Thor Stein, MD, PhD
Associate Professor
Boston University School of Medicine
Pathology & Laboratory Medicine

MD, University of Wisconsin Madison
PhD, University of Wisconsin Madison




Dr. Stein completed his undergraduate and graduate studies at the University of Wisconsin- Madison where he earned his MD and PhD (neuroscience) degrees. He completed residency training in pathology and fellowship training in neuropathology at Massachusetts General Hospital. In 2011 he became Assistant Professor of Pathology at Boston University School of Medicine.

Research Interests:
Dr. Stein’s research interests involve the study of neurodegenerative diseases, including Alzheimer disease and Amyotrophic Lateral Sclerosis (ALS). He studies the role of trauma in the abnormal accumulation of tau and proteins involved in RNA processing. He is an acting neuropathologist involved with the brain banks for the Boston University Alzheimer Disease Center, CTE Center, Framingham Heart Study, as well as the National Veterans Administration ALS brain bank.

CTE Center Role:
Dr. Stein is part of the Neuropathology Core of the SLI-BU CTE Brain Bank, where he conducts neuropathological analysis of brain tissue and helps maintain the SLI-BU CTE Brain Bank.

Awards/Memberships:
Dr. Stein is a recipient of the 2011 American Association of Neuropathologists Moore Award. He is a member of the Society for Neuroscience and the College of American Pathologists.

Investigator
Framingham Heart Study


VA Boston Healthcare System


Member
Boston University
Evans Center for Interdisciplinary Biomedical Research




Age-Associated Lipidomic Changes in Alzheimer's Disease
02/01/2019 - 01/31/2024 (Multi-PI)
PI: Thor Stein, MD, PhD
NIH/National Institute on Aging
1RF1AG057768-01A1

Epigenetic changes in synaptic and inflammatory genes involved in the age-dependent development of Alzheimer
09/15/2016 - 03/31/2021 (Multi-PI)
PI: Thor Stein, MD, PhD
NIH/National Institute on Aging
3RF1AG054156-01S1

Establishing a Biorepository of Amyotropic Lateral Sclerosis (ALS)
09/28/2016 - 09/27/2020 (Subcontract PI)
McKing Consulting Corporation HHS CDC ATSDR


Establishing a Biorepository of Amyotropic Lateral Sclerosis (ALS)
09/28/2015 - 09/27/2020 (Subcontract PI)
McKing Consulting Corporation HHS CDC ATSDR


Age-Associated Lipidomic Changes in Alzheimer's Disease
09/30/2017 - 01/31/2019 (Multi-PI)
PI: Thor Stein, MD, PhD
NIH/National Institute on Aging
1R56AG057768-01

Personnel Agreement for Research Services of Kerry Cormier
08/01/2015 - 07/31/2017 (PI)
Department of Veterans Administration, Bedford


ALS Brain Repository
06/01/2013 - 09/22/2016 (Subcontract PI)
McKing Consulting Corporation HHS CDC




Title
Epigenetic changes in synaptic and inflammatory genes involved in the age-dependent development of Alzheimer


Yr Title Project-Sub Proj Pubs
2020 The neuropathology of mild traumatic brain injury in Alzheimer disease 5I01CX001038-06 42
2019 Age-Associated Lipidomic Changes in Alzheimer's Disease 1RF1AG057768-01A1 4
2019 The neuropathology of mild traumatic brain injury in Alzheimer disease 2I01CX001038-05 42
2019 TBI-related polyproteinopathy and the role of multiple neurodegenerations in cognitive decline and parkinsonism 1U54NS115266-01-6602
2018 Epigenetic changes in synaptic and inflammatory genes involved in the age-dependent development of Alzheimer's disease pathologies and cognitive decline 3RF1AG054156-01S1 15
2018 The neuropathology of mild traumatic brain injury in Alzheimer's disease 5I01CX001038-04 42
2017 Age-Associated Lipidomic Changes in Alzheimer's Disease 1R56AG057768-01 7
2017 The neuropathology of mild traumatic brain injury in Alzheimer's disease 5I01CX001038-03 42
2017 VA Biorepository Brain Bank 5I01BX002466-04 8
2016 Epigenetic changes in synaptic and inflammatory genes involved in the age-dependent development of Alzheimer's disease pathologies andcognitive decline 1RF1AG054156-01 15
Showing 10 of 15 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Adams JW, Alosco ML, Mez J, Alvarez VE, Huber BR, Tripodis Y, Adler CH, Kubilius C, Cormier KA, Mathais R, Nicks R, Kelley HJ, Saltiel N, Uretsky M, Nair E, Aytan N, Cherry JD, Nowinski CJ, Kowall NW, Goldstein LE, Dwyer B, Katz DI, Cantu RC, Stern RA, McKee AC, Stein TD. Association of probable REM sleep behavior disorder with pathology and years of contact sports play in chronic traumatic encephalopathy. Acta Neuropathol. 2020 Sep 17.View Related Profiles. PMID: 32939646
     
