Emily Wan | Profiles RNS

Emily S. Wan, MD

Adjunct Assistant Professor

Boston University Chobanian & Avedisian School of Medicine

Medicine

Pulmonary, Allergy, Sleep & Critical Care Medicine

MD, State University of New York at Stony Brook

Websites

	ResearchGate
	Brigham and Women's Profile
	Mass General Brigham Profile
	Harvard Catalyst
	Pri-med

Dr. Wan is a graduate of Yale University and the State University of New York Downstate Medical Center. She completed her internship and residency at Massachusetts General Hospital followed by fellowship training in the Harvard Combined Pulmonary and Critical Care Program. She is currently an Assistant Professor of Medicine at Harvard Medical School and attends in the ICU and inpatient and outpatient pulmonary services at VA Boston and Brigham and Women's Hospital. Her research interests include the epidemiology, genetics, and genomics of COPD. She is a member of the Genetics Analysis Core of the COPDGene Study and is the principal investigator of research grants from the Alpha-1 Foundation and a Career Development Award 2 from the Veterans Administration.

VA Boston Healthcare System

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Maccarone JR, Sterns OR, Timmons A, Korpak AM, Smith NL, Nakayama KS, Baird CP, Ciminera P, Kheradmand F, Fan VS, Hart JE, Koutrakis P, Jerrett M, Kuschner WG, Ioachimescu OC, Montgrain PR, Proctor SP, Redlich CA, Wendt CH, Blanc PD, Garshick E, Wan ES. Deployment-related Cigarette Smoking Behaviors and Pulmonary Function Among U.S. Veterans. Mil Med. 2024 Mar 25.View Related Profiles.

Wan, Emily
Garshick, Eric

PMID: 38536226

Garshick E, Redlich CA, Korpak A, Timmons AK, Smith NL, Nakayama K, Baird CP, Ciminera P, Kheradmand F, Fan VS, Hart JE, Koutrakis P, Kuschner W, Ioachimescu O, Jerrett M, Montgrain PR, Proctor SP, Wan ES, Wendt CH, Wongtrakool C, Blanc PD. Chronic respiratory symptoms following deployment-related occupational and environmental exposures among US veterans. Occup Environ Med. 2024 Feb 02; 81(2):59-65.View Related Profiles.

Wan, Emily
Garshick, Eric

PMID: 37968126; PMCID: PMC10872566; DOI: 10.1136/oemed-2023-109146;

Higbee DH, Lirio A, Hamilton F, Granell R, Wyss AB, London SJ, Bartz TM, Gharib SA, Cho MH, Wan E, Silverman E, Crapo JD, Lominchar JVT, Hansen T, Grarup N, Dantoft T, Kårhus L, Linneberg A, O'Connor GT, Dupuis J, Xu H, De Vries MM, Hu X, Rich SS, Barr RG, Manichaikul A, Wijnant SRA, Brusselle GG, Lahousse L, Li X, Hernández Cordero AI, Obeidat M, Sin DD, Harris SE, Redmond P, Taylor AM, Cox SR, Williams AT, Shrine N, John C, Guyatt AL, Hall IP, Davey Smith G, Tobin MD, Dodd JW. Genome-wide association study of preserved ratio impaired spirometry (PRISm). Eur Respir J. 2024 Jan; 63(1).View Related Profiles.

Wan, Emily
O'Connor, George
Dupuis, Josee

PMID: 38097206; PMCID: PMC10765494; DOI: 10.1183/13993003.00337-2023;

Bamonti PM, Perndorfer C, Robinson SA, Mongiardo MA, Wan ES, Moy ML. Depression Symptoms and Physical Activity in Veterans With COPD: Insights From a Web-Based, Pedometer-Mediated Physical Activity Intervention. Ann Behav Med. 2023 Sep 13; 57(10):855-865.View Related Profiles.

Wan, Emily
Moy, Marilyn
Robinson, Stephanie

PMID: 37260290

Wan ES. Sharing More Than Space: The Heart and Lungs. Chest. 2023 Sep; 164(3):566-567. PMID: 37689465

Labaki WW, Gu T, Murray S, Curtis JL, Wells JM, Bhatt SP, Bon J, Diaz AA, Hersh CP, Wan ES, Kim V, Beaty TH, Hokanson JE, Bowler RP, Arenberg DA, Kazerooni EA, Martinez FJ, Silverman EK, Crapo JD, Make BJ, Regan EA, Han MK. Causes of and Clinical Features Associated with Death in Tobacco Cigarette Users by Lung Function Impairment. Am J Respir Crit Care Med. 2023 Aug 15; 208(4):451-460. PMID: 37159910; PMCID: PMC10449063; DOI: 10.1164/rccm.202210-1887OC;

Van Buren E, Radicioni G, Lester S, O'Neal WK, Dang H, Kasela S, Garudadri S, Curtis JL, Han MK, Krishnan JA, Wan ES, Silverman EK, Hastie A, Ortega VE, Lappalainen T, Nawijn MC, Berge MVD, Christenson SA, Li Y, Cho MH, Kesimer M, Kelada SNP. Genetic regulators of sputum mucin concentration and their associations with COPD phenotypes. PLoS Genet. 2023 Jun; 19(6):e1010445. PMID: 37352370; PMCID: PMC10325042; DOI: 10.1371/journal.pgen.1010445;

