Vasan S. Ramachandran, MD
Professor
Boston University School of Medicine
Dept of Medicine
Preventive Medicine & Epidemiology

MD, All India Institute of Medical Science (AIIMS)
MBBS, All India Institute of Medical Science (AIIMS)
DM, All India Institute of Medical Science (AIIMS)



Vasan S. Ramachandran, M.D., Principal Investigator and Director of the FHS, and Director of the FHS fellowship program in cardiovascular epidemiology for the last 25 years.

Dr. Ramachandran is a Professor of Medicine and Epidemiology at BUSM/BUSPH, and Chief, Section of Preventive Medicine and Epidemiology, Department of Medicine, BUSM. He is the Jay & Louis Coffman Professor of Vascular Medicine at BUSM. Dr. Ramachandran is a trained cardiologist with subspecialty training in echocardiography. He is a fellow of the AHA Councils on Epidemiology and Prevention and Functional Genomics and Translational Biology, and a fellow of the American College of Cardiology (ACC). He has extensive experience in supervising trainees at many levels and *teaches the foundational core course on Cardiovascular Epidemiology at BUSPH (EP751) that all trainees of this program will take*. He has several active R01 grants from the NHLBI/NIDDK and received two K24 Mid-Career Investigator mentoring grants from the NHLBI. He has mentored several K23 awardees, and is currently the primary mentor for four K23 awardees and a K99R00 grantee (junior faculty mentors-in-training in this program). Overall, he has supervised over 60 trainees during the past 20 years; most are in key positions in academia. He received the Outstanding Mentor awards from the Department of Medicine, BUSM, and the AHA Council on Epidemiology and Prevention, and the prestigious AHA Population Science
Award in 2014.

Importantly, Dr. Ramachandran’s own peer-reviewed funding spans thematic areas of genetics and genomics, cardiac and vascular remodeling, novel biomarkers, systems biology including proteomics and metabolomics, and stem cell biology. He has a 25-year history in research in cardiovascular epidemiology, including the two years he trained as a FHS fellow (1993-1995). He established the first School of Public Health in India between 1996-1998, serving as its inaugural director and the coordinator of its MPH program. He is the founding member and leader of the international EchoGen consortium, and chairs the Steering Committee of the Chronic Kidney Disease Biomarker Consortium funded by the NIDDK (U01DK085689). He is recognized internationally for translational research in cardiovascular epidemiology and lectures regularly at the AHA early career session on “how to develop a career in translational research and epidemiology/genetics.” He is well equipped to mentor trainees about grant writing having been a member of the Cardiovascular and Sleep (CASE) SRG, and an active reviewer of grants for national and international funding agencies. He served for many years on the NHLBI panel for reviewing K23-K24-K25 career development grants. He is well qualified to mentor trainees in best publication practices and has served until recently as an Associate Editor for *Circulation*, and the Editor-in-Chief of *Circulation: Cardiovascular Genetics*. He works collaboratively with the Center for Translational Epidemiology and Comparative Effectiveness Research within the Department of Medicine, BUSM, that hosts multiple epidemiological datasets, including from multiple cohort studies, national surveys (NHANES), administrative databases and electronic health records; this center will be a valuable data source for trainees.

Section Chief
Boston University School of Medicine
Medicine
Preventive Medicine & Epidemiology

Jay & Louis Coffman Professor of Vascular Medicine
Boston University School of Medicine
Medicine


Director, Echocardiography/Vascular Laboratory
Framingham Heart Study


Mentor for Graduate Medical Students
Boston University School of Medicine, Division of Graduate Medical Sciences




Vascular Stiffness as a Precursor of Hypertension in a Middle-aged Cohort
08/01/2015 - 06/30/2018 (PI)
NIH/National Heart, Lung, and Blood Inst
5R01HL126136-02

Proteomic pathway discovery in Cardiovascular Disease
07/01/2016 - 04/30/2018 (PI)
Beth Israel Deaconess Medical Center, In NIH NHLBI
1R01HL132320-01

Multidisciplinary Training Program in Cardiovascular Epidemiology
04/01/2016 - 03/31/2018 (PI)
NIH/National Heart, Lung, and Blood Inst
3T32HL125232-01A1S1

Framingham Heart Study
09/25/2015 - 03/31/2018 (PI)
NIH/National Heart, Lung, and Blood Inst


Framingham Heart Study
05/07/2015 - 03/31/2018 (PI)
NIH/National Heart, Lung, and Blood Inst


Physical Activity, Cardiometabolic Risk, and Target-Organ Damage in Older Adults
07/15/2014 - 03/31/2018 (PI)
NIH/National Institute on Aging
5R01AG047645-02

Lipid Biomarkers for Diabetic Heart Disease
04/15/2012 - 02/28/2018 (PI)
Washington University NIH
4P20HL113444-05

Cardiac Microstructure and heart failure risk in the Community
04/01/2016 - 01/31/2018 (PI)
The Brigham and Women's Hospital, Inc. NIH NHLBI
5R01HL131532-02

Molecular and Genetic Epidimiology of Lipoprotein (a)-mediated Calcific Aortic Valve Disease
01/01/2017 - 12/31/2017 (PI)
McGill University Health Center NIH NHLBI
1R01HL128550-01A1

Clinical and genetic correlates of the gut microbiome, and relation to cardiometabolic risk
01/01/2016 - 12/31/2017 (PI)
Broad Institute, Inc., The NIH NHLBI
1R01HL131015-01

Showing 10 of 37 results. Show All Results

Population-Based Reference Ranges for Estradiol and Estrone in Men
04/07/2012 - 07/31/2012 (Activity-level PI)
PI: Shalender Bhasin, MBBS
NIH-NIDDK



