Keywords
Last Name

Michael J Pencina, PhD

TitleAdjunct Professor
InstitutionBoston University School of Public Health
DepartmentBiostatistics
Address801 Massachusetts Ave Crosstown Center
Boston MA 02118
Phone(617) 638-5847
ORCID ORCID Icon0000-0001-5798-8855
 Research Expertise & Professional Interests
Dr. Michael Pencina is the Duke Clinical Research Institute Director of Biostatistics. He is Professor of Biostatistics & Bioinformatics at Duke and Adjunct Professor in the Department of Biostatistics at Boston University.

As the DCRI Director of Biostatistics, Dr. Pencina serves as a key institutional leader overseeing the strategic and operational direction of our biostatistics talent and resources at the DCRI. In this role, Dr. Pencina guides a strategic vision to meet the needs of DCRI investigators by developing necessary infrastructure while also partnering with the Biostatistics & Bioinformatics Department to assure that the DCRI’s objectives and services are well understood and supported.

Prior to joining the DCRI in 2013, Dr. Pencina served as an associate professor in the Department of Biostatistics at Boston University and as Director of Statistical Consulting at the Harvard Clinical Research Institute. He brings a wealth of experience in both clinical trials and observational analyses. He has worked on a number of large clinical trials as well as Framingham Heart Study projects. Dr. Pencina is an expert in cardiovascular disease risk prediction model development and assessment of performance. The novel metrics (net reclassification improvement and integrated discrimination improvement) for the assessment of usefulness of new biomarkers and genetic factors in risk prediction proposed by Dr. Pencina have been incorporated into the reporting guidelines. For the past year, Dr. Pencina has also served as the Associate Editor for Statistics in Medicine. He has authored more than 150 manuscripts that have been published in peer-reviewed journals. Dr. Pencina earned his PhD in Mathematics and Statistics at Boston University.

 Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Pagidipati NJ, Navar AM, Mulder H, Sniderman AD, Peterson ED, Pencina MJ. Comparison of Recommended Eligibility for Primary Prevention Statin Therapy Based on the US Preventive Services Task Force Recommendations vs the ACC/AHA Guidelines. JAMA. 2017 Apr 18; 317(15):1563-1567. PMID: 28418481.
    View in: PubMed
  2. Hoffmann U, Ferencik M, Udelson JE, Picard MH, Truong QA, Patel MR, Huang M, Pencina MJ, Mark DB, Heitner JF, Fordyce CB, Pellikka PA, Tardif JC, Budoff MJ, Nahhas G, Chow BJ, Kosinski AS, Lee KL, Douglas PS. Prognostic Value of Noninvasive Cardiovascular Testing in Patients with Stable Chest Pain: Insights from the PROMISE Trial. Circulation. 2017 Apr 07. PMID: 28389572.
    View in: PubMed
  3. Spratt SE, Pereira K, Granger BB, Batch BC, Phelan M, Pencina M, Miranda ML, Boulware E, Lucas JE, Nelson CL, Neely B, Goldstein BA, Barth P, Richesson RL, Riley IL, Corsino L, McPeek Hinz ER, Rusincovitch S, Green J, Barton AB. Assessing electronic health record phenotypes against gold-standard diagnostic criteria for diabetes mellitus. J Am Med Inform Assoc. 2017 Apr 01; 24(e1):e121-e128. PMID: 27616701.
    View in: PubMed
  4. Xian Y, O'Brien EC, Liang L, Xu H, Schwamm LH, Fonarow GC, Bhatt DL, Smith EE, Olson DM, Maisch L, Hannah D, Lindholm B, Lytle BL, Pencina MJ, Hernandez AF, Peterson ED. Association of Preceding Antithrombotic Treatment With Acute Ischemic Stroke Severity and In-Hospital Outcomes Among Patients With Atrial Fibrillation. JAMA. 2017 03 14; 317(10):1057-1067. PMID: 28291892.
    View in: PubMed
  5. Kopec G, Waligóra M, Tyrka A, Jonas K, Pencina MJ, Zdrojewski T, Moertl D, Stokwiszewski J, Zagozdzon P, Podolec P. Low-density lipoprotein cholesterol and survival in pulmonary arterial hypertension. Sci Rep. 2017 Feb 15; 7:41650. PMID: 28198422.
    View in: PubMed
  6. Fleming TR, DeMets DL, Roe MT, Wittes J, Calis KA, Vora AN, Meisel A, Bain RP, Konstam MA, Pencina MJ, Gordon DJ, Mahaffey KW, Hennekens CH, Neaton JD, Pearson GD, Andersson TL, Pfeffer MA, Ellenberg SS. Data monitoring committees: Promoting best practices to address emerging challenges. Clin Trials. 2017 Apr; 14(2):115-123. PMID: 28359194.
    View in: PubMed
  7. Fleming TR, DeMets DL, Roe MT, Wittes J, Calis KA, Vora AN, Meisel A, Bain RP, Konstam MA, Pencina MJ, Gordon DJ, Mahaffey KW, Hennekens CH, Neaton JD, Pearson GD, Andersson TL, Pfeffer MA, Ellenberg SS. Rejoinder. Clin Trials. 2017 Apr; 14(2):126-127. PMID: 28135837.