Tran TV, Kinney GL, Comellas A, Hoth KF, Baldomero AK, Mamary AJ, Curtis JL, Hanania N, Casaburi R, Young KA, Kim V, Make B, Wan ES, Diaz AA, Hokanson J, Crapo JD, Silverman EK, Bhatt SP, Regan E, Fortis S. Prevalence of abnormal spirometry in individuals with a smoking history and no known obstructive lung disease. Respir Med. 2023 Mar; 208:107126. PMID: 36717002; PMCID: PMC9990311; DOI: 10.1016/j.rmed.2023.107126;

Wan ES, Verma A, Minnier J, Luoh SW, Iyengar SK. Reply to: Sookaromdee and Wiwanitkit. Am J Respir Crit Care Med. 2023 Jan 01; 207(1):113-114. PMID: 36041210; PMCID: PMC9952861; DOI: 10.1164/rccm.202208-1611LE;

Verma A, Minnier J, Wan ES, Huffman JE, Gao L, Joseph J, Ho YL, Wu WC, Cho K, Gorman BR, Rajeevan N, Pyarajan S, Garcon H, Meigs JB, Sun YV, Reaven PD, McGeary JE, Suzuki A, Gelernter J, Lynch JA, Petersen JM, Zekavat SM, Natarajan P, Dalal S, Jhala DN, Arjomandi M, Gatsby E, Lynch KE, Bonomo RA, Freiberg M, Pathak GA, Zhou JJ, Donskey CJ, Madduri RK, Wells QS, Huang RDL, Polimanti R, Chang KM, Liao KP, Tsao PS, Wilson PWF, Hung AM, O'Donnell CJ, Gaziano JM, Hauger RL, Iyengar SK, Luoh SW. A MUC5B Gene Polymorphism, rs35705950-T, Confers Protective Effects Against COVID-19 Hospitalization but Not Severe Disease or Mortality. Am J Respir Crit Care Med. 2022 Nov 15; 206(10):1220-1229.View Related Profiles.

O'Donnell, Christopher
Wan, Emily
Gaziano, J. Michael

PMID: 35771531; PMCID: PMC9746845; DOI: 10.1164/rccm.202109-2166OC;

Showing 10 of 71 results. Show More

Wan ES, Polak M, Goldstein RL, Lazzari AA, Kantorowski A, Garshick E, Moy ML. Physical Activity, Exercise Capacity, and Body Composition in U.S. Veterans with Chronic Obstructive Pulmonary Disease. Ann Am Thorac Soc. 2022 Oct; 19(10):1669-1676.View Related Profiles.

Lazzari, Antonio
Wan, Emily
Garshick, Eric
Moy, Marilyn

PMID: 35536690

Wan ES. The Clinical Spectrum of PRISm. Am J Respir Crit Care Med. 2022 09 01; 206(5):524-525. PMID: 35612910; PMCID: PMC9716910; DOI: 10.1164/rccm.202205-0965ED;

Verma A, Huffman JE, Gao L, Minnier J, Wu WC, Cho K, Ho YL, Gorman BR, Pyarajan S, Rajeevan N, Garcon H, Joseph J, McGeary JE, Suzuki A, Reaven PD, Wan ES, Lynch JA, Petersen JM, Meigs JB, Freiberg MS, Gatsby E, Lynch KE, Zekavat SM, Natarajan P, Dalal S, Jhala DN, Arjomandi M, Bonomo RA, Thompson TK, Pathak GA, Zhou JJ, Donskey CJ, Madduri RK, Wells QS, Gelernter J, Huang RDL, Polimanti R, Chang KM, Liao KP, Tsao PS, Sun YV, Wilson PWF, O'Donnell CJ, Hung AM, Gaziano JM, Hauger RL, Iyengar SK, Luoh SW. Association of Kidney Comorbidities and Acute Kidney Failure With Unfavorable Outcomes After COVID-19 in Individuals With the Sickle Cell Trait. JAMA Intern Med. 2022 Aug 01; 182(8):796-804.View Related Profiles.

O'Donnell, Christopher
Wan, Emily
Gaziano, J. Michael

PMID: 35759254; PMCID: PMC9237798; DOI: 10.1001/jamainternmed.2022.2141;

Bamonti PM, Robinson SA, Wan ES, Moy ML. Improving Physiological, Physical, and Psychological Health Outcomes: A Narrative Review in US Veterans with COPD. Int J Chron Obstruct Pulmon Dis. 2022; 17:1269-1283.View Related Profiles.

Wan, Emily
Moy, Marilyn
Robinson, Stephanie

PMID: 35677347; PMCID: PMC9167842; DOI: 10.2147/COPD.S339323;

Cruz Rivera PN, Goldstein RL, Polak M, Lazzari AA, Moy ML, Wan ES. Performance of bioelectrical impedance analysis compared to dual X-ray absorptiometry (DXA) in Veterans with COPD. Sci Rep. 2022 02 04; 12(1):1946.View Related Profiles.

