Keywords
Last Name

Susan Fried, PhD

TitleAdjunct Professor
InstitutionBoston University School of Medicine
DepartmentMedicine
DivisionEndocrinology, Diabetes & Nutrition
Address650 Albany St Evans Biomed Research Ctr
Boston MA 02118
Phone(617) 638-7110
ORCID ORCID Icon0000-0003-1101-9332
Other Positions
TitleDirector, Boston Nutrition and Obesity Research Center (BNORC)
InstitutionBoston University School of Medicine

TitleDirector, Adipose Biology and Nutrient Metabolism Core, BNORC
InstitutionBoston University School of Medicine

TitleDirector, Affinity Research Collaborative on “Sex differences in Adipose Tissue and Obesity-related Metabolic Diseases”
InstitutionBoston University School of Medicine

TitleGraduate Faculty (Primary Mentor of Grad Students)
InstitutionBoston University School of Medicine, Division of Graduate Medical Sciences

InstitutionBoston Medical Center

 Research Expertise & Professional Interests
Expertise includes: Obesity; Adipocyte biology; Nutrition.

 Self-Described Keywords
  • ADIPOSE TISSUE
  • OBESITY
 Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Pickering RT, Lee MJ, Karastergiou K, Gower A, Fried SK. Depot Dependent Effects of Dexamethasone on Gene Expression in Human Omental and Abdominal Subcutaneous Adipose Tissues from Obese Women. PLoS One. 2016; 11(12):e0167337. PMID: 28005982.
    View in: PubMed
  2. Fried SK. Adipocyte size redux. Obesity (Silver Spring). 2017 Jan; 25(1):15. PMID: 27935267.
    View in: PubMed
  3. Wu Y, Lee MJ, Ido Y, Fried SK. High-fat diet-induced obesity regulates MMP3 to modulate depot- and sex-dependent adipose expansion in C57BL/6J mice. Am J Physiol Endocrinol Metab. 2017 Jan 01; 312(1):E58-E71. PMID: 27879248.
    View in: PubMed
  4. Lee MJ, Yang RZ, Karastergiou K, Smith SR, Chang JR, Gong DW, Fried SK. Low expression of the GILZ may contribute to adipose inflammation and altered adipokine production in human obesity. J Lipid Res. 2016 Jul; 57(7):1256-63. PMID: 27178044.
    View in: PubMed
  5. Karastergiou K, Bredella MA, Lee MJ, Smith SR, Fried SK, Miller KK. Growth hormone receptor expression in human gluteal versus abdominal subcutaneous adipose tissue: Association with body shape. Obesity (Silver Spring). 2016 May; 24(5):1090-6. PMID: 27015877.
    View in: PubMed
  6. Lillis AP, Muratoglu SC, Au DT, Migliorini M, Lee MJ, Fried SK, Mikhailenko I, Strickland DK. Correction: LDL Receptor-Related Protein-1 (LRP1) Regulates Cholesterol Accumulation in Macrophages. PLoS One. 2016; 11(1):e0147457. PMID: 26797092.
    View in: PubMed
  7. Jedrychowski MP, Liu L, Laflamme CJ, Karastergiou K, Meshulam T, Ding SY, Wu Y, Lee MJ, Gygi SP, Fried SK, Pilch PF. Adiporedoxin, an upstream regulator of ER oxidative folding and protein secretion in adipocytes. Mol Metab. 2015 Nov; 4(11):758-70. PMID: 26629401.
    View in: PubMed
  8. Jang H, Bhasin S, Guarneri T, Serra C, Schneider M, Lee MJ, Guo W, Fried SK, Pencina K, Jasuja R. The Effects of a Single Developmentally Entrained Pulse of Testosterone in Female Neonatal Mice on Reproductive and Metabolic Functions in Adult Life. Endocrinology. 2015 Oct; 156(10):3737-46. PMID: 26132920.
    View in: PubMed
  9. Lillis AP, Muratoglu SC, Au DT, Migliorini M, Lee MJ, Fried SK, Mikhailenko I, Strickland DK. LDL Receptor-Related Protein-1 (LRP1) Regulates Cholesterol Accumulation in Macrophages. PLoS One. 2015; 10(6):e0128903. PMID: 26061292.
    View in: PubMed
  10. Fried SK, Lee MJ, Karastergiou K. Shaping fat distribution: New insights into the molecular determinants of depot- and sex-dependent adipose biology. Obesity (Silver Spring). 2015 Jul; 23(7):1345-52. PMID: 26054752.
