Edwin Van Den Heuvel | Profiles RNS

Edwin Van Den Heuvel, PhD

Adjunct Professor

Boston University Chobanian & Avedisian School of Medicine

Medicine

Preventive Medicine & Epidemiology

PhD, University of Amsterdam
MSc, University of Amsterdam

Websites

	ResearchGate
	Maelstrom Profile
	Google Scholar

ORCID : 0000-0001-9157-7224

Dr. Edwin van den Heuvel studied mathematics at the University of Amsterdam, where he also obtained his PhD in mathematical statistics. He has been working as a consultant on quality control and quality improvement, he has been a director of a statistical unit in a pharmaceutical company for more than eight years, and he has been a professor of medical statistics at the University of Groningen. He considers himself as an all-round research statistician with a broad range of expertise and he specializes in the analysis of complex structured data sets.

Professor
Boston University School of Public Health
Biostatistics

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Website Copy PMIDs To Clipboard

de Klerk ND, Berben PB, der Ven MV, Fransen AF, van der Hout-van der Jagt MB, Oei SG, van Laar JO, van den Heuvel ER. Optimizing clinical scientific research: the cohort intervention random sampling study with historical controls. J Comp Eff Res. 2025 Nov; 14(11):e240168. PMID: 40955624; PMCID: PMC12580914; DOI: 10.57264/cer-2024-0168;

Deneer R, Zhan Z, Van den Heuvel E, van Boxtel AG, Boer AK, van Riel NA, Scharnhorst V. A comparison of semi-parametric statistical modeling approaches to dynamic classification of irregularly and sparsely sampled curves. Stat Methods Med Res. 2025 Nov; 34(11):2202-2218. PMID: 40905767; PMCID: PMC12669398; DOI: 10.1177/09622802251374288;

Alexopoulos E, Walsh J, Hsu JY, Blaha MJ, Cheng S, Daubert MA, Dunn G, Durda P, Fox ER, Thomas Y, van den Heuvel E, Judd SE, Vasan RS, Douglas PS, Bloomfield GS. Valvular Heart Disease Associations with Cardiac Biomarkers Using AI-guided Echocardiography: the RURAL Cohort Study. medRxiv. 2025 Sep 02. PMID: 40950507; PMCID: PMC12425031; DOI: 10.1101/2025.08.27.25334591;

Berben PBQ, de Klerk ND, van der Ven M, Fransen AF, Niemarkt HJ, van den Heuvel ER, van der Hout-van der Jagt MB, Oei SG, van Laar JOEH. Non-invasive electrophysiological monitoring vs conventional monitoring during labour in a tertiary obstetric care centre in the Netherlands: study protocol of a cohort intervention random sampling study (NIEM-II study). BMJ Open. 2025 Jul 22; 15(7):e102901. PMID: 40701589; PMCID: PMC12306333; DOI: 10.1136/bmjopen-2025-102901;

van Tetering AAC, de Vries EL, Ntuyo P, van den Heuvel ER, Fransen AF, van der Hout-van der Jagt MB, Namagembe I, Byamugisha J, Oei SG. Mono-Professional Simulation-Based Obstetric Training in a Low-Resource Setting: Stepped-Wedge Cluster Randomized Trial. JMIR Med Educ. 2025 May 09; 11:e54911. PMID: 40344206; PMCID: PMC12083734; DOI: 10.2196/54911;

Huang C, Long X, van der Ven M, Kaptein M, Oei SG, van den Heuvel E. Predicting preterm birth using electronic medical records from multiple prenatal visits. BMC Pregnancy Childbirth. 2024 Dec 21; 24(1):843. PMID: 39709388; PMCID: PMC11662559; DOI: 10.1186/s12884-024-07049-y;

Griffith LE, Brini A, Muniz-Terrera G, St John PD, Stirland LE, Mayhew A, Oyarzún D, van den Heuvel E. A call for caution when using network methods to study multimorbidity: an illustration using data from the Canadian Longitudinal Study on Aging. J Clin Epidemiol. 2024 Aug; 172:111435. PMID: 38901709

Heidema S, Stoepker IV, Flaherty G, Angelo KM, Post RAJ, Miller C, Libman M, Hamer DH, van den Heuvel ER, Huits R. From GeoSentinel data to epidemiological insights: a multidisciplinary effort towards artificial intelligence-supported detection of infectious disease outbreaks. J Travel Med. 2024 Jun 03; 31(4).View Related Profiles.