    View in: PubMed
  8. Li J, Feng Q, Fine JP, Pencina MJ, Van Calster B. Nonparametric estimation and inference for polytomous discrimination index. Stat Methods Med Res. 2017 Jan 01; 962280217692830. PMID: 28178877.
    View in: PubMed
  9. Stolker JM, Cohen DJ, Kennedy KF, Pencina MJ, Arnold SV, Kleiman NS, Spertus JA. Combining clinical and angiographic variables for estimating risk of target lesion revascularization after drug eluting stent placement. Cardiovasc Revasc Med. 2016 Dec 18. PMID: 28041858.
    View in: PubMed
  10. Robinson JG, Huijgen R, Ray K, Persons J, Kastelein JJ, Pencina MJ. Determining When to Add Nonstatin Therapy: A Quantitative Approach. J Am Coll Cardiol. 2016 Dec 06; 68(22):2412-2421. PMID: 27908345.
    View in: PubMed
  11. Wilson PW, Pencina MJ. Estimation of Risk for Initial Atherosclerotic Cardiovascular Disease Events: Taking Stock and Moving Forward. Circulation. 2016 Dec 06; 134(23):1792-1793. PMID: 27920071.
    View in: PubMed
  12. Pandey A, Golwala H, Xu H, DeVore AD, Matsouaka R, Pencina M, Kumbhani DJ, Hernandez AF, Bhatt DL, Heidenreich PA, Yancy CW, de Lemos JA, Fonarow GC. Association of 30-Day Readmission Metric for Heart Failure Under the Hospital Readmissions Reduction Program With Quality of Care and Outcomes. JACC Heart Fail. 2016 Dec; 4(12):935-946. PMID: 27908393.
    View in: PubMed
  13. Thomas LE, Pencina MJ. Do Not Over (P) Value Your Research Article. JAMA Cardiol. 2016 Dec 01; 1(9):1055. PMID: 27732688.
    View in: PubMed
  14. Goldstein BA, Navar AM, Pencina MJ. Risk Prediction With Electronic Health Records: The Importance of Model Validation and Clinical Context. JAMA Cardiol. 2016 Dec 01; 1(9):976-977. PMID: 27732706.
    View in: PubMed
  15. Goldstein BA, Bhavsar NA, Phelan M, Pencina MJ. Controlling for Informed Presence Bias Due to the Number of Health Encounters in an Electronic Health Record. Am J Epidemiol. 2016 Dec 01; 184(11):847-855. PMID: 27852603.
    View in: PubMed
  16. Navar AM, Peterson ED, Wojdyla D, Sanchez RJ, Sniderman AD, D'Agostino RB, Pencina MJ. Temporal Changes in the Association Between Modifiable Risk Factors and Coronary Heart Disease Incidence. JAMA. 2016 Nov 15; 316(19):2041-2043. PMID: 27838711.
    View in: PubMed
  17. Ngwa JS, Cabral HJ, Cheng DM, Pencina MJ, Gagnon DR, LaValley MP, Cupples LA. A comparison of time dependent Cox regression, pooled logistic regression and cross sectional pooling with simulations and an application to the Framingham Heart Study. BMC Med Res Methodol. 2016 Nov 03; 16(1):148. PMID: 27809784.
    View in: PubMed
  18. Navar AM, Pencina MJ, Peterson ED. Assessing Cardiovascular Risk to Guide Hypertension Diagnosis and Treatment. JAMA Cardiol. 2016 Nov 01; 1(8):864-871. PMID: 27604060.
    View in: PubMed
  19. Sniderman AD, Islam S, McQueen M, Pencina M, Furberg CD, Thanassoulis G, Yusuf S. Age and Cardiovascular Risk Attributable to Apolipoprotein B, Low-Density Lipoprotein Cholesterol or Non-High-Density Lipoprotein Cholesterol. J Am Heart Assoc. 2016 Oct 13; 5(10). PMID: 27737874.
    View in: PubMed
  20. Crowley AL, Yow E, Barnhart HX, Daubert MA, Bigelow R, Sullivan DC, Pencina M, Douglas PS. Critical Review of Current Approaches for Echocardiographic Reproducibility and Reliability Assessment in Clinical Research. J Am Soc Echocardiogr. 2016 Dec; 29(12):1144-1154.e7. PMID: 27720558.
    View in: PubMed
  21. Pencina MJ, Fine JP, D'Agostino RB. Discrimination slope and integrated discrimination improvement - properties, relationships and impact of calibration. Stat Med. 2016 Oct 03. PMID: 27699818.
    View in: PubMed
  22. O'Brien EC, Xian Y, Xu H, Wu J, Saver JL, Smith EE, Schwamm LH, Peterson ED, Reeves MJ, Bhatt DL, Maisch L, Hannah D, Lindholm B, Olson D, Prvu Bettger J, Pencina M, Hernandez AF, Fonarow GC. Hospital Variation in Home-Time After Acute Ischemic Stroke: Insights From the PROSPER Study (Patient-Centered Research Into Outcomes Stroke Patients Prefer and Effectiveness Research). Stroke. 2016 Oct; 47(10):2627-33. PMID: 27625383.
