J. Michael Gaziano, MD
Adjunct Professor
Boston University Chobanian & Avedisian School of Medicine
Medicine
Cardiovascular Medicine

MD, Yale University School of Medicine
MPH, Harvard School of Public Health
BA, West Virginia University



Dr. Michael J. Gaziano, MD, MPH is an internationally recognized chronic disease epidemiologist and trialist. He received his MD from Yale Medical School and his MPH from the Harvard School of Public Health.

At the VA Boston Healthcare System, he is one of the Director the Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), a national epidemiology and trial center funded by CSR&D where he directs the epidemiology research center. He is national PI for the Million Veteran Program (MVP), a large project designed to enroll a million veterans into a large observational cohort with stored biospecimens. He also serves as the director of the Boston Geriatric Research and Education Center (GRECC). At VA Boston he runs a preventive cardiology program with an associated fellowship. He is the Chief of the Division of Aging at Brigham and Women’s Hospital where he is principal investigator for the ongoing Physicians' Health Study (PHS) II study, a large-scale trial of vitamins in the prevention of chronic disease. The Physicians’ Health Study cohort is comprised of 29,000 physicians who have been followed for up to 28 years. He is a Professor of Medicine at Harvard Medical School.

Dr. Gaziano’s research interests include the epidemiology of chronic diseases, with a particular interest in the roles that individual lifestyle choices (diet, exercise, smoking), metabolic factors (obesity, high cholesterol, and hypertension), and biochemical and genetic markers play on the risk of coronary artery disease and stroke. Also of interest is the impact that vascular disease has on other organ systems. Recently, Dr. Gaziano has initiated a number of research projects to investigate the diverse nature of atherosclerosis. While atherosclerosis plaques form only in certain large and medium-sized vessels, the process of atherogenesis affects arteries of all sizes. For example, renal dysfunction, cognitive decline and osteoporosis-related fractures have been linked to various cardiovascular disease risk factors, suggesting a role for small vessel disease in vascular dementia, in abnormal bone remodeling and chronic renal disease. These projects are intended to explore the extent to which atherosclerotic disease in small vessels leads to these and other chronic conditions.

He has published over 350 original reports, reviews, book chapters, and books. He teaches advanced epidemiology and has mentored over 50 trainees. He is a contributing editor for JAMA.

VA Boston Healthcare System






Title
Physicians Health Study II: Prevention Trial of Vitamins
(PI)

Genomics of Posttraumatic Stress Disorder in Veterans
(PI)

Influenza Vaccine to Effectively Stop Cardio-thoracic Events and Decompensated Heart Failure (INVESTED)
(PI)

The Million Veteran Program (MVP) R&D#10286-C
(PI)

CSP Epidemiology Research and Information Center (ERIC)
(PI)

Veteran Genetics and Health Referent Cohort
(PI)



Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Rahafrooz M, Elbers DC, Gopal JR, Ren J, Chan NH, Yildirim C, Desai AS, Santos AA, Murray K, Havighurst T, Udell JA, Farkouh ME, Cooper L, Gaziano JM, Vardeny O, Mao L, Kim K, Gagnon DR, Solomon SD, Joseph J. Effectiveness of electronic medical record-based strategies for death and hospital admission endpoint capture in pragmatic clinical trials. J Am Med Inform Assoc. 2025 Feb 01; 32(2):349-356.View Related Profiles. PMID: 39671451; PMCID: PMC11756702; DOI: 10.1093/jamia/ocae303;
     
  2. Clarke SL, Huang RDL, Hilliard AT, Levin MG, Sharma D, Thomson B, Lynch J, Tsao PS, Gaziano JM, Assimes TL. Genetically predicted lipoprotein(a) associates with coronary artery plaque severity independent of low-density lipoprotein cholesterol. Eur J Prev Cardiol. 2025 Jan 27; 32(2):116-127. PMID: 39158116
     
  3. Wen J, Xue H, Rush E, Panickan VA, Cai T, Zhou D, Ho YL, Costa L, Begoli E, Hong C, Gaziano JM, Cho K, Liao KP, Lu J, Cai T. DOME: Directional medical embedding vectors from Electronic Health Records. J Biomed Inform. 2025 Feb; 162:104768. PMID: 39755324
     
