Keywords
Last Name

Thor Stein, MD, PhD

TitleAssistant Professor
InstitutionBoston University School of Medicine
DepartmentPathology & Laboratory Medicine
Address150 S Huntington Avenue
Jamaica Plain MA 02130
Phone(617) 599-2684
ORCID ORCID Icon0000-0001-6954-4477
Other Positions
InstitutionVA Boston Healthcare System

 Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Hsieh T, Vaickus MH, Stein TD, Lussier BL, Kim J, Stepien DM, Duffy ER, Chiswick EL, Remick DG. The Role of Substance P in Pulmonary Clearance of Bacteria in Comparative Injury Models. Am J Pathol. 2016 Dec; 186(12):3236-3245. PMID: 27876152.
    View in: PubMed
  2. Cherry JD, Tripodis Y, Alvarez VE, Huber B, Kiernan PT, Daneshvar DH, Mez J, Montenigro PH, Solomon TM, Alosco ML, Stern RA, McKee AC, Stein TD. Microglial neuroinflammation contributes to tau accumulation in chronic traumatic encephalopathy. Acta Neuropathol Commun. 2016 Oct 28; 4(1):112. PMID: 27793189.
    View in: PubMed
  3. Alosco ML, Mez J, Kowall NW, Stein TD, Goldstein LE, Cantu RC, Katz DI, Solomon TM, Kiernan PT, Murphy L, Abdolmohammadi B, Daneshvar D, Montenigro PH, Nowinski CJ, Stern RA, McKee AC. Cognitive Reserve as a Modifier of Clinical Expression in Chronic Traumatic Encephalopathy: A Preliminary Examination. J Neuropsychiatry Clin Neurosci. 2017; 29(1):6-12. PMID: 27539377.
    View in: PubMed
  4. Armstrong RA, McKee AC, Stein TD, Alvarez VE, Cairns NJ. A quantitative study of tau pathology in 11 cases of chronic traumatic encephalopathy. Neuropathol Appl Neurobiol. 2017 Feb; 43(2):154-166. PMID: 26998921.
    View in: PubMed
  5. Mez J, Solomon TM, Daneshvar DH, Stein TD, McKee AC. Pathologically Confirmed Chronic Traumatic Encephalopathy in a 25-Year-Old Former College Football Player. JAMA Neurol. 2016 Mar; 73(3):353-5. PMID: 26747562.
    View in: PubMed
  6. Huber BR, Alosco ML, Stein TD, McKee AC. Potential Long-Term Consequences of Concussive and Subconcussive Injury. Phys Med Rehabil Clin N Am. 2016 May; 27(2):503-11. PMID: 27154859.
    View in: PubMed
  7. Kanaan NM, Cox K, Alvarez VE, Stein TD, Poncil S, McKee AC. Characterization of Early Pathological Tau Conformations and Phosphorylation in Chronic Traumatic Encephalopathy. J Neuropathol Exp Neurol. 2016 Jan; 75(1):19-34. PMID: 26671985.
    View in: PubMed
  8. McKee AC, Cairns NJ, Dickson DW, Folkerth RD, Keene CD, Litvan I, Perl DP, Stein TD, Vonsattel JP, Stewart W, Tripodis Y, Crary JF, Bieniek KF, Dams-O'Connor K, Alvarez VE, Gordon WA. The first NINDS/NIBIB consensus meeting to define neuropathological criteria for the diagnosis of chronic traumatic encephalopathy. Acta Neuropathol. 2016 Jan; 131(1):75-86. PMID: 26667418.
    View in: PubMed
  9. Mez J, Solomon TM, Daneshvar DH, Murphy L, Kiernan PT, Montenigro PH, Kriegel J, Abdolmohammadi B, Fry B, Babcock KJ, Adams JW, Bourlas AP, Papadopoulos Z, McHale L, Ardaugh BM, Martin BR, Dixon D, Nowinski CJ, Chaisson C, Alvarez VE, Tripodis Y, Stein TD, Goldstein LE, Katz DI, Kowall NW, Cantu RC, Stern RA, McKee AC. Assessing clinicopathological correlation in chronic traumatic encephalopathy: rationale and methods for the UNITE study. Alzheimers Res Ther. 2015; 7(1):62. PMID: 26455775.
    View in: PubMed
  10. Stein TD, Alvarez VE, McKee AC. Concussion in Chronic Traumatic Encephalopathy. Curr Pain Headache Rep. 2015 Oct; 19(10):47. PMID: 26260277.
    View in: PubMed
  11. Martinez-Ramirez S, Romero JR, Shoamanesh A, McKee AC, Van Etten E, Pontes-Neto O, Macklin EA, Ayres A, Auriel E, Himali JJ, Beiser AS, DeCarli C, Stein TD, Alvarez VE, Frosch MP, Rosand J, Greenberg SM, Gurol ME, Seshadri S, Viswanathan A. Diagnostic value of lobar microbleeds in individuals without intracerebral hemorrhage. Alzheimers Dement. 2015 Dec; 11(12):1480-8. PMID: 26079413.
