Andrea Havasi, MD
Assistant Professor
Boston University School of Medicine
Dept of Medicine
Nephrology

MD, Semmelweis University



Andrea Havasi, M.D. is an Assistant Professor of Medicine at Boston University. She is board certified in Internal Medicine and Nephrology. As a recipient of the National Kidney Foundation Research Fellow Award, she undertook research training at BMC investigating the cytoprotective mechanisms of heat shock proteins in ischemic renal cell injury and apoptosis. She joined the Renal Section Faculty in 2008, and continues basic and translational research in the area of renal cell injury and proteinuric kidney diseases using cell culture and animal models. She is the recipient of the American Heart Association Scientist Development Grant and NIH K08 award. Dr. Havasi is the Co-Director of the Mitochondria Research Affinity Collaborative (mtARC) at the Boston University School of Medicine. Her clinical roles include a weekly clinic and attending time on the consult and dialysis/transplant services.

Current research interest: Proteinuria and renal fibrosis
Mechanisms of proteinuria induced tubular damage, interstitial fibrosis and inflammation in progressive kidney diseases.
Proteinuria is associated with progressive chronic kidney disease. It is well known that exposure of proximal tubular epithelial cells to large amounts of albumin leads to the development of tubular atrophy and fibrosis. However, the possible pathogenic role of albumin in this process has not been fully elucidated. Development of new therapeutic tools to prevent or slow the progression of proteinuric chronic kidney disease requires clear understanding of the effect of proteinuria on tubular cell function.

Active Staff Hospital Privileges
Boston Medical Center
Medicine





Proteinuria Causes Progressive Kidney Disease by Impairing Autophagy
07/15/2011 - 10/31/2016 (PI)
NIH-NIDDK

Proteinuria causes progressive kidney disease by impairing autophagy
01/01/2011 - 02/28/2014 (PI)
American Heart Assoc

HSP70 As a Cytoprotective Protein: Interaction with the ACL2 Family
07/01/2005 - 06/30/2008 (PI)
National Kidney Fdtn


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Wang Z, Gall JM, Bonegio R, Havasi A, Illanes K, Schwartz JH, Borkan SC. Correction for Wang et al., "Nucleophosmin, a Critical Bax Cofactor in Ischemia-Induced Cell Death". Mol Cell Biol. 2017 Oct 01; 37(19).View Related Profiles. PMID: 28899998.
  2. Batalini F, Econimo L, Quillen K, Sloan JM, Sarosiek S, Brauneis D, Havasi A, Stern L, Dember LM, Sanchorawala V. High-Dose Melphalan and Stem Cell Transplantation in Patients on Dialysis Due to Immunoglobulin Light-Chain Amyloidosis and Monoclonal Immunoglobulin Deposition Disease. Biol Blood Marrow Transplant. 2017 Sep 01.View Related Profiles. PMID: 28865972.
  3. Havasi A, Lu W, Cohen HT, Beck L, Wang Z, Igwebuike C, Borkan SC. Blocking peptides and molecular mimicry as treatment for kidney disease. Am J Physiol Renal Physiol. 2017 Jun 01; 312(6):F1016-F1025.View Related Profiles. PMID: 27654896; DOI: 10.1152/ajprenal.00601.2015;.
  4. Menn-Josephy H, Lee CS, Nolin A, Christov M, Rybin DV, Weinberg JM, Henderson J, Bonegio R, Havasi A. Renal Interstitial Fibrosis: An Imperfect Predictor of Kidney Disease Progression in Some Patient Cohorts. Am J Nephrol. 2016; 44(4):289-299.View Related Profiles. PMID: 27626625.
  5. Nolin AC, Mulhern RM, Panchenko MV, Pisarek-Horowitz A, Wang Z, Shirihai O, Borkan SC, Havasi A. Proteinuria causes dysfunctional autophagy in the proximal tubule. Am J Physiol Renal Physiol. 2016 Dec 01; 311(6):F1271-F1279. PMID: 27582098; DOI: 10.1152/ajprenal.00125.2016;.
  6. Havasi A, Stern L, Lo S, Sun F, Sanchorawala V. Validation of new renal staging system in AL amyloidosis treated with high dose melphalan and stem cell transplantation. Am J Hematol. 2016 Oct; 91(10):E458-60.View Related Profiles. PMID: 27356490; DOI: 10.1002/ajh.24464;.
  7. Havasi A, Dong Z. Autophagy and Tubular Cell Death in the Kidney. Semin Nephrol. 2016 May; 36(3):174-88. PMID: 27339383; PMCID: PMC4920968; DOI: 10.1016/j.semnephrol.2016.03.005;.
  8. Bever KM, Masha LI, Sun F, Stern L, Havasi A, Berk JL, Sanchorawala V, Seldin DC, Sloan JM. Risk factors for venous thromboembolism in immunoglobulin light chain amyloidosis. Haematologica. 2016 Jan; 101(1):86-90.View Related Profiles. PMID: 26452981; PMCID: PMC4697895; DOI: 10.3324/haematol.2015.133900;.
  9. Stern L, Havasi A. Renal transplantation in amyloidosis and MIDD. Front Biosci (Elite Ed). 2015; 7:149-57.View Related Profiles. PMID: 25553370.
  10. Gall JM, Wang Z, Bonegio RG, Havasi A, Liesa M, Vemula P, Borkan SC. Conditional knockout of proximal tubule mitofusin 2 accelerates recovery and improves survival after renal ischemia. J Am Soc Nephrol. 2015 May; 26(5):1092-102.View Related Profiles. PMID: 25201884; PMCID: PMC4413756; DOI: 10.1681/ASN.2014010126;.
Showing 10 of 26 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 26 publications over 13 distinct years, with a maximum of 5 publications in 2016

YearPublications
20011
20042
20051
20081
20092
20101
20113
20122
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20142
20152
20165
20172
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Proteinuric renal disease

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