Ryan Ferguson, PhD
Clinical Assistant Professor
Boston University School of Public Health
Dept of Epidemiology

MPH, Boston University School of Public Health
DSc, Boston University School of Public Health
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Ryan Ferguson is Director of the Cooperative Studies Program Coordinating Center within the U.S. Department of Veterans Affairs. He is responsible for the planning, execution and analysis of large scale clinical trials within a 140 person research enterprise funded by the Department of Veterans Affairs. The Center (the Massachusetts Veterans Epidemiology Research and Information Center) provides the Department with expertise in large scale clinical trials, epidemiological studies, biobanking and biomedical informatics. Among his current portfolio is the Point of Care Research Program. This national project uses innovative health informatics to embed clinical research in the clinical care system in order to create a 'learning healthcare system'.

The majority of clinical trials conducted by the program are Phase III-IV IND/IDE regulated trials. The Center develops investigator-initiated research letters of intent into full proposals. The process involves a series of planning meetings with national and international content experts and culminates with a mature protocol including study design, data collection forms, statistical analysis plans and monitoring procedures. Protocols are then defended through a peer-reviewed process. After approval, the Center executes the trials using recruitment sites at clinical centers across the country (VA and non-VA) . International collaborations with Canada and Australia are currently being executed. The studies range from hundreds to thousands of participants at up to 40 recruitment sites and run from 2 - 7 years in duration. The clinical trials have been developed in many content areas including pulmonary disease, rheumatoid arthritis, schizophrenia, alcoholism, diabetes, cardiovascular disease, post-traumatic stress disorder and oncology. The Center has published clinical trial results in prestigious medical journals and has presented results at national and international medical conferences.

During his tenure as the Center Director the Center became ISO 9001 registered as a clinical trial coordinating center, and risk-based monitoring and other innovative operational changes were implemented. In addition to his center leadership duties, Dr. Ferguson is a co-Principal Investigator for the VA Point of Care Program, a pragmatic trial program that embeds clinical operations into the VA EMR. He is also the Principal Investigator responsible independent epidemiologic research in chronic diseases in the veteran population.


Personnel Agreement for Research Services of Ryan Ferguson
01/01/2013 - 09/30/2014 (PI)
Boston VA Research Institute, Inc. Allergan Sales Inc




Yr Title Project-Sub Proj Pubs
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Huang H, Turner M, Raju S, Reich J, Leatherman S, Armstrong K, Woods P, Ferguson RE, Fiore LD, Lederle FA. Identification of Acute Decompensated Heart Failure Hospitalizations Using Administrative Data. Am J Cardiol. 2017 Jun 01; 119(11):1791-1796.View Related Profiles. PMID: 28395889; DOI: 10.1016/j.amjcard.2017.03.007;.
  2. Gradus JL, Leatherman S, Curreri A, Myers LG, Ferguson R, Miller M. Gender differences in substance abuse, PTSD and intentional self-harm among veterans health administration patients. Drug Alcohol Depend. 2017 Feb 01; 171:66-69.View Related Profiles. PMID: 28013099; DOI: 10.1016/j.drugalcdep.2016.11.012;.
  3. Lederle FA, Cushman WC, Ferguson RE, Brophy MT, Fiore Md LD. Chlorthalidone Versus Hydrochlorothiazide: A New Kind of Veterans Affairs Cooperative Study. Ann Intern Med. 2016 Nov 01; 165(9):663-664.View Related Profiles. PMID: 27538129; DOI: 10.7326/M16-1208;.
  4. Fiore LD, Brophy MT, Turek S, Kudesia V, Ramnath N, Shannon C, Ferguson R, Pyarajan S, Fiore MA, Hornberger J, Lavori P. The VA Point-of-Care Precision Oncology Program: Balancing Access with Rapid Learning in Molecular Cancer Medicine. Biomark Cancer. 2016; 8:9-16.View Related Profiles. PMID: 26949343; DOI: 10.4137/BIC.S37548;.
  5. D'Avolio L, Ferguson R, Goryachev S, Woods P, Sabin T, O'Neil J, Conrad C, Gillon J, Escalera J, Brophy M, Lavori P, Fiore L. Implementation of the Department of Veterans Affairs' first point-of-care clinical trial. J Am Med Inform Assoc. 2012 Jun; 19(e1):e170-6.View Related Profiles. PMID: 22366293; PMCID: PMC3392864.
  6. Fiore LD, Brophy M, Ferguson RE, D'Avolio L, Hermos JA, Lew RA, Doros G, Conrad CH, O'Neil JA, Sabin TP, Kaufman J, Swartz SL, Lawler E, Liang MH, Gaziano JM, Lavori PW. A point-of-care clinical trial comparing insulin administered using a sliding scale versus a weight-based regimen. Clin Trials. 2011 Apr; 8(2):183-95.View Related Profiles. PMID: 21478329; PMCID: PMC3195898; DOI: 10.1177/1740774510395635;.
  7. Huang GD, Ferguson RE, Peduzzi PN, O''Leary TJ. Scientific and organizational collaboration in comparative effectiveness research: the VA cooperative studies program model. Am J Med. 2010 Dec; 123(12 Suppl 1):e24-31. PMID: 21184863; DOI: 10.1016/j.amjmed.2010.10.005;.

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 7 publications over 5 distinct years, with a maximum of 3 publications in 2016

YearPublications
20101
20111
20121
20163
20171
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715 Albany St Talbot Building
Boston MA 02118
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