Vasan Ramachandran | Profiles RNS

Vasan S. Ramachandran, MD

Adjunct Professor

Boston University Chobanian & Avedisian School of Medicine

Medicine

Preventive Medicine & Epidemiology

MD, All India Institute of Medical Science (AIIMS)
MBBS, All India Institute of Medical Science (AIIMS)
DM, All India Institute of Medical Science (AIIMS)

Websites

	Inaugural Dean of The University of Texas School of Public Health San Antonio
	Vasan Ramachandran Named Coffman Professor in Vascular Medicine
	ResearchGate

ORCID : 0000-0001-7357-5970

Vasan S. Ramachandran, M.D., Principal Investigator and Director of the Framingham Heart Study (FHS), and Principal Investigator of the Risk Underlying Rural Areas Longitudinal Study (RURAL).

Dr. Ramachandran is an Adjunct Professor of Medicine and Epidemiology at BUSM/BUSPH, and Dean of the University of Texas School of Public Health San Antonio. He is a trained cardiologist with subspecialty training in echocardiography. He is a fellow of the AHA Councils on Epidemiology and Prevention and Functional Genomics and Translational Biology, and a fellow of the American College of Cardiology (ACC). Dr. Ramachandran has extensive experience in supervising trainees at many levels and has taught the foundational core course on Cardiovascular Epidemiology at BUSPH (EP751). He has several active R01 grants from the NHLBI/NIDDK/NIA, received two K24 Mid-Career Investigator mentoring grants from the NHLBI, and has mentored several K23 awardees. Overall, he has supervised over 75 trainees during the past 20 years (~40% women, 25% non-White); most are in key positions in academia. He received the Outstanding Mentor awards from the Department of Medicine, BUSM, and the AHA Council on Epidemiology and Prevention, the prestigious AHA Population Science Award in 2014 and the AHA Distinguished Scientist Award in 2021.

Importantly, Dr. Ramachandran’s own peer-reviewed funding spans thematic areas of genetics and genomics, cardiac and vascular remodeling, novel biomarkers, systems biology including proteomics and metabolomics, microbiome, and stem cell biology. He has a 25-year history in research in cardiovascular epidemiology, including the two years he trained as a FHS fellow (1993-1995). He established the first School of Public Health in Kerala, India, between 1996-1998, serving as its inaugural director and the coordinator of its MPH program. He is the founding member and leader of the international EchoGen consortium, and chairs the Steering Committee of the Chronic Kidney Disease Biomarker Consortium funded by the NIDDK (U01DK085689). He is recognized internationally for translational research in cardiovascular epidemiology and lectures regularly at the AHA early career session on “how to develop a career in translational research and epidemiology/genetics.” He is a Trained Mentor and has been been a past member of the NIH Cardiovascular and Sleep (CASE) SRG, and an active reviewer of grants for national and international funding agencies. He served for many years on the NHLBI panel for reviewing K23-K24-K25 career development grants. He served as an Associate Editor for Circulation, and the founding Editor-in-Chief of Circulation: Cardiovascular Genetics. He directs the Center for Integrative Transdisciplinary Epidemiology within BUSM, that hosts multiple epidemiological datasets, including from multiple cohort studies, national surveys (NHANES), administrative databases and electronic health records; this center will be a valuable data source for trainees.

For the last 25 years, Dr. Ramachandran has focused his research on A) the genetic and non-genetic epidemiology of congestive heart failure, including identifying risk factors for the disease, characterizing the subgroups with diastolic heart failure, asymptomatic LV systolic and diastolic dysfunction, and evaluating the role of LV remodeling; B) population-based vascular testing and echocardiography, including identifying biological, environmental, and genetic determinants (correlates) of cardiac structure and function; normative standards; detailed assessment of biomarkers of the process of LV remodeling, including but not limited to role of natriuretic peptides, insulin resistance, cardiac extracellular matrix markers, oxidative stress, inflammation, growth factors; genetics of LV remodeling, LA and aortic structure and gene-environment interactions; brachial artery endothelial function, its correlates and tonometric assessment of large artery function; C) genetic and non-genetic epidemiology of high blood pressure, including characterizing the lifetime risk, rates of progression and risks associated with various degrees of elevation; large artery stiffness and function and role in systolic hypertension in the elderly; genetics of high blood pressure and large artery function; D) CVD risk estimation in the short, medium- and long-term, with novel biomarkers including genomic biomarkers; and E) rural health disparities via the RURAL cohort study.

Multidisciplinary Training Program in Cardiovascular Epidemiology
04/01/2021 - 03/31/2026 (PI of Sub-Project / SP)
PI: Vanessa Xanthakis, PhD
NIH/National Heart, Lung, and Blood Institute
5T32HL125232-09

Myocardial Radiomics and Mechanics in the Pathology and Prognosis of Cardiovascular Disease
03/15/2021 - 02/28/2026 (PI of Sub-Project / SP)
Beth Israel Deaconess Medical Center, Inc. NIH NHLBI
5R01HL155717-03

Framingham Heart Study
04/01/2019 - 06/30/2025 (PI of Sub-Project / SP)
PI: Joanne M. Murabito, MD
NIH/National Heart, Lung, and Blood Institute

Multidimensional Assessment of Brain Health as A Marker of Dementia Risk and Resilience in the Framingham Study
09/15/2020 - 05/31/2025 (PI of Sub-Project / SP)
University of Texas Health Science Center at San Antonio NIH NIA
5R01AG066524-05

Return of Genomic Results and Estimating Penetrance in Population-Based Cohorts
08/01/2019 - 06/30/2024 (PI of Sub-Project / SP)
Broad Institute, Inc., The NIH NHLBI
1R01HL143295-04

Mediators of Systemic Inflammation and Heart Failure Risk in the Community
04/01/2019 - 03/31/2024 (PI of Sub-Project / SP)
Cedars-Sinai Medical Center NIH NHLBI
5R01HL143227-04

Cardio-metabolic risk in Multi-ethnic Physical Activity and Sedentary Behavior Study
12/15/2016 - 11/30/2023 (Multi-PI)
PI: Vasan S. Ramachandran, MD
Albert Einstein College of Medicine NIH NHLBI
5R01HL136266-05

Neighborhoods and Cardiovascular Risk and Resilience in Rural Communities
04/01/2022 - 10/31/2022 (Subcontract PI)
The Regents of the University of California (University of California, Berkeley) NIH NHLBI
1R01HL157820-01A1

Epidemiologic Determinants of Cardiac Structure and Function in Rural Residents: RURAL ECHO
02/21/2022 - 10/31/2022 (Subcontract PI)
Duke University NIH NHLBI
1R01HL157531-01A1

RURAL: Risk Underlying Rural Areas Longitudinal Cohort Study
04/01/2019 - 10/31/2022 (Multi-PI)
PI: Vasan S. Ramachandran, MD
NIH/National Heart, Lung, and Blood Institute
5U01HL146382-04

Showing 10 of 57 results. Show All Results

Population-Based Reference Ranges for Estradiol and Estrone in Men
04/07/2012 - 07/31/2012 (Activity-level PI)
PI: Shalender Bhasin, MBBS
NIH-NIDDK
1R01 DK092938-01A1

Title

Yr	Title	Project-Sub Proj
2024	Genetic Architecture of Cardiac Structure and Function and Its Impact on Heart Failure	5R01HL160793-03
2024	Epidemiology of blood pressure responses to perturbations: Correlates and prognosis for vascular risk, end-organ damage, cognitive aging and preclinical Alzheimer's disease	5R01AG075703-03
2024	Multidimensional Assessment of Brain Health as A Marker of Dementia Risk and Resilience	5R01AG066524-05
2024	RURAL: Risk Underlying Rural Areas Longitudinal Cohort Study	3U01HL146382-07S1
2024	RURAL: Risk Underlying Rural Areas Longitudinal Cohort Study	5U01HL146382-07
2023	Aortic stiffness, wave reflection, and cerebrovascular flow pulsatility: relations with brain small vessel disease and cognitive function in a middle-aged cohort	1RF1AG079390-01A1
2023	Development of a cloud-based analytical tool for polygenic risk score and its implication in heart failure research.	3R01HL160793-02S1
2023	Genetic Architecture of Cardiac Structure and Function and Its Impact on Heart Failure	5R01HL160793-02
2023	Epidemiology of blood pressure responses to perturbations: Correlates and prognosis for vascular risk, end-organ damage, cognitive aging and preclinical Alzheimer's disease	7R01AG075703-02
2023	Multidimensional Assessment of Brain Health as A Marker of Dementia Risk and Resilience	5R01AG066524-04

Showing 10 of 125 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Yu Z, Vromman A, Nguyen NQH, Schuermans A, Rentz T, Vellarikkal SK, Uddin MM, Niroula A, Griffin G, Honigberg MC, Lin AE, Gibson CJ, Katz DH, Tahir U, Fang S, Haidermota S, Ganesh S, Antoine T, Weinstock J, Austin TR, Ramachandran VS, Peloso GM, Hornsby W, Ganz P, Manson JE, Haring B, Kooperberg CL, Reiner AP, Bis JC, Psaty BM, Min YI, Correa A, Lange LA, Post WS, Rotter JI, Rich SS, Wilson JG, Ebert BL, Yu B, Ballantyne CM, Coresh J, Sankaran VG, Bick AG, Jaiswal S, Gerszten RE, Libby P, Gupta RM, Natarajan P. Human Plasma Proteomic Profile of Clonal Hematopoiesis. bioRxiv. 2024 Oct 31. PMID: 39554199; PMCID: PMC11565774; DOI: 10.1101/2023.07.25.550557;

Yao Z, Tasdighi E, Dardari ZA, Erhabor J, Jha KK, Osuji N, Rajan T, Boakye E, Rodriguez CJ, Lima JAC, Judd SE, Feldman T, Fialkow JA, Vasan RS, El Shahawy O, Benjamin EJ, Bhatnagar A, DeFilippis AP, Nasir K, Blaha MJ. Use of e-cigarettes, traditional combustible cigarettes, and high sensitivity C-reactive protein: The Cross Cohort Collaboration. Am Heart J. 2025 Feb; 280:1-6.View Related Profiles.

Benjamin, Emelia
Ramachandran, Vasan

PMID: 39461654

Hameed P S, Kotakonda H, Sharma S, Nandishaiah R, Katagihallimath N, Rao R, Sadler C, Slater I, Morton M, Chandrasekaran A, Griffen E, Pillai D, Reddy S, Bharatham N, Venkatesan S, Jonnalagadda V, Jayaraman R, Nanjundappa M, Sharma M, Raveendran S, Rajagopal S, Tumma H, Watters A, Becker H, Lindley J, Flamm R, Huband M, Sahm D, Hackel M, Mathur T, Kolamunnage-Dona R, Unsworth J, Mcentee L, Farrington N, Manickam D, Chandrashekara N, Jayachandiran S, Reddy H, Shanker S, Richard V, Thomas T, Nagaraj S, Datta S, Sambandamurthy V, Ramachandran V, Clay R, Tomayko J, Das S, V B. BWC0977, a broad-spectrum antibacterial clinical candidate to treat multidrug resistant infections. Nat Commun. 2024 Sep 18; 15(1):8202. PMID: 39294149; PMCID: PMC11410943; DOI: 10.1038/s41467-024-52557-2;

Gaye B, Valentin E, Xanthakis V, Perier MC, Celermajer DS, Shipley M, Marijon E, Song RJ, Empana JP, Ramachandran VS, Jouven X. Author Correction: Association between change in heart rate over years and life span in the Paris Prospective 1, the Whitehall 1, and Framingham studies. Sci Rep. 2024 Sep 06; 14(1):20868.View Related Profiles.

Xanthakis, Vanessa
Ramachandran, Vasan

PMID: 39242738; PMCID: PMC11379920; DOI: 10.1038/s41598-024-72000-2;

Gaye B, Valentin E, Xanthakis V, Perier MC, Celermajer DS, Shipley M, Marijon E, Song RJ, Empana JP, Ramachandran VS, Jouven X. Association between change in heart rate over years and life span in the Paris Prospective 1, the Whitehall 1, and Framingham studies. Sci Rep. 2024 Aug 29; 14(1):20052.View Related Profiles.

Xanthakis, Vanessa
Ramachandran, Vasan

PMID: 39209972; PMCID: PMC11362490; DOI: 10.1038/s41598-024-70806-8;

Wang N, Ockerman FP, Zhou LY, Grove ML, Alkis T, Barnard J, Bowler RP, Clish CB, Chung S, Drzymalla E, Evans AM, Franceschini N, Gerszten RE, Gillman MG, Hutton SR, Kelly RS, Kooperberg C, Larson MG, Lasky-Su J, Meyers DA, Woodruff PG, Reiner AP, Rich SS, Rotter JI, Silverman EK, Ramachandran VS, Weiss ST, Wong KE, Wood AC, Wu L, Yarden R, Blackwell TW, Smith AV, Chen H, Raffield LM, Yu B. Genetic Architecture and Analysis Practices of Circulating Metabolites in the NHLBI Trans-Omics for Precision Medicine (TOPMed) Program. bioRxiv. 2024 Aug 26. PMID: 39211135; PMCID: PMC11361093; DOI: 10.1101/2024.07.23.604849;

Charisis S, Short MI, Bernal R, Kautz TF, Treviño HA, Mathews J, Dediós AGV, Muhammad JAS, Luckey AM, Aslam A, Himali JJ, Shipp EL, Habes M, Beiser AS, DeCarli C, Scarmeas N, Ramachandran VS, Seshadri S, Maillard P, Satizabal CL. Leptin bioavailability and markers of brain atrophy and vascular injury in the middle age. Alzheimers Dement. 2024 Sep; 20(9):5849-5860.View Related Profiles.

Beiser, Alexa
Satizabal, Claudia
Himali, Jayandra
Seshadri, Sudha
Ramachandran, Vasan

PMID: 39132759; PMCID: PMC11497668; DOI: 10.1002/alz.13879;

Dubin RF, Deo R, Ren Y, Wang J, Pico AR, Mychaleckyj JC, Kozlitina J, Arthur V, Lee H, Shah A, Feldman H, Bansal N, Zelnick L, Rao P, Sukul N, Raj DS, Mehta R, Rosas SE, Bhat Z, Weir MR, He J, Chen J, Kansal M, Kimmel PL, Ramachandran VS, Waikar SS, Segal MR, Ganz P. Incident heart failure in chronic kidney disease: proteomics informs biology and risk stratification. Eur Heart J. 2024 Aug 09; 45(30):2752-2767.View Related Profiles.

Waikar, Sushrut
Ramachandran, Vasan

PMID: 38757788; PMCID: PMC11313584; DOI: 10.1093/eurheartj/ehae288;

Lau ES, Zhao Y, Benjamin EJ, Ramachandran VS, Xanthakis V, Cheng S, Ho JE. Sex Differences in Left Ventricular Function and Cardiac Mechanics. J Am Heart Assoc. 2024 Jun 18; 13(12):e035781.View Related Profiles.

Benjamin, Emelia
Xanthakis, Vanessa
Ramachandran, Vasan

PMID: 38842280; PMCID: PMC11255751; DOI: 10.1161/JAHA.124.035781;

Li T, Grams ME, Inker LA, Chen J, Rhee EP, Warady BA, Levey AS, Denburg MR, Furth SL, Ramachandran VS, Kimmel PL, Coresh J. Consistency of metabolite associations with measured glomerular filtration rate in children and adults. Clin Kidney J. 2024 Jun; 17(6):sfae108. PMID: 38859934; PMCID: PMC11163224; DOI: 10.1093/ckj/sfae108;

Showing 10 of 821 results. Show More

Zhou JC, Zhao Y, Bello N, Benjamin EJ, Ramachandran VS, Levy D, Cheng S, Murabito JM, Ho JE, Lau ES. Infertility and Subclinical Antecedents of Heart Failure With Preserved Ejection Fraction in the Framingham Heart Study. J Card Fail. 2024 Mar; 30(3):513-515.View Related Profiles.

Benjamin, Emelia
Murabito, Joanne
Ramachandran, Vasan

PMID: 37979670; PMCID: PMC10947933; DOI: 10.1016/j.cardfail.2023.10.482;

Weber JE, Ahmadi M, Boldt LH, Eckardt KU, Edelmann F, Gerhardt H, Grittner U, Haubold K, Hübner N, Kollmus-Heege J, Landmesser U, Leistner DM, Mai K, Müller DN, Nolte CH, Pieske B, Piper SK, Rattan S, Rauch G, Schmidt S, Schmidt-Ott KM, Schönrath K, Schulz-Menger J, Schweizerhof O, Siegerink B, Spranger J, Ramachandran VS, Witzenrath M, Endres M, Pischon T. Protocol of the Berlin Long-term Observation of Vascular Events (BeLOVE): a prospective cohort study with deep phenotyping and long-term follow up of cardiovascular high-risk patients. BMJ Open. 2023 Oct 31; 13(10):e076415. PMID: 37907297; PMCID: PMC10618970; DOI: 10.1136/bmjopen-2023-076415;

Westerman KE, Walker ME, Gaynor SM, Wessel J, DiCorpo D, Ma J, Alonso A, Aslibekyan S, Baldridge AS, Bertoni AG, Biggs ML, Brody JA, Chen YI, Dupuis J, Goodarzi MO, Guo X, Hasbani NR, Heath A, Hidalgo B, Irvin MR, Johnson WC, Kalyani RR, Lange L, Lemaitre RN, Liu CT, Liu S, Moon JY, Nassir R, Pankow JS, Pettinger M, Raffield LM, Rasmussen-Torvik LJ, Selvin E, Senn MK, Shadyab AH, Smith AV, Smith NL, Steffen L, Talegakwar S, Taylor KD, de Vries PS, Wilson JG, Wood AC, Yanek LR, Yao J, Zheng Y, Boerwinkle E, Morrison AC, Fornage M, Russell TP, Psaty BM, Levy D, Heard-Costa NL, Ramachandran VS, Mathias RA, Arnett DK, Kaplan R, North KE, Correa A, Carson A, Rotter JI, Rich SS, Manson JE, Reiner AP, Kooperberg C, Florez JC, Meigs JB, Merino J, Tobias DK, Chen H, Manning AK. Investigating Gene-Diet Interactions Impacting the Association Between Macronutrient Intake and Glycemic Traits. Diabetes. 2023 May 01; 72(5):653-665.View Related Profiles.

Liu, Ching-Ti
Dupuis, Josee
Walker, Maura
Heard-Costa, Nancy
Ramachandran, Vasan

PMID: 36791419; PMCID: PMC10130485; DOI: 10.2337/db22-0851;

Satizabal CL, Himali JJ, Beiser AS, Ramachandran V, Melo van Lent D, Himali D, Aparicio HJ, Maillard P, DeCarli CS, Harris WS, Seshadri S. Association of Red Blood Cell Omega-3 Fatty Acids With MRI Markers and Cognitive Function in Midlife: The Framingham Heart Study. Neurology. 2022 Dec 05; 99(23):e2572-e2582.View Related Profiles.

Beiser, Alexa
Satizabal, Claudia
Aparicio, Hugo
Himali, Jayandra
Seshadri, Sudha
Ramachandran, Vasan

PMID: 36198518; PMCID: PMC9754651; DOI: 10.1212/WNL.0000000000201296;

Pirruccello JP, Lin H, Khurshid S, Nekoui M, Weng LC, Ramachandran VS, Isselbacher EM, Benjamin EJ, Lubitz SA, Lindsay ME, Ellinor PT. Development of a Prediction Model for Ascending Aortic Diameter Among Asymptomatic Individuals. JAMA. 2022 11 15; 328(19):1935-1944.View Related Profiles.

Benjamin, Emelia
Lin, Honghuang
Ramachandran, Vasan

PMID: 36378208; PMCID: PMC9667326; DOI: 10.1001/jama.2022.19701;

Cohen JB, Mitchell GF, Gill D, Burgess S, Rahman M, Hanff TC, Ramachandran VS, Mutalik KM, Townsend RR, Chirinos JA. Arterial Stiffness and Diabetes Risk in Framingham Heart Study and UK Biobank. Circ Res. 2022 Sep 02; 131(6):545-554. PMID: 35946401; PMCID: PMC7613487; DOI: 10.1161/CIRCRESAHA.122.320796;

Schwartz B, Schou M, Barrillas Lara IM, Monahan K, Helm R, Køber L, Gislason GH, Ramachandran VS, Torp-Pedersen C, Andersson C. Prognostic importance of atrial fibrillation in heart failure according to time elapsed since diagnosis. Heart Rhythm O2. 2022 Aug; 3(4):430-432.View Related Profiles.

Schwartz, Brian
Monahan, Kevin
Helm, Robert
Ramachandran, Vasan

PMID: 36097453; PMCID: PMC9463685; DOI: 10.1016/j.hroo.2022.04.008;

Vasan RS, Enserro DM, Beiser AS, Xanthakis V. Lifetime Risk of Heart Failure Among Participants in the Framingham Study. J Am Coll Cardiol. 2022 01 25; 79(3):250-263.View Related Profiles.

Beiser, Alexa
Xanthakis, Vanessa
Ramachandran, Vasan

PMID: 35057911; PMCID: PMC8820638; DOI: 10.1016/j.jacc.2021.10.043;

Lee AM, Hu J, Xu Y, Abraham AG, Xiao R, Coresh J, Rebholz C, Chen J, Rhee EP, Feldman HI, Ramachandran VS, Kimmel PL, Warady BA, Furth SL, Denburg MR. Using Machine Learning to Identify Metabolomic Signatures of Pediatric Chronic Kidney Disease Etiology. J Am Soc Nephrol. 2022 02; 33(2):375-386. PMID: 35017168; PMCID: PMC8819986; DOI: 10.1681/ASN.2021040538;

Vasan RS, van den Heuvel E. Differences in estimates for 10-year risk of cardiovascular disease in Black versus White individuals with identical risk factor profiles using pooled cohort equations: an in silico cohort study. Lancet Digit Health. 2022 01; 4(1):e55-e63.View Related Profiles.

Van Den Heuvel, Edwin
Ramachandran, Vasan

PMID: 34952676; PMCID: PMC8715354; DOI: 10.1016/S2589-7500(21)00236-3;

Schmidt IM, Srivastava A, Sabbisetti V, McMahon GM, He J, Chen J, Kusek JW, Taliercio J, Ricardo AC, Hsu CY, Kimmel PL, Liu KD, Mifflin TE, Nelson RG, Vasan RS, Xie D, Zhang X, Palsson R, Stillman IE, Rennke HG, Feldman HI, Bonventre JV, Waikar SS. Plasma Kidney Injury Molecule 1 in CKD: Findings From the Boston Kidney Biopsy Cohort and CRIC Studies. Am J Kidney Dis. 2022 02; 79(2):231-243.e1.View Related Profiles.

Schmidt, Insa
Waikar, Sushrut
Ramachandran, Vasan

PMID: 34175376; PMCID: PMC8709877; DOI: 10.1053/j.ajkd.2021.05.013;

Vasan RS, Urbina EM, Jin L, Xanthakis V. Prognostic Significance of Echocardiographic Measures of Cardiac Remodeling in the Community. Curr Cardiol Rep. 2021 06 03; 23(7):86.View Related Profiles.

Xanthakis, Vanessa
Ramachandran, Vasan

PMID: 34081212

Sanders JL, Putman RK, Dupuis J, Xu H, Murabito JM, Araki T, Nishino M, Benjamin EJ, Levy DL, Ramachandran VS, Washko GR, Curtis JL, Freeman CM, Bowler RP, Hatabu H, O'Connor GT, Hunninghake GM. The Association of Aging Biomarkers, Interstitial Lung Abnormalities, and Mortality. Am J Respir Crit Care Med. 2021 05 01; 203(9):1149-1157.View Related Profiles.

Benjamin, Emelia
O'Connor, George
Murabito, Joanne
Dupuis, Josee
Ramachandran, Vasan

PMID: 33080140; PMCID: PMC8314902; DOI: 10.1164/rccm.202007-2993OC;

Surendran P, Feofanova EV, Lahrouchi N, Ntalla I, Karthikeyan S, Cook J, Chen L, Mifsud B, Yao C, Kraja AT, Cartwright JH, Hellwege JN, Giri A, Tragante V, Thorleifsson G, Liu DJ, Prins BP, Stewart ID, Cabrera CP, Eales JM, Akbarov A, Auer PL, Bielak LF, Bis JC, Braithwaite VS, Brody JA, Daw EW, Warren HR, Drenos F, Nielsen SF, Faul JD, Fauman EB, Fava C, Ferreira T, Foley CN, Franceschini N, Gao H, Giannakopoulou O, Giulianini F, Gudbjartsson DF, Guo X, Harris SE, Havulinna AS, Helgadottir A, Huffman JE, Hwang SJ, Kanoni S, Kontto J, Larson MG, Li-Gao R, Lindström J, Lotta LA, Lu Y, Luan J, Mahajan A, Malerba G, Masca NGD, Mei H, Menni C, Mook-Kanamori DO, Mosen-Ansorena D, Müller-Nurasyid M, Paré G, Paul DS, Perola M, Poveda A, Rauramaa R, Richard M, Richardson TG, Sepúlveda N, Sim X, Smith AV, Smith JA, Staley JR, Stanáková A, Sulem P, Thériault S, Thorsteinsdottir U, Trompet S, Varga TV, Velez Edwards DR, Veronesi G, Weiss S, Willems SM, Yao J, Young R, Yu B, Zhang W, Zhao JH, Zhao W, Zhao W, Evangelou E, Aeschbacher S, Asllanaj E, Blankenberg S, Bonnycastle LL, Bork-Jensen J, Brandslund I, Braund PS, Burgess S, Cho K, Christensen C, Connell J, Mutsert R, Dominiczak AF, Dörr M, Eiriksdottir G, Farmaki AE, Gaziano JM, Grarup N, Grove ML, Hallmans G, Hansen T, Have CT, Heiss G, Jørgensen ME, Jousilahti P, Kajantie E, Kamat M, Käräjämäki A, Karpe F, Koistinen HA, Kovesdy CP, Kuulasmaa K, Laatikainen T, Lannfelt L, Lee IT, Lee WJ, Linneberg A, Martin LW, Moitry M, Nadkarni G, Neville MJ, Palmer CNA, Papanicolaou GJ, Pedersen O, Peters J, Poulter N, Rasheed A, Rasmussen KL, Rayner NW, Mägi R, Renström F, Rettig R, Rossouw J, Schreiner PJ, Sever PS, Sigurdsson EL, Skaaby T, Sun YV, Sundstrom J, Thorgeirsson G, Esko T, Trabetti E, Tsao PS, Tuomi T, Turner ST, Tzoulaki I, Vaartjes I, Vergnaud AC, Willer CJ, Wilson PWF, Witte DR, Yonova-Doing E, Zhang H, Aliya N, Almgren P, Amouyel P, Asselbergs FW, Barnes MR, Blakemore AI, Boehnke M, Bots ML, Bottinger EP, Buring JE, Chambers JC, Chen YI, Chowdhury R, Conen D, Correa A, Davey Smith G, Boer RA, Deary IJ, Dedoussis G, Deloukas P, Di Angelantonio E, Elliott P, Felix SB, Ferrières J, Ford I, Fornage M, Franks PW, Franks S, Frossard P, Gambaro G, Gaunt TR, Groop L, Gudnason V, Harris TB, Hayward C, Hennig BJ, Herzig KH, Ingelsson E, Tuomilehto J, Järvelin MR, Jukema JW, Kardia SLR, Kee F, Kooner JS, Kooperberg C, Launer LJ, Lind L, Loos RJF, Majumder AAS, Laakso M, McCarthy MI, Melander O, Mohlke KL, Murray AD, Nordestgaard BG, Orho-Melander M, Packard CJ, Padmanabhan S, Palmas W, Polasek O, Porteous DJ, Prentice AM, Province MA, Relton CL, Rice K, Ridker PM, Rolandsson O, Rosendaal FR, Rotter JI, Rudan I, Salomaa V, Samani NJ, Sattar N, Sheu WH, Smith BH, Soranzo N, Spector TD, Starr JM, Sebert S, Taylor KD, Lakka TA, Timpson NJ, Tobin MD, van der Harst P, van der Meer P, Ramachandran VS, Verweij N, Virtamo J, Völker U, Weir DR, Zeggini E, Charchar FJ, Wareham NJ, Langenberg C, Tomaszewski M, Butterworth AS, Caulfield MJ, Danesh J, Edwards TL, Holm H, Hung AM, Lindgren CM, Liu C, Manning AK, Morris AP, Morrison AC, O'Donnell CJ, Psaty BM, Saleheen D, Stefansson K, Boerwinkle E, Chasman DI, Levy D, Newton-Cheh C, Munroe PB, Howson JMM. Publisher Correction: Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals. Nat Genet. 2021 May; 53(5):762.View Related Profiles.

O'Donnell, Christopher
Liu, Chunyu
Gaziano, J. Michael
Buring, Julie
Larson, Martin
Hwang, Shih-Jen
Ramachandran, Vasan

PMID: 33727701

Tromp J, Paniagua SMA, Lau ES, Allen NB, Blaha MJ, Gansevoort RT, Hillege HL, Lee DE, Levy D, Vasan RS, van der Harst P, van Gilst WH, Larson MG, Shah SJ, de Boer RA, Lam CSP, Ho JE. Age dependent associations of risk factors with heart failure: pooled population based cohort study. BMJ. 2021 03 23; 372:n461.View Related Profiles.

Larson, Martin
Ramachandran, Vasan

PMID: 33758001; PMCID: PMC7986583; DOI: 10.1136/bmj.n461;

Lin BM, Grinde KE, Brody JA, Breeze CE, Raffield LM, Mychaleckyj JC, Thornton TA, Perry JA, Baier LJ, de Las Fuentes L, Guo X, Heavner BD, Hanson RL, Hung YJ, Qian H, Hsiung CA, Hwang SJ, Irvin MR, Jain D, Kelly TN, Kobes S, Lange L, Lash JP, Li Y, Liu X, Mi X, Musani SK, Papanicolaou GJ, Parsa A, Reiner AP, Salimi S, Sheu WH, Shuldiner AR, Taylor KD, Smith AV, Smith JA, Tin A, Vaidya D, Wallace RB, Yamamoto K, Sakaue S, Matsuda K, Kamatani Y, Momozawa Y, Yanek LR, Young BA, Zhao W, Okada Y, Abecasis G, Psaty BM, Arnett DK, Boerwinkle E, Cai J, Yii-Der Chen I, Correa A, Cupples LA, He J, Kardia SL, Kooperberg C, Mathias RA, Mitchell BD, Nickerson DA, Turner ST, Vasan RS, Rotter JI, Levy D, Kramer HJ, Köttgen A, Nhlbi Trans-Omics For Precision Medicine TOPMed Consortium, TOPMed Kidney Working Group, Rich SS, Lin DY, Browning SR, Franceschini N. Whole genome sequence analyses of eGFR in 23,732 people representing multiple ancestries in the NHLBI trans-omics for precision medicine (TOPMed) consortium. EBioMedicine. 2021 Jan; 63:103157.View Related Profiles.

Cupples, L
Hwang, Shih-Jen
Ramachandran, Vasan

PMID: 33418499; PMCID: PMC7804602; DOI: 10.1016/j.ebiom.2020.103157;

Vasan RS, Zachariah JP, Xanthakis V. Life Course Developmental Approach to Cardiovascular Health and Cardiovascular Disease Prevention: Opportunities and Unanswered Questions. J Am Coll Cardiol. 2020 12 08; 76(23):2708-2711.View Related Profiles.

Xanthakis, Vanessa
Ramachandran, Vasan

PMID: 33272364; PMCID: PMC8297517; DOI: 10.1016/j.jacc.2020.10.011;

Surendran P, Feofanova EV, Lahrouchi N, Ntalla I, Karthikeyan S, Cook J, Chen L, Mifsud B, Yao C, Kraja AT, Cartwright JH, Hellwege JN, Giri A, Tragante V, Thorleifsson G, Liu DJ, Prins BP, Stewart ID, Cabrera CP, Eales JM, Akbarov A, Auer PL, Bielak LF, Bis JC, Braithwaite VS, Brody JA, Daw EW, Warren HR, Drenos F, Nielsen SF, Faul JD, Fauman EB, Fava C, Ferreira T, Foley CN, Franceschini N, Gao H, Giannakopoulou O, Giulianini F, Gudbjartsson DF, Guo X, Harris SE, Havulinna AS, Helgadottir A, Huffman JE, Hwang SJ, Kanoni S, Kontto J, Larson MG, Li-Gao R, Lindström J, Lotta LA, Lu Y, Luan J, Mahajan A, Malerba G, Masca NGD, Mei H, Menni C, Mook-Kanamori DO, Mosen-Ansorena D, Müller-Nurasyid M, Paré G, Paul DS, Perola M, Poveda A, Rauramaa R, Richard M, Richardson TG, Sepúlveda N, Sim X, Smith AV, Smith JA, Staley JR, Stanáková A, Sulem P, Thériault S, Thorsteinsdottir U, Trompet S, Varga TV, Velez Edwards DR, Veronesi G, Weiss S, Willems SM, Yao J, Young R, Yu B, Zhang W, Zhao JH, Zhao W, Zhao W, Evangelou E, Aeschbacher S, Asllanaj E, Blankenberg S, Bonnycastle LL, Bork-Jensen J, Brandslund I, Braund PS, Burgess S, Cho K, Christensen C, Connell J, Mutsert R, Dominiczak AF, Dörr M, Eiriksdottir G, Farmaki AE, Gaziano JM, Grarup N, Grove ML, Hallmans G, Hansen T, Have CT, Heiss G, Jørgensen ME, Jousilahti P, Kajantie E, Kamat M, Käräjämäki A, Karpe F, Koistinen HA, Kovesdy CP, Kuulasmaa K, Laatikainen T, Lannfelt L, Lee IT, Lee WJ, Linneberg A, Martin LW, Moitry M, Nadkarni G, Neville MJ, Palmer CNA, Papanicolaou GJ, Pedersen O, Peters J, Poulter N, Rasheed A, Rasmussen KL, Rayner NW, Mägi R, Renström F, Rettig R, Rossouw J, Schreiner PJ, Sever PS, Sigurdsson EL, Skaaby T, Sun YV, Sundstrom J, Thorgeirsson G, Esko T, Trabetti E, Tsao PS, Tuomi T, Turner ST, Tzoulaki I, Vaartjes I, Vergnaud AC, Willer CJ, Wilson PWF, Witte DR, Yonova-Doing E, Zhang H, Aliya N, Almgren P, Amouyel P, Asselbergs FW, Barnes MR, Blakemore AI, Boehnke M, Bots ML, Bottinger EP, Buring JE, Chambers JC, Chen YI, Chowdhury R, Conen D, Correa A, Davey Smith G, Boer RA, Deary IJ, Dedoussis G, Deloukas P, Di Angelantonio E, Elliott P, Felix SB, Ferrières J, Ford I, Fornage M, Franks PW, Franks S, Frossard P, Gambaro G, Gaunt TR, Groop L, Gudnason V, Harris TB, Hayward C, Hennig BJ, Herzig KH, Ingelsson E, Tuomilehto J, Järvelin MR, Jukema JW, Kardia SLR, Kee F, Kooner JS, Kooperberg C, Launer LJ, Lind L, Loos RJF, Majumder AAS, Laakso M, McCarthy MI, Melander O, Mohlke KL, Murray AD, Nordestgaard BG, Orho-Melander M, Packard CJ, Padmanabhan S, Palmas W, Polasek O, Porteous DJ, Prentice AM, Province MA, Relton CL, Rice K, Ridker PM, Rolandsson O, Rosendaal FR, Rotter JI, Rudan I, Salomaa V, Samani NJ, Sattar N, Sheu WH, Smith BH, Soranzo N, Spector TD, Starr JM, Sebert S, Taylor KD, Lakka TA, Timpson NJ, Tobin MD, van der Harst P, van der Meer P, Ramachandran VS, Verweij N, Virtamo J, Völker U, Weir DR, Zeggini E, Charchar FJ, Wareham NJ, Langenberg C, Tomaszewski M, Butterworth AS, Caulfield MJ, Danesh J, Edwards TL, Holm H, Hung AM, Lindgren CM, Liu C, Manning AK, Morris AP, Morrison AC, O'Donnell CJ, Psaty BM, Saleheen D, Stefansson K, Boerwinkle E, Chasman DI, Levy D, Newton-Cheh C, Munroe PB, Howson JMM. Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals. Nat Genet. 2020 12; 52(12):1314-1332.View Related Profiles.

O'Donnell, Christopher
Liu, Chunyu
Gaziano, J. Michael
Buring, Julie
Larson, Martin
Hwang, Shih-Jen
Ramachandran, Vasan

PMID: 33230300; PMCID: PMC7610439; DOI: 10.1038/s41588-020-00713-x;

Khera R, Pandey A, Ayers CR, Carnethon MR, Greenland P, Ndumele CE, Nambi V, Seliger SL, Chaves PHM, Safford MM, Cushman M, Xanthakis V, Vasan RS, Mentz RJ, Correa A, Lloyd-Jones DM, Berry JD, de Lemos JA, Neeland IJ. Performance of the Pooled Cohort Equations to Estimate Atherosclerotic Cardiovascular Disease Risk by Body Mass Index. JAMA Netw Open. 2020 10 01; 3(10):e2023242.View Related Profiles.

Lloyd-Jones, Donald
Xanthakis, Vanessa
Ramachandran, Vasan

PMID: 33119108; PMCID: PMC7596579; DOI: 10.1001/jamanetworkopen.2020.23242;

Cooper LL, Musani SK, Moore JA, Clarke VA, Yano Y, Cobbs K, Tsao CW, Butler J, Hall ME, Hamburg NM, Benjamin EJ, Vasan RS, Mitchell GF, Fox ER. Clinical Associations of Vascular Stiffness, Microvascular Dysfunction, and Prevalent Cardiovascular Disease in a Black Cohort: The Jackson Heart Study. J Am Heart Assoc. 2020 09 15; 9(18):e017018.View Related Profiles.

Benjamin, Emelia
Hamburg, Naomi
Ramachandran, Vasan

PMID: 32873113; PMCID: PMC7726980; DOI: 10.1161/JAHA.120.017018;

Greenberg JH, Abraham AG, Xu Y, Schelling JR, Feldman HI, Sabbisetti VS, Gonzalez MC, Coca S, Schrauben SJ, Waikar SS, Ramachandran VS, Shlipak MG, Warady B, Kimmel PL, Bonventre JV, Denburg M, Parikh CR, Furth S. Plasma Biomarkers of Tubular Injury and Inflammation Are Associated with CKD Progression in Children. J Am Soc Nephrol. 2020 05; 31(5):1067-1077.View Related Profiles.

Waikar, Sushrut
Ramachandran, Vasan

PMID: 32234829; PMCID: PMC7217410; DOI: 10.1681/ASN.2019070723;

So-Armah KA, Lim JK, Lo Re V, Tate JP, Chang CH, Butt AA, Gibert CL, Rimland D, Marconi VC, Goetz MB, Ramachandran V, Brittain E, Long M, Nguyen KL, Rodriguez-Barradas MC, Budoff MJ, Tindle HA, Samet JH, Justice AC, Freiberg MS. FIB-4 stage of liver fibrosis is associated with incident heart failure with preserved, but not reduced, ejection fraction among people with and without HIV or hepatitis C. Prog Cardiovasc Dis. 2020 Mar - Apr; 63(2):184-191.View Related Profiles.

Samet, Jeffrey
So-Armah, Kaku
Long, Michelle
Ramachandran, Vasan

PMID: 32068085; PMCID: PMC7278895; DOI: 10.1016/j.pcad.2020.02.010;

Xu J, Gaddis NC, Bartz TM, Hou R, Manichaikul AW, Pankratz N, Smith AV, Sun F, Terzikhan N, Markunas CA, Patchen BK, Schu M, Beydoun MA, Brusselle GG, Eiriksdottir G, Zhou X, Wood AC, Graff M, Harris TB, Ikram MA, Jacobs DR, Launer LJ, Lemaitre RN, O'Connor GT, Oelsner EC, Psaty BM, Vasan RS, Rohde RR, Rich SS, Rotter JI, Seshadri S, Smith LJ, Tiemeier H, Tsai MY, Uitterlinden AG, Voruganti VS, Xu H, Zilhão NR, Fornage M, Zillikens MC, London SJ, Barr RG, Dupuis J, Gharib SA, Gudnason V, Lahousse L, North KE, Steffen LM, Cassano PA, Hancock DB. Omega-3 Fatty Acids and Genome-Wide Interaction Analyses Reveal DPP10-Pulmonary Function Association. Am J Respir Crit Care Med. 2019 03 01; 199(5):631-642.View Related Profiles.

O'Connor, George
Dupuis, Josee
Seshadri, Sudha
Ramachandran, Vasan

PMID: 30199657; PMCID: PMC6396866; DOI: 10.1164/rccm.201802-0304OC;

Harris WS, Tintle NL, Ramachandran VS. Erythrocyte n-6 Fatty Acids and Risk for Cardiovascular Outcomes and Total Mortality in the Framingham Heart Study. Nutrients. 2018 Dec 19; 10(12). PMID: 30572606; PMCID: PMC6316092; DOI: 10.3390/nu10122012;

Zekavat SM, Ruotsalainen S, Handsaker RE, Alver M, Bloom J, Poterba T, Seed C, Ernst J, Chaffin M, Engreitz J, Peloso GM, Manichaikul A, Yang C, Ryan KA, Fu M, Johnson WC, Tsai M, Budoff M, Vasan RS, Cupples LA, Rotter JI, Rich SS, Post W, Mitchell BD, Correa A, Metspalu A, Wilson JG, Salomaa V, Kellis M, Daly MJ, Neale BM, McCarroll S, Surakka I, Esko T, Ganna A, Ripatti S, Kathiresan S, Natarajan P. Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries. Nat Commun. 2018 07 04; 9(1):2606.View Related Profiles.

Peloso, Gina
Cupples, L
Ramachandran, Vasan

PMID: 29973585; PMCID: PMC6031652; DOI: 10.1038/s41467-018-04668-w;

de Boer RA, Nayor M, deFilippi CR, Enserro D, Bhambhani V, Kizer JR, Blaha MJ, Brouwers FP, Cushman M, Lima JAC, Bahrami H, van der Harst P, Wang TJ, Gansevoort RT, Fox CS, Gaggin HK, Kop WJ, Liu K, Vasan RS, Psaty BM, Lee DS, Hillege HL, Bartz TM, Benjamin EJ, Chan C, Allison M, Gardin JM, Januzzi JL, Shah SJ, Levy D, Herrington DM, Larson MG, van Gilst WH, Gottdiener JS, Bertoni AG, Ho JE. Association of Cardiovascular Biomarkers With Incident Heart Failure With Preserved and Reduced Ejection Fraction. JAMA Cardiol. 2018 03 01; 3(3):215-224.View Related Profiles.

Benjamin, Emelia
Larson, Martin
Nayor, Matthew
Ramachandran, Vasan

PMID: 29322198; PMCID: PMC5862778; DOI: 10.1001/jamacardio.2017.4987;

Nayor M, Duncan MS, Musani SK, Xanthakis V, LaValley MP, Larson MG, Fox ER, Vasan RS. Incidence of cardiovascular disease in individuals affected by recent changes to US blood pressure treatment guidelines. J Hypertens. 2018 02; 36(2):436-443.View Related Profiles.

Larson, Martin
Nayor, Matthew
LaValley, Michael
Xanthakis, Vanessa
Ramachandran, Vasan

PMID: 29084083; PMCID: PMC6062206; DOI: 10.1097/HJH.0000000000001570;

Jørgensen ME, Andersson C, Vasan RS, Køber L, Abdulla J. Characteristics and prognosis of heart failure with improved compared with persistently reduced ejection fraction: A systematic review and meta-analyses. Eur J Prev Cardiol. 2018 03; 25(4):366-376. PMID: 29313369; DOI: 10.1177/2047487317750437;

Weinstein G, Zelber-Sagi S, Preis SR, Beiser AS, DeCarli C, Speliotes EK, Satizabal CL, Vasan RS, Seshadri S. Association of Nonalcoholic Fatty Liver Disease With Lower Brain Volume in Healthy Middle-aged Adults in the Framingham Study. JAMA Neurol. 2018 01 01; 75(1):97-104.View Related Profiles.

Beiser, Alexa
Satizabal, Claudia
Weinstein, Galit
Preis, Sarah
Seshadri, Sudha
Ramachandran, Vasan

PMID: 29159396; PMCID: PMC5833484; DOI: 10.1001/jamaneurol.2017.3229;

Sarnowski C, Satizabal CL, DeCarli C, Pitsillides AN, Cupples LA, Vasan RS, Wilson JG, Bis JC, Fornage M, Beiser AS, DeStefano AL, Dupuis J, Seshadri S. Whole genome sequence analyses of brain imaging measures in the Framingham Study. Neurology. 2018 01 16; 90(3):e188-e196.View Related Profiles.

Beiser, Alexa
DeStefano, Anita
Sarnowski, Chloe
Satizabal, Claudia
Dupuis, Josee
Cupples, L
Yang, Qiong
Seshadri, Sudha
Ramachandran, Vasan

PMID: 29282330; PMCID: PMC5772158; DOI: 10.1212/WNL.0000000000004820;

Zachariah JP, Rong J, Larson MG, Hamburg NM, Benjamin EJ, Vasan RS, Mitchell GF. Metabolic Predictors of Change in Vascular Function: Prospective Associations From a Community-Based Cohort. Hypertension. 2018 02; 71(2):237-242.View Related Profiles.

Benjamin, Emelia
Larson, Martin
Hamburg, Naomi
Ramachandran, Vasan

PMID: 29279312; PMCID: PMC5764805; DOI: 10.1161/HYPERTENSIONAHA.117.10054;

Benson MD, Yang Q, Ngo D, Zhu Y, Shen D, Farrell LA, Sinha S, Keyes MJ, Vasan RS, Larson MG, Smith JG, Wang TJ, Gerszten RE. Genetic Architecture of the Cardiovascular Risk Proteome. Circulation. 2018 03 13; 137(11):1158-1172.View Related Profiles.

Larson, Martin
Yang, Qiong
Ramachandran, Vasan

PMID: 29258991; PMCID: PMC5849518; DOI: 10.1161/CIRCULATIONAHA.117.029536;

Ko D, Preis SR, Lubitz SA, McManus DD, Vasan RS, Hamburg NM, Benjamin EJ, Mitchell GF. Relation of Orthostatic Hypotension With New-Onset Atrial Fibrillation (From the Framingham Heart Study). Am J Cardiol. 2018 03 01; 121(5):596-601.View Related Profiles.

Ko, Darae
Benjamin, Emelia
Hamburg, Naomi
Preis, Sarah
Ramachandran, Vasan

PMID: 29290367; PMCID: PMC5843374; DOI: 10.1016/j.amjcard.2017.11.036;

Bhambhani V, Kizer JR, Lima JAC, van der Harst P, Bahrami H, Nayor M, de Filippi CR, Enserro D, Blaha MJ, Cushman M, Wang TJ, Gansevoort RT, Fox CS, Gaggin HK, Kop WJ, Liu K, Vasan RS, Psaty BM, Lee DS, Brouwers FP, Hillege HL, Bartz TM, Benjamin EJ, Chan C, Allison M, Gardin JM, Januzzi JL, Levy D, Herrington DM, van Gilst WH, Bertoni AG, Larson MG, de Boer RA, Gottdiener JS, Shah SJ, Ho JE. Predictors and outcomes of heart failure with mid-range ejection fraction. Eur J Heart Fail. 2018 04; 20(4):651-659.View Related Profiles.

Benjamin, Emelia
Larson, Martin
Nayor, Matthew
Ramachandran, Vasan

PMID: 29226491; PMCID: PMC5899688; DOI: 10.1002/ejhf.1091;

Adams S, Conner S, Himali JJ, Beiser A, Vasan RS, Seshadri S, Pase MP. Vascular risk factor burden and new-onset depression in the community. Prev Med. 2018 06; 111:348-350.View Related Profiles.

Beiser, Alexa
Himali, Jayandra
Seshadri, Sudha
Ramachandran, Vasan

PMID: 29197532; PMCID: PMC5930122; DOI: 10.1016/j.ypmed.2017.11.022;

Maas R, Xanthakis V, Göen T, Müller J, Schwedhelm E, Böger RH, Vasan RS. Plasma Nitrate and Incidence of Cardiovascular Disease and All-Cause Mortality in the Community: The Framingham Offspring Study. J Am Heart Assoc. 2017 11 18; 6(11).View Related Profiles.

Xanthakis, Vanessa
Ramachandran, Vasan

PMID: 29151027; PMCID: PMC5721741; DOI: 10.1161/JAHA.117.006224;

Staerk L, Wang B, Lunetta KL, Helm RH, Ko D, Sherer JA, Ellinor PT, Lubitz SA, McManus DD, Vasan RS, Benjamin EJ, Trinquart L. Association Between Leukocyte Telomere Length and the Risk of Incident Atrial Fibrillation: The Framingham Heart Study. J Am Heart Assoc. 2017 Nov 14; 6(11).View Related Profiles.

Wang, Biqi
Ko, Darae
Benjamin, Emelia
Sherer, Jason
Lunetta, Kathryn
Trinquart, Ludovic
Helm, Robert
Ramachandran, Vasan

PMID: 29138179; PMCID: PMC5721755; DOI: 10.1161/JAHA.117.006541;

McGrath ER, Beiser AS, DeCarli C, Plourde KL, Vasan RS, Greenberg SM, Seshadri S. Blood pressure from mid- to late life and risk of incident dementia. Neurology. 2017 Dec 12; 89(24):2447-2454.View Related Profiles.

Beiser, Alexa
Seshadri, Sudha
Ramachandran, Vasan

PMID: 29117954; PMCID: PMC5729797; DOI: 10.1212/WNL.0000000000004741;

Shah RV, Yeri AS, Murthy VL, Massaro JM, D'Agostino R, Freedman JE, Long MT, Fox CS, Das S, Benjamin EJ, Vasan RS, O'Donnell CJ, Hoffmann U. Association of Multiorgan Computed Tomographic Phenomap With Adverse Cardiovascular Health Outcomes: The Framingham Heart Study. JAMA Cardiol. 2017 11 01; 2(11):1236-1246.View Related Profiles.

O'Donnell, Christopher
Benjamin, Emelia
Long, Michelle
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 28975197; PMCID: PMC5710362; DOI: 10.1001/jamacardio.2017.3145;

O'Sullivan JF, Morningstar JE, Yang Q, Zheng B, Gao Y, Jeanfavre S, Scott J, Fernandez C, Zheng H, O'Connor S, Cohen P, Vasan RS, Long MT, Wilson JG, Melander O, Wang TJ, Fox C, Peterson RT, Clish CB, Corey KE, Gerszten RE. Dimethylguanidino valeric acid is a marker of liver fat and predicts diabetes. J Clin Invest. 2017 12 01; 127(12):4394-4402.View Related Profiles.

Long, Michelle
Yang, Qiong
Ramachandran, Vasan

PMID: 29083323; PMCID: PMC5707166; DOI: 10.1172/JCI95995;

Brody JA, Morrison AC, Bis JC, O'Connell JR, Brown MR, Huffman JE, Ames DC, Carroll A, Conomos MP, Gabriel S, Gibbs RA, Gogarten SM, Gupta N, Jaquish CE, Johnson AD, Lewis JP, Liu X, Manning AK, Papanicolaou GJ, Pitsillides AN, Rice KM, Salerno W, Sitlani CM, Smith NL, Heckbert SR, Laurie CC, Mitchell BD, Vasan RS, Rich SS, Rotter JI, Wilson JG, Boerwinkle E, Psaty BM, Cupples LA. Analysis commons, a team approach to discovery in a big-data environment for genetic epidemiology. Nat Genet. 2017 10 27; 49(11):1560-1563.View Related Profiles.

Cupples, L
Ramachandran, Vasan

PMID: 29074945; PMCID: PMC5720686; DOI: 10.1038/ng.3968;

Zakharov MN, Bhasin S, Travison TG, Xue R, Ulloor J, Ramachandran V, Carter E, Wu F, Jasuja R. Corrigendum to "A multi-step, allosteric model of testosterone's binding to sex hormone binding globulin" [Mol. Cell. Endocrinol. 399 (2015) 190-200]. Mol Cell Endocrinol. 2017 10 15; 454:167.View Related Profiles.

Ulloor, Jagadish
Zakharov, Mikhail
Ramachandran, Vasan

PMID: 28780939

Andersson C, Vasan RS. Epidemiology of cardiovascular disease in young individuals. Nat Rev Cardiol. 2018 04; 15(4):230-240. PMID: 29022571; DOI: 10.1038/nrcardio.2017.154;

Fetterman JL, Liu C, Mitchell GF, Vasan RS, Benjamin EJ, Vita JA, Hamburg NM, Levy D. Relations of mitochondrial genetic variants to measures of vascular function. Mitochondrion. 2018 05; 40:51-57.View Related Profiles.

Liu, Chunyu
Levy, Daniel
Benjamin, Emelia
Fetterman, Jessica
Hamburg, Naomi
Ramachandran, Vasan

PMID: 28993255; PMCID: PMC5858959; DOI: 10.1016/j.mito.2017.10.001;

Vasan RS, Xanthakis V, Lyass A, Andersson C, Tsao C, Cheng S, Aragam J, Benjamin EJ, Larson MG. Epidemiology of Left Ventricular Systolic Dysfunction and Heart Failure in the Framingham Study: An Echocardiographic Study Over 3 Decades. JACC Cardiovasc Imaging. 2018 01; 11(1):1-11.View Related Profiles.

Benjamin, Emelia
Aragam, Jayashri
Larson, Martin
Xanthakis, Vanessa
Ramachandran, Vasan

PMID: 28917679; PMCID: PMC5756128; DOI: 10.1016/j.jcmg.2017.08.007;

Delling FN, Li X, Li S, Yang Q, Xanthakis V, Martinsson A, Andell P, Lehman BT, Osypiuk EW, Stantchev P, Zöller B, Benjamin EJ, Sundquist K, Vasan RS, Smith JG. Heritability of Mitral Regurgitation: Observations From the Framingham Heart Study and Swedish Population. Circ Cardiovasc Genet. 2017 Oct; 10(5).View Related Profiles.

Benjamin, Emelia
Osypiuk, Ewa
Yang, Qiong
Xanthakis, Vanessa
Ramachandran, Vasan

PMID: 28993406; PMCID: PMC5679298; DOI: 10.1161/CIRCGENETICS.117.001736;

Niiranen TJ, Larson MG, McCabe EL, Xanthakis V, Vasan RS, Cheng S. Prognosis of Prehypertension Without Progression to Hypertension. Circulation. 2017 09 26; 136(13):1262-1264.View Related Profiles.

Larson, Martin
Xanthakis, Vanessa
Ramachandran, Vasan

PMID: 28947482; PMCID: PMC5658013; DOI: 10.1161/CIRCULATIONAHA.117.029317;

Cooper LL, Himali JJ, Torjesen A, Tsao CW, Beiser A, Hamburg NM, DeCarli C, Vasan RS, Seshadri S, Pase MP, Mitchell GF. Inter-Relations of Orthostatic Blood Pressure Change, Aortic Stiffness, and Brain Structure and Function in Young Adults. J Am Heart Assoc. 2017 Aug 17; 6(8).View Related Profiles.

Beiser, Alexa
Himali, Jayandra
Hamburg, Naomi
Seshadri, Sudha
Ramachandran, Vasan

PMID: 28862943; PMCID: PMC5586458; DOI: 10.1161/JAHA.117.006206;

Jasuja GK, Travison TG, Murabito JM, Davda MN, Rose AJ, Basaria S, Coviello A, Vasan RS, D'Agostino R, Bhasin S. Circulating Estrogen Levels and Self-Reported Health and Mobility Limitation in Community-Dwelling Men of the Framingham Heart Study. J Gerontol A Biol Sci Med Sci. 2017 Aug 01; 72(8):1137-1142.View Related Profiles.

Rose, Adam
Jasuja, Guneet
Murabito, Joanne
D'Agostino, Ralph
Bhasin, Shalender
Ramachandran, Vasan

PMID: 28329787; PMCID: PMC5861927; DOI: 10.1093/gerona/glw197;

Niiranen TJ, McCabe EL, Larson MG, Henglin M, Lakdawala NK, Vasan RS, Cheng S. Risk for hypertension crosses generations in the community: a multi-generational cohort study. Eur Heart J. 2017 Aug 01; 38(29):2300-2308.View Related Profiles.

Larson, Martin
Lakdawala, Neal
Ramachandran, Vasan

PMID: 28430902; PMCID: PMC6075041; DOI: 10.1093/eurheartj/ehx134;

Kent ST, Rosenson RS, Avery CL, Chen YI, Correa A, Cummings SR, Cupples LA, Cushman M, Evans DS, Gudnason V, Harris TB, Howard G, Irvin MR, Judd SE, Jukema JW, Lange L, Levitan EB, Li X, Liu Y, Post WS, Postmus I, Psaty BM, Rotter JI, Safford MM, Sitlani CM, Smith AV, Stewart JD, Trompet S, Sun F, Vasan RS, Woolley JM, Whitsel EA, Wiggins KL, Wilson JG, Muntner P. PCSK9 Loss-of-Function Variants, Low-Density Lipoprotein Cholesterol, and Risk of Coronary Heart Disease and Stroke: Data From 9 Studies of Blacks and Whites. Circ Cardiovasc Genet. 2017 Aug; 10(4):e001632.View Related Profiles.

Cupples, L
Ramachandran, Vasan

PMID: 28768753; PMCID: PMC5729040; DOI: 10.1161/CIRCGENETICS.116.001632;

Li W, Dorans KS, Wilker EH, Rice MB, Ljungman PL, Schwartz JD, Coull BA, Koutrakis P, Gold DR, Keaney JF, Vasan RS, Benjamin EJ, Mittleman MA. Short-Term Exposure to Ambient Air Pollution and Biomarkers of Systemic Inflammation: The Framingham Heart Study. Arterioscler Thromb Vasc Biol. 2017 Sep; 37(9):1793-1800.View Related Profiles.