    View in: PubMed
  11. Watkins AA, Yasuda K, Wilson GE, Aprahamian T, Xie Y, Maganto-Garcia E, Shukla P, Oberlander L, Laskow B, Menn-Josephy H, Wu Y, Duffau P, Fried SK, Lichtman AH, Bonegio RG, Rifkin IR. IRF5 deficiency ameliorates lupus but promotes atherosclerosis and metabolic dysfunction in a mouse model of lupus-associated atherosclerosis. J Immunol. 2015 Feb 15; 194(4):1467-79. PMID: 25595782.
    View in: PubMed
  12. Divoux A, Karastergiou K, Xie H, Guo W, Perera RJ, Fried SK, Smith SR. Identification of a novel lncRNA in gluteal adipose tissue and evidence for its positive effect on preadipocyte differentiation. Obesity (Silver Spring). 2014 Aug; 22(8):1781-5. PMID: 24862299.
    View in: PubMed
  13. Lee MJ, Fried SK. Reply to Armani et al. Can cortisol stimulate adipogenesis without the glucocorticoid receptor? Int J Obes (Lond). 2014 Dec; 38(12):1578-9. PMID: 24785104.
    View in: PubMed
  14. Ding SY, Lee MJ, Summer R, Liu L, Fried SK, Pilch PF. Pleiotropic effects of cavin-1 deficiency on lipid metabolism. J Biol Chem. 2014 Mar 21; 289(12):8473-83. PMID: 24509860.
    View in: PubMed
  15. Lee MJ, Fried SK. The glucocorticoid receptor, not the mineralocorticoid receptor, plays the dominant role in adipogenesis and adipokine production in human adipocytes. Int J Obes (Lond). 2014 Sep; 38(9):1228-33. PMID: 24430397.
    View in: PubMed
  16. Lee MJ, Fried SK. Optimal protocol for the differentiation and metabolic analysis of human adipose stromal cells. Methods Enzymol. 2014; 538:49-65. PMID: 24529433.
    View in: PubMed
  17. Karastergiou K, Fried SK. Multiple adipose depots increase cardiovascular risk via local and systemic effects. Curr Atheroscler Rep. 2013 Oct; 15(10):361. PMID: 23982264.
    View in: PubMed
  18. Gajda AM, Zhou YX, Agellon LB, Fried SK, Kodukula S, Fortson W, Patel K, Storch J. Direct comparison of mice null for liver or intestinal fatty acid-binding proteins reveals highly divergent phenotypic responses to high fat feeding. J Biol Chem. 2013 Oct 18; 288(42):30330-44. PMID: 23990461.
    View in: PubMed
  19. Chakrabarti P, Kim JY, Singh M, Shin YK, Kim J, Kumbrink J, Wu Y, Lee MJ, Kirsch KH, Fried SK, Kandror KV. Insulin inhibits lipolysis in adipocytes via the evolutionarily conserved mTORC1-Egr1-ATGL-mediated pathway. Mol Cell Biol. 2013 Sep; 33(18):3659-66. PMID: 23858058.
    View in: PubMed
  20. Lee MJ, Pramyothin P, Karastergiou K, Fried SK. Deconstructing the roles of glucocorticoids in adipose tissue biology and the development of central obesity. Biochim Biophys Acta. 2014 Mar; 1842(3):473-81. PMID: 23735216.
    View in: PubMed
  21. Grahn TH, Zhang Y, Lee MJ, Sommer AG, Mostoslavsky G, Fried SK, Greenberg AS, Puri V. FSP27 and PLIN1 interaction promotes the formation of large lipid droplets in human adipocytes. Biochem Biophys Res Commun. 2013 Mar 8; 432(2):296-301. PMID: 23399566.
    View in: PubMed
  22. Nimitphong H, Holick MF, Fried SK, Lee MJ. 25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 promote the differentiation of human subcutaneous preadipocytes. PLoS One. 2012; 7(12):e52171. PMID: 23272223.
    View in: PubMed
  23. Karastergiou K, Fried SK, Xie H, Lee MJ, Divoux A, Rosencrantz MA, Chang RJ, Smith SR. Distinct developmental signatures of human abdominal and gluteal subcutaneous adipose tissue depots. J Clin Endocrinol Metab. 2013 Jan; 98(1):362-71. PMID: 23150689.