    View in: PubMed
  12. Stein TD, Montenigro PH, Alvarez VE, Xia W, Crary JF, Tripodis Y, Daneshvar DH, Mez J, Solomon T, Meng G, Kubilus CA, Cormier KA, Meng S, Babcock K, Kiernan P, Murphy L, Nowinski CJ, Martin B, Dixon D, Stern RA, Cantu RC, Kowall NW, McKee AC. Beta-amyloid deposition in chronic traumatic encephalopathy. Acta Neuropathol. 2015 Jul; 130(1):21-34. PMID: 25943889.
    View in: PubMed
  13. McKee AC, Stein TD, Kiernan PT, Alvarez VE. The neuropathology of chronic traumatic encephalopathy. Brain Pathol. 2015 May; 25(3):350-64. PMID: 25904048.
    View in: PubMed
  14. Daneshvar DH, Goldstein LE, Kiernan PT, Stein TD, McKee AC. Post-traumatic neurodegeneration and chronic traumatic encephalopathy. Mol Cell Neurosci. 2015 May; 66(Pt B):81-90. PMID: 25758552.
    View in: PubMed
  15. Montenigro PH, Corp DT, Stein TD, Cantu RC, Stern RA. Chronic traumatic encephalopathy: historical origins and current perspective. Annu Rev Clin Psychol. 2015; 11:309-30. PMID: 25581233.
    View in: PubMed
  16. Stein TD, Alvarez VE, McKee AC. Chronic traumatic encephalopathy: a spectrum of neuropathological changes following repetitive brain trauma in athletes and military personnel. Alzheimers Res Ther. 2014; 6(1):4. PMID: 24423082.
    View in: PubMed
  17. Stein TD, Chae YS, Won N, Lee JH, Hedley-Whyte ET. A 34-year-old man with bitemporal hemianopsia. Brain Pathol. 2014 Jan; 24(1):107-10. PMID: 24345226.
    View in: PubMed
  18. McKee AC, Daneshvar DH, Alvarez VE, Stein TD. The neuropathology of sport. Acta Neuropathol. 2014 Jan; 127(1):29-51. PMID: 24366527.
    View in: PubMed
  19. Brady CB, Trevor KT, Stein TD, Deykin EY, Perkins SD, Averill JG, Guilderson L, McKee AC, Renner SW, Kowall NW. The Department of Veterans Affairs Biorepository Brain Bank: a national resource for amyotrophic lateral sclerosis research. Amyotroph Lateral Scler Frontotemporal Degener. 2013 Dec; 14(7-8):591-7. PMID: 23971854.
    View in: PubMed
  20. Stern RA, Daneshvar DH, Baugh CM, Seichepine DR, Montenigro PH, Riley DO, Fritts NG, Stamm JM, Robbins CA, McHale L, Simkin I, Stein TD, Alvarez VE, Goldstein LE, Budson AE, Kowall NW, Nowinski CJ, Cantu RC, McKee AC. Clinical presentation of chronic traumatic encephalopathy. Neurology. 2013 Sep 24; 81(13):1122-9. PMID: 23966253.
    View in: PubMed
  21. Perez-Nievas BG, Stein TD, Tai HC, Dols-Icardo O, Scotton TC, Barroeta-Espar I, Fernandez-Carballo L, de Munain EL, Perez J, Marquie M, Serrano-Pozo A, Frosch MP, Lowe V, Parisi JE, Petersen RC, Ikonomovic MD, López OL, Klunk W, Hyman BT, Gómez-Isla T. Dissecting phenotypic traits linked to human resilience to Alzheimer's pathology. Brain. 2013 Aug; 136(Pt 8):2510-26. PMID: 23824488.
    View in: PubMed
  22. McKee AC, Stern RA, Nowinski CJ, Stein TD, Alvarez VE, Daneshvar DH, Lee HS, Wojtowicz SM, Hall G, Baugh CM, Riley DO, Kubilus CA, Cormier KA, Jacobs MA, Martin BR, Abraham CR, Ikezu T, Reichard RR, Wolozin BL, Budson AE, Goldstein LE, Kowall NW, Cantu RC. The spectrum of disease in chronic traumatic encephalopathy. Brain. 2013 Jan; 136(Pt 1):43-64. PMID: 23208308.
    View in: PubMed
  23. Vucic S, Stein TD, Hedley-Whyte ET, Reddel SR, Tisch S, Kotschet K, Cros D, Kiernan MC. FOSMN syndrome: novel insight into disease pathophysiology. Neurology. 2012 Jul 3; 79(1):73-9. PMID: 22722633.