Benjamin, Emelia
Ramachandran, Vasan

PMID: 28751572; PMCID: PMC5570664; DOI: 10.1161/ATVBAHA.117.309799;

Sardana M, Nah G, Tsao CW, Ogunsua AA, Vittinghoff E, Thomas RC, Cheng S, Vaze A, Aragam JR, Mitchell GF, Benjamin EJ, Vasan RS, Aurigemma GP, Schiller NB, McManus DD, Parikh NI. Clinical and Echocardiographic Correlates of Left Atrial Function Index: The Framingham Offspring Study. J Am Soc Echocardiogr. 2017 Sep; 30(9):904-912.e2.View Related Profiles.

Benjamin, Emelia
Aragam, Jayashri
Ramachandran, Vasan

PMID: 28735892; PMCID: PMC6298216; DOI: 10.1016/j.echo.2017.05.013;

Seyerle AA, Sitlani CM, Noordam R, Gogarten SM, Li J, Li X, Evans DS, Sun F, Laaksonen MA, Isaacs A, Kristiansson K, Highland HM, Stewart JD, Harris TB, Trompet S, Bis JC, Peloso GM, Brody JA, Broer L, Busch EL, Duan Q, Stilp AM, O'Donnell CJ, Macfarlane PW, Floyd JS, Kors JA, Lin HJ, Li-Gao R, Sofer T, Méndez-Giráldez R, Cummings SR, Heckbert SR, Hofman A, Ford I, Li Y, Launer LJ, Porthan K, Newton-Cheh C, Napier MD, Kerr KF, Reiner AP, Rice KM, Roach J, Buckley BM, Soliman EZ, de Mutsert R, Sotoodehnia N, Uitterlinden AG, North KE, Lee CR, Gudnason V, Stürmer T, Rosendaal FR, Taylor KD, Wiggins KL, Wilson JG, Chen YD, Kaplan RC, Wilhelmsen K, Cupples LA, Salomaa V, van Duijn C, Jukema JW, Liu Y, Mook-Kanamori DO, Lange LA, Vasan RS, Smith AV, Stricker BH, Laurie CC, Rotter JI, Whitsel EA, Psaty BM, Avery CL. Pharmacogenomics study of thiazide diuretics and QT interval in multi-ethnic populations: the cohorts for heart and aging research in genomic epidemiology. Pharmacogenomics J. 2018 04; 18(2):215-226.View Related Profiles.

O'Donnell, Christopher
Peloso, Gina
Cupples, L
Ramachandran, Vasan

PMID: 28719597; PMCID: PMC5773415; DOI: 10.1038/tpj.2017.10;

Zachariah JP, Quiroz R, Enserro D, Andersson C, Keaney JF, Sullivan LM, Vasan RS. Association of Parental Obesity and Diabetes Mellitus With Circulating Adipokines in Nonobese Nondiabetic Offspring. J Am Heart Assoc. 2017 Jul 16; 6(7).View Related Profiles.

Sullivan, Lisa
Ramachandran, Vasan

PMID: 28713075; PMCID: PMC5586263; DOI: 10.1161/JAHA.116.004973;

Zachariah JP, Quiroz R, Nelson KP, Teng Z, Keaney JF, Sullivan LM, Vasan RS. Prospective Relation of Circulating Adipokines to Incident Metabolic Syndrome: The Framingham Heart Study. J Am Heart Assoc. 2017 Jul 16; 6(7).View Related Profiles.

Nelson, Kerrie
Sullivan, Lisa
Ramachandran, Vasan

PMID: 28713076; PMCID: PMC5586264; DOI: 10.1161/JAHA.116.004974;

Wheelock KM, Cai J, Looker HC, Merchant ML, Nelson RG, Fufaa GD, Weil EJ, Feldman HI, Vasan RS, Kimmel PL, Rovin BH, Mauer M, Klein JB. Plasma bradykinin and early diabetic nephropathy lesions in type 1 diabetes mellitus. PLoS One. 2017; 12(7):e0180964. PMID: 28700653; PMCID: PMC5507314; DOI: 10.1371/journal.pone.0180964;

Aparicio HJ, Himali JJ, Beiser AS, Davis-Plourde KL, Vasan RS, Kase CS, Wolf PA, Seshadri S. Overweight, Obesity, and Survival After Stroke in the Framingham Heart Study. J Am Heart Assoc. 2017 Jun 24; 6(6).View Related Profiles.

Beiser, Alexa
Kase, Carlos
Aparicio, Hugo
Himali, Jayandra
Wolf, Philip
Seshadri, Sudha
Ramachandran, Vasan

PMID: 28647687; PMCID: PMC5669145; DOI: 10.1161/JAHA.116.004721;

Rebholz CM, Inker LA, Chen Y, Liang M, Foster MC, Eckfeldt JH, Kimmel PL, Vasan RS, Feldman HI, Sarnak MJ, Hsu CY, Levey AS, Coresh J. Risk of ESRD and Mortality Associated With Change in Filtration Markers. Am J Kidney Dis. 2017 Oct; 70(4):551-560. PMID: 28648303; PMCID: PMC5610931; DOI: 10.1053/j.ajkd.2017.04.025;

Aparicio HJ, Petrea RE, Massaro JM, Manning WJ, Oyama-Manabe N, Beiser AS, Kase CS, D'Agostino RB, Wolf PA, Vasan RS, DeCarli C, O'Donnell CJ, Seshadri S. Association of descending thoracic aortic plaque with brain atrophy and white matter hyperintensities: The Framingham Heart Study. Atherosclerosis. 2017 Oct; 265:305-311.View Related Profiles.

Beiser, Alexa
Kase, Carlos
O'Donnell, Christopher
Aparicio, Hugo
Massaro, Joseph
Wolf, Philip
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Petrea, Rodica
Seshadri, Sudha
Ramachandran, Vasan

PMID: 28673480; PMCID: PMC5617776; DOI: 10.1016/j.atherosclerosis.2017.06.919;

Saber H, Himali JJ, Beiser AS, Shoamanesh A, Pikula A, Roubenoff R, Romero JR, Kase CS, Vasan RS, Seshadri S. Serum Insulin-Like Growth Factor 1 and the Risk of Ischemic Stroke: The Framingham Study. Stroke. 2017 Jul; 48(7):1760-1765.View Related Profiles.

Beiser, Alexa
Kase, Carlos
Himali, Jayandra
Romero, Jose
Seshadri, Sudha
Ramachandran, Vasan

PMID: 28596451; PMCID: PMC5505338; DOI: 10.1161/STROKEAHA.116.016563;

Chouraki V, Preis SR, Yang Q, Beiser A, Li S, Larson MG, Weinstein G, Wang TJ, Gerszten RE, Vasan RS, Seshadri S. Association of amine biomarkers with incident dementia and Alzheimer's disease in the Framingham Study. Alzheimers Dement. 2017 Dec; 13(12):1327-1336.View Related Profiles.

Beiser, Alexa
Weinstein, Galit
Larson, Martin
Yang, Qiong
Preis, Sarah
Seshadri, Sudha
Ramachandran, Vasan

PMID: 28602601; PMCID: PMC5722716; DOI: 10.1016/j.jalz.2017.04.009;

Tan ZS, Spartano NL, Beiser AS, DeCarli C, Auerbach SH, Vasan RS, Seshadri S. Physical Activity, Brain Volume, and Dementia Risk: The Framingham Study. J Gerontol A Biol Sci Med Sci. 2017 Jun 01; 72(6):789-795.View Related Profiles.

Beiser, Alexa
Spartano, Nicole
Auerbach, Sanford
Seshadri, Sudha
Ramachandran, Vasan

PMID: 27422439; PMCID: PMC6075525; DOI: 10.1093/gerona/glw130;

Jensen MK, Jensen RA, Mukamal KJ, Guo X, Yao J, Sun Q, Cornelis M, Liu Y, Chen MH, Kizer JR, Djoussé L, Siscovick DS, Psaty BM, Zmuda JM, Rotter JI, Garcia M, Harris T, Chen I, Goodarzi MO, Nalls MA, Keller M, Arnold AM, Newman AB, Hoogeveen RC, Rexrode KM, Rimm EB, Hu FB, Ramachandran VS, Katz R, Pankow JS, Ix JH. Detection of genetic loci associated with plasma fetuin-A: a meta-analysis of genome-wide association studies from the CHARGE Consortium. Hum Mol Genet. 2017 Jun 01; 26(11):2156-2163. PMID: 28379451; PMCID: PMC6075215; DOI: 10.1093/hmg/ddx091;

Niiranen TJ, Lyass A, Larson MG, Hamburg NM, Benjamin EJ, Mitchell GF, Vasan RS. Prevalence, Correlates, and Prognosis of Healthy Vascular Aging in a Western Community-Dwelling Cohort: The Framingham Heart Study. Hypertension. 2017 Aug; 70(2):267-274.View Related Profiles.

Benjamin, Emelia
Larson, Martin
Hamburg, Naomi
Ramachandran, Vasan

PMID: 28559398; PMCID: PMC5509504; DOI: 10.1161/HYPERTENSIONAHA.117.09026;

Tragante V, Gho JMIH, Felix JF, Vasan RS, Smith NL, Voight BF, Palmer C, van der Harst P, Moore JH, Asselbergs FW. Gene Set Enrichment Analyses: lessons learned from the heart failure phenotype. BioData Min. 2017; 10:18. PMID: 28559929; PMCID: PMC5446754; DOI: 10.1186/s13040-017-0137-5;

Niiranen TJ, McCabe EL, Larson MG, Henglin M, Lakdawala NK, Vasan RS, Cheng S. Heritability and risks associated with early onset hypertension: multigenerational, prospective analysis in the Framingham Heart Study. BMJ. 2017 May 12; 357:j1949.View Related Profiles.

Larson, Martin
Lakdawala, Neal
Ramachandran, Vasan

PMID: 28500036; PMCID: PMC5430541; DOI: 10.1136/bmj.j1949;

Niu J, Clancy M, Aliabadi P, Vasan R, Felson DT. Metabolic Syndrome, Its Components, and Knee Osteoarthritis: The Framingham Osteoarthritis Study. Arthritis Rheumatol. 2017 Jun; 69(6):1194-1203.View Related Profiles.

Felson, David
Niu, Jingbo
Ramachandran, Vasan

PMID: 28257604; PMCID: PMC5449217; DOI: 10.1002/art.40087;

Maillard P, Mitchell GF, Himali JJ, Beiser A, Fletcher E, Tsao CW, Pase MP, Satizabal CL, Vasan RS, Seshadri S, DeCarli C. Aortic Stiffness, Increased White Matter Free Water, and Altered Microstructural Integrity: A Continuum of Injury. Stroke. 2017 Jun; 48(6):1567-1573.View Related Profiles.

Beiser, Alexa
Satizabal, Claudia
Himali, Jayandra
Seshadri, Sudha
Ramachandran, Vasan

PMID: 28473633; PMCID: PMC5502744; DOI: 10.1161/STROKEAHA.116.016321;

Ho JE, McCabe EL, Wang TJ, Larson MG, Levy D, Tsao C, Aragam J, Mitchell GF, Benjamin EJ, Vasan RS, Cheng S. Cardiometabolic Traits and Systolic Mechanics in the Community. Circ Heart Fail. 2017 May; 10(5).View Related Profiles.

Levy, Daniel
Benjamin, Emelia
Aragam, Jayashri
Larson, Martin
Ramachandran, Vasan

PMID: 28495953; PMCID: PMC5500189; DOI: 10.1161/CIRCHEARTFAILURE.116.003536;

Freiberg MS, Chang CH, Skanderson M, Patterson OV, DuVall SL, Brandt CA, So-Armah KA, Vasan RS, Oursler KA, Gottdiener J, Gottlieb S, Leaf D, Rodriguez-Barradas M, Tracy RP, Gibert CL, Rimland D, Bedimo RJ, Brown ST, Goetz MB, Warner A, Crothers K, Tindle HA, Alcorn C, Bachmann JM, Justice AC, Butt AA. Association Between HIV Infection and the Risk of Heart Failure With Reduced Ejection Fraction and Preserved Ejection Fraction in the Antiretroviral Therapy Era: Results From the Veterans Aging Cohort Study. JAMA Cardiol. 2017 05 01; 2(5):536-546.View Related Profiles.

So-Armah, Kaku
Ramachandran, Vasan

PMID: 28384660; PMCID: PMC5541383; DOI: 10.1001/jamacardio.2017.0264;

Pase MP, Himali JJ, Beiser AS, Aparicio HJ, Satizabal CL, Vasan RS, Seshadri S, Jacques PF. Sugar- and Artificially Sweetened Beverages and the Risks of Incident Stroke and Dementia: A Prospective Cohort Study. Stroke. 2017 May; 48(5):1139-1146.View Related Profiles.

Beiser, Alexa
Satizabal, Claudia
Aparicio, Hugo
Himali, Jayandra
Seshadri, Sudha
Ramachandran, Vasan

PMID: 28428346; PMCID: PMC5405737; DOI: 10.1161/STROKEAHA.116.016027;

Wild PS, Felix JF, Schillert A, Teumer A, Chen MH, Leening MJG, Völker U, Großmann V, Brody JA, Irvin MR, Shah SJ, Pramana S, Lieb W, Schmidt R, Stanton AV, Malzahn D, Smith AV, Sundström J, Minelli C, Ruggiero D, Lyytikäinen LP, Tiller D, Smith JG, Monnereau C, Di Tullio MR, Musani SK, Morrison AC, Pers TH, Morley M, Kleber ME, Aragam J, Benjamin EJ, Bis JC, Bisping E, Broeckel U, Cheng S, Deckers JW, Del Greco M F, Edelmann F, Fornage M, Franke L, Friedrich N, Harris TB, Hofer E, Hofman A, Huang J, Hughes AD, Kähönen M, Investigators K, Kruppa J, Lackner KJ, Lannfelt L, Laskowski R, Launer LJ, Leosdottir M, Lin H, Lindgren CM, Loley C, MacRae CA, Mascalzoni D, Mayet J, Medenwald D, Morris AP, Müller C, Müller-Nurasyid M, Nappo S, Nilsson PM, Nuding S, Nutile T, Peters A, Pfeufer A, Pietzner D, Pramstaller PP, Raitakari OT, Rice KM, Rivadeneira F, Rotter JI, Ruohonen ST, Sacco RL, Samdarshi TE, Schmidt H, Sharp ASP, Shields DC, Sorice R, Sotoodehnia N, Stricker BH, Surendran P, Thom S, Töglhofer AM, Uitterlinden AG, Wachter R, Völzke H, Ziegler A, Münzel T, März W, Cappola TP, Hirschhorn JN, Mitchell GF, Smith NL, Fox ER, Dueker ND, Jaddoe VWV, Melander O, Russ M, Lehtimäki T, Ciullo M, Hicks AA, Lind L, Gudnason V, Pieske B, Barron AJ, Zweiker R, Schunkert H, Ingelsson E, Liu K, Arnett DK, Psaty BM, Blankenberg S, Larson MG, Felix SB, Franco OH, Zeller T, Vasan RS, Dörr M. Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function. J Clin Invest. 2017 May 01; 127(5):1798-1812.View Related Profiles.

Benjamin, Emelia
Lin, Honghuang
Aragam, Jayashri
Larson, Martin
Ramachandran, Vasan

PMID: 28394258; PMCID: PMC5409098; DOI: 10.1172/JCI84840;

Niiranen TJ, Kalesan B, Larson MG, Hamburg NM, Benjamin EJ, Mitchell GF, Vasan RS. Aortic-Brachial Arterial Stiffness Gradient and Cardiovascular Risk in the Community: The Framingham Heart Study. Hypertension. 2017 Jun; 69(6):1022-1028.View Related Profiles.

Kalesan, Bindu
Benjamin, Emelia
Larson, Martin
Hamburg, Naomi
Ramachandran, Vasan

PMID: 28396534; PMCID: PMC5426958; DOI: 10.1161/HYPERTENSIONAHA.116.08917;

Warren CR, O'Sullivan JF, Friesen M, Becker CE, Zhang X, Liu P, Wakabayashi Y, Morningstar JE, Shi X, Choi J, Xia F, Peters DT, Florido MH, Tsankov AM, Duberow E, Comisar L, Shay J, Jiang X, Meissner A, Musunuru K, Kathiresan S, Daheron L, Zhu J, Gerszten RE, Deo RC, Vasan RS, O'Donnell CJ, Cowan CA. Induced Pluripotent Stem Cell Differentiation Enables Functional Validation of GWAS Variants in Metabolic Disease. Cell Stem Cell. 2017 Apr 06; 20(4):547-557.e7.View Related Profiles.

O'Donnell, Christopher
Choi, Jihoon
Ramachandran, Vasan
Zhang, Xiaoling

PMID: 28388431; DOI: 10.1016/j.stem.2017.01.010;

Torjesen A, Cooper LL, Rong J, Larson MG, Hamburg NM, Levy D, Benjamin EJ, Vasan RS, Mitchell GF. Relations of Arterial Stiffness With Postural Change in Mean Arterial Pressure in Middle-Aged Adults: The Framingham Heart Study. Hypertension. 2017 Apr; 69(4):685-690.View Related Profiles.

Levy, Daniel
Benjamin, Emelia
Rong, Jian
Larson, Martin
Hamburg, Naomi
Ramachandran, Vasan

PMID: 28264924; PMCID: PMC5382873; DOI: 10.1161/HYPERTENSIONAHA.116.08116;

Tripathi A, Benjamin EJ, Musani SK, Hamburg NM, Tsao CW, Saraswat A, Vasan RS, Mitchell GF, Fox ER. The association of endothelial function and tone by digital arterial tonometry with MRI left ventricular mass in African Americans: the Jackson Heart Study. J Am Soc Hypertens. 2017 May; 11(5):258-264.View Related Profiles.

Benjamin, Emelia
Hamburg, Naomi
Ramachandran, Vasan

PMID: 28412277; DOI: 10.1016/j.jash.2017.03.005;

Brant LC, Wang N, Ojeda FM, LaValley M, Barreto SM, Benjamin EJ, Mitchell GF, Vasan RS, Palmisano JN, Münzel T, Blankenberg S, Wild PS, Zeller T, Ribeiro AL, Schnabel RB, Hamburg NM. Relations of Metabolically Healthy and Unhealthy Obesity to Digital Vascular Function in Three Community-Based Cohorts: A Meta-Analysis. J Am Heart Assoc. 2017 Mar 08; 6(3).View Related Profiles.

Benjamin, Emelia
LaValley, Michael
Hamburg, Naomi
Ramachandran, Vasan

PMID: 28275071; PMCID: PMC5523995; DOI: 10.1161/JAHA.116.004199;

Pase MP, Himali JJ, Jacques PF, DeCarli C, Satizabal CL, Aparicio H, Vasan RS, Beiser AS, Seshadri S. Sugary beverage intake and preclinical Alzheimer's disease in the community. Alzheimers Dement. 2017 Sep; 13(9):955-964.View Related Profiles.

Beiser, Alexa
Satizabal, Claudia
Aparicio, Hugo
Himali, Jayandra
Seshadri, Sudha
Ramachandran, Vasan

PMID: 28274718; PMCID: PMC6820519; DOI: 10.1016/j.jalz.2017.01.024;

Park M, Hsu CY, Go AS, Feldman HI, Xie D, Zhang X, Mifflin T, Waikar SS, Sabbisetti VS, Bonventre JV, Coresh J, Nelson RG, Kimmel PL, Kusek JW, Rahman M, Schelling JR, Vasan RS, Liu KD. Urine Kidney Injury Biomarkers and Risks of Cardiovascular Disease Events and All-Cause Death: The CRIC Study. Clin J Am Soc Nephrol. 2017 May 08; 12(5):761-771.View Related Profiles.

Waikar, Sushrut
Ramachandran, Vasan

PMID: 28254771; PMCID: PMC5477212; DOI: 10.2215/CJN.08560816;

Nayor M, Larson MG, Wang N, Santhanakrishnan R, Lee DS, Tsao CW, Cheng S, Benjamin EJ, Vasan RS, Levy D, Fox CS, Ho JE. The association of chronic kidney disease and microalbuminuria with heart failure with preserved vs. reduced ejection fraction. Eur J Heart Fail. 2017 May; 19(5):615-623.View Related Profiles.

Benjamin, Emelia
Larson, Martin
Nayor, Matthew
Ramachandran, Vasan

PMID: 28217978; PMCID: PMC5423843; DOI: 10.1002/ejhf.778;

Christiansen MN, Køber L, Weeke P, Vasan RS, Jeppesen JL, Smith JG, Gislason GH, Torp-Pedersen C, Andersson C. Age-Specific Trends in Incidence, Mortality, and Comorbidities of Heart Failure in Denmark, 1995 to 2012. Circulation. 2017 Mar 28; 135(13):1214-1223. PMID: 28174193; DOI: 10.1161/CIRCULATIONAHA.116.025941;

Dufouil C, Beiser A, McLure LA, Wolf PA, Tzourio C, Howard VJ, Westwood AJ, Himali JJ, Sullivan L, Aparicio HJ, Kelly-Hayes M, Ritchie K, Kase CS, Pikula A, Romero JR, D'Agostino RB, Samieri C, Vasan RS, Chêne G, Howard G, Seshadri S. Revised Framingham Stroke Risk Profile to Reflect Temporal Trends. Circulation. 2017 Mar 21; 135(12):1145-1159.View Related Profiles.

Beiser, Alexa
Kase, Carlos
Aparicio, Hugo
Himali, Jayandra
Romero, Jose
Sullivan, Lisa
Wolf, Philip
D'Agostino, Ralph
Seshadri, Sudha
Ramachandran, Vasan

PMID: 28159800; PMCID: PMC5504355; DOI: 10.1161/CIRCULATIONAHA.115.021275;

Romero JR, Preis SR, Beiser A, Himali JJ, Shoamanesh A, Wolf PA, Kase CS, Vasan RS, DeCarli C, Seshadri S. Cerebral Microbleeds as Predictors of Mortality: The Framingham Heart Study. Stroke. 2017 Mar; 48(3):781-783.View Related Profiles.

Beiser, Alexa
Shoamanesh, Ashkan
Kase, Carlos
Himali, Jayandra
Romero, Jose
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Preis, Sarah
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Ramachandran, Vasan

PMID: 28143923; PMCID: PMC5330856; DOI: 10.1161/STROKEAHA.116.015354;

Parikh NI, Norberg M, Ingelsson E, Cnattingius S, Vasan RS, Domellöf M, Jansson JH, Edstedt Bonamy AK. Association of Pregnancy Complications and Characteristics With Future Risk of Elevated Blood Pressure: The Västerbotten Intervention Program. Hypertension. 2017 Mar; 69(3):475-483. PMID: 28137991; PMCID: PMC5604339; DOI: 10.1161/HYPERTENSIONAHA.116.08121;

Spartano NL, Stevenson MD, Xanthakis V, Larson MG, Andersson C, Murabito JM, Vasan RS. Associations of objective physical activity with insulin sensitivity and circulating adipokine profile: the Framingham Heart Study. Clin Obes. 2017 Apr; 7(2):59-69.View Related Profiles.

Murabito, Joanne
Larson, Martin
Spartano, Nicole
Xanthakis, Vanessa
Ramachandran, Vasan

PMID: 28112860; PMCID: PMC5339058; DOI: 10.1111/cob.12177;

Bell V, McCabe EL, Larson MG, Rong J, Merz AA, Osypiuk E, Lehman BT, Stantchev P, Aragam J, Benjamin EJ, Hamburg NM, Vasan RS, Mitchell GF, Cheng S. Relations Between Aortic Stiffness and Left Ventricular Mechanical Function in the Community. J Am Heart Assoc. 2017 Jan 09; 6(1).View Related Profiles.

Benjamin, Emelia
Osypiuk, Ewa
Aragam, Jayashri
Larson, Martin
Hamburg, Naomi
Ramachandran, Vasan

PMID: 28069573; PMCID: PMC5523643; DOI: 10.1161/JAHA.116.004903;

Weinstein G, Preis SR, Beiser AS, Kaess B, Chen TC, Satizabal C, Rahman F, Benjamin EJ, Vasan RS, Seshadri S. Clinical and Environmental Correlates of Serum BDNF: A Descriptive Study with Plausible Implications for AD Research. Curr Alzheimer Res. 2017; 14(7):722-730.View Related Profiles.

Beiser, Alexa
Satizabal, Claudia
Benjamin, Emelia
Weinstein, Galit
Preis, Sarah
Seshadri, Sudha
Ramachandran, Vasan

PMID: 28164772; PMCID: PMC6026027; DOI: 10.2174/1567205014666170203094520;

Noordam R, Sitlani CM, Avery CL, Stewart JD, Gogarten SM, Wiggins KL, Trompet S, Warren HR, Sun F, Evans DS, Li X, Li J, Smith AV, Bis JC, Brody JA, Busch EL, Caulfield MJ, Chen YI, Cummings SR, Cupples LA, Duan Q, Franco OH, Méndez-Giráldez R, Harris TB, Heckbert SR, van Heemst D, Hofman A, Floyd JS, Kors JA, Launer LJ, Li Y, Li-Gao R, Lange LA, Lin HJ, de Mutsert R, Napier MD, Newton-Cheh C, Poulter N, Reiner AP, Rice KM, Roach J, Rodriguez CJ, Rosendaal FR, Sattar N, Sever P, Seyerle AA, Slagboom PE, Soliman EZ, Sotoodehnia N, Stott DJ, Stürmer T, Taylor KD, Thornton TA, Uitterlinden AG, Wilhelmsen KC, Wilson JG, Gudnason V, Jukema JW, Laurie CC, Liu Y, Mook-Kanamori DO, Munroe PB, Rotter JI, Vasan RS, Psaty BM, Stricker BH, Whitsel EA. A genome-wide interaction analysis of tricyclic/tetracyclic antidepressants and RR and QT intervals: a pharmacogenomics study from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium. J Med Genet. 2017 May; 54(5):313-323.View Related Profiles.

Sun, Fangui
Cupples, L
Ramachandran, Vasan

PMID: 28039329; PMCID: PMC5406254; DOI: 10.1136/jmedgenet-2016-104112;

Emdin CA, Khera AV, Natarajan P, Klarin D, Won HH, Peloso GM, Stitziel NO, Nomura A, Zekavat SM, Bick AG, Gupta N, Asselta R, Duga S, Merlini PA, Correa A, Kessler T, Wilson JG, Bown MJ, Hall AS, Braund PS, Samani NJ, Schunkert H, Marrugat J, Elosua R, McPherson R, Farrall M, Watkins H, Willer C, Abecasis GR, Felix JF, Vasan RS, Lander E, Rader DJ, Danesh J, Ardissino D, Gabriel S, Saleheen D, Kathiresan S. Phenotypic Characterization of Genetically Lowered Human Lipoprotein(a) Levels. J Am Coll Cardiol. 2016 Dec 27; 68(25):2761-2772.View Related Profiles.

Peloso, Gina
Ramachandran, Vasan

PMID: 28007139; PMCID: PMC5328146; DOI: 10.1016/j.jacc.2016.10.033;

Chatterjee R, Davenport CA, Svetkey LP, Batch BC, Lin PH, Ramachandran VS, Fox ER, Harman J, Yeh HC, Selvin E, Correa A, Butler K, Edelman D. Serum potassium is a predictor of incident diabetes in African Americans with normal aldosterone: the Jackson Heart Study. Am J Clin Nutr. 2017 Feb; 105(2):442-449. PMID: 27974310; PMCID: PMC5267306; DOI: 10.3945/ajcn.116.143255;

Li M, Li Y, Weeks O, Mijatovic V, Teumer A, Huffman JE, Tromp G, Fuchsberger C, Gorski M, Lyytikäinen LP, Nutile T, Sedaghat S, Sorice R, Tin A, Yang Q, Ahluwalia TS, Arking DE, Bihlmeyer NA, Böger CA, Carroll RJ, Chasman DI, Cornelis MC, Dehghan A, Faul JD, Feitosa MF, Gambaro G, Gasparini P, Giulianini F, Heid I, Huang J, Imboden M, Jackson AU, Jeff J, Jhun MA, Katz R, Kifley A, Kilpeläinen TO, Kumar A, Laakso M, Li-Gao R, Lohman K, Lu Y, Mägi R, Malerba G, Mihailov E, Mohlke KL, Mook-Kanamori DO, Robino A, Ruderfer D, Salvi E, Schick UM, Schulz CA, Smith AV, Smith JA, Traglia M, Yerges-Armstrong LM, Zhao W, Goodarzi MO, Kraja AT, Liu C, Wessel J, Boerwinkle E, Borecki IB, Bork-Jensen J, Bottinger EP, Braga D, Brandslund I, Brody JA, Campbell A, Carey DJ, Christensen C, Coresh J, Crook E, Curhan GC, Cusi D, de Boer IH, de Vries AP, Denny JC, Devuyst O, Dreisbach AW, Endlich K, Esko T, Franco OH, Fulop T, Gerhard GS, Glümer C, Gottesman O, Grarup N, Gudnason V, Hansen T, Harris TB, Hayward C, Hocking L, Hofman A, Hu FB, Husemoen LL, Jackson RD, Jørgensen T, Jørgensen ME, Kähönen M, Kardia SL, König W, Kooperberg C, Kriebel J, Launer LJ, Lauritzen T, Lehtimäki T, Levy D, Linksted P, Linneberg A, Liu Y, Loos RJ, Lupo A, Meisinger C, Melander O, Metspalu A, Mitchell P, Nauck M, Nürnberg P, Orho-Melander M, Parsa A, Pedersen O, Peters A, Peters U, Polasek O, Porteous D, Probst-Hensch NM, Psaty BM, Qi L, Raitakari OT, Reiner AP, Rettig R, Ridker PM, Rivadeneira F, Rossouw JE, Schmidt F, Siscovick D, Soranzo N, Strauch K, Toniolo D, Turner ST, Uitterlinden AG, Ulivi S, Velayutham D, Völker U, Völzke H, Waldenberger M, Wang JJ, Weir DR, Witte D, Kuivaniemi H, Fox CS, Franceschini N, Goessling W, Köttgen A, Chu AY. SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function. J Am Soc Nephrol. 2017 Mar; 28(3):981-994.View Related Profiles.

Liu, Chunyu
Cupples, L
Yang, Qiong
Ramachandran, Vasan

PMID: 27920155; PMCID: PMC5328154; DOI: 10.1681/ASN.2016020131;

Wang H, Cade BE, Chen H, Gleason KJ, Saxena R, Feng T, Larkin EK, Vasan RS, Lin H, Patel SR, Tracy RP, Liu Y, Gottlieb DJ, Below JE, Hanis CL, Petty LE, Sunyaev SR, Frazier-Wood AC, Rotter JI, Post W, Lin X, Redline S, Zhu X. Variants in angiopoietin-2 (ANGPT2) contribute to variation in nocturnal oxyhaemoglobin saturation level. Hum Mol Genet. 2016 Dec 01; 25(23):5244-5253.View Related Profiles.

Lin, Honghuang
Ramachandran, Vasan

PMID: 27798093; PMCID: PMC6078634; DOI: 10.1093/hmg/ddw324;

Cooper LL, Palmisano JN, Benjamin EJ, Larson MG, Vasan RS, Mitchell GF, Hamburg NM. Microvascular Function Contributes to the Relation Between Aortic Stiffness and Cardiovascular Events: The Framingham Heart Study. Circ Cardiovasc Imaging. 2016 Dec; 9(12).View Related Profiles.

Benjamin, Emelia
Larson, Martin
Hamburg, Naomi
Ramachandran, Vasan

PMID: 27956408; PMCID: PMC5557409; DOI: 10.1161/CIRCIMAGING.116.004979;

Mitchell GF, Hwang SJ, Larson MG, Hamburg NM, Benjamin EJ, Vasan RS, Levy D, Vita JA. Reply. J Hypertens. 2016 12; 34(12):2489-2490.View Related Profiles.

Levy, Daniel
Benjamin, Emelia
Larson, Martin
Hamburg, Naomi
Hwang, Shih-Jen
Ramachandran, Vasan

PMID: 27805916

Andersson C, Vasan RS. Intensive vs Standard Blood Pressure Control for Older Adults. JAMA. 2016 Nov 08; 316(18):1922-1923. PMID: 27825004; DOI: 10.1001/jama.2016.14927;

Bozkurt B, Colvin M, Cook J, Cooper LT, Deswal A, Fonarow GC, Francis GS, Lenihan D, Lewis EF, McNamara DM, Pahl E, Vasan RS, Ramasubbu K, Rasmusson K, Towbin JA, Yancy C. Current Diagnostic and Treatment Strategies for Specific Dilated Cardiomyopathies: A Scientific Statement From the American Heart Association. Circulation. 2016 12 06; 134(23):e579-e646. PMID: 27832612

Hsu CY, Xie D, Waikar SS, Bonventre JV, Zhang X, Sabbisetti V, Mifflin TE, Coresh J, Diamantidis CJ, He J, Lora CM, Miller ER, Nelson RG, Ojo AO, Rahman M, Schelling JR, Wilson FP, Kimmel PL, Feldman HI, Vasan RS, Liu KD. Urine biomarkers of tubular injury do not improve on the clinical model predicting chronic kidney disease progression. Kidney Int. 2017 Jan; 91(1):196-203.View Related Profiles.

Waikar, Sushrut
Ramachandran, Vasan

PMID: 28029431; PMCID: PMC5362331; DOI: 10.1016/j.kint.2016.09.003;

Bretón-Romero R, Wang N, Palmisano J, Larson MG, Vasan RS, Mitchell GF, Benjamin EJ, Vita JA, Hamburg NM. Cross-Sectional Associations of Flow Reversal, Vascular Function, and Arterial Stiffness in the Framingham Heart Study. Arterioscler Thromb Vasc Biol. 2016 Dec; 36(12):2452-2459.View Related Profiles.

Benjamin, Emelia
Larson, Martin
Hamburg, Naomi
Breton-Romero, Rosa
Ramachandran, Vasan

PMID: 27789476; PMCID: PMC5557404; DOI: 10.1161/ATVBAHA.116.307948;

Niiranen TJ, Kalesan B, Hamburg NM, Benjamin EJ, Mitchell GF, Vasan RS. Relative Contributions of Arterial Stiffness and Hypertension to Cardiovascular Disease: The Framingham Heart Study. J Am Heart Assoc. 2016 Oct 26; 5(11).View Related Profiles.

Kalesan, Bindu
Benjamin, Emelia
Hamburg, Naomi
Ramachandran, Vasan

PMID: 27912210; PMCID: PMC5210358; DOI: 10.1161/JAHA.116.004271;

Rahman F, Himali JJ, Yin X, Beiser AS, Ellinor PT, Lubitz SA, Vasan RS, Magnani JW, McManus DD, Seshadri S, Benjamin EJ. Serum brain-derived neurotrophic factor and risk of atrial fibrillation. Am Heart J. 2017 Jan; 183:69-73.View Related Profiles.

Beiser, Alexa
Benjamin, Emelia
Himali, Jayandra
Seshadri, Sudha
Ramachandran, Vasan

PMID: 27979044; PMCID: PMC5166602; DOI: 10.1016/j.ahj.2016.07.027;

Tsao CW, Vasan RS. Reply: Size Matters? Seeking High-Risk Populations Among "Normal" Individuals. JACC Heart Fail. 2016 10; 4(10):828-829. PMID: 27686927; DOI: 10.1016/j.jchf.2016.06.009;

Zhang W, Jernerén F, Lehne BC, Chen MH, Luben RN, Johnston C, Elshorbagy A, Eppinga RN, Scott WR, Adeyeye E, Scott J, Böger RH, Khaw KT, van der Harst P, Wareham NJ, Vasan RS, Chambers JC, Refsum H, Kooner JS. Genome-wide association reveals that common genetic variation in the kallikrein-kinin system is associated with serum L-arginine levels. Thromb Haemost. 2016 Nov 30; 116(6):1041-1049. PMID: 27656708; PMCID: PMC6215702; DOI: 10.1160/TH16-02-0151;

McManus DD, Yin X, Gladstone R, Vittinghoff E, Vasan RS, Larson MG, Benjamin EJ, Marcus GM. Alcohol Consumption, Left Atrial Diameter, and Atrial Fibrillation. J Am Heart Assoc. 2016 Sep 14; 5(9).View Related Profiles.

Benjamin, Emelia
Larson, Martin
Ramachandran, Vasan

PMID: 27628571; PMCID: PMC5079048; DOI: 10.1161/JAHA.116.004060;

Surendran P, Drenos F, Young R, Warren H, Cook JP, Manning AK, Grarup N, Sim X, Barnes DR, Witkowska K, Staley JR, Tragante V, Tukiainen T, Yaghootkar H, Masca N, Freitag DF, Ferreira T, Giannakopoulou O, Tinker A, Harakalova M, Mihailov E, Liu C, Kraja AT, Nielsen SF, Rasheed A, Samuel M, Zhao W, Bonnycastle LL, Jackson AU, Narisu N, Swift AJ, Southam L, Marten J, Huyghe JR, Stancáková A, Fava C, Ohlsson T, Matchan A, Stirrups KE, Bork-Jensen J, Gjesing AP, Kontto J, Perola M, Shaw-Hawkins S, Havulinna AS, Zhang H, Donnelly LA, Groves CJ, Rayner NW, Neville MJ, Robertson NR, Yiorkas AM, Herzig KH, Kajantie E, Zhang W, Willems SM, Lannfelt L, Malerba G, Soranzo N, Trabetti E, Verweij N, Evangelou E, Moayyeri A, Vergnaud AC, Nelson CP, Poveda A, Varga TV, Caslake M, de Craen AJ, Trompet S, Luan J, Scott RA, Harris SE, Liewald DC, Marioni R, Menni C, Farmaki AE, Hallmans G, Renström F, Huffman JE, Hassinen M, Burgess S, Vasan RS, Felix JF, Uria-Nickelsen M, Malarstig A, Reilly DF, Hoek M, Vogt TF, Lin H, Lieb W, Traylor M, Markus HS, Highland HM, Justice AE, Marouli E, Lindström J, Uusitupa M, Komulainen P, Lakka TA, Rauramaa R, Polasek O, Rudan I, Rolandsson O, Franks PW, Dedoussis G, Spector TD, Jousilahti P, Männistö S, Deary IJ, Starr JM, Langenberg C, Wareham NJ, Brown MJ, Dominiczak AF, Connell JM, Jukema JW, Sattar N, Ford I, Packard CJ, Esko T, Mägi R, Metspalu A, de Boer RA, van der Meer P, van der Harst P, Gambaro G, Ingelsson E, Lind L, de Bakker PI, Numans ME, Brandslund I, Christensen C, Petersen ER, Korpi-Hyövälti E, Oksa H, Chambers JC, Kooner JS, Blakemore AI, Franks S, Jarvelin MR, Husemoen LL, Linneberg A, Skaaby T, Thuesen B, Karpe F, Tuomilehto J, Doney AS, Morris AD, Palmer CN, Holmen OL, Hveem K, Willer CJ, Tuomi T, Groop L, Käräjämäki A, Palotie A, Ripatti S, Salomaa V, Alam DS, Majumder AA, Di Angelantonio E, Chowdhury R, McCarthy MI, Poulter N, Stanton AV, Sever P, Amouyel P, Arveiler D, Blankenberg S, Ferrières J, Kee F, Kuulasmaa K, Müller-Nurasyid M, Veronesi G, Virtamo J, Deloukas P, Elliott P, Zeggini E, Kathiresan S, Melander O, Kuusisto J, Laakso M, Padmanabhan S, Porteous DJ, Hayward C, Scotland G, Collins FS, Mohlke KL, Hansen T, Pedersen O, Boehnke M, Stringham HM, Frossard P, Newton-Cheh C, Tobin MD, Nordestgaard BG, Caulfield MJ, Mahajan A, Morris AP, Tomaszewski M, Samani NJ, Saleheen D, Asselbergs FW, Lindgren CM, Danesh J, Wain LV, Butterworth AS, Howson JM, Munroe PB. Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension. Nat Genet. 2016 Oct; 48(10):1151-61.View Related Profiles.

Liu, Chunyu
Lin, Honghuang
Ramachandran, Vasan

PMID: 27618447; PMCID: PMC5056636; DOI: 10.1038/ng.3654;

Ehret GB, Ferreira T, Chasman DI, Jackson AU, Schmidt EM, Johnson T, Thorleifsson G, Luan J, Donnelly LA, Kanoni S, Petersen AK, Pihur V, Strawbridge RJ, Shungin D, Hughes MF, Meirelles O, Kaakinen M, Bouatia-Naji N, Kristiansson K, Shah S, Kleber ME, Guo X, Lyytikäinen LP, Fava C, Eriksson N, Nolte IM, Magnusson PK, Salfati EL, Rallidis LS, Theusch E, Smith AJ, Folkersen L, Witkowska K, Pers TH, Joehanes R, Kim SK, Lataniotis L, Jansen R, Johnson AD, Warren H, Kim YJ, Zhao W, Wu Y, Tayo BO, Bochud M, Absher D, Adair LS, Amin N, Arking DE, Axelsson T, Baldassarre D, Balkau B, Bandinelli S, Barnes MR, Barroso I, Bevan S, Bis JC, Bjornsdottir G, Boehnke M, Boerwinkle E, Bonnycastle LL, Boomsma DI, Bornstein SR, Brown MJ, Burnier M, Cabrera CP, Chambers JC, Chang IS, Cheng CY, Chines PS, Chung RH, Collins FS, Connell JM, Döring A, Dallongeville J, Danesh J, de Faire U, Delgado G, Dominiczak AF, Doney AS, Drenos F, Edkins S, Eicher JD, Elosua R, Enroth S, Erdmann J, Eriksson P, Esko T, Evangelou E, Evans A, Fall T, Farrall M, Felix JF, Ferrières J, Ferrucci L, Fornage M, Forrester T, Franceschini N, Franco OH, Franco-Cereceda A, Fraser RM, Ganesh SK, Gao H, Gertow K, Gianfagna F, Gigante B, Giulianini F, Goel A, Goodall AH, Goodarzi MO, Gorski M, Gräßler J, Groves CJ, Gudnason V, Gyllensten U, Hallmans G, Hartikainen AL, Hassinen M, Havulinna AS, Hayward C, Hercberg S, Herzig KH, Hicks AA, Hingorani AD, Hirschhorn JN, Hofman A, Holmen J, Holmen OL, Hottenga JJ, Howard P, Hsiung CA, Hunt SC, Ikram MA, Illig T, Iribarren C, Jensen RA, Kähönen M, Kang HM, Kathiresan S, Keating BJ, Khaw KT, Kim YK, Kim E, Kivimaki M, Klopp N, Kolovou G, Komulainen P, Kooner JS, Kosova G, Krauss RM, Kuh D, Kutalik Z, Kuusisto J, Kvaløy K, Lakka TA, Lee NR, Lee IT, Lee WJ, Levy D, Li X, Liang KW, Lin H, Lin L, Lindström J, Lobbens S, Männistö S, Müller G, Müller-Nurasyid M, Mach F, Markus HS, Marouli E, McCarthy MI, McKenzie CA, Meneton P, Menni C, Metspalu A, Mijatovic V, Moilanen L, Montasser ME, Morris AD, Morrison AC, Mulas A, Nagaraja R, Narisu N, Nikus K, O'Donnell CJ, O'Reilly PF, Ong KK, Paccaud F, Palmer CD, Parsa A, Pedersen NL, Penninx BW, Perola M, Peters A, Poulter N, Pramstaller PP, Psaty BM, Quertermous T, Rao DC, Rasheed A, Rayner NW, Renström F, Rettig R, Rice KM, Roberts R, Rose LM, Rossouw J, Samani NJ, Sanna S, Saramies J, Schunkert H, Sebert S, Sheu WH, Shin YA, Sim X, Smit JH, Smith AV, Sosa MX, Spector TD, Stancáková A, Stanton AV, Stirrups KE, Stringham HM, Sundstrom J, Swift AJ, Syvänen AC, Tai ES, Tanaka T, Tarasov KV, Teumer A, Thorsteinsdottir U, Tobin MD, Tremoli E, Uitterlinden AG, Uusitupa M, Vaez A, Vaidya D, van Duijn CM, van Iperen EP, Vasan RS, Verwoert GC, Virtamo J, Vitart V, Voight BF, Vollenweider P, Wagner A, Wain LV, Wareham NJ, Watkins H, Weder AB, Westra HJ, Wilks R, Wilsgaard T, Wilson JF, Wong TY, Yang TP, Yao J, Yengo L, Zhang W, Zhao JH, Zhu X, Bovet P, Cooper RS, Mohlke KL, Saleheen D, Lee JY, Elliott P, Gierman HJ, Willer CJ, Franke L, Hovingh GK, Taylor KD, Dedoussis G, Sever P, Wong A, Lind L, Assimes TL, Njølstad I, Schwarz PE, Langenberg C, Snieder H, Caulfield MJ, Melander O, Laakso M, Saltevo J, Rauramaa R, Tuomilehto J, Ingelsson E, Lehtimäki T, Hveem K, Palmas W, März W, Kumari M, Salomaa V, Chen YD, Rotter JI, Froguel P, Jarvelin MR, Lakatta EG, Kuulasmaa K, Franks PW, Hamsten A, Wichmann HE, Palmer CN, Stefansson K, Ridker PM, Loos RJ, Chakravarti A, Deloukas P, Morris AP, Newton-Cheh C, Munroe PB. The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals. Nat Genet. 2016 Oct; 48(10):1171-84.View Related Profiles.

O'Donnell, Christopher
Lin, Honghuang
Ramachandran, Vasan

PMID: 27618452; PMCID: PMC5042863; DOI: 10.1038/ng.3667;

Liu C, Kraja AT, Smith JA, Brody JA, Franceschini N, Bis JC, Rice K, Morrison AC, Lu Y, Weiss S, Guo X, Palmas W, Martin LW, Chen YD, Surendran P, Drenos F, Cook JP, Auer PL, Chu AY, Giri A, Zhao W, Jakobsdottir J, Lin LA, Stafford JM, Amin N, Mei H, Yao J, Voorman A, Larson MG, Grove ML, Smith AV, Hwang SJ, Chen H, Huan T, Kosova G, Stitziel NO, Kathiresan S, Samani N, Schunkert H, Deloukas P, Li M, Fuchsberger C, Pattaro C, Gorski M, Kooperberg C, Papanicolaou GJ, Rossouw JE, Faul JD, Kardia SL, Bouchard C, Raffel LJ, Uitterlinden AG, Franco OH, Vasan RS, O'Donnell CJ, Taylor KD, Liu K, Bottinger EP, Gottesman O, Daw EW, Giulianini F, Ganesh S, Salfati E, Harris TB, Launer LJ, Dörr M, Felix SB, Rettig R, Völzke H, Kim E, Lee WJ, Lee IT, Sheu WH, Tsosie KS, Edwards DR, Liu Y, Correa A, Weir DR, Völker U, Ridker PM, Boerwinkle E, Gudnason V, Reiner AP, van Duijn CM, Borecki IB, Edwards TL, Chakravarti A, Rotter JI, Psaty BM, Loos RJ, Fornage M, Ehret GB, Newton-Cheh C, Levy D, Chasman DI. Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci. Nat Genet. 2016 Oct; 48(10):1162-70.View Related Profiles.

O'Donnell, Christopher
Liu, Chunyu
Larson, Martin
Hwang, Shih-Jen
Ramachandran, Vasan

PMID: 27618448; PMCID: PMC5320952; DOI: 10.1038/ng.3660;

Lorbeer R, Baumeister SE, Dörr M, Nauck M, Grotevendt A, Schlesinger S, Teumer A, Völzke H, Grabe HJ, Wallaschofski H, Vasan RS, Lieb W. Angiopoietin-2, its soluble receptor Tie-2, and metabolic syndrome components in a population-based sample. Obesity (Silver Spring). 2016 Oct; 24(10):2038-41. PMID: 27601273; DOI: 10.1002/oby.21632;

Meneton P, Lemogne C, Herquelot E, Bonenfant S, Larson MG, Vasan RS, Ménard J, Goldberg M, Zins M. A Global View of the Relationships between the Main Behavioural and Clinical Cardiovascular Risk Factors in the GAZEL Prospective Cohort. PLoS One. 2016; 11(9):e0162386.View Related Profiles.

Larson, Martin
Ramachandran, Vasan

PMID: 27598908; PMCID: PMC5012694; DOI: 10.1371/journal.pone.0162386;

Postmus I, Warren HR, Trompet S, Arsenault BJ, Avery CL, Bis JC, Chasman DI, de Keyser CE, Deshmukh HA, Evans DS, Feng Q, Li X, Smit RA, Smith AV, Sun F, Taylor KD, Arnold AM, Barnes MR, Barratt BJ, Betteridge J, Boekholdt SM, Boerwinkle E, Buckley BM, Chen YI, de Craen AJ, Cummings SR, Denny JC, Dubé MP, Durrington PN, Eiriksdottir G, Ford I, Guo X, Harris TB, Heckbert SR, Hofman A, Hovingh GK, Kastelein JJ, Launer LJ, Liu CT, Liu Y, Lumley T, McKeigue PM, Munroe PB, Neil A, Nickerson DA, Nyberg F, O'Brien E, O'Donnell CJ, Post W, Poulter N, Vasan RS, Rice K, Rich SS, Rivadeneira F, Sattar N, Sever P, Shaw-Hawkins S, Shields DC, Slagboom PE, Smith NL, Smith JD, Sotoodehnia N, Stanton A, Stott DJ, Stricker BH, Stürmer T, Uitterlinden AG, Wei WQ, Westendorp RG, Whitsel EA, Wiggins KL, Wilke RA, Ballantyne CM, Colhoun HM, Cupples LA, Franco OH, Gudnason V, Hitman G, Palmer CN, Psaty BM, Ridker PM, Stafford JM, Stein CM, Tardif JC, Caulfield MJ, Jukema JW, Rotter JI, Krauss RM. Meta-analysis of genome-wide association studies of HDL cholesterol response to statins. J Med Genet. 2016 Dec; 53(12):835-845.View Related Profiles.

Liu, Ching-Ti
O'Donnell, Christopher
Sun, Fangui
Cupples, L
Ramachandran, Vasan

PMID: 27587472; PMCID: PMC5309131; DOI: 10.1136/jmedgenet-2016-103966;

Shoamanesh A, Preis SR, Beiser AS, Kase CS, Wolf PA, Vasan RS, Benjamin EJ, Seshadri S, Romero JR. Circulating biomarkers and incident ischemic stroke in the Framingham Offspring Study. Neurology. 2016 Sep 20; 87(12):1206-11.View Related Profiles.

Beiser, Alexa
Shoamanesh, Ashkan
Kase, Carlos
Benjamin, Emelia
Romero, Jose
Wolf, Philip
Preis, Sarah
Seshadri, Sudha
Ramachandran, Vasan

PMID: 27558379; PMCID: PMC5035987; DOI: 10.1212/WNL.0000000000003115;

Ko D, Riles EM, Marcos EG, Magnani JW, Lubitz SA, Lin H, Long MT, Schnabel RB, McManus DD, Ellinor PT, Ramachandran VS, Wang TJ, Gerszten RE, Benjamin EJ, Yin X, Rienstra M. Metabolomic Profiling in Relation to New-Onset Atrial Fibrillation (from the Framingham Heart Study). Am J Cardiol. 2016 Nov 15; 118(10):1493-1496.View Related Profiles.

Ko, Darae
Benjamin, Emelia
Lin, Honghuang
Long, Michelle
Ramachandran, Vasan

PMID: 27666170; PMCID: PMC5097881; DOI: 10.1016/j.amjcard.2016.08.010;

Pase MP, Beiser A, Himali JJ, Tsao C, Satizabal CL, Vasan RS, Seshadri S, Mitchell GF. Aortic Stiffness and the Risk of Incident Mild Cognitive Impairment and Dementia. Stroke. 2016 Sep; 47(9):2256-61.View Related Profiles.

Beiser, Alexa
Satizabal, Claudia
Himali, Jayandra
Seshadri, Sudha
Ramachandran, Vasan

PMID: 27491735; PMCID: PMC4995162; DOI: 10.1161/STROKEAHA.116.013508;

Mitchell GF, Hwang SJ, Larson MG, Hamburg NM, Benjamin EJ, Vasan RS, Levy D, Vita JA. Transfer function-derived central pressure and cardiovascular disease events: the Framingham Heart Study. J Hypertens. 2016 Aug; 34(8):1528-34.View Related Profiles.

Levy, Daniel
Benjamin, Emelia
Larson, Martin
Hamburg, Naomi
Hwang, Shih-Jen
Ramachandran, Vasan

PMID: 27219486; PMCID: PMC6206853; DOI: 10.1097/HJH.0000000000000968;

Dhingra R, Vasan RS. Biomarkers in cardiovascular disease: Statistical assessment and section on key novel heart failure biomarkers. Trends Cardiovasc Med. 2017 Feb; 27(2):123-133. PMID: 27576060; PMCID: PMC5253084; DOI: 10.1016/j.tcm.2016.07.005;

Ngo D, Sinha S, Shen D, Kuhn EW, Keyes MJ, Shi X, Benson MD, O'Sullivan JF, Keshishian H, Farrell LA, Fifer MA, Vasan RS, Sabatine MS, Larson MG, Carr SA, Wang TJ, Gerszten RE. Aptamer-Based Proteomic Profiling Reveals Novel Candidate Biomarkers and Pathways in Cardiovascular Disease. Circulation. 2016 Jul 26; 134(4):270-85.View Related Profiles.

Larson, Martin
Ramachandran, Vasan

PMID: 27444932; PMCID: PMC4963294; DOI: 10.1161/CIRCULATIONAHA.116.021803;

Rhee EP, Yang Q, Yu B, Liu X, Cheng S, Deik A, Pierce KA, Bullock K, Ho JE, Levy D, Florez JC, Kathiresan S, Larson MG, Vasan RS, Clish CB, Wang TJ, Boerwinkle E, O'Donnell CJ, Gerszten RE. An exome array study of the plasma metabolome. Nat Commun. 2016 07 25; 7:12360.View Related Profiles.

O'Donnell, Christopher
Larson, Martin
Yang, Qiong
Ramachandran, Vasan

PMID: 27453504; PMCID: PMC4962516; DOI: 10.1038/ncomms12360;

Shaikh AY, Wang N, Yin X, Larson MG, Vasan RS, Hamburg NM, Magnani JW, Ellinor PT, Lubitz SA, Mitchell GF, Benjamin EJ, McManus DD. Relations of Arterial Stiffness and Brachial Flow-Mediated Dilation With New-Onset Atrial Fibrillation: The Framingham Heart Study. Hypertension. 2016 Sep; 68(3):590-6.View Related Profiles.

Benjamin, Emelia
Larson, Martin
Hamburg, Naomi
Ramachandran, Vasan

PMID: 27456517; DOI: 10.1161/HYPERTENSIONAHA.116.07650;

Andersson C, Quiroz R, Enserro D, Larson MG, Hamburg NM, Vita JA, Levy D, Benjamin EJ, Mitchell GF, Vasan RS. Association of Parental Hypertension With Arterial Stiffness in Nonhypertensive Offspring: The Framingham Heart Study. Hypertension. 2016 Sep; 68(3):584-9.View Related Profiles.

Levy, Daniel
Benjamin, Emelia
Larson, Martin
Hamburg, Naomi
Ramachandran, Vasan

PMID: 27456526; PMCID: PMC5002314; DOI: 10.1161/HYPERTENSIONAHA.116.07426;

Puurunen MK, Enserro D, Xanthakis V, Larson MG, Benjamin EJ, Tofler GH, Wollert KC, O'Donnell CJ, Vasan RS. Biomarkers for the prediction of venous thromboembolism in the community. Thromb Res. 2016 Sep; 145:34-9.View Related Profiles.

O'Donnell, Christopher
Benjamin, Emelia
Larson, Martin
Xanthakis, Vanessa
Ramachandran, Vasan

PMID: 27447083; DOI: 10.1016/j.thromres.2016.07.006;

Rahman F, Yin X, Larson MG, Ellinor PT, Lubitz SA, Vasan RS, McManus DD, Magnani JW, Benjamin EJ. Trajectories of Risk Factors and Risk of New-Onset Atrial Fibrillation in the Framingham Heart Study. Hypertension. 2016 Sep; 68(3):597-605.View Related Profiles.

Benjamin, Emelia
Larson, Martin
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PMID: 27512109; PMCID: PMC4982514; DOI: 10.1161/HYPERTENSIONAHA.116.07683;

Haring R, Enserro D, Xanthakis V, Mitchell GF, Benjamin EJ, Hamburg NM, Sullivan L, Nauck M, Wallaschofski H, Vasan RS. Plasma Fibroblast Growth Factor 23: Clinical Correlates and Association With Cardiovascular Disease and Mortality in the Framingham Heart Study. J Am Heart Assoc. 2016 Jul 06; 5(7).View Related Profiles.

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PMID: 27385427; PMCID: PMC5015386; DOI: 10.1161/JAHA.116.003486;

Xanthakis V, Enserro DM, Larson MG, Wollert KC, Januzzi JL, Levy D, Aragam J, Benjamin EJ, Cheng S, Wang TJ, Mitchell GF, Vasan RS. Prevalence, Neurohormonal Correlates, and Prognosis of Heart Failure Stages in the Community. JACC Heart Fail. 2016 Oct; 4(10):808-815.View Related Profiles.

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PMID: 27395350; DOI: 10.1016/j.jchf.2016.05.001;

Kaess BM, Preis SR, Beiser A, Sawyer DB, Chen TC, Seshadri S, Vasan RS. Circulating vascular endothelial growth factor and the risk of cardiovascular events. Heart. 2016 Dec 01; 102(23):1898-1901.View Related Profiles.