Hamer, Davidson
Van Den Heuvel, Edwin

PMID: 38236181; PMCID: PMC11287261; DOI: 10.1093/jtm/taae013;

van den Berge BA, Groenhof F, Werker PMN, Furniss D, Kuo R, van den Heuvel ER, Broekstra DC. Mortality in patients with Dupuytren's disease in the first 5 years after diagnosis: a population-based survival analysis. J Hand Surg Eur Vol. 2024 Oct; 49(9):1110-1118. PMID: 38488516; PMCID: PMC11457468; DOI: 10.1177/17531934241235546;

Post RAJ, van den Heuvel ER, Putter H. Bias of the additive hazard model in the presence of causal effect heterogeneity. Lifetime Data Anal. 2024 Apr; 30(2):383-403. PMID: 38466520; PMCID: PMC10957647; DOI: 10.1007/s10985-024-09616-z;

Showing 10 of 222 results. Show More

van den Heuvel ER, Almalik O, Zhan Z. Simulation models for aggregated data meta-analysis: Evaluation of pooling effect sizes and publication biases. Stat Methods Med Res. 2024 Mar; 33(3):359-375. PMID: 38460950

Fazlalizadeh H, Khan MS, Fox ER, Douglas PS, Adams D, Blaha MJ, Daubert MA, Dunn G, van den Heuvel E, Kelsey MD, Martin RP, Thomas JD, Thomas Y, Judd SE, Vasan RS, Budoff MJ, Bloomfield GS. Closing the Last Mile Gap in Access to Multimodality Imaging in Rural Settings: Design of the Imaging Core of the Risk Underlying Rural Areas Longitudinal Study. Circ Cardiovasc Imaging. 2024 Feb; 17(2):e015496. PMID: 38377236; PMCID: PMC10883604; DOI: 10.1161/CIRCIMAGING.123.015496;

Post RAJ, van den Heuvel ER, Putter H. The built-in selection bias of hazard ratios formalized using structural causal models. Lifetime Data Anal. 2024 Apr; 30(2):404-438. PMID: 38358572; PMCID: PMC11300553; DOI: 10.1007/s10985-024-09617-y;

van den Berge BA, Omar FMA, Werker PMN, Zhan Z, van den Heuvel ER, Broekstra DC. Treatment Durability of Limited Fasciectomy versus Percutaneous Needle Fasciotomy for Dupuytren Disease. Plast Reconstr Surg. 2024 Nov 01; 154(5):928e-938e. PMID: 38289897; PMCID: PMC11512621; DOI: 10.1097/PRS.0000000000011322;

Mulders PJAM, van den Heuvel ER, Reidsma P, Duivesteijn W. Introducing exceptional growth mining-Analyzing the impact of soil characteristics on on-farm crop growth and yield variability. PLoS One. 2024; 19(1):e0296684. PMID: 38285649; PMCID: PMC10824435; DOI: 10.1371/journal.pone.0296684;

Andreacchi AT, Brini A, Van den Heuvel E, Muniz-Terrera G, Mayhew A, St John P, Stirland LE, Griffith LE. An Exploration of Methods to Resolve Inconsistent Self-Reporting of Chronic Conditions and Impact on Multimorbidity in the Canadian Longitudinal Study on Aging. J Aging Health. 2025 Jan; 37(1-2):40-53. PMID: 38016065; PMCID: PMC11566091; DOI: 10.1177/08982643231215476;

Post RAJ, Petkovic M, van den Heuvel IL, van den Heuvel ER. Flexible Machine Learning Estimation of Conditional Average Treatment Effects: A Blessing and a Curse. Epidemiology. 2024 Jan 01; 35(1):32-40. PMID: 37889951

Vasan RS, Rao S, van den Heuvel E. Race as a Component of Cardiovascular Disease Risk Prediction Algorithms. Curr Cardiol Rep. 2023 Oct; 25(10):1131-1138. PMID: 37581773

Bukkems LMP, van Dommelen L, Regis M, van den Heuvel E, Nieuwenhuizen L. The Use of Galactomannan Antigen Assays for the Diagnosis of Invasive Pulmonary Aspergillosis in the Hematological Patient: A Systematic Review and Meta-Analysis. J Fungi (Basel). 2023 Jun 15; 9(6). PMID: 37367610; PMCID: PMC10305130; DOI: 10.3390/jof9060674;