    View in: PubMed
  24. Goldstein LE, Fisher AM, Tagge CA, Zhang XL, Velisek L, Sullivan JA, Upreti C, Kracht JM, Ericsson M, Wojnarowicz MW, Goletiani CJ, Maglakelidze GM, Casey N, Moncaster JA, Minaeva O, Moir RD, Nowinski CJ, Stern RA, Cantu RC, Geiling J, Blusztajn JK, Wolozin BL, Ikezu T, Stein TD, Budson AE, Kowall NW, Chargin D, Sharon A, Saman S, Hall GF, Moss WC, Cleveland RO, Tanzi RE, Stanton PK, McKee AC. Chronic traumatic encephalopathy in blast-exposed military veterans and a blast neurotrauma mouse model. Sci Transl Med. 2012 May 16; 4(134):134ra60. PMID: 22593173.
    View in: PubMed
  25. Tritos NA, Schaefer PW, Stein TD. Case records of the Massachusetts General Hospital. Case 40-2011. A 52-year-old man with weakness, infections, and enlarged adrenal glands. N Engl J Med. 2011 Dec 29; 365(26):2520-30. PMID: 22204728.
    View in: PubMed
  26. Augustinack JC, Huber KE, Postelnicu GM, Kakunoori S, Wang R, van der Kouwe AJ, Wald LL, Stein TD, Frosch MP, Fischl B. Entorhinal verrucae geometry is coincident and correlates with Alzheimer's lesions: a combined neuropathology and high-resolution ex vivo MRI analysis. Acta Neuropathol. 2012 Jan; 123(1):85-96. PMID: 22160360.
    View in: PubMed
  27. Walcott BP, Nahed BV, Redjal N, Stein TD, Kahle KT, Coumans JV. Pathological mechanism of lumbar disc herniation resulting in neurogenic muscle hypertrophy. J Clin Neurosci. 2011 Dec; 18(12):1682-4. PMID: 21985744.
    View in: PubMed
  28. Jho DH, Spiliopoulos K, Stein TD, Williams Z. Concomitant presentation of a glioblastoma multiforme with superimposed abscess. World Neurosurg. 2011 Jan; 75(1):126-31; discussion 50-3. PMID: 21492676.
    View in: PubMed
  29. Nozari A, Dilekoz E, Sukhotinsky I, Stein T, Eikermann-Haerter K, Liu C, Wang Y, Frosch MP, Waeber C, Ayata C, Moskowitz MA. Microemboli may link spreading depression, migraine aura, and patent foramen ovale. Ann Neurol. 2010 Feb; 67(2):221-9. PMID: 20225282.
    View in: PubMed
  30. Souayah N, Cros D, Stein TD, Chong PS. Relapsing Guillain Barré Syndrome and nephrotic syndrome secondary to focal segmental glomerulosclerosis. J Neurol Sci. 2008 Jul 15; 270(1-2):184-8. PMID: 18325535.
    View in: PubMed
  31. Lee JM, Li J, Johnson DA, Stein TD, Kraft AD, Calkins MJ, Jakel RJ, Johnson JA. Nrf2, a multi-organ protector? FASEB J. 2005 Jul; 19(9):1061-6. PMID: 15985529.
    View in: PubMed
  32. Stein TD, Anders NJ, DeCarli C, Chan SL, Mattson MP, Johnson JA. Neutralization of transthyretin reverses the neuroprotective effects of secreted amyloid precursor protein (APP) in APPSW mice resulting in tau phosphorylation and loss of hippocampal neurons: support for the amyloid hypothesis. J Neurosci. 2004 Sep 1; 24(35):7707-17. PMID: 15342738.
    View in: PubMed
  33. Li J, Stein TD, Johnson JA. Genetic dissection of systemic autoimmune disease in Nrf2-deficient mice. Physiol Genomics. 2004 Aug 11; 18(3):261-72. PMID: 15173550.
    View in: PubMed
  34. Stein TD, Johnson JA. Genetic programming by the proteolytic fragments of the amyloid precursor protein: somewhere between confusion and clarity. Rev Neurosci. 2003; 14(4):317-41. PMID: 14640319.
    View in: PubMed
  35. Stein TD, Fedynyshyn JP, Kalil RE. Circulating autoantibodies recognize and bind dying neurons following injury to the brain. J Neuropathol Exp Neurol. 2002 Dec; 61(12):1100-8. PMID: 12484573.
    View in: PubMed
  36. Diffee GM, Seversen EA, Stein TD, Johnson JA. Microarray expression analysis of effects of exercise training: increase in atrial MLC-1 in rat ventricles. Am J Physiol Heart Circ Physiol. 2003 Mar; 284(3):H830-7. PMID: 12424097.
    View in: PubMed
  37. Stein TD, Johnson JA. Lack of neurodegeneration in transgenic mice overexpressing mutant amyloid precursor protein is associated with increased levels of transthyretin and the activation of cell survival pathways. J Neurosci. 2002 Sep 1; 22(17):7380-8. PMID: 12196559.
    View in: PubMed
  38. Stein TD, DeJesus OT. Effect of 6-fluoro-m-tyrosine on dopamine release and metabolism in rat striatum using in vivo microdialysis. Brain Res. 2000 Nov 24; 884(1--2):192-5. PMID: 11082501.
    View in: PubMed
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