Gheorghe Doros, PhD
Professor
Boston University School of Public Health
Biostatistics

PhD, Yale University
MA, Yale University
MS, University of Bucharest
BS, University of Bucharest



Gheorghe Doros is Professor of Biostatistics and director of the Biostatistics Consulting Group. He received his PhD in Statistics from Yale University and joined BUSPH’s Department of Biostatistics in 2006 after spending two years at Eli Lilly, as a member of that company's Drug Discovery and Toxicology department. Dr. Doros’s research on methodological approaches and strategies has been concentrated in the area of clinical trials, more specifically on Bayesian approaches to clinical trials and the area of placebo response in clinical trials. The outcome of his work has been a corner stone in developing a host of collaborations with outstanding faculty, clinicians, and researchers at the Boston University Medical Campus and at other institutions. These productive collaborations have resulted in several federally funded grants. Dr. Doros authored and co-authored many peer-reviewed publications of original and innovative research which has had a major impact on the field. On the majority of publications, Dr. Doros is the lead statistician author. He demonstrated continuing record of multidisciplinary research that has had a major impact on the rapidly changing field. His publications on clinical trials; most proposing the design, analysis and new methodologies or of significant contributions to this field.

Dr. Doros is a very active and effective teacher and mentor in the department of Biostatistics. His teaching philosophy is to pursue an active approach to learning and to engage students to think critically. He taught core and elective courses for Master and PhD-level courses. The excellent course evaluations he received attests to his ability in engaging students in active learning. Dr. Doros has been awarded the excellence in teaching three times in three years.

On a national level, Dr. Doros has served as an Associate Editor for the BioMed Central’s journal Trials and as a reviewer for a number of academic journals. He served as a member of the merit review subcommittee for Epidemiology of the Department of Veteran Affairs and a member NHLBI-Ancillary Studies in Clinical Trials between 2012 and 2014. He has served as a statistical expert on a number of Independent Data Monitoring Committee(IDMC) for clinical trials and clinical programs. He served or seves as a senior consultant on multicenter trials and/or programs for the following organizations Pfizer, Takeda, Avanir, Sarepta and Children's Hospital.

Member
Boston University
BU-BMC Cancer Center


Boston Medical Center




Biostatisics VA Support - Doros Group
08/26/2021 - 08/25/2026 (PI)
Department of Veterans Administration


Mechanistic underpinnings of increased adipose tissue in HFpEF
07/01/2019 - 06/30/2024 (Key Person)
PI: Flora Sam, MD
NIH/National Heart, Lung, and Blood Institute
5R01HL145985-04

Gheorghe Doros, PhD: Statistical research in clinical trials (Baim Institute for Clinical Research)
09/01/2017 - 08/31/2023 (PI)
Baim Institute for Clinical Research


VA241-16-D-0012 VA Master Contract Task Order 24
09/01/2020 - 08/31/2021 (PI)
VA Boston Healthcare System


VA241-16-D-0012 VA Master Contract Task Order 19 (Luke Zheng)
05/01/2020 - 08/31/2021 (PI)
VA Boston Healthcare System


VA241-16-D-0012 VA Master Contract Task Order 18
09/01/2019 - 08/31/2020 (PI)
VA Boston Healthcare System


Personnel Agreement for Research Services of Gheorghe Doros
05/01/2016 - 08/31/2019 (PI)
VA Boston Healthcare System


Role of Aldosterone and Adiponectin in Inter-Tissue Communication in Diastolic Heart Failure
06/01/2016 - 05/31/2019 (Key Person)
PI: Flora Sam, MD
NIH/National Heart, Lung, and Blood Institute
4R01HL117153-04

Gheorghe Doros, PhD (faculty): Statistical research in clinical trials (Harvard Clinical Research Institute)
09/01/2016 - 08/31/2017 (PI)
Harvard Clinical Research Institute


Role of Aldosterone and Adiponectin in Inter-Tissue Communication in Diastolic Heart Failure
09/01/2013 - 05/31/2016 (Key Person)
PI: Flora Sam, MD
NIH/National Heart, Lung, and Blood Institute
5R01HL117153-03

Showing 10 of 15 results. Show All Results


Title


Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Conte MS, Azene E, Doros G, Gasper WJ, Hamza T, Kashyap VS, Guzman R, Mena-Hurtado C, Menard MT, Rosenfield K, Rowe VL, Strong M, Farber A. Secondary interventions following open vs endovascular revascularization for chronic limb threatening ischemia in the BEST-CLI trial. J Vasc Surg. 2024 Feb 17.View Related Profiles. PMID: 38368997
     