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PMID: 27354275; DOI: 10.1136/heartjnl-2015-309155;

MacRae CA, Vasan RS. The Future of Genetics and Genomics: Closing the Phenotype Gap in Precision Medicine. Circulation. 2016 Jun 21; 133(25):2634-9. PMID: 27324359; PMCID: PMC6188655; DOI: 10.1161/CIRCULATIONAHA.116.022547;

Teumer A, Qi Q, Nethander M, Aschard H, Bandinelli S, Beekman M, Berndt SI, Bidlingmaier M, Broer L, Cappola A, Ceda GP, Chanock S, Chen MH, Chen TC, Chen YD, Chung J, Del Greco Miglianico F, Eriksson J, Ferrucci L, Friedrich N, Gnewuch C, Goodarzi MO, Grarup N, Guo T, Hammer E, Hayes RB, Hicks AA, Hofman A, Houwing-Duistermaat JJ, Hu F, Hunter DJ, Husemoen LL, Isaacs A, Jacobs KB, Janssen JA, Jansson JO, Jehmlich N, Johnson S, Juul A, Karlsson M, Kilpelainen TO, Kovacs P, Kraft P, Li C, Linneberg A, Liu Y, Loos RJ, Lorentzon M, Lu Y, Maggio M, Magi R, Meigs J, Mellström D, Nauck M, Newman AB, Pollak MN, Pramstaller PP, Prokopenko I, Psaty BM, Reincke M, Rimm EB, Rotter JI, Saint Pierre A, Schurmann C, Seshadri S, Sjögren K, Slagboom PE, Strickler HD, Stumvoll M, Suh Y, Sun Q, Zhang C, Svensson J, Tanaka T, Tare A, Tönjes A, Uh HW, van Duijn CM, van Heemst D, Vandenput L, Vasan RS, Völker U, Willems SM, Ohlsson C, Wallaschofski H, Kaplan RC. Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits. Aging Cell. 2016 Oct; 15(5):811-24.View Related Profiles.

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PMID: 27329260; PMCID: PMC5013013; DOI: 10.1111/acel.12490;

Vasan RS, Benjamin EJ. The Future of Cardiovascular Epidemiology. Circulation. 2016 Jun 21; 133(25):2626-33.View Related Profiles.

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PMID: 27324358; PMCID: PMC4974092; DOI: 10.1161/CIRCULATIONAHA.116.023528;

Januzzi JL, Lyass A, Liu Y, Gaggin H, Trebnick A, Maisel AS, D'Agostino RB, Wang TJ, Massaro J, Vasan RS. Circulating Proneurotensin Concentrations and Cardiovascular Disease Events in the Community: The Framingham Heart Study. Arterioscler Thromb Vasc Biol. 2016 Aug; 36(8):1692-7.View Related Profiles.

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PMID: 27312221; PMCID: PMC4965295; DOI: 10.1161/ATVBAHA.116.307847;

Waikar SS, Sabbisetti V, Ärnlöv J, Carlsson AC, Coresh J, Feldman HI, Foster MC, Fufaa GD, Helmersson-Karlqvist J, Hsu CY, Kimmel PL, Larsson A, Liu Y, Lind L, Liu KD, Mifflin TE, Nelson RG, Risérus U, Vasan RS, Xie D, Zhang X, Bonventre JV. Relationship of proximal tubular injury to chronic kidney disease as assessed by urinary kidney injury molecule-1 in five cohort studies. Nephrol Dial Transplant. 2016 Sep; 31(9):1460-70.View Related Profiles.

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PMID: 27270293; PMCID: PMC5009290; DOI: 10.1093/ndt/gfw203;

Santhanakrishnan R, Wang N, Larson MG, Magnani JW, McManus DD, Lubitz SA, Ellinor PT, Cheng S, Vasan RS, Lee DS, Wang TJ, Levy D, Benjamin EJ, Ho JE. Response to Letter Regarding Article, "Atrial Fibrillation Begets Heart Failure and Vice Versa: Temporal Associations and Differences in Preserved Versus Reduced Ejection Fraction". Circulation. 2016 Jun 7; 133(23):e692-3.View Related Profiles.

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PMID: 27267541; PMCID: PMC4902166; DOI: 10.1161/CIRCULATIONAHA.116.022835;

Tsao CW, Lyass A, Larson MG, Cheng S, Lam CS, Aragam JR, Benjamin EJ, Vasan RS. Prognosis of Adults With Borderline Left Ventricular Ejection Fraction. JACC Heart Fail. 2016 Jun; 4(6):502-10.View Related Profiles.

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PMID: 27256754; PMCID: PMC4932891; DOI: 10.1016/j.jchf.2016.03.003;

Ho JE, Enserro D, Brouwers FP, Kizer JR, Shah SJ, Psaty BM, Bartz TM, Santhanakrishnan R, Lee DS, Chan C, Liu K, Blaha MJ, Hillege HL, van der Harst P, van Gilst WH, Kop WJ, Gansevoort RT, Vasan RS, Gardin JM, Levy D, Gottdiener JS, de Boer RA, Larson MG. Predicting Heart Failure With Preserved and Reduced Ejection Fraction: The International Collaboration on Heart Failure Subtypes. Circ Heart Fail. 2016 Jun; 9(6).View Related Profiles.

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PMID: 27266854; PMCID: PMC4902276; DOI: 10.1161/CIRCHEARTFAILURE.115.003116;

Spartano NL, Lyass A, Larson MG, Lewis GD, Vasan RS. Submaximal Exercise Systolic Blood Pressure and Heart Rate at 20 Years of Follow-up: Correlates in the Framingham Heart Study. J Am Heart Assoc. 2016 May 27; 5(6).View Related Profiles.

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PMID: 27233297; PMCID: PMC4937245; DOI: 10.1161/JAHA.115.002821;

Smith JG, Felix JF, Morrison AC, Kalogeropoulos A, Trompet S, Wilk JB, Gidlöf O, Wang X, Morley M, Mendelson M, Joehanes R, Ligthart S, Shan X, Bis JC, Wang YA, Sjögren M, Ngwa J, Brandimarto J, Stott DJ, Aguilar D, Rice KM, Sesso HD, Demissie S, Buckley BM, Taylor KD, Ford I, Yao C, Liu C, Sotoodehnia N, van der Harst P, Stricker BH, Kritchevsky SB, Liu Y, Gaziano JM, Hofman A, Moravec CS, Uitterlinden AG, Kellis M, van Meurs JB, Margulies KB, Dehghan A, Levy D, Olde B, Psaty BM, Cupples LA, Jukema JW, Djousse L, Franco OH, Boerwinkle E, Boyer LA, Newton-Cheh C, Butler J, Vasan RS, Cappola TP, Smith NL. Discovery of Genetic Variation on Chromosome 5q22 Associated with Mortality in Heart Failure. PLoS Genet. 2016 May; 12(5):e1006034.View Related Profiles.

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PMID: 27149122; PMCID: PMC4858216; DOI: 10.1371/journal.pgen.1006034;

Lee JJ, Britton KA, Pedley A, Massaro JM, Speliotes EK, Murabito JM, Hoffmann U, Ingram C, Keaney JF, Vasan RS, Fox CS. Adipose Tissue Depots and Their Cross-Sectional Associations With Circulating Biomarkers of Metabolic Regulation. J Am Heart Assoc. 2016 May 04; 5(5).View Related Profiles.

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PMID: 27146446; PMCID: PMC4889173; DOI: 10.1161/JAHA.115.002936;

Nayor M, Vasan RS. Recent Update to the US Cholesterol Treatment Guidelines: A Comparison With International Guidelines. Circulation. 2016 May 03; 133(18):1795-806.View Related Profiles.

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PMID: 27143546; PMCID: PMC4857879; DOI: 10.1161/CIRCULATIONAHA.116.021407;

Kim EJ, Yin X, Fontes JD, Magnani JW, Lubitz SA, McManus DD, Seshadri S, Vasan RS, Ellinor PT, Larson MG, Benjamin EJ, Rienstra M. Atrial fibrillation without comorbidities: Prevalence, incidence and prognosis (from the Framingham Heart Study). Am Heart J. 2016 Jul; 177:138-44.View Related Profiles.

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PMID: 27297859; PMCID: PMC4908973; DOI: 10.1016/j.ahj.2016.03.023;

Li W, Wilker EH, Dorans KS, Rice MB, Schwartz J, Coull BA, Koutrakis P, Gold DR, Keaney JF, Lin H, Vasan RS, Benjamin EJ, Mittleman MA. Short-Term Exposure to Air Pollution and Biomarkers of Oxidative Stress: The Framingham Heart Study. J Am Heart Assoc. 2016 Apr 28; 5(5).View Related Profiles.

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PMID: 27126478; PMCID: PMC4889166; DOI: 10.1161/JAHA.115.002742;

Niiranen TJ, Vasan RS. Epidemiology of cardiovascular disease: recent novel outlooks on risk factors and clinical approaches. Expert Rev Cardiovasc Ther. 2016 Jul; 14(7):855-69. PMID: 27057779; PMCID: PMC4961207; DOI: 10.1080/14779072.2016.1176528;

Pase MP, Beiser A, Enserro D, Xanthakis V, Aparicio H, Satizabal CL, Himali JJ, Kase CS, Vasan RS, DeCarli C, Seshadri S. Association of Ideal Cardiovascular Health With Vascular Brain Injury and Incident Dementia. Stroke. 2016 May; 47(5):1201-6.View Related Profiles.

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PMID: 27073239; PMCID: PMC5006676; DOI: 10.1161/STROKEAHA.115.012608;

Fox ER, Samdarshi TE, Musani SK, Pencina MJ, Sung JH, Bertoni AG, Xanthakis V, Balfour PC, Shreenivas SS, Covington C, Liebson PR, Sarpong DF, Butler KR, Mosley TH, Rosamond WD, Folsom AR, Herrington DM, Vasan RS, Taylor HA. Development and Validation of Risk Prediction Models for Cardiovascular Events in Black Adults: The Jackson Heart Study Cohort. JAMA Cardiol. 2016 04 01; 1(1):15-25.View Related Profiles.

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PMID: 27437649; PMCID: PMC5115626; DOI: 10.1001/jamacardio.2015.0300;

Santhanakrishnan R, Wang N, Larson MG, Magnani JM, Vasan RS, Wang TJ, Yap J, Feng L, Yap KB, Ong HY, Ng TP, Richards AM, Lam CS, Ho JE. Racial Differences in Electrocardiographic Characteristics and Prognostic Significance in Whites Versus Asians. J Am Heart Assoc. 2016 Mar 25; 5(3):e002956.View Related Profiles.

Larson, Martin
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PMID: 27016575; PMCID: PMC4943269; DOI: 10.1161/JAHA.115.002956;

Kaess BM, Rong J, Larson MG, Hamburg NM, Vita JA, Cheng S, Aragam J, Levy D, Benjamin EJ, Vasan RS, Mitchell GF. Relations of Central Hemodynamics and Aortic Stiffness with Left Ventricular Structure and Function: The Framingham Heart Study. J Am Heart Assoc. 2016 Mar 25; 5(3):e002693.View Related Profiles.

Kaess, Bernhard
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PMID: 27016574; PMCID: PMC4943246; DOI: 10.1161/JAHA.115.002693;

Delling FN, Rong J, Larson MG, Lehman B, Fuller D, Osypiuk E, Stantchev P, Hackman B, Manning WJ, Benjamin EJ, Levine RA, Vasan RS. Evolution of Mitral Valve Prolapse: Insights From the Framingham Heart Study. Circulation. 2016 Apr 26; 133(17):1688-95.View Related Profiles.

Benjamin, Emelia
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PMID: 27006478; PMCID: PMC4856536; DOI: 10.1161/CIRCULATIONAHA.115.020621;

Romero JR, Preis SR, Beiser A, DeCarli C, D'Agostino RB, Wolf PA, Vasan RS, Polak JF, Seshadri S. Carotid Atherosclerosis and Cerebral Microbleeds: The Framingham Heart Study. J Am Heart Assoc. 2016 Mar 18; 5(3):e002377.View Related Profiles.

Beiser, Alexa
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PMID: 26994127; PMCID: PMC4943235; DOI: 10.1161/JAHA.115.002377;

Schnabel RB, Maas R, Wang N, Yin X, Larson MG, Levy D, Ellinor PT, Lubitz SA, McManus DD, Magnani JW, Atzler D, Böger RH, Schwedhelm E, Vasan RS, Benjamin EJ. Asymmetric dimethylarginine, related arginine derivatives, and incident atrial fibrillation. Am Heart J. 2016 Jun; 176:100-6.View Related Profiles.

Benjamin, Emelia
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PMID: 27264226; PMCID: PMC4899814; DOI: 10.1016/j.ahj.2016.03.007;

Maillard P, Mitchell GF, Himali JJ, Beiser A, Tsao CW, Pase MP, Satizabal CL, Vasan RS, Seshadri S, DeCarli C. Effects of Arterial Stiffness on Brain Integrity in Young Adults From the Framingham Heart Study. Stroke. 2016 Apr; 47(4):1030-6.View Related Profiles.

Beiser, Alexa
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PMID: 26965846; PMCID: PMC4811686; DOI: 10.1161/STROKEAHA.116.012949;

Dehghan A, Bis JC, White CC, Smith AV, Morrison AC, Cupples LA, Trompet S, Chasman DI, Lumley T, Völker U, Buckley BM, Ding J, Jensen MK, Folsom AR, Kritchevsky SB, Girman CJ, Ford I, Dörr M, Salomaa V, Uitterlinden AG, Eiriksdottir G, Vasan RS, Franceschini N, Carty CL, Virtamo J, Demissie S, Amouyel P, Arveiler D, Heckbert SR, Ferrières J, Ducimetière P, Smith NL, Wang YA, Siscovick DS, Rice KM, Wiklund PG, Taylor KD, Evans A, Kee F, Rotter JI, Karvanen J, Kuulasmaa K, Heiss G, Kraft P, Launer LJ, Hofman A, Markus MR, Rose LM, Silander K, Wagner P, Benjamin EJ, Lohman K, Stott DJ, Rivadeneira F, Harris TB, Levy D, Liu Y, Rimm EB, Jukema JW, Völzke H, Ridker PM, Blankenberg S, Franco OH, Gudnason V, Psaty BM, Boerwinkle E, O'Donnell CJ. Genome-Wide Association Study for Incident Myocardial Infarction and Coronary Heart Disease in Prospective Cohort Studies: The CHARGE Consortium. PLoS One. 2016; 11(3):e0144997.View Related Profiles.

O'Donnell, Christopher
Benjamin, Emelia
Cupples, L
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PMID: 26950853; PMCID: PMC4780701; DOI: 10.1371/journal.pone.0144997;

Foster MC, Coresh J, Hsu CY, Xie D, Levey AS, Nelson RG, Eckfeldt JH, Vasan RS, Kimmel PL, Schelling J, Simonson M, Sondheimer JH, Anderson AH, Akkina S, Feldman HI, Kusek JW, Ojo AO, Inker LA. Serum ß-Trace Protein and ß2-Microglobulin as Predictors of ESRD, Mortality, and Cardiovascular Disease in Adults With CKD in the Chronic Renal Insufficiency Cohort (CRIC) Study. Am J Kidney Dis. 2016 Jul; 68(1):68-76. PMID: 26948990; PMCID: PMC4921300; DOI: 10.1053/j.ajkd.2016.01.015;

Travison TG, O'Donnell CJ, Bhasin S, Massaro JM, Hoffmann U, Vasan RS, D'Agostino RB, Basaria S. Circulating Sex Steroids and Vascular Calcification in Community-Dwelling Men: The Framingham Heart Study. J Clin Endocrinol Metab. 2016 May; 101(5):2160-7.View Related Profiles.

O'Donnell, Christopher
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PMID: 26930184; PMCID: PMC4870846; DOI: 10.1210/jc.2015-4299;

Ljungman PL, Wilker EH, Rice MB, Austin E, Schwartz J, Gold DR, Koutrakis P, Benjamin EJ, Vita JA, Mitchell GF, Vasan RS, Hamburg NM, Mittleman MA. The Impact of Multipollutant Clusters on the Association Between Fine Particulate Air Pollution and Microvascular Function. Epidemiology. 2016 Mar; 27(2):194-201.View Related Profiles.

Benjamin, Emelia
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PMID: 26562062; PMCID: PMC5257194; DOI: 10.1097/EDE.0000000000000415;

Lee JJ, Pedley A, Hoffmann U, Massaro JM, Keaney JF, Vasan RS, Fox CS. Cross-Sectional Associations of Computed Tomography (CT)-Derived Adipose Tissue Density and Adipokines: The Framingham Heart Study. J Am Heart Assoc. 2016 Feb 29; 5(3):e002545.View Related Profiles.

Massaro, Joseph
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PMID: 26927600; PMCID: PMC4943240; DOI: 10.1161/JAHA.115.002545;

Choi SH, Ruggiero D, Sorice R, Song C, Nutile T, Vernon Smith A, Concas MP, Traglia M, Barbieri C, Ndiaye NC, Stathopoulou MG, Lagou V, Maestrale GB, Sala C, Debette S, Kovacs P, Lind L, Lamont J, Fitzgerald P, Tönjes A, Gudnason V, Toniolo D, Pirastu M, Bellenguez C, Vasan RS, Ingelsson E, Leutenegger AL, Johnson AD, DeStefano AL, Visvikis-Siest S, Seshadri S, Ciullo M. Six Novel Loci Associated with Circulating VEGF Levels Identified by a Meta-analysis of Genome-Wide Association Studies. PLoS Genet. 2016 Feb; 12(2):e1005874.View Related Profiles.

DeStefano, Anita
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PMID: 26910538; PMCID: PMC4766012; DOI: 10.1371/journal.pgen.1005874;

Andersson C, Enserro D, Sullivan L, Wang TJ, Januzzi JL, Benjamin EJ, Vita JA, Hamburg NM, Larson MG, Mitchell GF, Vasan RS. Relations of circulating GDF-15, soluble ST2, and troponin-I concentrations with vascular function in the community: The Framingham Heart Study. Atherosclerosis. 2016 May; 248:245-51.View Related Profiles.

Benjamin, Emelia
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PMID: 26972631; PMCID: PMC5018232; DOI: 10.1016/j.atherosclerosis.2016.02.013;

Abulaban KM, Song H, Zhang X, Kimmel PL, Kusek JW, Nelson RG, Feldman HI, Vasan RS, Ying J, Mauer M, Nelsestuen GL, Bennett M, Brunner HI, Rovin BH. Predicting decline of kidney function in lupus nephritis using urine biomarkers. Lupus. 2016 Aug; 25(9):1012-8. PMID: 26873651; PMCID: PMC4945408; DOI: 10.1177/0961203316631629;

Ho JE, Larson MG, Ghorbani A, Cheng S, Chen MH, Keyes M, Rhee EP, Clish CB, Vasan RS, Gerszten RE, Wang TJ. Metabolomic Profiles of Body Mass Index in the Framingham Heart Study Reveal Distinct Cardiometabolic Phenotypes. PLoS One. 2016; 11(2):e0148361.View Related Profiles.

Larson, Martin
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PMID: 26863521; PMCID: PMC4749349; DOI: 10.1371/journal.pone.0148361;

Willems SM, Cornes BK, Brody JA, Morrison AC, Lipovich L, Dauriz M, Chen Y, Liu CT, Rybin DV, Gibbs RA, Muzny D, Pankow JS, Psaty BM, Boerwinkle E, Rotter JI, Siscovick DS, Vasan RS, Kaplan RC, Isaacs A, Dupuis J, van Duijn CM, Meigs JB. Association of the IGF1 gene with fasting insulin levels. Eur J Hum Genet. 2016 Aug; 24(9):1337-43.View Related Profiles.

Liu, Ching-Ti
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PMID: 26860063; PMCID: PMC4989214; DOI: 10.1038/ejhg.2016.4;

Spartano NL, Himali JJ, Beiser AS, Lewis GD, DeCarli C, Vasan RS, Seshadri S. Midlife exercise blood pressure, heart rate, and fitness relate to brain volume 2 decades later. Neurology. 2016 Apr 5; 86(14):1313-9.View Related Profiles.

Beiser, Alexa
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PMID: 26865519; PMCID: PMC4826343; DOI: 10.1212/WNL.0000000000002415;

Tofler GH, Massaro J, O'Donnell CJ, Wilson PW, Vasan RS, Sutherland PA, Meigs JB, Levy D, D'Agostino RB. Plasminogen activator inhibitor and the risk of cardiovascular disease: The Framingham Heart Study. Thromb Res. 2016 Apr; 140:30-5.View Related Profiles.

O'Donnell, Christopher
Massaro, Joseph
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PMID: 26896607; PMCID: PMC5722217; DOI: 10.1016/j.thromres.2016.02.002;

Pattaro C, Teumer A, Gorski M, Chu AY, Li M, Mijatovic V, Garnaas M, Tin A, Sorice R, Li Y, Taliun D, Olden M, Foster M, Yang Q, Chen MH, Pers TH, Johnson AD, Ko YA, Fuchsberger C, Tayo B, Nalls M, Feitosa MF, Isaacs A, Dehghan A, d'Adamo P, Adeyemo A, Dieffenbach AK, Zonderman AB, Nolte IM, van der Most PJ, Wright AF, Shuldiner AR, Morrison AC, Hofman A, Smith AV, Dreisbach AW, Franke A, Uitterlinden AG, Metspalu A, Tonjes A, Lupo A, Robino A, Johansson Å, Demirkan A, Kollerits B, Freedman BI, Ponte B, Oostra BA, Paulweber B, Krämer BK, Mitchell BD, Buckley BM, Peralta CA, Hayward C, Helmer C, Rotimi CN, Shaffer CM, Müller C, Sala C, van Duijn CM, Saint-Pierre A, Ackermann D, Shriner D, Ruggiero D, Toniolo D, Lu Y, Cusi D, Czamara D, Ellinghaus D, Siscovick DS, Ruderfer D, Gieger C, Grallert H, Rochtchina E, Atkinson EJ, Holliday EG, Boerwinkle E, Salvi E, Bottinger EP, Murgia F, Rivadeneira F, Ernst F, Kronenberg F, Hu FB, Navis GJ, Curhan GC, Ehret GB, Homuth G, Coassin S, Thun GA, Pistis G, Gambaro G, Malerba G, Montgomery GW, Eiriksdottir G, Jacobs G, Li G, Wichmann HE, Campbell H, Schmidt H, Wallaschofski H, Völzke H, Brenner H, Kroemer HK, Kramer H, Lin H, Leach IM, Ford I, Guessous I, Rudan I, Prokopenko I, Borecki I, Heid IM, Kolcic I, Persico I, Jukema JW, Wilson JF, Felix JF, Divers J, Lambert JC, Stafford JM, Gaspoz JM, Smith JA, Faul JD, Wang JJ, Ding J, Hirschhorn JN, Attia J, Whitfield JB, Chalmers J, Viikari J, Coresh J, Denny JC, Karjalainen J, Fernandes JK, Endlich K, Butterbach K, Keene KL, Lohman K, Portas L, Launer LJ, Lyytikäinen LP, Yengo L, Franke L, Ferrucci L, Rose LM, Kedenko L, Rao M, Struchalin M, Kleber ME, Cavalieri M, Haun M, Cornelis MC, Ciullo M, Pirastu M, de Andrade M, McEvoy MA, Woodward M, Adam M, Cocca M, Nauck M, Imboden M, Waldenberger M, Pruijm M, Metzger M, Stumvoll M, Evans MK, Sale MM, Kähönen M, Boban M, Bochud M, Rheinberger M, Verweij N, Bouatia-Naji N, Martin NG, Hastie N, Probst-Hensch N, Soranzo N, Devuyst O, Raitakari O, Gottesman O, Franco OH, Polasek O, Gasparini P, Munroe PB, Ridker PM, Mitchell P, Muntner P, Meisinger C, Smit JH, Kovacs P, Wild PS, Froguel P, Rettig R, Mägi R, Biffar R, Schmidt R, Middelberg RP, Carroll RJ, Penninx BW, Scott RJ, Katz R, Sedaghat S, Wild SH, Kardia SL, Ulivi S, Hwang SJ, Enroth S, Kloiber S, Trompet S, Stengel B, Hancock SJ, Turner ST, Rosas SE, Stracke S, Harris TB, Zeller T, Zemunik T, Lehtimäki T, Illig T, Aspelund T, Nikopensius T, Esko T, Tanaka T, Gyllensten U, Völker U, Emilsson V, Vitart V, Aalto V, Gudnason V, Chouraki V, Chen WM, Igl W, März W, Koenig W, Lieb W, Loos RJ, Liu Y, Snieder H, Pramstaller PP, Parsa A, O'Connell JR, Susztak K, Hamet P, Tremblay J, de Boer IH, Böger CA, Goessling W, Chasman DI, Köttgen A, Kao WH, Fox CS. Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function. Nat Commun. 2016; 7:10023.View Related Profiles.

Lin, Honghuang
Cupples, L
Yang, Qiong
Seshadri, Sudha
Ramachandran, Vasan

PMID: 26831199; PMCID: PMC4735748; DOI: 10.1038/ncomms10023;

Tsao CW, Himali JJ, Beiser AS, Larson MG, DeCarli C, Vasan RS, Mitchell GF, Seshadri S. Association of arterial stiffness with progression of subclinical brain and cognitive disease. Neurology. 2016 Feb 16; 86(7):619-26.View Related Profiles.

Beiser, Alexa
Himali, Jayandra
Larson, Martin
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PMID: 26791155; PMCID: PMC4762417; DOI: 10.1212/WNL.0000000000002368;

Pase MP, Himali JJ, Mitchell GF, Beiser A, Maillard P, Tsao C, Larson MG, DeCarli C, Vasan RS, Seshadri S. Association of Aortic Stiffness With Cognition and Brain Aging in Young and Middle-Aged Adults: The Framingham Third Generation Cohort Study. Hypertension. 2016 Mar; 67(3):513-9.View Related Profiles.

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Himali, Jayandra
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PMID: 26754644; PMCID: PMC4752398; DOI: 10.1161/HYPERTENSIONAHA.115.06610;

Santhanakrishnan R, Wang N, Larson MG, Magnani JW, McManus DD, Lubitz SA, Ellinor PT, Cheng S, Vasan RS, Lee DS, Wang TJ, Levy D, Benjamin EJ, Ho JE. Atrial Fibrillation Begets Heart Failure and Vice Versa: Temporal Associations and Differences in Preserved Versus Reduced Ejection Fraction. Circulation. 2016 Feb 2; 133(5):484-92.View Related Profiles.

Levy, Daniel
Benjamin, Emelia
Magnani, Jared
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Ramachandran, Vasan

PMID: 26746177; PMCID: PMC4738087; DOI: 10.1161/CIRCULATIONAHA.115.018614;

Karakis I, Pase MP, Beiser A, Booth SL, Jacques PF, Rogers G, DeCarli C, Vasan RS, Wang TJ, Himali JJ, Annweiler C, Seshadri S. Association of Serum Vitamin D with the Risk of Incident Dementia and Subclinical Indices of Brain Aging: The Framingham Heart Study. J Alzheimers Dis. 2016; 51(2):451-61.View Related Profiles.

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Himali, Jayandra
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PMID: 26890771; PMCID: PMC4911705; DOI: 10.3233/JAD-150991;

Nayor M, Wang N, Larson MG, Vasan RS, Levy D, Ho JE. Circulating Galectin-3 Is Associated With Cardiometabolic Disease in the Community. J Am Heart Assoc. 2015 Dec 31; 5(1).View Related Profiles.

Larson, Martin
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PMID: 26722123; PMCID: PMC4859357; DOI: 10.1161/JAHA.115.002347;

Nayor M, Enserro DM, Vasan RS, Xanthakis V. Cardiovascular Health Status and Incidence of Heart Failure in the Framingham Offspring Study. Circ Heart Fail. 2016 Jan; 9(1):e002416.View Related Profiles.

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PMID: 26699391; PMCID: PMC4692176; DOI: 10.1161/CIRCHEARTFAILURE.115.002416;

Nayor M, Enserro DM, Beiser AS, Cheng S, DeCarli C, Vasan RS, Seshadri S. Association of Exhaled Carbon Monoxide With Stroke Incidence and Subclinical Vascular Brain Injury: Framingham Heart Study. Stroke. 2016 Feb; 47(2):383-9.View Related Profiles.

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PMID: 26696648; PMCID: PMC4729607; DOI: 10.1161/STROKEAHA.115.010405;

Tsao CW, Vasan RS. Cohort Profile: The Framingham Heart Study (FHS): overview of milestones in cardiovascular epidemiology. Int J Epidemiol. 2015 Dec; 44(6):1800-13. PMID: 26705418; PMCID: PMC5156338; DOI: 10.1093/ije/dyv337;

Tsao CW, Vasan RS. The Framingham Heart Study: past, present and future. Int J Epidemiol. 2015 Dec; 44(6):1763-6. PMID: 26705413; DOI: 10.1093/ije/dyv336;

Zachariah JP, Hwang S, Hamburg NM, Benjamin EJ, Larson MG, Levy D, Vita JA, Sullivan LM, Mitchell GF, Vasan RS. Circulating Adipokines and Vascular Function: Cross-Sectional Associations in a Community-Based Cohort. Hypertension. 2016 Feb; 67(2):294-300.View Related Profiles.

Levy, Daniel
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PMID: 26628673; PMCID: PMC4845672; DOI: 10.1161/HYPERTENSIONAHA.115.05949;

Chami HA, Vasan RS, Larson MG, Benjamin EJ, Mitchell GF, Gottlieb DJ. The association between sleep-disordered breathing and aortic stiffness in a community cohort. Sleep Med. 2016 Mar; 19:69-74.View Related Profiles.

Benjamin, Emelia
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PMID: 27198950; PMCID: PMC4875564; DOI: 10.1016/j.sleep.2015.11.009;

Tsao CW, Lyass A, Larson MG, Levy D, Hamburg NM, Vita JA, Benjamin EJ, Mitchell GF, Vasan RS. Relation of Central Arterial Stiffness to Incident Heart Failure in the Community. J Am Heart Assoc. 2015 Nov; 4(11).View Related Profiles.

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PMID: 26597152; PMCID: PMC4845230; DOI: 10.1161/JAHA.115.002189;

Lieb W, Enserro DM, Sullivan LM, Vasan RS. Residual Cardiovascular Risk in Individuals on Blood Pressure-Lowering Treatment. J Am Heart Assoc. 2015 Nov; 4(11).View Related Profiles.

Sullivan, Lisa
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PMID: 26588944; PMCID: PMC4845218; DOI: 10.1161/JAHA.115.002155;

Pase MP, Beiser A, Aparicio H, DeCarli C, Vasan RS, Murabito J, Seshadri S. Interarm differences in systolic blood pressure and the risk of dementia and subclinical brain injury. Alzheimers Dement. 2016 Apr; 12(4):438-45.View Related Profiles.

Beiser, Alexa
Aparicio, Hugo
Murabito, Joanne
Seshadri, Sudha
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PMID: 26542262; PMCID: PMC4841714; DOI: 10.1016/j.jalz.2015.09.006;

Bis JC, Sitlani C, Irvin R, Avery CL, Smith AV, Sun F, Evans DS, Musani SK, Li X, Trompet S, Krijthe BP, Harris TB, Quibrera PM, Brody JA, Demissie S, Davis BR, Wiggins KL, Tranah GJ, Lange LA, Sotoodehnia N, Stott DJ, Franco OH, Launer LJ, Stürmer T, Taylor KD, Cupples LA, Eckfeldt JH, Smith NL, Liu Y, Wilson JG, Heckbert SR, Buckley BM, Ikram MA, Boerwinkle E, Chen YD, de Craen AJ, Uitterlinden AG, Rotter JI, Ford I, Hofman A, Sattar N, Slagboom PE, Westendorp RG, Gudnason V, Vasan RS, Lumley T, Cummings SR, Taylor HA, Post W, Jukema JW, Stricker BH, Whitsel EA, Psaty BM, Arnett D. Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium. PLoS One. 2015; 10(10):e0140496.View Related Profiles.

Sun, Fangui
Cupples, L
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PMID: 26516778; PMCID: PMC4627813; DOI: 10.1371/journal.pone.0140496;

Cheng S, McCabe EL, Larson MG, Merz AA, Osypiuk E, Lehman BT, Stantchev P, Aragam J, Solomon SD, Benjamin EJ, Vasan RS. Distinct Aspects of Left Ventricular Mechanical Function Are Differentially Associated With Cardiovascular Outcomes and All-Cause Mortality in the Community. J Am Heart Assoc. 2015 Oct; 4(10):e002071.View Related Profiles.

Benjamin, Emelia
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Ramachandran, Vasan

PMID: 26508740; PMCID: PMC4845131; DOI: 10.1161/JAHA.115.002071;

Rebholz CM, Grams ME, Lutsey PL, Hoofnagle AN, Misialek JR, Inker LA, Levey AS, Selvin E, Hsu CY, Kimmel PL, Vasan RS, Eckfeldt JH, Coresh J. Biomarkers of Vitamin D Status and Risk of ESRD. Am J Kidney Dis. 2016 Feb; 67(2):235-42. PMID: 26475393; PMCID: PMC4724452; DOI: 10.1053/j.ajkd.2015.08.026;

Delling FN, Rong J, Larson MG, Lehman B, Osypiuk E, Stantchev P, Slaugenhaupt SA, Benjamin EJ, Levine RA, Vasan RS. Response to Letter Regarding Article, "Familial Clustering of Mitral Valve Prolapse in the Community". Circulation. 2015 Oct 6; 132(14):e187-8.View Related Profiles.

Benjamin, Emelia
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PMID: 26438779; PMCID: PMC4620666; DOI: 10.1161/CIRCULATIONAHA.115.016788;

Andersson C, Vasan RS. Lipophilic Statins and Aldosterone Secretion: A Bridge Too Far? Circulation. 2015 Nov 10; 132(19):1783-5. PMID: 26432672; PMCID: PMC4974093; DOI: 10.1161/CIRCULATIONAHA.115.019130;

Andersson C, Lyass A, Larson MG, Robins SJ, Vasan RS. Low-density-lipoprotein cholesterol concentrations and risk of incident diabetes: epidemiological and genetic insights from the Framingham Heart Study. Diabetologia. 2015 Dec; 58(12):2774-80.View Related Profiles.

Larson, Martin
Robins, Sander
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PMID: 26409460; PMCID: PMC4631796; DOI: 10.1007/s00125-015-3762-x;

Foster MC, Coresh J, Bonventre JV, Sabbisetti VS, Waikar SS, Mifflin TE, Nelson RG, Grams M, Feldman HI, Vasan RS, Kimmel PL, Hsu CY, Liu KD. Urinary Biomarkers and Risk of ESRD in the Atherosclerosis Risk in Communities Study. Clin J Am Soc Nephrol. 2015 Nov 6; 10(11):1956-63.View Related Profiles.

Waikar, Sushrut
Ramachandran, Vasan

PMID: 26350438; PMCID: PMC4633784; DOI: 10.2215/CJN.02590315;

Saber H, Himali JJ, Shoamanesh A, Beiser A, Pikula A, Harris TB, Roubenoff R, Romero JR, Kase CS, Vasan RS, Seshadri S. Serum Leptin Levels and the Risk of Stroke: The Framingham Study. Stroke. 2015 Oct; 46(10):2881-5.View Related Profiles.

Beiser, Alexa
Shoamanesh, Ashkan
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Ramachandran, Vasan

PMID: 26337973; PMCID: PMC4589501; DOI: 10.1161/STROKEAHA.115.009463;

Nayor M, Vasan RS. Preventing heart failure: the role of physical activity. Curr Opin Cardiol. 2015 Sep; 30(5):543-50.View Related Profiles.

Nayor, Matthew
Ramachandran, Vasan

PMID: 26154074; PMCID: PMC4615715; DOI: 10.1097/HCO.0000000000000206;

Dina C, Bouatia-Naji N, Tucker N, Delling FN, Toomer K, Durst R, Perrocheau M, Fernandez-Friera L, Solis J, Le Tourneau T, Chen MH, Probst V, Bosse Y, Pibarot P, Zelenika D, Lathrop M, Hercberg S, Roussel R, Benjamin EJ, Bonnet F, Lo SH, Dolmatova E, Simonet F, Lecointe S, Kyndt F, Redon R, Le Marec H, Froguel P, Ellinor PT, Vasan RS, Bruneval P, Markwald RR, Norris RA, Milan DJ, Slaugenhaupt SA, Levine RA, Schott JJ, Hagege AA, Jeunemaitre X. Genetic association analyses highlight biological pathways underlying mitral valve prolapse. Nat Genet. 2015 Oct; 47(10):1206-11.View Related Profiles.

Benjamin, Emelia
Ramachandran, Vasan

PMID: 26301497; PMCID: PMC4773907; DOI: 10.1038/ng.3383;

Kenchaiah S, Vasan RS. Heart Failure in Women--Insights from the Framingham Heart Study. Cardiovasc Drugs Ther. 2015 Aug; 29(4):377-90.View Related Profiles.

Kenchaiah, Satish
Ramachandran, Vasan

PMID: 26245740; PMCID: PMC5303703; DOI: 10.1007/s10557-015-6599-0;

Rahman F, Wang N, Yin X, Ellinor PT, Lubitz SA, LeLorier PA, McManus DD, Sullivan LM, Seshadri S, Vasan RS, Benjamin EJ, Magnani JW. Atrial flutter: Clinical risk factors and adverse outcomes in the Framingham Heart Study. Heart Rhythm. 2016 Jan; 13(1):233-40.View Related Profiles.

Benjamin, Emelia
Rahman, Faisal
Magnani, Jared
Sullivan, Lisa
Seshadri, Sudha
Ramachandran, Vasan
Yin, Xiaoyan

PMID: 26226213; PMCID: PMC4698205; DOI: 10.1016/j.hrthm.2015.07.031;

Andersson C, Preis SR, Beiser A, DeCarli C, Wollert KC, Wang TJ, Januzzi JL, Vasan RS, Seshadri S. Associations of Circulating Growth Differentiation Factor-15 and ST2 Concentrations With Subclinical Vascular Brain Injury and Incident Stroke. Stroke. 2015 Sep; 46(9):2568-75.View Related Profiles.

Beiser, Alexa
Preis, Sarah
Seshadri, Sudha
Ramachandran, Vasan

PMID: 26219649; PMCID: PMC4550531; DOI: 10.1161/STROKEAHA.115.009026;

Jansen H, Loley C, Lieb W, Pencina MJ, Nelson CP, Kathiresan S, Peloso GM, Voight BF, Reilly MP, Assimes TL, Boerwinkle E, Hengstenberg C, Laaksonen R, McPherson R, Roberts R, Thorsteinsdottir U, Peters A, Gieger C, Rawal R, Thompson JR, König IR, Vasan RS, Erdmann J, Samani NJ, Schunkert H. Genetic variants primarily associated with type 2 diabetes are related to coronary artery disease risk. Atherosclerosis. 2015 Aug; 241(2):419-26.View Related Profiles.

Peloso, Gina
Pencina, Michael
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PMID: 26074316; PMCID: PMC4536952; DOI: 10.1016/j.atherosclerosis.2015.05.033;

Cheng S, Larson MG, McCabe EL, Murabito JM, Rhee EP, Ho JE, Jacques PF, Ghorbani A, Magnusson M, Souza AL, Deik AA, Pierce KA, Bullock K, O'Donnell CJ, Melander O, Clish CB, Vasan RS, Gerszten RE, Wang TJ. Erratum: Distinct metabolomic signatures are associated with longevity in humans. Nat Commun. 2015; 6:7317.View Related Profiles.

O'Donnell, Christopher
Murabito, Joanne
Larson, Martin
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PMID: 25993905; DOI: 10.1038/ncomms8317;

Long MT, Pedley A, Massaro JM, Hoffmann U, Esliger DW, Vasan RS, Fox CS, Murabito JM. Hepatic steatosis is associated with lower levels of physical activity measured via accelerometry. Obesity (Silver Spring). 2015 Jun; 23(6):1259-66.View Related Profiles.

Murabito, Joanne
Massaro, Joseph
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PMID: 25959049; PMCID: PMC4446168; DOI: 10.1002/oby.21058;

Schnabel RB, Yin X, Gona P, Larson MG, Beiser AS, McManus DD, Newton-Cheh C, Lubitz SA, Magnani JW, Ellinor PT, Seshadri S, Wolf PA, Vasan RS, Benjamin EJ, Levy D. 50 year trends in atrial fibrillation prevalence, incidence, risk factors, and mortality in the Framingham Heart Study: a cohort study. Lancet. 2015 Jul 11; 386(9989):154-62.View Related Profiles.

Beiser, Alexa
Benjamin, Emelia
Magnani, Jared
Larson, Martin
Wolf, Philip
Seshadri, Sudha
Ramachandran, Vasan

PMID: 25960110; PMCID: PMC4553037; DOI: 10.1016/S0140-6736(14)61774-8;

Andersson C, Enserro D, Larson MG, Xanthakis V, Vasan RS. Implications of the US cholesterol guidelines on eligibility for statin therapy in the community: comparison of observed and predicted risks in the Framingham Heart Study Offspring Cohort. J Am Heart Assoc. 2015 Apr; 4(4).View Related Profiles.

Larson, Martin
Xanthakis, Vanessa
Ramachandran, Vasan

PMID: 25888372; PMCID: PMC4579932; DOI: 10.1161/JAHA.115.001888;

Sauder KA, Proctor DN, Chow M, Troy LM, Wang N, Vita JA, Vasan RS, Mitchell GF, Jacques PF, Hamburg NM, West SG. Endothelial function, arterial stiffness and adherence to the 2010 Dietary Guidelines for Americans: a cross-sectional analysis. Br J Nutr. 2015 Jun 14; 113(11):1773-81.View Related Profiles.

Hamburg, Naomi
Ramachandran, Vasan

PMID: 25885520; PMCID: PMC4466070; DOI: 10.1017/S0007114515000859;

Huan T, Meng Q, Saleh MA, Norlander AE, Joehanes R, Zhu J, Chen BH, Zhang B, Johnson AD, Ying S, Courchesne P, Raghavachari N, Wang R, Liu P, O'Donnell CJ, Vasan R, Munson PJ, Madhur MS, Harrison DG, Yang X, Levy D. Integrative network analysis reveals molecular mechanisms of blood pressure regulation. Mol Syst Biol. 2015 Jan; 11(1):799.View Related Profiles.

O'Donnell, Christopher
Ramachandran, Vasan

PMID: 25882670; PMCID: PMC4422556; DOI: 10.15252/msb.20145399;

Cheng S, Larson MG, McCabe EL, Murabito JM, Rhee EP, Ho JE, Jacques PF, Ghorbani A, Magnusson M, Souza AL, Deik AA, Pierce KA, Bullock K, O'Donnell CJ, Melander O, Clish CB, Vasan RS, Gerszten RE, Wang TJ. Distinct metabolomic signatures are associated with longevity in humans. Nat Commun. 2015; 6:6791.View Related Profiles.

O'Donnell, Christopher
Ho, Jennifer
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Larson, Martin
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PMID: 25864806; PMCID: PMC4396657; DOI: 10.1038/ncomms7791;

Fontes JD, Rahman F, Lacey S, Larson MG, Vasan RS, Benjamin EJ, Harris WS, Robins SJ. Red blood cell fatty acids and biomarkers of inflammation: a cross-sectional study in a community-based cohort. Atherosclerosis. 2015 Jun; 240(2):431-6.View Related Profiles.

Benjamin, Emelia
Rahman, Faisal
Larson, Martin
Robins, Sander
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PMID: 25897795; PMCID: PMC4511480; DOI: 10.1016/j.atherosclerosis.2015.03.043;

Andersson C, Lyass A, Larson MG, Spartano NL, Vita JA, Benjamin EJ, Murabito JM, Esliger DW, Blease SJ, Hamburg NM, Mitchell GF, Vasan RS. Physical activity measured by accelerometry and its associations with cardiac structure and vascular function in young and middle-aged adults. J Am Heart Assoc. 2015 Mar; 4(3):e001528.View Related Profiles.

Benjamin, Emelia
Murabito, Joanne
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Larson, Martin
Hamburg, Naomi
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PMID: 25792127; PMCID: PMC4392434; DOI: 10.1161/JAHA.114.001528;

Huan T, Esko T, Peters MJ, Pilling LC, Schramm K, Schurmann C, Chen BH, Liu C, Joehanes R, Johnson AD, Yao C, Ying SX, Courchesne P, Milani L, Raghavachari N, Wang R, Liu P, Reinmaa E, Dehghan A, Hofman A, Uitterlinden AG, Hernandez DG, Bandinelli S, Singleton A, Melzer D, Metspalu A, Carstensen M, Grallert H, Herder C, Meitinger T, Peters A, Roden M, Waldenberger M, Dörr M, Felix SB, Zeller T, Vasan R, O'Donnell CJ, Munson PJ, Yang X, Prokisch H, Völker U, van Meurs JB, Ferrucci L, Levy D. A meta-analysis of gene expression signatures of blood pressure and hypertension. PLoS Genet. 2015 Mar; 11(3):e1005035.View Related Profiles.

O'Donnell, Christopher
Liu, Chunyu
Ramachandran, Vasan

PMID: 25785607; PMCID: PMC4365001; DOI: 10.1371/journal.pgen.1005035;

Lubitz SA, Yin X, Rienstra M, Schnabel RB, Walkey AJ, Magnani JW, Rahman F, McManus DD, Tadros TM, Levy D, Vasan RS, Larson MG, Ellinor PT, Benjamin EJ. Long-term outcomes of secondary atrial fibrillation in the community: the Framingham Heart Study. Circulation. 2015 May 12; 131(19):1648-55.View Related Profiles.

Walkey, Allan
Levy, Daniel
Benjamin, Emelia
Rahman, Faisal
Magnani, Jared
Larson, Martin
Ramachandran, Vasan
Yin, Xiaoyan

PMID: 25769640; PMCID: PMC4430386; DOI: 10.1161/CIRCULATIONAHA.114.014058;

Xanthakis V, Sung JH, Samdarshi TE, Hill AN, Musani SK, Sims M, Ghraibeh KA, Liebson PR, Taylor HA, Vasan RS, Fox ER. Relations between subclinical disease markers and type 2 diabetes, metabolic syndrome, and incident cardiovascular disease: the Jackson Heart Study. Diabetes Care. 2015 Jun; 38(6):1082-8.View Related Profiles.

Xanthakis, Vanessa
Ramachandran, Vasan

PMID: 25765357; PMCID: PMC4439537; DOI: 10.2337/dc14-2460;

Foster MC, Inker LA, Hsu CY, Eckfeldt JH, Levey AS, Pavkov ME, Myers BD, Bennett PH, Kimmel PL, Vasan RS, Coresh J, Nelson RG. Filtration markers as predictors of ESRD and mortality in Southwestern American Indians with type 2 diabetes. Am J Kidney Dis. 2015 Jul; 66(1):75-83. PMID: 25773485; PMCID: PMC4485524; DOI: 10.1053/j.ajkd.2015.01.013;

Kaess BM, Preis SR, Lieb W, Beiser AS, Yang Q, Chen TC, Hengstenberg C, Erdmann J, Schunkert H, Seshadri S, Vasan RS, Assimes TL, Deloukas P, Holm H, Kathiresan S, König IR, McPherson R, Reilly MP, Roberts R, Samani NJ, Stewart AF. Circulating brain-derived neurotrophic factor concentrations and the risk of cardiovascular disease in the community. J Am Heart Assoc. 2015 Mar; 4(3):e001544.View Related Profiles.

Beiser, Alexa
Kaess, Bernhard
Yang, Qiong
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Chen, Tai
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PMID: 25762803; PMCID: PMC4392437; DOI: 10.1161/JAHA.114.001544;

Long MT, Wang N, Larson MG, Mitchell GF, Palmisano J, Vasan RS, Hoffmann U, Speliotes EK, Vita JA, Benjamin EJ, Fox CS, Hamburg NM. Nonalcoholic fatty liver disease and vascular function: cross-sectional analysis in the Framingham heart study. Arterioscler Thromb Vasc Biol. 2015 May; 35(5):1284-91.View Related Profiles.

Benjamin, Emelia
Vita, Joseph
Larson, Martin
Long, Michelle
Hamburg, Naomi
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PMID: 25745056; PMCID: PMC4520415; DOI: 10.1161/ATVBAHA.114.305200;

Hsu CY, Ballard S, Batlle D, Bonventre JV, Böttinger EP, Feldman HI, Klein JB, Coresh J, Eckfeldt JH, Inker LA, Kimmel PL, Kusek JW, Liu KD, Mauer M, Mifflin TE, Molitch ME, Nelsestuen GL, Rebholz CM, Rovin BH, Sabbisetti VS, Van Eyk JE, Vasan RS, Waikar SS, Whitehead KM, Nelson RG. Cross-Disciplinary Biomarkers Research: Lessons Learned by the CKD Biomarkers Consortium. Clin J Am Soc Nephrol. 2015 May 7; 10(5):894-902.View Related Profiles.

Waikar, Sushrut
Ramachandran, Vasan

PMID: 25739849; PMCID: PMC4422251; DOI: 10.2215/CJN.11541114;

Vasan RS, Folsom AR. Invited commentary: future of population studies--defining research priorities and processes. Am J Epidemiol. 2015 Mar 15; 181(6):369-71. PMID: 25743322; PMCID: PMC4380021; DOI: 10.1093/aje/kwv012;

Murabito JM, Pedley A, Massaro JM, Vasan RS, Esliger D, Blease SJ, Hoffman U, Fox CS. Moderate-to-vigorous physical activity with accelerometry is associated with visceral adipose tissue in adults. J Am Heart Assoc. 2015 Mar; 4(3):e001379.View Related Profiles.

Murabito, Joanne
Massaro, Joseph
Ramachandran, Vasan

PMID: 25736442; PMCID: PMC4392428; DOI: 10.1161/JAHA.114.001379;

Shungin D, Winkler TW, Croteau-Chonka DC, Ferreira T, Locke AE, Mägi R, Strawbridge RJ, Pers TH, Fischer K, Justice AE, Workalemahu T, Wu JM, Buchkovich ML, Heard-Costa NL, Roman TS, Drong AW, Song C, Gustafsson S, Day FR, Esko T, Fall T, Kutalik Z, Luan J, Randall JC, Scherag A, Vedantam S, Wood AR, Chen J, Fehrmann R, Karjalainen J, Kahali B, Liu CT, Schmidt EM, Absher D, Amin N, Anderson D, Beekman M, Bragg-Gresham JL, Buyske S, Demirkan A, Ehret GB, Feitosa MF, Goel A, Jackson AU, Johnson T, Kleber ME, Kristiansson K, Mangino M, Mateo Leach I, Medina-Gomez C, Palmer CD, Pasko D, Pechlivanis S, Peters MJ, Prokopenko I, Stancáková A, Ju Sung Y, Tanaka T, Teumer A, Van Vliet-Ostaptchouk JV, Yengo L, Zhang W, Albrecht E, Ärnlöv J, Arscott GM, Bandinelli S, Barrett A, Bellis C, Bennett AJ, Berne C, Blüher M, Böhringer S, Bonnet F, Böttcher Y, Bruinenberg M, Carba DB, Caspersen IH, Clarke R, Daw EW, Deelen J, Deelman E, Delgado G, Doney AS, Eklund N, Erdos MR, Estrada K, Eury E, Friedrich N, Garcia ME, Giedraitis V, Gigante B, Go AS, Golay A, Grallert H, Grammer TB, Gräßler J, Grewal J, Groves CJ, Haller T, Hallmans G, Hartman CA, Hassinen M, Hayward C, Heikkilä K, Herzig KH, Helmer Q, Hillege HL, Holmen O, Hunt SC, Isaacs A, Ittermann T, James AL, Johansson I, Juliusdottir T, Kalafati IP, Kinnunen L, Koenig W, Kooner IK, Kratzer W, Lamina C, Leander K, Lee NR, Lichtner P, Lind L, Lindström J, Lobbens S, Lorentzon M, Mach F, Magnusson PK, Mahajan A, McArdle WL, Menni C, Merger S, Mihailov E, Milani L, Mills R, Moayyeri A, Monda KL, Mooijaart SP, Mühleisen TW, Mulas A, Müller G, Müller-Nurasyid M, Nagaraja R, Nalls MA, Narisu N, Glorioso N, Nolte IM, Olden M, Rayner NW, Renstrom F, Ried JS, Robertson NR, Rose LM, Sanna S, Scharnagl H, Scholtens S, Sennblad B, Seufferlein T, Sitlani CM, Vernon Smith A, Stirrups K, Stringham HM, Sundström J, Swertz MA, Swift AJ, Syvänen AC, Tayo BO, Thorand B, Thorleifsson G, Tomaschitz A, Troffa C, van Oort FV, Verweij N, Vonk JM, Waite LL, Wennauer R, Wilsgaard T, Wojczynski MK, Wong A, Zhang Q, Hua Zhao J, Brennan EP, Choi M, Eriksson P, Folkersen L, Franco-Cereceda A, Gharavi AG, Hedman ÅK, Hivert MF, Huang J, Kanoni S, Karpe F, Keildson S, Kiryluk K, Liang L, Lifton RP, Ma B, McKnight AJ, McPherson R, Metspalu A, Min JL, Moffatt MF, Montgomery GW, Murabito JM, Nicholson G, Nyholt DR, Olsson C, Perry JR, Reinmaa E, Salem RM, Sandholm N, Schadt EE, Scott RA, Stolk L, Vallejo EE, Westra HJ, Zondervan KT, Amouyel P, Arveiler D, Bakker SJ, Beilby J, Bergman RN, Blangero J, Brown MJ, Burnier M, Campbell H, Chakravarti A, Chines PS, Claudi-Boehm S, Collins FS, Crawford DC, Danesh J, de Faire U, de Geus EJ, Dörr M, Erbel R, Eriksson JG, Farrall M, Ferrannini E, Ferrières J, Forouhi NG, Forrester T, Franco OH, Gansevoort RT, Gieger C, Gudnason V, Haiman CA, Harris TB, Hattersley AT, Heliövaara M, Hicks AA, Hingorani AD, Hoffmann W, Hofman A, Homuth G, Humphries SE, Hyppönen E, Illig T, Jarvelin MR, Johansen B, Jousilahti P, Jula AM, Kaprio J, Kee F, Keinanen-Kiukaanniemi SM, Kooner JS, Kooperberg C, Kovacs P, Kraja AT, Kumari M, Kuulasmaa K, Kuusisto J, Lakka TA, Langenberg C, Le Marchand L, Lehtimäki T, Lyssenko V, Männistö S, Marette A, Matise TC, McKenzie CA, McKnight B, Musk AW, Möhlenkamp S, Morris AD, Nelis M, Ohlsson C, Oldehinkel AJ, Ong KK, Palmer LJ, Penninx BW, Peters A, Pramstaller PP, Raitakari OT, Rankinen T, Rao DC, Rice TK, Ridker PM, Ritchie MD, Rudan I, Salomaa V, Samani NJ, Saramies J, Sarzynski MA, Schwarz PE, Shuldiner AR, Staessen JA, Steinthorsdottir V, Stolk RP, Strauch K, Tönjes A, Tremblay A, Tremoli E, Vohl MC, Völker U, Vollenweider P, Wilson JF, Witteman JC, Adair LS, Bochud M, Boehm BO, Bornstein SR, Bouchard C, Cauchi S, Caulfield MJ, Chambers JC, Chasman DI, Cooper RS, Dedoussis G, Ferrucci L, Froguel P, Grabe HJ, Hamsten A, Hui J, Hveem K, Jöckel KH, Kivimaki M, Kuh D, Laakso M, Liu Y, März W, Munroe PB, Njølstad I, Oostra BA, Palmer CN, Pedersen NL, Perola M, et al. NeView Related Profiles.

