, with a focus on AD and CTE. Dr. Alosco is particularly interested in the contribution of cerebrovascular disease to the clinical and neuropathological presentation of AD and CTE. He is additionally involved in research examining the relationship between exposure to repetitive head impacts and long-term neurological consequences. He is mentored at the BU AD and CTE Center by Robert A. Stern, Ph.D., and Ann C. McKee, M.D.

In August 2018, he received a five-year K23 Award from the National Institutes of Health’s National Institute of Neurological Disorders and Stroke (NINDS). He will use MRI data and biomarkers to examine patterns of white matter alterations in former NFL players compared to healthy individuals as well as those with Alzheimer’s disease dementia. He will do so by leveraging ongoing studies at BUSM, including the NINDS-funded DIAGNOSE CTE Research Project and the National Institute on Aging (NIA) funded BU Alzheimer’s Disease Center (BU ADC). The K23 Award will additionally provide Dr. Alosco with advanced and cutting-edge training in CTE to facilitate his progression as an independent clinical neuroscientist.

2014 Kent State University: David B. Smith Award: Recognition Award for the most outstanding graduate student at Kent State U.
2014 Applied Psychology Center: Publication Award
2013 Applied Psychology Center: Publication Award
2012 American Psychological Association (APA): David Pilon Training Scholarship Award
2012 American Psychological Association (APA): Early Graduate Student Researcher Award
2011-2013 Graduate Student Senate at Kent State University: Domestic Travel Grant Award
2011-2013 Kent State University: Travel Award Applied Psychology Center
2011-2013 Kent State University: Student Travel Award, Department of Psychology


Repetitive Head Impact Exposure and Later-Life White Matter Signal Abnormalities: An Investigation in Former NFL Players, Subjects with Alzheimer's Disease, and Cognitively Normal Controls
08/01/2018 - 04/30/2023 (PI)
NIH/National Institute of Neurological Disorders & Stroke
5K23NS102399-03

Cerebral perfusion and metabolism in chronic traumatic encephalopathy
11/01/2017 - 10/31/2020 (PI)
The Brigham and Women's Hospital, Inc.


Magnetic Resonance Spectroscopy as a Biomarker for Chronic Traumatic Encephalopathy
05/01/2016 - 04/30/2018 (Multi-PI)
PI: Michael Alosco, PhD
NIH/National Institute of Neurological Disorders & Stroke
5F32NS096803-02



Title


Yr Title Project-Sub Proj Pubs
2021 In Vivo Detection of Chronic Traumatic Encephalopathy with 18F-MK-6240 Tau PET 1R21NS120629-01
2020 Contributions of Exposure to Traumatic Brain Injury and Repetitive Head Impacts to Alzheimer's Disease and Related Dementias and Chronic Traumatic Encephalopathy 5U54NS115266-02-6600
2020 Repetitive Head Impact Exposure and Later-Life White Matter Signal Abnormalities: An Investigation in Former NFL Players, Subjects with Alzheimer's Disease, and Cognitively Normal Controls 5K23NS102399-03 13
2019 Repetitive Head Impact Exposure and Later-Life White Matter Signal Abnormalities: An Investigation in Former NFL Players, Subjects with Alzheimer's Disease, and Cognitively Normal Controls 5K23NS102399-02 13
2019 Contributions of Exposure to Traumatic Brain Injury and Repetitive Head Impacts to Alzheimer's Disease and Related Dementias and Chronic Traumatic Encephalopathy 1U54NS115266-01-6600
2018 Repetitive Head Impact Exposure and Later-Life White Matter Signal Abnormalities: An Investigation in Former NFL Players, Subjects with Alzheimer's Disease, and Cognitively Normal Controls 1K23NS102399-01A1 13
2017 Magnetic Resonance Spectroscopy as a Biomarker for Chronic Traumatic Encephalopathy 3F32NS096803-01S1 22
2017 Magnetic Resonance Spectroscopy as a Biomarker for Chronic Traumatic Encephalopathy 5F32NS096803-02 22
2016 Magnetic Resonance Spectroscopy as a Biomarker for Chronic Traumatic Encephalopathy 1F32NS096803-01 22