    View in: PubMed
  23. Lee JC, Zdrojewski T, Pencina MJ, Wyszomirski A, Lachacz M, Opolski G, Bandosz P, Rutkowski M, Gaciong Z, Wyrzykowski B, Navar AM. Population Effect of Differences in Cholesterol Guidelines in Eastern Europe and the United States. JAMA Cardiol. 2016 Sep 01; 1(6):700-7. PMID: 27434662.
    View in: PubMed
  24. Hornik CP, Benjamin DK, Smith PB, Pencina MJ, Tremoulet AH, Capparelli EV, Ericson JE, Clark RH, Cohen-Wolkowiez M. Electronic Health Records and Pharmacokinetic Modeling to Assess the Relationship between Ampicillin Exposure and Seizure Risk in Neonates. J Pediatr. 2016 Nov; 178:125-129.e1. PMID: 27522443.
    View in: PubMed
  25. Navar AM, Pencina MJ, Peterson ED. Open Access Platforms for Sharing Clinical Trial Data--Reply. JAMA. 2016 Aug 9; 316(6):666-7. PMID: 27532930.
    View in: PubMed
  26. Pencina MJ, Steyerberg EW, D'Agostino RB. Net reclassification index at event rate: properties and relationships. Stat Med. 2016 Jul 18. PMID: 27426413.
    View in: PubMed
  27. Chrusciel P, Sahebkar A, Rembek-Wieliczko M, Serban MC, Ursoniu S, Mikhailidis DP, Jones SR, Mosteoru S, Blaha MJ, Martin SS, Rysz J, Toth PP, Lip GY, Pencina MJ, Ray KK, Banach M. Impact of statin therapy on plasma adiponectin concentrations: A systematic review and meta-analysis of 43 randomized controlled trial arms. Atherosclerosis. 2016 Oct; 253:194-208. PMID: 27498397.
    View in: PubMed
  28. Sniderman AD, Thanassoulis G, Williams K, Pencina M. Risk of Premature Cardiovascular Disease vs the Number of Premature Cardiovascular Events. JAMA Cardiol. 2016 Jul 01; 1(4):492-4. PMID: 27438330.
    View in: PubMed
  29. Goldstein BA, Pencina MJ, Montez-Rath ME, Winkelmayer WC. Predicting mortality over different time horizons: which data elements are needed? J Am Med Inform Assoc. 2017 Jan; 24(1):176-181. PMID: 27357832.
    View in: PubMed
  30. Banach M, Serban MC, Sahebkar A, García-García HM, Mikhailidis DP, Martin SS, Brie D, Rysz J, Toth PP, Jones SR, Hasan RK, Mosteoru S, Al Rifai M, Pencina MJ, Serruys PW. Comparison of clinical outcomes between bioresorbable vascular stents versus conventional drug-eluting and metallic stents: a systematic review and meta-analysis. EuroIntervention. 2016 Jun 12; 12(2):e175-89. PMID: 27290677.
    View in: PubMed
  31. Mentz RJ, Newby LK, Neely B, Lucas JE, Pokorney SD, Rao MP, Jackson LR, Grau-Sepulveda MV, Smerek MM, Barth P, Nelson CL, Pencina MJ, Shah BR. Assessment of Administrative Data to Identify Acute Myocardial Infarction in Electronic Health Records. J Am Coll Cardiol. 2016 May 24; 67(20):2441-2. PMID: 27199066.
    View in: PubMed
  32. Goldstein BA, Navar AM, Pencina MJ, Ioannidis JP. Opportunities and challenges in developing risk prediction models with electronic health records data: a systematic review. J Am Med Inform Assoc. 2017 Jan; 24(1):198-208. PMID: 27189013.
    View in: PubMed
  33. Clement ME, Park LP, Navar AM, Okeke NL, Pencina MJ, Douglas PS, Naggie S. Statin Utilization and Recommendations Among HIV- and HCV-infected Veterans: A Cohort Study. Clin Infect Dis. 2016 Aug 01; 63(3):407-13. PMID: 27143663.
    View in: PubMed
  34. McGuire DK, Van de Werf F, Armstrong PW, Standl E, Koglin J, Green JB, Bethel MA, Cornel JH, Lopes RD, Halvorsen S, Ambrosio G, Buse JB, Josse RG, Lachin JM, Pencina MJ, Garg J, Lokhnygina Y, Holman RR, Peterson ED. Association Between Sitagliptin Use and Heart Failure Hospitalization and Related Outcomes in Type 2 Diabetes Mellitus: Secondary Analysis of a Randomized Clinical Trial. JAMA Cardiol. 2016 May 01; 1(2):126-35. PMID: 27437883.
    View in: PubMed
  35. Pagidipati NJ, Pencina M, Sniderman AD. The Enigma of Glucose and Lipid Metabolism. JAMA Cardiol. 2016 May 01; 1(2):145-6. PMID: 27437884.
    View in: PubMed
  36. Pencina MJ, Peterson ED. Moving From Clinical Trials to Precision Medicine: The Role for Predictive Modeling. JAMA. 2016 Apr 26; 315(16):1713-4. PMID: 27115375.