Liu, Ching-Ti
Murabito, Joanne
Cupples, L
Heard-Costa, Nancy
Ramachandran, Vasan

PMID: 25673412; PMCID: PMC4338562; DOI: 10.1038/nature14132;

Locke AE, Kahali B, Berndt SI, Justice AE, Pers TH, Day FR, Powell C, Vedantam S, Buchkovich ML, Yang J, Croteau-Chonka DC, Esko T, Fall T, Ferreira T, Gustafsson S, Kutalik Z, Luan J, Mägi R, Randall JC, Winkler TW, Wood AR, Workalemahu T, Faul JD, Smith JA, Hua Zhao J, Zhao W, Chen J, Fehrmann R, Hedman ÅK, Karjalainen J, Schmidt EM, Absher D, Amin N, Anderson D, Beekman M, Bolton JL, Bragg-Gresham JL, Buyske S, Demirkan A, Deng G, Ehret GB, Feenstra B, Feitosa MF, Fischer K, Goel A, Gong J, Jackson AU, Kanoni S, Kleber ME, Kristiansson K, Lim U, Lotay V, Mangino M, Mateo Leach I, Medina-Gomez C, Medland SE, Nalls MA, Palmer CD, Pasko D, Pechlivanis S, Peters MJ, Prokopenko I, Shungin D, Stancáková A, Strawbridge RJ, Ju Sung Y, Tanaka T, Teumer A, Trompet S, van der Laan SW, van Setten J, Van Vliet-Ostaptchouk JV, Wang Z, Yengo L, Zhang W, Isaacs A, Albrecht E, Ärnlöv J, Arscott GM, Attwood AP, Bandinelli S, Barrett A, Bas IN, Bellis C, Bennett AJ, Berne C, Blagieva R, Blüher M, Böhringer S, Bonnycastle LL, Böttcher Y, Boyd HA, Bruinenberg M, Caspersen IH, Ida Chen YD, Clarke R, Daw EW, de Craen AJ, Delgado G, Dimitriou M, Doney AS, Eklund N, Estrada K, Eury E, Folkersen L, Fraser RM, Garcia ME, Geller F, Giedraitis V, Gigante B, Go AS, Golay A, Goodall AH, Gordon SD, Gorski M, Grabe HJ, Grallert H, Grammer TB, Gräßler J, Grönberg H, Groves CJ, Gusto G, Haessler J, Hall P, Haller T, Hallmans G, Hartman CA, Hassinen M, Hayward C, Heard-Costa NL, Helmer Q, Hengstenberg C, Holmen O, Hottenga JJ, James AL, Jeff JM, Johansson Å, Jolley J, Juliusdottir T, Kinnunen L, Koenig W, Koskenvuo M, Kratzer W, Laitinen J, Lamina C, Leander K, Lee NR, Lichtner P, Lind L, Lindström J, Sin Lo K, Lobbens S, Lorbeer R, Lu Y, Mach F, Magnusson PK, Mahajan A, McArdle WL, McLachlan S, Menni C, Merger S, Mihailov E, Milani L, Moayyeri A, Monda KL, Morken MA, Mulas A, Müller G, Müller-Nurasyid M, Musk AW, Nagaraja R, Nöthen MM, Nolte IM, Pilz S, Rayner NW, Renstrom F, Rettig R, Ried JS, Ripke S, Robertson NR, Rose LM, Sanna S, Scharnagl H, Scholtens S, Schumacher FR, Scott WR, Seufferlein T, Shi J, Vernon Smith A, Smolonska J, Stanton AV, Steinthorsdottir V, Stirrups K, Stringham HM, Sundström J, Swertz MA, Swift AJ, Syvänen AC, Tan ST, Tayo BO, Thorand B, Thorleifsson G, Tyrer JP, Uh HW, Vandenput L, Verhulst FC, Vermeulen SH, Verweij N, Vonk JM, Waite LL, Warren HR, Waterworth D, Weedon MN, Wilkens LR, Willenborg C, Wilsgaard T, Wojczynski MK, Wong A, Wright AF, Zhang Q, Brennan EP, Choi M, Dastani Z, Drong AW, Eriksson P, Franco-Cereceda A, Gådin JR, Gharavi AG, Goddard ME, Handsaker RE, Huang J, Karpe F, Kathiresan S, Keildson S, Kiryluk K, Kubo M, Lee JY, Liang L, Lifton RP, Ma B, McCarroll SA, McKnight AJ, Min JL, Moffatt MF, Montgomery GW, Murabito JM, Nicholson G, Nyholt DR, Okada Y, Perry JR, Dorajoo R, Reinmaa E, Salem RM, Sandholm N, Scott RA, Stolk L, Takahashi A, Tanaka T, Van't Hooft FM, Vinkhuyzen AA, Westra HJ, Zheng W, Zondervan KT, Heath AC, Arveiler D, Bakker SJ, Beilby J, Bergman RN, Blangero J, Bovet P, Campbell H, Caulfield MJ, Cesana G, Chakravarti A, Chasman DI, Chines PS, Collins FS, Crawford DC, Cupples LA, Cusi D, Danesh J, de Faire U, den Ruijter HM, Dominiczak AF, Erbel R, Erdmann J, Eriksson JG, Farrall M, Felix SB, Ferrannini E, Ferrières J, Ford I, Forouhi NG, Forrester T, Franco OH, Gansevoort RT, Gejman PV, Gieger C, Gottesman O, Gudnason V, Gyllensten U, Hall AS, Harris TB, Hattersley AT, Hicks AA, Hindorff LA, Hingorani AD, Hofman A, Homuth G, Hovingh GK, Humphries SE, Hunt SC, Hyppönen E, Illig T, Jacobs KB, Jarvelin MR, Jöckel KH, Johansen B, Jousilahti P, Jukema JW, Jula AM, Kaprio J, Kastelein JJ, Keinanen-Kiukaanniemi SM, Kiemeney LA, Knekt P, Kooner JS, Kooperberg C, Kovacs P, Kraja AT, Kumari M, Kuusisto J, Lakka TA, Langenberg C, Le Marchand L, Lehtimäki T, Lyssenko V, Männistö S, Marette A, Matise TC, McKenzie CA, McKnight B, Moll FL, Morris AD, Morris AP, Murray JC, Nelis M, Ohlsson C, et al. Genetic stuView Related Profiles.

Murabito, Joanne
Cupples, L
Heard-Costa, Nancy
Ramachandran, Vasan

PMID: 25673413; PMCID: PMC4382211; DOI: 10.1038/nature14177;

Fox ER, Musani SK, Samdarshi TE, Taylor JK, Beard WL, Sarpong DF, Xanthakis V, McClendon EE, Liebson PR, Skelton TN, Butler KR, Mosley TH, Taylor H, Vasan RS. Clinical correlates and prognostic significance of change in standardized left ventricular mass in a community-based cohort of African Americans. J Am Heart Assoc. 2015 Feb; 4(2).View Related Profiles.

Xanthakis, Vanessa
Ramachandran, Vasan

PMID: 25655570; PMCID: PMC4345860; DOI: 10.1161/JAHA.114.001224;

Fufaa GD, Weil EJ, Nelson RG, Hanson RL, Knowler WC, Rovin BH, Wu H, Klein JB, Mifflin TE, Feldman HI, Vasan RS, Kimmel PL, Kusek JW, Mauer M. Urinary monocyte chemoattractant protein-1 and hepcidin and early diabetic nephropathy lesions in type 1 diabetes mellitus. Nephrol Dial Transplant. 2015 Apr; 30(4):599-606. PMID: 25648911; PMCID: PMC4402379; DOI: 10.1093/ndt/gfv012;

Delling FN, Vasan RS. Mitral valve prolapse and glaucoma: a 'floppy' perception? Heart. 2015 Apr; 101(8):584-5. PMID: 25637370; DOI: 10.1136/heartjnl-2014-307229;

Pencina MJ, D'Agostino RB, Zdrojewski T, Williams K, Thanassoulis G, Furberg CD, Peterson ED, Vasan RS, Sniderman AD. Apolipoprotein B improves risk assessment of future coronary heart disease in the Framingham Heart Study beyond LDL-C and non-HDL-C. Eur J Prev Cardiol. 2015 Oct; 22(10):1321-7.View Related Profiles.

Pencina, Michael
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 25633587; DOI: 10.1177/2047487315569411;

Shoamanesh A, Preis SR, Beiser AS, Vasan RS, Benjamin EJ, Kase CS, Wolf PA, DeCarli C, Romero JR, Seshadri S. Inflammatory biomarkers, cerebral microbleeds, and small vessel disease: Framingham Heart Study. Neurology. 2015 Feb 24; 84(8):825-32.View Related Profiles.

Beiser, Alexa
Shoamanesh, Ashkan
Kase, Carlos
Benjamin, Emelia
Romero, Jose
Wolf, Philip
Preis, Sarah
Seshadri, Sudha
Ramachandran, Vasan

PMID: 25632086; PMCID: PMC4345647; DOI: 10.1212/WNL.0000000000001279;

Sud M, Wang X, Austin PC, Lipscombe LL, Newton GE, Tu JV, Vasan RS, Lee DS. Presentation blood glucose and death, hospitalization, and future diabetes risk in patients with acute heart failure syndromes. Eur Heart J. 2015 Apr 14; 36(15):924-31. PMID: 25572328; PMCID: PMC6371700; DOI: 10.1093/eurheartj/ehu462;

Würtz P, Havulinna AS, Soininen P, Tynkkynen T, Prieto-Merino D, Tillin T, Ghorbani A, Artati A, Wang Q, Tiainen M, Kangas AJ, Kettunen J, Kaikkonen J, Mikkilä V, Jula A, Kähönen M, Lehtimäki T, Lawlor DA, Gaunt TR, Hughes AD, Sattar N, Illig T, Adamski J, Wang TJ, Perola M, Ripatti S, Vasan RS, Raitakari OT, Gerszten RE, Casas JP, Chaturvedi N, Ala-Korpela M, Salomaa V. Metabolite profiling and cardiovascular event risk: a prospective study of 3 population-based cohorts. Circulation. 2015 Mar 3; 131(9):774-85. PMID: 25573147; PMCID: PMC4351161; DOI: 10.1161/CIRCULATIONAHA.114.013116;

Musani SK, Fox ER, Kraja A, Bidulescu A, Lieb W, Lin H, Beecham A, Chen MH, Felix JF, Fox CS, Kao WH, Kardia SL, Liu CT, Nalls MA, Rundek T, Sacco RL, Smith J, Sun YV, Wilson G, Zhang Z, Mosley TH, Taylor HA, Vasan RS. Genome-wide association analysis of plasma B-type natriuretic peptide in blacks: the Jackson Heart Study. Circ Cardiovasc Genet. 2015 Feb; 8(1):122-30.View Related Profiles.

Liu, Ching-Ti
Lin, Honghuang
Ramachandran, Vasan

PMID: 25561047; PMCID: PMC4426827; DOI: 10.1161/CIRCGENETICS.114.000900;

Rosenquist KJ, Massaro JM, Pedley A, Long MT, Kreger BE, Vasan RS, Murabito JM, Hoffmann U, Fox CS. Fat quality and incident cardiovascular disease, all-cause mortality, and cancer mortality. J Clin Endocrinol Metab. 2015 Jan; 100(1):227-34.View Related Profiles.

Kreger, Bernard
Murabito, Joanne
Massaro, Joseph
Long, Michelle
Ramachandran, Vasan

PMID: 25226289; PMCID: PMC5399496; DOI: 10.1210/jc.2013-4296;

Nayor M, Vasan RS. Endogenous carbon monoxide and cardiometabolic risk: can measuring exhaled carbon monoxide be used to refine cardiometabolic risk assessment? Future Cardiol. 2015; 11(1):9-12.View Related Profiles.

Nayor, Matthew
Ramachandran, Vasan

PMID: 25606696; DOI: 10.2217/fca.14.78;

Lieb W, Chen MH, Larson MG, Safa R, Teumer A, Baumeister SE, Lin H, Smith HM, Koch M, Lorbeer R, Völker U, Nauck M, Völzke H, Wallaschofski H, Sawyer DB, Vasan RS. Genome-wide association study for endothelial growth factors. Circ Cardiovasc Genet. 2015 Apr; 8(2):389-97.View Related Profiles.

Lin, Honghuang
Larson, Martin
Ramachandran, Vasan

PMID: 25552591; PMCID: PMC4406801; DOI: 10.1161/CIRCGENETICS.114.000597;

White IR, Rapsomaniki E. Covariate-adjusted measures of discrimination for survival data. Biom J. 2015 Jul; 57(4):592-613. PMID: 25530064; PMCID: PMC4666552; DOI: 10.1002/bimj.201400061;

Kaess BM, Harris WS, Lacey S, Larson MG, Hamburg NM, Vita JA, Robins SJ, Benjamin EJ, Mitchell GF, Vasan RS. The relation of red blood cell fatty acids with vascular stiffness, cardiac structure and left ventricular function: the Framingham Heart Study. Vasc Med. 2015 Feb; 20(1):5-13.View Related Profiles.

Kaess, Bernhard
Benjamin, Emelia
Vita, Joseph
Larson, Martin
Hamburg, Naomi
Robins, Sander
Ramachandran, Vasan

PMID: 25520318; DOI: 10.1177/1358863X14560808;

Lieb W, Chen MH, Teumer A, de Boer RA, Lin H, Fox ER, Musani SK, Wilson JG, Wang TJ, Völzke H, Petersen AK, Meisinger C, Nauck M, Schlesinger S, Li Y, Menard J, Hercberg S, Wichmann HE, Völker U, Rawal R, Bidlingmaier M, Hannemann A, Dörr M, Rettig R, van Gilst WH, van Veldhuisen DJ, Bakker SJ, Navis G, Wallaschofski H, Meneton P, van der Harst P, Reincke M, Vasan RS. Genome-wide meta-analyses of plasma renin activity and concentration reveal association with the kininogen 1 and prekallikrein genes. Circ Cardiovasc Genet. 2015 Feb; 8(1):131-40.View Related Profiles.

Lin, Honghuang
Ramachandran, Vasan

PMID: 25477429; PMCID: PMC4354880; DOI: 10.1161/CIRCGENETICS.114.000613;

Deo RC, Musso G, Tasan M, Tang P, Poon A, Yuan C, Felix JF, Vasan RS, Beroukhim R, De Marco T, Kwok PY, MacRae CA, Roth FP. Prioritizing causal disease genes using unbiased genomic features. Genome Biol. 2014; 15(12):534. PMID: 25633252; PMCID: PMC4279789; DOI: 10.1186/s13059-014-0534-8;

Tintle NL, Pottala JV, Lacey S, Ramachandran V, Westra J, Rogers A, Clark J, Olthoff B, Larson M, Harris W, Shearer GC. A genome-wide association study of saturated, mono- and polyunsaturated red blood cell fatty acids in the Framingham Heart Offspring Study. Prostaglandins Leukot Essent Fatty Acids. 2015 Mar; 94:65-72.View Related Profiles.

Larson, Martin
Ramachandran, Vasan

PMID: 25500335; PMCID: PMC4339483; DOI: 10.1016/j.plefa.2014.11.007;

Andersson C, Vasan RS. Compiling the complement of genes implicated in coronary artery disease. Circ Cardiovasc Genet. 2014 Dec; 7(6):738-40. PMID: 25516622; DOI: 10.1161/CIRCGENETICS.114.000909;

Cheng S, McCabe EL, Larson MG, Chen MH, Osypiuk E, Lehman BT, Stantchev P, Aragam J, Solomon SD, Benjamin EJ, Vasan RS. Left ventricular mechanical function: clinical correlates, heritability, and association with parental heart failure. Eur J Heart Fail. 2015 Jan; 17(1):44-50.View Related Profiles.

Benjamin, Emelia
Osypiuk, Ewa
Aragam, Jayashri
Larson, Martin
Ramachandran, Vasan

PMID: 25445300; PMCID: PMC5467740; DOI: 10.1002/ejhf.202;

Franklin SS, Gokhale SS, Chow VH, Larson MG, Levy D, Vasan RS, Mitchell GF, Wong ND. Does low diastolic blood pressure contribute to the risk of recurrent hypertensive cardiovascular disease events? The Framingham Heart Study. Hypertension. 2015 Feb; 65(2):299-305.View Related Profiles.

Levy, Daniel
Larson, Martin
Ramachandran, Vasan

PMID: 25421982; DOI: 10.1161/HYPERTENSIONAHA.114.04581;

Cooper LL, Rong J, Benjamin EJ, Larson MG, Levy D, Vita JA, Hamburg NM, Vasan RS, Mitchell GF. Components of hemodynamic load and cardiovascular events: the Framingham Heart Study. Circulation. 2015 Jan 27; 131(4):354-61; discussion 361.View Related Profiles.

Levy, Daniel
Benjamin, Emelia
Vita, Joseph
Larson, Martin
Hamburg, Naomi
Ramachandran, Vasan

PMID: 25416177; PMCID: PMC4308473; DOI: 10.1161/CIRCULATIONAHA.114.011357;

Benjamin I, Brown N, Burke G, Correa A, Houser SR, Jones DW, Loscalzo J, Vasan RS, Whitman GR. American Heart Association Cardiovascular Genome-Phenome Study: foundational basis and program. Circulation. 2015 Jan 6; 131(1):100-12. PMID: 25411155; PMCID: PMC4286232; DOI: 10.1161/CIRCULATIONAHA.114.014190;

Tsao CW, Vasan RS. Cardiovascular endocrinology: Growth hormone in CVD prediction--a tall order? Nat Rev Endocrinol. 2015 Jan; 11(1):11-3. PMID: 25404017; DOI: 10.1038/nrendo.2014.204;

Liu C, Dupuis J, Larson MG, Cupples LA, Ordovas JM, Vasan RS, Meigs JB, Jacques PF, Levy D. Revisiting heritability accounting for shared environmental effects and maternal inheritance. Hum Genet. 2015 Feb; 134(2):169-79.View Related Profiles.

Liu, Chunyu
Dupuis, Josee
Cupples, L
Larson, Martin
Ramachandran, Vasan

PMID: 25381465; PMCID: PMC4303043; DOI: 10.1007/s00439-014-1505-6;

Andersson C, Gislason GH, Hlatky MA, Søndergaard KB, Pallisgaard J, Smith JG, Vasan RS, Larson MG, Jensen PF, Køber L, Torp-Pedersen C. A risk score for predicting 30-day mortality in heart failure patients undergoing non-cardiac surgery. Eur J Heart Fail. 2014 Dec; 16(12):1310-6.View Related Profiles.

Larson, Martin
Ramachandran, Vasan

PMID: 25359203; DOI: 10.1002/ejhf.182;

Delling FN, Rong J, Larson MG, Lehman B, Osypiuk E, Stantchev P, Slaugenhaupt SA, Benjamin EJ, Levine RA, Vasan RS. Familial clustering of mitral valve prolapse in the community. Circulation. 2015 Jan 20; 131(3):263-8.View Related Profiles.

Benjamin, Emelia
Osypiuk, Ewa
Rong, Jian
Larson, Martin
Ramachandran, Vasan

PMID: 25361552; PMCID: PMC4301989; DOI: 10.1161/CIRCULATIONAHA.114.012594;

Postmus I, Trompet S, Deshmukh HA, Barnes MR, Li X, Warren HR, Chasman DI, Zhou K, Arsenault BJ, Donnelly LA, Wiggins KL, Avery CL, Griffin P, Feng Q, Taylor KD, Li G, Evans DS, Smith AV, de Keyser CE, Johnson AD, de Craen AJ, Stott DJ, Buckley BM, Ford I, Westendorp RG, Slagboom PE, Sattar N, Munroe PB, Sever P, Poulter N, Stanton A, Shields DC, O'Brien E, Shaw-Hawkins S, Chen YD, Nickerson DA, Smith JD, Dubé MP, Boekholdt SM, Hovingh GK, Kastelein JJ, McKeigue PM, Betteridge J, Neil A, Durrington PN, Doney A, Carr F, Morris A, McCarthy MI, Groop L, Ahlqvist E, Bis JC, Rice K, Smith NL, Lumley T, Whitsel EA, Stürmer T, Boerwinkle E, Ngwa JS, O'Donnell CJ, Vasan RS, Wei WQ, Wilke RA, Liu CT, Sun F, Guo X, Heckbert SR, Post W, Sotoodehnia N, Arnold AM, Stafford JM, Ding J, Herrington DM, Kritchevsky SB, Eiriksdottir G, Launer LJ, Harris TB, Chu AY, Giulianini F, MacFadyen JG, Barratt BJ, Nyberg F, Stricker BH, Uitterlinden AG, Hofman A, Rivadeneira F, Emilsson V, Franco OH, Ridker PM, Gudnason V, Liu Y, Denny JC, Ballantyne CM, Rotter JI, Adrienne Cupples L, Psaty BM, Palmer CN, Tardif JC, Colhoun HM, Hitman G, Krauss RM, Wouter Jukema J, Caulfield MJ. Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins. Nat Commun. 2014; 5:5068.View Related Profiles.

Liu, Ching-Ti
O'Donnell, Christopher
Sun, Fangui
Ramachandran, Vasan

PMID: 25350695; PMCID: PMC4220464; DOI: 10.1038/ncomms6068;

Andersson C, Sullivan L, Benjamin EJ, Aragam J, Jacques P, Cheng S, Vasan RS. Association of soda consumption with subclinical cardiac remodeling in the Framingham heart study. Metabolism. 2015 Feb; 64(2):208-12.View Related Profiles.

Benjamin, Emelia
Aragam, Jayashri
Sullivan, Lisa
Ramachandran, Vasan

PMID: 25456096; PMCID: PMC4277910; DOI: 10.1016/j.metabol.2014.10.009;

Fufaa GD, Weil EJ, Nelson RG, Hanson RL, Bonventre JV, Sabbisetti V, Waikar SS, Mifflin TE, Zhang X, Xie D, Hsu CY, Feldman HI, Coresh J, Vasan RS, Kimmel PL, Liu KD. Association of urinary KIM-1, L-FABP, NAG and NGAL with incident end-stage renal disease and mortality in American Indians with type 2 diabetes mellitus. Diabetologia. 2015 Jan; 58(1):188-98.View Related Profiles.

Waikar, Sushrut
Ramachandran, Vasan

PMID: 25316431; PMCID: PMC4258130; DOI: 10.1007/s00125-014-3389-3;

Lorbeer R, Baumeister SE, Dörr M, Felix SB, Nauck M, Grotevendt A, Markus MR, von Sarnowski B, Völzke H, Vasan RS, Wallaschofski H, Lieb W. Angiopoietin-2, its soluble receptor Tie-2 and subclinical cardiovascular disease in a population-based sample. Heart. 2015 Feb; 101(3):178-84. PMID: 25286927; DOI: 10.1136/heartjnl-2014-306056;

Xanthakis V, Enserro DM, Murabito JM, Polak JF, Wollert KC, Januzzi JL, Wang TJ, Tofler G, Vasan RS. Ideal cardiovascular health: associations with biomarkers and subclinical disease and impact on incidence of cardiovascular disease in the Framingham Offspring Study. Circulation. 2014 Nov 4; 130(19):1676-83.View Related Profiles.

Murabito, Joanne
Polak, Joseph
Xanthakis, Vanessa
Ramachandran, Vasan

PMID: 25274000; DOI: 10.1161/CIRCULATIONAHA.114.009273;

Zakharov MN, Bhasin S, Travison TG, Xue R, Ulloor J, Vasan RS, Carter E, Wu F, Jasuja R. A multi-step, dynamic allosteric model of testosterone's binding to sex hormone binding globulin. Mol Cell Endocrinol. 2015 Jan 5; 399:190-200.View Related Profiles.

Ulloor, Jagadish
Zakharov, Mikhail
Bhasin, Shalender
Travison, Thomas
Ramachandran, Vasan

PMID: 25240469; DOI: 10.1016/j.mce.2014.09.001;

Lüneburg N, Lieb W, Zeller T, Chen MH, Maas R, Carter AM, Xanthakis V, Glazer NL, Schwedhelm E, Seshadri S, Ikram MA, Longstreth WT, Fornage M, König IR, Loley C, Ojeda FM, Schillert A, Wang TJ, Sticht H, Kittel A, König J, Benjamin EJ, Sullivan LM, Bernges I, Anderssohn M, Ziegler A, Gieger C, Illig T, Meisinger C, Wichmann HE, Wild PS, Schunkert H, Psaty BM, Wiggins KL, Heckbert SR, Smith N, Lackner K, Lunetta KL, Blankenberg S, Erdmann J, Munzel T, Grant PJ, Vasan RS, Böger RH. Genome-wide association study of L-arginine and dimethylarginines reveals novel metabolic pathway for symmetric dimethylarginine. Circ Cardiovasc Genet. 2014 Dec; 7(6):864-72.View Related Profiles.

Benjamin, Emelia
Lunetta, Kathryn
Sullivan, Lisa
Seshadri, Sudha
Xanthakis, Vanessa
Ramachandran, Vasan

PMID: 25245031; PMCID: PMC4797637; DOI: 10.1161/CIRCGENETICS.113.000264;

Gopal DM, Larson MG, Januzzi JL, Cheng S, Ghorbani A, Wollert KC, Kempf T, D'Agostino RB, Polak JF, Ramachandran VS, Wang TJ, Ho JE. Biomarkers of cardiovascular stress and subclinical atherosclerosis in the community. Clin Chem. 2014 Nov; 60(11):1402-8.View Related Profiles.

Gopal, Deepa
Ho, Jennifer
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Larson, Martin
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Ramachandran, Vasan

PMID: 25237063; PMCID: PMC4376479; DOI: 10.1373/clinchem.2014.227116;

Andersson C, Lyass A, Vasan RS, Massaro JM, D'Agostino RB, Robins SJ. Long-term risk of cardiovascular events across a spectrum of adverse major plasma lipid combinations in the Framingham Heart Study. Am Heart J. 2014 Dec; 168(6):878-83.e1.View Related Profiles.

Massaro, Joseph
D'Agostino, Ralph
Robins, Sander
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PMID: 25458651; DOI: 10.1016/j.ahj.2014.08.007;

Tsao CW, Pencina KM, Massaro JM, Benjamin EJ, Levy D, Vasan RS, Hoffmann U, O'Donnell CJ, Mitchell GF. Cross-sectional relations of arterial stiffness, pressure pulsatility, wave reflection, and arterial calcification. Arterioscler Thromb Vasc Biol. 2014 Nov; 34(11):2495-500.View Related Profiles.

O'Donnell, Christopher
Levy, Daniel
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PMID: 25169933; PMCID: PMC4199901; DOI: 10.1161/ATVBAHA.114.303916;

Lieb W, Gona P, Larson MG, Aragam J, Zile MR, Cheng S, Benjamin EJ, Vasan RS. The natural history of left ventricular geometry in the community: clinical correlates and prognostic significance of change in LV geometric pattern. JACC Cardiovasc Imaging. 2014 Sep; 7(9):870-8.View Related Profiles.

Benjamin, Emelia
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PMID: 25129518; PMCID: PMC4163746; DOI: 10.1016/j.jcmg.2014.05.008;

Andersson C, Vasan RS. Lower is not always better? Blood pressure treatment targets revisited. J Am Coll Cardiol. 2014 Aug 12; 64(6):598-600. PMID: 25104530; DOI: 10.1016/j.jacc.2014.04.066;

Ljungman PL, Wilker EH, Rice MB, Schwartz J, Gold DR, Koutrakis P, Vita JA, Mitchell GF, Vasan RS, Benjamin EJ, Mittleman MA, Hamburg NM. Short-term exposure to air pollution and digital vascular function. Am J Epidemiol. 2014 Sep 1; 180(5):482-9.View Related Profiles.

Benjamin, Emelia
Vita, Joseph
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PMID: 25100647; PMCID: PMC4143083; DOI: 10.1093/aje/kwu161;

Torjesen AA, Wang N, Larson MG, Hamburg NM, Vita JA, Levy D, Benjamin EJ, Vasan RS, Mitchell GF. Forward and backward wave morphology and central pressure augmentation in men and women in the Framingham Heart Study. Hypertension. 2014 Aug; 64(2):259-65.View Related Profiles.

Benjamin, Emelia
Vita, Joseph
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PMID: 24866142; PMCID: PMC4184952; DOI: 10.1161/HYPERTENSIONAHA.114.03371;

Rebholz CM, Grams ME, Coresh J, Selvin E, Inker LA, Levey AS, Kimmel PL, Vasan RS, Eckfeldt JH, Feldman HI, Hsu CY, Lutsey PL. Serum fibroblast growth factor-23 is associated with incident kidney disease. J Am Soc Nephrol. 2015 Jan; 26(1):192-200. PMID: 25060052; PMCID: PMC4279743; DOI: 10.1681/ASN.2014020218;

Sinner MF, Stepas KA, Moser CB, Krijthe BP, Aspelund T, Sotoodehnia N, Fontes JD, Janssens AC, Kronmal RA, Magnani JW, Witteman JC, Chamberlain AM, Lubitz SA, Schnabel RB, Vasan RS, Wang TJ, Agarwal SK, McManus DD, Franco OH, Yin X, Larson MG, Burke GL, Launer LJ, Hofman A, Levy D, Gottdiener JS, Kääb S, Couper D, Harris TB, Astor BC, Ballantyne CM, Hoogeveen RC, Arai AE, Soliman EZ, Ellinor PT, Stricker BH, Gudnason V, Heckbert SR, Pencina MJ, Benjamin EJ, Alonso A. B-type natriuretic peptide and C-reactive protein in the prediction of atrial fibrillation risk: the CHARGE-AF Consortium of community-based cohort studies. Europace. 2014 Oct; 16(10):1426-33.View Related Profiles.

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PMID: 25037055; PMCID: PMC4197895; DOI: 10.1093/europace/euu175;

Rutter MK, Sullivan LM, Fox CS, Wilson PW, Nathan DM, Vasan RS, D'Agostino RB, Meigs JB. Baseline levels, and changes over time in body mass index and fasting insulin, and their relationship to change in metabolic trait clustering. Metab Syndr Relat Disord. 2014 Sep; 12(7):372-80.View Related Profiles.

Sullivan, Lisa
D'Agostino, Ralph
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PMID: 25007010; PMCID: PMC4209491; DOI: 10.1089/met.2013.0148;

Andersson C, Vasan RS. Epidemiology of heart failure with preserved ejection fraction. Heart Fail Clin. 2014 Jul; 10(3):377-88. PMID: 24975902; PMCID: PMC4084609; DOI: 10.1016/j.hfc.2014.04.003;

Ganesh SK, Chasman DI, Larson MG, Guo X, Verwoert G, Bis JC, Gu X, Smith AV, Yang ML, Zhang Y, Ehret G, Rose LM, Hwang SJ, Papanicolau GJ, Sijbrands EJ, Rice K, Eiriksdottir G, Pihur V, Ridker PM, Vasan RS, Newton-Cheh C, Raffel LJ, Amin N, Rotter JI, Liu K, Launer LJ, Xu M, Caulfield M, Morrison AC, Johnson AD, Vaidya D, Dehghan A, Li G, Bouchard C, Harris TB, Zhang H, Boerwinkle E, Siscovick DS, Gao W, Uitterlinden AG, Rivadeneira F, Hofman A, Willer CJ, Franco OH, Huo Y, Witteman JC, Munroe PB, Gudnason V, Palmas W, van Duijn C, Fornage M, Levy D, Psaty BM, Chakravarti A. Effects of long-term averaging of quantitative blood pressure traits on the detection of genetic associations. Am J Hum Genet. 2014 Jul 3; 95(1):49-65.View Related Profiles.

Larson, Martin
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PMID: 24975945; PMCID: PMC4085637; DOI: 10.1016/j.ajhg.2014.06.002;

Simino J, Shi G, Bis JC, Chasman DI, Ehret GB, Gu X, Guo X, Hwang SJ, Sijbrands E, Smith AV, Verwoert GC, Bragg-Gresham JL, Cadby G, Chen P, Cheng CY, Corre T, de Boer RA, Goel A, Johnson T, Khor CC, Lluís-Ganella C, Luan J, Lyytikäinen LP, Nolte IM, Sim X, Sõber S, van der Most PJ, Verweij N, Zhao JH, Amin N, Boerwinkle E, Bouchard C, Dehghan A, Eiriksdottir G, Elosua R, Franco OH, Gieger C, Harris TB, Hercberg S, Hofman A, James AL, Johnson AD, Kähönen M, Khaw KT, Kutalik Z, Larson MG, Launer LJ, Li G, Liu J, Liu K, Morrison AC, Navis G, Ong RT, Papanicolau GJ, Penninx BW, Psaty BM, Raffel LJ, Raitakari OT, Rice K, Rivadeneira F, Rose LM, Sanna S, Scott RA, Siscovick DS, Stolk RP, Uitterlinden AG, Vaidya D, van der Klauw MM, Vasan RS, Vithana EN, Völker U, Völzke H, Watkins H, Young TL, Aung T, Bochud M, Farrall M, Hartman CA, Laan M, Lakatta EG, Lehtimäki T, Loos RJ, Lucas G, Meneton P, Palmer LJ, Rettig R, Snieder H, Tai ES, Teo YY, van der Harst P, Wareham NJ, Wijmenga C, Wong TY, Fornage M, Gudnason V, Levy D, Palmas W, Ridker PM, Rotter JI, van Duijn CM, Witteman JC, Chakravarti A, Rao DC. Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia. Am J Hum Genet. 2014 Jul 3; 95(1):24-38.View Related Profiles.

Larson, Martin
Ramachandran, Vasan

PMID: 24954895; PMCID: PMC4085636; DOI: 10.1016/j.ajhg.2014.05.010;

Evans DS, Cailotto F, Parimi N, Valdes AM, Castaño-Betancourt MC, Liu Y, Kaplan RC, Bidlingmaier M, Vasan RS, Teumer A, Tranah GJ, Nevitt MC, Cummings SR, Orwoll ES, Barrett-Connor E, Renner JB, Jordan JM, Doherty M, Doherty SA, Uitterlinden AG, van Meurs JB, Spector TD, Lories RJ, Lane NE. Genome-wide association and functional studies identify a role for IGFBP3 in hip osteoarthritis. Ann Rheum Dis. 2015 Oct; 74(10):1861-7. PMID: 24928840; PMCID: PMC4449305; DOI: 10.1136/annrheumdis-2013-205020;

Thankappan KR, Shah B, Mathur P, Sarma PS, Srinivas G, Mini GK, Daivadanam M, Soman B, Vasan RS. Authors' response. Indian J Med Res. 2014 Jun; 139(6):962. PMID: 25265651; PMCID: PMC4165019

Delling FN, Vasan RS. Epidemiology and pathophysiology of mitral valve prolapse: new insights into disease progression, genetics, and molecular basis. Circulation. 2014 May 27; 129(21):2158-70. PMID: 24867995; PMCID: PMC4052751; DOI: 10.1161/CIRCULATIONAHA.113.006702;

Zachariah JP, Graham DA, de Ferranti SD, Vasan RS, Newburger JW, Mitchell GF. Temporal trends in pulse pressure and mean arterial pressure during the rise of pediatric obesity in US children. J Am Heart Assoc. 2014 Jun; 3(3):e000725. PMID: 24811611; PMCID: PMC4309055; DOI: 10.1161/JAHA.113.000725;

Ho JE, Larson MG, Ghorbani A, Cheng S, Coglianese EE, Vasan RS, Wang TJ. Long-term cardiovascular risks associated with an elevated heart rate: the Framingham Heart Study. J Am Heart Assoc. 2014 Jun; 3(3):e000668.View Related Profiles.

Ho, Jennifer
Larson, Martin
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PMID: 24811610; PMCID: PMC4309047; DOI: 10.1161/JAHA.113.000668;

Paul L, Jacques PF, Aviv A, Vasan RS, D'Agostino RB, Levy D, Selhub J. High plasma folate is negatively associated with leukocyte telomere length in Framingham Offspring cohort. Eur J Nutr. 2015 Mar; 54(2):235-41.View Related Profiles.

D'Agostino, Ralph
Ramachandran, Vasan

PMID: 24793435; PMCID: PMC4218881; DOI: 10.1007/s00394-014-0704-1;

Amabile N, Cheng S, Renard JM, Larson MG, Ghorbani A, McCabe E, Griffin G, Guerin C, Ho JE, Shaw SY, Cohen KS, Vasan RS, Tedgui A, Boulanger CM, Wang TJ. Association of circulating endothelial microparticles with cardiometabolic risk factors in the Framingham Heart Study. Eur Heart J. 2014 Nov 7; 35(42):2972-9.View Related Profiles.

Ho, Jennifer
Larson, Martin
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PMID: 24742886; PMCID: PMC4223610; DOI: 10.1093/eurheartj/ehu153;

Xanthakis V, Sullivan LM, Vasan RS, Benjamin EJ, Massaro JM, D'Agostino RB, Pencina MJ. Assessing the incremental predictive performance of novel biomarkers over standard predictors. Stat Med. 2014 Jul 10; 33(15):2577-84.View Related Profiles.

Benjamin, Emelia
Massaro, Joseph
Sullivan, Lisa
Pencina, Michael
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Xanthakis, Vanessa
Ramachandran, Vasan

PMID: 24719270; PMCID: PMC4047140; DOI: 10.1002/sim.6165;

Westwood AJ, Beiser A, Decarli C, Harris TB, Chen TC, He XM, Roubenoff R, Pikula A, Au R, Braverman LE, Wolf PA, Vasan RS, Seshadri S. Insulin-like growth factor-1 and risk of Alzheimer dementia and brain atrophy. Neurology. 2014 May 6; 82(18):1613-9.View Related Profiles.

Pikula, Aleksandra
Beiser, Alexa
Braverman, Lewis
Wolf, Philip
Au, Rhoda
Seshadri, Sudha
Chen, Tai
Ramachandran, Vasan

PMID: 24706014; PMCID: PMC4013812; DOI: 10.1212/WNL.0000000000000382;

Wilker EH, Ljungman PL, Rice MB, Kloog I, Schwartz J, Gold DR, Koutrakis P, Vita JA, Mitchell GF, Vasan RS, Benjamin EJ, Hamburg NM, Mittleman MA. Relation of long-term exposure to air pollution to brachial artery flow-mediated dilation and reactive hyperemia. Am J Cardiol. 2014 Jun 15; 113(12):2057-63.View Related Profiles.

Benjamin, Emelia
Vita, Joseph
Hamburg, Naomi
Ramachandran, Vasan

PMID: 24793676; PMCID: PMC4066389; DOI: 10.1016/j.amjcard.2014.03.048;

Ellis J, Lange EM, Li J, Dupuis J, Baumert J, Walston JD, Keating BJ, Durda P, Fox ER, Palmer CD, Meng YA, Young T, Farlow DN, Schnabel RB, Marzi CS, Larkin E, Martin LW, Bis JC, Auer P, Ramachandran VS, Gabriel SB, Willis MS, Pankow JS, Papanicolaou GJ, Rotter JI, Ballantyne CM, Gross MD, Lettre G, Wilson JG, Peters U, Koenig W, Tracy RP, Redline S, Reiner AP, Benjamin EJ, Lange LA. Large multiethnic Candidate Gene Study for C-reactive protein levels: identification of a novel association at CD36 in African Americans. Hum Genet. 2014 Aug; 133(8):985-95.View Related Profiles.

Benjamin, Emelia
Dupuis, Josee
Ramachandran, Vasan

PMID: 24643644; PMCID: PMC4104766; DOI: 10.1007/s00439-014-1439-z;

Magnani JW, Moser CB, Murabito JM, Sullivan LM, Wang N, Ellinor PT, Vasan RS, Benjamin EJ, Coviello AD. Association of sex hormones, aging, and atrial fibrillation in men: the Framingham Heart Study. Circ Arrhythm Electrophysiol. 2014 Apr; 7(2):307-12.View Related Profiles.

Coviello, Andrea
Benjamin, Emelia
Magnani, Jared
Murabito, Joanne
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PMID: 24610804; PMCID: PMC4035016; DOI: 10.1161/CIRCEP.113.001322;

Andersson C, Vasan RS. Is there a role for coronary artery calcium scoring for management of asymptomatic patients at risk for coronary artery disease?: Clinical risk scores are sufficient to define primary prevention treatment strategies among asymptomatic patients. Circ Cardiovasc Imaging. 2014 Mar; 7(2):390-7; discussion 397. PMID: 24642921; PMCID: PMC4154564; DOI: 10.1161/CIRCIMAGING.113.000470;

Ho JE, Yin X, Levy D, Vasan RS, Magnani JW, Ellinor PT, McManus DD, Lubitz SA, Larson MG, Benjamin EJ. Galectin 3 and incident atrial fibrillation in the community. Am Heart J. 2014 May; 167(5):729-34.e1.View Related Profiles.

Benjamin, Emelia
Magnani, Jared
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PMID: 24766984; PMCID: PMC4007212; DOI: 10.1016/j.ahj.2014.02.009;

Cheng S, Enserro D, Xanthakis V, Sullivan LM, Murabito JM, Benjamin EJ, Polak JF, O'Donnell CJ, Wolf PA, O'Connor GT, Keaney JF, Vasan RS. Association of exhaled carbon monoxide with subclinical cardiovascular disease and their conjoint impact on the incidence of cardiovascular outcomes. Eur Heart J. 2014 Nov 7; 35(42):2980-7.View Related Profiles.

O'Donnell, Christopher
Benjamin, Emelia
O'Connor, George
Murabito, Joanne
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Sullivan, Lisa
Wolf, Philip
Xanthakis, Vanessa
Ramachandran, Vasan

PMID: 24574370; PMCID: PMC4271053; DOI: 10.1093/eurheartj/ehu052;

Tragante V, Barnes MR, Ganesh SK, Lanktree MB, Guo W, Franceschini N, Smith EN, Johnson T, Holmes MV, Padmanabhan S, Karczewski KJ, Almoguera B, Barnard J, Baumert J, Chang YP, Elbers CC, Farrall M, Fischer ME, Gaunt TR, Gho JM, Gieger C, Goel A, Gong Y, Isaacs A, Kleber ME, Mateo Leach I, McDonough CW, Meijs MF, Melander O, Nelson CP, Nolte IM, Pankratz N, Price TS, Shaffer J, Shah S, Tomaszewski M, van der Most PJ, Van Iperen EP, Vonk JM, Witkowska K, Wong CO, Zhang L, Beitelshees AL, Berenson GS, Bhatt DL, Brown M, Burt A, Cooper-DeHoff RM, Connell JM, Cruickshanks KJ, Curtis SP, Davey-Smith G, Delles C, Gansevoort RT, Guo X, Haiqing S, Hastie CE, Hofker MH, Hovingh GK, Kim DS, Kirkland SA, Klein BE, Klein R, Li YR, Maiwald S, Newton-Cheh C, O'Brien ET, Onland-Moret NC, Palmas W, Parsa A, Penninx BW, Pettinger M, Vasan RS, Ranchalis JE, M Ridker P, Rose LM, Sever P, Shimbo D, Steele L, Stolk RP, Thorand B, Trip MD, van Duijn CM, Verschuren WM, Wijmenga C, Wyatt S, Young JH, Zwinderman AH, Bezzina CR, Boerwinkle E, Casas JP, Caulfield MJ, Chakravarti A, Chasman DI, Davidson KW, Doevendans PA, Dominiczak AF, FitzGerald GA, Gums JG, Fornage M, Hakonarson H, Halder I, Hillege HL, Illig T, Jarvik GP, Johnson JA, Kastelein JJ, Koenig W, Kumari M, März W, Murray SS, O'Connell JR, Oldehinkel AJ, Pankow JS, Rader DJ, Redline S, Reilly MP, Schadt EE, Kottke-Marchant K, Snieder H, Snyder M, Stanton AV, Tobin MD, Uitterlinden AG, van der Harst P, van der Schouw YT, Samani NJ, Watkins H, Johnson AD, Reiner AP, Zhu X, de Bakker PI, Levy D, Asselbergs FW, Munroe PB, Keating BJ. Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci. Am J Hum Genet. 2014 Mar 6; 94(3):349-60. PMID: 24560520; PMCID: PMC3951943; DOI: 10.1016/j.ajhg.2013.12.016;

Fox CS, Pencina MJ, Heard-Costa NL, Shrader P, Jaquish C, O'Donnell CJ, Vasan RS, Cupples LA, D'Agostino RB. Trends in the association of parental history of obesity over 60 years. Obesity (Silver Spring). 2014 Mar; 22(3):919-24.View Related Profiles.

O'Donnell, Christopher
Cupples, L
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PMID: 23836774; PMCID: PMC3887126; DOI: 10.1002/oby.20564;

MacRae CA, Vasan RS. Clinically relevant functional annotation of genotype. Circ Cardiovasc Genet. 2014 Feb; 7(1):2-3. PMID: 24550428; PMCID: PMC4188549; DOI: 10.1161/CIRCGENETICS.114.000506;

Roberts LD, Boström P, O'Sullivan JF, Schinzel RT, Lewis GD, Dejam A, Lee YK, Palma MJ, Calhoun S, Georgiadi A, Chen MH, Ramachandran VS, Larson MG, Bouchard C, Rankinen T, Souza AL, Clish CB, Wang TJ, Estall JL, Soukas AA, Cowan CA, Spiegelman BM, Gerszten RE. ß-Aminoisobutyric acid induces browning of white fat and hepatic ß-oxidation and is inversely correlated with cardiometabolic risk factors. Cell Metab. 2014 Jan 7; 19(1):96-108.View Related Profiles.

Larson, Martin
Ramachandran, Vasan

PMID: 24411942; PMCID: PMC4017355; DOI: 10.1016/j.cmet.2013.12.003;

Weinstein G, Beiser AS, Choi SH, Preis SR, Chen TC, Vorgas D, Au R, Pikula A, Wolf PA, DeStefano AL, Vasan RS, Seshadri S. Serum brain-derived neurotrophic factor and the risk for dementia: the Framingham Heart Study. JAMA Neurol. 2014 Jan; 71(1):55-61.View Related Profiles.

Pikula, Aleksandra
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Au, Rhoda
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Choi, Seung Hoan
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Chen, Tai
Ramachandran, Vasan

PMID: 24276217; PMCID: PMC4056186; DOI: 10.1001/jamaneurol.2013.4781;

Ganesh SK, Arnett DK, Assimes TL, Assimes TL, Basson CT, Chakravarti A, Ellinor PT, Engler MB, Goldmuntz E, Herrington DM, Hershberger RE, Hong Y, Johnson JA, Kittner SJ, McDermott DA, Meschia JF, Mestroni L, O'Donnell CJ, Psaty BM, Vasan RS, Ruel M, Shen WK, Terzic A, Waldman SA. Genetics and genomics for the prevention and treatment of cardiovascular disease: update: a scientific statement from the American Heart Association. Circulation. 2013 Dec 24; 128(25):2813-51.View Related Profiles.

O'Donnell, Christopher
Ramachandran, Vasan

PMID: 24297835; DOI: 10.1161/01.cir.0000437913.98912.1d;

Tsao CW, Vasan RS. Imaging of arterial inflammation: keeping our cool on a hot topic. JACC Cardiovasc Imaging. 2013 Dec; 6(12):1260-2. PMID: 24332279; DOI: 10.1016/j.jcmg.2013.09.010;

Ben-Shlomo Y, Spears M, Boustred C, May M, Anderson SG, Benjamin EJ, Boutouyrie P, Cameron J, Chen CH, Cruickshank JK, Hwang SJ, Lakatta EG, Laurent S, Maldonado J, Mitchell GF, Najjar SS, Newman AB, Ohishi M, Pannier B, Pereira T, Vasan RS, Shokawa T, Sutton-Tyrell K, Verbeke F, Wang KL, Webb DJ, Willum Hansen T, Zoungas S, McEniery CM, Cockcroft JR, Wilkinson IB. Aortic pulse wave velocity improves cardiovascular event prediction: an individual participant meta-analysis of prospective observational data from 17,635 subjects. J Am Coll Cardiol. 2014 Feb 25; 63(7):636-46.View Related Profiles.

Benjamin, Emelia
Hwang, Shih-Jen
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PMID: 24239664; PMCID: PMC4401072; DOI: 10.1016/j.jacc.2013.09.063;

Xanthakis V, Larson MG, Wollert KC, Aragam J, Cheng S, Ho J, Coglianese E, Levy D, Colucci WS, Michael Felker G, Benjamin EJ, Januzzi JL, Wang TJ, Vasan RS. Association of novel biomarkers of cardiovascular stress with left ventricular hypertrophy and dysfunction: implications for screening. J Am Heart Assoc. 2013; 2(6):e000399.View Related Profiles.

Benjamin, Emelia
Aragam, Jayashri
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Larson, Martin
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Colucci, Wilson

PMID: 24200688; PMCID: PMC3886765; DOI: 10.1161/JAHA.113.000399;

Evans DM, Brion MJ, Paternoster L, Kemp JP, McMahon G, Munafò M, Whitfield JB, Medland SE, Montgomery GW, Timpson NJ, St Pourcain B, Lawlor DA, Martin NG, Dehghan A, Hirschhorn J, Smith GD. Mining the human phenome using allelic scores that index biological intermediates. PLoS Genet. 2013 Oct; 9(10):e1003919.View Related Profiles.

Preis, Sarah
Ramachandran, Vasan

PMID: 24204319; PMCID: PMC3814299; DOI: 10.1371/journal.pgen.1003919;

Wang T, Zhou B, Guo T, Bidlingmaier M, Wallaschofski H, Teumer A, Vasan RS, Kaplan RC. A robust method for genome-wide association meta-analysis with the application to circulating insulin-like growth factor I concentrations. Genet Epidemiol. 2014 Feb; 38(2):162-71. PMID: 24446417; PMCID: PMC4049273; DOI: 10.1002/gepi.21766;

Delling FN, Gona P, Larson MG, Lehman B, Manning WJ, Levine RA, Benjamin EJ, Vasan RS. Mild expression of mitral valve prolapse in the Framingham offspring: expanding the phenotypic spectrum. J Am Soc Echocardiogr. 2014 Jan; 27(1):17-23.View Related Profiles.

Benjamin, Emelia
Larson, Martin
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PMID: 24206636; PMCID: PMC4239996; DOI: 10.1016/j.echo.2013.09.015;

Rienstra M, Yin X, Larson MG, Fontes JD, Magnani JW, McManus DD, McCabe EL, Coglianese EE, Amponsah M, Ho JE, Januzzi JL, Wollert KC, Fradley MG, Vasan RS, Ellinor PT, Wang TJ, Benjamin EJ. Relation between soluble ST2, growth differentiation factor-15, and high-sensitivity troponin I and incident atrial fibrillation. Am Heart J. 2014 Jan; 167(1):109-115.e2.View Related Profiles.

Benjamin, Emelia
Magnani, Jared
Ho, Jennifer
Larson, Martin
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PMID: 24332149; PMCID: PMC3884900; DOI: 10.1016/j.ahj.2013.10.003;

Velagaleti RS, Gona P, Pencina MJ, Aragam J, Wang TJ, Levy D, D'Agostino RB, Lee DS, Kannel WB, Benjamin EJ, Vasan RS. Left ventricular hypertrophy patterns and incidence of heart failure with preserved versus reduced ejection fraction. Am J Cardiol. 2014 Jan 1; 113(1):117-22.View Related Profiles.

Benjamin, Emelia
Aragam, Jayashri
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Ramachandran, Vasan

PMID: 24210333; PMCID: PMC3881171; DOI: 10.1016/j.amjcard.2013.09.028;

Thorgeirsson TE, Gudbjartsson DF, Sulem P, Besenbacher S, Styrkarsdottir U, Thorleifsson G, Walters GB, Furberg H, Sullivan PF, Marchini J, McCarthy MI, Steinthorsdottir V, Thorsteinsdottir U, Stefansson K. A common biological basis of obesity and nicotine addiction. Transl Psychiatry. 2013; 3:e308. PMID: 24084939; PMCID: PMC3818010; DOI: 10.1038/tp.2013.81;

Mahmood SS, Levy D, Vasan RS, Wang TJ. The Framingham Heart Study and the epidemiology of cardiovascular disease: a historical perspective. Lancet. 2014 Mar 15; 383(9921):999-1008. PMID: 24084292; PMCID: PMC4159698; DOI: 10.1016/S0140-6736(13)61752-3;

Armah KA, Chang CC, Baker JV, Ramachandran VS, Budoff MJ, Crane HM, Gibert CL, Goetz MB, Leaf DA, McGinnis KA, Oursler KK, Rimland D, Rodriguez-Barradas MC, Sico JJ, Warner AL, Hsue PY, Kuller LH, Justice AC, Freiberg MS. Prehypertension, hypertension, and the risk of acute myocardial infarction in HIV-infected and -uninfected veterans. Clin Infect Dis. 2014 Jan; 58(1):121-9.View Related Profiles.

So-Armah, Kaku
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PMID: 24065316; PMCID: PMC3864500; DOI: 10.1093/cid/cit652;

Haugen IK, Ramachandran VS, Misra D, Neogi T, Niu J, Yang T, Zhang Y, Felson DT. Hand osteoarthritis in relation to mortality and incidence of cardiovascular disease: data from the Framingham heart study. Ann Rheum Dis. 2015 Jan; 74(1):74-81.View Related Profiles.

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PMID: 24047870; PMCID: PMC3959628; DOI: 10.1136/annrheumdis-2013-203789;

Kaess BM, Gona P, Larson MG, Cheng S, Aragam J, Kenchaiah S, Benjamin EJ, Vasan RS. Secular trends in echocardiographic left ventricular mass in the community: the Framingham Heart Study. Heart. 2013 Nov; 99(22):1693-8.View Related Profiles.

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PMID: 24041649; PMCID: PMC4139052; DOI: 10.1136/heartjnl-2013-304600;

Wang TJ, Ngo D, Psychogios N, Dejam A, Larson MG, Vasan RS, Ghorbani A, O'Sullivan J, Cheng S, Rhee EP, Sinha S, McCabe E, Fox CS, O'Donnell CJ, Ho JE, Florez JC, Magnusson M, Pierce KA, Souza AL, Yu Y, Carter C, Light PE, Melander O, Clish CB, Gerszten RE. 2-Aminoadipic acid is a biomarker for diabetes risk. J Clin Invest. 2013 Oct 1; 123(10):4309-17.View Related Profiles.

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PMID: 24091325; PMCID: PMC3784523; DOI: 10.1172/JCI64801;

Lieb W, Vasan RS. Genetics of coronary artery disease. Circulation. 2013 Sep 3; 128(10):1131-8. PMID: 24002717; PMCID: PMC3881185; DOI: 10.1161/CIRCULATIONAHA.113.005350;

Ho JE, Chen WY, Chen MH, Larson MG, McCabe EL, Cheng S, Ghorbani A, Coglianese E, Emilsson V, Johnson AD, Walter S, Franceschini N, O'Donnell CJ, Dehghan A, Lu C, Levy D, Newton-Cheh C, Lin H, Felix JF, Schreiter ER, Vasan RS, Januzzi JL, Lee RT, Wang TJ, Assimes TL, Deloukas P, Erdmann J, Holm H, Kathiresan S, König IR, McPherson R, Reilly MP, Roberts R, Samani NJ, Schunkert H, Stewart AF. Common genetic variation at the IL1RL1 locus regulates IL-33/ST2 signaling. J Clin Invest. 2013 Oct 1; 123(10):4208-18.View Related Profiles.

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PMID: 23999434; PMCID: PMC3784527; DOI: 10.1172/JCI67119;

O'Seaghdha CM, Hwang SJ, Larson MG, Meigs JB, Vasan RS, Fox CS. Analysis of a urinary biomarker panel for incident kidney disease and clinical outcomes. J Am Soc Nephrol. 2013 Nov; 24(11):1880-8.View Related Profiles.

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PMID: 23990678; PMCID: PMC3810081; DOI: 10.1681/ASN.2013010019;

Cheng S, Larson MG, McCabe EL, Osypiuk E, Lehman BT, Stanchev P, Aragam J, Benjamin EJ, Solomon SD, Vasan RS. Reproducibility of speckle-tracking-based strain measures of left ventricular function in a community-based study. J Am Soc Echocardiogr. 2013 Nov; 26(11):1258-1266.e2.View Related Profiles.

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PMID: 23953701; PMCID: PMC3812381; DOI: 10.1016/j.echo.2013.07.002;

Tsao CW, Seshadri S, Beiser AS, Westwood AJ, Decarli C, Au R, Himali JJ, Hamburg NM, Vita JA, Levy D, Larson MG, Benjamin EJ, Wolf PA, Vasan RS, Mitchell GF. Relations of arterial stiffness and endothelial function to brain aging in the community. Neurology. 2013 Sep 10; 81(11):984-91.View Related Profiles.

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PMID: 23935179; PMCID: PMC3888200; DOI: 10.1212/WNL.0b013e3182a43e1c;

Pikula A, Beiser AS, Chen TC, Preis SR, Vorgias D, DeCarli C, Au R, Kelly-Hayes M, Kase CS, Wolf PA, Vasan RS, Seshadri S. Serum brain-derived neurotrophic factor and vascular endothelial growth factor levels are associated with risk of stroke and vascular brain injury: Framingham Study. Stroke. 2013 Oct; 44(10):2768-75.View Related Profiles.

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PMID: 23929745; PMCID: PMC3873715; DOI: 10.1161/STROKEAHA.113.001447;

Cheng S, Larson MG, McCabe EL, Osypiuk E, Lehman BT, Stanchev P, Aragam J, Benjamin EJ, Solomon SD, Vasan RS. Age- and sex-based reference limits and clinical correlates of myocardial strain and synchrony: the Framingham Heart Study. Circ Cardiovasc Imaging. 2013 Sep; 6(5):692-9.View Related Profiles.

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PMID: 23917618; PMCID: PMC3856433; DOI: 10.1161/CIRCIMAGING.112.000627;

Lorbeer R, Baumeister SE, Dörr M, Nauck M, Grotevendt A, Völzke H, Vasan RS, Wallaschofski H, Lieb W. Circulating angiopoietin-2, its soluble receptor Tie-2, and mortality in the general population. Eur J Heart Fail. 2013 Dec; 15(12):1327-34. PMID: 23901057; DOI: 10.1093/eurjhf/hft117;

Singh GM, Danaei G, Farzadfar F, Stevens GA, Woodward M, Wormser D, Kaptoge S, Whitlock G, Qiao Q, Lewington S, Di Angelantonio E, Vander Hoorn S, Lawes CM, Ali MK, Mozaffarian D, Ezzati M. The age-specific quantitative effects of metabolic risk factors on cardiovascular diseases and diabetes: a pooled analysis. PLoS One. 2013; 8(7):e65174. PMID: 23935815; PMCID: PMC3728292; DOI: 10.1371/journal.pone.0065174;

Ho JE, Hwang SJ, Wollert KC, Larson MG, Cheng S, Kempf T, Vasan RS, Januzzi JL, Wang TJ, Fox CS. Biomarkers of cardiovascular stress and incident chronic kidney disease. Clin Chem. 2013 Nov; 59(11):1613-20.View Related Profiles.