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Cherry JD, Meng G, Daley S, Xia W, Svirsky S, Alvarez VE, Nicks R, Pothast M, Kelley H, Huber B, Tripodis Y, Alosco ML, Mez J, McKee AC, Stein TD. CCL2 is associated with microglia and macrophage recruitment in chronic traumatic encephalopathy. J Neuroinflammation. 2020 Dec 05; 17(1):370.View Related Profiles. PMID: 33278887; DOI: 10.1186/s12974-020-02036-4;
     
  2. Alosco ML, Tripodis Y, Rowland B, Chua AS, Liao H, Martin B, Jarnagin J, Chaisson CE, Pasternak O, Karmacharya S, Koerte IK, Cantu RC, Kowall NW, McKee AC, Shenton ME, Greenwald R, McClean M, Stern RA, Lin A. A magnetic resonance spectroscopy investigation in symptomatic former NFL players. Brain Imaging Behav. 2020 Oct; 14(5):1419-1429.View Related Profiles. PMID: 30848432; DOI: 10.1007/s11682-019-00060-4;
     
  3. Adams JW, Alosco ML, Mez J, Alvarez VE, Huber BR, Tripodis Y, Adler CH, Kubilius C, Cormier KA, Mathais R, Nicks R, Kelley HJ, Saltiel N, Uretsky M, Nair E, Aytan N, Cherry JD, Nowinski CJ, Kowall NW, Goldstein LE, Dwyer B, Katz DI, Cantu RC, Stern RA, McKee AC, Stein TD. Association of probable REM sleep behavior disorder with pathology and years of contact sports play in chronic traumatic encephalopathy. Acta Neuropathol. 2020 12; 140(6):851-862.View Related Profiles. PMID: 32939646
     
  4. Mez J, Daneshvar DH, Alosco ML, Alvarez VE, Huber BR, Stein TD, McKee AC. Reply to "Chronic Traumatic Encephalopathy and Primary Age-Related Tauopathy". Ann Neurol. 2020 11; 88(5):1052-1053.View Related Profiles. PMID: 32754941
     
  5. Alosco ML, Cherry JD, Huber BR, Tripodis Y, Baucom Z, Kowall NW, Saltiel N, Goldstein LE, Katz DI, Dwyer B, Daneshvar DH, Palmisano JN, Martin B, Cantu RC, Stern RA, Alvarez VE, Mez J, Stein TD, McKee AC. Characterizing tau deposition in chronic traumatic encephalopathy (CTE): utility of the McKee CTE staging scheme. Acta Neuropathol. 2020 10; 140(4):495-512.View Related Profiles. PMID: 32778942
     
  6. Mariani M, Alosco ML, Mez J, Stern RA. Clinical Presentation of Chronic Traumatic Encephalopathy. Semin Neurol. 2020 Aug; 40(4):370-383.View Related Profiles. PMID: 32740900
     
  7. Phelps A, Mez J, Stern RA, Alosco ML. Risk Factors for Chronic Traumatic Encephalopathy: A Proposed Framework. Semin Neurol. 2020 08; 40(4):439-449.View Related Profiles. PMID: 32674182
     
  8. Cherry JD, Kim SH, Stein TD, Pothast MJ, Nicks R, Meng G, Huber BR, Mez J, Alosco ML, Tripodis Y, Farrell K, Alvarez VE, McKee AC, Crary JF. Evolution of neuronal and glial tau isoforms in chronic traumatic encephalopathy. Brain Pathol. 2020 09; 30(5):913-925.View Related Profiles. PMID: 32500646; DOI: 10.1111/bpa.12867;
     
  9. Alosco ML, Tripodis Y, Baucom ZH, Mez J, Stein TD, Martin B, Haller O, Conneely S, McClean M, Nosheny R, Mackin S, McKee AC, Weiner MW, Stern RA. Late contributions of repetitive head impacts and TBI to depression symptoms and cognition. Neurology. 2020 08 18; 95(7):e793-e804.View Related Profiles. PMID: 32591472; DOI: 10.1212/WNL.0000000000010040;
     