Molenaar CJL, Minnella EM, Coca-Martinez M, Ten Cate DWG, Regis M, Awasthi R, Martínez-Palli G, López-Baamonde M, Sebio-Garcia R, Feo CV, van Rooijen SJ, Schreinemakers JMJ, Bojesen RD, Gögenur I, van den Heuvel ER, Carli F, Slooter GD. Effect of Multimodal Prehabilitation on Reducing Postoperative Complications and Enhancing Functional Capacity Following Colorectal Cancer Surgery: The PREHAB Randomized Clinical Trial. JAMA Surg. 2023 Jun 01; 158(6):572-581. PMID: 36988937; PMCID: PMC10061316; DOI: 10.1001/jamasurg.2023.0198;

Kouris PD, Brini A, Schepers E, Boot MD, Van Den Heuvel ER, Hensen EJM. Optimizing Catalytic Depolymerization of Lignin in Ethanol with a Day-Clustered Box-Behnken Design. Ind Eng Chem Res. 2023 May 10; 62(18):6874-6885. PMID: 37284245; PMCID: PMC10241191; DOI: 10.1021/acs.iecr.2c03618;

Vermeer J, Vinck T, de Louw B, Slingerland S, van 't Veer M, Regis M, Jansen JM, van den Heuvel E, Dekker L. Improving outcomes of AF ablation by integrated personalized lifestyle interventions: rationale and design of the prevention to improve outcomes of PVI (POP) trial. Clin Res Cardiol. 2023 Jun; 112(6):716-723. PMID: 37000245; PMCID: PMC10241695; DOI: 10.1007/s00392-023-02185-5;

van den Broek JM, Heydari S, Zhan Z, van 't Veer M, Sammali F, Overeem S, van den Heuvel ER, Dekker LR. Can body position be arrhythmogenic? Sleep Med. 2023 May; 105:21-24. PMID: 36940516

Veringa A, Brüggemann RJ, Span LFR, Biemond BJ, de Boer MGJ, van den Heuvel ER, Klein SK, Kraemer D, Minnema MC, Prakken NHJ, Rijnders BJA, Swen JJ, Verweij PE, Wondergem MJ, Ypma PF, Blijlevens N, Kosterink JGW, van der Werf TS, Alffenaar JC. Therapeutic drug monitoring-guided treatment versus standard dosing of voriconazole for invasive aspergillosis in haematological patients: a multicentre, prospective, cluster randomised, crossover clinical trial. Int J Antimicrob Agents. 2023 Feb; 61(2):106711. PMID: 36642232

Griffith LE, McMillan J, Hogan DB, Pourfarzaneh S, Anderson LN, Kirkland S, Basta NE, van den Heuvel E, Raina P. Frailty and the impacts of the COVID-19 pandemic on community-living middle-aged and older adults: an analysis of data from the Canadian Longitudinal Study on Aging (CLSA). Age Ageing. 2022 Dec 05; 51(12). PMID: 36571783; PMCID: PMC9792085; DOI: 10.1093/ageing/afac289;

Zhan Z, de Bock GH, van den Heuvel ER. Comparison of analysis methods and design choices for treatment-by-period interaction in unidirectional switch designs: a simulation study. BMC Med Res Methodol. 2022 Nov 17; 22(1):294. PMID: 36396984; PMCID: PMC9673415; DOI: 10.1186/s12874-022-01765-9;

Noben L, Lempersz C, van den Heuvel ER, Zhan Z, Vandenbussche FPHA, Coumans ABC, Haak MC, Vullings R, Oei SG, Clur SAB, van Laar JOEH. The electrical heart axis in fetuses with congenital heart disease, measured with non-invasive fetal electrocardiography. PLoS One. 2022; 17(10):e0275802. PMID: 36264863; PMCID: PMC9584524; DOI: 10.1371/journal.pone.0275802;

Vasan RS, Song RJ, van den Heuvel ER. Temporal Trends in Incidence of Premature Cardiovascular Disease Over the Past 7 Decades: The Framingham Heart Study. J Am Heart Assoc. 2022 Oct 04; 11(19):e026497. PMID: 36172970; PMCID: PMC9673696; DOI: 10.1161/JAHA.122.026497;

IJzerman-Boon PC, Manju MA, van den Heuvel ER. Non-inferiority testing for qualitative microbiological methods: Assessing and improving the approach in USP 1223. J Biopharm Stat. 2022 Nov 02; 32(6):915-941. PMID: 36131516

Scholten AWJ, Zhan Z, Niemarkt HJ, Vervoorn M, van Leuteren RW, de Jongh FH, van Kaam AH, van den Heuvel ER, Hutten GJ. Multicentre paired non-inferiority study of the cardiorespiratory monitoring performance of the wireless and non-adhesive Bambi® belt measuring diaphragm activity in neonates: study protocol. BMJ Paediatr Open. 2022 Jun; 6(1). PMID: 36053638; PMCID: PMC9185582; DOI: 10.1136/bmjpo-2022-001430;