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PMID: 23873716; PMCID: PMC3972213; DOI: 10.1373/clinchem.2013.205716;

Yaghootkar H, Lamina C, Scott RA, Dastani Z, Hivert MF, Warren LL, Stancáková A, Buxbaum SG, Lyytikäinen LP, Henneman P, Wu Y, Cheung CY, Pankow JS, Jackson AU, Gustafsson S, Zhao JH, Ballantyne CM, Xie W, Bergman RN, Boehnke M, el Bouazzaoui F, Collins FS, Dunn SH, Dupuis J, Forouhi NG, Gillson C, Hattersley AT, Hong J, Kähönen M, Kuusisto J, Kedenko L, Kronenberg F, Doria A, Assimes TL, Ferrannini E, Hansen T, Hao K, Häring H, Knowles JW, Lindgren CM, Nolan JJ, Paananen J, Pedersen O, Quertermous T, Smith U, Lehtimäki T, Liu CT, Loos RJ, McCarthy MI, Morris AD, Vasan RS, Spector TD, Teslovich TM, Tuomilehto J, van Dijk KW, Viikari JS, Zhu N, Langenberg C, Ingelsson E, Semple RK, Sinaiko AR, Palmer CN, Walker M, Lam KS, Paulweber B, Mohlke KL, van Duijn C, Raitakari OT, Bidulescu A, Wareham NJ, Laakso M, Waterworth DM, Lawlor DA, Meigs JB, Richards JB, Frayling TM. Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes. Diabetes. 2013 Oct; 62(10):3589-98.View Related Profiles.

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PMID: 23835345; PMCID: PMC3781444; DOI: 10.2337/db13-0128;

Rhee EP, Ho JE, Chen MH, Shen D, Cheng S, Larson MG, Ghorbani A, Shi X, Helenius IT, O'Donnell CJ, Souza AL, Deik A, Pierce KA, Bullock K, Walford GA, Vasan RS, Florez JC, Clish C, Yeh JR, Wang TJ, Gerszten RE. A genome-wide association study of the human metabolome in a community-based cohort. Cell Metab. 2013 Jul 2; 18(1):130-43.View Related Profiles.

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PMID: 23823483; PMCID: PMC3973158; DOI: 10.1016/j.cmet.2013.06.013;

Ho JE, Larson MG, Ghorbani A, Cheng S, Vasan RS, Wang TJ, Januzzi JL. Soluble ST2 predicts elevated SBP in the community. J Hypertens. 2013 Jul; 31(7):1431-6; discussion 1436.View Related Profiles.

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PMID: 23615326; PMCID: PMC3986262; DOI: 10.1097/HJH.0b013e3283611bdf;

Xanthakis V, Sullivan LM, Vasan RS. Multilevel modeling versus cross-sectional analysis for assessing the longitudinal tracking of cardiovascular risk factors over time. Stat Med. 2013 Dec 10; 32(28):5028-38.View Related Profiles.

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PMID: 23784950; PMCID: PMC4068405; DOI: 10.1002/sim.5880;

O'Seaghdha CM, Hwang SJ, Ho JE, Vasan RS, Levy D, Fox CS. Elevated galectin-3 precedes the development of CKD. J Am Soc Nephrol. 2013 Sep; 24(9):1470-7.View Related Profiles.

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PMID: 23766533; PMCID: PMC3752944; DOI: 10.1681/ASN.2012090909;

Adlin EV, Braitman LE, Vasan RS. Bimodal aldosterone distribution in low-renin hypertension. Am J Hypertens. 2013 Sep; 26(9):1076-85. PMID: 23757402; PMCID: PMC3741228; DOI: 10.1093/ajh/hpt091;

Musani SK, Vasan RS, Bidulescu A, Liu J, Xanthakis V, Sims M, Gawalapu RK, Samdarshi TE, Steffes M, Taylor HA, Fox ER. Aldosterone, C-reactive protein, and plasma B-type natriuretic peptide are associated with the development of metabolic syndrome and longitudinal changes in metabolic syndrome components: findings from the Jackson Heart Study. Diabetes Care. 2013 Oct; 36(10):3084-92.View Related Profiles.

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PMID: 23757435; PMCID: PMC3781556; DOI: 10.2337/dc12-2562;

Britton KA, Wang N, Palmisano J, Corsini E, Schlett CL, Hoffmann U, Larson MG, Vasan RS, Vita JA, Mitchell GF, Benjamin EJ, Hamburg NM, Fox CS. Thoracic periaortic and visceral adipose tissue and their cross-sectional associations with measures of vascular function. Obesity (Silver Spring). 2013 Jul; 21(7):1496-503.View Related Profiles.

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PMID: 23754461; PMCID: PMC3742564; DOI: 10.1002/oby.20166;

Tsao CW, Vasan RS. Diagnosis: Biomarkers of cardiovascular outcomes--bonanza or bias? Nat Rev Endocrinol. 2013 Jul; 9(7):381-2. PMID: 23689815; DOI: 10.1038/nrendo.2013.99;

Jasuja GK, Travison TG, Davda M, Rose AJ, Zhang A, Kushnir MM, Rockwood AL, Meikle W, Coviello AD, D'Agostino R, Vasan RS, Bhasin S. Circulating estrone levels are associated prospectively with diabetes risk in men of the Framingham Heart Study. Diabetes Care. 2013 Sep; 36(9):2591-6.View Related Profiles.

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PMID: 23690532; PMCID: PMC3747918; DOI: 10.2337/dc12-2477;

Rhee EP, Clish CB, Ghorbani A, Larson MG, Elmariah S, McCabe E, Yang Q, Cheng S, Pierce K, Deik A, Souza AL, Farrell L, Domos C, Yeh RW, Palacios I, Rosenfield K, Vasan RS, Florez JC, Wang TJ, Fox CS, Gerszten RE. A combined epidemiologic and metabolomic approach improves CKD prediction. J Am Soc Nephrol. 2013 Jul; 24(8):1330-8.View Related Profiles.

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PMID: 23687356; PMCID: PMC3736702; DOI: 10.1681/ASN.2012101006;

Schnabel RB, Yin X, Larson MG, Yamamoto JF, Fontes JD, Kathiresan S, Rong J, Levy D, Keaney JF, Wang TJ, Murabito JM, Vasan RS, Benjamin EJ. Multiple inflammatory biomarkers in relation to cardiovascular events and mortality in the community. Arterioscler Thromb Vasc Biol. 2013 Jul; 33(7):1728-33.View Related Profiles.

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PMID: 23640499; PMCID: PMC3753537; DOI: 10.1161/ATVBAHA.112.301174;

Chami HA, Fontes JD, Vasan RS, Keaney JF, O'Connor GT, Larson MG, Benjamin EJ, Gottlieb DJ. Vascular inflammation and sleep disordered breathing in a community-based cohort. Sleep. 2013 May; 36(5):763-768C.View Related Profiles.

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PMID: 23633759; PMCID: PMC3622647; DOI: 10.5665/sleep.2644;

Ge Y, Cheng S, Larson MG, Ghorbani A, Martin RP, Klein RJ, O'Donnell CJ, Vasan RS, Shaw SY, Wang TJ, Cohen KS. Circulating CD31+ leukocyte frequency is associated with cardiovascular risk factors. Atherosclerosis. 2013 Jul; 229(1):228-33.View Related Profiles.

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PMID: 23701996; PMCID: PMC3984590; DOI: 10.1016/j.atherosclerosis.2013.04.017;

Schnabel RB, Rienstra M, Sullivan LM, Sun JX, Moser CB, Levy D, Pencina MJ, Fontes JD, Magnani JW, McManus DD, Lubitz SA, Tadros TM, Wang TJ, Ellinor PT, Vasan RS, Benjamin EJ. Risk assessment for incident heart failure in individuals with atrial fibrillation. Eur J Heart Fail. 2013 Aug; 15(8):843-9.View Related Profiles.

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PMID: 23594831; PMCID: PMC3858114; DOI: 10.1093/eurjhf/hft041;

Haring R, Teng Z, Xanthakis V, Coviello A, Sullivan L, Bhasin S, Murabito JM, Wallaschofski H, Vasan RS. Association of sex steroids, gonadotrophins, and their trajectories with clinical cardiovascular disease and all-cause mortality in elderly men from the Framingham Heart Study. Clin Endocrinol (Oxf). 2013 Apr; 78(4):629-34.View Related Profiles.

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PMID: 22901104; PMCID: PMC4161203 ; DOI: 10.1111/cen.12013;

Xanthakis V, Vasan RS. Aldosterone and the risk of hypertension. Curr Hypertens Rep. 2013 Apr; 15(2):102-7.View Related Profiles.

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PMID: 23378101; PMCID: PMC3619380; DOI: 10.1007/s11906-013-0330-y;

Lieb W, Jansen H, Loley C, Pencina MJ, Nelson CP, Newton-Cheh C, Kathiresan S, Reilly MP, Assimes TL, Boerwinkle E, Hall AS, Hengstenberg C, Laaksonen R, McPherson R, Thorsteinsdottir U, Ziegler A, Peters A, Thompson JR, König IR, Erdmann J, Samani NJ, Vasan RS, Schunkert H, Assimes TL, Deloukas P, Erdmann J, Holm H, Kathiresan S, König IR, McPherson R, Reilly MP, Roberts R, Samani NJ, Schunkert H, Stewart AF. Genetic predisposition to higher blood pressure increases coronary artery disease risk. Hypertension. 2013 May; 61(5):995-1001.View Related Profiles.

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PMID: 23478099; PMCID: PMC3855241; DOI: 10.1161/HYPERTENSIONAHA.111.00275;

Kraigher-Krainer E, Lyass A, Massaro JM, Lee DS, Ho JE, Levy D, Kannel WB, Vasan RS. Association of physical activity and heart failure with preserved vs. reduced ejection fraction in the elderly: the Framingham Heart Study. Eur J Heart Fail. 2013 Jul; 15(7):742-6.View Related Profiles.

Ho, Jennifer
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PMID: 23435761; PMCID: PMC3857918; DOI: 10.1093/eurjhf/hft025;

Robins SJ, Lyass A, Brocia RW, Massaro JM, Vasan RS. Plasma lipid transfer proteins and cardiovascular disease. The Framingham Heart Study. Atherosclerosis. 2013 May; 228(1):230-6.View Related Profiles.

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PMID: 23477743; PMCID: PMC3692011; DOI: 10.1016/j.atherosclerosis.2013.01.046;

Fontes JD, Yamamoto JF, Larson MG, Wang N, Dallmeier D, Rienstra M, Schnabel RB, Vasan RS, Keaney JF, Benjamin EJ. Clinical correlates of change in inflammatory biomarkers: The Framingham Heart Study. Atherosclerosis. 2013 May; 228(1):217-23.View Related Profiles.

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PMID: 23489346; PMCID: PMC3650714; DOI: 10.1016/j.atherosclerosis.2013.01.019;

Ho JE, Larson MG, Vasan RS, Ghorbani A, Cheng S, Rhee EP, Florez JC, Clish CB, Gerszten RE, Wang TJ. Metabolite profiles during oral glucose challenge. Diabetes. 2013 Aug; 62(8):2689-98.View Related Profiles.

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PMID: 23382451; PMCID: PMC3717862; DOI: 10.2337/db12-0754;

Lam CS, Gona P, Larson MG, Aragam J, Lee DS, Mitchell GF, Levy D, Cheng S, Benjamin EJ, Vasan RS. Aortic root remodeling and risk of heart failure in the Framingham Heart study. JACC Heart Fail. 2013 Feb; 1(1):79-83.View Related Profiles.

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PMID: 23998002; PMCID: PMC3755769; DOI: 10.1016/j.jchf.2012.10.003;

Jacques PF, Lyass A, Massaro JM, Vasan RS, D'Agostino RB. Relationship of lycopene intake and consumption of tomato products to incident CVD. Br J Nutr. 2013 Aug 28; 110(3):545-51.View Related Profiles.

Massaro, Joseph
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PMID: 23317928; PMCID: PMC3710301; DOI: 10.1017/S0007114512005417;

Ganesh SK, Tragante V, Guo W, Guo Y, Lanktree MB, Smith EN, Johnson T, Castillo BA, Barnard J, Baumert J, Chang YP, Elbers CC, Farrall M, Fischer ME, Franceschini N, Gaunt TR, Gho JM, Gieger C, Gong Y, Isaacs A, Kleber ME, Mateo Leach I, McDonough CW, Meijs MF, Mellander O, Molony CM, Nolte IM, Padmanabhan S, Price TS, Rajagopalan R, Shaffer J, Shah S, Shen H, Soranzo N, van der Most PJ, Van Iperen EP, Van Setten J, Van Setten JA, Vonk JM, Zhang L, Beitelshees AL, Berenson GS, Bhatt DL, Boer JM, Boerwinkle E, Burkley B, Burt A, Chakravarti A, Chen W, Cooper-Dehoff RM, Curtis SP, Dreisbach A, Duggan D, Ehret GB, Fabsitz RR, Fornage M, Fox E, Furlong CE, Gansevoort RT, Hofker MH, Hovingh GK, Kirkland SA, Kottke-Marchant K, Kutlar A, Lacroix AZ, Langaee TY, Li YR, Lin H, Liu K, Maiwald S, Malik R, Murugesan G, Newton-Cheh C, O'Connell JR, Onland-Moret NC, Ouwehand WH, Palmas W, Penninx BW, Pepine CJ, Pettinger M, Polak JF, Ramachandran VS, Ranchalis J, Redline S, Ridker PM, Rose LM, Scharnag H, Schork NJ, Shimbo D, Shuldiner AR, Srinivasan SR, Stolk RP, Taylor HA, Thorand B, Trip MD, van Duijn CM, Verschuren WM, Wijmenga C, Winkelmann BR, Wyatt S, Young JH, Boehm BO, Caulfield MJ, Chasman DI, Davidson KW, Doevendans PA, Fitzgerald GA, Gums JG, Hakonarson H, Hillege HL, Illig T, Jarvik GP, Johnson JA, Kastelein JJ, Koenig W, März W, Mitchell BD, Murray SS, Oldehinkel AJ, Rader DJ, Reilly MP, Reiner AP, Schadt EE, Silverstein RL, Snieder H, Stanton AV, Uitterlinden AG, van der Harst P, van der Schouw YT, Samani NJ, Johnson AD, Munroe PB, de Bakker PI, Zhu X, Levy D, Keating BJ, Asselbergs FW. Loci influencing blood pressure identified using a cardiovascular gene-centric array. Hum Mol Genet. 2013 Apr 15; 22(8):1663-78.View Related Profiles.

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PMID: 23303523; PMCID: PMC3657476; DOI: 10.1093/hmg/dds555;

Cohen KS, Cheng S, Larson MG, Cupples LA, McCabe EL, Wang YA, Ngwa JS, Martin RP, Klein RJ, Hashmi B, Ge Y, O'Donnell CJ, Vasan RS, Shaw SY, Wang TJ. Circulating CD34(+) progenitor cell frequency is associated with clinical and genetic factors. Blood. 2013 Feb 21; 121(8):e50-6.View Related Profiles.

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PMID: 23287867; PMCID: PMC3578962; DOI: 10.1182/blood-2012-05-424846;

Kaess BM, Vasan RS, Mitchell GF. Aortic stiffness and incident hypertension--reply. JAMA. 2013 Jan 2; 309(1):30.View Related Profiles.

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Berry SD, Ramachandran VS, Cawthon PM, Gona P, McLean RR, Cupples LA, Kiel DP. Procollagen type III N-terminal peptide (P3NP) and lean mass: a cross-sectional study. J Frailty Aging. 2013; 2(3):129-34.View Related Profiles.

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Preis SR, Pencina MJ, D'Agostino RB, Meigs JB, Vasan RS, Fox CS. Neck circumference and the development of cardiovascular disease risk factors in the Framingham Heart Study. Diabetes Care. 2013 Jan; 36(1):e3.View Related Profiles.

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PMID: 23264305; PMCID: PMC3526209; DOI: 10.2337/dc12-0738;

Glazer NL, Lyass A, Esliger DW, Blease SJ, Freedson PS, Massaro JM, Murabito JM, Vasan RS. Sustained and shorter bouts of physical activity are related to cardiovascular health. Med Sci Sports Exerc. 2013 Jan; 45(1):109-15.View Related Profiles.

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PMID: 22895372; PMCID: PMC4166425 ; DOI: 10.1249/MSS.0b013e31826beae5;

Fox ER, Musani SK, Barbalic M, Lin H, Yu B, Ogunyankin KO, Smith NL, Kutlar A, Glazer NL, Post WS, Paltoo DN, Dries DL, Farlow DN, Duarte CW, Kardia SL, Meyers KJ, Sun YV, Arnett DK, Patki AA, Sha J, Cui X, Samdarshi TE, Penman AD, Bibbins-Domingo K, Bužková P, Benjamin EJ, Bluemke DA, Morrison AC, Heiss G, Carr JJ, Tracy RP, Mosley TH, Taylor HA, Psaty BM, Heckbert SR, Cappola TP, Vasan RS. Genome-wide association study of cardiac structure and systolic function in African Americans: the Candidate Gene Association Resource (CARe) study. Circ Cardiovasc Genet. 2013 Feb; 6(1):37-46.View Related Profiles.

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PMID: 23275298; PMCID: PMC3591479; DOI: 10.1161/CIRCGENETICS.111.962365;

Ho JE, Lyass A, Lee DS, Vasan RS, Kannel WB, Larson MG, Levy D. Predictors of new-onset heart failure: differences in preserved versus reduced ejection fraction. Circ Heart Fail. 2013 Mar; 6(2):279-86.View Related Profiles.

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PMID: 23271790; PMCID: PMC3705220; DOI: 10.1161/CIRCHEARTFAILURE.112.972828;

Chen MH, Huang J, Chen WM, Larson MG, Fox CS, Vasan RS, Seshadri S, O'Donnell CJ, Yang Q. Using family-based imputation in genome-wide association studies with large complex pedigrees: the Framingham Heart Study. PLoS One. 2012; 7(12):e51589.View Related Profiles.

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PMID: 23284720; PMCID: PMC3524237; DOI: 10.1371/journal.pone.0051589;

Franzini M, Fornaciari I, Rong J, Larson MG, Passino C, Emdin M, Paolicchi A, Vasan RS. Correlates and reference limits of plasma gamma-glutamyltransferase fractions from the Framingham Heart Study. Clin Chim Acta. 2013 Feb 18; 417:19-25.View Related Profiles.

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PMID: 23247050; PMCID: PMC4154585; DOI: 10.1016/j.cca.2012.12.002;

Fox ER, Musani SK, Singh P, Bidulescu A, Nagarajarao HS, Samdarshi TE, Steffes MW, Wang TJ, Taylor HA, Vasan RS. Association of plasma B-type natriuretic peptide concentrations with longitudinal blood pressure tracking in African Americans: findings from the Jackson Heart Study. Hypertension. 2013 Jan; 61(1):48-54. PMID: 23184379; PMCID: PMC3521855; DOI: 10.1161/HYPERTENSIONAHA.112.197657;

Khan AM, Lubitz SA, Sullivan LM, Sun JX, Levy D, Vasan RS, Magnani JW, Ellinor PT, Benjamin EJ, Wang TJ. Low serum magnesium and the development of atrial fibrillation in the community: the Framingham Heart Study. Circulation. 2013 Jan 1; 127(1):33-8.View Related Profiles.

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PMID: 23172839; PMCID: PMC3541701; DOI: 10.1161/CIRCULATIONAHA.111.082511;

Porter SA, Pedley A, Massaro JM, Vasan RS, Hoffmann U, Fox CS. Aminotransferase levels are associated with cardiometabolic risk above and beyond visceral fat and insulin resistance: the Framingham Heart Study. Arterioscler Thromb Vasc Biol. 2013 Jan; 33(1):139-46.View Related Profiles.

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PMID: 23162012; PMCID: PMC3593729; DOI: 10.1161/ATVBAHA.112.300075;

Sinner MF, Wang N, Fox CS, Fontes JD, Rienstra M, Magnani JW, Vasan RS, Calderwood AH, Pencina M, Sullivan LM, Ellinor PT, Benjamin EJ. Relation of circulating liver transaminase concentrations to risk of new-onset atrial fibrillation. Am J Cardiol. 2013 Jan 15; 111(2):219-24.View Related Profiles.

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PMID: 23127690; PMCID: PMC3538882; DOI: 10.1016/j.amjcard.2012.09.021;

Cheng S, Xanthakis V, Sullivan LM, Vasan RS. Blood pressure tracking over the adult life course: patterns and correlates in the Framingham heart study. Hypertension. 2012 Dec; 60(6):1393-9.View Related Profiles.

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PMID: 23108660; PMCID: PMC3499677; DOI: 10.1161/HYPERTENSIONAHA.112.201780;

Jasuja GK, Travison TG, Davda M, Murabito JM, Basaria S, Zhang A, Kushnir MM, Rockwood AL, Meikle W, Pencina MJ, Coviello A, Rose AJ, D'Agostino R, Vasan RS, Bhasin S. Age trends in estradiol and estrone levels measured using liquid chromatography tandem mass spectrometry in community-dwelling men of the Framingham Heart Study. J Gerontol A Biol Sci Med Sci. 2013 Jun; 68(6):733-40.View Related Profiles.

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PMID: 23105044; PMCID: PMC3660115; DOI: 10.1093/gerona/gls216;

Coglianese EE, Larson MG, Vasan RS, Ho JE, Ghorbani A, McCabe EL, Cheng S, Fradley MG, Kretschman D, Gao W, O'Connor G, Wang TJ, Januzzi JL. Distribution and clinical correlates of the interleukin receptor family member soluble ST2 in the Framingham Heart Study. Clin Chem. 2012 Dec; 58(12):1673-81.View Related Profiles.

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PMID: 23065477; PMCID: PMC3557515; DOI: 10.1373/clinchem.2012.192153;

Kaptoge S, Di Angelantonio E, Pennells L, Wood AM, White IR, Gao P, Walker M, Thompson A, Sarwar N, Caslake M, Butterworth AS, Amouyel P, Assmann G, Bakker SJ, Barr EL, Barrett-Connor E, Benjamin EJ, Björkelund C, Brenner H, Brunner E, Clarke R, Cooper JA, Cremer P, Cushman M, Dagenais GR, D'Agostino RB, Dankner R, Davey-Smith G, Deeg D, Dekker JM, Engström G, Folsom AR, Fowkes FG, Gallacher J, Gaziano JM, Giampaoli S, Gillum RF, Hofman A, Howard BV, Ingelsson E, Iso H, Jørgensen T, Kiechl S, Kitamura A, Kiyohara Y, Koenig W, Kromhout D, Kuller LH, Lawlor DA, Meade TW, Nissinen A, Nordestgaard BG, Onat A, Panagiotakos DB, Psaty BM, Rodriguez B, Rosengren A, Salomaa V, Kauhanen J, Salonen JT, Shaffer JA, Shea S, Ford I, Stehouwer CD, Strandberg TE, Tipping RW, Tosetto A, Wassertheil-Smoller S, Wennberg P, Westendorp RG, Whincup PH, Wilhelmsen L, Woodward M, Lowe GD, Wareham NJ, Khaw KT, Sattar N, Packard CJ, Gudnason V, Ridker PM, Pepys MB, Thompson SG, Danesh J. C-reactive protein, fibrinogen, and cardiovascular disease prediction. N Engl J Med. 2012 Oct 4; 367(14):1310-20.View Related Profiles.

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PMID: 23034020; PMCID: PMC3714101; DOI: 10.1056/NEJMoa1107477;

Ho JE, Mahajan A, Chen MH, Larson MG, McCabe EL, Ghorbani A, Cheng S, Johnson AD, Lindgren CM, Kempf T, Lind L, Ingelsson E, Vasan RS, Januzzi J, Wollert KC, Morris AP, Wang TJ. Clinical and genetic correlates of growth differentiation factor 15 in the community. Clin Chem. 2012 Nov; 58(11):1582-91.View Related Profiles.

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Bick AG, Flannick J, Ito K, Cheng S, Vasan RS, Parfenov MG, Herman DS, DePalma SR, Gupta N, Gabriel SB, Funke BH, Rehm HL, Benjamin EJ, Aragam J, Taylor HA, Fox ER, Newton-Cheh C, Kathiresan S, O'Donnell CJ, Wilson JG, Altshuler DM, Hirschhorn JN, Seidman JG, Seidman C. Burden of rare sarcomere gene variants in the Framingham and Jackson Heart Study cohorts. Am J Hum Genet. 2012 Sep 7; 91(3):513-9.View Related Profiles.

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PMID: 22958901; PMCID: PMC3511985; DOI: 10.1016/j.ajhg.2012.07.017;

Kaess BM, Rong J, Larson MG, Hamburg NM, Vita JA, Levy D, Benjamin EJ, Vasan RS, Mitchell GF. Aortic stiffness, blood pressure progression, and incident hypertension. JAMA. 2012 Sep 5; 308(9):875-81.View Related Profiles.

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PMID: 22948697; PMCID: PMC3594687; DOI: 10.1001/2012.jama.10503;

Liu C, Yang Q, Hwang SJ, Sun F, Johnson AD, Shirihai OS, Vasan RS, Levy D, Schwartz F. Association of genetic variation in the mitochondrial genome with blood pressure and metabolic traits. Hypertension. 2012 Oct; 60(4):949-56.View Related Profiles.

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PMID: 22949535; PMCID: PMC3753106; DOI: 10.1161/HYPERTENSIONAHA.112.196519;

Xanthakis V, Vasan RS. Improving cardiovascular health in women & children around the world. Indian J Med Res. 2012 Sep; 136(3):359-61.View Related Profiles.

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Ho JE, Liu C, Lyass A, Courchesne P, Pencina MJ, Vasan RS, Larson MG, Levy D. Galectin-3, a marker of cardiac fibrosis, predicts incident heart failure in the community. J Am Coll Cardiol. 2012 Oct 2; 60(14):1249-56.View Related Profiles.

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PMID: 22939561; PMCID: PMC3512095; DOI: 10.1016/j.jacc.2012.04.053;

Wang TJ, Wollert KC, Larson MG, Coglianese E, McCabe EL, Cheng S, Ho JE, Fradley MG, Ghorbani A, Xanthakis V, Kempf T, Benjamin EJ, Levy D, Vasan RS, Januzzi JL. Prognostic utility of novel biomarkers of cardiovascular stress: the Framingham Heart Study. Circulation. 2012 Sep 25; 126(13):1596-604.View Related Profiles.

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PMID: 22907935; PMCID: PMC3656719; DOI: 10.1161/CIRCULATIONAHA.112.129437;

Kaess BM, Enserro DM, McManus DD, Xanthakis V, Chen MH, Sullivan LM, Ingram C, O'Donnell CJ, Keaney JF, Vasan RS, Glazer NL. Cardiometabolic correlates and heritability of fetuin-A, retinol-binding protein 4, and fatty-acid binding protein 4 in the Framingham Heart Study. J Clin Endocrinol Metab. 2012 Oct; 97(10):E1943-7.View Related Profiles.

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PMID: 22855337; PMCID: PMC3674297; DOI: 10.1210/jc.2012-1458;

Haring R, Friedrich N, Völzke H, Vasan RS, Felix SB, Dörr M, Meyer zu Schwabedissen HE, Nauck M, Wallaschofski H. Positive association of serum prolactin concentrations with all-cause and cardiovascular mortality. Eur Heart J. 2014 May; 35(18):1215-21. PMID: 22843444; DOI: 10.1093/eurheartj/ehs233;

Adult height and the risk of cause-specific death and vascular morbidity in 1 million people: individual participant meta-analysis. Int J Epidemiol. 2012 Oct; 41(5):1419-33. PMID: 22825588; PMCID: PMC3465767; DOI: 10.1093/ije/dys086;

Coviello AD, Haring R, Wellons M, Vaidya D, Lehtimäki T, Keildson S, Lunetta KL, He C, Fornage M, Lagou V, Mangino M, Onland-Moret NC, Chen B, Eriksson J, Garcia M, Liu YM, Koster A, Lohman K, Lyytikäinen LP, Petersen AK, Prescott J, Stolk L, Vandenput L, Wood AR, Zhuang WV, Ruokonen A, Hartikainen AL, Pouta A, Bandinelli S, Biffar R, Brabant G, Cox DG, Chen Y, Cummings S, Ferrucci L, Gunter MJ, Hankinson SE, Martikainen H, Hofman A, Homuth G, Illig T, Jansson JO, Johnson AD, Karasik D, Karlsson M, Kettunen J, Kiel DP, Kraft P, Liu J, Ljunggren Ö, Lorentzon M, Maggio M, Markus MR, Mellström D, Miljkovic I, Mirel D, Nelson S, Morin Papunen L, Peeters PH, Prokopenko I, Raffel L, Reincke M, Reiner AP, Rexrode K, Rivadeneira F, Schwartz SM, Siscovick D, Soranzo N, Stöckl D, Tworoger S, Uitterlinden AG, van Gils CH, Vasan RS, Wichmann HE, Zhai G, Bhasin S, Bidlingmaier M, Chanock SJ, De Vivo I, Harris TB, Hunter DJ, Kähönen M, Liu S, Ouyang P, Spector TD, van der Schouw YT, Viikari J, Wallaschofski H, McCarthy MI, Frayling TM, Murray A, Franks S, Järvelin MR, de Jong FH, Raitakari O, Teumer A, Ohlsson C, Murabito JM, Perry JR. A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation. PLoS Genet. 2012; 8(7):e1002805.View Related Profiles.

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PMID: 22829776; PMCID: PMC3400553; DOI: 10.1371/journal.pgen.1002805;

Dallmeier D, Larson MG, Vasan RS, Keaney JF, Fontes JD, Meigs JB, Fox CS, Benjamin EJ. Metabolic syndrome and inflammatory biomarkers: a community-based cross-sectional study at the Framingham Heart Study. Diabetol Metab Syndr. 2012; 4(1):28.View Related Profiles.

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PMID: 22716219; PMCID: PMC3547735; DOI: 10.1186/1758-5996-4-28;

Harris WS, Pottala JV, Lacey SM, Vasan RS, Larson MG, Robins SJ. Clinical correlates and heritability of erythrocyte eicosapentaenoic and docosahexaenoic acid content in the Framingham Heart Study. Atherosclerosis. 2012 Dec; 225(2):425-31.View Related Profiles.

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PMID: 22727409; PMCID: PMC3593234; DOI: 10.1016/j.atherosclerosis.2012.05.030;

Haring R, Xanthakis V, Coviello A, Sullivan L, Bhasin S, Wallaschofski H, Murabito JM, Vasan RS. Clinical correlates of sex steroids and gonadotropins in men over the late adulthood: the Framingham Heart Study. Int J Androl. 2012 Dec; 35(6):775-82.View Related Profiles.

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PMID: 22640232; PMCID: PMC3434249; DOI: 10.1111/j.1365-2605.2012.01285.x;

Harris WS, Pottala JV, Vasan RS, Larson MG, Robins SJ. Changes in erythrocyte membrane trans and marine fatty acids between 1999 and 2006 in older Americans. J Nutr. 2012 Jul; 142(7):1297-303.View Related Profiles.

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PMID: 22623386; PMCID: PMC3374668; DOI: 10.3945/jn.112.158295;

Thanassoulis G, Lyass A, Benjamin EJ, Larson MG, Vita JA, Levy D, Hamburg NM, Widlansky ME, O'Donnell CJ, Mitchell GF, Vasan RS. Relations of exercise blood pressure response to cardiovascular risk factors and vascular function in the Framingham Heart Study. Circulation. 2012 Jun 12; 125(23):2836-43.View Related Profiles.

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PMID: 22572915; PMCID: PMC3636551; DOI: 10.1161/CIRCULATIONAHA.111.063933;

Ho JE, Gona P, Pencina MJ, Tu JV, Austin PC, Vasan RS, Kannel WB, D'Agostino RB, Lee DS, Levy D. Discriminating clinical features of heart failure with preserved vs. reduced ejection fraction in the community. Eur Heart J. 2012 Jul; 33(14):1734-41.View Related Profiles.

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PMID: 22507977; PMCID: PMC3530391; DOI: 10.1093/eurheartj/ehs070;

Cheng S, Rhee EP, Larson MG, Lewis GD, McCabe EL, Shen D, Palma MJ, Roberts LD, Dejam A, Souza AL, Deik AA, Magnusson M, Fox CS, O'Donnell CJ, Vasan RS, Melander O, Clish CB, Gerszten RE, Wang TJ. Metabolite profiling identifies pathways associated with metabolic risk in humans. Circulation. 2012 May 8; 125(18):2222-31.View Related Profiles.

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PMID: 22496159; PMCID: PMC3376658; DOI: 10.1161/CIRCULATIONAHA.111.067827;

O'Seaghdha CM, Hwang SJ, Vasan RS, Larson MG, Hoffmann U, Wang TJ, Fox CS. Correlation of renin angiotensin and aldosterone system activity with subcutaneous and visceral adiposity: the framingham heart study. BMC Endocr Disord. 2012; 12:3.View Related Profiles.

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PMID: 22475205; PMCID: PMC3352034; DOI: 10.1186/1472-6823-12-3;

Pikula A, Beiser AS, DeCarli C, Himali JJ, Debette S, Au R, Selhub J, Toffler GH, Wang TJ, Meigs JB, Kelly-Hayes M, Kase CS, Wolf PA, Vasan RS, Seshadri S. Multiple biomarkers and risk of clinical and subclinical vascular brain injury: the Framingham Offspring Study. Circulation. 2012 May 1; 125(17):2100-7.View Related Profiles.

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PMID: 22456473; PMCID: PMC3427730; DOI: 10.1161/CIRCULATIONAHA.110.989145;

Tan ZS, Harris WS, Beiser AS, Au R, Himali JJ, Debette S, Pikula A, Decarli C, Wolf PA, Vasan RS, Robins SJ, Seshadri S. Red blood cell ?-3 fatty acid levels and markers of accelerated brain aging. Neurology. 2012 Feb 28; 78(9):658-64.View Related Profiles.

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PMID: 22371413; PMCID: PMC3286229; DOI: 10.1212/WNL.0b013e318249f6a9;

Zachariah JP, Xanthakis V, Larson MG, Vita JA, Sullivan LM, Smith HM, Safa R, Peng X, Hamburg N, Levy D, Sawyer DB, Mitchell GF, Vasan RS. Circulating vascular growth factors and central hemodynamic load in the community. Hypertension. 2012 Apr; 59(4):773-9.View Related Profiles.

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PMID: 22371357; PMCID: PMC3336212; DOI: 10.1161/HYPERTENSIONAHA.111.179242;

Haring R, Völzke H, Vasan RS, Felix SB, Nauck M, Dörr M, Wallaschofski H. Sex-specific associations of serum prolactin concentrations with cardiac remodeling: longitudinal results from the Study of Health Pomerania (SHIP). Atherosclerosis. 2012 Apr; 221(2):570-6. PMID: 22293228; DOI: 10.1016/j.atherosclerosis.2012.01.017;

Kaess BM, Pedley A, Massaro JM, Larson MG, Corsini E, Hoffmann U, Smith HM, Sawyer DB, Vasan RS, Fox CS. Relation of vascular growth factors with CT-derived measures of body fat distribution: the Framingham Heart Study. J Clin Endocrinol Metab. 2012 Mar; 97(3):987-94.View Related Profiles.

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PMID: 22170711; PMCID: PMC3319207; DOI: 10.1210/jc.2011-2310;

Dhingra R, Vasan RS. Age as a risk factor. Med Clin North Am. 2012 Jan; 96(1):87-91. PMID: 22391253; PMCID: PMC3297980; DOI: 10.1016/j.mcna.2011.11.003;

Rienstra M, Sun JX, Lubitz SA, Frankel DS, Vasan RS, Levy D, Magnani JW, Sullivan LM, Meigs JB, Ellinor PT, Benjamin EJ. Plasma resistin, adiponectin, and risk of incident atrial fibrillation: the Framingham Offspring Study. Am Heart J. 2012 Jan; 163(1):119-124.e1.View Related Profiles.

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PMID: 22172445; PMCID: PMC3375331; DOI: 10.1016/j.ahj.2011.09.029;

Cheng S, Vasan RS. Advances in the epidemiology of heart failure and left ventricular remodeling. Circulation. 2011 Nov 15; 124(20):e516-9. PMID: 22083151; PMCID: PMC3621875; DOI: 10.1161/CIRCULATIONAHA.111.070235;

Mitchell GF, Verwoert GC, Tarasov KV, Isaacs A, Smith AV, Yasmin, Rietzschel ER, Tanaka T, Liu Y, Parsa A, Najjar SS, O'Shaughnessy KM, Sigurdsson S, De Buyzere ML, Larson MG, Sie MP, Andrews JS, Post WS, Mattace-Raso FU, McEniery CM, Eiriksdottir G, Segers P, Vasan RS, van Rijn MJ, Howard TD, McArdle PF, Dehghan A, Jewell ES, Newhouse SJ, Bekaert S, Hamburg NM, Newman AB, Hofman A, Scuteri A, De Bacquer D, Ikram MA, Psaty BM, Fuchsberger C, Olden M, Wain LV, Elliott P, Smith NL, Felix JF, Erdmann J, Vita JA, Sutton-Tyrrell K, Sijbrands EJ, Sanna S, Launer LJ, De Meyer T, Johnson AD, Schut AF, Herrington DM, Rivadeneira F, Uda M, Wilkinson IB, Aspelund T, Gillebert TC, Van Bortel L, Benjamin EJ, Oostra BA, Ding J, Gibson Q, Uitterlinden AG, Abecasis GR, Cockcroft JR, Gudnason V, De Backer GG, Ferrucci L, Harris TB, Shuldiner AR, van Duijn CM, Levy D, Lakatta EG, Witteman JC. Common genetic variation in the 3'-BCL11B gene desert is associated with carotid-femoral pulse wave velocity and excess cardiovascular disease risk: the AortaGen Consortium. Circ Cardiovasc Genet. 2012 Feb 1; 5(1):81-90.View Related Profiles.

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PMID: 22068335; PMCID: PMC3288392; DOI: 10.1161/CIRCGENETICS.111.959817;

Lüneburg N, Xanthakis V, Schwedhelm E, Sullivan LM, Maas R, Anderssohn M, Riederer U, Glazer NL, Vasan RS, Böger RH. Reference intervals for plasma L-arginine and the L-arginine:asymmetric dimethylarginine ratio in the Framingham Offspring Cohort. J Nutr. 2011 Dec; 141(12):2186-90.View Related Profiles.

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PMID: 22031661; PMCID: PMC3223876; DOI: 10.3945/jn.111.148197;

Cheng S, Wang N, Larson MG, Palmisano JN, Mitchell GF, Benjamin EJ, Vasan RS, Levy D, McCabe EL, Vita JA, Wang TJ, Shaw SY, Cohen KS, Hamburg NM. Circulating angiogenic cell populations, vascular function, and arterial stiffness. Atherosclerosis. 2012 Jan; 220(1):145-50.View Related Profiles.

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PMID: 22093724; PMCID: PMC3277804; DOI: 10.1016/j.atherosclerosis.2011.10.015;

Chambers JC, Zhang W, Sehmi J, Li X, Wass MN, Van der Harst P, Holm H, Sanna S, Kavousi M, Baumeister SE, Coin LJ, Deng G, Gieger C, Heard-Costa NL, Hottenga JJ, Kühnel B, Kumar V, Lagou V, Liang L, Luan J, Vidal PM, Mateo Leach I, O'Reilly PF, Peden JF, Rahmioglu N, Soininen P, Speliotes EK, Yuan X, Thorleifsson G, Alizadeh BZ, Atwood LD, Borecki IB, Brown MJ, Charoen P, Cucca F, Das D, de Geus EJ, Dixon AL, Döring A, Ehret G, Eyjolfsson GI, Farrall M, Forouhi NG, Friedrich N, Goessling W, Gudbjartsson DF, Harris TB, Hartikainen AL, Heath S, Hirschfield GM, Hofman A, Homuth G, Hyppönen E, Janssen HL, Johnson T, Kangas AJ, Kema IP, Kühn JP, Lai S, Lathrop M, Lerch MM, Li Y, Liang TJ, Lin JP, Loos RJ, Martin NG, Moffatt MF, Montgomery GW, Munroe PB, Musunuru K, Nakamura Y, O'Donnell CJ, Olafsson I, Penninx BW, Pouta A, Prins BP, Prokopenko I, Puls R, Ruokonen A, Savolainen MJ, Schlessinger D, Schouten JN, Seedorf U, Sen-Chowdhry S, Siminovitch KA, Smit JH, Spector TD, Tan W, Teslovich TM, Tukiainen T, Uitterlinden AG, Van der Klauw MM, Vasan RS, Wallace C, Wallaschofski H, Wichmann HE, Willemsen G, Würtz P, Xu C, Yerges-Armstrong LM, Abecasis GR, Ahmadi KR, Boomsma DI, Caulfield M, Cookson WO, van Duijn CM, Froguel P, Matsuda K, McCarthy MI, Meisinger C, Mooser V, Pietiläinen KH, Schumann G, Snieder H, Sternberg MJ, Stolk RP, Thomas HC, Thorsteinsdottir U, Uda M, Waeber G, Wareham NJ, Waterworth DM, Watkins H, Whitfield JB, Witteman JC, Wolffenbuttel BH, Fox CS, Ala-Korpela M, Stefansson K, Vollenweider P, Völzke H, Schadt EE, Scott J, Järvelin MR, Elliott P, Kooner JS. Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. Nat Genet. 2011 Nov; 43(11):1131-8.View Related Profiles.

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PMID: 22001757; PMCID: PMC3482372; DOI: 10.1038/ng.970;

Grallert H, Dupuis J, Bis JC, Dehghan A, Barbalic M, Baumert J, Lu C, Smith NL, Uitterlinden AG, Roberts R, Khuseyinova N, Schnabel RB, Rice KM, Rivadeneira F, Hoogeveen RC, Fontes JD, Meisinger C, Keaney JF, Lemaitre R, Aulchenko YS, Vasan RS, Ellis S, Hazen SL, van Duijn CM, Nelson JJ, März W, Schunkert H, McPherson RM, Stirnadel-Farrant HA, Psaty BM, Gieger C, Siscovick D, Hofman A, Illig T, Cushman M, Yamamoto JF, Rotter JI, Larson MG, Stewart AF, Boerwinkle E, Witteman JC, Tracy RP, Koenig W, Benjamin EJ, Ballantyne CM. Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies. Eur Heart J. 2012 Jan; 33(2):238-51.View Related Profiles.

Benjamin, Emelia
Dupuis, Josee
Larson, Martin
Ramachandran, Vasan

PMID: 22003152; PMCID: PMC3258449; DOI: 10.1093/eurheartj/ehr372;

Dhingra R, Vasan RS. Diabetes and the risk of heart failure. Heart Fail Clin. 2012 Jan; 8(1):125-33. PMID: 22108732; PMCID: PMC3223386; DOI: 10.1016/j.hfc.2011.08.008;

Coglianese EE, Qureshi MM, Vasan RS, Wang TJ, Moore LL. Usefulness of the blood hematocrit level to predict development of heart failure in a community. Am J Cardiol. 2012 Jan 15; 109(2):241-5.View Related Profiles.

Moore, Lynn
Qureshi, Muhammad
Ramachandran, Vasan

PMID: 21996141; PMCID: PMC3663594; DOI: 10.1016/j.amjcard.2011.08.037;

Fontes JD, Lyass A, Massaro JM, Rienstra M, Dallmeier D, Schnabel RB, Wang TJ, Vasan RS, Lubitz SA, Magnani JW, Levy D, Ellinor PT, Fox CS, Benjamin EJ. Insulin resistance and atrial fibrillation (from the Framingham Heart Study). Am J Cardiol. 2012 Jan 1; 109(1):87-90.View Related Profiles.

Dallmeier Rojas, Dhayana
Benjamin, Emelia
Magnani, Jared
Massaro, Joseph
Ramachandran, Vasan

PMID: 21996140; PMCID: PMC3242834; DOI: 10.1016/j.amjcard.2011.08.008;

Ohlsson C, Wallaschofski H, Lunetta KL, Stolk L, Perry JR, Koster A, Petersen AK, Eriksson J, Lehtimäki T, Huhtaniemi IT, Hammond GL, Maggio M, Coviello AD, Ferrucci L, Heier M, Hofman A, Holliday KL, Jansson JO, Kähönen M, Karasik D, Karlsson MK, Kiel DP, Liu Y, Ljunggren O, Lorentzon M, Lyytikäinen LP, Meitinger T, Mellström D, Melzer D, Miljkovic I, Nauck M, Nilsson M, Penninx B, Pye SR, Vasan RS, Reincke M, Rivadeneira F, Tajar A, Teumer A, Uitterlinden AG, Ulloor J, Viikari J, Völker U, Völzke H, Wichmann HE, Wu TS, Zhuang WV, Ziv E, Wu FC, Raitakari O, Eriksson A, Bidlingmaier M, Harris TB, Murray A, de Jong FH, Murabito JM, Bhasin S, Vandenput L, Haring R. Genetic determinants of serum testosterone concentrations in men. PLoS Genet. 2011 Oct; 7(10):e1002313.View Related Profiles.

Coviello, Andrea
Ulloor, Jagadish
Murabito, Joanne
Lunetta, Kathryn
Bhasin, Shalender
Ramachandran, Vasan

PMID: 21998597; PMCID: PMC3188559; DOI: 10.1371/journal.pgen.1002313;

Large-scale gene-centric analysis identifies novel variants for coronary artery disease. PLoS Genet. 2011 Sep; 7(9):e1002260.View Related Profiles.

Cupples, L
Ramachandran, Vasan

PMID: 21966275; PMCID: PMC3178591; DOI: 10.1371/journal.pgen.1002260;

Haring R, Travison TG, Bhasin S, Vasan RS, Wallaschofski H, Davda MN, Coviello A, Murabito JM. Relation between sex hormone concentrations, peripheral arterial disease, and change in ankle-brachial index: findings from the Framingham Heart Study. J Clin Endocrinol Metab. 2011 Dec; 96(12):3724-32.View Related Profiles.

Coviello, Andrea
Murabito, Joanne
Bhasin, Shalender
Travison, Thomas
Ramachandran, Vasan

PMID: 21937625; PMCID: PMC3232625; DOI: 10.1210/jc.2011-1068;

Bhasin S, Jasjua GK, Pencina M, D'Agostino R, Coviello AD, Vasan RS, Travison TG. Sex hormone-binding globulin, but not testosterone, is associated prospectively and independently with incident metabolic syndrome in men: the framingham heart study. Diabetes Care. 2011 Nov; 34(11):2464-70.View Related Profiles.

Coviello, Andrea
Pencina, Michael
D'Agostino, Ralph
Bhasin, Shalender
Travison, Thomas
Ramachandran, Vasan

PMID: 21926281; PMCID: PMC3198304; DOI: 10.2337/dc11-0888;

Ehret GB, Munroe PB, Rice KM, Bochud M, Johnson AD, Chasman DI, Smith AV, Tobin MD, Verwoert GC, Hwang SJ, Pihur V, Vollenweider P, O'Reilly PF, Amin N, Bragg-Gresham JL, Teumer A, Glazer NL, Launer L, Zhao JH, Aulchenko Y, Heath S, Sõber S, Parsa A, Luan J, Arora P, Dehghan A, Zhang F, Lucas G, Hicks AA, Jackson AU, Peden JF, Tanaka T, Wild SH, Rudan I, Igl W, Milaneschi Y, Parker AN, Fava C, Chambers JC, Fox ER, Kumari M, Go MJ, van der Harst P, Kao WH, Sjögren M, Vinay DG, Alexander M, Tabara Y, Shaw-Hawkins S, Whincup PH, Liu Y, Shi G, Kuusisto J, Tayo B, Seielstad M, Sim X, Nguyen KD, Lehtimäki T, Matullo G, Wu Y, Gaunt TR, Onland-Moret NC, Cooper MN, Platou CG, Org E, Hardy R, Dahgam S, Palmen J, Vitart V, Braund PS, Kuznetsova T, Uiterwaal CS, Adeyemo A, Palmas W, Campbell H, Ludwig B, Tomaszewski M, Tzoulaki I, Palmer ND, Aspelund T, Garcia M, Chang YP, O'Connell JR, Steinle NI, Grobbee DE, Arking DE, Kardia SL, Morrison AC, Hernandez D, Najjar S, McArdle WL, Hadley D, Brown MJ, Connell JM, Hingorani AD, Day IN, Lawlor DA, Beilby JP, Lawrence RW, Clarke R, Hopewell JC, Ongen H, Dreisbach AW, Li Y, Young JH, Bis JC, Kähönen M, Viikari J, Adair LS, Lee NR, Chen MH, Olden M, Pattaro C, Bolton JA, Köttgen A, Bergmann S, Mooser V, Chaturvedi N, Frayling TM, Islam M, Jafar TH, Erdmann J, Kulkarni SR, Bornstein SR, Grässler J, Groop L, Voight BF, Kettunen J, Howard P, Taylor A, Guarrera S, Ricceri F, Emilsson V, Plump A, Barroso I, Khaw KT, Weder AB, Hunt SC, Sun YV, Bergman RN, Collins FS, Bonnycastle LL, Scott LJ, Stringham HM, Peltonen L, Perola M, Vartiainen E, Brand SM, Staessen JA, Wang TJ, Burton PR, Soler Artigas M, Dong Y, Snieder H, Wang X, Zhu H, Lohman KK, Rudock ME, Heckbert SR, Smith NL, Wiggins KL, Doumatey A, Shriner D, Veldre G, Viigimaa M, Kinra S, Prabhakaran D, Tripathy V, Langefeld CD, Rosengren A, Thelle DS, Corsi AM, Singleton A, Forrester T, Hilton G, McKenzie CA, Salako T, Iwai N, Kita Y, Ogihara T, Ohkubo T, Okamura T, Ueshima H, Umemura S, Eyheramendy S, Meitinger T, Wichmann HE, Cho YS, Kim HL, Lee JY, Scott J, Sehmi JS, Zhang W, Hedblad B, Nilsson P, Smith GD, Wong A, Narisu N, Stancáková A, Raffel LJ, Yao J, Kathiresan S, O'Donnell CJ, Schwartz SM, Ikram MA, Longstreth WT, Mosley TH, Seshadri S, Shrine NR, Wain LV, Morken MA, Swift AJ, Laitinen J, Prokopenko I, Zitting P, Cooper JA, Humphries SE, Danesh J, Rasheed A, Goel A, Hamsten A, Watkins H, Bakker SJ, van Gilst WH, Janipalli CS, Mani KR, Yajnik CS, Hofman A, Mattace-Raso FU, Oostra BA, Demirkan A, Isaacs A, Rivadeneira F, Lakatta EG, Orru M, Scuteri A, Ala-Korpela M, Kangas AJ, Lyytikäinen LP, Soininen P, Tukiainen T, Würtz P, Ong RT, Dörr M, Kroemer HK, Völker U, Völzke H, Galan P, Hercberg S, Lathrop M, Zelenika D, Deloukas P, Mangino M, Spector TD, Zhai G, Meschia JF, Nalls MA, Sharma P, Terzic J, Kumar MV, Denniff M, Zukowska-Szczechowska E, Wagenknecht LE, Fowkes FG, Charchar FJ, Schwarz PE, Hayward C, Guo X, Rotimi C, Bots ML, Brand E, Samani NJ, Polasek O, Talmud PJ, Nyberg F, Kuh D, Laan M, Hveem K, Palmer LJ, van der Schouw YT, Casas JP, Mohlke KL, Vineis P, Raitakari O, Ganesh SK, Wong TY, Tai ES, Cooper RS, Laakso M, Rao DC, Harris TB, Morris RW, Dominiczak AF, Kivimaki M, Marmot MG, Miki T, Saleheen D, Chandak GR, Coresh J, Navis G, Salomaa V, Han BG, Zhu X, Kooner JS, Melander O, Ridker PM, Bandinelli S, Gyllensten UB, Wright AF, Wilson JF, Ferrucci L, Farrall M, Tuomilehto J, Pramstaller PP, Elosua R, Soranzo N, Sijbrands EJ, Altshuler D, Loos RJ, Shuldiner AR, Gieger C, Meneton P, Uitterlinden AG, Wareham NJ, Gudnason V, Rotter JI, Rettig R, Uda M, Strachan DP, Witteman JC, Hartikainen AL, Beckmann JS, Boerwinkle E, Vasan RS, Boehnke M, Larson MG, Järvelin MR, Psaty BM, Abecasis GR, Chakravarti A, Elliott P, van Duijn CM, Newton-Cheh C, Levy D, Caulfield MJ, Johnson T. Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature. 2011 Oct 6; 478(7367):103-9.View Related Profiles.

O'Donnell, Christopher
Cupples, L
Larson, Martin
Chen, Ming-Huei
Myers, Richard
Hwang, Shih-Jen
Seshadri, Sudha
Ramachandran, Vasan

PMID: 21909115; PMCID: PMC3340926; DOI: 10.1038/nature10405;

Wain LV, Verwoert GC, O'Reilly PF, Shi G, Johnson T, Johnson AD, Bochud M, Rice KM, Henneman P, Smith AV, Ehret GB, Amin N, Larson MG, Mooser V, Hadley D, Dörr M, Bis JC, Aspelund T, Esko T, Janssens AC, Zhao JH, Heath S, Laan M, Fu J, Pistis G, Luan J, Arora P, Lucas G, Pirastu N, Pichler I, Jackson AU, Webster RJ, Zhang F, Peden JF, Schmidt H, Tanaka T, Campbell H, Igl W, Milaneschi Y, Hottenga JJ, Vitart V, Chasman DI, Trompet S, Bragg-Gresham JL, Alizadeh BZ, Chambers JC, Guo X, Lehtimäki T, Kühnel B, Lopez LM, Polašek O, Boban M, Nelson CP, Morrison AC, Pihur V, Ganesh SK, Hofman A, Kundu S, Mattace-Raso FU, Rivadeneira F, Sijbrands EJ, Uitterlinden AG, Hwang SJ, Vasan RS, Wang TJ, Bergmann S, Vollenweider P, Waeber G, Laitinen J, Pouta A, Zitting P, McArdle WL, Kroemer HK, Völker U, Völzke H, Glazer NL, Taylor KD, Harris TB, Alavere H, Haller T, Keis A, Tammesoo ML, Aulchenko Y, Barroso I, Khaw KT, Galan P, Hercberg S, Lathrop M, Eyheramendy S, Org E, Sõber S, Lu X, Nolte IM, Penninx BW, Corre T, Masciullo C, Sala C, Groop L, Voight BF, Melander O, O'Donnell CJ, Salomaa V, d'Adamo AP, Fabretto A, Faletra F, Ulivi S, Del Greco F, Facheris M, Collins FS, Bergman RN, Beilby JP, Hung J, Musk AW, Mangino M, Shin SY, Soranzo N, Watkins H, Goel A, Hamsten A, Gider P, Loitfelder M, Zeginigg M, Hernandez D, Najjar SS, Navarro P, Wild SH, Corsi AM, Singleton A, de Geus EJ, Willemsen G, Parker AN, Rose LM, Buckley B, Stott D, Orru M, Uda M, van der Klauw MM, Zhang W, Li X, Scott J, Chen YD, Burke GL, Kähönen M, Viikari J, Döring A, Meitinger T, Davies G, Starr JM, Emilsson V, Plump A, Lindeman JH, Hoen PA, König IR, Felix JF, Clarke R, Hopewell JC, Ongen H, Breteler M, Debette S, Destefano AL, Fornage M, Mitchell GF, Smith NL, Holm H, Stefansson K, Thorleifsson G, Thorsteinsdottir U, Samani NJ, Preuss M, Rudan I, Hayward C, Deary IJ, Wichmann HE, Raitakari OT, Palmas W, Kooner JS, Stolk RP, Jukema JW, Wright AF, Boomsma DI, Bandinelli S, Gyllensten UB, Wilson JF, Ferrucci L, Schmidt R, Farrall M, Spector TD, Palmer LJ, Tuomilehto J, Pfeufer A, Gasparini P, Siscovick D, Altshuler D, Loos RJ, Toniolo D, Snieder H, Gieger C, Meneton P, Wareham NJ, Oostra BA, Metspalu A, Launer L, Rettig R, Strachan DP, Beckmann JS, Witteman JC, Erdmann J, van Dijk KW, Boerwinkle E, Boehnke M, Ridker PM, Jarvelin MR, Chakravarti A, Abecasis GR, Gudnason V, Newton-Cheh C, Levy D, Munroe PB, Psaty BM, Caulfield MJ, Rao DC, Tobin MD, Elliott P, van Duijn CM. Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet. 2011 Oct; 43(10):1005-11.View Related Profiles.

DeStefano, Anita
O'Donnell, Christopher
Larson, Martin
Hwang, Shih-Jen
Ramachandran, Vasan

PMID: 21909110; PMCID: PMC3445021; DOI: 10.1038/ng.922;

Schwedhelm E, Xanthakis V, Maas R, Sullivan LM, Atzler D, Lüneburg N, Glazer NL, Riederer U, Vasan RS, Böger RH. Plasma symmetric dimethylarginine reference limits from the Framingham offspring cohort. Clin Chem Lab Med. 2011 Nov; 49(11):1907-10.View Related Profiles.

Sullivan, Lisa
Xanthakis, Vanessa
Ramachandran, Vasan

PMID: 21864208; PMCID: PMC3235736; DOI: 10.1515/CCLM.2011.679;

Fradley MG, Larson MG, Cheng S, McCabe E, Coglianese E, Shah RV, Levy D, Vasan RS, Wang TJ. Reference limits for N-terminal-pro-B-type natriuretic peptide in healthy individuals (from the Framingham Heart Study). Am J Cardiol. 2011 Nov 1; 108(9):1341-5.View Related Profiles.

Larson, Martin
Ramachandran, Vasan

PMID: 21864812; PMCID: PMC3209520; DOI: 10.1016/j.amjcard.2011.06.057;

Khan AM, Cheng S, Magnusson M, Larson MG, Newton-Cheh C, McCabe EL, Coviello AD, Florez JC, Fox CS, Levy D, Robins SJ, Arora P, Bhasin S, Lam CS, Vasan RS, Melander O, Wang TJ. Cardiac natriuretic peptides, obesity, and insulin resistance: evidence from two community-based studies. J Clin Endocrinol Metab. 2011 Oct; 96(10):3242-9.View Related Profiles.