Lazzari, Antonio
Wan, Emily
Moy, Marilyn

PMID: 35121763; PMCID: PMC8816927; DOI: 10.1038/s41598-022-05887-4;

Wan ES, Balte P, Schwartz JE, Bhatt SP, Cassano PA, Couper D, Daviglus ML, Dransfield MT, Gharib SA, Jacobs DR, Kalhan R, London SJ, Navas-Acien A, O'Connor GT, Sanders JL, Smith BM, White W, Yende S, Oelsner EC. Association Between Preserved Ratio Impaired Spirometry and Clinical Outcomes in US Adults. JAMA. 2021 12 14; 326(22):2287-2298.View Related Profiles.

Wan, Emily
O'Connor, George

PMID: 34905031; PMCID: PMC8672237; DOI: 10.1001/jama.2021.20939;

Bamonti PM, Boyle JT, Goodwin CL, Wan ES, Silberbogen AK, Finer EB, Moy ML. Predictors of Outpatient Pulmonary Rehabilitation Uptake, Adherence, Completion, and Treatment Response Among Male U.S. Veterans With Chronic Obstructive Pulmonary Disease. Arch Phys Med Rehabil. 2022 Jun; 103(6):1113-1121.e1.View Related Profiles.

Silberbogen, Amy
Wan, Emily
Moy, Marilyn

PMID: 34856155; PMCID: PMC9662698; DOI: 10.1016/j.apmr.2021.10.021;

Chu SH, Wan ES, Cho MH, Goryachev S, Gainer V, Linneman J, Scotty EJ, Hebbring SJ, Murphy S, Lasky-Su J, Weiss ST, Smoller JW, Karlson E. An independently validated, portable algorithm for the rapid identification of COPD patients using electronic health records. Sci Rep. 2021 10 07; 11(1):19959. PMID: 34620889; PMCID: PMC8497529; DOI: 10.1038/s41598-021-98719-w;

Wan ES, Hokanson JE, Regan EA, Young KA, Make BJ, DeMeo DL, Mason SE, San Jose Estepar R, Crapo JD, Silverman EK. Significant Spirometric Transitions and Preserved Ratio Impaired Spirometry Among Ever Smokers. Chest. 2022 Mar; 161(3):651-661. PMID: 34592319; PMCID: PMC8941606; DOI: 10.1016/j.chest.2021.09.021;

Lakshman Kumar P, Wilson AC, Rocco A, Cho MH, Wan E, Hobbs BD, Washko GR, Ortega VE, Christenson SA, Li X, Wells JM, Bhatt SP, DeMeo DL, Lutz SM, Rossiter H, Casaburi R, Rennard SI, Lomas DA, Labaki WW, Tal-Singer R, Bowler RP, Hersh CP, Tiwari HK, Dransfield M, Thalacker-Mercer A, Meyers DA, Silverman EK, McDonald MN. Genetic variation in genes regulating skeletal muscle regeneration and tissue remodelling associated with weight loss in chronic obstructive pulmonary disease. J Cachexia Sarcopenia Muscle. 2021 12; 12(6):1803-1817. PMID: 34523824; PMCID: PMC8718068; DOI: 10.1002/jcsm.12782;

Wade RC, Simmons JP, Boueiz A, Gregory A, Wan ES, Regan EA, Bhatt SP, Han MK, Bowler RP, Crapo JD, Silverman EK, Washko GR, Dransfield MT, Wells JM. Pulmonary Artery Enlargement Is Associated with Exacerbations and Mortality in Ever-Smokers with Preserved Ratio Impaired Spirometry. Am J Respir Crit Care Med. 2021 08 15; 204(4):481-485. PMID: 34014810; PMCID: PMC8480250; DOI: 10.1164/rccm.202103-0619LE;

Wan ES, Goldstein RL, Garshick E, DeMeo DL, Moy ML. Molecular markers of aging, exercise capacity, & physical activity in COPD. Respir Med. 2021 10; 187:106576.View Related Profiles.

Wan, Emily
Garshick, Eric
Moy, Marilyn

PMID: 34416615

Raphaely RA, Mongiardo MA, Goldstein RL, Robinson SA, Wan ES, Moy ML. Pain in Veterans with COPD: relationship with physical activity and exercise capacity. BMC Pulm Med. 2021 Jul 15; 21(1):238.View Related Profiles.

Wan, Emily
Moy, Marilyn
Robinson, Stephanie

PMID: 34266401; PMCID: PMC8280683; DOI: 10.1186/s12890-021-01601-8;

R Arnold N, S Wan E, Hersh CP, Schwartz A, Kinney G, Young K, Hokanson J, Regan EA, P Comellas A, Fortis S. Inhaled Medication Use in Smokers With Normal Spirometry. Respir Care. 2021 Apr; 66(4):652-660. PMID: 33563793; PMCID: PMC9993991; DOI: 10.4187/respcare.08016;

Fortis S, Wan ES, Kunisaki K, Eyck PT, Ballas ZK, Bowler RP, Crapo JD, Hokanson JE, Wendt C, Silverman EK, Comellas AP. Increased mortality associated with frequent exacerbations in COPD patients with mild-to-moderate lung function impairment, and smokers with normal spirometry. Respir Med X. 2021 Nov; 3. PMID: 35911870; PMCID: PMC9333066; DOI: 10.1016/j.yrmex.2020.100025;