    View in: PubMed
  24. Lee MJ, Wu Y, Fried SK. Adipose tissue heterogeneity: implication of depot differences in adipose tissue for obesity complications. Mol Aspects Med. 2013 Feb; 34(1):1-11. PMID: 23068073.
    View in: PubMed
  25. Lee MJ, Fried SK. Glucocorticoids antagonize tumor necrosis factor-a-stimulated lipolysis and resistance to the antilipolytic effect of insulin in human adipocytes. Am J Physiol Endocrinol Metab. 2012 Nov 1; 303(9):E1126-33. PMID: 22949029.
    View in: PubMed
  26. Karastergiou K, Smith SR, Greenberg AS, Fried SK. Sex differences in human adipose tissues - the biology of pear shape. Biol Sex Differ. 2012; 3(1):13. PMID: 22651247.
    View in: PubMed
  27. Lee MJ, Wu Y, Fried SK. A modified protocol to maximize differentiation of human preadipocytes and improve metabolic phenotypes. Obesity (Silver Spring). 2012 Dec; 20(12):2334-40. PMID: 22627913.
    View in: PubMed
  28. Fried SK, Greenberg AS. Lipocalin 2: a "sexy" adipokine that regulates 17ß-estradiol and obesity. Endocrinology. 2012 Apr; 153(4):1582-4. PMID: 22408176.
    View in: PubMed
  29. Carswell KA, Lee MJ, Fried SK. Culture of isolated human adipocytes and isolated adipose tissue. Methods Mol Biol. 2012; 806:203-14. PMID: 22057454.
    View in: PubMed
  30. Lee MJ, Gong DW, Burkey BF, Fried SK. Pathways regulated by glucocorticoids in omental and subcutaneous human adipose tissues: a microarray study. Am J Physiol Endocrinol Metab. 2011 Mar; 300(3):E571-80. PMID: 21189358.
    View in: PubMed
  31. Lee EK, Lee MJ, Abdelmohsen K, Kim W, Kim MM, Srikantan S, Martindale JL, Hutchison ER, Kim HH, Marasa BS, Selimyan R, Egan JM, Smith SR, Fried SK, Gorospe M. miR-130 suppresses adipogenesis by inhibiting peroxisome proliferator-activated receptor gamma expression. Mol Cell Biol. 2011 Feb; 31(4):626-38. PMID: 21135128.
    View in: PubMed
  32. Lee MJ, Wu Y, Fried SK. Adipose tissue remodeling in pathophysiology of obesity. Curr Opin Clin Nutr Metab Care. 2010 Jul; 13(4):371-6. PMID: 20531178.
    View in: PubMed
  33. Grove KL, Fried SK, Greenberg AS, Xiao XQ, Clegg DJ. A microarray analysis of sexual dimorphism of adipose tissues in high-fat-diet-induced obese mice. Int J Obes (Lond). 2010 Jun; 34(6):989-1000. PMID: 20157318.
    View in: PubMed
  34. Fried SK, Tittelbach T, Blumenthal J, Sreenivasan U, Robey L, Yi J, Khan S, Hollender C, Ryan AS, Goldberg AP. Resistance to the antilipolytic effect of insulin in adipocytes of African-American compared to Caucasian postmenopausal women. J Lipid Res. 2010 May; 51(5):1193-200. PMID: 19965580.
    View in: PubMed
  35. Lee MJ, Fried SK. Integration of hormonal and nutrient signals that regulate leptin synthesis and secretion. Am J Physiol Endocrinol Metab. 2009 Jun; 296(6):E1230-8. PMID: 19318513.
    View in: PubMed
  36. Jobgen W, Meininger CJ, Jobgen SC, Li P, Lee MJ, Smith SB, Spencer TE, Fried SK, Wu G. Dietary L-arginine supplementation reduces white fat gain and enhances skeletal muscle and brown fat masses in diet-induced obese rats. J Nutr. 2009 Feb; 139(2):230-7. PMID: 19106310.
    View in: PubMed
  37. Bell M, Wang H, Chen H, McLenithan JC, Gong DW, Yang RZ, Yu D, Fried SK, Quon MJ, Londos C, Sztalryd C. Consequences of lipid droplet coat protein downregulation in liver cells: abnormal lipid droplet metabolism and induction of insulin resistance. Diabetes. 2008 Aug; 57(8):2037-45. PMID: 18487449.