    View in: PubMed
  37. Fox ER, Samdarshi TE, Musani SK, Pencina MJ, Sung JH, Bertoni AG, Xanthakis V, Balfour PC, Shreenivas SS, Covington C, Liebson PR, Sarpong DF, Butler KR, Mosley TH, Rosamond WD, Folsom AR, Herrington DM, Vasan RS, Taylor HA. Development and Validation of Risk Prediction Models for Cardiovascular Events in Black Adults: The Jackson Heart Study Cohort. JAMA Cardiol. 2016 Apr 01; 1(1):15-25. PMID: 27437649.
    View in: PubMed
  38. Thanassoulis G, Williams K, Altobelli KK, Pencina MJ, Cannon CP, Sniderman AD. Individualized Statin Benefit for Determining Statin Eligibility in the Primary Prevention of Cardiovascular Disease. Circulation. 2016 Apr 19; 133(16):1574-81. PMID: 26945047.
    View in: PubMed
  39. Navar AM, Pencina MJ, Rymer JA, Louzao DM, Peterson ED. Use of Open Access Platforms for Clinical Trial Data. JAMA. 2016 Mar 22-29; 315(12):1283-4. PMID: 27002452.
    View in: PubMed
  40. Banovic M, Iung B, Bartunek J, Asanin M, Beleslin B, Biocina B, Casselman F, da Costa M, Deja M, Gasparovic H, Kala P, Labrousse L, Loncar Z, Marinkovic J, Nedeljkovic I, Nedeljkovic M, Nemec P, Nikolic SD, Pencina M, Penicka M, Ristic A, Sharif F, Van Camp G, Vanderheyden M, Wojakowski W, Putnik S. Rationale and design of the Aortic Valve replAcemenT versus conservative treatment in Asymptomatic seveRe aortic stenosis (AVATAR trial): A randomized multicenter controlled event-driven trial. Am Heart J. 2016 Apr; 174:147-53. PMID: 26995381.
    View in: PubMed
  41. Van Calster B, Nieboer D, Vergouwe Y, De Cock B, Pencina MJ, Steyerberg EW. A calibration hierarchy for risk models was defined: from utopia to empirical data. J Clin Epidemiol. 2016 Jun; 74:167-76. PMID: 26772608.
    View in: PubMed
  42. Zdrojewski T, Solnica B, Cybulska B, Bandosz P, Rutkowski M, Stokwiszewski J, Gaciong Z, Banach M, Wojtyniak B, Pencina M, Wyrzykowski B. Prevalence of lipid abnormalities in Poland. The NATPOL 2011 survey. Kardiol Pol. 2016; 74(3):213-23. PMID: 27004543.
    View in: PubMed
  43. Holman RR, Bethel MA, George J, Sourij H, Doran Z, Keenan J, Khurmi NS, Mentz RJ, Oulhaj A, Buse JB, Chan JC, Iqbal N, Kundu S, Maggioni AP, Marso SP, Öhman P, Pencina MJ, Poulter N, Porter LE, Ramachandran A, Zinman B, Hernandez AF. Rationale and design of the EXenatide Study of Cardiovascular Event Lowering (EXSCEL) trial. Am Heart J. 2016 Apr; 174:103-10. PMID: 26995376.
    View in: PubMed
  44. Sahebkar A, Serban MC, Mikhailidis DP, Toth PP, Muntner P, Ursoniu S, Mosterou S, Glasser S, Martin SS, Jones SR, Rizzo M, Rysz J, Sniderman AD, Pencina MJ, Banach M. Head-to-head comparison of statins versus fibrates in reducing plasma fibrinogen concentrations: A systematic review and meta-analysis. Pharmacol Res. 2016 Jan; 103:236-52. PMID: 26657419.
    View in: PubMed
  45. Shelton RC, Pencina MJ, Barrentine LW, Ruiz JA, Fava M, Zajecka JM, Papakostas GI. Association of obesity and inflammatory marker levels on treatment outcome: results from a double-blind, randomized study of adjunctive L-methylfolate calcium in patients with MDD who are inadequate responders to SSRIs. J Clin Psychiatry. 2015 Dec; 76(12):1635-41. PMID: 26613389.
    View in: PubMed
  46. Pencina MJ, Louzao DM, McCourt BJ, Adams MR, Tayyabkhan RH, Ronco P, Peterson ED. Supporting open access to clinical trial data for researchers: The Duke Clinical Research Institute-Bristol-Myers Squibb Supporting Open Access to Researchers Initiative. Am Heart J. 2016 Feb; 172:64-9. PMID: 26856217.
    View in: PubMed
  47. Sniderman AD, D'Agostino RB, Pencina MJ. Risk Prediction for Individuals--Reply. JAMA. 2015 Nov 3; 314(17):1875-6. PMID: 26529170.
    View in: PubMed
  48. Wechsler ME, Yawn BP, Fuhlbrigge AL, Pace WD, Pencina MJ, Doros G, Kazani S, Raby BA, Lanzillotti J, Madison S, Israel E. Anticholinergic vs Long-Acting ß-Agonist in Combination With Inhaled Corticosteroids in Black Adults With Asthma: The BELT Randomized Clinical Trial. JAMA. 2015 Oct 27; 314(16):1720-30. PMID: 26505596.
