Hanni Menn-Josephy, MD
|Institution||Boston University School of Medicine|
|Address||650 Albany St Evans Biomed Research Ctr|
I am an attending physician in the nephrology section at Boston Medical Center, with a special interest in autoimmune kidney diseases in general and lupus nephritis in particular. As a nephrology fellow at Boston University, I worked under the mentorship of Dr. Ian Rifkin and studied IFN regulating pathways in both lupus mice models, as well as in primary human cells.
Since 2011, in collaboration with Drs. Ramon Bonegio (nephrology), Ian Rifkin (nephrology), Michael York (rheumatology), and Christina Lam (dermatology), I helped establish a multidisciplinary lupus and autoimmunity clinic at the Boston Medical Center, where I currently work and treat patients with lupus nephritis. Since we established the Lupus Program, our center participated in four clinical trials involving lupus patients who are refractory to standard therapies. In 2013 we established an autoimmunity registry of patients and sample repository and we have collected and stored renal biopsy samples, samples for genetic testing, serum and peripheral blood mononuclear cells from patients with lupus nephritis both at times of high disease activity and during remission.
As a physician- scientist my research focus is to conduct translational studies utilizing tissue samples from my clinic patients, with the goal of better understanding of the inflammatory pathways that are responsible for the pathogenesis of lupus and lupus nephritis.
I have a strong commitment to try and identify better therapeutic targets for my patients with lupus and lupus nephritis, since current treatments are non specific, have significant toxicity, and most of the patients do not achieve a complete remission.
- Lupus nephritis
- Mechanisms of autoimmunity
- Mechanisms of autoimmune kidney disease
- Avoiding toxicity of immunosuppression
Click the "See All" links for more information and interactive visualizations!
Similar BU People
BU People who are also in this person's primary department.