Mike Jager
Pre-Doctoral Trainee
Boston University School of Medicine, Division of Graduate Medical Sciences
Dept of Biochemistry

My thesis project is focused on describing a novel mediator of fibrosis in adipose tissue and characterizing extracellular matrix remodeling that occurs with adipose tissue fibrosis.

• I have validated a novel mediator (Aortic Carboxypeptidase-Like Protein) of metabolic diseases (type II diabetes, morbid obesity etc.,) for targeting by therapeutics.
• I have developed and refined an ex vivo tissue system to develop rapid adipose tissue fibrosis to understand the composition, mechanical and structural properties of adipose tissue fibrosis as well as the impact on non pathogenic cells in the tissue.

Scientific techniques employed include confocal microscopy, nanoindentation, immunofluorescence, immunohistochemistry, fluorescence activated cell sorting, tissue culture techniques, in vivo studies (mouse) and molecular biology techniques (Western blot, PCR, qPCR etc.,).
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

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