    View in: PubMed
  49. Navar-Boggan AM, Peterson ED, D'Agostino RB, Neely B, Sniderman AD, Pencina MJ. Response to Letter Regarding Article, "Hyperlipidemia in Early Adulthood Increases Long-Term Risk of Coronary Heart Disease". Circulation. 2015 Oct 20; 132(16):e203. PMID: 26481569.
    View in: PubMed
  50. O'Brien EC, Simon DN, Thomas LE, Hylek EM, Gersh BJ, Ansell JE, Kowey PR, Mahaffey KW, Chang P, Fonarow GC, Pencina MJ, Piccini JP, Peterson ED. The ORBIT bleeding score: a simple bedside score to assess bleeding risk in atrial fibrillation. Eur Heart J. 2015 Dec 7; 36(46):3258-64. PMID: 26424865.
    View in: PubMed
  51. Wu LT, Ghitza UE, Batch BC, Pencina MJ, Rojas LF, Goldstein BA, Schibler T, Dunham AA, Rusincovitch S, Brady KT. Substance use and mental diagnoses among adults with and without type 2 diabetes: Results from electronic health records data. Drug Alcohol Depend. 2015 Nov 1; 156:162-9. PMID: 26392231.
    View in: PubMed
  52. Pencina MJ, D'Agostino RB. Evaluating Discrimination of Risk Prediction Models: The C Statistic. JAMA. 2015 Sep 8; 314(10):1063-4. PMID: 26348755.
    View in: PubMed
  53. O'Brien EC, Greiner MA, Xian Y, Fonarow GC, Olson DM, Schwamm LH, Bhatt DL, Smith EE, Maisch L, Hannah D, Lindholm B, Peterson ED, Pencina MJ, Hernandez AF. Clinical Effectiveness of Statin Therapy After Ischemic Stroke: Primary Results From the Statin Therapeutic Area of the Patient-Centered Research Into Outcomes Stroke Patients Prefer and Effectiveness Research (PROSPER) Study. Circulation. 2015 Oct 13; 132(15):1404-13. PMID: 26246175.
    View in: PubMed
  54. Xian Y, Wu J, O'Brien EC, Fonarow GC, Olson DM, Schwamm LH, Bhatt DL, Smith EE, Suter RE, Hannah D, Lindholm B, Maisch L, Greiner MA, Lytle BL, Pencina MJ, Peterson ED, Hernandez AF. Real world effectiveness of warfarin among ischemic stroke patients with atrial fibrillation: observational analysis from Patient-Centered Research into Outcomes Stroke Patients Prefer and Effectiveness Research (PROSPER) study. BMJ. 2015; 351:h3786. PMID: 26232340.
    View in: PubMed
  55. Navar AM, Pencina M. ACP Journal Club. In adults without CV disease, most prediction scores overestimated risk for atherosclerotic CV events. Ann Intern Med. 2015 Jul 21; 163(2):JC13. PMID: 26192581.
    View in: PubMed
  56. Sinning JM, Wollert KC, Sedaghat A, Widera C, Radermacher MC, Descoups C, Hammerstingl C, Weber M, Stundl A, Ghanem A, Widder J, Vasa-Nicotera M, Mellert F, Schiller W, Bauersachs J, Zur B, Holdenrieder S, Welz A, Grube E, Pencina MJ, Nickenig G, Werner N, Kempf T. Risk scores and biomarkers for the prediction of 1-year outcome after transcatheter aortic valve replacement. Am Heart J. 2015 Oct; 170(4):821-9. PMID: 26386807.
    View in: PubMed
  57. Goff DC, D'Agostino RB, Pencina M, Lloyd-Jones DM. Calibration and Discrimination Among Multiple Cardiovascular Risk Scores in a Modern Multiethnic Cohort. Ann Intern Med. 2015 Jul 7; 163(1):68. PMID: 26148286.
    View in: PubMed
  58. Sniderman AD, D'Agostino RB, Pencina MJ. The Role of Physicians in the Era of Predictive Analytics. JAMA. 2015 Jul 7; 314(1):25-6. PMID: 26151261.
    View in: PubMed
  59. Ko MJ, Kim YJ, Park CM, Lee SM, Lee WJ, Pencina MJ, Navar-Boggan AM, Park DW. Applicability and potential clinical effects of 2013 cholesterol guidelines on major cardiovascular events. Am Heart J. 2015 Sep; 170(3):598-605.e7. PMID: 26385045.
    View in: PubMed
  60. Fine JP, Pencina M. On the quantitative assessment of predictive biomarkers. J Natl Cancer Inst. 2015 Aug; 107(8). PMID: 26109107.
    View in: PubMed
  61. Green JB, Bethel MA, Armstrong PW, Buse JB, Engel SS, Garg J, Josse R, Kaufman KD, Koglin J, Korn S, Lachin JM, McGuire DK, Pencina MJ, Standl E, Stein PP, Suryawanshi S, Van de Werf F, Peterson ED, Holman RR. Effect of Sitagliptin on Cardiovascular Outcomes in Type 2 Diabetes. N Engl J Med. 2015 Jul 16; 373(3):232-42. PMID: 26052984.