  2. Misfeld M, Sandner S, Caliskan E, Böning A, Aramendi J, Salzberg SP, Choi YH, Perrault LP, Tekin I, Cuerpo GP, Lopez-Menendez J, Weltert LP, Adsuar-Gomez A, Thielmann M, Serraino GF, Doros G, Borger MA, Emmert MY. Outcomes after surgical revascularization in diabetic patients. Interdiscip Cardiovasc Thorac Surg. 2024 Feb 02; 38(2). PMID: 38218725; PMCID: PMC10850843; DOI: 10.1093/icvts/ivae014;
     
  3. Lau KHV, Prokaeva T, Zheng L, Doros G, Kaku MC, Spencer B, Berk J, Sanchorawala V. Neurofilament light chain kinetics as a biomarker for polyneuropathy in V122I hereditary transthyretin amyloidosis. Amyloid. 2023 Dec 11; 1-3.View Related Profiles. PMID: 38073425
     
  4. Farber A, Siracuse JJ, Giles K, Jones DW, Laskowski IA, Powell RJ, Rosenfield K, Strong MB, White CJ, Doros G, Menard MT. Investigator attitudes on equipoise and practice patterns in the BEST-CLI trial. J Vasc Surg. 2024 Apr; 79(4):865-874.View Related Profiles. PMID: 38056700
     
  5. Sarosiek S, Lee MH, Doros G, Edwards CV, Quillen K, Brauneis D, Shelton AC, Sanchorawala V, Sloan JM. Safety and Efficacy of Propylene Glycol-Free Melphalan in Patients with AL Amyloidosis Undergoing Autologous Stem Cell Transplantation: Results of a Phase II Study. Transplant Cell Ther. 2023 Nov; 29(11):695.e1-695.e7.View Related Profiles. PMID: 37607644
     
  6. Buckler AJ, Doros G, Kinninger A, Lakshmanan S, Le VT, Libby P, May HT, Muhlestein JB, Nelson JR, Nicolaou A, Roy SK, Shaikh K, Shekar C, Tayek JA, Zheng L, Bhatt DL, Budoff MJ. Quantitative imaging biomarkers of coronary plaque morphology: insights from EVAPORATE. Front Cardiovasc Med. 2023; 10:1204071. PMID: 37600044; PMCID: PMC10435977; DOI: 10.3389/fcvm.2023.1204071;
     
  7. Rabbat MG, Lakshmanan S, Benjamin MM, Doros G, Kinninger A, Budoff MJ, Bhatt DL. Benefit of icosapent ethyl on coronary physiology assessed by computed tomography angiography fractional flow reserve: EVAPORATE-FFRCT. Eur Heart J Cardiovasc Imaging. 2023 Jun 21; 24(7):866-873. PMID: 37082990; PMCID: PMC10284047; DOI: 10.1093/ehjci/jead063;
     
  8. Siracuse JJ, Farber A, Menard MT, Conte MS, Kaufman JA, Jaff M, Kiang SC, Ochoa Chaar CI, Osborne N, Singh N, Tan TW, Guzman RJ, Strong MB, Hamza TH, Doros G, Rosenfield K. Perioperative complications following open or endovascular revascularization for chronic limb-threatening ischemia in the BEST-CLI Trial. J Vasc Surg. 2023 Oct; 78(4):1012-1020.e2.View Related Profiles. PMID: 37318428
     
  9. Cannon CP, Kim JM, Lee JJ, Sutherland J, Bachireddy R, Valentine CM, Hearne S, Trebnick A, Jaffer S, Datta S, Semmel E, Thorpe F, Doros G, Cavender MA, Reynolds MR. Patients and Their Physician's Perspectives About Oral Anticoagulation in Patients With Atrial Fibrillation Not Receiving an Anticoagulant. JAMA Netw Open. 2023 Apr 03; 6(4):e239638. PMID: 37093601; PMCID: PMC10126870; DOI: 10.1001/jamanetworkopen.2023.9638;
     
  10. Sandner S, Misfeld M, Caliskan E, Böning A, Aramendi J, Salzberg SP, Choi YH, Perrault LP, Tekin I, Cuerpo GP, Lopez-Menendez J, Weltert LP, Böhm J, Krane M, González-Santos JM, Tellez JC, Holubec T, Ferrari E, Doros G, Vitarello CJ, Emmert MY. Clinical outcomes and quality of life after contemporary isolated coronary bypass grafting: a prospective cohort study. Int J Surg. 2023 Apr 01; 109(4):707-715. PMID: 36912566; PMCID: PMC10389413; DOI: 10.1097/JS9.0000000000000259;
     
Showing 10 of 344 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 344 publications over 22 distinct years, with a maximum of 41 publications in 2014

YearPublications
20031
20041
20051
20063
20077
20084
200914
201014
201115
20129
201321
201441
201539
201628
201739
201836
201922
202010
202114
202214
20239
20242


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2008-2010 Boston University School of Public Health: Excellence in Teaching Award
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