Thor Stein, MD, PhD
Assistant Professor
Boston University School of Medicine
Dept of Pathology & Laboratory Medicine

MD, University of Wisconsin Madison
PhD, University of Wisconsin Madison



Dr. Stein completed his undergraduate and graduate studies at the University of Wisconsin- Madison where he earned his MD and PhD (neuroscience) degrees. He completed residency training in pathology and fellowship training in neuropathology at Massachusetts General Hospital. In 2011 he became Assistant Professor of Pathology at Boston University School of Medicine.

Research Interests:
Dr. Stein’s research interests involve the study of neurodegenerative diseases, including Alzheimer disease and Amyotrophic Lateral Sclerosis (ALS). He studies the role of trauma in the abnormal accumulation of tau and proteins involved in RNA processing. He is an acting neuropathologist involved with the brain banks for the Boston University Alzheimer Disease Center, CTE Center, Framingham Heart Study, as well as the National Veterans Administration ALS brain bank.

CTE Center Role:
Dr. Stein is part of the Neuropathology Core of the SLI-BU CTE Brain Bank, where he conducts neuropathological analysis of brain tissue and helps maintain the SLI-BU CTE Brain Bank.

Awards/Memberships:
Dr. Stein is a recipient of the 2011 American Association of Neuropathologists Moore Award. He is a member of the Society for Neuroscience and the College of American Pathologists.

VA Boston Healthcare System




Age-Associated Lipidomic Changes in Alzheimer's Disease
02/01/2019 - 11/30/2023 (Co-PI)
PI: Jan K. Blusztajn, PhD
NIH/National Institute on Aging
1R01AG057768-01A1

Epigenetic changes in synaptic and inflammatory genes involved in the age-dependent development of Alzheimer
09/15/2016 - 06/30/2021 (Multi-PI)
PI: Thor Stein, MD, PhD
NIH/National Institute on Aging
3RF1AG054156-01S1

Establishing a Biorepository of Amyotropic Lateral Sclerosis (ALS)
09/28/2015 - 09/27/2020 (PI)
McKing Consulting Corporation HHS/CDC/ATSDR


Establishing a Biorepository of Amyotropic Lateral Sclerosis (ALS)
09/28/2016 - 09/27/2019 (PI)
McKing Consulting Corporation HHS/CDC/ATSDR


Age-Associated Lipidomic Changes in Alzheimer's Disease
09/30/2017 - 01/31/2019 (Multi-PI)
PI: Thor Stein, MD, PhD
NIH/National Institute on Aging
1R56AG057768-01

Personnel Agreement for Research Services of Kerry Cormier
08/01/2015 - 07/31/2017 (PI)
Department of Veterans Administration, Bedford


ALS Brain Repository
06/01/2013 - 09/22/2016 (PI)
McKing Consulting Corporation HHS CDC





Yr Title Project-Sub Proj Pubs
2019 The neuropathology of mild traumatic brain injury in Alzheimer disease 2I01CX001038-05 4
2018 Epigenetic changes in synaptic and inflammatory genes involved in the age-dependent development of Alzheimer's disease pathologies and cognitive decline 3RF1AG054156-01S1 7
2018 The neuropathology of mild traumatic brain injury in Alzheimer's disease 5I01CX001038-04 4
2017 Age-Associated Lipidomic Changes in Alzheimer's Disease 1R56AG057768-01 4
2017 The neuropathology of mild traumatic brain injury in Alzheimer's disease 5I01CX001038-03 4
2016 Epigenetic changes in synaptic and inflammatory genes involved in the age-dependent development of Alzheimer's disease pathologies andcognitive decline 1RF1AG054156-01 7
2016 The neuropathology of mild traumatic brain injury in Alzheimer's disease 5I01CX001038-02 4
2016 VA Biorepository Brain Bank 5I01BX002466-03 4
2015 The neuropathology of mild traumatic brain injury in Alzheimer's disease 1I01CX001038-01A1 4
2015 VA Biorepository Brain Bank 5I01BX002466-02 4
Showing 10 of 11 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Armstrong RA, McKee AC, Stein TD, Alvarez VE, Cairns NJ. Cortical degeneration in chronic traumatic encephalopathy and Alzheimer's disease neuropathologic change. Neurol Sci. 2018 Dec 18.View Related Profiles. PMID: 30564964.
     
  2. Walt GS, Burris HM, Brady CB, Spencer KR, Alvarez VE, Huber BR, Guilderson L, Abdul Rauf N, Collins D, Singh T, Mathias R, Averill JG, Walker SE, Robey I, McKee AC, Kowall NW, Stein TD. Chronic Traumatic Encephalopathy Within an Amyotrophic Lateral Sclerosis Brain Bank Cohort. J Neuropathol Exp Neurol. 2018 Dec 01; 77(12):1091-1100.View Related Profiles. PMID: 30299493.
     