    View in: PubMed
  62. Jansen H, Loley C, Lieb W, Pencina MJ, Nelson CP, Kathiresan S, Peloso GM, Voight BF, Reilly MP, Assimes TL, Boerwinkle E, Hengstenberg C, Laaksonen R, McPherson R, Roberts R, Thorsteinsdottir U, Peters A, Gieger C, Rawal R, Thompson JR, König IR. Genetic variants primarily associated with type 2 diabetes are related to coronary artery disease risk. Atherosclerosis. 2015 Aug; 241(2):419-26. PMID: 26074316.
    View in: PubMed
  63. Sniderman AD, Pencina M, Thanassoulis G. Limitations in the conventional assessment of the incremental value of predictors of cardiovascular risk. Curr Opin Lipidol. 2015 Jun; 26(3):210-4. PMID: 25887681.
    View in: PubMed
  64. Xian Y, O'Brien EC, Fonarow GC, Olson DM, Schwamm LH, Hannah D, Lindholm B, Maisch L, Lytle BL, Greiner MA, Wu J, Peterson ED, Pencina MJ, Hernandez AF. Patient-Centered Research into Outcomes Stroke Patients Prefer and Effectiveness Research: Implementing the patient-driven research paradigm to aid decision making in stroke care. Am Heart J. 2015 Jul; 170(1):36-45, 45.e1-11. PMID: 26093862.
    View in: PubMed
  65. Rybin D, Doros G, Pencina MJ, Fava M. Placebo non-response measure in sequential parallel comparison design studies. Stat Med. 2015 Jul 10; 34(15):2281-93. PMID: 25865181.
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  66. Min JK, Dunning A, Gransar H, Achenbach S, Lin FY, Al-Mallah M, Budoff MJ, Callister TQ, Chang HJ, Cademartiri F, Maffei E, Chinnaiyan K, Chow BJ, D'Agostino R, DeLago A, Friedman J, Hadamitzky M, Hausleiter J, Hayes SW, Kaufmann P, Raff GL, Shaw LJ, Thomson L, Villines T, Cury RC, Feuchtner G, Kim YJ, Leipsic J, Marques H, Berman DS, Pencina M. Medical history for prognostic risk assessment and diagnosis of stable patients with suspected coronary artery disease. Am J Med. 2015 Aug; 128(8):871-8. PMID: 25865923.
    View in: PubMed
  67. Bandosz P, O'Flaherty M, Rutkowski M, Kypridemos C, Guzman-Castillo M, Gillespie DO, Solnica B, Pencina MJ, Wyrzykowski B, Capewell S, Zdrojewski T. A victory for statins or a defeat for diet policies? Cholesterol falls in Poland in the past decade: A modeling study. Int J Cardiol. 2015 Apr 15; 185:313-9. PMID: 25828672.
    View in: PubMed
  68. Navar-Boggan AM, Peterson ED, D'Agostino RB, Pencina MJ, Sniderman AD. Using age- and sex-specific risk thresholds to guide statin therapy: one size may not fit all. J Am Coll Cardiol. 2015 Apr 28; 65(16):1633-9. PMID: 25743624.
    View in: PubMed
  69. Mühlenbruch K, Kuxhaus O, Pencina MJ, Boeing H, Liero H, Schulze MB. A confidence ellipse for the Net Reclassification Improvement. Eur J Epidemiol. 2015 Apr; 30(4):299-304. PMID: 25724473.
    View in: PubMed
  70. Pencina MJ, D'Agostino RB, Zdrojewski T, Williams K, Thanassoulis G, Furberg CD, Peterson ED, Vasan RS, Sniderman AD. Apolipoprotein B improves risk assessment of future coronary heart disease in the Framingham Heart Study beyond LDL-C and non-HDL-C. Eur J Prev Cardiol. 2015 Oct; 22(10):1321-7. PMID: 25633587.
    View in: PubMed
  71. Dallmeier D, Pencina MJ, Rajman I, Koenig W, Rothenbacher D, Brenner H. Serial measurements of N-terminal pro-brain natriuretic peptide in patients with coronary heart disease. PLoS One. 2015; 10(1):e0117143. PMID: 25629613.
    View in: PubMed
  72. Navar-Boggan AM, Peterson ED, D'Agostino RB, Neely B, Sniderman AD, Pencina MJ. Hyperlipidemia in early adulthood increases long-term risk of coronary heart disease. Circulation. 2015 Feb 3; 131(5):451-8. PMID: 25623155.
    View in: PubMed
  73. Shao F, Li J, Fine J, Wong WK, Pencina M. Inference for reclassification statistics under nested and non-nested models for biomarker evaluation. Biomarkers. 2015; 20(4):240-52. PMID: 26301882.
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  74. Abraham TM, Pencina KM, Pencina MJ, Fox CS. Trends in diabetes incidence: the Framingham Heart Study. Diabetes Care. 2015 Mar; 38(3):482-7. PMID: 25552418.
    View in: PubMed
  75. Pencina MJ, Neely B, Steyerberg EW. RE: net risk reclassification P Values: valid or misleading? J Natl Cancer Inst. 2015 Jan; 107(1):355. PMID: 25432411.