Yr Title Project-Sub Proj Pubs
2017 Cardiometabolic Outcomes in Multi-ethnic Physical Activity & Sedentary Behavior Study (COMPASS) 1R01HL136266-01
2017 Multidisciplinary Training Program in Cardiovascular Epidemiology 5T32HL125232-02
2017 Multidisciplinary Training Program in Cardiovascular Epidemiology 3T32HL125232-01A1S1
2017 Comprehensive Metabolic Profiling of Exercise to Predict Cardiometabolic Risk 5R01HL131029-02 4
2017 Clinical, genetic and cardiometabolic risk correlates of the gut microbiome 5R01HL131015-02
2016 Proteomic Pathway Discovery in Cardiovascular Disease 1R01HL132320-01
2016 Multidisciplinary Training Program in Cardiovascular Epidemiology 1T32HL125232-01A1
2016 IGF::OT::IGF FRAMINGHAM HEART STUDY (FHS) - TASK ORDER 01 268201500001I-2-26800001-1
2016 Clinical, genetic and cardiometabolic risk correlates of the gut microbiome 1R01HL131015-01
2016 Comprehensive Metabolic Profiling of Exercise to Predict Cardiometabolic Risk 1R01HL131029-01 4
Showing 10 of 63 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Zakharov MN, Bhasin S, Travison TG, Xue R, Ulloor J, Ramachandran V, Carter E, Wu F, Jasuja R. Corrigendum to "A multi-step, allosteric model of testosterone''s binding to sex hormone binding globulin" [Mol. Cell. Endocrinol. 399 (2015) 190-200]. Mol Cell Endocrinol. 2017 Oct 15; 454:167.View Related Profiles. PMID: 28780939.
  2. Fetterman JL, Liu C, Mitchell GF, Ramachandran VS, Benjamin EJ, Vita JA, Hamburg NM, Levy D. Relations of mitochondrial genetic variants to measures of vascular function. Mitochondrion. 2017 Oct 07.View Related Profiles. PMID: 28993255.
  3. Vasan RS, Xanthakis V, Lyass A, Andersson C, Tsao C, Cheng S, Aragam J, Benjamin EJ, Larson MG. Epidemiology of Left Ventricular Systolic Dysfunction and Heart Failure in the Framingham Study: An Echocardiographic Study Over 3 Decades. JACC Cardiovasc Imaging. 2017 Sep 09.View Related Profiles. PMID: 28917679.
  4. Jasuja GK, Travison TG, Murabito JM, Davda MN, Rose AJ, Basaria S, Coviello A, Vasan RS, D''Agostino R, Bhasin S. Circulating Estrogen Levels and Self-Reported Health and Mobility Limitation in Community-Dwelling Men of the Framingham Heart Study. J Gerontol A Biol Sci Med Sci. 2017 Aug 01; 72(8):1137-1142.View Related Profiles. PMID: 28329787; DOI: 10.1093/gerona/glw197;.
  5. Niiranen TJ, McCabe EL, Larson MG, Henglin M, Lakdawala NK, Vasan RS, Cheng S. Risk for hypertension crosses generations in the community: a multi-generational cohort study. Eur Heart J. 2017 Aug 01; 38(29):2300-2308.View Related Profiles. PMID: 28430902; DOI: 10.1093/eurheartj/ehx134;.
  6. Tan ZS, Spartano NL, Beiser AS, DeCarli C, Auerbach SH, Vasan RS, Seshadri S. Physical Activity, Brain Volume, and Dementia Risk: The Framingham Study. J Gerontol A Biol Sci Med Sci. 2017 Jun 01; 72(6):789-795.View Related Profiles. PMID: 27422439; DOI: 10.1093/gerona/glw130;.
  7. Jensen MK, Jensen RA, Mukamal KJ, Guo X, Yao J, Sun Q, Cornelis M, Liu Y, Chen MH, Kizer JR, Djoussé L, Siscovick DS, Psaty BM, Zmuda JM, Rotter JI, Garcia M, Harris T, Chen I, Goodarzi MO, Nalls MA, Keller M, Arnold AM, Newman AB, Hoogeveen RC, Rexrode KM, Rimm EB, Hu FB, Ramachandran VS, Katz R, Pankow JS, Ix JH. Detection of genetic loci associated with plasma fetuin-A: a meta-analysis of genome-wide association studies from the CHARGE Consortium. Hum Mol Genet. 2017 Jun 01; 26(11):2156-2163. PMID: 28379451.
  8. Niiranen TJ, Lyass A, Larson MG, Hamburg NM, Benjamin EJ, Mitchell GF, Vasan RS. Prevalence, Correlates, and Prognosis of Healthy Vascular Aging in a Western Community-Dwelling Cohort: The Framingham Heart Study. Hypertension. 2017 Aug; 70(2):267-274.View Related Profiles. PMID: 28559398; DOI: 10.1161/HYPERTENSIONAHA.117.09026;.
  9. Tragante V, Gho JMIH, Felix JF, Vasan RS, Smith NL, Voight BF, Palmer C, van der Harst P, Moore JH, Asselbergs FW. Gene Set Enrichment Analyses: lessons learned from the heart failure phenotype. BioData Min. 2017; 10:18. PMID: 28559929; DOI: 10.1186/s13040-017-0137-5;.
  10. Niiranen TJ, McCabe EL, Larson MG, Henglin M, Lakdawala NK, Vasan RS, Cheng S. Heritability and risks associated with early onset hypertension: multigenerational, prospective analysis in the Framingham Heart Study. BMJ. 2017 May 12; 357:j1949.View Related Profiles. PMID: 28500036.
Showing 10 of 751 results. Show More