  4. Weng LC, Rämö JT, Jurgens SJ, Khurshid S, Chaffin M, Hall AW, Morrill VN, Wang X, Nauffal V, Sun YV, Beer D, Lee S, Nadkarni GN, Duong T, Wang B, Czuba T, Austin TR, Yoneda ZT, Friedman DJ, Clayton A, Hyman MC, Judy RL, Skanes AC, Orland KM, Treu TM, Oetjens MT, Alonso A, Soliman EZ, Lin H, Lunetta KL, van der Pals J, Issa TZ, Nafissi NA, May HT, Leong-Sit P, Roselli C, Choi SH, Khan HR, Knight S, Karlsson Linnér R, Bezzina CR, Ripatti S, Heckbert SR, Gaziano JM, Loos RJF, Psaty BM, Smith JG, Benjamin EJ, Arking DE, Rader DJ, Shah SH, Roden DM, Damrauer SM, Eckhardt LL, Roberts JD, Cutler MJ, Shoemaker MB, Haggerty CM, Cho K, Palotie A, Wilson PWF, Ellinor PT, Lubitz SA. The impact of common and rare genetic variants on bradyarrhythmia development. Nat Genet. 2025 Jan; 57(1):53-64.View Related Profiles. PMID: 39747593
     
  5. Larsen JR, Zheng C, La J, Wu JT, Kelley M, Gaziano JM, Brophy M, Do NV, Kim DH, Driver JA, Dumontier C, Fillmore NR. Multimorbidity and Its Impact in Older United States Veterans Newly Treated for Advanced Non-Small Cell Lung Cancer. Ann Am Thorac Soc. 2024 Dec 16.View Related Profiles. PMID: 39680869
     
  6. Dulberger KN, La J, Li A, Lotfollahzadeh S, Jose A, Do NV, Brophy MT, Gaziano JM, Ravid K, Chitalia VC, Fillmore NR. External validation of a novel cancer-associated venous thromboembolism risk assessment score in a safety-net hospital. Res Pract Thromb Haemost. 2025 Jan; 9(1):102650.View Related Profiles. PMID: 39839661; PMCID: PMC11745955; DOI: 10.1016/j.rpth.2024.102650;
     
  7. Gorman BR, Voloudakis G, Igo RP, Kinzy T, Halladay CW, Bigdeli TB, Zeng B, Venkatesh S, Cooke Bailey JN, Crawford DC, Markianos K, Dong F, Schreiner PA, Zhang W, Hadi T, Anger MD, Stockwell A, Melles RB, Yin J, Choquet H, Kaye R, Patasova K, Patel PJ, Yaspan BL, Jorgenson E, Hysi PG, Lotery AJ, Gaziano JM, Tsao PS, Fliesler SJ, Sullivan JM, Greenberg PB, Wu WC, Assimes TL, Pyarajan S, Roussos P, Peachey NS, Iyengar SK. Genome-wide association analyses identify distinct genetic architectures for age-related macular degeneration across ancestries. Nat Genet. 2024 Dec; 56(12):2659-2671. PMID: 39623103
     
  8. Nguyen XT, Li Y, Gong Y, Houghton S, Ho YL, Pyatt M, Treu T, Li R, Akinosho K, Raghavan S, Gagnon DR, Gaziano JM, Wilson PWF, Cho K. Cardiovascular Health Score and Atherosclerotic Cardiovascular Disease in the Million Veteran Program. JAMA Netw Open. 2024 Dec 02; 7(12):e2447902.View Related Profiles. PMID: 39641929; PMCID: PMC11624584; DOI: 10.1001/jamanetworkopen.2024.47902;
     
  9. Wang L, Cook NR, Manson JE, Gaziano JM, Buring JE, Sesso HD. Associations of Vitamin D-Related Biomarkers With Hypertension and the Renin-Angiotensin System in Men and Women. Am J Hypertens. 2024 Nov 15; 37(12):953-961.View Related Profiles. PMID: 39120701; PMCID: PMC11565204; DOI: 10.1093/ajh/hpae103;
     
  10. Steele L, Quaden R, Ahmed ST, Harrington KM, Duong LM, Ko J, Gifford EJ, Polimanti R, Gaziano JM, Aslan M, Helmer DA, Hauser ER. Association of deployment characteristics and exposures with persistent ill health among 1990-1991 Gulf War veterans in the VA Million Veteran Program. Environ Health. 2024 Oct 25; 23(1):92.View Related Profiles. PMID: 39456027; PMCID: PMC11520114; DOI: 10.1186/s12940-024-01118-7;
     
Showing 10 of 754 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 753 publications over 36 distinct years, with a maximum of 47 publications in 2022 and 2024

YearPublications
19902
19911
19921
19937
19942
19958
199617
19976
19984
199912
20009
200111
20028
200315
200417
200523
200623
200733
200840
200924
201025
201131
201245
201329
201427
201528
201625
201714
201827
201937
202020
202138
202247
202346
202447
20254

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