    View in: PubMed
  76. Magnani JW, Zhu L, Lopez F, Pencina MJ, Agarwal SK, Soliman EZ, Benjamin EJ, Alonso A. P-wave indices and atrial fibrillation: cross-cohort assessments from the Framingham Heart Study (FHS) and Atherosclerosis Risk in Communities (ARIC) study. Am Heart J. 2015 Jan; 169(1):53-61.e1. PMID: 25497248.
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  233. Wolongevicz DM, Zhu L, Pencina MJ, Kimokoti RW, Newby PK, D'Agostino RB, Millen BE. Diet quality and obesity in women: the Framingham Nutrition Studies. Br J Nutr. 2010 Apr; 103(8):1223-9. PMID: 19930766.
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  234. Lindsey JB, Marso SP, Pencina M, Stolker JM, Kennedy KF, Rihal C, Barsness G, Piana RN, Goldberg SL, Cutlip DE, Kleiman NS, Cohen DJ. Prognostic impact of periprocedural bleeding and myocardial infarction after percutaneous coronary intervention in unselected patients: results from the EVENT (evaluation of drug-eluting stents and ischemic events) registry. JACC Cardiovasc Interv. 2009 Nov; 2(11):1074-82. PMID: 19926047.
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  236. Preis SR, Pencina MJ, Hwang SJ, D'Agostino RB, Savage PJ, Levy D, Fox CS. Trends in cardiovascular disease risk factors in individuals with and without diabetes mellitus in the Framingham Heart Study. Circulation. 2009 Jul 21; 120(3):212-20. PMID: 19581493.
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  237. Melander O, Newton-Cheh C, Almgren P, Hedblad B, Berglund G, Engström G, Persson M, Smith JG, Magnusson M, Christensson A, Struck J, Morgenthaler NG, Bergmann A, Pencina MJ, Wang TJ. Novel and conventional biomarkers for prediction of incident cardiovascular events in the community. JAMA. 2009 Jul 1; 302(1):49-57. PMID: 19567439.
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  238. Lieb W, Xanthakis V, Sullivan LM, Aragam J, Pencina MJ, Larson MG, Benjamin EJ, Vasan RS. Longitudinal tracking of left ventricular mass over the adult life course: clinical correlates of short- and long-term change in the framingham offspring study. Circulation. 2009 Jun 23; 119(24):3085-92. PMID: 19506113.
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  240. Joseph J, Pencina MJ, Wang TJ, Hayes L, Tofler GH, Jacques P, Selhub J, Levy D, D'Agostino RB, Benjamin EJ, Vasan RS. Cross-sectional relations of multiple biomarkers representing distinct biological pathways to plasma markers of collagen metabolism in the community. J Hypertens. 2009 Jun; 27(6):1317-24. PMID: 19357531.
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  241. Novack V, Tsyvine D, Cohen DJ, Pencina M, Dubin J, Dehghani H, Kleiman NS, Cutlip DE. Multivessel drug-eluting stenting and impact of diabetes mellitus--a report from the EVENT registry. Catheter Cardiovasc Interv. 2009 Jun 1; 73(7):874-80. PMID: 19180665.
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  242. Matthan NR, Pencina M, LaRocque JM, Jacques PF, D'Agostino RB, Schaefer EJ, Lichtenstein AH. Alterations in cholesterol absorption/synthesis markers characterize Framingham offspring study participants with CHD. J Lipid Res. 2009 Sep; 50(9):1927-35. PMID: 19436064.
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  244. Schnabel RB, Sullivan LM, Levy D, Pencina MJ, Massaro JM, D'Agostino RB, Newton-Cheh C, Yamamoto JF, Magnani JW, Tadros TM, Kannel WB, Wang TJ, Ellinor PT, Wolf PA, Vasan RS, Benjamin EJ. Development of a risk score for atrial fibrillation (Framingham Heart Study): a community-based cohort study. Lancet. 2009 Feb 28; 373(9665):739-45. PMID: 19249635.
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  246. Latif F, Kleiman NS, Cohen DJ, Pencina MJ, Yen CH, Cutlip DE, Moliterno DJ, Nassif D, Lopez JJ, Saucedo JF. In-hospital and 1-year outcomes among percutaneous coronary intervention patients with chronic kidney disease in the era of drug-eluting stents: a report from the EVENT (Evaluation of Drug Eluting Stents and Ischemic Events) registry. JACC Cardiovasc Interv. 2009 Jan; 2(1):37-45. PMID: 19463396.
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  247. Dietrich M, Jacques PF, Pencina MJ, Lanier K, Keyes MJ, Kaur G, Wolf PA, D'Agostino RB, Vasan RS. Vitamin E supplement use and the incidence of cardiovascular disease and all-cause mortality in the Framingham Heart Study: Does the underlying health status play a role? Atherosclerosis. 2009 Aug; 205(2):549-53. PMID: 19195657.
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  248. Jacobs K, Johnson P, Dennerlein J, Peterson D, Kaufman J, Gold J, Williams S, Richmond N, Karban S, Firn E, Ansong E, Hudak S, Tung K, Hall V, Pencina K, Pencina M. University students' notebook computer use. Appl Ergon. 2009 May; 40(3):404-9. PMID: 19101663.