Coviello, Andrea
Larson, Martin
Robins, Sander
Bhasin, Shalender
Ramachandran, Vasan

PMID: 21849523; PMCID: PMC3200240; DOI: 10.1210/jc.2011-1182;

Fox ER, Musani SK, Bidulescu A, Nagarajarao HS, Samdarshi TE, Gebreab SY, Sung JH, Steffes MW, Wang TJ, Taylor HA, Vasan RS. Relation of obesity to circulating B-type natriuretic peptide concentrations in blacks: the Jackson Heart Study. Circulation. 2011 Aug 30; 124(9):1021-7. PMID: 21824924; PMCID: PMC3318977; DOI: 10.1161/CIRCULATIONAHA.110.991943;

Chen MH, Liu X, Wei F, Larson MG, Fox CS, Vasan RS, Yang Q. A comparison of strategies for analyzing dichotomous outcomes in genome-wide association studies with general pedigrees. Genet Epidemiol. 2011 Nov; 35(7):650-7.View Related Profiles.

Larson, Martin
Chen, Ming-Huei
Yang, Qiong
Ramachandran, Vasan

PMID: 21818773; PMCID: PMC3197768; DOI: 10.1002/gepi.20614;

Lam CS, Cheng S, Choong K, Larson MG, Murabito JM, Newton-Cheh C, Bhasin S, McCabe EL, Miller KK, Redfield MM, Vasan RS, Coviello AD, Wang TJ. Influence of sex and hormone status on circulating natriuretic peptides. J Am Coll Cardiol. 2011 Aug 2; 58(6):618-26.View Related Profiles.

Coviello, Andrea
Murabito, Joanne
Larson, Martin
Bhasin, Shalender
Ramachandran, Vasan

PMID: 21798425; PMCID: PMC3170816; DOI: 10.1016/j.jacc.2011.03.042;

MacRae CA, Vasan RS. Next-generation genome-wide association studies: time to focus on phenotype? Circ Cardiovasc Genet. 2011 Aug 1; 4(4):334-6. PMID: 21846867; PMCID: PMC3187849; DOI: 10.1161/CIRCGENETICS.111.960765;

Cheng S, Fox CS, Larson MG, Massaro JM, McCabe EL, Khan AM, Levy D, Hoffmann U, O'Donnell CJ, Miller KK, Newton-Cheh C, Coviello AD, Bhasin S, Vasan RS, Wang TJ. Relation of visceral adiposity to circulating natriuretic peptides in ambulatory individuals. Am J Cardiol. 2011 Oct 1; 108(7):979-84.View Related Profiles.

Coviello, Andrea
O'Donnell, Christopher
Massaro, Joseph
Larson, Martin
Bhasin, Shalender
Ramachandran, Vasan

PMID: 21813106; PMCID: PMC3175269; DOI: 10.1016/j.amjcard.2011.05.033;

Debette S, Visvikis-Siest S, Chen MH, Ndiaye NC, Song C, Destefano A, Safa R, Azimi Nezhad M, Sawyer D, Marteau JB, Xanthakis V, Siest G, Sullivan L, Pfister M, Smith H, Choi SH, Lamont J, Lind L, Yang Q, Fitzgerald P, Ingelsson E, Vasan RS, Seshadri S. Identification of cis- and trans-acting genetic variants explaining up to half the variation in circulating vascular endothelial growth factor levels. Circ Res. 2011 Aug 19; 109(5):554-63.View Related Profiles.

DeStefano, Anita
Sullivan, Lisa
Yang, Qiong
Choi, Seung Hoan
Seshadri, Sudha
Xanthakis, Vanessa
Ramachandran, Vasan

PMID: 21757650; PMCID: PMC3193930; DOI: 10.1161/CIRCRESAHA.111.243790;

Coviello AD, Zhuang WV, Lunetta KL, Bhasin S, Ulloor J, Zhang A, Karasik D, Kiel DP, Vasan RS, Murabito JM. Circulating testosterone and SHBG concentrations are heritable in women: the Framingham Heart Study. J Clin Endocrinol Metab. 2011 Sep; 96(9):E1491-5.View Related Profiles.

Coviello, Andrea
Zhang, Anqi
Ulloor, Jagadish
Murabito, Joanne
Lunetta, Kathryn
Bhasin, Shalender
Ramachandran, Vasan

PMID: 21752884; PMCID: PMC3167671; DOI: 10.1210/jc.2011-0050;

Bhasin S, Pencina M, Jasuja GK, Travison TG, Coviello A, Orwoll E, Wang PY, Nielson C, Wu F, Tajar A, Labrie F, Vesper H, Zhang A, Ulloor J, Singh R, D'Agostino R, Vasan RS. Reference ranges for testosterone in men generated using liquid chromatography tandem mass spectrometry in a community-based sample of healthy nonobese young men in the Framingham Heart Study and applied to three geographically distinct cohorts. J Clin Endocrinol Metab. 2011 Aug; 96(8):2430-9.View Related Profiles.

Coviello, Andrea
Zhang, Anqi
Jasuja, Guneet
Ulloor, Jagadish
Pencina, Michael
D'Agostino, Ralph
Bhasin, Shalender
Travison, Thomas
Ramachandran, Vasan

PMID: 21697255; PMCID: PMC3146796; DOI: 10.1210/jc.2010-3012;

Tan ZS, Beiser AS, Fox CS, Au R, Himali JJ, Debette S, Decarli C, Vasan RS, Wolf PA, Seshadri S. Association of metabolic dysregulation with volumetric brain magnetic resonance imaging and cognitive markers of subclinical brain aging in middle-aged adults: the Framingham Offspring Study. Diabetes Care. 2011 Aug; 34(8):1766-70.View Related Profiles.

Beiser, Alexa
Himali, Jayandra
Wolf, Philip
Au, Rhoda
Seshadri, Sudha
Ramachandran, Vasan

PMID: 21680719; PMCID: PMC3142014; DOI: 10.2337/dc11-0308;

Lam CS, Lyass A, Kraigher-Krainer E, Massaro JM, Lee DS, Ho JE, Levy D, Redfield MM, Pieske BM, Benjamin EJ, Vasan RS. Cardiac dysfunction and noncardiac dysfunction as precursors of heart failure with reduced and preserved ejection fraction in the community. Circulation. 2011 Jul 5; 124(1):24-30.View Related Profiles.

Benjamin, Emelia
Ho, Jennifer
Massaro, Joseph
Ramachandran, Vasan

PMID: 21670229; PMCID: PMC3257876; DOI: 10.1161/CIRCULATIONAHA.110.979203;

Zachariah JP, Pencina MJ, Lyass A, Kaur G, D'Agostino RB, Ordovas JM, Vasan RS. Circulating plasma cholesteryl ester transfer protein activity and blood pressure tracking in the community. J Hypertens. 2011 May; 29(5):863-8.View Related Profiles.

Jasuja, Guneet
Pencina, Michael
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 21430561; PMCID: PMC3204923; DOI: 10.1097/HJH.0b013e3283450223;

Kaess BM, Vasan RS. Heart failure: pentraxin 3—a marker of diastolic dysfunction and HF? Nat Rev Cardiol. 2011 May; 8(5):246-8.View Related Profiles.

Kaess, Bernhard
Ramachandran, Vasan

PMID: 21448138; PMCID: PMC3236065; DOI: 10.1038/nrcardio.2011.50;

Zhai G, Teumer A, Stolk L, Perry JR, Vandenput L, Coviello AD, Koster A, Bell JT, Bhasin S, Eriksson J, Eriksson A, Ernst F, Ferrucci L, Frayling TM, Glass D, Grundberg E, Haring R, Hedman AK, Hofman A, Kiel DP, Kroemer HK, Liu Y, Lunetta KL, Maggio M, Lorentzon M, Mangino M, Melzer D, Miljkovic I, Nica A, Penninx BW, Vasan RS, Rivadeneira F, Small KS, Soranzo N, Uitterlinden AG, Völzke H, Wilson SG, Xi L, Zhuang WV, Harris TB, Murabito JM, Ohlsson C, Murray A, de Jong FH, Spector TD, Wallaschofski H. Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms. PLoS Genet. 2011 Apr; 7(4):e1002025.View Related Profiles.

Coviello, Andrea
Murabito, Joanne
Lunetta, Kathryn
Bhasin, Shalender
Ramachandran, Vasan

PMID: 21533175; PMCID: PMC3077384; DOI: 10.1371/journal.pgen.1002025;

Shaw SY, Cheng S, Cupples LA, Larson MG, McCabe EL, Ngwa JS, Wang YA, Martin RP, Klein RJ, Hashmi B, Ajijola OA, Lau E, O'Donnell CJ, Vasan RS, Cohen KS, Wang TJ. Genetic and clinical correlates of early-outgrowth colony-forming units. Circ Cardiovasc Genet. 2011 Jun; 4(3):296-304.View Related Profiles.

O'Donnell, Christopher
Cupples, L
Larson, Martin
Ramachandran, Vasan

PMID: 21493818; PMCID: PMC3339257; DOI: 10.1161/CIRCGENETICS.110.958470;

Wormser D, Kaptoge S, Di Angelantonio E, Wood AM, Pennells L, Thompson A, Sarwar N, Kizer JR, Lawlor DA, Nordestgaard BG, Ridker P, Salomaa V, Stevens J, Woodward M, Sattar N, Collins R, Thompson SG, Whitlock G, Danesh J. Separate and combined associations of body-mass index and abdominal adiposity with cardiovascular disease: collaborative analysis of 58 prospective studies. Lancet. 2011 Mar 26; 377(9771):1085-95. PMID: 21397319; PMCID: PMC3145074; DOI: 10.1016/S0140-6736(11)60105-0;

Zhu X, Young JH, Fox E, Keating BJ, Franceschini N, Kang S, Tayo B, Adeyemo A, Sun YV, Li Y, Morrison A, Newton-Cheh C, Liu K, Ganesh SK, Kutlar A, Vasan RS, Dreisbach A, Wyatt S, Polak J, Palmas W, Musani S, Taylor H, Fabsitz R, Townsend RR, Dries D, Glessner J, Chiang CW, Mosley T, Kardia S, Curb D, Hirschhorn JN, Rotimi C, Reiner A, Eaton C, Rotter JI, Cooper RS, Redline S, Chakravarti A, Levy D. Combined admixture mapping and association analysis identifies a novel blood pressure genetic locus on 5p13: contributions from the CARe consortium. Hum Mol Genet. 2011 Jun 1; 20(11):2285-95.View Related Profiles.

Polak, Joseph
Ramachandran, Vasan

PMID: 21422096; PMCID: PMC3090198; DOI: 10.1093/hmg/ddr113;

Wang TJ, Larson MG, Vasan RS, Cheng S, Rhee EP, McCabe E, Lewis GD, Fox CS, Jacques PF, Fernandez C, O'Donnell CJ, Carr SA, Mootha VK, Florez JC, Souza A, Melander O, Clish CB, Gerszten RE. Metabolite profiles and the risk of developing diabetes. Nat Med. 2011 Apr; 17(4):448-53.View Related Profiles.

O'Donnell, Christopher
Larson, Martin
Ramachandran, Vasan

PMID: 21423183; PMCID: PMC3126616; DOI: 10.1038/nm.2307;

Rhee EP, Cheng S, Larson MG, Walford GA, Lewis GD, McCabe E, Yang E, Farrell L, Fox CS, O'Donnell CJ, Carr SA, Vasan RS, Florez JC, Clish CB, Wang TJ, Gerszten RE. Lipid profiling identifies a triacylglycerol signature of insulin resistance and improves diabetes prediction in humans. J Clin Invest. 2011 Apr; 121(4):1402-11.View Related Profiles.

O'Donnell, Christopher
Larson, Martin
Ramachandran, Vasan

PMID: 21403394; PMCID: PMC3069773; DOI: 10.1172/JCI44442;

Fox ER, Young JH, Li Y, Dreisbach AW, Keating BJ, Musani SK, Liu K, Morrison AC, Ganesh S, Kutlar A, Ramachandran VS, Polak JF, Fabsitz RR, Dries DL, Farlow DN, Redline S, Adeyemo A, Hirschorn JN, Sun YV, Wyatt SB, Penman AD, Palmas W, Rotter JI, Townsend RR, Doumatey AP, Tayo BO, Mosley TH, Lyon HN, Kang SJ, Rotimi CN, Cooper RS, Franceschini N, Curb JD, Martin LW, Eaton CB, Kardia SL, Taylor HA, Caulfield MJ, Ehret GB, Johnson T, Chakravarti A, Zhu X, Levy D. Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study. Hum Mol Genet. 2011 Jun 1; 20(11):2273-84.View Related Profiles.

Chen, Ming-Huei
Glazer, Nicole
Seshadri, Sudha
Ramachandran, Vasan

PMID: 21378095; PMCID: PMC3090190; DOI: 10.1093/hmg/ddr092;

Seshasai SR, Kaptoge S, Thompson A, Di Angelantonio E, Gao P, Sarwar N, Whincup PH, Mukamal KJ, Gillum RF, Holme I, Njølstad I, Fletcher A, Nilsson P, Lewington S, Collins R, Gudnason V, Thompson SG, Sattar N, Selvin E, Hu FB, Danesh J. Diabetes mellitus, fasting glucose, and risk of cause-specific death. N Engl J Med. 2011 Mar 3; 364(9):829-41. PMID: 21366474; PMCID: PMC4109980 ; DOI: 10.1056/NEJMoa1008862;

McManus DD, Shaikh AY, Abhishek F, Vasan RS. Atrial fibrillation and heart failure parallels: lessons for atrial fibrillation prevention. Crit Pathw Cardiol. 2011 Mar; 10(1):46-51. PMID: 21562376; PMCID: PMC3220939; DOI: 10.1097/HPC.0b013e31820e1a4b;

McManus DD, Lyass A, Ingelsson E, Massaro JM, Meigs JB, Aragam J, Benjamin EJ, Vasan RS. Relations of circulating resistin and adiponectin and cardiac structure and function: the Framingham Offspring Study. Obesity (Silver Spring). 2012 Sep; 20(9):1882-6.View Related Profiles.

Benjamin, Emelia
Aragam, Jayashri
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Ramachandran, Vasan

PMID: 21350435; PMCID: PMC3716016; DOI: 10.1038/oby.2011.32;

Wei GS, Coady SA, Goff DC, Brancati FL, Levy D, Selvin E, Vasan RS, Fox CS. Blood pressure and the risk of developing diabetes in african americans and whites: ARIC, CARDIA, and the framingham heart study. Diabetes Care. 2011 Apr; 34(4):873-9. PMID: 21346180; PMCID: PMC3064044; DOI: 10.2337/dc10-1786;

Wensley F, Gao P, Burgess S, Kaptoge S, Di Angelantonio E, Shah T, Engert JC, Clarke R, Davey-Smith G, Nordestgaard BG, Saleheen D, Samani NJ, Sandhu M, Anand S, Pepys MB, Smeeth L, Whittaker J, Casas JP, Thompson SG, Hingorani AD, Danesh J. Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data. BMJ. 2011; 342:d548. PMID: 21325005; PMCID: PMC3039696; DOI: 10.1136/bmj.d548;

Lieb W, Pencina MJ, Jacques PF, Wang TJ, Larson MG, Levy D, Kannel WB, Vasan RS. Higher aldosterone and lower N-terminal proatrial natriuretic peptide as biomarkers of salt sensitivity in the community. Eur J Cardiovasc Prev Rehabil. 2011 Aug; 18(4):664-73.View Related Profiles.

Larson, Martin
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PMID: 21450637; PMCID: PMC3179529; DOI: 10.1177/1741826710389406;

Robins SJ, Lyass A, Zachariah JP, Massaro JM, Vasan RS. Insulin resistance and the relationship of a dyslipidemia to coronary heart disease: the Framingham Heart Study. Arterioscler Thromb Vasc Biol. 2011 May; 31(5):1208-14.View Related Profiles.

Massaro, Joseph
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PMID: 21311041; PMCID: PMC3087170; DOI: 10.1161/ATVBAHA.110.219055;

Lettre G, Palmer CD, Young T, Ejebe KG, Allayee H, Benjamin EJ, Bennett F, Bowden DW, Chakravarti A, Dreisbach A, Farlow DN, Folsom AR, Fornage M, Forrester T, Fox E, Haiman CA, Hartiala J, Harris TB, Hazen SL, Heckbert SR, Henderson BE, Hirschhorn JN, Keating BJ, Kritchevsky SB, Larkin E, Li M, Rudock ME, McKenzie CA, Meigs JB, Meng YA, Mosley TH, Newman AB, Newton-Cheh CH, Paltoo DN, Papanicolaou GJ, Patterson N, Post WS, Psaty BM, Qasim AN, Qu L, Rader DJ, Redline S, Reilly MP, Reiner AP, Rich SS, Rotter JI, Liu Y, Shrader P, Siscovick DS, Tang WH, Taylor HA, Tracy RP, Vasan RS, Waters KM, Wilks R, Wilson JG, Fabsitz RR, Gabriel SB, Kathiresan S, Boerwinkle E. Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project. PLoS Genet. 2011; 7(2):e1001300.View Related Profiles.

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Ramachandran, Vasan

PMID: 21347282; PMCID: PMC3037413; DOI: 10.1371/journal.pgen.1001300;

Dehghan A, Dupuis J, Barbalic M, Bis JC, Eiriksdottir G, Lu C, Pellikka N, Wallaschofski H, Kettunen J, Henneman P, Baumert J, Strachan DP, Fuchsberger C, Vitart V, Wilson JF, Paré G, Naitza S, Rudock ME, Surakka I, de Geus EJ, Alizadeh BZ, Guralnik J, Shuldiner A, Tanaka T, Zee RY, Schnabel RB, Nambi V, Kavousi M, Ripatti S, Nauck M, Smith NL, Smith AV, Sundvall J, Scheet P, Liu Y, Ruokonen A, Rose LM, Larson MG, Hoogeveen RC, Freimer NB, Teumer A, Tracy RP, Launer LJ, Buring JE, Yamamoto JF, Folsom AR, Sijbrands EJ, Pankow J, Elliott P, Keaney JF, Sun W, Sarin AP, Fontes JD, Badola S, Astor BC, Hofman A, Pouta A, Werdan K, Greiser KH, Kuss O, Meyer zu Schwabedissen HE, Thiery J, Jamshidi Y, Nolte IM, Soranzo N, Spector TD, Völzke H, Parker AN, Aspelund T, Bates D, Young L, Tsui K, Siscovick DS, Guo X, Rotter JI, Uda M, Schlessinger D, Rudan I, Hicks AA, Penninx BW, Thorand B, Gieger C, Coresh J, Willemsen G, Harris TB, Uitterlinden AG, Järvelin MR, Rice K, Radke D, Salomaa V, Willems van Dijk K, Boerwinkle E, Vasan RS, Ferrucci L, Gibson QD, Bandinelli S, Snieder H, Boomsma DI, Xiao X, Campbell H, Hayward C, Pramstaller PP, van Duijn CM, Peltonen L, Psaty BM, Gudnason V, Ridker PM, Homuth G, Koenig W, Ballantyne CM, Witteman JC, Benjamin EJ, Perola M, Chasman DI. Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels. Circulation. 2011 Feb 22; 123(7):731-8.View Related Profiles.

Benjamin, Emelia
Dupuis, Josee
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Zee, Robert
Ramachandran, Vasan

PMID: 21300955; PMCID: PMC3147232; DOI: 10.1161/CIRCULATIONAHA.110.948570;

Hamburg NM, Palmisano J, Larson MG, Sullivan LM, Lehman BT, Vasan RS, Levy D, Mitchell GF, Vita JA, Benjamin EJ. Relation of brachial and digital measures of vascular function in the community: the Framingham heart study. Hypertension. 2011 Mar; 57(3):390-6.View Related Profiles.

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Vita, Joseph
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PMID: 21263120; PMCID: PMC3049726; DOI: 10.1161/HYPERTENSIONAHA.110.160812;

Hansson J, Vasan RS, Ärnlöv J, Ingelsson E, Lind L, Larsson A, Michaëlsson K, Sundström J. Biomarkers of extracellular matrix metabolism (MMP-9 and TIMP-1) and risk of stroke, myocardial infarction, and cause-specific mortality: cohort study. PLoS One. 2011; 6(1):e16185. PMID: 21283828; PMCID: PMC3023803; DOI: 10.1371/journal.pone.0016185;

Kaess BM, Vasan RS. Statins are not associated with a decrease in all cause mortality in a high-risk primary prevention setting. Evid Based Med. 2011 Feb; 16(1):8-9.View Related Profiles.

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Ramachandran, Vasan

PMID: 21224283; DOI: 10.1136/ebm1125;

Kaplan RC, Petersen AK, Chen MH, Teumer A, Glazer NL, Döring A, Lam CS, Friedrich N, Newman A, Müller M, Yang Q, Homuth G, Cappola A, Klopp N, Smith H, Ernst F, Psaty BM, Wichmann HE, Sawyer DB, Biffar R, Rotter JI, Gieger C, Sullivan LS, Völzke H, Rice K, Spyroglou A, Kroemer HK, Ida Chen YD, Manolopoulou J, Nauck M, Strickler HD, Goodarzi MO, Reincke M, Pollak MN, Bidlingmaier M, Vasan RS, Wallaschofski H. A genome-wide association study identifies novel loci associated with circulating IGF-I and IGFBP-3. Hum Mol Genet. 2011 Mar 15; 20(6):1241-51.View Related Profiles.

Chen, Ming-Huei
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Yang, Qiong
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PMID: 21216879; PMCID: PMC3043664; DOI: 10.1093/hmg/ddq560;

Foster MC, Hwang SJ, Massaro JM, Hoffmann U, DeBoer IH, Robins SJ, Vasan RS, Fox CS. Association of subcutaneous and visceral adiposity with albuminuria: the Framingham Heart Study. Obesity (Silver Spring). 2011 Jun; 19(6):1284-9.View Related Profiles.

Massaro, Joseph
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PMID: 21183930; PMCID: PMC3096746; DOI: 10.1038/oby.2010.308;

Thanassoulis G, Vasan RS. Genetic cardiovascular risk prediction: will we get there? Circulation. 2010 Nov 30; 122(22):2323-34. PMID: 21147729; PMCID: PMC3075800; DOI: 10.1161/CIRCULATIONAHA.109.909309;

Shen J, Johnson VM, Sullivan LM, Jacques PF, Magnani JW, Lubitz SA, Pandey S, Levy D, Vasan RS, Quatromoni PA, Junyent M, Ordovas JM, Benjamin EJ. Dietary factors and incident atrial fibrillation: the Framingham Heart Study. Am J Clin Nutr. 2011 Feb; 93(2):261-6.View Related Profiles.

Benjamin, Emelia
Magnani, Jared
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PMID: 21106919; PMCID: PMC3021424; DOI: 10.3945/ajcn.110.001305;

Schnabel RB, Aspelund T, Li G, Sullivan LM, Suchy-Dicey A, Harris TB, Pencina MJ, D'Agostino RB, Levy D, Kannel WB, Wang TJ, Kronmal RA, Wolf PA, Burke GL, Launer LJ, Vasan RS, Psaty BM, Benjamin EJ, Gudnason V, Heckbert SR. Validation of an atrial fibrillation risk algorithm in whites and African Americans. Arch Intern Med. 2010 Nov 22; 170(21):1909-17.View Related Profiles.

Benjamin, Emelia
Sullivan, Lisa
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PMID: 21098350; PMCID: PMC3021784; DOI: 10.1001/archinternmed.2010.434;

Lubitz SA, Yin X, Fontes JD, Magnani JW, Rienstra M, Pai M, Villalon ML, Vasan RS, Pencina MJ, Levy D, Larson MG, Ellinor PT, Benjamin EJ. Association between familial atrial fibrillation and risk of new-onset atrial fibrillation. JAMA. 2010 Nov 24; 304(20):2263-9.View Related Profiles.

Benjamin, Emelia
Magnani, Jared
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Yin, Xiaoyan

PMID: 21076174; PMCID: PMC3073054; DOI: 10.1001/jama.2010.1690;

Lee DS, Gona P, Albano I, Larson MG, Benjamin EJ, Levy D, Kannel WB, Vasan RS. A systematic assessment of causes of death after heart failure onset in the community: impact of age at death, time period, and left ventricular systolic dysfunction. Circ Heart Fail. 2011 Jan; 4(1):36-43.View Related Profiles.

Benjamin, Emelia
Larson, Martin
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PMID: 21071547; PMCID: PMC3243964; DOI: 10.1161/CIRCHEARTFAILURE.110.957480;

Fox CS, Gona P, Larson MG, Selhub J, Tofler G, Hwang SJ, Meigs JB, Levy D, Wang TJ, Jacques PF, Benjamin EJ, Vasan RS. A multi-marker approach to predict incident CKD and microalbuminuria. J Am Soc Nephrol. 2010 Dec; 21(12):2143-9.View Related Profiles.

Benjamin, Emelia
Larson, Martin
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PMID: 20966127; PMCID: PMC3014027; DOI: 10.1681/ASN.2010010085;

Velagaleti RS, Gona P, Larson MG, Wang TJ, Levy D, Benjamin EJ, Selhub J, Jacques PF, Meigs JB, Tofler GH, Vasan RS. Multimarker approach for the prediction of heart failure incidence in the community. Circulation. 2010 Oct 26; 122(17):1700-6.View Related Profiles.

Benjamin, Emelia
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PMID: 20937976; PMCID: PMC2993157; DOI: 10.1161/CIRCULATIONAHA.109.929661;

Khan AM, Sullivan L, McCabe E, Levy D, Vasan RS, Wang TJ. Lack of association between serum magnesium and the risks of hypertension and cardiovascular disease. Am Heart J. 2010 Oct; 160(4):715-20.View Related Profiles.

Sullivan, Lisa
Ramachandran, Vasan

PMID: 20934566; PMCID: PMC2953800; DOI: 10.1016/j.ahj.2010.06.036;

Lam CS, Liu X, Yang Q, Larson MG, Pencina MJ, Aragam J, Redfield MM, Benjamin EJ, Vasan RS. Familial aggregation of left ventricular geometry and association with parental heart failure: the Framingham Heart Study. Circ Cardiovasc Genet. 2010 Dec; 3(6):492-8.View Related Profiles.

Benjamin, Emelia
Aragam, Jayashri
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PMID: 20884845; PMCID: PMC3785074; DOI: 10.1161/CIRCGENETICS.110.941088;

Cheng S, Lyass A, Massaro JM, O'Connor GT, Keaney JF, Vasan RS. Exhaled carbon monoxide and risk of metabolic syndrome and cardiovascular disease in the community. Circulation. 2010 Oct 12; 122(15):1470-7.View Related Profiles.

O'Connor, George
Massaro, Joseph
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PMID: 20876437; PMCID: PMC2975571; DOI: 10.1161/CIRCULATIONAHA.110.941013;

Mitchell GF, Wang N, Palmisano JN, Larson MG, Hamburg NM, Vita JA, Levy D, Benjamin EJ, Vasan RS. Hemodynamic correlates of blood pressure across the adult age spectrum: noninvasive evaluation in the Framingham Heart Study. Circulation. 2010 Oct 5; 122(14):1379-86.View Related Profiles.

Benjamin, Emelia
Vita, Joseph
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PMID: 20855656; PMCID: PMC2981604; DOI: 10.1161/CIRCULATIONAHA.109.914507;

Schnabel RB, Schulz A, Messow CM, Lubos E, Wild PS, Zeller T, Sinning CR, Rupprecht HJ, Bickel C, Peetz D, Cambien F, Kempf T, Wollert KC, Benjamin EJ, Lackner KJ, Münzel TF, Tiret L, Vasan RS, Blankenberg S. Multiple marker approach to risk stratification in patients with stable coronary artery disease. Eur Heart J. 2010 Dec; 31(24):3024-31.View Related Profiles.

Benjamin, Emelia
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PMID: 20852293; DOI: 10.1093/eurheartj/ehq322;

Cheng S, Cohen KS, Shaw SY, Larson MG, Hwang SJ, McCabe EL, Martin RP, Klein RJ, Hashmi B, Hoffmann U, Fox CS, Vasan RS, O'Donnell CJ, Wang TJ. Association of colony-forming units with coronary artery and abdominal aortic calcification. Circulation. 2010 Sep 21; 122(12):1176-82.View Related Profiles.

O'Donnell, Christopher
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PMID: 20823386; PMCID: PMC3050056; DOI: 10.1161/CIRCULATIONAHA.109.931279;

Velagaleti RS, Gona P, Sundström J, Larson MG, Siwik D, Colucci WS, Benjamin EJ, Vasan RS. Relations of biomarkers of extracellular matrix remodeling to incident cardiovascular events and mortality. Arterioscler Thromb Vasc Biol. 2010 Nov; 30(11):2283-8.View Related Profiles.

Siwik, Deborah
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Colucci, Wilson

PMID: 20798380; PMCID: PMC2959140; DOI: 10.1161/ATVBAHA.110.208462;

Pencina MJ, D'Agostino RB, Vasan RS. Statistical methods for assessment of added usefulness of new biomarkers. Clin Chem Lab Med. 2010 Dec; 48(12):1703-11.View Related Profiles.

Pencina, Michael
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PMID: 20716010; PMCID: PMC3155999; DOI: 10.1515/CCLM.2010.340;

Lam CS, Xanthakis V, Sullivan LM, Lieb W, Aragam J, Redfield MM, Mitchell GF, Benjamin EJ, Vasan RS. Aortic root remodeling over the adult life course: longitudinal data from the Framingham Heart Study. Circulation. 2010 Aug 31; 122(9):884-90.View Related Profiles.

Benjamin, Emelia
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PMID: 20713896; PMCID: PMC2956587; DOI: 10.1161/CIRCULATIONAHA.110.937839;

Lam CS, Donal E, Kraigher-Krainer E, Vasan RS. Epidemiology and clinical course of heart failure with preserved ejection fraction. Eur J Heart Fail. 2011 Jan; 13(1):18-28. PMID: 20685685; PMCID: PMC3003453; DOI: 10.1093/eurjhf/hfq121;

Upadhyay A, Larson MG, Guo CY, Vasan RS, Lipinska I, O'Donnell CJ, Kathiresan S, Meigs JB, Keaney JF, Rong J, Benjamin EJ, Fox CS. Inflammation, kidney function and albuminuria in the Framingham Offspring cohort. Nephrol Dial Transplant. 2011 Mar; 26(3):920-6.View Related Profiles.

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PMID: 20682604; PMCID: PMC3108344; DOI: 10.1093/ndt/gfq471;

Dhingra R, Gona P, Benjamin EJ, Wang TJ, Aragam J, D'Agostino RB, Kannel WB, Vasan RS. Relations of serum phosphorus levels to echocardiographic left ventricular mass and incidence of heart failure in the community. Eur J Heart Fail. 2010 Aug; 12(8):812-8.View Related Profiles.

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PMID: 20675668; PMCID: PMC2913049; DOI: 10.1093/eurjhf/hfq106;

Cheng S, Xanthakis V, Sullivan LM, Lieb W, Massaro J, Aragam J, Benjamin EJ, Vasan RS. Correlates of echocardiographic indices of cardiac remodeling over the adult life course: longitudinal observations from the Framingham Heart Study. Circulation. 2010 Aug 10; 122(6):570-8.View Related Profiles.

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PMID: 20660804; PMCID: PMC2942081; DOI: 10.1161/CIRCULATIONAHA.110.937821;

Cheng S, Larson MG, Keyes MJ, McCabe EL, Newton-Cheh C, Levy D, Benjamin EJ, Vasan RS, Wang TJ. Relation of QRS width in healthy persons to risk of future permanent pacemaker implantation. Am J Cardiol. 2010 Sep 1; 106(5):668-72.View Related Profiles.

Benjamin, Emelia
Larson, Martin
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PMID: 20723643; PMCID: PMC3012354; DOI: 10.1016/j.amjcard.2010.04.021;

Wild PS, Sinning CR, Roth A, Wilde S, Schnabel RB, Lubos E, Zeller T, Keller T, Lackner KJ, Blettner M, Vasan RS, Münzel T, Blankenberg S. Distribution and categorization of left ventricular measurements in the general population: results from the population-based Gutenberg Heart Study. Circ Cardiovasc Imaging. 2010 Sep; 3(5):604-13. PMID: 20643817; DOI: 10.1161/CIRCIMAGING.109.911933;

Freedman JE, Larson MG, Tanriverdi K, O'Donnell CJ, Morin K, Hakanson AS, Vasan RS, Johnson AD, Iafrati MD, Benjamin EJ. Relation of platelet and leukocyte inflammatory transcripts to body mass index in the Framingham heart study. Circulation. 2010 Jul 13; 122(2):119-29.View Related Profiles.

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PMID: 20606121; PMCID: PMC2910759; DOI: 10.1161/CIRCULATIONAHA.109.928192;

Lam CS, Vasan RS. Heart failure risk: lessons from the family. Congest Heart Fail. 2010 Jul-Aug; 16(4):139-40. PMID: 20662864; PMCID: PMC3007119; DOI: 10.1111/j.1751-7133.2010.00155.x;

Dietrich M, Jacques PF, Polak JF, Keyes MJ, Pencina MJ, Evans JC, Wolf PA, Selhub J, Vasan RS, D'Agostino RB. Segment-specific association between plasma homocysteine level and carotid artery intima-media thickness in the Framingham Offspring Study. J Stroke Cerebrovasc Dis. 2011 Mar-Apr; 20(2):155-61.View Related Profiles.

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PMID: 20580253; PMCID: PMC3011043; DOI: 10.1016/j.jstrokecerebrovasdis.2009.10.012;

Sarwar N, Gao P, Seshasai SR, Gobin R, Kaptoge S, Di Angelantonio E, Ingelsson E, Lawlor DA, Selvin E, Stampfer M, Stehouwer CD, Lewington S, Pennells L, Thompson A, Sattar N, White IR, Ray KK, Danesh J. Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies. Lancet. 2010 Jun 26; 375(9733):2215-22. PMID: 20609967; PMCID: PMC2904878; DOI: 10.1016/S0140-6736(10)60484-9;

Thanassoulis G, Massaro JM, O'Donnell CJ, Hoffmann U, Levy D, Ellinor PT, Wang TJ, Schnabel RB, Vasan RS, Fox CS, Benjamin EJ. Pericardial fat is associated with prevalent atrial fibrillation: the Framingham Heart Study. Circ Arrhythm Electrophysiol. 2010 Aug; 3(4):345-50.View Related Profiles.

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PMID: 20558845; PMCID: PMC2953855; DOI: 10.1161/CIRCEP.109.912055;

Dhingra R, Gona P, Wang TJ, Fox CS, D'Agostino RB, Vasan RS. Serum gamma-glutamyl transferase and risk of heart failure in the community. Arterioscler Thromb Vasc Biol. 2010 Sep; 30(9):1855-60.View Related Profiles.

D'Agostino, Ralph
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PMID: 20539015; PMCID: PMC2924453; DOI: 10.1161/ATVBAHA.110.207340;

Wang TJ, Zhang F, Richards JB, Kestenbaum B, van Meurs JB, Berry D, Kiel DP, Streeten EA, Ohlsson C, Koller DL, Peltonen L, Cooper JD, O'Reilly PF, Houston DK, Glazer NL, Vandenput L, Peacock M, Shi J, Rivadeneira F, McCarthy MI, Anneli P, de Boer IH, Mangino M, Kato B, Smyth DJ, Booth SL, Jacques PF, Burke GL, Goodarzi M, Cheung CL, Wolf M, Rice K, Goltzman D, Hidiroglou N, Ladouceur M, Wareham NJ, Hocking LJ, Hart D, Arden NK, Cooper C, Malik S, Fraser WD, Hartikainen AL, Zhai G, Macdonald HM, Forouhi NG, Loos RJ, Reid DM, Hakim A, Dennison E, Liu Y, Power C, Stevens HE, Jaana L, Vasan RS, Soranzo N, Bojunga J, Psaty BM, Lorentzon M, Foroud T, Harris TB, Hofman A, Jansson JO, Cauley JA, Uitterlinden AG, Gibson Q, Järvelin MR, Karasik D, Siscovick DS, Econs MJ, Kritchevsky SB, Florez JC, Todd JA, Dupuis J, Hyppönen E, Spector TD. Common genetic determinants of vitamin D insufficiency: a genome-wide association study. Lancet. 2010 Jul 17; 376(9736):180-8.View Related Profiles.

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PMID: 20541252; PMCID: PMC3086761; DOI: 10.1016/S0140-6736(10)60588-0;

Thanassoulis G, Massaro JM, Hoffmann U, Mahabadi AA, Vasan RS, O'Donnell CJ, Fox CS. Prevalence, distribution, and risk factor correlates of high pericardial and intrathoracic fat depots in the Framingham heart study. Circ Cardiovasc Imaging. 2010 Sep; 3(5):559-66.View Related Profiles.

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PMID: 20525769; PMCID: PMC3063852; DOI: 10.1161/CIRCIMAGING.110.956706;

Thanassoulis G, Massaro JM, Cury R, Manders E, Benjamin EJ, Vasan RS, Cupple LA, Hoffmann U, O'Donnell CJ, Kathiresan S. Associations of long-term and early adult atherosclerosis risk factors with aortic and mitral valve calcium. J Am Coll Cardiol. 2010 Jun 1; 55(22):2491-8.View Related Profiles.

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PMID: 20510217; PMCID: PMC3042249; DOI: 10.1016/j.jacc.2010.03.019;

Speliotes EK, Massaro JM, Hoffmann U, Vasan RS, Meigs JB, Sahani DV, Hirschhorn JN, O'Donnell CJ, Fox CS. Fatty liver is associated with dyslipidemia and dysglycemia independent of visceral fat: the Framingham Heart Study. Hepatology. 2010 Jun; 51(6):1979-87.View Related Profiles.

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PMID: 20336705; PMCID: PMC3023160; DOI: 10.1002/hep.23593;

Lewis GD, Farrell L, Wood MJ, Martinovic M, Arany Z, Rowe GC, Souza A, Cheng S, McCabe EL, Yang E, Shi X, Deo R, Roth FP, Asnani A, Rhee EP, Systrom DM, Semigran MJ, Vasan RS, Carr SA, Wang TJ, Sabatine MS, Clish CB, Gerszten RE. Metabolic signatures of exercise in human plasma. Sci Transl Med. 2010 May 26; 2(33):33ra37. PMID: 20505214; PMCID: PMC3010398; DOI: 10.1126/scitranslmed.3001006;

Preis SR, Massaro JM, Hoffmann U, D'Agostino RB, Levy D, Robins SJ, Meigs JB, Vasan RS, O'Donnell CJ, Fox CS. Neck circumference as a novel measure of cardiometabolic risk: the Framingham Heart study. J Clin Endocrinol Metab. 2010 Aug; 95(8):3701-10.View Related Profiles.

O'Donnell, Christopher
Massaro, Joseph
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PMID: 20484490; PMCID: PMC2913042; DOI: 10.1210/jc.2009-1779;

Sarwar N, Sandhu MS, Ricketts SL, Butterworth AS, Di Angelantonio E, Boekholdt SM, Ouwehand W, Watkins H, Samani NJ, Saleheen D, Lawlor D, Reilly MP, Hingorani AD, Talmud PJ, Danesh J. Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies. Lancet. 2010 May 8; 375(9726):1634-9.View Related Profiles.

Ruiz-Narvaez, Edward
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PMID: 20452521; PMCID: PMC2867029; DOI: 10.1016/S0140-6736(10)60545-4;

Lieb W, Gona P, Larson MG, Massaro JM, Lipinska I, Keaney JF, Rong J, Corey D, Hoffmann U, Fox CS, Vasan RS, Benjamin EJ, O'Donnell CJ, Kathiresan S. Biomarkers of the osteoprotegerin pathway: clinical correlates, subclinical disease, incident cardiovascular disease, and mortality. Arterioscler Thromb Vasc Biol. 2010 Sep; 30(9):1849-54.View Related Profiles.

O'Donnell, Christopher
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PMID: 20448212; PMCID: PMC3039214; DOI: 10.1161/ATVBAHA.109.199661;

Smith NL, Felix JF, Morrison AC, Demissie S, Glazer NL, Loehr LR, Cupples LA, Dehghan A, Lumley T, Rosamond WD, Lieb W, Rivadeneira F, Bis JC, Folsom AR, Benjamin E, Aulchenko YS, Haritunians T, Couper D, Murabito J, Wang YA, Stricker BH, Gottdiener JS, Chang PP, Wang TJ, Rice KM, Hofman A, Heckbert SR, Fox ER, O'Donnell CJ, Uitterlinden AG, Rotter JI, Willerson JT, Levy D, van Duijn CM, Psaty BM, Witteman JC, Boerwinkle E, Vasan RS. Association of genome-wide variation with the risk of incident heart failure in adults of European and African ancestry: a prospective meta-analysis from the cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium. Circ Cardiovasc Genet. 2010 Jun; 3(3):256-66.View Related Profiles.

O'Donnell, Christopher
Benjamin, Emelia
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PMID: 20445134; PMCID: PMC3025695; DOI: 10.1161/CIRCGENETICS.109.895763;

Thompson S, Kaptoge S, White I, Wood A, Perry P, Danesh J. Statistical methods for the time-to-event analysis of individual participant data from multiple epidemiological studies. Int J Epidemiol. 2010 Oct; 39(5):1345-59. PMID: 20439481; PMCID: PMC2972437; DOI: 10.1093/ije/dyq063;

Levy D, Splansky GL, Strand NK, Atwood LD, Benjamin EJ, Blease S, Cupples LA, D'Agostino RB, Fox CS, Kelly-Hayes M, Koski G, Larson MG, Mutalik KM, Oberacker E, O'Donnell CJ, Sutherland P, Valentino M, Vasan RS, Wolf PA, Murabito JM. Consent for genetic research in the Framingham Heart Study. Am J Med Genet A. 2010 May; 152A(5):1250-6.View Related Profiles.

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PMID: 20425830; PMCID: PMC2923558; DOI: 10.1002/ajmg.a.33377;

Thompson A, Gao P, Orfei L, Watson S, Di Angelantonio E, Kaptoge S, Ballantyne C, Cannon CP, Criqui M, Cushman M, Hofman A, Packard C, Thompson SG, Collins R, Danesh J. Lipoprotein-associated phospholipase A(2) and risk of coronary disease, stroke, and mortality: collaborative analysis of 32 prospective studies. Lancet. 2010 May 1; 375(9725):1536-44. PMID: 20435228; PMCID: PMC2864403; DOI: 10.1016/S0140-6736(10)60319-4;

Kalogeropoulos A, Psaty BM, Vasan RS, Georgiopoulou V, Smith AL, Smith NL, Kritchevsky SB, Wilson PW, Newman AB, Harris TB, Butler J. Validation of the health ABC heart failure model for incident heart failure risk prediction: the Cardiovascular Health Study. Circ Heart Fail. 2010 Jul; 3(4):495-502. PMID: 20427700; PMCID: PMC3285297; DOI: 10.1161/CIRCHEARTFAILURE.109.904300;

Levy D, Neuhausen SL, Hunt SC, Kimura M, Hwang SJ, Chen W, Bis JC, Fitzpatrick AL, Smith E, Johnson AD, Gardner JP, Srinivasan SR, Schork N, Rotter JI, Herbig U, Psaty BM, Sastrasinh M, Murray SS, Vasan RS, Province MA, Glazer NL, Lu X, Cao X, Kronmal R, Mangino M, Soranzo N, Spector TD, Berenson GS, Aviv A. Genome-wide association identifies OBFC1 as a locus involved in human leukocyte telomere biology. Proc Natl Acad Sci U S A. 2010 May 18; 107(20):9293-8.View Related Profiles.

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PMID: 20421499; PMCID: PMC2889047; DOI: 10.1073/pnas.0911494107;

Genome-wide meta-analyses identify multiple loci associated with smoking behavior. Nat Genet. 2010 May; 42(5):441-7.View Related Profiles.

Benjamin, Emelia
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PMID: 20418890; PMCID: PMC2914600; DOI: 10.1038/ng.571;

Vasan RS. The importance and urgency of preventing CVD. Circulation. 2010 Apr 20; 121(15):1685. PMID: 20408253

Musunuru K, Lettre G, Young T, Farlow DN, Pirruccello JP, Ejebe KG, Keating BJ, Yang Q, Chen MH, Lapchyk N, Crenshaw A, Ziaugra L, Rachupka A, Benjamin EJ, Cupples LA, Fornage M, Fox ER, Heckbert SR, Hirschhorn JN, Newton-Cheh C, Nizzari MM, Paltoo DN, Papanicolaou GJ, Patel SR, Psaty BM, Rader DJ, Redline S, Rich SS, Rotter JI, Taylor HA, Tracy RP, Vasan RS, Wilson JG, Kathiresan S, Fabsitz RR, Boerwinkle E, Gabriel SB. Candidate gene association resource (CARe): design, methods, and proof of concept. Circ Cardiovasc Genet. 2010 Jun; 3(3):267-75.View Related Profiles.

Benjamin, Emelia
Cupples, L
Chen, Ming-Huei
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PMID: 20400780; PMCID: PMC3048024; DOI: 10.1161/CIRCGENETICS.109.882696;

Morrison AC, Felix JF, Cupples LA, Glazer NL, Loehr LR, Dehghan A, Demissie S, Bis JC, Rosamond WD, Aulchenko YS, Wang YA, Haritunians T, Folsom AR, Rivadeneira F, Benjamin EJ, Lumley T, Couper D, Stricker BH, O'Donnell CJ, Rice KM, Chang PP, Hofman A, Levy D, Rotter JI, Fox ER, Uitterlinden AG, Wang TJ, Psaty BM, Willerson JT, van Duijn CM, Boerwinkle E, Witteman JC, Vasan RS, Smith NL. Genomic variation associated with mortality among adults of European and African ancestry with heart failure: the cohorts for heart and aging research in genomic epidemiology consortium. Circ Cardiovasc Genet. 2010 Jun; 3(3):248-55.View Related Profiles.

O'Donnell, Christopher
Benjamin, Emelia
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PMID: 20400778; PMCID: PMC3033765; DOI: 10.1161/CIRCGENETICS.109.895995;

Krasnoff JB, Basaria S, Pencina MJ, Jasuja GK, Vasan RS, Ulloor J, Zhang A, Coviello A, Kelly-Hayes M, D'Agostino RB, Wolf PA, Bhasin S, Murabito JM. Free testosterone levels are associated with mobility limitation and physical performance in community-dwelling men: the Framingham Offspring Study. J Clin Endocrinol Metab. 2010 Jun; 95(6):2790-9.View Related Profiles.

Coviello, Andrea
Zhang, Anqi
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Bhasin, Shalender
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PMID: 20382680; PMCID: PMC2902069; DOI: 10.1210/jc.2009-2680;

Lam CS, Chen MH, Lacey SM, Yang Q, Sullivan LM, Xanthakis V, Safa R, Smith HM, Peng X, Sawyer DB, Vasan RS. Circulating insulin-like growth factor-1 and its binding protein-3: metabolic and genetic correlates in the community. Arterioscler Thromb Vasc Biol. 2010 Jul; 30(7):1479-84.View Related Profiles.

Sullivan, Lisa
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PMID: 20378848; PMCID: PMC2891230; DOI: 10.1161/ATVBAHA.110.203943;

Pearce EN, Yang Q, Benjamin EJ, Aragam J, Vasan RS. Thyroid function and left ventricular structure and function in the Framingham Heart Study. Thyroid. 2010 Apr; 20(4):369-73.View Related Profiles.

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PMID: 20210671; PMCID: PMC2867586; DOI: 10.1089/thy.2009.0272;

Lieb W, Zachariah JP, Xanthakis V, Safa R, Chen MH, Sullivan LM, Larson MG, Smith HM, Yang Q, Mitchell GF, Vita JA, Sawyer DB, Vasan RS. Clinical and genetic correlates of circulating angiopoietin-2 and soluble Tie-2 in the community. Circ Cardiovasc Genet. 2010 Jun; 3(3):300-6.View Related Profiles.

Vita, Joseph
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PMID: 20348331; PMCID: PMC2892960; DOI: 10.1161/CIRCGENETICS.109.914556;

Preis SR, Massaro JM, Robins SJ, Hoffmann U, Vasan RS, Irlbeck T, Meigs JB, Sutherland P, D'Agostino RB, O'Donnell CJ, Fox CS. Abdominal subcutaneous and visceral adipose tissue and insulin resistance in the Framingham heart study. Obesity (Silver Spring). 2010 Nov; 18(11):2191-8.View Related Profiles.

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PMID: 20339361; PMCID: PMC3033570; DOI: 10.1038/oby.2010.59;

Anderssohn M, Schwedhelm E, Lüneburg N, Vasan RS, Böger RH. Asymmetric dimethylarginine as a mediator of vascular dysfunction and a marker of cardiovascular disease and mortality: an intriguing interaction with diabetes mellitus. Diab Vasc Dis Res. 2010 Apr; 7(2):105-18. PMID: 20382774; DOI: 10.1177/1479164110366053;

Velagaleti RS, Pencina MJ, Vasan RS, Benjamin EJ, Massaro JM, Pencina K, Levy D. Cross-sectional relations of lipid concentrations to left ventricular structural attributes. Am J Cardiol. 2010 May 1; 105(9):1297-9.View Related Profiles.

Benjamin, Emelia
Massaro, Joseph
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PMID: 20403482; PMCID: PMC2866083; DOI: 10.1016/j.amjcard.2009.12.050;

Deo RC, Hunter L, Lewis GD, Pare G, Vasan RS, Chasman D, Wang TJ, Gerszten RE, Roth FP. Interpreting metabolomic profiles using unbiased pathway models. PLoS Comput Biol. 2010 Feb; 6(2):e1000692. PMID: 20195502; PMCID: PMC2829050; DOI: 10.1371/journal.pcbi.1000692;

Ellinor PT, Lunetta KL, Glazer NL, Pfeufer A, Alonso A, Chung MK, Sinner MF, de Bakker PI, Mueller M, Lubitz SA, Fox E, Darbar D, Smith NL, Smith JD, Schnabel RB, Soliman EZ, Rice KM, Van Wagoner DR, Beckmann BM, van Noord C, Wang K, Ehret GB, Rotter JI, Hazen SL, Steinbeck G, Smith AV, Launer LJ, Harris TB, Makino S, Nelis M, Milan DJ, Perz S, Esko T, Köttgen A, Moebus S, Newton-Cheh C, Li M, Möhlenkamp S, Wang TJ, Kao WH, Vasan RS, Nöthen MM, MacRae CA, Stricker BH, Hofman A, Uitterlinden AG, Levy D, Boerwinkle E, Metspalu A, Topol EJ, Chakravarti A, Gudnason V, Psaty BM, Roden DM, Meitinger T, Wichmann HE, Witteman JC, Barnard J, Arking DE, Benjamin EJ, Heckbert SR, Kääb S. Common variants in KCNN3 are associated with lone atrial fibrillation. Nat Genet. 2010 Mar; 42(3):240-4.View Related Profiles.

Benjamin, Emelia
Lunetta, Kathryn
Glazer, Nicole
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PMID: 20173747; PMCID: PMC2871387; DOI: 10.1038/ng.537;

Barbalic M, Dupuis J, Dehghan A, Bis JC, Hoogeveen RC, Schnabel RB, Nambi V, Bretler M, Smith NL, Peters A, Lu C, Tracy RP, Aleksic N, Heeriga J, Keaney JF, Rice K, Lip GY, Vasan RS, Glazer NL, Larson MG, Uitterlinden AG, Yamamoto J, Durda P, Haritunians T, Psaty BM, Boerwinkle E, Hofman A, Koenig W, Jenny NS, Witteman JC, Ballantyne C, Benjamin EJ. Large-scale genomic studies reveal central role of ABO in sP-selectin and sICAM-1 levels. Hum Mol Genet. 2010 May 1; 19(9):1863-72.View Related Profiles.

Benjamin, Emelia
Dupuis, Josee
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PMID: 20167578; PMCID: PMC2850624; DOI: 10.1093/hmg/ddq061;

McManus DD, Xanthakis V, Sullivan LM, Zachariah J, Aragam J, Larson MG, Benjamin EJ, Vasan RS. Longitudinal tracking of left atrial diameter over the adult life course: Clinical correlates in the community. Circulation. 2010 Feb 9; 121(5):667-74.View Related Profiles.

Benjamin, Emelia
Aragam, Jayashri
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PMID: 20100973; PMCID: PMC2823068; DOI: 10.1161/CIRCULATIONAHA.109.885806;

Mitchell GF, Hwang SJ, Vasan RS, Larson MG, Pencina MJ, Hamburg NM, Vita JA, Levy D, Benjamin EJ. Arterial stiffness and cardiovascular events: the Framingham Heart Study. Circulation. 2010 Feb 2; 121(4):505-11.View Related Profiles.

Benjamin, Emelia
Vita, Joseph
Larson, Martin
Pencina, Michael
Hamburg, Naomi
Hwang, Shih-Jen
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PMID: 20083680; PMCID: PMC2836717; DOI: 10.1161/CIRCULATIONAHA.109.886655;

Pfeufer A, van Noord C, Marciante KD, Arking DE, Larson MG, Smith AV, Tarasov KV, Müller M, Sotoodehnia N, Sinner MF, Verwoert GC, Li M, Kao WH, Köttgen A, Coresh J, Bis JC, Psaty BM, Rice K, Rotter JI, Rivadeneira F, Hofman A, Kors JA, Stricker BH, Uitterlinden AG, van Duijn CM, Beckmann BM, Sauter W, Gieger C, Lubitz SA, Newton-Cheh C, Wang TJ, Magnani JW, Schnabel RB, Chung MK, Barnard J, Smith JD, Van Wagoner DR, Vasan RS, Aspelund T, Eiriksdottir G, Harris TB, Launer LJ, Najjar SS, Lakatta E, Schlessinger D, Uda M, Abecasis GR, Müller-Myhsok B, Ehret GB, Boerwinkle E, Chakravarti A, Soliman EZ, Lunetta KL, Perz S, Wichmann HE, Meitinger T, Levy D, Gudnason V, Ellinor PT, Sanna S, Kääb S, Witteman JC, Alonso A, Benjamin EJ, Heckbert SR. Genome-wide association study of PR interval. Nat Genet. 2010 Feb; 42(2):153-9.View Related Profiles.

Benjamin, Emelia
Magnani, Jared
Lunetta, Kathryn
Larson, Martin
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PMID: 20062060; PMCID: PMC2850197; DOI: 10.1038/ng.517;

Schnabel RB, Larson MG, Yamamoto JF, Sullivan LM, Pencina MJ, Meigs JB, Tofler GH, Selhub J, Jacques PF, Wolf PA, Magnani JW, Ellinor PT, Wang TJ, Levy D, Vasan RS, Benjamin EJ. Relations of biomarkers of distinct pathophysiological pathways and atrial fibrillation incidence in the community. Circulation. 2010 Jan 19; 121(2):200-7.View Related Profiles.

Benjamin, Emelia
Magnani, Jared
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PMID: 20048208; PMCID: PMC3224826; DOI: 10.1161/CIRCULATIONAHA.109.882241;

Thankappan KR, Shah B, Mathur P, Sarma PS, Srinivas G, Mini GK, Daivadanam M, Soman B, Vasan RS. Risk factor profile for chronic non-communicable diseases: results of a community-based study in Kerala, India. Indian J Med Res. 2010 Jan; 131:53-63. PMID: 20167974

Schnabel RB, Baumert J, Barbalic M, Dupuis J, Ellinor PT, Durda P, Dehghan A, Bis JC, Illig T, Morrison AC, Jenny NS, Keaney JF, Gieger C, Tilley C, Yamamoto JF, Khuseyinova N, Heiss G, Doyle M, Blankenberg S, Herder C, Walston JD, Zhu Y, Vasan RS, Klopp N, Boerwinkle E, Larson MG, Psaty BM, Peters A, Ballantyne CM, Witteman JC, Hoogeveen RC, Benjamin EJ, Koenig W, Tracy RP. Duffy antigen receptor for chemokines (Darc) polymorphism regulates circulating concentrations of monocyte chemoattractant protein-1 and other inflammatory mediators. Blood. 2010 Jul 1; 115(26):5289-99.View Related Profiles.

Benjamin, Emelia
Dupuis, Josee
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PMID: 20040767; PMCID: PMC2902130; DOI: 10.1182/blood-2009-05-221382;

Kaptoge S, Di Angelantonio E, Lowe G, Pepys MB, Thompson SG, Collins R, Danesh J. C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis. Lancet. 2010 Jan 9; 375(9709):132-40. PMID: 20031199; PMCID: PMC3162187; DOI: 10.1016/S0140-6736(09)61717-7;

Sofat R, Hingorani AD, Smeeth L, Humphries SE, Talmud PJ, Cooper J, Shah T, Sandhu MS, Ricketts SL, Boekholdt SM, Wareham N, Khaw KT, Kumari M, Kivimaki M, Marmot M, Asselbergs FW, van der Harst P, Dullaart RP, Navis G, van Veldhuisen DJ, Van Gilst WH, Thompson JF, McCaskie P, Palmer LJ, Arca M, Quagliarini F, Gaudio C, Cambien F, Nicaud V, Poirer O, Gudnason V, Isaacs A, Witteman JC, van Duijn CM, Pencina M, Vasan RS, D'Agostino RB, Ordovas J, Li TY, Kakko S, Kauma H, Savolainen MJ, Kesäniemi YA, Sandhofer A, Paulweber B, Sorli JV, Goto A, Yokoyama S, Okumura K, Horne BD, Packard C, Freeman D, Ford I, Sattar N, McCormack V, Lawlor DA, Ebrahim S, Smith GD, Kastelein JJ, Deanfield J, Casas JP. Separating the mechanism-based and off-target actions of cholesteryl ester transfer protein inhibitors with CETP gene polymorphisms. Circulation. 2010 Jan 5; 121(1):52-62.View Related Profiles.