Broekstra DC, Lanting R, Werker PMN, van den Heuvel ER. Disease Course of Primary Dupuytren Disease: 5-Year Results of a Prospective Cohort Study. Plast Reconstr Surg. 2022 Jun 01; 149(6):1371-1378. PMID: 35404338

van Oostrum NHM, de Vet CM, Clur SB, van der Woude DAA, van den Heuvel ER, Oei SG, van Laar JOEH. Fetal myocardial deformation measured with two-dimensional speckle-tracking echocardiography: longitudinal prospective cohort study of 124 healthy fetuses. Ultrasound Obstet Gynecol. 2022 May; 59(5):651-659. PMID: 34558747; PMCID: PMC9321172; DOI: 10.1002/uog.24781;

Ungolo F, van den Heuvel ER. Inference on latent factor models for informative censoring. Stat Methods Med Res. 2022 May; 31(5):801-820. PMID: 35077263; PMCID: PMC9014689; DOI: 10.1177/09622802211057290;

Vasan RS, van den Heuvel E. Differences in estimates for 10-year risk of cardiovascular disease in Black versus White individuals with identical risk factor profiles using pooled cohort equations: an in silico cohort study. Lancet Digit Health. 2022 01; 4(1):e55-e63.View Related Profiles.

Van Den Heuvel, Edwin
Ramachandran, Vasan

PMID: 34952676; PMCID: PMC8715354; DOI: 10.1016/S2589-7500(21)00236-3;

Lempersz C, Noben L, Clur SB, van den Heuvel E, Zhan Z, Haak M, Oei SG, Vullings R, van Laar JOEH. The electrical heart axis of the fetus between 18 and 24 weeks of gestation: A cohort study. PLoS One. 2021; 16(12):e0256115. PMID: 34914710; PMCID: PMC8675734; DOI: 10.1371/journal.pone.0256115;

P Den Teuling NG, van den Heuvel ER, Aloia MS, Pauws SC. A latent-class heteroskedastic hurdle trajectory model: patterns of adherence in obstructive sleep apnea patients on CPAP therapy. BMC Med Res Methodol. 2021 12 01; 21(1):269. PMID: 34852769; PMCID: PMC8638441; DOI: 10.1186/s12874-021-01407-6;

Griffith LE, Raina P, Kanters D, Hogan D, Patterson C, Papaioannou A, Richardson J, Gilsing A, Thompson M, van den Heuvel E. Frailty differences across population characteristics associated with health inequality: a cross-sectional analysis of baseline data from the Canadian Longitudinal Study on Aging (CLSA). BMJ Open. 2021 07 19; 11(7):e047945. PMID: 34281924; PMCID: PMC8291332; DOI: 10.1136/bmjopen-2020-047945;

Almalik O, Zhan Z, van den Heuvel ER. Tests for publication bias are unreliable in case of heteroscedasticity. Contemp Clin Trials Commun. 2021 Jun; 22:100781. PMID: 34179565; PMCID: PMC8209747; DOI: 10.1016/j.conctc.2021.100781;

Brini A, Avagyan V, de Vos RCH, Vossen JH, van den Heuvel ER, Engel J. Improved One-Class Modeling of High-Dimensional Metabolomics Data via Eigenvalue-Shrinkage. Metabolites. 2021 Apr 13; 11(4). PMID: 33924479; PMCID: PMC8069634; DOI: 10.3390/metabo11040237;

Frenken MWE, Thijssen KMJ, Vlemminx MWC, van den Heuvel ER, Westerhuis MEMH, Oei SG. Clinical evaluation of electrohysterography as method of monitoring uterine contractions during labor: A propensity score matched study. Eur J Obstet Gynecol Reprod Biol. 2021 Apr; 259:178-184. PMID: 33684672

Post RAJ, Regis M, Zhan Z, van den Heuvel ER. How did governmental interventions affect the spread of COVID-19 in European countries? BMC Public Health. 2021 02 26; 21(1):411. PMID: 33637062; PMCID: PMC7908011; DOI: 10.1186/s12889-021-10257-2;

Moors S, Joshi R, Bullens LM, van Oostrum NHM, Regis M, van den Heuvel ER, Oei SG, van Laar JOEH, van der Hout-van der Jagt MB. A randomized controlled trial studying the effect of maternal hyperoxygenation on fetal heart rate in suspected fetal distress. Physiol Meas. 2020 12 11; 41(11):115002. PMID: 33049730