  3. Cherry JD, Mez J, Crary JF, Tripodis Y, Alvarez VE, Mahar I, Huber BR, Alosco ML, Nicks R, Abdolmohammadi B, Kiernan PT, Evers L, Svirsky S, Babcock K, Gardner HM, Meng G, Nowinski CJ, Martin BM, Dwyer B, Kowall NW, Cantu RC, Goldstein LE, Katz DI, Stern RA, Farrer LA, McKee AC, Stein TD. Variation in TMEM106B in chronic traumatic encephalopathy. Acta Neuropathol Commun. 2018 Nov 04; 6(1):115.View Related Profiles. PMID: 30390709.
     
  4. Morrison FG, Miller MW, Wolf EJ, Logue MW, Maniates H, Kwasnik D, Cherry JD, Svirsky S, Restaino A, Hildebrandt A, Aytan N, Stein TD, Alvarez VE, McKee AC, Huber BR. Reduced interleukin 1A gene expression in the dorsolateral prefrontal cortex of individuals with PTSD and depression. Neurosci Lett. 2019 Jan 23; 692:204-209.View Related Profiles. PMID: 30366016.
     
  5. Tao Q, Ang TFA, DeCarli C, Auerbach SH, Devine S, Stein TD, Zhang X, Massaro J, Au R, Qiu WQ. Association of Chronic Low-grade Inflammation With Risk of Alzheimer Disease in ApoE4 Carriers. JAMA Netw Open. 2018 Oct 05; 1(6):e183597.View Related Profiles. PMID: 30646251.
     
  6. Hsu ET, Gangolli M, Su S, Holleran L, Stein TD, Alvarez VE, McKee AC, Schmidt RE, Brody DL. Astrocytic degeneration in chronic traumatic encephalopathy. Acta Neuropathol. 2018 Dec; 136(6):955-972.View Related Profiles. PMID: 30194648.
     
  7. Adams JW, Alvarez VE, Mez J, Huber BR, Tripodis Y, Xia W, Meng G, Kubilus CA, Cormier K, Kiernan PT, Daneshvar DH, Chua AS, Svirsky S, Nicks R, Abdolmohammadi B, Evers L, Solomon TM, Cherry JD, Aytan N, Mahar I, Devine S, Auerbach S, Alosco ML, Nowinski CJ, Kowall NW, Goldstein LE, Dwyer B, Katz DI, Cantu RC, Stern RA, Au R, McKee AC, Stein TD. Lewy Body Pathology and Chronic Traumatic Encephalopathy Associated With Contact Sports. J Neuropathol Exp Neurol. 2018 Sep 01; 77(9):757-768.View Related Profiles. PMID: 30053297.
     
  8. Alosco ML, Tripodis Y, Fritts NG, Heslegrave A, Baugh CM, Conneely S, Mariani M, Martin BM, Frank S, Mez J, Stein TD, Cantu RC, McKee AC, Shaw LM, Trojanowski JQ, Blennow K, Zetterberg H, Stern RA. Cerebrospinal fluid tau, Aß, and sTREM2 in Former National Football League Players: Modeling the relationship between repetitive head impacts, microglial activation, and neurodegeneration. Alzheimers Dement. 2018 Sep; 14(9):1159-1170.View Related Profiles. PMID: 30049650.
     
  9. Alosco ML, Mez J, Tripodis Y, Kiernan PT, Abdolmohammadi B, Murphy L, Kowall NW, Stein TD, Huber BR, Goldstein LE, Cantu RC, Katz DI, Chaisson CE, Martin B, Solomon TM, McClean MD, Daneshvar DH, Nowinski CJ, Stern RA, McKee AC. Age of first exposure to tackle football and chronic traumatic encephalopathy. Ann Neurol. 2018 May; 83(5):886-901.View Related Profiles. PMID: 29710395.
     
  10. Chen M, Lee HK, Moo L, Hanlon E, Stein T, Xia W. Common proteomic profiles of induced pluripotent stem cell-derived three-dimensional neurons and brain tissue from Alzheimer patients. J Proteomics. 2018 Jun 30; 182:21-33.View Related Profiles. PMID: 29709615.
     
Showing 10 of 58 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 58 publications over 15 distinct years, with a maximum of 15 publications in 2018

YearPublications
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20031
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20051
20081
20101
20114
20123
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20143
20159
20166
20175
201815
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