Pencina, Michael
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PMID: 20026784; PMCID: PMC2811869; DOI: 10.1161/CIRCULATIONAHA.109.865444;

Lieb W, Beiser AS, Vasan RS, Tan ZS, Au R, Harris TB, Roubenoff R, Auerbach S, DeCarli C, Wolf PA, Seshadri S. Association of plasma leptin levels with incident Alzheimer disease and MRI measures of brain aging. JAMA. 2009 Dec 16; 302(23):2565-72.View Related Profiles.

Beiser, Alexa
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PMID: 20009056; PMCID: PMC2838501; DOI: 10.1001/jama.2009.1836;

Vasan RS, Pencina MJ, Robins SJ, Zachariah JP, Kaur G, D'Agostino RB, Ordovas JM. Association of circulating cholesteryl ester transfer protein activity with incidence of cardiovascular disease in the community. Circulation. 2009 Dec 15; 120(24):2414-20.View Related Profiles.

Jasuja, Guneet
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PMID: 19948972; PMCID: PMC2818786; DOI: 10.1161/CIRCULATIONAHA.109.872705;

Velagaleti RS, Massaro J, Vasan RS, Robins SJ, Kannel WB, Levy D. Relations of lipid concentrations to heart failure incidence: the Framingham Heart Study. Circulation. 2009 Dec 8; 120(23):2345-51.View Related Profiles.

Massaro, Joseph
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PMID: 19933936; PMCID: PMC3600834; DOI: 10.1161/CIRCULATIONAHA.109.830984;

Taylor HA, Coady SA, Levy D, Walker ER, Vasan RS, Liu J, Akylbekova EL, Garrison RJ, Fox C. Relationships of BMI to cardiovascular risk factors differ by ethnicity. Obesity (Silver Spring). 2010 Aug; 18(8):1638-45. PMID: 19927137; PMCID: PMC3716014; DOI: 10.1038/oby.2009.407;

Di Angelantonio E, Sarwar N, Perry P, Kaptoge S, Ray KK, Thompson A, Wood AM, Lewington S, Sattar N, Packard CJ, Collins R, Thompson SG, Danesh J. Major lipids, apolipoproteins, and risk of vascular disease. JAMA. 2009 Nov 11; 302(18):1993-2000. PMID: 19903920; PMCID: PMC3284229; DOI: 10.1001/jama.2009.1619;

Kannel WB, Vasan RS. Is age really a non-modifiable cardiovascular risk factor? Am J Cardiol. 2009 Nov 1; 104(9):1307-10. PMID: 19840582; PMCID: PMC3760670; DOI: 10.1016/j.amjcard.2009.06.051;

Chami HA, Keyes MJ, Vita JA, Mitchell GF, Larson MG, Fan S, Vasan RS, O'Connor GT, Benjamin EJ, Gottlieb DJ. Brachial artery diameter, blood flow and flow-mediated dilation in sleep-disordered breathing. Vasc Med. 2009 Nov; 14(4):351-60.View Related Profiles.

Gottlieb, Daniel
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PMID: 19808720; PMCID: PMC2956304; DOI: 10.1177/1358863X09105132;

Tadros TM, Massaro JM, Rosito GA, Hoffmann U, Vasan RS, Larson MG, Keaney JF, Lipinska I, Meigs JB, Kathiresan S, O'Donnell CJ, Fox CS, Benjamin EJ. Pericardial fat volume correlates with inflammatory markers: the Framingham Heart Study. Obesity (Silver Spring). 2010 May; 18(5):1039-45.View Related Profiles.

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PMID: 19875999; PMCID: PMC3014610; DOI: 10.1038/oby.2009.343;

Cheng S, Massaro JM, Fox CS, Larson MG, Keyes MJ, McCabe EL, Robins SJ, O'Donnell CJ, Hoffmann U, Jacques PF, Booth SL, Vasan RS, Wolf M, Wang TJ. Adiposity, cardiometabolic risk, and vitamin D status: the Framingham Heart Study. Diabetes. 2010 Jan; 59(1):242-8.View Related Profiles.

O'Donnell, Christopher
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PMID: 19833894; PMCID: PMC2797928; DOI: 10.2337/db09-1011;

Vasan RS, Demissie S, Kimura M, Cupples LA, White C, Gardner JP, Cao X, Levy D, Benjamin EJ, Aviv A. Association of leukocyte telomere length with echocardiographic left ventricular mass: the Framingham heart study. Circulation. 2009 Sep 29; 120(13):1195-202.View Related Profiles.

Benjamin, Emelia
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PMID: 19752323; PMCID: PMC2857693; DOI: 10.1161/CIRCULATIONAHA.109.853895;

Pikula A, Böger RH, Beiser AS, Maas R, DeCarli C, Schwedhelm E, Himali JJ, Schulze F, Au R, Kelly-Hayes M, Kase CS, Vasan RS, Wolf PA, Seshadri S. Association of plasma ADMA levels with MRI markers of vascular brain injury: Framingham offspring study. Stroke. 2009 Sep; 40(9):2959-64.View Related Profiles.

Pikula, Aleksandra
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PMID: 19644064; PMCID: PMC2749945; DOI: 10.1161/STROKEAHA.109.557116;

Erqou S, Kaptoge S, Perry PL, Di Angelantonio E, Thompson A, White IR, Marcovina SM, Collins R, Thompson SG, Danesh J. Lipoprotein(a) concentration and the risk of coronary heart disease, stroke, and nonvascular mortality. JAMA. 2009 Jul 22; 302(4):412-23. PMID: 19622820; PMCID: PMC3272390; DOI: 10.1001/jama.2009.1063;

Vasan RS, Kannel WB. Strategies for cardiovascular risk assessment and prevention over the life course: progress amid imperfections. Circulation. 2009 Aug 4; 120(5):360-3. PMID: 19620497; DOI: 10.1161/CIRCULATIONAHA.109.881995;

Upadhyay A, Hwang SJ, Mitchell GF, Vasan RS, Vita JA, Stantchev PI, Meigs JB, Larson MG, Levy D, Benjamin EJ, Fox CS. Arterial stiffness in mild-to-moderate CKD. J Am Soc Nephrol. 2009 Sep; 20(9):2044-53.View Related Profiles.

Upadhyay, Ashish
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PMID: 19608701; PMCID: PMC2736768; DOI: 10.1681/ASN.2009010074;

Benjamin EJ, Rice KM, Arking DE, Pfeufer A, van Noord C, Smith AV, Schnabel RB, Bis JC, Boerwinkle E, Sinner MF, Dehghan A, Lubitz SA, D'Agostino RB, Lumley T, Ehret GB, Heeringa J, Aspelund T, Newton-Cheh C, Larson MG, Marciante KD, Soliman EZ, Rivadeneira F, Wang TJ, Eiríksdottir G, Levy D, Psaty BM, Li M, Chamberlain AM, Hofman A, Vasan RS, Harris TB, Rotter JI, Kao WH, Agarwal SK, Stricker BH, Wang K, Launer LJ, Smith NL, Chakravarti A, Uitterlinden AG, Wolf PA, Sotoodehnia N, Köttgen A, van Duijn CM, Meitinger T, Mueller M, Perz S, Steinbeck G, Wichmann HE, Lunetta KL, Heckbert SR, Gudnason V, Alonso A, Kääb S, Ellinor PT, Witteman JC. Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry. Nat Genet. 2009 Aug; 41(8):879-81.View Related Profiles.

Benjamin, Emelia
Lunetta, Kathryn
Larson, Martin
Wolf, Philip
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 19597492; PMCID: PMC2761746; DOI: 10.1038/ng.416;

Vasan RS, Glazer NL, Felix JF, Lieb W, Wild PS, Felix SB, Watzinger N, Larson MG, Smith NL, Dehghan A, Grosshennig A, Schillert A, Teumer A, Schmidt R, Kathiresan S, Lumley T, Aulchenko YS, König IR, Zeller T, Homuth G, Struchalin M, Aragam J, Bis JC, Rivadeneira F, Erdmann J, Schnabel RB, Dörr M, Zweiker R, Lind L, Rodeheffer RJ, Greiser KH, Levy D, Haritunians T, Deckers JW, Stritzke J, Lackner KJ, Völker U, Ingelsson E, Kullo I, Haerting J, O'Donnell CJ, Heckbert SR, Stricker BH, Ziegler A, Reffelmann T, Redfield MM, Werdan K, Mitchell GF, Rice K, Arnett DK, Hofman A, Gottdiener JS, Uitterlinden AG, Meitinger T, Blettner M, Friedrich N, Wang TJ, Psaty BM, van Duijn CM, Wichmann HE, Munzel TF, Kroemer HK, Benjamin EJ, Rotter JI, Witteman JC, Schunkert H, Schmidt H, Völzke H, Blankenberg S. Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data. JAMA. 2009 Jul 8; 302(2):168-78.View Related Profiles.

O'Donnell, Christopher
Benjamin, Emelia
Aragam, Jayashri
Larson, Martin
Glazer, Nicole
Ramachandran, Vasan

PMID: 19584346; PMCID: PMC2975567; DOI: 10.1001/jama.2009.978-a;

Parikh NI, Hwang SJ, Ingelsson E, Benjamin EJ, Fox CS, Vasan RS, Murabito JM. Breastfeeding in infancy and adult cardiovascular disease risk factors. Am J Med. 2009 Jul; 122(7):656-63.e1.View Related Profiles.

Benjamin, Emelia
Murabito, Joanne
Hwang, Shih-Jen
Ramachandran, Vasan

PMID: 19559168; PMCID: PMC2704490; DOI: 10.1016/j.amjmed.2008.11.034;

Govindaraju DR, Larson MG, Yin X, Benjamin EJ, Rao MB, Vasan RS. Association between SNP heterozygosity and quantitative traits in the Framingham Heart Study. Ann Hum Genet. 2009 Jul; 73(Pt 4):465-73.View Related Profiles.

Benjamin, Emelia
Larson, Martin
Ramachandran, Vasan
Yin, Xiaoyan

PMID: 19523151; PMCID: PMC3760672; DOI: 10.1111/j.1469-1809.2009.00514.x;

Kannel WB, Vasan RS. Triglycerides as vascular risk factors: new epidemiologic insights. Curr Opin Cardiol. 2009 Jul; 24(4):345-50. PMID: 19424059; PMCID: PMC3012388; DOI: 10.1097/HCO.0b013e32832c1284;

Heard-Costa NL, Zillikens MC, Monda KL, Johansson A, Harris TB, Fu M, Haritunians T, Feitosa MF, Aspelund T, Eiriksdottir G, Garcia M, Launer LJ, Smith AV, Mitchell BD, McArdle PF, Shuldiner AR, Bielinski SJ, Boerwinkle E, Brancati F, Demerath EW, Pankow JS, Arnold AM, Chen YD, Glazer NL, McKnight B, Psaty BM, Rotter JI, Amin N, Campbell H, Gyllensten U, Pattaro C, Pramstaller PP, Rudan I, Struchalin M, Vitart V, Gao X, Kraja A, Province MA, Zhang Q, Atwood LD, Dupuis J, Hirschhorn JN, Jaquish CE, O'Donnell CJ, Vasan RS, White CC, Aulchenko YS, Estrada K, Hofman A, Rivadeneira F, Uitterlinden AG, Witteman JC, Oostra BA, Kaplan RC, Gudnason V, O'Connell JR, Borecki IB, van Duijn CM, Cupples LA, Fox CS, North KE. NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium. PLoS Genet. 2009 Jun; 5(6):e1000539.View Related Profiles.

O'Donnell, Christopher
Dupuis, Josee
Cupples, L
Atwood, Larry
Heard-Costa, Nancy
Glazer, Nicole
Ramachandran, Vasan

PMID: 19557197; PMCID: PMC2695005; DOI: 10.1371/journal.pgen.1000539;

Fox CS, Hwang SJ, Massaro JM, Lieb K, Vasan RS, O'Donnell CJ, Hoffmann U. Relation of subcutaneous and visceral adipose tissue to coronary and abdominal aortic calcium (from the Framingham Heart Study). Am J Cardiol. 2009 Aug 15; 104(4):543-7.View Related Profiles.

O'Donnell, Christopher
Massaro, Joseph
Hwang, Shih-Jen
Ramachandran, Vasan

PMID: 19660609; PMCID: PMC2723724; DOI: 10.1016/j.amjcard.2009.04.019;

Cheng S, Keyes MJ, Larson MG, McCabe EL, Newton-Cheh C, Levy D, Benjamin EJ, Vasan RS, Wang TJ. Long-term outcomes in individuals with prolonged PR interval or first-degree atrioventricular block. JAMA. 2009 Jun 24; 301(24):2571-7.View Related Profiles.

Benjamin, Emelia
Larson, Martin
Ramachandran, Vasan

PMID: 19549974; PMCID: PMC2765917; DOI: 10.1001/jama.2009.888;

Lieb W, Sullivan LM, Aragam J, Harris TB, Roubenoff R, Benjamin EJ, Vasan RS. Relation of serum leptin with cardiac mass and left atrial dimension in individuals >70 years of age. Am J Cardiol. 2009 Aug 15; 104(4):602-5.View Related Profiles.

Benjamin, Emelia
Aragam, Jayashri
Sullivan, Lisa
Ramachandran, Vasan

PMID: 19660619; PMCID: PMC2745631; DOI: 10.1016/j.amjcard.2009.04.026;

Schwedhelm E, Xanthakis V, Maas R, Sullivan LM, Schulze F, Riederer U, Benndorf RA, Böger RH, Vasan RS. Asymmetric dimethylarginine reference intervals determined with liquid chromatography-tandem mass spectrometry: results from the Framingham offspring cohort. Clin Chem. 2009 Aug; 55(8):1539-45.View Related Profiles.

Sullivan, Lisa
Xanthakis, Vanessa
Ramachandran, Vasan

PMID: 19541865; PMCID: PMC3794429; DOI: 10.1373/clinchem.2009.124263;

Pencina MJ, D'Agostino RB, Larson MG, Massaro JM, Vasan RS. Predicting the 30-year risk of cardiovascular disease: the framingham heart study. Circulation. 2009 Jun 23; 119(24):3078-84.View Related Profiles.

Massaro, Joseph
Larson, Martin
Pencina, Michael
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 19506114; PMCID: PMC2748236; DOI: 10.1161/CIRCULATIONAHA.108.816694;

Lieb W, Xanthakis V, Sullivan LM, Aragam J, Pencina MJ, Larson MG, Benjamin EJ, Vasan RS. Longitudinal tracking of left ventricular mass over the adult life course: clinical correlates of short- and long-term change in the framingham offspring study. Circulation. 2009 Jun 23; 119(24):3085-92.View Related Profiles.

Benjamin, Emelia
Aragam, Jayashri
Sullivan, Lisa
Larson, Martin
Pencina, Michael
Xanthakis, Vanessa
Ramachandran, Vasan

PMID: 19506113; PMCID: PMC2761217; DOI: 10.1161/CIRCULATIONAHA.108.824243;

Lee DS, Gona P, Vasan RS, Larson MG, Benjamin EJ, Wang TJ, Tu JV, Levy D. Relation of disease pathogenesis and risk factors to heart failure with preserved or reduced ejection fraction: insights from the framingham heart study of the national heart, lung, and blood institute. Circulation. 2009 Jun 23; 119(24):3070-7.View Related Profiles.

Benjamin, Emelia
Larson, Martin
Ramachandran, Vasan

PMID: 19506115; PMCID: PMC2775498; DOI: 10.1161/CIRCULATIONAHA.108.815944;

Maas R, Xanthakis V, Polak JF, Schwedhelm E, Sullivan LM, Benndorf R, Schulze F, Vasan RS, Wolf PA, Böger RH, Seshadri S. Association of the endogenous nitric oxide synthase inhibitor ADMA with carotid artery intimal media thickness in the Framingham Heart Study offspring cohort. Stroke. 2009 Aug; 40(8):2715-9.View Related Profiles.

Polak, Joseph
Sullivan, Lisa
Wolf, Philip
Seshadri, Sudha
Xanthakis, Vanessa
Ramachandran, Vasan

PMID: 19498184; PMCID: PMC2749947; DOI: 10.1161/STROKEAHA.109.552539;

Joseph J, Pencina MJ, Wang TJ, Hayes L, Tofler GH, Jacques P, Selhub J, Levy D, D'Agostino RB, Benjamin EJ, Vasan RS. Cross-sectional relations of multiple biomarkers representing distinct biological pathways to plasma markers of collagen metabolism in the community. J Hypertens. 2009 Jun; 27(6):1317-24.View Related Profiles.

Benjamin, Emelia
Pencina, Michael
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 19357531; PMCID: PMC2688088; DOI: 10.1097/HJH.0b013e328329fc20;

Levy D, Ehret GB, Rice K, Verwoert GC, Launer LJ, Dehghan A, Glazer NL, Morrison AC, Johnson AD, Aspelund T, Aulchenko Y, Lumley T, Köttgen A, Vasan RS, Rivadeneira F, Eiriksdottir G, Guo X, Arking DE, Mitchell GF, Mattace-Raso FU, Smith AV, Taylor K, Scharpf RB, Hwang SJ, Sijbrands EJ, Bis J, Harris TB, Ganesh SK, O'Donnell CJ, Hofman A, Rotter JI, Coresh J, Benjamin EJ, Uitterlinden AG, Heiss G, Fox CS, Witteman JC, Boerwinkle E, Wang TJ, Gudnason V, Larson MG, Chakravarti A, Psaty BM, van Duijn CM. Genome-wide association study of blood pressure and hypertension. Nat Genet. 2009 Jun; 41(6):677-87.View Related Profiles.

O'Donnell, Christopher
Benjamin, Emelia
Larson, Martin
Glazer, Nicole
Hwang, Shih-Jen
Ramachandran, Vasan

PMID: 19430479; PMCID: PMC2998712; DOI: 10.1038/ng.384;

Kenchaiah S, Benjamin EJ, Evans JC, Aragam J, Vasan RS. Epidemiology of left ventricular false tendons: clinical correlates in the Framingham Heart Study. J Am Soc Echocardiogr. 2009 Jun; 22(6):739-45.View Related Profiles.

Benjamin, Emelia
Aragam, Jayashri
Kenchaiah, Satish
Ramachandran, Vasan

PMID: 19423290; PMCID: PMC2722746; DOI: 10.1016/j.echo.2009.03.008;

Schnabel RB, Larson MG, Yamamoto JF, Kathiresan S, Rong J, Levy D, Keaney JF, Wang TJ, Vasan RS, Benjamin EJ. Relation of multiple inflammatory biomarkers to incident atrial fibrillation. Am J Cardiol. 2009 Jul 1; 104(1):92-6.View Related Profiles.

Benjamin, Emelia
Larson, Martin
Ramachandran, Vasan

PMID: 19576326; PMCID: PMC2802058; DOI: 10.1016/j.amjcard.2009.02.053;

Butler J, Kalogeropoulos A, Georgiopoulou V, de Rekeneire N, Rodondi N, Smith AL, Hoffmann U, Kanaya A, Newman AB, Kritchevsky SB, Vasan RS, Wilson PW, Harris TB. Serum resistin concentrations and risk of new onset heart failure in older persons: the health, aging, and body composition (Health ABC) study. Arterioscler Thromb Vasc Biol. 2009 Jul; 29(7):1144-9. PMID: 19372460; PMCID: PMC2757290; DOI: 10.1161/ATVBAHA.109.186783;

Kalogeropoulos A, Georgiopoulou V, Kritchevsky SB, Psaty BM, Smith NL, Newman AB, Rodondi N, Satterfield S, Bauer DC, Bibbins-Domingo K, Smith AL, Wilson PW, Vasan RS, Harris TB, Butler J. Epidemiology of incident heart failure in a contemporary elderly cohort: the health, aging, and body composition study. Arch Intern Med. 2009 Apr 13; 169(7):708-15. PMID: 19365001; PMCID: PMC2756793; DOI: 10.1001/archinternmed.2009.40;

Schnabel RB, Lunetta KL, Larson MG, Dupuis J, Lipinska I, Rong J, Chen MH, Zhao Z, Yamamoto JF, Meigs JB, Nicaud V, Perret C, Zeller T, Blankenberg S, Tiret L, Keaney JF, Vasan RS, Benjamin EJ. The relation of genetic and environmental factors to systemic inflammatory biomarker concentrations. Circ Cardiovasc Genet. 2009 Jun; 2(3):229-37.View Related Profiles.

Benjamin, Emelia
Dupuis, Josee
Lunetta, Kathryn
Larson, Martin
Chen, Ming-Huei
Ramachandran, Vasan

PMID: 20031590; PMCID: PMC2897047; DOI: 10.1161/CIRCGENETICS.108.804245;

Böger RH, Sullivan LM, Schwedhelm E, Wang TJ, Maas R, Benjamin EJ, Schulze F, Xanthakis V, Benndorf RA, Vasan RS. Plasma asymmetric dimethylarginine and incidence of cardiovascular disease and death in the community. Circulation. 2009 Mar 31; 119(12):1592-600.View Related Profiles.

Benjamin, Emelia
Sullivan, Lisa
Xanthakis, Vanessa
Ramachandran, Vasan

PMID: 19289633; PMCID: PMC2742491; DOI: 10.1161/CIRCULATIONAHA.108.838268;

Parikh NI, Keyes MJ, Larson MG, Pou KM, Hamburg NM, Vita JA, O'Donnell CJ, Vasan RS, Mitchell GF, Hoffmann U, Fox CS, Benjamin EJ. Visceral and subcutaneous adiposity and brachial artery vasodilator function. Obesity (Silver Spring). 2009 Nov; 17(11):2054-9.View Related Profiles.

O'Donnell, Christopher
Benjamin, Emelia
Vita, Joseph
Larson, Martin
Hamburg, Naomi
Ramachandran, Vasan

PMID: 19282819; PMCID: PMC3086764; DOI: 10.1038/oby.2009.60;

Ingelsson E, Sundström J, Melhus H, Michaëlsson K, Berne C, Vasan RS, Risérus U, Blomhoff R, Lind L, Arnlöv J. Circulating retinol-binding protein 4, cardiovascular risk factors and prevalent cardiovascular disease in elderly. Atherosclerosis. 2009 Sep; 206(1):239-44. PMID: 19339013; DOI: 10.1016/j.atherosclerosis.2009.02.029;

Romero JR, Beiser A, Seshadri S, Benjamin EJ, Polak JF, Vasan RS, Au R, DeCarli C, Wolf PA. Carotid artery atherosclerosis, MRI indices of brain ischemia, aging, and cognitive impairment: the Framingham study. Stroke. 2009 May; 40(5):1590-6.View Related Profiles.

Beiser, Alexa
Benjamin, Emelia
Romero, Jose
Polak, Joseph
Wolf, Philip
Au, Rhoda
Seshadri, Sudha
Ramachandran, Vasan

PMID: 19265054; PMCID: PMC2705324; DOI: 10.1161/STROKEAHA.108.535245;

Schnabel RB, Sullivan LM, Levy D, Pencina MJ, Massaro JM, D'Agostino RB, Newton-Cheh C, Yamamoto JF, Magnani JW, Tadros TM, Kannel WB, Wang TJ, Ellinor PT, Wolf PA, Vasan RS, Benjamin EJ. Development of a risk score for atrial fibrillation (Framingham Heart Study): a community-based cohort study. Lancet. 2009 Feb 28; 373(9665):739-45.View Related Profiles.

Benjamin, Emelia
Magnani, Jared
Massaro, Joseph
Sullivan, Lisa
Pencina, Michael
Wolf, Philip
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 19249635; PMCID: PMC2764235; DOI: 10.1016/S0140-6736(09)60443-8;

Porter SA, Massaro JM, Hoffmann U, Vasan RS, O'Donnel CJ, Fox CS. Abdominal subcutaneous adipose tissue: a protective fat depot? Diabetes Care. 2009 Jun; 32(6):1068-75.View Related Profiles.

Massaro, Joseph
Ramachandran, Vasan

PMID: 19244087; PMCID: PMC2681034; DOI: 10.2337/dc08-2280;

Parikh NI, Gona P, Larson MG, Fox CS, Benjamin EJ, Murabito JM, O'Donnell CJ, Vasan RS, Levy D. Long-term trends in myocardial infarction incidence and case fatality in the National Heart, Lung, and Blood Institute's Framingham Heart study. Circulation. 2009 Mar 10; 119(9):1203-10.View Related Profiles.

O'Donnell, Christopher
Benjamin, Emelia
Murabito, Joanne
Larson, Martin
Ramachandran, Vasan

PMID: 19237656; PMCID: PMC2725400; DOI: 10.1161/CIRCULATIONAHA.108.825364;

Lieb W, Safa R, Benjamin EJ, Xanthakis V, Yin X, Sullivan LM, Larson MG, Smith HM, Vita JA, Mitchell GF, Sawyer DB, Vasan RS. Vascular endothelial growth factor, its soluble receptor, and hepatocyte growth factor: clinical and genetic correlates and association with vascular function. Eur Heart J. 2009 May; 30(9):1121-7.View Related Profiles.

Benjamin, Emelia
Vita, Joseph
Sullivan, Lisa
Larson, Martin
Xanthakis, Vanessa
Ramachandran, Vasan
Yin, Xiaoyan

PMID: 19223316; PMCID: PMC2721714; DOI: 10.1093/eurheartj/ehp007;

Jain SH, Massaro JM, Hoffmann U, Rosito GA, Vasan RS, Raji A, O'Donnell CJ, Meigs JB, Fox CS. Cross-sectional associations between abdominal and thoracic adipose tissue compartments and adiponectin and resistin in the Framingham Heart Study. Diabetes Care. 2009 May; 32(5):903-8.View Related Profiles.

O'Donnell, Christopher
Massaro, Joseph
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PMID: 19223612; PMCID: PMC2671095; DOI: 10.2337/dc08-1733;

Dhingra R, Pencina MJ, Schrader P, Wang TJ, Levy D, Pencina K, Siwik DA, Colucci WS, Benjamin EJ, Vasan RS. Relations of matrix remodeling biomarkers to blood pressure progression and incidence of hypertension in the community. Circulation. 2009 Mar 3; 119(8):1101-7.View Related Profiles.

Siwik, Deborah
Benjamin, Emelia
Pencina, Michael
Ramachandran, Vasan
Colucci, Wilson

PMID: 19221217; PMCID: PMC2729705; DOI: 10.1161/CIRCULATIONAHA.108.821769;

Liu E, McKeown NM, Newby PK, Meigs JB, Vasan RS, Quatromoni PA, D'Agostino RB, Jacques PF. Cross-sectional association of dietary patterns with insulin-resistant phenotypes among adults without diabetes in the Framingham Offspring Study. Br J Nutr. 2009 Aug; 102(4):576-83.View Related Profiles.

Quatromoni, Paula
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 19216828; PMCID: PMC3785063; DOI: 10.1017/S0007114509220836;

Newton-Cheh C, Larson MG, Vasan RS, Levy D, Bloch KD, Surti A, Guiducci C, Kathiresan S, Benjamin EJ, Struck J, Morgenthaler NG, Bergmann A, Blankenberg S, Kee F, Nilsson P, Yin X, Peltonen L, Vartiainen E, Salomaa V, Hirschhorn JN, Melander O, Wang TJ. Association of common variants in NPPA and NPPB with circulating natriuretic peptides and blood pressure. Nat Genet. 2009 Mar; 41(3):348-53.View Related Profiles.

Benjamin, Emelia
Larson, Martin
Ramachandran, Vasan
Yin, Xiaoyan

PMID: 19219041; PMCID: PMC2664511; DOI: 10.1038/ng.328;

Ingelsson E, Massaro JM, Sutherland P, Jacques PF, Levy D, D'Agostino RB, Vasan RS, Robins SJ. Contemporary trends in dyslipidemia in the Framingham Heart Study. Arch Intern Med. 2009 Feb 9; 169(3):279-86.View Related Profiles.

Levy, Daniel
Massaro, Joseph
D'Agostino, Ralph
Robins, Sander
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PMID: 19204219; PMCID: PMC3048065; DOI: 10.1001/archinternmed.2008.561;

Peter I, Kelley-Hedgepeth A, Huggins GS, Housman DE, Mendelsohn ME, Vita JA, Vasan RS, Levy D, Benjamin EJ, Mitchell GF. Association between arterial stiffness and variations in oestrogen-related genes. J Hum Hypertens. 2009 Oct; 23(10):636-44.View Related Profiles.

Benjamin, Emelia
Vita, Joseph
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PMID: 19194457; PMCID: PMC2746260; DOI: 10.1038/jhh.2009.1;

Lieb W, Manning AK, Florez JC, Dupuis J, Cupples LA, McAteer JB, Vasan RS, Hoffmann U, O'Donnell CJ, Meigs JB, Fox CS. Variants in the CNR1 and the FAAH genes and adiposity traits in the community. Obesity (Silver Spring). 2009 Apr; 17(4):755-60.View Related Profiles.

O'Donnell, Christopher
Dupuis, Josee
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PMID: 19165169; PMCID: PMC3039277; DOI: 10.1038/oby.2008.608;

Vasan RS. Commentary: C-reactive protein and risk prediction--moving beyond associations to assessing predictive utility and clinical usefulness. Int J Epidemiol. 2009 Feb; 38(1):231-4. PMID: 19129265; PMCID: PMC2639367; DOI: 10.1093/ije/dyn353;

Romero JR, Vasan RS, Beiser AS, Au R, Benjamin EJ, DeCarli C, Wolf PA, Seshadri S. Association of matrix metalloproteinases with MRI indices of brain ischemia and aging. Neurobiol Aging. 2010 Dec; 31(12):2128-35.View Related Profiles.

Beiser, Alexa
Benjamin, Emelia
Romero, Jose
Wolf, Philip
Au, Rhoda
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PMID: 19128858; PMCID: PMC2891210; DOI: 10.1016/j.neurobiolaging.2008.11.004;

Tan ZS, Vasan RS. Thyroid function and Alzheimer's disease. J Alzheimers Dis. 2009; 16(3):503-7. PMID: 19276542; DOI: 10.3233/JAD-2009-0991;

Kelley-Hedgepeth A, Peter I, Montefusco MC, Levy D, Benjamin EJ, Vasan RS, Mendelsohn ME, Housman D, Huggins GS, Mitchell GF. The KCNMB1 E65K variant is associated with reduced central pulse pressure in the community-based Framingham Offspring Cohort. J Hypertens. 2009 Jan; 27(1):55-60.View Related Profiles.

Benjamin, Emelia
Ramachandran, Vasan

PMID: 19050450; PMCID: PMC2637763; DOI: 10.1097/HJH.0b013e328317c8ae;

Vasan RS. A Risk Score for Risk Factors. Rationale and Roadmap for Preventing Hypertension. Hypertension. 2009; 54(3):454-6.

Chen TH, Gona P, Sutherland PA, Benjamin EJ, Wilson PW, Larson MG, Vasan RS, Robins SJ. Long-term C-reactive protein variability and prediction of metabolic risk. Am J Med. 2009 Jan; 122(1):53-61.View Related Profiles.

Benjamin, Emelia
Larson, Martin
Robins, Sander
Chen, Ting-hsu
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PMID: 19114172; PMCID: PMC2654380; DOI: 10.1016/j.amjmed.2008.08.023;

Pencina MJ, D'Agostino RB, Sr., D'Agostino RB, Jr., Vasan RS. Response to 'Net reclassification improvement and decision theory' by Vickers et al. Stat Med. 2009; 28:526-528.

Franklin SS, Lopez VA, Wong ND, Mitchell GF, Larson MG, Vasan RS, Levy D. Single versus combined blood pressure components and risk for cardiovascular disease: the Framingham Heart Study. Circulation. 2009 Jan 20; 119(2):243-50.View Related Profiles.

Larson, Martin
Ramachandran, Vasan

PMID: 19118251; PMCID: PMC3042701; DOI: 10.1161/CIRCULATIONAHA.108.797936;

Lieb W, Sullivan LM, Harris TB, Roubenoff R, Benjamin EJ, Levy D, Fox CS, Wang TJ, Wilson PW, Kannel WB, Vasan RS. Plasma leptin levels and incidence of heart failure, cardiovascular disease, and total mortality in elderly individuals. Diabetes Care. 2009 Apr; 32(4):612-6.View Related Profiles.

Benjamin, Emelia
Sullivan, Lisa
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PMID: 19114611; PMCID: PMC2660448; DOI: 10.2337/dc08-1596;

Frankel DS, Vasan RS, D'Agostino RB, Benjamin EJ, Levy D, Wang TJ, Meigs JB. Resistin, adiponectin, and risk of heart failure the Framingham offspring study. J Am Coll Cardiol. 2009 Mar 3; 53(9):754-62.View Related Profiles.

Benjamin, Emelia
D'Agostino, Ralph
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PMID: 19245965; PMCID: PMC2676793; DOI: 10.1016/j.jacc.2008.07.073;

Dietrich M, Jacques PF, Pencina MJ, Lanier K, Keyes MJ, Kaur G, Wolf PA, D'Agostino RB, Vasan RS. Vitamin E supplement use and the incidence of cardiovascular disease and all-cause mortality in the Framingham Heart Study: Does the underlying health status play a role? Atherosclerosis. 2009 Aug; 205(2):549-53.View Related Profiles.

Jasuja, Guneet
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PMID: 19195657; PMCID: PMC2717181; DOI: 10.1016/j.atherosclerosis.2008.12.019;

Ingelsson E, Arnlöv J, Zethelius B, Vasan RS, Flyvbjerg A, Frystyk J, Berne C, Hänni A, Lind L, Sundström J. Associations of serum adiponectin with skeletal muscle morphology and insulin sensitivity. J Clin Endocrinol Metab. 2009 Mar; 94(3):953-7. PMID: 19106268; DOI: 10.1210/jc.2008-1772;

Lieb W, Larson MG, Benjamin EJ, Yin X, Tofler GH, Selhub J, Jacques PF, Wang TJ, Vita JA, Levy D, Vasan RS, Mitchell GF. Multimarker approach to evaluate correlates of vascular stiffness: the Framingham Heart Study. Circulation. 2009 Jan 6; 119(1):37-43.View Related Profiles.

Benjamin, Emelia
Vita, Joseph
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PMID: 19103986; PMCID: PMC2722113; DOI: 10.1161/CIRCULATIONAHA.108.816108;

Molenaar EA, Massaro JM, Jacques PF, Pou KM, Ellison RC, Hoffmann U, Pencina K, Shadwick SD, Vasan RS, O'Donnell CJ, Fox CS. Association of lifestyle factors with abdominal subcutaneous and visceral adiposity: the Framingham Heart Study. Diabetes Care. 2009 Mar; 32(3):505-10.View Related Profiles.

O'Donnell, Christopher
Massaro, Joseph
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PMID: 19074991; PMCID: PMC2646037; DOI: 10.2337/dc08-1382;

Pou KM, Massaro JM, Hoffmann U, Lieb K, Vasan RS, O'Donnell CJ, Fox CS. Patterns of abdominal fat distribution: the Framingham Heart Study. Diabetes Care. 2009 Mar; 32(3):481-5.View Related Profiles.

O'Donnell, Christopher
Massaro, Joseph
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PMID: 19074995; PMCID: PMC2646033; DOI: 10.2337/dc08-1359;

Kannel WB, Vasan RS. Adverse consequences of the 50% misconception. Am J Cardiol. 2009 Feb 1; 103(3):426-7. PMID: 19166702; PMCID: PMC3753109; DOI: 10.1016/j.amjcard.2008.09.098;

Velagaleti RS, Gona P, Levy D, Aragam J, Larson MG, Tofler GH, Lieb W, Wang TJ, Benjamin EJ, Vasan RS. Relations of biomarkers representing distinct biological pathways to left ventricular geometry. Circulation. 2008 Nov 25; 118(22):2252-8, 5p following 2258.View Related Profiles.

Benjamin, Emelia
Aragam, Jayashri
Larson, Martin
Velagaleti, Raghava
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PMID: 19001021; PMCID: PMC2747641; DOI: 10.1161/CIRCULATIONAHA.108.817411;

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PMID: 17903302; PMCID: PMC1995621; DOI: 10.1186/1471-2350-8-S1-S3;

Fox CS, Heard-Costa N, Cupples LA, Dupuis J, Vasan RS, Atwood LD. Genome-wide association to body mass index and waist circumference: the Framingham Heart Study 100K project. BMC Med Genet. 2007; 8 Suppl 1:S18.View Related Profiles.

Dupuis, Josee
Cupples, L
Heard-Costa, Nancy
Ramachandran, Vasan

PMID: 17903300; PMCID: PMC1995618; DOI: 10.1186/1471-2350-8-S1-S18;

Danesh J, Erqou S, Walker M, Thompson SG, Tipping R, Ford C, Pressel S, Walldius G, Jungner I, Folsom AR, Chambless LE, Knuiman M, Whincup PH, Wannamethee SG, Morris RW, Willeit J, Kiechl S, Santer P, Mayr A, Wald N, Ebrahim S, Lawlor DA, Yarnell JW, Gallacher J, Casiglia E, Tikhonoff V, Nietert PJ, Sutherland SE, Bachman DL, Keil JE, Cushman M, Psaty BM, Tracy RP, Tybjaerg-Hansen A, Nordestgaard BG, Frikke-Schmidt R, Giampaoli S, Palmieri L, Panico S, Vanuzzo D, Pilotto L, Simons L, McCallum J, Friedlander Y, Fowkes FG, Lee AJ, Smith FB, Taylor J, Guralnik J, Phillips C, Wallace R, Blazer D, Khaw KT, Jansson JH, Donfrancesco C, Salomaa V, Harald K, Jousilahti P, Vartiainen E, Woodward M, D'Agostino RB, Wolf PA, Vasan RS, Pencina MJ, Bladbjerg EM, Jorgensen T, Moller L, Jespersen J, Dankner R, Chetrit A, Lubin F, Rosengren A, Wilhelmsen L, Lappas G, Eriksson H, Bjorkelund C, Cremer P, Nagel D, Tilvis R, Strandberg T, Rodriguez B, Bouter LM, Heine RJ, Dekker JM, Nijpels G, Stehouwer CD, Rimm E, Pai J, Sato S, Iso H, Kitamura A, Noda H, Goldbourt U, Salomaa V, Salonen JT, Nyyssönen K, Tuomainen TP, Deeg D, Poppelaars JL, Meade T, Cooper J, Hedblad B, Berglund G, Engstrom G, Döring A, Koenig W, Meisinger C, Mraz W, Kuller L, Selmer R, Tverdal A, Nystad W, Gillum R, Mussolino M, Hankinson S, Manson J, De Stavola B, Knottenbelt C, Cooper JA, Bauer KA, Rosenberg RD, Sato S, Naito Y, Holme I, Nakagawa H, Miura H, Ducimetiere P, Jouven X, Crespo C, Garcia-Palmieri M, Amouyel P, Arveiler D, Evans A, Ferrieres J, Schulte H, Assmann G, Shepherd J, Packard C, Sattar N, Cantin B, Lamarche B, Després JP, Dagenais GR, Barrett-Connor E, Wingard D, Bettencourt R, Gudnason V, Aspelund T, Sigurdsson G, Thorsson B, Trevisan M, Witteman J, Kardys I, Breteler M, Hofman A, Tunstall-Pedoe H, Tavendale R, Lowe GD, Ben-Shlomo Y, Howard BV, Zhang Y, Best L, Umans J, Onat A, Meade TW, Njolstad I, Mathiesen E, Lochen ML, Wilsgaard T, Gaziano JM, Stampfer M, Ridker P, Ulmer H, Diem G, Concin H, Rodeghiero F, Tosetto A, Brunner E, Shipley M, Buring J, Cobbe SM, Ford I, Robertson M, He Y, Ibanez AM, Feskens EJ, Kromhout D, Collins R, Di Angelantonio E, Kaptoge S, Lewington S, Orfei L, Pennells L, Perry P, Ray K, Sarwar N, Scherman M, Thompson A, Watson S, Wensley F, White IR, Wood AM. The Emerging Risk Factors Collaboration: analysis of individual data on lipid, inflammatory and other markers in over 1.1 million participants in 104 prospective studies of cardiovascular diseases. Eur J Epidemiol. 2007; 22(12):839-69.View Related Profiles.

Gaziano, J. Michael
Buring, Julie
Bauer, Kenneth Alan
Pencina, Michael
Wolf, Philip
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 17876711

Pou KM, Massaro JM, Hoffmann U, Vasan RS, Maurovich-Horvat P, Larson MG, Keaney JF, Meigs JB, Lipinska I, Kathiresan S, Murabito JM, O'Donnell CJ, Benjamin EJ, Fox CS. Visceral and subcutaneous adipose tissue volumes are cross-sectionally related to markers of inflammation and oxidative stress: the Framingham Heart Study. Circulation. 2007 Sep 11; 116(11):1234-41.View Related Profiles.

O'Donnell, Christopher
Benjamin, Emelia
Murabito, Joanne
Massaro, Joseph
Larson, Martin
Ramachandran, Vasan

PMID: 17709633

Ingelsson E, Schaefer EJ, Contois JH, McNamara JR, Sullivan L, Keyes MJ, Pencina MJ, Schoonmaker C, Wilson PW, D'Agostino RB, Vasan RS. Clinical utility of different lipid measures for prediction of coronary heart disease in men and women. JAMA. 2007 Aug 15; 298(7):776-85.View Related Profiles.

Sullivan, Lisa
Pencina, Michael
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 17699011

Ingelsson E, Pencina MJ, Tofler GH, Benjamin EJ, Lanier KJ, Jacques PF, Fox CS, Meigs JB, Levy D, Larson MG, Selhub J, D'Agostino RB, Wang TJ, Vasan RS. Multimarker approach to evaluate the incidence of the metabolic syndrome and longitudinal changes in metabolic risk factors: the Framingham Offspring Study. Circulation. 2007 Aug 28; 116(9):984-92.View Related Profiles.

Levy, Daniel
Benjamin, Emelia
Larson, Martin
Pencina, Michael
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 17698726

Wang TJ, Larson MG, Benjamin EJ, Siwik DA, Safa R, Guo CY, Corey D, Sundstrom J, Sawyer DB, Colucci WS, Vasan RS. Clinical and echocardiographic correlates of plasma procollagen type III amino-terminal peptide levels in the community. Am Heart J. 2007 Aug; 154(2):291-7.View Related Profiles.

Siwik, Deborah
Benjamin, Emelia
Larson, Martin
Ramachandran, Vasan
Colucci, Wilson

PMID: 17643579; PMCID: PMC3170820; DOI: 10.1016/j.ahj.2007.04.006;

Dhingra R, Sullivan L, Jacques PF, Wang TJ, Fox CS, Meigs JB, D'Agostino RB, Gaziano JM, Vasan RS. Soft drink consumption and risk of developing cardiometabolic risk factors and the metabolic syndrome in middle-aged adults in the community. Circulation. 2007 Jul 31; 116(5):480-8.View Related Profiles.

Gaziano, J. Michael
Sullivan, Lisa
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 17646581

Pencina MJ, Vasan RS, D'Agostino RB. Algorithms for assessing cardiovascular risk in women. JAMA. 2007 Jul 11; 298(2):175-6; author reply 177-8.View Related Profiles.

Pencina, Michael
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 17622595

Foster MC, Hwang SJ, Larson MG, Parikh NI, Meigs JB, Vasan RS, Wang TJ, Levy D, Fox CS. Cross-classification of microalbuminuria and reduced glomerular filtration rate: associations between cardiovascular disease risk factors and clinical outcomes. Arch Intern Med. 2007 Jul 9; 167(13):1386-92.View Related Profiles.

Larson, Martin
Hwang, Shih-Jen
Ramachandran, Vasan

PMID: 17620532

Ingelsson E, Sullivan LM, Fox CS, Murabito JM, Benjamin EJ, Polak JF, Meigs JB, Keyes MJ, O'Donnell CJ, Wang TJ, D'Agostino RB, Wolf PA, Vasan RS. Burden and prognostic importance of subclinical cardiovascular disease in overweight and obese individuals. Circulation. 2007 Jul 24; 116(4):375-84.View Related Profiles.

O'Donnell, Christopher
Benjamin, Emelia
Murabito, Joanne
Polak, Joseph
Sullivan, Lisa
Wolf, Philip
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 17620505

Meigs JB, Larson MG, Fox CS, Keaney JF, Vasan RS, Benjamin EJ. Association of oxidative stress, insulin resistance, and diabetes risk phenotypes: the Framingham Offspring Study. Diabetes Care. 2007 Oct; 30(10):2529-35.View Related Profiles.

Benjamin, Emelia
Larson, Martin
Ramachandran, Vasan

PMID: 17586736

Fox CS, Massaro JM, Hoffmann U, Pou KM, Maurovich-Horvat P, Liu CY, Vasan RS, Murabito JM, Meigs JB, Cupples LA, D'Agostino RB, O'Donnell CJ. Abdominal visceral and subcutaneous adipose tissue compartments: association with metabolic risk factors in the Framingham Heart Study. Circulation. 2007 Jul 3; 116(1):39-48.View Related Profiles.

O'Donnell, Christopher
Liu, Chunyu
Murabito, Joanne
Massaro, Joseph
Cupples, L
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 17576866

Widlansky ME, Vita JA, Keyes MJ, Larson MG, Hamburg NM, Levy D, Mitchell GF, Osypiuk EW, Vasan RS, Benjamin EJ. Relation of season and temperature to endothelium-dependent flow-mediated vasodilation in subjects without clinical evidence of cardiovascular disease (from the Framingham Heart Study). Am J Cardiol. 2007 Aug 1; 100(3):518-23.View Related Profiles.

Levy, Daniel
Benjamin, Emelia
Osypiuk, Ewa
Vita, Joseph
Larson, Martin
Hamburg, Naomi
Ramachandran, Vasan

PMID: 17659939; PMCID: PMC1994775; DOI: 10.1016/j.amjcard.2007.03.055;

Ingelsson E, Larson MG, Vasan RS, O'Donnell CJ, Yin X, Hirschhorn JN, Newton-Cheh C, Drake JA, Musone SL, Heard-Costa NL, Benjamin EJ, Levy D, Atwood LD, Wang TJ, Kathiresan S. Heritability, linkage, and genetic associations of exercise treadmill test responses. Circulation. 2007 Jun 12; 115(23):2917-24.View Related Profiles.

O'Donnell, Christopher
Benjamin, Emelia
Larson, Martin
Heard-Costa, Nancy
Ramachandran, Vasan
Yin, Xiaoyan

PMID: 17548724

Tan ZS, Beiser AS, Vasan RS, Roubenoff R, Dinarello CA, Harris TB, Benjamin EJ, Au R, Kiel DP, Wolf PA, Seshadri S. Inflammatory markers and the risk of Alzheimer disease: the Framingham Study. Neurology. 2007 May 29; 68(22):1902-8.View Related Profiles.

Beiser, Alexa
Benjamin, Emelia
Wolf, Philip
Seshadri, Sudha
Ramachandran, Vasan

PMID: 17536046

Levy D, Hwang SJ, Kayalar A, Benjamin EJ, Vasan RS, Parise H, Larson MG, Wang TJ, Selhub J, Jacques PF, Vita JA, Keyes MJ, Mitchell GF. Associations of plasma natriuretic peptide, adrenomedullin, and homocysteine levels with alterations in arterial stiffness: the Framingham Heart Study. Circulation. 2007 Jun 19; 115(24):3079-85.View Related Profiles.

Benjamin, Emelia
Vita, Joseph
Larson, Martin
Hwang, Shih-Jen
Ramachandran, Vasan

PMID: 17533184

Vasan RS, Kannel WB. Are guidelines effectively guiding antihypertensive therapy? Am J Cardiol. 2007 Jul 1; 100(1):143-4. PMID: 17599457

Dhingra R, Sullivan LM, Fox CS, Wang TJ, D'Agostino RB, Gaziano JM, Vasan RS. Relations of serum phosphorus and calcium levels to the incidence of cardiovascular disease in the community. Arch Intern Med. 2007 May 14; 167(9):879-85.View Related Profiles.

Gaziano, J. Michael
Sullivan, Lisa
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 17502528

Cobain MR, Pencina MJ, D'Agostino RB, Vasan RS. Lifetime risk for developing dyslipidemia: the Framingham Offspring Study. Am J Med. 2007 Jul; 120(7):623-30.View Related Profiles.

Pencina, Michael
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 17602937

Mitchell GF, Guo CY, Benjamin EJ, Larson MG, Keyes MJ, Vita JA, Vasan RS, Levy D. Cross-sectional correlates of increased aortic stiffness in the community: the Framingham Heart Study. Circulation. 2007 May 22; 115(20):2628-36.View Related Profiles.

Benjamin, Emelia
Vita, Joseph
Larson, Martin
Ramachandran, Vasan

PMID: 17485578

Thakore AH, Guo CY, Larson MG, Corey D, Wang TJ, Vasan RS, D'Agostino RB, Lipinska I, Keaney JF, Benjamin EJ, O'Donnell CJ. Association of multiple inflammatory markers with carotid intimal medial thickness and stenosis (from the Framingham Heart Study). Am J Cardiol. 2007 Jun 1; 99(11):1598-602.View Related Profiles.

O'Donnell, Christopher
Benjamin, Emelia
Larson, Martin
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 17531588

Mitchell GF, Guo CY, Kathiresan S, Vasan RS, Larson MG, Vita JA, Keyes MJ, Vyas M, Newton-Cheh C, Musone SL, Camargo AL, Drake JA, Levy D, O'Donnell CJ, Hirschhorn JN, Benjamin EJ. Vascular stiffness and genetic variation at the endothelial nitric oxide synthase locus: the Framingham Heart study. Hypertension. 2007 Jun; 49(6):1285-90.View Related Profiles.

O'Donnell, Christopher
Benjamin, Emelia
Vita, Joseph
Larson, Martin
Ramachandran, Vasan

PMID: 17404185

Wolf PA, Beiser A, Elias MF, Au R, Vasan RS, Seshadri S. Relation of obesity to cognitive function: importance of central obesity and synergistic influence of concomitant hypertension. The Framingham Heart Study. Curr Alzheimer Res. 2007 Apr; 4(2):111-6.View Related Profiles.

Beiser, Alexa
Wolf, Philip
Au, Rhoda
Seshadri, Sudha
Ramachandran, Vasan

PMID: 17430232

Jefferson AL, Massaro JM, Wolf PA, Seshadri S, Au R, Vasan RS, Larson MG, Meigs JB, Keaney JF, Lipinska I, Kathiresan S, Benjamin EJ, DeCarli C. Inflammatory biomarkers are associated with total brain volume: the Framingham Heart Study. Neurology. 2007 Mar 27; 68(13):1032-8.View Related Profiles.

Benjamin, Emelia
Massaro, Joseph
Larson, Martin
Wolf, Philip
Au, Rhoda
Seshadri, Sudha
Ramachandran, Vasan

PMID: 17389308; PMCID: PMC2758770; DOI: 10.1212/01.wnl.0000257815.20548.df;

Splansky GL, Corey D, Yang Q, Atwood LD, Cupples LA, Benjamin EJ, D'Agostino RB, Fox CS, Larson MG, Murabito JM, O'Donnell CJ, Vasan RS, Wolf PA, Levy D. The Third Generation Cohort of the National Heart, Lung, and Blood Institute's Framingham Heart Study: design, recruitment, and initial examination. Am J Epidemiol. 2007 Jun 1; 165(11):1328-35.View Related Profiles.

O'Donnell, Christopher
Levy, Daniel
Benjamin, Emelia
Murabito, Joanne
Cupples, L
Larson, Martin
Wolf, Philip
Yang, Qiong
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 17372189

Peter I, Huggins GS, Shearman AM, Pollak A, Schmid CH, Cupples LA, Demissie S, Patten RD, Karas RH, Housman DE, Mendelsohn ME, Vasan RS, Benjamin EJ. Age-related changes in echocardiographic measurements: association with variation in the estrogen receptor-alpha gene. Hypertension. 2007 May; 49(5):1000-6.View Related Profiles.

Benjamin, Emelia
Cupples, L
Demissie, Serkalem
Ramachandran, Vasan

PMID: 17372038

Ingelsson E, Sullivan LM, Murabito JM, Fox CS, Benjamin EJ, Polak JF, Meigs JB, Keyes MJ, O'Donnell CJ, Wang TJ, D'Agostino RB, Wolf PA, Vasan RS. Prevalence and prognostic impact of subclinical cardiovascular disease in individuals with the metabolic syndrome and diabetes. Diabetes. 2007 Jun; 56(6):1718-26.View Related Profiles.

O'Donnell, Christopher
Benjamin, Emelia
Murabito, Joanne
Polak, Joseph
Sullivan, Lisa
Wolf, Philip
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 17369522

Terry DF, Evans JC, Pencina MJ, Murabito JM, Vasan RS, Wolf PA, Kelly-Hayes M, Levy D, D'Agostino RB, Benjamin EJ. Characteristics of Framingham offspring participants with long-lived parents. Arch Intern Med. 2007 Mar 12; 167(5):438-44.View Related Profiles.

Levy, Daniel
Terry, Dellara
Benjamin, Emelia
Murabito, Joanne
Kelly-Hayes, Margaret
Pencina, Michael
Wolf, Philip
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 17353490

Fox CS, Coady S, Sorlie PD, D'Agostino RB, Pencina MJ, Vasan RS, Meigs JB, Levy D, Savage PJ. Increasing cardiovascular disease burden due to diabetes mellitus: the Framingham Heart Study. Circulation. 2007 Mar 27; 115(12):1544-50.View Related Profiles.

Pencina, Michael
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 17353438

Wang TJ, Larson MG, Keyes MJ, Levy D, Benjamin EJ, Vasan RS. Association of plasma natriuretic peptide levels with metabolic risk factors in ambulatory individuals. Circulation. 2007 Mar 20; 115(11):1345-53.View Related Profiles.

Benjamin, Emelia
Larson, Martin
Ramachandran, Vasan

PMID: 17339551

Parikh NI, Pencina MJ, Wang TJ, Lanier KJ, Fox CS, D'Agostino RB, Vasan RS. Increasing trends in incidence of overweight and obesity over 5 decades. Am J Med. 2007 Mar; 120(3):242-50.View Related Profiles.

Pencina, Michael
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 17349447

Mitchell GF, Vasan RS, Keyes MJ, Parise H, Wang TJ, Larson MG, D'Agostino RB, Kannel WB, Levy D, Benjamin EJ. Pulse pressure and risk of new-onset atrial fibrillation. JAMA. 2007 Feb 21; 297(7):709-15.View Related Profiles.

Benjamin, Emelia
Larson, Martin
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 17312290

Newton-Cheh C, Guo CY, Gona P, Larson MG, Benjamin EJ, Wang TJ, Kathiresan S, O'Donnell CJ, Musone SL, Camargo AL, Drake JA, Levy D, Hirschhorn JN, Vasan RS. Clinical and genetic correlates of aldosterone-to-renin ratio and relations to blood pressure in a community sample. Hypertension. 2007 Apr; 49(4):846-56.View Related Profiles.

O'Donnell, Christopher
Levy, Daniel
Benjamin, Emelia
Larson, Martin
Ramachandran, Vasan

PMID: 17296870

Ingelsson E, Larson MG, Fox CS, Yin X, Wang TJ, Lipinska I, Pou KM, Hoffmann U, Benjamin EJ, Keaney JF, Vasan RS. Clinical correlates of circulating visfatin levels in a community-based sample. Diabetes Care. 2007 May; 30(5):1278-80.View Related Profiles.

Benjamin, Emelia
Larson, Martin
Ramachandran, Vasan
Yin, Xiaoyan

PMID: 17261750

Wang TJ, Gona P, Larson MG, Levy D, Benjamin EJ, Tofler GH, Jacques PF, Meigs JB, Rifai N, Selhub J, Robins SJ, Newton-Cheh C, Vasan RS. Multiple biomarkers and the risk of incident hypertension. Hypertension. 2007 Mar; 49(3):432-8.View Related Profiles.

Benjamin, Emelia
Larson, Martin
Robins, Sander
Ramachandran, Vasan

PMID: 17242302

Elias MF, Sullivan LM, Elias PK, D'Agostino RB, Wolf PA, Seshadri S, Au R, Benjamin EJ, Vasan RS. Left ventricular mass, blood pressure, and lowered cognitive performance in the Framingham offspring. Hypertension. 2007 Mar; 49(3):439-45.View Related Profiles.

Benjamin, Emelia
Sullivan, Lisa
Wolf, Philip
D'Agostino, Ralph
Au, Rhoda
Seshadri, Sudha
Ramachandran, Vasan

PMID: 17224472

Lipska K, Sylaja PN, Sarma PS, Thankappan KR, Kutty VR, Vasan RS, Radhakrishnan K. Risk factors for acute ischaemic stroke in young adults in South India. J Neurol Neurosurg Psychiatry. 2007 Sep; 78(9):959-63. PMID: 17220290; PMCID: PMC2117871; DOI: 10.1136/jnnp.2006.106831;

Cupples LA, Arruda HT, Benjamin EJ, D'Agostino RB, Demissie S, DeStefano AL, Dupuis J, Falls KM, Fox CS, Gottlieb DJ, Govindaraju DR, Guo CY, Heard-Costa NL, Hwang SJ, Kathiresan S, Kiel DP, Laramie JM, Larson MG, Levy D, Liu CY, Lunetta KL, Mailman MD, Manning AK, Meigs JB, Murabito JM, Newton-Cheh C, O'Connor GT, O'Donnell CJ, Pandey M, Seshadri S, Vasan RS, Wang ZY, Wilk JB, Wolf PA, Yang Q, Atwood LD. The Framingham Heart Study 100K SNP genome-wide association study resource: overview of 17 phenotype working group reports. BMC Med Genet. 2007; 8 Suppl 1:S1.View Related Profiles.