    View in: PubMed
  38. Lee MJ, Fried SK, Mundt SS, Wang Y, Sullivan S, Stefanni A, Daugherty BL, Hermanowski-Vosatka A. Depot-specific regulation of the conversion of cortisone to cortisol in human adipose tissue. Obesity (Silver Spring). 2008 Jun; 16(6):1178-85. PMID: 18388900.
    View in: PubMed
  39. Berk ES, Johnson JA, Lee M, Zhang K, Boozer CN, Pi-Sunyer FX, Fried SK, Albu JB. Higher post-absorptive skeletal muscle LPL activity in African American vs. non-Hispanic White pre-menopausal women. Obesity (Silver Spring). 2008 Jan; 16(1):199-201. PMID: 18223635.
    View in: PubMed
  40. Varma V, Yao-Borengasser A, Bodles AM, Rasouli N, Phanavanh B, Nolen GT, Kern EM, Nagarajan R, Spencer HJ, Lee MJ, Fried SK, McGehee RE, Peterson CA, Kern PA. Thrombospondin-1 is an adipokine associated with obesity, adipose inflammation, and insulin resistance. Diabetes. 2008 Feb; 57(2):432-9. PMID: 18057090.
    View in: PubMed
  41. Fried SK, Watford M. Leucing weight with a futile cycle. Cell Metab. 2007 Sep; 6(3):155-6. PMID: 17767901.
    View in: PubMed
  42. Yao-Borengasser A, Varma V, Bodles AM, Rasouli N, Phanavanh B, Lee MJ, Starks T, Kern LM, Spencer HJ, Rashidi AA, McGehee RE, Fried SK, Kern PA. Retinol binding protein 4 expression in humans: relationship to insulin resistance, inflammation, and response to pioglitazone. J Clin Endocrinol Metab. 2007 Jul; 92(7):2590-7. PMID: 17595259.
    View in: PubMed
  43. de Souza Batista CM, Yang RZ, Lee MJ, Glynn NM, Yu DZ, Pray J, Ndubuizu K, Patil S, Schwartz A, Kligman M, Fried SK, Gong DW, Shuldiner AR, Pollin TI, McLenithan JC. Omentin plasma levels and gene expression are decreased in obesity. Diabetes. 2007 Jun; 56(6):1655-61. PMID: 17329619.
    View in: PubMed
  44. Lee MJ, Wang Y, Ricci MR, Sullivan S, Russell CD, Fried SK. Acute and chronic regulation of leptin synthesis, storage, and secretion by insulin and dexamethasone in human adipose tissue. Am J Physiol Endocrinol Metab. 2007 Mar; 292(3):E858-64. PMID: 17122089.
    View in: PubMed
  45. Varma V, Yao-Borengasser A, Rasouli N, Bodles AM, Phanavanh B, Lee MJ, Starks T, Kern LM, Spencer HJ, McGehee RE, Fried SK, Kern PA. Human visfatin expression: relationship to insulin sensitivity, intramyocellular lipids, and inflammation. J Clin Endocrinol Metab. 2007 Feb; 92(2):666-72. PMID: 17090638.
    View in: PubMed
  46. Lee MJ, Yang RZ, Gong DW, Fried SK. Feeding and insulin increase leptin translation. Importance of the leptin mRNA untranslated regions. J Biol Chem. 2007 Jan 5; 282(1):72-80. PMID: 17085442.
    View in: PubMed
  47. Yang RZ, Lee MJ, Hu H, Pollin TI, Ryan AS, Nicklas BJ, Snitker S, Horenstein RB, Hull K, Goldberg NH, Goldberg AP, Shuldiner AR, Fried SK, Gong DW. Acute-phase serum amyloid A: an inflammatory adipokine and potential link between obesity and its metabolic complications. PLoS Med. 2006 Jun; 3(6):e287. PMID: 16737350.
    View in: PubMed
  48. Lee MJ, Fried SK. Multilevel regulation of leptin storage, turnover, and secretion by feeding and insulin in rat adipose tissue. J Lipid Res. 2006 Sep; 47(9):1984-93. PMID: 16738357.
    View in: PubMed
  49. Yang RZ, Lee MJ, Hu H, Pray J, Wu HB, Hansen BC, Shuldiner AR, Fried SK, McLenithan JC, Gong DW. Identification of omentin as a novel depot-specific adipokine in human adipose tissue: possible role in modulating insulin action. Am J Physiol Endocrinol Metab. 2006 Jun; 290(6):E1253-61. PMID: 16531507.