Khinda J, Janjua NZ, Cheng S, van den Heuvel ER, Bhatti P, Darvishian M. Association between markers of immune response at hospital admission and COVID-19 disease severity and mortality: A meta-analysis and meta-regression. J Med Virol. 2021 02; 93(2):1078-1098. PMID: 32776551; PMCID: PMC7436507; DOI: 10.1002/jmv.26411;

de Leeuw FA, van de Rest O, Doorduijn AS, Fieldhouse JLP, de van der Schueren MAE, Visser M, van den Heuvel EGHM, Scheltens P, Teunissen CE, Kester MI, van der Flier WM. Associations Between Nutrient Intake and Corresponding Nutritional Biomarker Levels in Blood in a Memory Clinic Cohort: The NUDAD Project. J Am Med Dir Assoc. 2020 10; 21(10):1436-1438. PMID: 32641272

Schwedhelm E, Song RJ, Vasan RS, van den Heuvel ER, Hannemann J, Xanthakis V, Böger R. Association of Lower Plasma Homoarginine Concentrations with Greater Risk of All-Cause Mortality in the Community: The Framingham Offspring Study. J Clin Med. 2020 Jun 26; 9(6).View Related Profiles.

Van Den Heuvel, Edwin
Xanthakis, Vanessa

PMID: 32604958; PMCID: PMC7356383; DOI: 10.3390/jcm9062016;

de Zwart AES, Riezebos-Brilman A, Alffenaar JC, van den Heuvel ER, Gan CT, van der Bij W, Kerstjens HAM, Verschuuren EAM. Evaluation of 10 years of parainfluenza virus, human metapneumovirus, and respiratory syncytial virus infections in lung transplant recipients. Am J Transplant. 2020 12; 20(12):3529-3537. PMID: 32449200; PMCID: PMC7754441; DOI: 10.1111/ajt.16073;

van den Heuvel EPJ, Tauris TM. Comment on "A noninteracting low-mass black hole-giant star binary system". Science. 2020 05 08; 368(6491). PMID: 32381688; DOI: 10.1126/science.aba3282;

Jentsch MC, Burger H, Meddens MBM, Beijers L, van den Heuvel ER, Meddens MJM, Schoevers RA. Gender Differences in Developing Biomarker-Based Major Depressive Disorder Diagnostics. Int J Mol Sci. 2020 Apr 25; 21(9). PMID: 32344909; PMCID: PMC7246841; DOI: 10.3390/ijms21093039;

Zhan Z, van den Heuvel ER. Correction for "Optimal unidirectional switch designs" by Zhuozhao Zhan, Geertruida H. de Bock, and Edwin R. van den Heuvel. Stat Med. 2020 08 30; 39(19):2587. PMID: 32323336

Moors S, Bullens LM, van Runnard Heimel PJ, Dieleman JP, Kulik W, Bakkeren DL, van den Heuvel ER, van der Hout-van der Jagt MB, Oei SG. The effect of intrauterine resuscitation by maternal hyperoxygenation on perinatal and maternal outcome: a randomized controlled trial. Am J Obstet Gynecol MFM. 2020 05; 2(2):100102. PMID: 33345953

Verbeek HH, de Groot JWB, Sluiter WJ, Muller Kobold AC, van den Heuvel ER, Plukker JT, Links TP. Calcitonin testing for detection of medullary thyroid cancer in people with thyroid nodules. Cochrane Database Syst Rev. 2020 03 16; 3:CD010159. PMID: 32176812; PMCID: PMC7075519; DOI: 10.1002/14651858.CD010159.pub2;

Raina P, Gilsing A, Mayhew AJ, Sohel N, van den Heuvel E, Griffith LE. Individual and population level impact of chronic conditions on functional disability in older adults. PLoS One. 2020; 15(2):e0229160. PMID: 32078637; PMCID: PMC7032687; DOI: 10.1371/journal.pone.0229160;

de Leeuw FA, van der Flier WM, Tijms BM, Scheltens P, Mendes VM, Manadas B, Bierau J, van Wijk N, van den Heuvel EGHM, Mohajeri MH, Teunissen CE, Kester MI. Specific Nutritional Biomarker Profiles in Mild Cognitive Impairment and Subjective Cognitive Decline Are Associated With Clinical Progression: The NUDAD Project. J Am Med Dir Assoc. 2020 10; 21(10):1513.e1-1513.e17. PMID: 32001171

van Klarenbosch J, van den Heuvel ER, van Oeveren W, de Vries AJ. Does Intraoperative Cell Salvage Reduce Postoperative Infection Rates in Cardiac Surgery? J Cardiothorac Vasc Anesth. 2020 Jun; 34(6):1457-1463. PMID: 32144053