Crowley CP, Wan ES, Salciccioli JD, Kim E. The Use of Mechanical Cardiopulmonary Resuscitation May Be Associated With Improved Outcomes Over Manual Cardiopulmonary Resuscitation During Inhospital Cardiac Arrests. Crit Care Explor. 2020 Nov; 2(11):e0261. PMID: 33225303; PMCID: PMC7671880; DOI: 10.1097/CCE.0000000000000261;

Robinson SA, Wan ES, Shimada SL, Richardson CR, Moy ML. Age and Attitudes Towards an Internet-Mediated, Pedometer-Based Physical Activity Intervention for Chronic Obstructive Pulmonary Disease: Secondary Analysis. JMIR Aging. 2020 Sep 09; 3(2):e19527.View Related Profiles.

Wan, Emily
Moy, Marilyn
Robinson, Stephanie
Shimada, Stephanie

PMID: 32902390; PMCID: PMC7511871; DOI: 10.2196/19527;

Fortis S, Comellas A, Kim V, Casaburi R, Hokanson JE, Crapo JD, Silverman EK, Wan ES. Low FVC/TLC in Preserved Ratio Impaired Spirometry (PRISm) is associated with features of and progression to obstructive lung disease. Sci Rep. 2020 03 20; 10(1):5169. PMID: 32198360; PMCID: PMC7083974; DOI: 10.1038/s41598-020-61932-0;

Wan ES, Kantorowski A, Polak M, Kadri R, Richardson CR, Gagnon DR, Garshick E, Moy ML. Long-term effects of web-based pedometer-mediated intervention on COPD exacerbations. Respir Med. 2020 02; 162:105878.View Related Profiles.

Gagnon, David
Wan, Emily
Garshick, Eric
Moy, Marilyn

PMID: 32056676; PMCID: PMC7269114; DOI: 10.1016/j.rmed.2020.105878;

Lowe KE, Regan EA, Anzueto A, Austin E, Austin JHM, Beaty TH, Benos PV, Benway CJ, Bhatt SP, Bleecker ER, Bodduluri S, Bon J, Boriek AM, Boueiz AR, Bowler RP, Budoff M, Casaburi R, Castaldi PJ, Charbonnier JP, Cho MH, Comellas A, Conrad D, Costa Davis C, Criner GJ, Curran-Everett D, Curtis JL, DeMeo DL, Diaz AA, Dransfield MT, Dy JG, Fawzy A, Fleming M, Flenaugh EL, Foreman MG, Fortis S, Gebrekristos H, Grant S, Grenier PA, Gu T, Gupta A, Han MK, Hanania NA, Hansel NN, Hayden LP, Hersh CP, Hobbs BD, Hoffman EA, Hogg JC, Hokanson JE, Hoth KF, Hsiao A, Humphries S, Jacobs K, Jacobson FL, Kazerooni EA, Kim V, Kim WJ, Kinney GL, Koegler H, Lutz SM, Lynch DA, MacIntye NR, Make BJ, Marchetti N, Martinez FJ, Maselli DJ, Mathews AM, McCormack MC, McDonald MN, McEvoy CE, Moll M, Molye SS, Murray S, Nath H, Newell JD, Occhipinti M, Paoletti M, Parekh T, Pistolesi M, Pratte KA, Putcha N, Ragland M, Reinhardt JM, Rennard SI, Rosiello RA, Ross JC, Rossiter HB, Ruczinski I, San Jose Estepar R, Sciurba FC, Sieren JC, Singh H, Soler X, Steiner RM, Strand MJ, Stringer WW, Tal-Singer R, Thomashow B, Vegas Sánchez-Ferrero G, Walsh JW, Wan ES, Washko GR, Michael Wells J, Wendt CH, Westney G, Wilson A, Wise RA, Yen A, Young K, Yun J, Silverman EK, Crapo JD. COPDGene® 2019: Redefining the Diagnosis of Chronic Obstructive Pulmonary Disease. Chronic Obstr Pulm Dis. 2019 Nov; 6(5):384-399. PMID: 31710793; PMCID: PMC7020846; DOI: 10.15326/jcopdf.6.5.2019.0149;

Young KA, Regan EA, Han MK, Lutz SM, Ragland M, Castaldi PJ, Washko GR, Cho MH, Strand M, Curran-Everett D, Beaty TH, Bowler RP, Wan ES, Lynch DA, Make BJ, Silverman EK, Crapo JD, Hokanson JE, Kinney GL. Subtypes of COPD Have Unique Distributions and Differential Risk of Mortality. Chronic Obstr Pulm Dis. 2019 Nov; 6(5):400-413. PMID: 31710795; PMCID: PMC7020845; DOI: 10.15326/jcopdf.6.5.2019.0150;

Wan ES, Goldstein RL, Fan VS, Nguyen HQ, Hart JE, Garshick E, Orr EH, DeVivo I, Moy ML. Telomere length in COPD: Relationships with physical activity, exercise capacity, and acute exacerbations. PLoS One. 2019; 14(10):e0223891.View Related Profiles.