    View in: PubMed
  50. Dourmashkin JT, Chang GQ, Hill JO, Gayles EC, Fried SK, Leibowitz SF. Model for predicting and phenotyping at normal weight the long-term propensity for obesity in Sprague-Dawley rats. Physiol Behav. 2006 Apr 15; 87(4):666-78. PMID: 16513148.
    View in: PubMed
  51. Li J, Bosch-Marce M, Nanayakkara A, Savransky V, Fried SK, Semenza GL, Polotsky VY. Altered metabolic responses to intermittent hypoxia in mice with partial deficiency of hypoxia-inducible factor-1alpha. Physiol Genomics. 2006 May 16; 25(3):450-7. PMID: 16507783.
    View in: PubMed
  52. Trujillo ME, Lee MJ, Sullivan S, Feng J, Schneider SH, Greenberg AS, Fried SK. Tumor necrosis factor alpha and glucocorticoid synergistically increase leptin production in human adipose tissue: role for p38 mitogen-activated protein kinase. J Clin Endocrinol Metab. 2006 Apr; 91(4):1484-90. PMID: 16403817.
    View in: PubMed
  53. Jobgen WS, Fried SK, Fu WJ, Meininger CJ, Wu G. Regulatory role for the arginine-nitric oxide pathway in metabolism of energy substrates. J Nutr Biochem. 2006 Sep; 17(9):571-88. PMID: 16524713.
    View in: PubMed
  54. Dourmashkin JT, Chang GQ, Gayles EC, Hill JO, Fried SK, Julien C, Leibowitz SF. Different forms of obesity as a function of diet composition. Int J Obes (Lond). 2005 Nov; 29(11):1368-78. PMID: 16088331.
    View in: PubMed
  55. Yun R, Dourmashkin JT, Hill J, Gayles EC, Fried SK, Leibowitz SF. PVN galanin increases fat storage and promotes obesity by causing muscle to utilize carbohydrate more than fat. Peptides. 2005 Nov; 26(11):2265-73. PMID: 15893855.
    View in: PubMed
  56. D'Eon TM, Souza SC, Aronovitz M, Obin MS, Fried SK, Greenberg AS. Estrogen regulation of adiposity and fuel partitioning. Evidence of genomic and non-genomic regulation of lipogenic and oxidative pathways. J Biol Chem. 2005 Oct 28; 280(43):35983-91. PMID: 16109719.
    View in: PubMed
  57. Ricci MR, Lee MJ, Russell CD, Wang Y, Sullivan S, Schneider SH, Brolin RE, Fried SK. Isoproterenol decreases leptin release from rat and human adipose tissue through posttranscriptional mechanisms. Am J Physiol Endocrinol Metab. 2005 Apr; 288(4):E798-804. PMID: 15585586.
    View in: PubMed
  58. Trujillo ME, Sullivan S, Harten I, Schneider SH, Greenberg AS, Fried SK. Interleukin-6 regulates human adipose tissue lipid metabolism and leptin production in vitro. J Clin Endocrinol Metab. 2004 Nov; 89(11):5577-82. PMID: 15531514.
    View in: PubMed
  59. Leibowitz SF, Dourmashkin JT, Chang GQ, Hill JO, Gayles EC, Fried SK, Wang J. Acute high-fat diet paradigms link galanin to triglycerides and their transport and metabolism in muscle. Brain Res. 2004 May 22; 1008(2):168-78. PMID: 15145753.
    View in: PubMed
  60. Wortley KE, Chang GQ, Davydova Z, Fried SK, Leibowitz SF. Cocaine- and amphetamine-regulated transcript in the arcuate nucleus stimulates lipid metabolism to control body fat accrual on a high-fat diet. Regul Pept. 2004 Feb 15; 117(2):89-99. PMID: 14700744.
    View in: PubMed
  61. Johnson JA, Albu JB, Engelson ES, Fried SK, Inada Y, Ionescu G, Kotler DP. Increased systemic and adipose tissue cytokines in patients with HIV-associated lipodystrophy. Am J Physiol Endocrinol Metab. 2004 Feb; 286(2):E261-71. PMID: 14532165.
    View in: PubMed
  62. Moreno DA, Ilic N, Poulev A, Brasaemle DL, Fried SK, Raskin I. Inhibitory effects of grape seed extract on lipases. Nutrition. 2003 Oct; 19(10):876-9. PMID: 14559324.