Dekker LH, Vinke PC, Riphagen IJ, Minovic I, Eggersdorfer ML, van den Heuvel EGHM, Schurgers LJ, Kema IP, Bakker SJL, Navis G. Cheese and Healthy Diet: Associations With Incident Cardio-Metabolic Diseases and All-Cause Mortality in the General Population. Front Nutr. 2019; 6:185. PMID: 31921878; PMCID: PMC6927928; DOI: 10.3389/fnut.2019.00185;

Raina P, Wolfson C, Kirkland S, Griffith LE, Balion C, Cossette B, Dionne I, Hofer S, Hogan D, van den Heuvel ER, Liu-Ambrose T, Menec V, Mugford G, Patterson C, Payette H, Richards B, Shannon H, Sheets D, Taler V, Thompson M, Tuokko H, Wister A, Wu C, Young L. Corrigendum to: Cohort Profile: The Canadian Longitudinal Study on Aging (CLSA). Int J Epidemiol. 2019 12 01; 48(6):2066. PMID: 31605135; PMCID: PMC6929521; DOI: 10.1093/ije/dyz221;

Raina P, Wolfson C, Kirkland S, Griffith LE, Balion C, Cossette B, Dionne I, Hofer S, Hogan D, van den Heuvel ER, Liu-Ambrose T, Menec V, Mugford G, Patterson C, Payette H, Richards B, Shannon H, Sheets D, Taler V, Thompson M, Tuokko H, Wister A, Wu C, Young L. Cohort Profile: The Canadian Longitudinal Study on Aging (CLSA). Int J Epidemiol. 2019 12 01; 48(6):1752-1753j. PMID: 31633757; PMCID: PMC6929533; DOI: 10.1093/ije/dyz173;

van den Heuvel ER, Griffith LE, Sohel N, Fortier I, Muniz-Terrera G, Raina P. Latent variable models for harmonization of test scores: A case study on memory. Biom J. 2020 01; 62(1):34-52. PMID: 31583767

van Buel EM, Meddens MJM, Arnoldussen EA, van den Heuvel ER, Bohlmeijer WC, den Boer JA, Muller Kobold A, Boonman-de Winter LJM, van Rumpt D, Timmers LFJ, Veerman MFA, Kamphuis JS, Gladkevich AV, Schoevers RA, Luiten PGM, Eisel ULM, Bosker FJ, Klein HC. Major depressive disorder is associated with changes in a cluster of serum and urine biomarkers. J Psychosom Res. 2019 10; 125:109796. PMID: 31470255; DOI: 10.1016/j.jpsychores.2019.109796;

Tannenbaum C, Fritel X, Halme A, van den Heuvel E, Jutai J, Wagg A. Long-term effect of community-based continence promotion on urinary symptoms, falls and healthy active life expectancy among older women: cluster randomised trial. Age Ageing. 2019 07 01; 48(4):526-532. PMID: 31220200; PMCID: PMC6593322; DOI: 10.1093/ageing/afz038;

Obeid R, Heil SG, Verhoeven MMA, van den Heuvel EGHM, de Groot LCPGM, Eussen SJPM. Vitamin B12 Intake From Animal Foods, Biomarkers, and Health Aspects. Front Nutr. 2019; 6:93. PMID: 31316992; PMCID: PMC6611390; DOI: 10.3389/fnut.2019.00093;

Märtson AG, Veringa A, van den Heuvel ER, Bakker M, Touw DJ, van der Werf TS, Span LFR, Alffenaar JC. Posaconazole therapeutic drug monitoring in clinical practice and longitudinal analysis of the effect of routine laboratory measurements on posaconazole concentrations. Mycoses. 2019 Aug; 62(8):698-705. PMID: 31145490; PMCID: PMC6852019; DOI: 10.1111/myc.12948;

Vroom AJ, Timmermans A, Bongers MY, van den Heuvel ER, Geomini PMAJ, van Hanegem N. Diagnostic accuracy of saline contrast sonohysterography in detecting endometrial polyps in women with postmenopausal bleeding: systematic review and meta-analysis. Ultrasound Obstet Gynecol. 2019 Jul; 54(1):28-34. PMID: 30693579; DOI: 10.1002/uog.20229;

Griffith LE, Gilsing A, Mangin D, Patterson C, van den Heuvel E, Sohel N, St John P, van den Akker M, Raina P. Multimorbidity Frameworks Impact Prevalence and Relationships with Patient-Important Outcomes. J Am Geriatr Soc. 2019 08; 67(8):1632-1640. PMID: 30957230; DOI: 10.1111/jgs.15921;

Sponholtz TR, van den Heuvel ER, Xanthakis V, Vasan RS. Association of Variability in Body Mass Index and Metabolic Health With Cardiometabolic Disease Risk. J Am Heart Assoc. 2019 04 02; 8(7):e010793.View Related Profiles.