Wan, Emily
Garshick, Eric
Moy, Marilyn

PMID: 31622416; PMCID: PMC6797105; DOI: 10.1371/journal.pone.0223891;

Maselli DJ, Bhatt SP, Anzueto A, Bowler RP, DeMeo DL, Diaz AA, Dransfield MT, Fawzy A, Foreman MG, Hanania NA, Hersh CP, Kim V, Kinney GL, Putcha N, Wan ES, Wells JM, Westney GE, Young KA, Silverman EK, Han MK, Make BJ. Clinical Epidemiology of COPD: Insights From 10 Years of the COPDGene Study. Chest. 2019 08; 156(2):228-238. PMID: 31154041; PMCID: PMC7198872; DOI: 10.1016/j.chest.2019.04.135;

Wan ES, Silverman EK. Reply to Marruchella: Preserved Ratio Impaired Spirometry and Interstitial Lung Abnormalities in Smokers. Am J Respir Crit Care Med. 2019 05 15; 199(10):1293-1294. PMID: 30802417; PMCID: PMC6519864; DOI: 10.1164/rccm.201901-0018LE;

Wan ES, Fortis S, Regan EA, Hokanson J, Han MK, Casaburi R, Make BJ, Crapo JD, DeMeo DL, Silverman EK. Longitudinal Phenotypes and Mortality in Preserved Ratio Impaired Spirometry in the COPDGene Study. Am J Respir Crit Care Med. 2018 12 01; 198(11):1397-1405. PMID: 29874098; PMCID: PMC6290948; DOI: 10.1164/rccm.201804-0663OC;

Kantorowski A, Wan ES, Homsy D, Kadri R, Richardson CR, Moy ML. Determinants and outcomes of change in physical activity in COPD. ERJ Open Res. 2018 Jul; 4(3).View Related Profiles.

Wan, Emily
Moy, Marilyn

PMID: 30083551; PMCID: PMC6073048; DOI: 10.1183/23120541.00054-2018;

Wan ES, Kantorowski A, Homsy D, Kadri R, Richardson CR, Mori D, Moy ML. Self-reported task-oriented physical activity: A comparison with objective daily step count in COPD. Respir Med. 2018 07; 140:63-70.View Related Profiles.

Mori, Deanna
Wan, Emily
Moy, Marilyn

PMID: 29957283

Wan ES. Examining genetic susceptibility in acute exacerbations of COPD. Thorax. 2018 06; 73(6):507-509. PMID: 29317548

Kim WJ, Yim JJ, Kim DK, Lee MG, Fuhlbrigge AL, Sliwinski P, Hawrylkiewicz I, Wan ES, Cho MH, Silverman EK. Severe COPD cases from Korea, Poland, and USA have substantial differences in respiratory symptoms and other respiratory illnesses. Int J Chron Obstruct Pulmon Dis. 2017; 12:3415-3423. PMID: 29238186; PMCID: PMC5716321; DOI: 10.2147/COPD.S145908;

Wan ES, Kantorowski A, Homsy D, Teylan M, Kadri R, Richardson CR, Gagnon DR, Garshick E, Moy ML. Promoting physical activity in COPD: Insights from a randomized trial of a web-based intervention and pedometer use. Respir Med. 2017 Sep; 130:102-110.View Related Profiles.

Gagnon, David
Wan, Emily
Garshick, Eric
Moy, Marilyn

PMID: 29206627; PMCID: PMC5718161; DOI: 10.1016/j.rmed.2017.07.057;

Wan ES, Li Y, Lao T, Qiu W, Jiang Z, Mancini JD, Owen CA, Clish C, DeMeo DL, Silverman EK, Zhou X. Metabolomic profiling in a Hedgehog Interacting Protein (Hhip) murine model of chronic obstructive pulmonary disease. Sci Rep. 2017 05 31; 7(1):2504. PMID: 28566717; PMCID: PMC5451406; DOI: 10.1038/s41598-017-02701-4;

Wan ES, DeMeo DL. Translating genomics into risk prediction. Thorax. 2017 07; 72(7):598-599. PMID: 28320931

Wain LV, Shrine N, Artigas MS, Erzurumluoglu AM, Noyvert B, Bossini-Castillo L, Obeidat M, Henry AP, Portelli MA, Hall RJ, Billington CK, Rimington TL, Fenech AG, John C, Blake T, Jackson VE, Allen RJ, Prins BP, Campbell A, Porteous DJ, Jarvelin MR, Wielscher M, James AL, Hui J, Wareham NJ, Zhao JH, Wilson JF, Joshi PK, Stubbe B, Rawal R, Schulz H, Imboden M, Probst-Hensch NM, Karrasch S, Gieger C, Deary IJ, Harris SE, Marten J, Rudan I, Enroth S, Gyllensten U, Kerr SM, Polasek O, Kähönen M, Surakka I, Vitart V, Hayward C, Lehtimäki T, Raitakari OT, Evans DM, Henderson AJ, Pennell CE, Wang CA, Sly PD, Wan ES, Busch R, Hobbs BD, Litonjua AA, Sparrow DW, Gulsvik A, Bakke PS, Crapo JD, Beaty TH, Hansel NN, Mathias RA, Ruczinski I, Barnes KC, Bossé Y, Joubert P, van den Berge M, Brandsma CA, Paré PD, Sin DD, Nickle DC, Hao K, Gottesman O, Dewey FE, Bruse SE, Carey DJ, Kirchner HL, Jonsson S, Thorleifsson G, Jonsdottir I, Gislason T, Stefansson K, Schurmann C, Nadkarni G, Bottinger EP, Loos RJ, Walters RG, Chen Z, Millwood IY, Vaucher J, Kurmi OP, Li L, Hansell AL, Brightling C, Zeggini E, Cho MH, Silverman EK, Sayers I, Trynka G, Morris AP, Strachan DP, Hall IP, Tobin MD. Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets. Nat Genet. 2017 Mar; 49(3):416-425.View Related Profiles.