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  63. Fried SK, Rao SP. Sugars, hypertriglyceridemia, and cardiovascular disease. Am J Clin Nutr. 2003 Oct; 78(4):873S-880S. PMID: 14522752.
    View in: PubMed
  64. Wang Y, Sullivan S, Trujillo M, Lee MJ, Schneider SH, Brolin RE, Kang YH, Werber Y, Greenberg AS, Fried SK. Perilipin expression in human adipose tissues: effects of severe obesity, gender, and depot. Obes Res. 2003 Aug; 11(8):930-6. PMID: 12917496.
    View in: PubMed
  65. Boden G, Cheung P, Mozzoli M, Fried SK. Effect of thiazolidinediones on glucose and fatty acid metabolism in patients with type 2 diabetes. Metabolism. 2003 Jun; 52(6):753-9. PMID: 12800103.
    View in: PubMed
  66. Dark J, Miller DR, Lewis DA, Fried SK, Bunkin D. Noradrenaline-induced lipolysis in adipose tissue is suppressed at hibernation temperatures in ground squirrels. J Neuroendocrinol. 2003 May; 15(5):451-8. PMID: 12694370.
    View in: PubMed
  67. Laferrère B, Caixas A, Fried SK, Bashore C, Kim J, Pi-Sunyer FX. A pulse of insulin and dexamethasone stimulates serum leptin in fasting human subjects. Eur J Endocrinol. 2002 Jun; 146(6):839-45. PMID: 12039705.
    View in: PubMed
  68. Russell CD, Ricci MR, Brolin RE, Magill E, Fried SK. Regulation of the leptin content of obese human adipose tissue. Am J Physiol Endocrinol Metab. 2001 Mar; 280(3):E399-404. PMID: 11171593.
    View in: PubMed
  69. Johnson JA, Fried SK, Pi-Sunyer FX, Albu JB. Impaired insulin action in subcutaneous adipocytes from women with visceral obesity. Am J Physiol Endocrinol Metab. 2001 Jan; 280(1):E40-9. PMID: 11120657.
    View in: PubMed
  70. Fried SK, Moustaid-Moussa N. Culture of adipose tissue and isolated adipocytes. Methods Mol Biol. 2001; 155:197-212. PMID: 11293072.
    View in: PubMed
  71. Fried SK, Ricci MR, Russell CD, Laferrère B. Regulation of leptin production in humans. J Nutr. 2000 Dec; 130(12):3127S-3131S. PMID: 11110887.
    View in: PubMed
  72. Laferrère B, Fried SK, Osborne T, Pi-Sunyer FX. Effect of one morning meal and a bolus of dexamethasone on 24-hour variation of serum leptin levels in humans. Obes Res. 2000 Oct; 8(7):481-6. PMID: 11068953.
    View in: PubMed
  73. Weber RV, Buckley MC, Fried SK, Kral JG. Subcutaneous lipectomy causes a metabolic syndrome in hamsters. Am J Physiol Regul Integr Comp Physiol. 2000 Sep; 279(3):R936-43. PMID: 10956251.
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  74. Shaughnessy S, Smith ER, Kodukula S, Storch J, Fried SK. Adipocyte metabolism in adipocyte fatty acid binding protein knockout mice (aP2-/-) after short-term high-fat feeding: functional compensation by the keratinocyte [correction of keritinocyte] fatty acid binding protein. Diabetes. 2000 Jun; 49(6):904-11. PMID: 10866041.
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  75. Ricci MR, Fried SK, Mittleman KD. Acute cold exposure decreases plasma leptin in women. Metabolism. 2000 Apr; 49(4):421-3. PMID: 10778861.
    View in: PubMed
  76. Edens NK, Moshirfar A, Potter GM, Fried SK, Castonguay TW. Adrenalectomy reduces adiposity by decreasing food efficiency, not direct effects on white adipose tissue. Obes Res. 1999 Jul; 7(4):395-401. PMID: 10440596.
    View in: PubMed
  77. Ricci MR, Fried SK. Isoproterenol decreases leptin expression in adipose tissue of obese humans. Obes Res. 1999 May; 7(3):233-40. PMID: 10348493.
    View in: PubMed
  78. Wang Y, Fried SK, Petersen RN, Schoknecht PA. Somatotropin regulates adipose tissue metabolism in neonatal swine. J Nutr. 1999 Jan; 129(1):139-45. PMID: 9915890.