Van Den Heuvel, Edwin
Sponholtz, Todd
Xanthakis, Vanessa

PMID: 31025893; PMCID: PMC6509716; DOI: 10.1161/JAHA.118.010793;

Cernak V, Oude Lansink-Hartgring A, van den Heuvel ER, Verschuuren EAM, van der Bij W, Scheeren TWL, Engels GE, de Geus AF, Erasmus ME, de Vries AJ. Incidence of Massive Transfusion and Overall Transfusion Requirements During Lung Transplantation Over a 25-Year Period. J Cardiothorac Vasc Anesth. 2019 Sep; 33(9):2478-2486. PMID: 31147209; DOI: 10.1053/j.jvca.2019.03.060;

Raina P, Gilsing A, Freisling H, van den Heuvel E, Sohel N, Jenab M, Ferrari P, Tjønneland A, Benetou V, Picavet S, Eriksson S, Schöttker B, Brenner H, Saum KU, Perna L, Wilsgaard T, Trichopoulou A, Boffetta P, Griffith LE. The Combined Effect of Cancer and Cardiometabolic Conditions on the Mortality Burden in Older Adults. J Gerontol A Biol Sci Med Sci. 2019 02 15; 74(3):366-372. PMID: 29562321; DOI: 10.1093/gerona/gly053;

Demetrashvili N, Smidt N, Snieder H, van den Heuvel ER, Wit EC. Variance Components Models for Analysis of Big Family Data of Health Outcomes in the Lifelines Cohort Study. Twin Res Hum Genet. 2019 02; 22(1):4-13. PMID: 30944055; DOI: 10.1017/thg.2019.1;

Märtson AG, Veringa A, Bakker M, van den Heuvel ER, Touw DJ, van der Werf TS, Span LFR, C Alffenaar JW. Posaconazole trough concentrations are not influenced by inflammation: A prospective study. Int J Antimicrob Agents. 2019 Mar; 53(3):325-329. PMID: 30639628; DOI: 10.1016/j.ijantimicag.2019.01.006;

de Vries AJ, Vermeijden WJ, van Pelt LJ, van den Heuvel ER, van Oeveren W. Additional filtering of blood from a cell salvage device is not likely to show important additional benefits in outcome in cardiac surgery. Transfusion. 2019 03; 59(3):989-994. PMID: 30610759; DOI: 10.1111/trf.15130;

Briët JM, Mourits MJ, van Leeuwen BL, van den Heuvel ER, Kenkhuis MJ, Arts HJ, de Bock GH. Age should not be a limiting factor in laparoscopic surgery: a prospective multicenter cohort study on quality of life after laparoscopic hysterectomy. Clin Interv Aging. 2018; 13:2517-2526. PMID: 30587944; PMCID: PMC6296188; DOI: 10.2147/CIA.S172965;

van Nieuwenhuijzen EJ, Sailer MF, van den Heuvel ER, Rensink S, Adan OCG, Samson RA. Vegetable oils as carbon and energy source for Aureobasidium melanogenum in batch cultivation. Microbiologyopen. 2019 06; 8(6):e00764. PMID: 30515994; PMCID: PMC6562153; DOI: 10.1002/mbo3.764;

Bullens LM, Hulsenboom ADJ, Moors S, Joshi R, van Runnard Heimel PJ, van der Hout-van der Jagt MB, van den Heuvel ER, Guid Oei S. Correction to: Intrauterine resuscitation during the second stage of term labour by maternal hyperoxygenation versus conventional care: study protocol for a randomised controlled trial (INTEREST O2). Trials. 2018 10 23; 19(1):580. PMID: 30352596; PMCID: PMC6198427; DOI: 10.1186/s13063-018-2963-2;

Stiekema APM, Islam MA, Liemburg EJ, Castelein S, van den Heuvel ER, van Weeghel J, Aleman A, Bruggeman R, van der Meer L, Alizadeh BZ, Bartels-Velthuis AA, van Beveren NJ, Bruggeman R, Cahn W, de Haan L, Delespaul P, Meijer CJ, Myin-Germeys I, Kahn RS, Schirmbeck F, Simons CJP, van Haren NEM, van Os J, van Winkel R. Corrigendum to "Long-term course of negative symptom subdomains and relationship with outcome in patients with a psychotic disorder" [Schizophr. Res. 193 (2018) 173-181]. Schizophr Res. 2019 Feb; 204:462-463. PMID: 30314649; DOI: 10.1016/j.schres.2018.10.003;