Sparrow, David
Wan, Emily

PMID: 28166213; PMCID: PMC5326681; DOI: 10.1038/ng.3787;

Dransfield MT, Kunisaki KM, Strand MJ, Anzueto A, Bhatt SP, Bowler RP, Criner GJ, Curtis JL, Hanania NA, Nath H, Putcha N, Roark SE, Wan ES, Washko GR, Wells JM, Wendt CH, Make BJ. Acute Exacerbations and Lung Function Loss in Smokers with and without Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2017 02 01; 195(3):324-330. PMID: 27556408; PMCID: PMC5328181; DOI: 10.1164/rccm.201605-1014OC;

Kelly RS, Croteau-Chonka DC, Dahlin A, Mirzakhani H, Wu AC, Wan ES, McGeachie MJ, Qiu W, Sordillo JE, Al-Garawi A, Gray KJ, McElrath TF, Carey VJ, Clish CB, Litonjua AA, Weiss ST, Lasky-Su JA. Integration of metabolomic and transcriptomic networks in pregnant women reveals biological pathways and predictive signatures associated with preeclampsia. Metabolomics. 2017 Jan; 13(1). PMID: 28596717; PMCID: PMC5458629; DOI: 10.1007/s11306-016-1149-8;

Ishii T, Angata T, Wan ES, Cho MH, Motegi T, Gao C, Ohtsubo K, Kitazume S, Gemma A, ParÉ PD, Lomas DA, Silverman EK, Taniguchi N, Kida K. Influence of SIGLEC9 polymorphisms on COPD phenotypes including exacerbation frequency. Respirology. 2017 05; 22(4):684-690. PMID: 27878892

Kelly RS, Dahlin A, McGeachie MJ, Qiu W, Sordillo J, Wan ES, Wu AC, Lasky-Su J. Asthma Metabolomics and the Potential for Integrative Omics in Research and the Clinic. Chest. 2017 Feb; 151(2):262-277. PMID: 27776981; PMCID: PMC5310123; DOI: 10.1016/j.chest.2016.10.008;

Bhatt SP, Soler X, Wang X, Murray S, Anzueto AR, Beaty TH, Boriek AM, Casaburi R, Criner GJ, Diaz AA, Dransfield MT, Curran-Everett D, Galbán CJ, Hoffman EA, Hogg JC, Kazerooni EA, Kim V, Kinney GL, Lagstein A, Lynch DA, Make BJ, Martinez FJ, Ramsdell JW, Reddy R, Ross BD, Rossiter HB, Steiner RM, Strand MJ, van Beek EJ, Wan ES, Washko GR, Wells JM, Wendt CH, Wise RA, Silverman EK, Crapo JD, Bowler RP, Han MK. Association between Functional Small Airway Disease and FEV1 Decline in Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2016 07 15; 194(2):178-84. PMID: 26808615; PMCID: PMC5003216; DOI: 10.1164/rccm.201511-2219OC;

Kinney GL, Baker EH, Klein OL, Black-Shinn JL, Wan ES, Make B, Regan E, Bowler RP, Lutz SM, Young KA, Duca LM, Washko GR, Silverman EK, Crapo JD, Hokanson JE. Pulmonary Predictors of Incident Diabetes in Smokers. Chronic Obstr Pulm Dis. 2016; 3(4):739-747. PMID: 27795984; PMCID: PMC5084840; DOI: 10.15326/jcopdf.3.4.2016.0137;

Hardin M, Cho MH, McDonald ML, Wan E, Lomas DA, Coxson HO, MacNee W, Vestbo J, Yates JC, Agusti A, Calverley PM, Celli B, Crim C, Rennard S, Wouters E, Bakke P, Bhatt SP, Kim V, Ramsdell J, Regan EA, Make BJ, Hokanson JE, Crapo JD, Beaty TH, Hersh CP. A genome-wide analysis of the response to inhaled ß2-agonists in chronic obstructive pulmonary disease. Pharmacogenomics J. 2016 08; 16(4):326-35. PMID: 26503814; PMCID: PMC4848212; DOI: 10.1038/tpj.2015.65;

Wan ES, Qiu W, Carey VJ, Morrow J, Bacherman H, Foreman MG, Hokanson JE, Bowler RP, Crapo JD, DeMeo DL. Smoking-Associated Site-Specific Differential Methylation in Buccal Mucosa in the COPDGene Study. Am J Respir Cell Mol Biol. 2015 Aug; 53(2):246-54. PMID: 25517428; PMCID: PMC4566042; DOI: 10.1165/rcmb.2014-0103OC;