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  249. Wilson PW, Pencina M, Jacques P, Selhub J, D'Agostino R, O'Donnell CJ. C-reactive protein and reclassification of cardiovascular risk in the Framingham Heart Study. Circ Cardiovasc Qual Outcomes. 2008 Nov; 1(2):92-7. PMID: 20031795.
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  250. Lago RM, Pencina MJ, Wang TJ, Lanier KJ, D'Agostino RB, Kannel WB, Vasan RS. Interindividual variation in serum sodium and longitudinal blood pressure tracking in the Framingham Heart Study. J Hypertens. 2008 Nov; 26(11):2121-5. PMID: 18854750.
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  251. Velagaleti RS, Pencina MJ, Murabito JM, Wang TJ, Parikh NI, D'Agostino RB, Levy D, Kannel WB, Vasan RS. Long-term trends in the incidence of heart failure after myocardial infarction. Circulation. 2008 Nov 11; 118(20):2057-62. PMID: 18955667.
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  252. Diaz T, Pencina MJ, Benjamin EJ, Aragam J, Fuller DL, Pencina KM, Levy D, Vasan RS. Prevalence, clinical correlates, and prognosis of discrete upper septal thickening on echocardiography: the Framingham Heart Study. Echocardiography. 2009 Mar; 26(3):247-53. PMID: 19175779.
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  253. Lieb W, Pencina MJ, Lanier KJ, Tofler GH, Levy D, Fox CS, Wang TJ, D'Agostino RB, Vasan RS. Association of parental obesity with concentrations of select systemic biomarkers in nonobese offspring: the Framingham Heart Study. Diabetes. 2009 Jan; 58(1):134-7. PMID: 18931036.
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  254. Fernandez AB, Keyes MJ, Pencina M, D'Agostino R, O'Donnell CJ, Thompson PD. Relation of corneal arcus to cardiovascular disease (from the Framingham Heart Study data set). Am J Cardiol. 2009 Jan 1; 103(1):64-6. PMID: 19101231.
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  255. Pencina MJ, Millen BE, Hayes LJ, D'Agostino RB. Performance of a method for identifying the unique dietary patterns of adult women and men: the Framingham nutrition studies. J Am Diet Assoc. 2008 Sep; 108(9):1453-60. PMID: 18755317.
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  256. McCarthy EP, Pencina MJ, Kelly-Hayes M, Evans JC, Oberacker EJ, D'Agostino RB, Burns RB, Murabito JM. Advance care planning and health care preferences of community-dwelling elders: the Framingham Heart Study. J Gerontol A Biol Sci Med Sci. 2008 Sep; 63(9):951-9. PMID: 18840800.
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  258. Jeremias A, Kleiman NS, Nassif D, Hsieh WH, Pencina M, Maresh K, Parikh M, Cutlip DE, Waksman R, Goldberg S, Berger PB, Cohen DJ. Prevalence and prognostic significance of preprocedural cardiac troponin elevation among patients with stable coronary artery disease undergoing percutaneous coronary intervention: results from the evaluation of drug eluting stents and ischemic events registry. Circulation. 2008 Aug 5; 118(6):632-8. PMID: 18645057.
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  259. Lieb W, Pencina MJ, Wang TJ, Larson MG, Lanier KJ, Benjamin EJ, Levy D, Tofler GH, Meigs JB, Newton-Cheh C, Vasan RS. Association of parental hypertension with concentrations of select biomarkers in nonhypertensive offspring. Hypertension. 2008 Aug; 52(2):381-6. PMID: 18574071.
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  260. Pencina MJ, D'Agostino RB. Evaluation of the Framingham risk score in the European Prospective Investigation of Cancer-Norfolk cohort--invited commentary. Arch Intern Med. 2008 Jun 9; 168(11):1216-8. PMID: 18541830.
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  261. Murabito JM, Pencina MJ, Zhu L, Kelly-Hayes M, Shrader P, D'Agostino RB. Temporal trends in self-reported functional limitations and physical disability among the community-dwelling elderly population: the Framingham heart study. Am J Public Health. 2008 Jul; 98(7):1256-62. PMID: 18511716.
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  262. Cooper CJ, Haller ST, Colyer W, Steffes M, Burket MW, Thomas WJ, Safian R, Reddy B, Brewster P, Ankenbrandt MA, Virmani R, Dippel E, Rocha-Singh K, Murphy TP, Kennedy DJ, Shapiro JI, D'Agostino RD, Pencina MJ, Khuder S. Embolic protection and platelet inhibition during renal artery stenting. Circulation. 2008 May 27; 117(21):2752-60. PMID: 18490527.
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  263. Fox CS, Pencina MJ, Wilson PW, Paynter NP, Vasan RS, D'Agostino RB. Lifetime risk of cardiovascular disease among individuals with and without diabetes stratified by obesity status in the Framingham heart study. Diabetes Care. 2008 Aug; 31(8):1582-4. PMID: 18458146.
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  264. Fox CS, Pencina MJ, D'Agostino RB, Murabito JM, Seely EW, Pearce EN, Vasan RS. Relations of thyroid function to body weight: cross-sectional and longitudinal observations in a community-based sample. Arch Intern Med. 2008 Mar 24; 168(6):587-92. PMID: 18362250.
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