    View in: PubMed
  79. Laferrère B, Fried SK, Hough K, Campbell SA, Thornton J, Pi-Sunyer FX. Synergistic effects of feeding and dexamethasone on serum leptin levels. J Clin Endocrinol Metab. 1998 Oct; 83(10):3742-5. PMID: 9768694.
    View in: PubMed
  80. Russell CD, Petersen RN, Rao SP, Ricci MR, Prasad A, Zhang Y, Brolin RE, Fried SK. Leptin expression in adipose tissue from obese humans: depot-specific regulation by insulin and dexamethasone. Am J Physiol. 1998 Sep; 275(3 Pt 1):E507-15. PMID: 9725819.
    View in: PubMed
  81. Lee JJ, Smith PJ, Fried SK. Mechanisms of decreased lipoprotein lipase activity in adipocytes of starved rats depend on duration of starvation. J Nutr. 1998 Jun; 128(6):940-6. PMID: 9614151.
    View in: PubMed
  82. Fried SK, Bunkin DA, Greenberg AS. Omental and subcutaneous adipose tissues of obese subjects release interleukin-6: depot difference and regulation by glucocorticoid. J Clin Endocrinol Metab. 1998 Mar; 83(3):847-50. PMID: 9506738.
    View in: PubMed
  83. Papaspyrou-Rao S, Schneider SH, Petersen RN, Fried SK. Dexamethasone increases leptin expression in humans in vivo. J Clin Endocrinol Metab. 1997 May; 82(5):1635-7. PMID: 9141563.
    View in: PubMed
  84. Dowling HJ, Fried SK, Pi-Sunyer FX. Insulin resistance in adipocytes of obese women: effects of body fat distribution and race. Metabolism. 1995 Aug; 44(8):987-95. PMID: 7637656.
    View in: PubMed
  85. Fried SK, Russell CD, Grauso NL, Brolin RE. Lipoprotein lipase regulation by insulin and glucocorticoid in subcutaneous and omental adipose tissues of obese women and men. J Clin Invest. 1993 Nov; 92(5):2191-8. PMID: 8227334.
    View in: PubMed
  86. Fried SK, Leibel RL, Edens NK, Kral JG. Lipolysis in intraabdominal adipose tissues of obese women and men. Obes Res. 1993 Nov; 1(6):443-8. PMID: 16353332.
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  87. Haubenwallner S, Hörl G, Shachter NS, Presta E, Fried SK, Höfler G, Kostner GM, Breslow JL, Zechner R. A novel missense mutation in the gene for lipoprotein lipase resulting in a highly conservative amino acid substitution (Asp180-->Glu) causes familial chylomicronemia (type I hyperlipoproteinemia). Genomics. 1993 Nov; 18(2):392-6. PMID: 8288243.
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  88. Edens NK, Fried SK, Kral JG, Hirsch J, Leibel RL. In vitro lipid synthesis in human adipose tissue from three abdominal sites. Am J Physiol. 1993 Sep; 265(3 Pt 1):E374-9. PMID: 8214046.
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  89. Digirolamo M, Thacker SV, Fried SK. Effects of cell density on in vitro glucose metabolism by isolated adipocytes. Am J Physiol. 1993 Mar; 264(3 Pt 1):E361-6. PMID: 8460683.
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  90. Fried SK, Appel B, Zechner R. Interleukin 1 alpha decreases the synthesis and activity of lipoprotein lipase in human adipose tissue. Horm Metab Res. 1993 Feb; 25(2):129-30. PMID: 7681421.
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  91. Appel B, Fried SK. Effects of insulin and dexamethasone on lipoprotein lipase in human adipose tissue. Am J Physiol. 1992 May; 262(5 Pt 1):E695-9. PMID: 1590379.
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  92. Fried SK, Turkenkopf IJ, Goldberg IJ, Doolittle MH, Kirchgessner TG, Schotz MC, Johnson PR, Greenwood MR. Mechanisms of increased lipoprotein lipase in fat cells of obese Zucker rats. Am J Physiol. 1991 Nov; 261(5 Pt 1):E653-60. PMID: 1951692.
    View in: PubMed
  93. Zechner R, Moser R, Newman TC, Fried SK, Breslow JL. Apolipoprotein E gene expression in mouse 3T3-L1 adipocytes and human adipose tissue and its regulation by differentiation and lipid content. J Biol Chem. 1991 Jun 5; 266(16):10583-8. PMID: 1709937.