DeStefano, Anita
O'Donnell, Christopher
Liu, Chunyu
Benjamin, Emelia
O'Connor, George
Murabito, Joanne
Dupuis, Josee
Lunetta, Kathryn
Cupples, L
Larson, Martin
Heard-Costa, Nancy
Wolf, Philip
Yang, Qiong
D'Agostino, Ralph
Demissie, Serkalem
Hwang, Shih-Jen
Seshadri, Sudha
Ramachandran, Vasan

PMID: 17903291; PMCID: PMC1995613; DOI: 10.1186/1471-2350-8-S1-S1;

Pencina,M.J., D',A.R., Sr., D',A.R., Jr., and Vasan R.S. Comments on 'Integrated discrimination and net reclassification improvements-Practical advice'. Stat Med. 2007.

Wang TJ, Gona P, Larson MG, Tofler GH, Levy D, Newton-Cheh C, Jacques PF, Rifai N, Selhub J, Robins SJ, Benjamin EJ, D'Agostino RB, Vasan RS. Multiple biomarkers for the prediction of first major cardiovascular events and death. N Engl J Med. 2006 Dec 21; 355(25):2631-9.View Related Profiles.

Benjamin, Emelia
Larson, Martin
D'Agostino, Ralph
Robins, Sander
Ramachandran, Vasan

PMID: 17182988

Pencina MJ, D'Agostino RB, Beiser AS, Cobain MR, Vasan RS. Estimating lifetime risk of developing high serum total cholesterol: adjustment for baseline prevalence and single-occasion measurements. Am J Epidemiol. 2007 Feb 15; 165(4):464-72.View Related Profiles.

Beiser, Alexa
Pencina, Michael
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 17116649

Lee DS, Evans JC, Robins SJ, Wilson PW, Albano I, Fox CS, Wang TJ, Benjamin EJ, D'Agostino RB, Vasan RS. Gamma glutamyl transferase and metabolic syndrome, cardiovascular disease, and mortality risk: the Framingham Heart Study. Arterioscler Thromb Vasc Biol. 2007 Jan; 27(1):127-33.View Related Profiles.

Benjamin, Emelia
D'Agostino, Ralph
Robins, Sander
Ramachandran, Vasan

PMID: 17095717

Patwardhan AA, Larson MG, Levy D, Benjamin EJ, Leip EP, Keyes MJ, Wang TJ, Gottlieb DJ, Vasan RS. Obstructive sleep apnea and plasma natriuretic peptide levels in a community-based sample. Sleep. 2006 Oct; 29(10):1301-6.View Related Profiles.

Patwardhan, Anjali
Levy, Daniel
Benjamin, Emelia
Larson, Martin
Ramachandran, Vasan

PMID: 17068983

Arnlöv J, Evans JC, Benjamin EJ, Larson MG, Levy D, Sutherland P, Siwik DA, Wang TJ, Colucci WS, Vasan RS. Clinical and echocardiographic correlates of plasma osteopontin in the community: the Framingham Heart Study. Heart. 2006 Oct; 92(10):1514-5.View Related Profiles.

Siwik, Deborah
Benjamin, Emelia
Larson, Martin
Ramachandran, Vasan
Colucci, Wilson

PMID: 16973806; PMCID: PMC1861062; DOI: 10.1136/hrt.2005.081406;

Elias MF, Sullivan LM, Elias PK, Vasan RS, D'Agostino RB, Seshadri S, Au R, Wolf PA, Benjamin EJ. Atrial fibrillation is associated with lower cognitive performance in the Framingham offspring men. J Stroke Cerebrovasc Dis. 2006 Sep-Oct; 15(5):214-22.View Related Profiles.

Benjamin, Emelia
Sullivan, Lisa
Wolf, Philip
D'Agostino, Ralph
Au, Rhoda
Seshadri, Sudha
Ramachandran, Vasan

PMID: 17904078

Kannel WB, Vasan RS. Aggressive lowering of blood pressure. Lancet. 2006 Aug 19; 368(9536):627-8. PMID: 16920451

Lee DS, Vasan RS. Goals and guidelines for treating hypertension in a patient with heart failure. Curr Treat Options Cardiovasc Med. 2006 Aug; 8(4):334-44. PMID: 17038273

Arnlöv J, Pencina MJ, Amin S, Nam BH, Benjamin EJ, Murabito JM, Wang TJ, Knapp PE, D'Agostino RB, Bhasin S, Vasan RS. Endogenous sex hormones and cardiovascular disease incidence in men. Ann Intern Med. 2006 Aug 1; 145(3):176-84.View Related Profiles.

Benjamin, Emelia
Murabito, Joanne
Pencina, Michael
Knapp, Philip
D'Agostino, Ralph
Bhasin, Shalender
Ramachandran, Vasan

PMID: 16880459

Lee DS, Pencina MJ, Benjamin EJ, Wang TJ, Levy D, O'Donnell CJ, Nam BH, Larson MG, D'Agostino RB, Vasan RS. Association of parental heart failure with risk of heart failure in offspring. N Engl J Med. 2006 Jul 13; 355(2):138-47.View Related Profiles.

O'Donnell, Christopher
Benjamin, Emelia
Larson, Martin
Pencina, Michael
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 16837677

Fox CS, Pencina MJ, Meigs JB, Vasan RS, Levitzky YS, D'Agostino RB. Trends in the incidence of type 2 diabetes mellitus from the 1970s to the 1990s: the Framingham Heart Study. Circulation. 2006 Jun 27; 113(25):2914-8.View Related Profiles.

Pencina, Michael
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 16785337

Morita H, Larson MG, Barr SC, Vasan RS, O'Donnell CJ, Hirschhorn JN, Levy D, Corey D, Seidman CE, Seidman JG, Benjamin EJ. Single-gene mutations and increased left ventricular wall thickness in the community: the Framingham Heart Study. Circulation. 2006 Jun 13; 113(23):2697-705.View Related Profiles.

O'Donnell, Christopher
Benjamin, Emelia
Larson, Martin
Ramachandran, Vasan

PMID: 16754800

Fox CS, Larson MG, Hwang SJ, Leip EP, Rifai N, Levy D, Benjamin EJ, Murabito JM, Meigs JB, Vasan RS. Cross-sectional relations of serum aldosterone and urine sodium excretion to urinary albumin excretion in a community-based sample. Kidney Int. 2006 Jun; 69(11):2064-9.View Related Profiles.

Benjamin, Emelia
Murabito, Joanne
Larson, Martin
Ramachandran, Vasan

PMID: 16572107

Meigs JB, Wilson PW, Fox CS, Vasan RS, Nathan DM, Sullivan LM, D'Agostino RB. Body mass index, metabolic syndrome, and risk of type 2 diabetes or cardiovascular disease. J Clin Endocrinol Metab. 2006 Aug; 91(8):2906-12.View Related Profiles.

Sullivan, Lisa
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 16735483

Levy D, DePalma SR, Benjamin EJ, O'Donnell CJ, Parise H, Hirschhorn JN, Vasan RS, Izumo S, Larson MG. Phenotype-genotype association grid: a convenient method for summarizing multiple association analyses. BMC Genet. 2006; 7:30.View Related Profiles.

O'Donnell, Christopher
Levy, Daniel
Benjamin, Emelia
Larson, Martin
Ramachandran, Vasan

PMID: 16716207; PMCID: PMC1526453; DOI: 10.1186/1471-2156-7-30;

Vasan RS. Biomarkers of cardiovascular disease: molecular basis and practical considerations. Circulation. 2006 May 16; 113(19):2335-62. PMID: 16702488

Dhingra R, Pencina MJ, Wang TJ, Nam BH, Benjamin EJ, Levy D, Larson MG, Kannel WB, D'Agostino RB, Vasan RS. Electrocardiographic QRS duration and the risk of congestive heart failure: the Framingham Heart Study. Hypertension. 2006 May; 47(5):861-7.View Related Profiles.

Benjamin, Emelia
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PMID: 16585411

Lee DS, Wang TJ, Vasan RS. Screening for ventricular remodeling. Curr Heart Fail Rep. 2006 Apr; 3(1):5-13. PMID: 16684491

Fox CS, Guo CY, Larson MG, Vasan RS, Parise H, O'Donnell CJ, D'Agostino RB, Keaney JF, Benjamin EJ. Relations of inflammation and novel risk factors to valvular calcification. Am J Cardiol. 2006 May 15; 97(10):1502-5.View Related Profiles.

O'Donnell, Christopher
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Kathiresan S, Larson MG, Vasan RS, Guo CY, Gona P, Keaney JF, Wilson PW, Newton-Cheh C, Musone SL, Camargo AL, Drake JA, Levy D, O'Donnell CJ, Hirschhorn JN, Benjamin EJ. Contribution of clinical correlates and 13 C-reactive protein gene polymorphisms to interindividual variability in serum C-reactive protein level. Circulation. 2006 Mar 21; 113(11):1415-23.View Related Profiles.

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Kathiresan S, Gona P, Larson MG, Vita JA, Mitchell GF, Tofler GH, Levy D, Newton-Cheh C, Wang TJ, Benjamin EJ, Vasan RS. Cross-sectional relations of multiple biomarkers from distinct biological pathways to brachial artery endothelial function. Circulation. 2006 Feb 21; 113(7):938-45.View Related Profiles.

Benjamin, Emelia
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PMID: 16476848

Dhingra R, Larson MG, Benjamin EJ, Lipinska I, Gona P, Corey D, Keaney JF, Vasan RS. Cross-sectional correlates of serum heat shock protein 70 in the community. Am J Hypertens. 2006 Feb; 19(2):227-31; discussion 232-3.View Related Profiles.

Benjamin, Emelia
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Sundström J, Vasan RS. Circulating biomarkers of extracellular matrix remodeling and risk of atherosclerotic events. Curr Opin Lipidol. 2006 Feb; 17(1):45-53. PMID: 16407715

Loucks EB, Sullivan LM, Hayes LJ, D'Agostino RB, Larson MG, Vasan RS, Benjamin EJ, Berkman LF. Association of educational level with inflammatory markers in the Framingham Offspring Study. Am J Epidemiol. 2006 Apr 1; 163(7):622-8.View Related Profiles.

Benjamin, Emelia
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PMID: 16421236

Thankappan KR, Sivasankaran S, Sarma PS, Mini G, Khader SA, Padmanabhan P, Vasan R. Prevalence-correlates-awareness-treatment and control of hypertension in kumarakom, kerala: baseline results of a community-based intervention program. Indian Heart J. 2006 Jan-Feb; 58(1):28-33. PMID: 18984927

Atilla K, Vasan RS. Prehypertension and risk of cardiovascular disease. Expert Rev Cardiovasc Ther. 2006 Jan; 4(1):111-7. PMID: 16375633

Fox CS, Larson MG, Vasan RS, Guo CY, Parise H, Levy D, Leip EP, O'donnell CJ, D'Agostino RB, Benjamin EJ. Cross-sectional association of kidney function with valvular and annular calcification: the Framingham heart study. J Am Soc Nephrol. 2006 Feb; 17(2):521-7.View Related Profiles.

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PMID: 16382018

Kathiresan S, Otvos JD, Sullivan LM, Keyes MJ, Schaefer EJ, Wilson PW, D'Agostino RB, Vasan RS, Robins SJ. Increased small low-density lipoprotein particle number: a prominent feature of the metabolic syndrome in the Framingham Heart Study. Circulation. 2006 Jan 3; 113(1):20-9.View Related Profiles.

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Mitchell GF, Vita JA, Larson MG, Parise H, Keyes MJ, Warner E, Vasan RS, Levy D, Benjamin EJ. Cross-sectional relations of peripheral microvascular function, cardiovascular disease risk factors, and aortic stiffness: the Framingham Heart Study. Circulation. 2005 Dec 13; 112(24):3722-8.View Related Profiles.

Benjamin, Emelia
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PMID: 16330686

Peter I, Shearman AM, Zucker DR, Schmid CH, Demissie S, Cupples LA, Larson MG, Vasan RS, D'Agostino RB, Karas RH, Mendelsohn ME, Housman DE, Levy D. Variation in estrogen-related genes and cross-sectional and longitudinal blood pressure in the Framingham Heart Study. J Hypertens. 2005 Dec; 23(12):2193-200.View Related Profiles.

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Terry DF, Pencina MJ, Vasan RS, Murabito JM, Wolf PA, Hayes MK, Levy D, D'Agostino RB, Benjamin EJ. Cardiovascular risk factors predictive for survival and morbidity-free survival in the oldest-old Framingham Heart Study participants. J Am Geriatr Soc. 2005 Nov; 53(11):1944-50.View Related Profiles.

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PMID: 16274376

Peter I, Shearman AM, Vasan RS, Zucker DR, Schmid CH, Demissie S, Cupples LA, Kuvin JT, Karas RH, Mendelsohn ME, Housman DE, Benjamin EJ. Association of estrogen receptor beta gene polymorphisms with left ventricular mass and wall thickness in women. Am J Hypertens. 2005 Nov; 18(11):1388-95.View Related Profiles.

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Vasan RS, Pencina MJ, Cobain M, Freiberg MS, D'Agostino RB. Estimated risks for developing obesity in the Framingham Heart Study. Ann Intern Med. 2005 Oct 4; 143(7):473-80.View Related Profiles.

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Wang TJ, Vasan RS. Epidemiology of uncontrolled hypertension in the United States. Circulation. 2005 Sep 13; 112(11):1651-62. PMID: 16157784

Arnlöv J, Pencina MJ, Nam BH, Meigs JB, Fox CS, Levy D, D'Agostino RB, Vasan RS. Relations of insulin sensitivity to longitudinal blood pressure tracking: variations with baseline age, body mass index, and blood pressure. Circulation. 2005 Sep 20; 112(12):1719-27.View Related Profiles.

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Wulsin LR, Evans JC, Vasan RS, Murabito JM, Kelly-Hayes M, Benjamin EJ. Depressive symptoms, coronary heart disease, and overall mortality in the Framingham Heart Study. Psychosom Med. 2005 Sep-Oct; 67(5):697-702.View Related Profiles.

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PMID: 16204426

Kathiresan S, Larson MG, Vasan RS, Guo CY, Vita JA, Mitchell GF, Keyes MJ, Newton-Cheh C, Musone SL, Lochner AL, Drake JA, Levy D, O'Donnell CJ, Hirschhorn JN, Benjamin EJ. Common genetic variation at the endothelial nitric oxide synthase locus and relations to brachial artery vasodilator function in the community. Circulation. 2005 Sep 6; 112(10):1419-27.View Related Profiles.

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McDermott DH, Yang Q, Kathiresan S, Cupples LA, Massaro JM, Keaney JF, Larson MG, Vasan RS, Hirschhorn JN, O'Donnell CJ, Murphy PM, Benjamin EJ. CCL2 polymorphisms are associated with serum monocyte chemoattractant protein-1 levels and myocardial infarction in the Framingham Heart Study. Circulation. 2005 Aug 23; 112(8):1113-20.View Related Profiles.

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Arnlöv J, Evans JC, Meigs JB, Wang TJ, Fox CS, Levy D, Benjamin EJ, D'Agostino RB, Vasan RS. Low-grade albuminuria and incidence of cardiovascular disease events in nonhypertensive and nondiabetic individuals: the Framingham Heart Study. Circulation. 2005 Aug 16; 112(7):969-75.View Related Profiles.

Benjamin, Emelia
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Mitchell GF, DeStefano AL, Larson MG, Benjamin EJ, Chen MH, Vasan RS, Vita JA, Levy D. Heritability and a genome-wide linkage scan for arterial stiffness, wave reflection, and mean arterial pressure: the Framingham Heart Study. Circulation. 2005 Jul 12; 112(2):194-9.View Related Profiles.

DeStefano, Anita
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PMID: 15998672

Lee DS, Vasan RS. Novel markers for heart failure diagnosis and prognosis. Curr Opin Cardiol. 2005 May; 20(3):201-10. PMID: 15861008

Kathiresan S, Larson MG, Benjamin EJ, Corey D, Murabito JM, Fox CS, Wilson PW, Rifai N, Meigs JB, Ricken G, Lifton RP, Levy D, Vasan RS. Clinical and genetic correlates of serum aldosterone in the community: the Framingham Heart Study. Am J Hypertens. 2005 May; 18(5 Pt 1):657-65.View Related Profiles.

Benjamin, Emelia
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PMID: 15882548

Dupuis J, Larson MG, Vasan RS, Massaro JM, Wilson PW, Lipinska I, Corey D, Vita JA, Keaney JF, Benjamin EJ. Genome scan of systemic biomarkers of vascular inflammation in the Framingham Heart Study: evidence for susceptibility loci on 1q. Atherosclerosis. 2005 Oct; 182(2):307-14.View Related Profiles.

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PMID: 16159603

Fox CS, Heard-Costa NL, Vasan RS, Murabito JM, D'Agostino RB, Atwood LD. Genomewide linkage analysis of weight change in the Framingham Heart Study. J Clin Endocrinol Metab. 2005 Jun; 90(6):3197-201.View Related Profiles.

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Vasan RS, Sullivan LM, Wilson PW, Sempos CT, Sundström J, Kannel WB, Levy D, D'Agostino RB. Relative importance of borderline and elevated levels of coronary heart disease risk factors. Ann Intern Med. 2005 Mar 15; 142(6):393-402.View Related Profiles.

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Dhingra R, Ho Nam B, Benjamin EJ, Wang TJ, Larson MG, D'Agostino RB, Levy D, Vasan RS. Cross-sectional relations of electrocardiographic QRS duration to left ventricular dimensions: the Framingham Heart Study. J Am Coll Cardiol. 2005 Mar 1; 45(5):685-9.View Related Profiles.

Levy, Daniel
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PMID: 15734611

Wang TJ, Evans JC, Meigs JB, Rifai N, Fox CS, D'Agostino RB, Levy D, Vasan RS. Low-grade albuminuria and the risks of hypertension and blood pressure progression. Circulation. 2005 Mar 22; 111(11):1370-6.View Related Profiles.

D'Agostino, Ralph
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Franklin SS, Pio JR, Wong ND, Larson MG, Leip EP, Vasan RS, Levy D. Predictors of new-onset diastolic and systolic hypertension: the Framingham Heart Study. Circulation. 2005 Mar 8; 111(9):1121-7.View Related Profiles.

Larson, Martin
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PMID: 15723980

Arnlöv J, Vasan RS. Neurohormonal activation in populations susceptible to heart failure. Heart Fail Clin. 2005 Apr; 1(1):11-23. PMID: 17386830

Mitchell GF, Warner E, Parise H, Vita JA, Keaney JF, Jr., Keyes MJ, Levy D, Larson MG, Vasan RS, Benjamin EJ. Response: Flow-Mediated Dilation: Just a Marker of Local Shear Stress?. Hypertension. 2005; 45:e11-e12.
Vasan RS, D'Agostino RB, Sr. Age and time need not and should not be eliminated from the coronary risk prediction models. Circulation. 2005; 111:542-545.

Sundström J, Vasan RS. Homocysteine and heart failure: a review of investigations from the Framingham Heart Study. Clin Chem Lab Med. 2005; 43(10):987-92. PMID: 16197286

Freiberg MS, Cabral HJ, Heeren TC, Vasan RS, Curtis Ellison R. Alcohol consumption and the prevalence of the Metabolic Syndrome in the US.: a cross-sectional analysis of data from the Third National Health and Nutrition Examination Survey. Diabetes Care. 2004 Dec; 27(12):2954-9.View Related Profiles.

Cabral, Howard
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Vita JA, Keaney JF, Larson MG, Keyes MJ, Massaro JM, Lipinska I, Lehman BT, Fan S, Osypiuk E, Wilson PW, Vasan RS, Mitchell GF, Benjamin EJ. Brachial artery vasodilator function and systemic inflammation in the Framingham Offspring Study. Circulation. 2004 Dec 7; 110(23):3604-9.View Related Profiles.

Benjamin, Emelia
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PMID: 15569842

Sundström J, Sullivan L, D'Agostino RB, Levy D, Kannel WB, Vasan RS. Relations of serum uric acid to longitudinal blood pressure tracking and hypertension incidence. Hypertension. 2005 Jan; 45(1):28-33.View Related Profiles.

Sullivan, Lisa
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PMID: 15569852

Wang TJ, Parise H, Levy D, D'Agostino RB, Wolf PA, Vasan RS, Benjamin EJ. Obesity and the risk of new-onset atrial fibrillation. JAMA. 2004 Nov 24; 292(20):2471-7.View Related Profiles.

Benjamin, Emelia
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Lloyd-Jones DM, Leip EP, Larson MG, Vasan RS, Levy D. Novel approach to examining first cardiovascular events after hypertension onset. Hypertension. 2005 Jan; 45(1):39-45.View Related Profiles.

Lloyd-Jones, Donald
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Kannel WB, Vasan RS. Assessment of cardiovascular risk and choice of antihypertensive therapy. Curr Hypertens Rep. 2004 Oct; 6(5):346-51. PMID: 15341685

Dhingra R, Pencina MJ, Benjamin EJ, Levy D, Larson MG, Meigs JB, Rifai N, D'Agostino RB, Vasan RS. Cross-sectional relations of urinary sodium excretion to cardiac structure and hypertrophy. The Framingham Heart Study. Am J Hypertens. 2004 Oct; 17(10):891-6.View Related Profiles.

Benjamin, Emelia
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PMID: 15485750

Balady GJ, Larson MG, Vasan RS, Leip EP, O'Donnell CJ, Levy D. Usefulness of exercise testing in the prediction of coronary disease risk among asymptomatic persons as a function of the Framingham risk score. Circulation. 2004 Oct 5; 110(14):1920-5.View Related Profiles.

O'Donnell, Christopher
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Kenchaiah S, Gaziano JM, Vasan RS. Impact of obesity on the risk of heart failure and survival after the onset of heart failure. Med Clin North Am. 2004 Sep; 88(5):1273-94.View Related Profiles.

Gaziano, J. Michael
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Sundström J, Evans JC, Benjamin EJ, Levy D, Larson MG, Sawyer DB, Siwik DA, Colucci WS, Wilson PW, Vasan RS. Relations of plasma total TIMP-1 levels to cardiovascular risk factors and echocardiographic measures: the Framingham heart study. Eur Heart J. 2004 Sep; 25(17):1509-16.View Related Profiles.

Levy, Daniel
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Kenchaiah S, Narula J, Vasan RS. Risk factors for heart failure. Med Clin North Am. 2004 Sep; 88(5):1145-72.View Related Profiles.

Kenchaiah, Satish
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Lloyd-Jones DM, Wang TJ, Leip EP, Larson MG, Levy D, Vasan RS, D'Agostino RB, Massaro JM, Beiser A, Wolf PA, Benjamin EJ. Lifetime risk for development of atrial fibrillation: the Framingham Heart Study. Circulation. 2004 Aug 31; 110(9):1042-6.View Related Profiles.

Beiser, Alexa
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Mitchell GF, Parise H, Vita JA, Larson MG, Warner E, Keaney JF, Keyes MJ, Levy D, Vasan RS, Benjamin EJ. Local shear stress and brachial artery flow-mediated dilation: the Framingham Heart Study. Hypertension. 2004 Aug; 44(2):134-9.View Related Profiles.

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Keaney JF, Massaro JM, Larson MG, Vasan RS, Wilson PW, Lipinska I, Corey D, Sutherland P, Vita JA, Benjamin EJ. Heritability and correlates of intercellular adhesion molecule-1 in the Framingham Offspring Study. J Am Coll Cardiol. 2004 Jul 7; 44(1):168-73.View Related Profiles.

Benjamin, Emelia
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Vasan RS, Evans JC, Larson MG, Wilson PW, Meigs JB, Rifai N, Benjamin EJ, Levy D. Serum aldosterone and the incidence of hypertension in nonhypertensive persons. N Engl J Med. 2004 Jul 1; 351(1):33-41.View Related Profiles.

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DeStefano AL, Larson MG, Mitchell GF, Benjamin EJ, Vasan RS, Li J, Corey D, Levy D. Genome-wide scan for pulse pressure in the National Heart, Lung and Blood Institute's Framingham Heart Study. Hypertension. 2004 Aug; 44(2):152-5.View Related Profiles.

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Fox CS, Parise H, D'Agostino RB, Lloyd-Jones DM, Vasan RS, Wang TJ, Levy D, Wolf PA, Benjamin EJ. Parental atrial fibrillation as a risk factor for atrial fibrillation in offspring. JAMA. 2004 Jun 16; 291(23):2851-5.View Related Profiles.

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Sundström J, Evans JC, Benjamin EJ, Levy D, Larson MG, Sawyer DB, Siwik DA, Colucci WS, Sutherland P, Wilson PW, Vasan RS. Relations of plasma matrix metalloproteinase-9 to clinical cardiovascular risk factors and echocardiographic left ventricular measures: the Framingham Heart Study. Circulation. 2004 Jun 15; 109(23):2850-6.View Related Profiles.

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Morshedi-Meibodi A, Evans JC, Levy D, Larson MG, Vasan RS. Clinical correlates and prognostic significance of exercise-induced ventricular premature beats in the community: the Framingham Heart Study. Circulation. 2004 May 25; 109(20):2417-22.View Related Profiles.

Larson, Martin
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Mitchell GF, Parise H, Benjamin EJ, Larson MG, Keyes MJ, Vita JA, Vasan RS, Levy D. Changes in arterial stiffness and wave reflection with advancing age in healthy men and women: the Framingham Heart Study. Hypertension. 2004 Jun; 43(6):1239-45.View Related Profiles.

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Fox CS, Parise H, Vasan RS, Levy D, O'Donnell CJ, D'Agostino RB, Plehn JF, Benjamin EJ. Mitral annular calcification is a predictor for incident atrial fibrillation. Atherosclerosis. 2004 Apr; 173(2):291-4.View Related Profiles.

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Vasan RS, Evans JC, Benjamin EJ, Levy D, Larson MG, Sundstrom J, Murabito JM, Sam F, Colucci WS, Wilson PW. Relations of serum aldosterone to cardiac structure: gender-related differences in the Framingham Heart Study. Hypertension. 2004 May; 43(5):957-62.View Related Profiles.

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Sundström J, Sullivan L, Selhub J, Benjamin EJ, D'Agostino RB, Jacques PF, Rosenberg IH, Levy D, Wilson PW, Vasan RS. Relations of plasma homocysteine to left ventricular structure and function: the Framingham Heart Study. Eur Heart J. 2004 Mar; 25(6):523-30.View Related Profiles.

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Walsh CR, Larson MG, Kupka MJ, Levy D, Vasan RS, Benjamin EJ, Manning WJ, Clouse ME, O'Donnell CJ. Association of aortic valve calcium detected by electron beam computed tomography with echocardiographic aortic valve disease and with calcium deposits in the coronary arteries and thoracic aorta. Am J Cardiol. 2004 Feb 15; 93(4):421-5.View Related Profiles.

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Wang TJ, Larson MG, Levy D, Benjamin EJ, Leip EP, Omland T, Wolf PA, Vasan RS. Plasma natriuretic peptide levels and the risk of cardiovascular events and death. N Engl J Med. 2004 Feb 12; 350(7):655-63.View Related Profiles.

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Wang TJ, Larson MG, Levy D, Benjamin EJ, Leip EP, Wilson PW, Vasan RS. Impact of obesity on plasma natriuretic peptide levels. Circulation. 2004 Feb 10; 109(5):594-600.View Related Profiles.

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Benjamin EJ, Larson MG, Keyes MJ, Mitchell GF, Vasan RS, Keaney JF, Lehman BT, Fan S, Osypiuk E, Vita JA. Clinical correlates and heritability of flow-mediated dilation in the community: the Framingham Heart Study. Circulation. 2004 Feb 10; 109(5):613-9.View Related Profiles.

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Vasan RS. Expanding indications for natriuretic peptides: importance of better new (research) protocols. Am Heart J. 2004; 148:743-746.
Mitchell GF, Parise H, Benjamin EJ, Larson MG, Keyes MJ, Vita JA, Vasan RS, Levy D. Response. Hypertension. 2004.

Nair VM, Thankappan KR, Vasan RS, Sarma PS. Community utilisation of subcentres in primary health care--an analysis of determinants in Kerala. Indian J Public Health. 2004 Jan-Mar; 48(1):17-20. PMID: 15704721

Sundström J, Sullivan L, D'Agostino RB, Jacques PF, Selhub J, Rosenberg IH, Wilson PW, Levy D, Vasan RS. Plasma homocysteine, hypertension incidence, and blood pressure tracking: the Framingham Heart Study. Hypertension. 2003 Dec; 42(6):1100-5.View Related Profiles.

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Vasan RS, Sullivan LM, D'Agostino RB, Roubenoff R, Harris T, Sawyer DB, Levy D, Wilson PW. Serum insulin-like growth factor I and risk for heart failure in elderly individuals without a previous myocardial infarction: the Framingham Heart Study. Ann Intern Med. 2003 Oct 21; 139(8):642-8.View Related Profiles.

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Kannel WB, Vasan RS, Levy D. Is the relation of systolic blood pressure to risk of cardiovascular disease continuous and graded, or are there critical values? Hypertension. 2003 Oct; 42(4):453-6. PMID: 12975387

Vasan RS, Kannel WB. Recent US and European blood pressure guidelines: implications for developing countries. Natl Med J India. 2003 Sep-Oct; 16(5):241-4. PMID: 14680277

Wang TJ, Massaro JM, Levy D, Vasan RS, Wolf PA, D'Agostino RB, Larson MG, Kannel WB, Benjamin EJ. A risk score for predicting stroke or death in individuals with new-onset atrial fibrillation in the community: the Framingham Heart Study. JAMA. 2003 Aug 27; 290(8):1049-56.View Related Profiles.

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Wang TJ, Evans JC, Benjamin EJ, Levy D, LeRoy EC, Vasan RS. Natural history of asymptomatic left ventricular systolic dysfunction in the community. Circulation. 2003 Aug 26; 108(8):977-82.View Related Profiles.

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Wang TJ, Larson MG, Levy D, Benjamin EJ, Corey D, Leip EP, Vasan RS. Heritability and genetic linkage of plasma natriuretic peptide levels. Circulation. 2003 Jul 8; 108(1):13-6.View Related Profiles.

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Wang TJ, Larson MG, Levy D, Vasan RS, Leip EP, Wolf PA, D'Agostino RB, Murabito JM, Kannel WB, Benjamin EJ. Temporal relations of atrial fibrillation and congestive heart failure and their joint influence on mortality: the Framingham Heart Study. Circulation. 2003 Jun 17; 107(23):2920-5.View Related Profiles.

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Zachariah MG, Thankappan KR, Alex SC, Sarma PS, Vasan RS. Prevalence, correlates, awareness, treatment, and control of hypertension in a middle-aged urban population in Kerala. Indian Heart J. 2003 May-Jun; 55(3):245-51. PMID: 14560934

Freitag MH, Vasan RS. What is normal blood pressure? Curr Opin Nephrol Hypertens. 2003 May; 12(3):285-92. PMID: 12698067

Vasan RS, Larson MG, Levy D, Galderisi M, Wolf PA, Benjamin EJ. Doppler transmitral flow indexes and risk of atrial fibrillation (the Framingham Heart Study). Am J Cardiol. 2003 May 1; 91(9):1079-83.View Related Profiles.

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Ramachandran, Vasan

PMID: 12714150

Fox CS, Vasan RS, Parise H, Levy D, O'Donnell CJ, D'Agostino RB, Benjamin EJ. Mitral annular calcification predicts cardiovascular morbidity and mortality: the Framingham Heart Study. Circulation. 2003 Mar 25; 107(11):1492-6.View Related Profiles.

O'Donnell, Christopher
Benjamin, Emelia
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 12654605

Vasan RS, Sullivan LM, Roubenoff R, Dinarello CA, Harris T, Benjamin EJ, Sawyer DB, Levy D, Wilson PW, D'Agostino RB. Inflammatory markers and risk of heart failure in elderly subjects without prior myocardial infarction: the Framingham Heart Study. Circulation. 2003 Mar 25; 107(11):1486-91.View Related Profiles.

Benjamin, Emelia
Sullivan, Lisa
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 12654604

Vasan RS, Beiser A, D'Agostino RB, Levy D, Selhub J, Jacques PF, Rosenberg IH, Wilson PW. Plasma homocysteine and risk for congestive heart failure in adults without prior myocardial infarction. JAMA. 2003 Mar 12; 289(10):1251-7.View Related Profiles.

Beiser, Alexa
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 12633186

Freitag MH, Larson MG, Levy D, Benjamin EJ, Wang TJ, Leip EP, Wilson PW, Vasan RS. Plasma brain natriuretic peptide levels and blood pressure tracking in the Framingham Heart Study. Hypertension. 2003 Apr; 41(4):978-83.View Related Profiles.

Benjamin, Emelia
Larson, Martin
Ramachandran, Vasan

PMID: 12623868

Keaney JF, Larson MG, Vasan RS, Wilson PW, Lipinska I, Corey D, Massaro JM, Sutherland P, Vita JA, Benjamin EJ. Obesity and systemic oxidative stress: clinical correlates of oxidative stress in the Framingham Study. Arterioscler Thromb Vasc Biol. 2003 Mar 1; 23(3):434-9.View Related Profiles.

Benjamin, Emelia
Vita, Joseph
Massaro, Joseph
Larson, Martin
Ramachandran, Vasan

PMID: 12615693

Rutter MK, Parise H, Benjamin EJ, Levy D, Larson MG, Meigs JB, Nesto RW, Wilson PW, Vasan RS. Impact of glucose intolerance and insulin resistance on cardiac structure and function: sex-related differences in the Framingham Heart Study. Circulation. 2003 Jan 28; 107(3):448-54.View Related Profiles.

Benjamin, Emelia
Larson, Martin
Ramachandran, Vasan

PMID: 12551870

Vasan RS. Cardiac function and obesity. Heart. 2003; 89(2003):1127-1129.

Freitag MH, Vasan RS. Screening for left ventricular systolic dysfunction: the use of B-type natriuretic peptide. Heart Fail Monit. 2003; 4(2):38-44. PMID: 14724717

Vasan RS. Diastolic heart failure. BMJ. 2003; 327:1181-1182.
Wang TJ, Levy D, Benjamin EJ, Vasan RS. The epidemiology of "asymptomatic" left ventricular systolic dysfunction: implications for screening. Ann Intern Med. 2003; 138:907-916.

Lloyd-Jones DM, Larson MG, Leip EP, Beiser A, D'Agostino RB, Kannel WB, Murabito JM, Vasan RS, Benjamin EJ, Levy D. Lifetime risk for developing congestive heart failure: the Framingham Heart Study. Circulation. 2002 Dec 10; 106(24):3068-72.View Related Profiles.

Beiser, Alexa
Lloyd-Jones, Donald
Benjamin, Emelia
Murabito, Joanne
Larson, Martin
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 12473553

Levy D, Kenchaiah S, Larson MG, Benjamin EJ, Kupka MJ, Ho KK, Murabito JM, Vasan RS. Long-term trends in the incidence of and survival with heart failure. N Engl J Med. 2002 Oct 31; 347(18):1397-402.View Related Profiles.

Benjamin, Emelia
Murabito, Joanne
Larson, Martin
Kenchaiah, Satish
Ramachandran, Vasan

PMID: 12409541

Morshedi-Meibodi A, Larson MG, Levy D, O'Donnell CJ, Vasan RS. Heart rate recovery after treadmill exercise testing and risk of cardiovascular disease events (The Framingham Heart Study). Am J Cardiol. 2002 Oct 15; 90(8):848-52.View Related Profiles.

O'Donnell, Christopher
Larson, Martin
Ramachandran, Vasan

PMID: 12372572

Kenchaiah S, Evans JC, Levy D, Wilson PW, Benjamin EJ, Larson MG, Kannel WB, Vasan RS. Obesity and the risk of heart failure. N Engl J Med. 2002 Aug 1; 347(5):305-13.View Related Profiles.

Benjamin, Emelia
Larson, Martin
Kenchaiah, Satish
Ramachandran, Vasan

PMID: 12151467

Walsh CR, Larson MG, Leip EP, Vasan RS, Levy D. Serum potassium and risk of cardiovascular disease: the Framingham heart study. Arch Intern Med. 2002 May 13; 162(9):1007-12.View Related Profiles.

Larson, Martin
Ramachandran, Vasan

PMID: 11996610

Vasan RS, Beiser A, Seshadri S, Larson MG, Kannel WB, D'Agostino RB, Levy D. Residual lifetime risk for developing hypertension in middle-aged women and men: The Framingham Heart Study. JAMA. 2002 Feb 27; 287(8):1003-10.View Related Profiles.

Beiser, Alexa
Larson, Martin
D'Agostino, Ralph
Seshadri, Sudha
Ramachandran, Vasan

PMID: 11866648

Walsh CR, Larson MG, Evans JC, Djousse L, Ellison RC, Vasan RS, Levy D. Alcohol consumption and risk for congestive heart failure in the Framingham Heart Study. Ann Intern Med. 2002 Feb 5; 136(3):181-91.View Related Profiles.

Larson, Martin
Ellison, Robert
Ramachandran, Vasan

PMID: 11827493

Walsh CR, Larson MG, Vasan RS, Levy D. Serum potassium is not associated with blood pressure tracking in the Framingham Heart Study. Am J Hypertens. 2002 Feb; 15(2 Pt 1):130-6.View Related Profiles.

Larson, Martin
Ramachandran, Vasan

PMID: 11863248

Vasan RS, Benjamin EJ, Larson MG, Leip EP, Wang TJ, Wilson PW, Levy D. Plasma natriuretic peptides for community screening for left ventricular hypertrophy and systolic dysfunction: the Framingham heart study. JAMA. 2002; 288:1252-1259.

Vasan RS, Massaro JM, Wilson PW, Seshadri S, Wolf PA, Levy D, D'Agostino RB. Antecedent blood pressure and risk of cardiovascular disease: the Framingham Heart Study . Circulation. 2002 Jan 1; 105(1):48-53.View Related Profiles.

Massaro, Joseph
Wolf, Philip
D'Agostino, Ralph
Seshadri, Sudha
Ramachandran, Vasan

PMID: 11772875

Vasan RS, Levy D. Rates of progression to hypertension among non-hypertensive subjects: implications for blood pressure screening. Eur Heart J. 2002; 23:1067-1070.
Wang TJ, Larson MG, Levy D, Leip EP, Benjamin EJ, Wilson PW, Sutherland P, Omland T, Vasan RS. Impact of age and sex on plasma natriuretic peptide levels in healthy adults. Am J Cardiol. 2002; 90:254-258.

Vasan RS, Larson MG, Leip EP, Kannel WB, Levy D. Assessment of frequency of progression to hypertension in non-hypertensive participants in the Framingham Heart Study: a cohort study. Lancet. 2001 Nov 17; 358(9294):1682-6.View Related Profiles.

Larson, Martin
Ramachandran, Vasan

PMID: 11728544

Vasan RS, Larson MG, Leip EP, Evans JC, O'Donnell CJ, Kannel WB, Levy D. Impact of high-normal blood pressure on the risk of cardiovascular disease. N Engl J Med. 2001 Nov 1; 345(18):1291-7.View Related Profiles.

O'Donnell, Christopher
Larson, Martin
Ramachandran, Vasan

PMID: 11794147

Seshadri S, Wolf PA, Beiser A, Vasan RS, Wilson PW, Kase CS, Kelly-Hayes M, Kannel WB, D'Agostino RB. Elevated midlife blood pressure increases stroke risk in elderly persons: the Framingham Study. Arch Intern Med. 2001 Oct 22; 161(19):2343-50.View Related Profiles.

Beiser, Alexa
Kase, Carlos
Kelly-Hayes, Margaret
Wolf, Philip
D'Agostino, Ralph
Seshadri, Sudha
Ramachandran, Vasan

PMID: 11606150

Nair V, Thankappan K, Sarma P, Vasan R. Changing roles of grass-root level health workers in Kerala, India. Health Policy Plan. 2001; 16:171-179.
Vasan RS, Benjamin EJ. Diastolic heart failure--no time to relax. N Engl J Med. 2001; 344:56-59.

Lal SS, Vasan RS, Sarma PS, Thankappan KR. Knowledge and attitude of college students in Kerala towards HIV/AIDS, sexually transmitted diseases and sexuality. Natl Med J India. 2000 Sep-Oct; 13(5):231-6. PMID: 11190050

Radhakrishnan T, Thankappan KR, Vasan RS, Sarma PS. Socioeconomic and demographic factors associated with birth weight: a community based study in Kerala. Indian Pediatr. 2000 Aug; 37(8):872-6. PMID: 10951635

Vasan RS, Levy D, Larson MG, Benjamin EJ. Interpretation of echocardiographic measurements: a call for standardization. Am Heart J. 2000; 139:412-422.
Vasan RS, Levy D. Defining diastolic heart failure: a call for standardized diagnostic criteria. Circulation. 2000; 101:2118-2121.

Kalavathy MC, Thankappan KR, Sarma PS, Vasan RS. Prevalence, awareness, treatment and control of hypertension in an elderly community-based sample in Kerala, India. Natl Med J India. 2000 Jan-Feb; 13(1):9-15. PMID: 10743369

Narula J, Malhotra A, Yasuda T, Talwar KK, Reddy KS, Chopra P, Southern JF, Vasan RS, Tandon R, Bhatia ML, Khaw BA, Strauss HW. Usefulness of antimyosin antibody imaging for the detection of active rheumatic myocarditis. Am J Cardiol. 1999 Oct 15; 84(8):946-50, A7. PMID: 10532521

Chadha SL, Vasan RS, Sarma PS, Shekhawat S, Tandon R, Gopinath N. Age- and height-specific reference limits of blood pressure of Indian children. Natl Med J India. 1999 Jul-Aug; 12(4):150-6. PMID: 10573968

Vasan RS, Larson MG, Benjamin EJ, Evans JC, Reiss CK, Levy D. Congestive heart failure in subjects with normal versus reduced left ventricular ejection fraction: prevalence and mortality in a population-based cohort. J Am Coll Cardiol. 1999 Jun; 33(7):1948-55.View Related Profiles.

Benjamin, Emelia
Larson, Martin
Ramachandran, Vasan

PMID: 10362198

Gopalakrishnan P, Vasan RS, Sarma PS, Nair KS, Thankappan KR. Prevalence of dental fluorosis and associated risk factors in Alappuzha district, Kerala. Natl Med J India. 1999 May-Jun; 12(3):99-103. PMID: 10492580

Vasan RS. Is a 'lot' necessarily better than a 'little'? Impact of aggressive cardiac revascularization strategies. Natl Med J India. 1998; 11:18-19.

Vasan RS, Larson MG, Levy D, Evans JC, Benjamin EJ. Distribution and categorization of echocardiographic measurements in relation to reference limits: the Framingham Heart Study: formulation of a height- and sex-specific classification and its prospective validation. Circulation. 1997 Sep 16; 96(6):1863-73.View Related Profiles.

Benjamin, Emelia
Larson, Martin
Ramachandran, Vasan

PMID: 9323074

Vasan RS, Larson MG, Benjamin EJ, Evans JC, Levy D. Left ventricular dilatation and the risk of congestive heart failure in people without myocardial infarction. N Engl J Med. 1997 May 8; 336(19):1350-5.View Related Profiles.

Benjamin, Emelia
Larson, Martin
Ramachandran, Vasan

PMID: 9134875

Vasan RS. Community health workers and tuberculosis control. Natl Med J India. 1997; 10:283-284.

Vasan RS, Shrivastava S, Vijayakumar M, Narang R, Lister BC, Narula J. Echocardiographic evaluation of patients with acute rheumatic fever and rheumatic carditis. Circulation. 1996 Jul 1; 94(1):73-82. PMID: 8964121

Levy D, Larson MG, Vasan RS, Kannel WB, Ho KK. The progression from hypertension to congestive heart failure. JAMA. 1996 May 22-29; 275(20):1557-62.View Related Profiles.

Larson, Martin
Ramachandran, Vasan

PMID: 8622246

Lindpaintner K, Lee M, Larson MG, Rao VS, Pfeffer MA, Ordovas JM, Schaefer EJ, Wilson AF, Wilson PW, Vasan RS, Myers RH, Levy D. Absence of association or genetic linkage between the angiotensin-converting-enzyme gene and left ventricular mass. N Engl J Med. 1996 Apr 18; 334(16):1023-8.View Related Profiles.

Larson, Martin
Myers, Richard
Ramachandran, Vasan

PMID: 8598840

Vasan RS, Benjamin EJ, Levy D. Congestive heart failure with normal left ventricular systolic function. Clinical approaches to the diagnosis and treatment of diastolic heart failure. Arch Intern Med. 1996;156:146-157. Congestive heart failure with normal left ventricular systolic function. Clinical approaches to the diagnosis and treatment of diastolic heart failure. Arch Intern Med. 1996; 156:146-157.
Vasan RS, Levy D. The role of hypertension in the pathogenesis of heart failure. A clinical mechanistic overview. Arch Intern Med. 1996; 156:1789-1796.
Vasan RS, Larson MG, Benjamin EJ, Levy D. Echocardiographic reference values for aortic root size: the Framingham Heart Study. J Am Soc Echocardiogr. 1995; 8:793-800.
Vasan RS, Benjamin EJ, Levy D. Prevalence, clinical features and prognosis of diastolic heart failure: an epidemiologic perspective. J Am Coll Cardiol. 1995; 26:1565-1574.
Vasan RS, Larson MG, Levy D. Determinants of echocardiographic aortic root size. The Framingham Heart Study. Circulation. 1995; 91:734-740.

Narula J, Chopra P, Talwar KK, Reddy KS, Vasan RS, Tandon R, Bhatia ML, Southern JF. Does endomyocardial biopsy aid in the diagnosis of active rheumatic carditis? Circulation. 1993 Nov; 88(5 Pt 1):2198-205. PMID: 8222115

Talwar KK, Vasan RS, Sharma S, Chopra P, Shrivastava S, Malhotra A. Non-specific aortoarteritis: long-term follow-up on immunosuppressive therapy. Int J Cardiol. 1993 Apr; 39(1):79-84. PMID: 8407011

Vasan RS, Shrivastava S, Kumar AS. The atrial septum after balloon mitral valvotomy: observations during surgery. Am Heart J. 1993 Feb; 125(2 Pt 1):549-50. PMID: 8427160

Vasan RS, Shrivastava S, Kumar MV. Value and limitations of Doppler echocardiographic determination of mitral valve area in Lutembacher syndrome. J Am Coll Cardiol. 1992 Nov 15; 20(6):1362-70. PMID: 1430687

Bahl VK, Aradhye S, Vasan RS, Malhotra A, Reddy KS, Malaviya AN. Myocardial systolic function in systemic lupus erythematosus: a study based on radionuclide ventriculography. Clin Cardiol. 1992 Jun; 15(6):433-5. PMID: 1617823

Vasan RS, Kaul U, Sanghvi S, Kamlakar T, Negi PC, Shrivastava S, Rajani M, Venugopal P, Wasir HS. Thrombolytic therapy for prosthetic valve thrombosis: a study based on serial Doppler echocardiographic evaluation. Am Heart J. 1992 Jun; 123(6):1575-80. PMID: 1595538

Bahl VK, Vasan RS, Jain P, Shrivastava S. Spectrum of right-sided infective endocarditis: an Indian experience. Int J Cardiol. 1992 May; 35(2):187-93. PMID: 1572739

Bahl VK, Vasan RS, Malhotra A, Wasir HS. A comparison of dobutamine infusion and exercise during radionuclide ventriculography in the evaluation of coronary arterial disease. Int J Cardiol. 1992 Apr; 35(1):49-55. PMID: 1563879

Vasan RS. On measuring "agreement" and not "correlation". J Am Coll Cardiol. 1992; 20:750.
Vasan RS. Estrogen replacement therapy and risk of breast cancer: results of two meta-analyses. Arch Intern Med. 1992; 152(1992):1090-1093.
Vasan RS. On being fair to the pulmonary artery catheter. Chest. 1992; 101:589-590.
Vasan RS. Lowering cholesterol and death due to accidents, suicides: unresolved issues. Arch Intern Med. 1992; 152:414-417.

Vasan RS, Shrivastava S, Dev V. Unusual electrocardiographic response during pulmonary balloon valvoplasty. Int J Cardiol. 1991 Dec; 33(3):442-4. PMID: 1761343

Bahl VK, Vasan RS, Aradhye S, Malaviya AN. Prevalence of cardiac abnormalities early in the course of systemic lupus erythematosus. Am J Cardiol. 1991 Dec 1; 68(15):1540-1. PMID: 1746443

Vasan RS, Narula J. Hypertension to normotension? A case of 'summer-salt'. Int J Cardiol. 1991 Oct; 33(1):179-80. PMID: 1937978

Shrivastava S, Dev V, Vasan RS, Das GS, Rajani M. Percutaneous balloon mitral valvuloplasty in juvenile rheumatic mitral stenosis. Am J Cardiol. 1991 Apr 15; 67(9):892-4. PMID: 2011991

Vasan RS, Prakash GS. To believe or not to believe. Int J Cardiol. 1991 Apr; 31(1):119-21. PMID: 2071245

Vasan RS. Cholesterol reduction and total mortality. Circulation. 1991; 84:2604.
Vasan RS. Reduced Fibrillin - the basic defect in Marfan syndrome. National Medical Journal of India. 1991; 4(5):262.
Vasan RS. Hypertrophic cardiomyopathy: disorder to be rechristened?. Int J Cardiol. 1991; 32:413-414.

Agarwal R, Kaul U, Vasan RS. Significance of Holter monitoring detected ischaemic changes before and shortly after successful coronary angioplasty. Indian Heart J. 1990 Sep-Oct; 42(5):381-3. PMID: 2086445

Vasan RS, Mehra NK, Malaviya AN, Chaudhuri TK. Lymphocytotoxic antibodies in patients with systemic lupus erythematosus & their household contacts. Indian J Med Res. 1990; 92:147-150.

Vasan RS, Bahl VK, Rajani M. Myocardial infarction associated with a myocardial bridge. Int J Cardiol. 1989 Nov; 25(2):240-1. PMID: 2807614

Vasan RS, Seshadri S, Narula J. Atrial natriuretic peptide: an atavistic hormone? Int J Cardiol. 1989 Mar; 22(3):407-8.View Related Profiles.

Seshadri, Sudha
Ramachandran, Vasan

PMID: 2523362

Agarwal R, Vasan RS, Singh RR, Saxena SP, Bhadoria DP, Srivastava AK, Verma A, Tiwari SC, Malaviya AN. Trigeminal and peripheral neuropathy in a patient with systemic sclerosis and silicosis. Clin Exp Rheumatol. 1987 Oct-Dec; 5(4):375-6. PMID: 2831000

Vasan RS, Choudhuri G, Tandon RK. Muscle biopsy in the evaluation of pyrexia of unknown origin (PUO). J Assoc Physicians India. 1986 Sep; 34(9):659-60. PMID: 2878915

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 821 publications over 37 distinct years, with a maximum of 76 publications in 2016

Bar chart showing 821 publications over 37 distinct years, with a maximum of 76 publications in 2016

Year	Publications
1986	1
1987	1
1989	2
1990	2
1991	8
1992	9
1993	3
1995	3
1996	5
1997	3
1998	1
1999	4
2000	5
2001	5
2002	12
2003	21
2004	30
2005	26
2006	26
2007	54
2008	51
2009	60
2010	62
2011	53
2012	35
2013	55
2014	55
2015	55
2016	76
2017	59
2018	6
2019	1
2020	6
2021	6
2022	7
2023	3
2024	10

Media Mentions

AHA News: Decades-Long Heart Study Shows Longer Lives, Lower Cardiovascular Risks

Health Day 4/18/2022

GRACE Score Overestimates Risk in Ethnic Minorities With NSTEMI

Medscape 2/28/2022

Framingham Heart Study to resume in-person examinations next week

Milford Daily News 9/8/2020

What Happens When Hearts Attack

Discover Magazine 6/16/2020

Framingham’s Family Tradition: Generations Help Researchers Unlock Medical Mysteries

WGBH 6/17/2019

Q&A: What’s driving health issues in rural America?

STAT 5/28/2019

Framingham Heart Study Inspires Researchers to Hit the Road

BU Today 5/28/2019

Framingham Heart Study Eyes Fourth Generation, Bolstered By New $38M

Worcester Business Journal 4/29/2019

Movers & Shakers

Daily Herald 4/28/2019

CVD Risk Similar in Men, Women With Diabetes, but Care Differs

Medscape 4/20/2019

Framingham Heart Study awarded $38 million to continue research

WCVB 4/17/2019

Framingham Heart Study awarded $38 million to continue research

MetroWest Daily News 4/17/2019

Framingham Heart Study awarded $38 million to continue research

Worcester Telegram 4/17/2019

For its next phase, the Framingham Heart Study will explore the biology of aging

STAT 4/17/2019

Framingham Heart Study lands $38M federal financing

Worcester Business Journal 4/17/2019

Framingham Heart Study Will Examine Aging with New $38M Funding

BU Today 4/17/2019

New research grant will enable Framingham Heart Study to explore biology of aging

The Boston Globe 4/16/2019

High BP in Young Adults a Harbinger of Premature CVD, Death

Medscape 11/13/2018

High blood pressure before age 40 linked to earlier strokes, heart disease

Reuters 11/8/2018

High BP in Early Adulthood Linked to Increased CVD Risk

MedPage Today 11/6/2018

Up All Night

BBC 10/31/2018

Framingham Heart Study marks 70 years, three generations of participants

The Boston Globe 10/30/2018

FRAMINGHAM HEART STUDY: Pioneering Work Led To Common Advice For Health Living

Milford Daily News 10/28/2018

7 Decades Of Breakthroughs At Framingham Heart Study

WCVB 10/26/2018

Framingham Heart Study: Technological Advances Spurred Deeper Understanding Of Heart Disease, Stroke

MetroWest Daily News 10/21/2018

70 Years Of The Framingham Heart Study

WGBH 10/12/2018

Framingham Heart Study Marks 70th Anniversary

WBUR 10/11/2018

The Study and Town That Changed the Health of a Generation

HealthDay 10/10/2018

2021 Association of American Physicians: Member

2021 McGill University, Canada: Louis and Artur Lucian Award for Research in Circulatory Disease

2021 American Heart Association: Distinguished Scientist Award

2020 Stiftung Charite, Charite Hospital, Berlin, Germany: Berlin Institute of Health Visiting Professor

2019 American Heart Association: William B Kannel MD, Lecturer

2016 Boston University School of Medicine: Jay and Louise Coffman Endowed Chair of Vascular Medicine

2016 Functional Genomics, and Translational Biology Council, AHA: Medal of Honor

2014 American Heart Association: Population Science Award

2012 American Heart Association: Mentoring Award

2010 Boston University School of Medicine: Evan's Scholar Award

2010 Boston University School of Medicine: Outstanding Mentor Award

In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Biomarkers
Cardiovascular Epidemiology
Echocardiography
Genetics Studies
High Blood Pressure
Risk Prediction
Disparities, Health Status
Rural Communities
Proteomics
Metabolomics
Microbiome, Gut
Social Determinants of Health
Risk Assessment
Vascular Function
Arterial Stiffness
Mentor

I am a trained mentor who values mentoring and mentorship as foundational aspects of careers. I have mentored over 75 scholars over the last 25 years (approximately 2-3 fellows every year). Of note, these mentees have differed in terms of their background as well as their research interest. They include medical students, interns, physician scientists, fellows post-internal medicine residency, cardiology fellows, and senior physicians. Roughly, 40% of my mentees have been women and a quarter are non-White. I directed the Framingham Heart Study fellowship program for nearly two decades. Recently, I am the Principal Investigator of a post-doctoral training program in cardiovascular epidemiology and an R38 (StARR) program for training medical residents at BUMC. I have received mentoring awards from the Department of Medicine and the AHA.
For each of these mentees, I modified my supervision according to their level of prior training and helped them select projects consistent and commensurate with their interest.
During the ‘exploratory’ stage of the mentorship, I meet with potential mentees (2-3 meetings over a 2-week period) to discuss my research areas, prior and ongoing research. I look for a commitment to research and professional growth, ambition, confidence, and a ‘matching’ of research interests when I evaluate potential mentees. If there is mutual interest in entering into a mentoring relation, I hold additional meetings (3-4 meetings over 3 weeks) with mentees to ‘initiate’ the mentoring process.
During this ‘initiation’ phase, I establish mutual goals and objectives of the mentoring relation, define mutual responsibilities, discuss preferred communication patterns (including frequency and methods) and forms of periodic evaluations, and formulate a ‘timeline’ for achievement of established goals. I discuss authorship rights, coauthorships, journal citations, plagiarism, responsible conduct of research, rigor and reproducibility in research, ethical issues, IRB clearance and formalize a written memorandum of understanding (mentoring map) regarding guidelines followed when projects are not completed within a year after fellowship. My mentees complete a needs identification grid and an individualized development plan (IDP) that we jointly review every quarter. I assist them in finding peer mentors, additional career mentors, and build a ‘mentor map.’ We discuss building foundational skills, professional skills and superordinate skills during their training period.
Thereafter, in the early phase of mentoring, I establish priorities and delineate tasks and discuss issues of authorship. I identify co-mentors to ensure complementary guidance in areas where my expertise is limited.
The ‘working’ phase of mentorship for fellows is aimed at helping mentees choose research areas and topics commensurate with their prior level of training, areas of interest and future career goals. I try my best to give fellows the opportunity of working on at least one project that uses a cross-sectional design and another that uses longitudinal data so that they gain instruction in both regression and survival analyses.
Besides serving as a research guide, I try my best to serve as an advisor and a sponsor for mentees. I strive to be readily available to trainees for discussions, for ventilating their complaints, and for sharing their frustrations and joys alike; to maintain a learning atmosphere that fosters open, honest and empathic communication; to provide constant feedback and encouragement to mentees; to promote efficient time management, and to enable mentees to establish a research focus/niche; and above all, to emphasize the professional values of integrity, honesty and accountability. I also guide mentees in career planning, career progression, striking a professional and personal (work-life) balance, time management, and working towards an appropriate combination of research, teaching and clinical care.

Available to Mentor as: (Review Mentor Role Definitions):