McGeachie MJ, Dahlin A, Qiu W, Croteau-Chonka DC, Savage J, Wu AC, Wan ES, Sordillo JE, Al-Garawi A, Martinez FD, Strunk RC, Lemanske RF, Liu AH, Raby BA, Weiss S, Clish CB, Lasky-Su JA. The metabolomics of asthma control: a promising link between genetics and disease. Immun Inflamm Dis. 2015 Sep; 3(3):224-38. PMID: 26421150; PMCID: PMC4578522; DOI: 10.1002/iid3.61;

Jaramillo JD, Wilson C, Stinson DS, Stinson DJ, Lynch DA, Bowler RP, Lutz S, Bon JM, Arnold B, McDonald ML, Washko GR, Wan ES, DeMeo DL, Foreman MG, Soler X, Lindsay SE, Lane NE, Genant HK, Silverman EK, Hokanson JE, Make BJ, Crapo JD, Regan EA. Reduced Bone Density and Vertebral Fractures in Smokers. Men and COPD Patients at Increased Risk. Ann Am Thorac Soc. 2015 May; 12(5):648-56. PMID: 25719895; PMCID: PMC4418341; DOI: 10.1513/AnnalsATS.201412-591OC;

Wan ES, Qiu W, Morrow J, Beaty TH, Hetmanski J, Make BJ, Lomas DA, Silverman EK, DeMeo DL. Genome-wide site-specific differential methylation in the blood of individuals with Klinefelter syndrome. Mol Reprod Dev. 2015 May; 82(5):377-86. PMID: 25988574; PMCID: PMC4439255; DOI: 10.1002/mrd.22483;

Qiu W, Wan E, Morrow J, Cho MH, Crapo JD, Silverman EK, DeMeo DL. The impact of genetic variation and cigarette smoke on DNA methylation in current and former smokers from the COPDGene study. Epigenetics. 2015; 10(11):1064-73. PMID: 26646902; PMCID: PMC4844199; DOI: 10.1080/15592294.2015.1106672;

Lee JH, McDonald ML, Cho MH, Wan ES, Castaldi PJ, Hunninghake GM, Marchetti N, Lynch DA, Crapo JD, Lomas DA, Coxson HO, Bakke PS, Silverman EK, Hersh CP. DNAH5 is associated with total lung capacity in chronic obstructive pulmonary disease. Respir Res. 2014 Aug 20; 15:97. PMID: 25134640; PMCID: PMC4169636; DOI: 10.1186/s12931-014-0097-y;

Lee JH, Cho MH, McDonald ML, Hersh CP, Castaldi PJ, Crapo JD, Wan ES, Dy JG, Chang Y, Regan EA, Hardin M, DeMeo DL, Silverman EK. Phenotypic and genetic heterogeneity among subjects with mild airflow obstruction in COPDGene. Respir Med. 2014 Oct; 108(10):1469-80. PMID: 25154699; PMCID: PMC4253548; DOI: 10.1016/j.rmed.2014.07.018;

Wan ES, Castaldi PJ, Cho MH, Hokanson JE, Regan EA, Make BJ, Beaty TH, Han MK, Curtis JL, Curran-Everett D, Lynch DA, DeMeo DL, Crapo JD, Silverman EK. Epidemiology, genetics, and subtyping of preserved ratio impaired spirometry (PRISm) in COPDGene. Respir Res. 2014 Aug 06; 15:89. PMID: 25096860; PMCID: PMC4256936; DOI: 10.1186/s12931-014-0089-y;

Kim SS, Yagihashi K, Stinson DS, Zach JA, McKenzie AS, Curran-Everett D, Wan ES, Silverman EK, Crapo JD, Lynch DA. Visual Assessment of CT Findings in Smokers With Nonobstructed Spirometric Abnormalities in The COPDGene® Study. Chronic Obstr Pulm Dis. 2014; 1(1):88-96. PMID: 25197723; PMCID: PMC4153727; DOI: 10.15326/jcopdf.1.1.2013.0001;

Martinez CH, Kim V, Chen Y, Kazerooni EA, Murray S, Criner GJ, Curtis JL, Regan EA, Wan E, Hersh CP, Silverman EK, Crapo JD, Martinez FJ, Han MK. The clinical impact of non-obstructive chronic bronchitis in current and former smokers. Respir Med. 2014 Mar; 108(3):491-9. PMID: 24280543; PMCID: PMC3943716; DOI: 10.1016/j.rmed.2013.11.003;

Kinney GL, Black-Shinn JL, Wan ES, Make B, Regan E, Lutz S, Soler X, Silverman EK, Crapo J, Hokanson JE. Pulmonary function reduction in diabetes with and without chronic obstructive pulmonary disease. Diabetes Care. 2014 Feb; 37(2):389-95. PMID: 24026562; PMCID: PMC3898761; DOI: 10.2337/dc13-1435;

Wan ES, Qiu W, Baccarelli A, Carey VJ, Bacherman H, Rennard SI, Agustí A, Anderson WH, Lomas DA, DeMeo DL. Systemic steroid exposure is associated with differential methylation in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2012 Dec 15; 186(12):1248-55. PMID: 23065012; PMCID: PMC3622442; DOI: 10.1164/rccm.201207-1280OC;