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  94. Watford M, Fried SK. Adipose tissue metabolism can now be directly studied in vivo. Trends Biochem Sci. 1991 Jun; 16(6):201-2. PMID: 1891799.
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  95. Noguchi Y, Vydelingum NA, Younes RN, Fried SK, Brennan MF. Tumor-induced alterations in tissue lipoprotein lipase activity and mRNA levels. Cancer Res. 1991 Feb 1; 51(3):863-9. PMID: 1988126.
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  96. Fried SK, Velazquez N, Nobel J. Nutrition-induced variations in responsiveness to insulin effects on lipoprotein lipase activity in isolated rat fat cells. J Nutr. 1990 Sep; 120(9):1087-95. PMID: 2204695.
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  97. Fried SK, Zechner R. Cachectin/tumor necrosis factor decreases human adipose tissue lipoprotein lipase mRNA levels, synthesis, and activity. J Lipid Res. 1989 Dec; 30(12):1917-23. PMID: 2695592.
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  98. Hirsch J, Fried SK, Edens NK, Leibel RL. The fat cell. Med Clin North Am. 1989 Jan; 73(1):83-96. PMID: 2643010.
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  99. Leibel RL, Edens NK, Fried SK. Physiologic basis for the control of body fat distribution in humans. Annu Rev Nutr. 1989; 9:417-43. PMID: 2669880.
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  100. Fried SK, Kral JG. Adipose tissue of morbidly obese patients: clinical implications of distribution, morphology, and metabolism. Gastroenterol Clin North Am. 1987 Jun; 16(2):207-13. PMID: 3319901.
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  101. Vasselli JR, Flory T, Fried SK. Insulin binding and glucose transport in adipocytes of acarbose-treated Zucker lean and obese rats. Int J Obes. 1987; 11 Suppl 3:71-5. PMID: 3326849.
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  102. Fried SK, Kral JG. Sex differences in regional distribution of fat cell size and lipoprotein lipase activity in morbidly obese patients. Int J Obes. 1987; 11(2):129-40. PMID: 3610466.
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  103. Fried SK, DiGirolamo M. Lipoprotein lipase secretion from isolated rat fat cells of different size. Life Sci. 1986 Dec 1; 39(22):2111-9. PMID: 3784772.
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  104. Hill JO, Fried SK, DiGirolamo M. Effects of fasting and restricted refeeding on utilization of ingested energy in rats. Am J Physiol. 1984 Aug; 247(2 Pt 2):R318-27. PMID: 6465347.
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  105. Fried SK, Hill JO, Nickel M, DiGirolamo M. Novel regulation of lipoprotein lipase activity in rat brown adipose tissue: effects of fasting and caloric restriction during refeeding. J Nutr. 1983 Sep; 113(9):1870-4. PMID: 6886829.
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  106. Fried SK, Hill JO, Nickel M, DiGirolamo M. Prolonged effects of fasting-refeeding on rat adipose tissue lipoprotein lipase activity: influence of caloric restriction during refeeding. J Nutr. 1983 Sep; 113(9):1861-9. PMID: 6886828.
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  107. Hill JO, Fried SK, DiGirolamo M. Effects of a high-fat diet on energy intake and expenditure in rats. Life Sci. 1983 Jul 11; 33(2):141-9. PMID: 6865651.
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  108. Crandall DL, Fried SK, Francendese AA, Nickel M, DiGirolamo M. Lactate release from isolated rat adipocytes: influence of cell size, glucose concentration, insulin and epinephrine. Horm Metab Res. 1983 Jul; 15(7):326-9. PMID: 6350139.
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  109. Fried SK, Lavau M, Pi-Sunyer FX. Variations of glucose metabolism by fat cells from three adipose depots of the rat. Metabolism. 1982 Sep; 31(9):876-83. PMID: 7121259.
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  110. Fried SK, Lavau M, Pi-Sunyer FX. Role of fatty acid synthesis in the control of insulin-stimulated glucose utilization by rat adipocytes. J Lipid Res. 1981 Jul; 22(5):753-62. PMID: 7026709.
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  111. Lavau M, Fried SK, Susini C, Freychet P. Mechanism of insulin resistance in adipocytes of rats fed a high-fat diet. J Lipid Res. 1979 Jan; 20(1):8-16. PMID: 438656.
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