  2. Subramanian ML, Vig V, Chung J, Fiorello MG, Xia W, Zetterberg H, Blennow K, Zetterberg M, Shareef F, Siegel NH, Ness S, Jun GR, Stein TD. Neurofilament light chain in the vitreous humor of the eye. Alzheimers Res Ther. 2020 Sep 17; 12(1):111.View Related Profiles. PMID: 32943089
     
  3. Warling A, Uchida R, Shin H, Dodelson C, Garcia ME, Shea-Shumsky NB, Svirsky S, Pothast M, Kelley H, Schumann CM, Brzezinski C, Bauman MD, Alexander A, McKee AC, Stein TD, Schall M, Jacobs B. Putative dendritic correlates of chronic traumatic encephalopathy: A preliminary quantitative Golgi exploration. J Comp Neurol. 2020 Sep 01.View Related Profiles. PMID: 32869318
     
  4. Alosco ML, Cherry JD, Huber BR, Tripodis Y, Baucom Z, Kowall NW, Saltiel N, Goldstein LE, Katz DI, Dwyer B, Daneshvar DH, Palmisano JN, Martin B, Cantu RC, Stern RA, Alvarez VE, Mez J, Stein TD, McKee AC. Characterizing tau deposition in chronic traumatic encephalopathy (CTE): utility of the McKee CTE staging scheme. Acta Neuropathol. 2020 Oct; 140(4):495-512.View Related Profiles. PMID: 32778942
     
  5. Mez J, Daneshvar DH, Alosco ML, Alvarez VE, Huber BR, Stein TD, McKee AC. Reply to "Chronic Traumatic Encephalopathy and Primary Age-Related Tauopathy". Ann Neurol. 2020 Aug 04.View Related Profiles. PMID: 32754941
     
  6. McKee AC, Stein TD, Crary JF, Bieniek KF, Cantu RC, Kovacs GG. Practical Considerations in the Diagnosis of Mild Chronic Traumatic Encephalopathy and Distinction From Age-Related Tau Astrogliopathy. J Neuropathol Exp Neurol. 2020 Aug 01; 79(8):921-924.View Related Profiles. PMID: 32688381
     
  7. Spencer KR, Foster ZW, Rauf NA, Guilderson L, Collins D, Averill JG, Walker SE, Robey I, Cherry JD, Alvarez VE, Huber BR, McKee AC, Kowall NW, Brady CB, Stein TD. Neuropathological profile of long-duration amyotrophic lateral sclerosis in military Veterans. Brain Pathol. 2020 Jul 07.View Related Profiles. PMID: 32633852
     
  8. Cherry JD, Kim SH, Stein TD, Pothast MJ, Nicks R, Meng G, Huber BR, Mez J, Alosco ML, Tripodis Y, Farrell K, Alvarez VE, McKee AC, Crary JF. Evolution of neuronal and glial tau isoforms in chronic traumatic encephalopathy. Brain Pathol. 2020 Sep; 30(5):913-925.View Related Profiles. PMID: 32500646; DOI: 10.1111/bpa.12867;
     
  9. Stein TD, Crary JF. Chronic Traumatic Encephalopathy and Neuropathological Comorbidities. Semin Neurol. 2020 Aug; 40(4):384-393. PMID: 32629520
     
  10. Alosco ML, Tripodis Y, Baucom ZH, Mez J, Stein TD, Martin B, Haller O, Conneely S, McClean M, Nosheny R, Mackin S, McKee AC, Weiner MW, Stern RA. Late contributions of repetitive head impacts and TBI to depression symptoms and cognition. Neurology. 2020 Aug 18; 95(7):e793-e804.View Related Profiles. PMID: 32591472; DOI: 10.1212/WNL.0000000000010040;
     
Showing 10 of 81 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 81 publications over 17 distinct years, with a maximum of 15 publications in 2018

YearPublications
20001
20023
20031
20042
20051
20081
20101
20114
20123
20133
20143
20159
20166
20175
201815
20199
202014


Recent (within 3 months)

Boston University research shows rare sleep disorder impacts contact sport athletes

WCVB-TV 9/17/2020

CTE, Contact Sports Play Linked to REM Sleep Behavior Disorder

BU Today 9/16/2020
Older

Boston University researchers discover link between CTE and severe sleep disorder

WHDH-TV 9/16/2019

Tau Pathology Present Decades After a Single Brain Injury

The Scientist 9/9/2019

Study: Playing Contact Sports Significantly Increases Risk Of Lewy Body Disease, Parkinson’s

StudyFinds 4/15/2019

Why Some People Develop More Severe CTE Symptoms than Others

Association of American Universities 11/21/2018

Scientists zero in on genetic risk factor for Alzheimer's-like brain disease CTE

WBUR 11/5/2018

Specific Gene Variant Linked To Severe Symptoms Of CTE

UPI 11/5/2018

BU researchers make first link from severe CTE to genes

The Boston Globe 11/4/2018

Why Some People’s CTE Symptoms Are More Severe Than Others

BU Today 11/3/2018

Parkinson’s Symptoms Associated with Contact Sports

Genetic Engineering & Biotechnology News 7/26/2018
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