Hansel NN, Ruczinski I, Rafaels N, Sin DD, Daley D, Malinina A, Huang L, Sandford A, Murray T, Kim Y, Vergara C, Heckbert SR, Psaty BM, Li G, Elliott WM, Aminuddin F, Dupuis J, O'Connor GT, Doheny K, Scott AF, Boezen HM, Postma DS, Smolonska J, Zanen P, Mohamed Hoesein FA, de Koning HJ, Crystal RG, Tanaka T, Ferrucci L, Silverman E, Wan E, Vestbo J, Lomas DA, Connett J, Wise RA, Neptune ER, Mathias RA, Paré PD, Beaty TH, Barnes KC. Genome-wide study identifies two loci associated with lung function decline in mild to moderate COPD. Hum Genet. 2013 Jan; 132(1):79-90.View Related Profiles.

Wan, Emily
O'Connor, George
Dupuis, Josee

PMID: 22986903; PMCID: PMC3536920; DOI: 10.1007/s00439-012-1219-6;

Wan ES, Qiu W, Baccarelli A, Carey VJ, Bacherman H, Rennard SI, Agusti A, Anderson W, Lomas DA, Demeo DL. Cigarette smoking behaviors and time since quitting are associated with differential DNA methylation across the human genome. Hum Mol Genet. 2012 Jul 01; 21(13):3073-82. PMID: 22492999; PMCID: PMC3373248; DOI: 10.1093/hmg/dds135;

Hardin M, Zielinski J, Wan ES, Hersh CP, Castaldi PJ, Schwinder E, Hawrylkiewicz I, Sliwinski P, Cho MH, Silverman EK. CHRNA3/5, IREB2, and ADCY2 are associated with severe chronic obstructive pulmonary disease in Poland. Am J Respir Cell Mol Biol. 2012 Aug; 47(2):203-8. PMID: 22461431; PMCID: PMC3423462; DOI: 10.1165/rcmb.2012-0011OC;

Cho MH, Castaldi PJ, Wan ES, Siedlinski M, Hersh CP, Demeo DL, Himes BE, Sylvia JS, Klanderman BJ, Ziniti JP, Lange C, Litonjua AA, Sparrow D, Regan EA, Make BJ, Hokanson JE, Murray T, Hetmanski JB, Pillai SG, Kong X, Anderson WH, Tal-Singer R, Lomas DA, Coxson HO, Edwards LD, MacNee W, Vestbo J, Yates JC, Agusti A, Calverley PM, Celli B, Crim C, Rennard S, Wouters E, Bakke P, Gulsvik A, Crapo JD, Beaty TH, Silverman EK. A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13. Hum Mol Genet. 2012 Feb 15; 21(4):947-57.View Related Profiles.

Sparrow, David
Wan, Emily

PMID: 22080838; PMCID: PMC3298111; DOI: 10.1093/hmg/ddr524;

Wan ES, Hokanson JE, Murphy JR, Regan EA, Make BJ, Lynch DA, Crapo JD, Silverman EK. Clinical and radiographic predictors of GOLD-unclassified smokers in the COPDGene study. Am J Respir Crit Care Med. 2011 Jul 1; 184(1):57-63.View Related Profiles.

Wan, Emily
Murphy, John

PMID: 21493737; PMCID: PMC3172890; DOI: 10.1164/rccm.201101-0021OC;

Wan ES, DeMeo DL, Hersh CP, Shapiro SD, Rosiello RA, Sama SR, Fuhlbrigge AL, Foreman MG, Silverman EK. Clinical predictors of frequent exacerbations in subjects with severe chronic obstructive pulmonary disease (COPD). Respir Med. 2011 Apr; 105(4):588-94. PMID: 21145719; PMCID: PMC3046312; DOI: 10.1016/j.rmed.2010.11.015;

Wan ES, Cho MH, Boutaoui N, Klanderman BJ, Sylvia JS, Ziniti JP, Won S, Lange C, Pillai SG, Anderson WH, Kong X, Lomas DA, Bakke PS, Gulsvik A, Regan EA, Murphy JR, Make BJ, Crapo JD, Wouters EF, Celli BR, Silverman EK, DeMeo DL. Genome-wide association analysis of body mass in chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol. 2011 Aug; 45(2):304-10. PMID: 21037115; PMCID: PMC3266061; DOI: 10.1165/rcmb.2010-0294OC;

Wan ES, Pober BR, Washko GR, Raby BA, Silverman EK. Pulmonary function and emphysema in Williams-Beuren syndrome. Am J Med Genet A. 2010 Mar; 152A(3):653-6. PMID: 20186780; PMCID: PMC3397670; DOI: 10.1002/ajmg.a.33300;

Wan ES, Silverman EK. Genetics of COPD and emphysema. Chest. 2009 Sep; 136(3):859-866. PMID: 19736190

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 71 publications over 16 distinct years, with a maximum of 9 publications in 2021

Bar chart showing 71 publications over 16 distinct years, with a maximum of 9 publications in 2021

Year	Publications
2009	1
2010	3
2011	2
2012	4
2013	2
2014	4
2015	6
2016	5
2017	6
2018	4
2019	5
2020	5
2021	9
2022	6
2023	6
2024	3

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