  10. Sugarman MA, Zetterberg H, Blennow K, Tripodis Y, McKee AC, Stein TD, Martin B, Palmisano JN, Steinberg EG, Simkin I, Budson AE, Killiany R, O'Connor MK, Au R, Qiu WWQ, Goldstein LE, Kowall NW, Mez J, Stern RA, Alosco ML. A longitudinal examination of plasma neurofilament light and total tau for the clinical detection and monitoring of Alzheimer's disease. Neurobiol Aging. 2020 10; 94:60-70.View Related Profiles. PMID: 32585491; DOI: 10.1016/j.neurobiolaging.2020.05.011;
     
Showing 10 of 143 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 143 publications over 11 distinct years, with a maximum of 25 publications in 2013

YearPublications
20104
20115
201213
201325
201424
201511
201614
201711
201811
201912
202013


Recent (within 3 months)

Researchers receive $460,000 NIH grant for brain imaging study

News Medical 1/19/2021
Older

Repeated Head Impact Linked With Emotional, Cognitive Problems Later in Life

Psych Congress Network 7/13/2020

Repetitive Hits to the Head Tied To Depression, Poor Cognition in Later Life

Medscape 7/9/2020

Repeat Head Impacts May Lead to Depression Later

Futurity 6/30/2020

Repeated head impacts, brain injury increase risk for depression

UPI 6/26/2020

Hype or horror? The risk of CTE brain disease divides football and medical communities

Fox News 3/4/2020

Ex-NFL Players Six Times More Likely than the General Public to Report Cognitive Problems, Study Finds

The Boston Globe 8/30/2019

Rochester Woman Advocates for Alzheimer's Caregivers

The Union Leader 8/22/2019

Deeper Dive Into CTE, Dementia in Football Reveals New Players

Medscape 8/12/2019

What Years of Playing Football Does to Brain’s White Matter

Futurity 8/12/2019

Triple Threat: Tau, Atrophy, and Arteriolosclerosis Push CTE Toward Dementia

Alzforum 8/9/2019

Five New Answers About the Link Between Football, CTE, and Dementia

BU Today 8/5/2019

Football Head Trauma Linked Again to Long-Term Brain Damage

Health Day 8/5/2019

Dementia Tied to White Matter Rarefaction in Football Players With CTE

MedPage Today 8/5/2019

Football Head Trauma Linked Again to Long-Term Brain Damage

U.S. News & World Report 8/5/2019

On the Precipice of Memory Loss: Pursuing Better Diagnostic Tools for Patients with CTE and Other Neurodegenerative Disorders

Genetic Literacy Project 6/13/2019

Dementia-related marker found in former pro athletes with concussion history

Reuters 5/8/2019

For Patients With Memory Loss, Working Towards Better Diagnosis

Undark 5/6/2019

Free Event for Caregivers

Carriage Towne News 4/24/2019

How A Massachusetts Bill Could Affect Local Pop Warner Teams

Newport RI 3/5/2019

California bill would limit tackling during youth practices. Why it has leagues’ support

The Sacramento Bee 1/15/2019

Subconcussive Head Impacts Alter Oculomotor Responses

Reuters Health 12/26/2018

Can Playing Football Lead Your Child To Develop a Disability?

Ruderman Family Foundation 11/5/2018

Starting tackle football early sets kids up for brain problems

Futurity 5/2/2018

MED Researchers: Youth Football Linked to Earlier Brain Problems

BU Today 4/30/2018

Playing tackle footall before 12 can lead to long-term consequences

WCVB ABC 5 4/30/2018
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Neurodegenerative conditions
cerebrovascular disease
head impacts
long-term neurological consequences
Contact for Mentoring:

72 E. Concord Street
Boston MA 02118
Google Map

617.638.5351
Download vCard

Alosco's Networks
Click the "See All" links for more information and interactive visualizations
Concepts
See all (316) concept(s)
_
Media Mentions
_
Co-Authors
See all (48) people
_
Similar People
See all (60) people
_
Same Department
Search Department