Islam MA, Habtewold TD, van Es FD, Quee PJ, van den Heuvel ER, Alizadeh BZ, Bruggeman R. Long-term cognitive trajectories and heterogeneity in patients with schizophrenia and their unaffected siblings. Acta Psychiatr Scand. 2018 12; 138(6):591-604. PMID: 30242827; PMCID: PMC6220939; DOI: 10.1111/acps.12961;

Zhan Z, de Bock GH, van den Heuvel ER. Optimal unidirectional switch designs. Stat Med. 2018 11 10; 37(25):3573-3588. PMID: 30003557; DOI: 10.1002/sim.7853;

van den Heuvel ER, Vasan RS. Statistics in cardiovascular medicine: there is still gold in the old. Heart. 2018 07; 104(14):1227. PMID: 29945950; DOI: 10.1136/heartjnl-2018-313303;

Groothuis-Oudshoorn CGM, van den Heuvel ER, Krabbe PFM. A preference-based item response theory model to measure health: concept and mathematics of the multi-attribute preference response model. BMC Med Res Methodol. 2018 06 22; 18(1):62. PMID: 29929469; PMCID: PMC6013962; DOI: 10.1186/s12874-018-0516-8;

van Loon SL, Wilbik AM, Kaymak U, van den Heuvel ER, Scharnhorst V, Boer AK. Improved testing for vitamin B12 deficiency: correcting MMA for eGFR reduces the number of patients classified as vitamin B12 deficient. Ann Clin Biochem. 2018 Nov; 55(6):685-692. PMID: 29874929; DOI: 10.1177/0004563218778300;

Van Dijk LJ, Lie MA, Van den Heuvel ER, Van der Weijden GA. Adult periodontitis treated with a new device for subgingival lavage-a randomized controlled clinical trial using a split-mouth design. Int J Dent Hyg. 2018 Nov; 16(4):559-568. PMID: 29708654; DOI: 10.1111/idh.12344;

Heineman KR, Schendelaar P, Van den Heuvel ER, Hadders-Algra M. Motor development in infancy is related to cognitive function at 4 years of age. Dev Med Child Neurol. 2018 11; 60(11):1149-1155. PMID: 29633244; DOI: 10.1111/dmcn.13761;

Bullens LM, Hulsenboom ADJ, Moors S, Joshi R, van Runnard Heimel PJ, van der Hout-van der Jagt MB, van den Heuvel ER, Guid Oei S. Intrauterine resuscitation during the second stage of term labour by maternal hyperoxygenation versus conventional care: study protocol for a randomised controlled trial (INTEREST O2). Trials. 2018 Mar 23; 19(1):195. PMID: 29566729; PMCID: PMC5865381; DOI: 10.1186/s13063-018-2567-x;

Manju MA, Van Den Heuvel ER, IJzerman-Boon PC. A comparison of spiking experiments to estimate the detection proportion of qualitative microbiological methods. J Biopharm Stat. 2019; 29(1):30-55. PMID: 29553884; DOI: 10.1080/10543406.2018.1452027;

Broekstra DC, Groen H, Molenkamp S, Werker PMN, van den Heuvel ER. A Systematic Review and Meta-Analysis on the Strength and Consistency of the Associations between Dupuytren Disease and Diabetes Mellitus, Liver Disease, and Epilepsy. Plast Reconstr Surg. 2018 03; 141(3):367e-379e. PMID: 29481401; PMCID: PMC5841852; DOI: 10.1097/PRS.0000000000004120;

Zandstra ARE, Ormel J, Dietrich A, van den Heuvel ER, Hoekstra PJ, Hartman CA. Sensitivity to psychosocial chronic stressors and adolescents' externalizing problems: Combined moderator effects of resting heart rate and parental psychiatric history. Biol Psychol. 2018 04; 134:20-29. PMID: 29471016; DOI: 10.1016/j.biopsycho.2018.02.009;

Broekstra DC, van den Heuvel ER, Lanting R, Werker PMN. Measurement properties of the Dutch Unité Rhumatologique des Affections de la Main and its ability to measure change due to Dupuytren's disease progression compared with the Michigan Hand outcomes Questionnaire. J Hand Surg Eur Vol. 2018 Oct; 43(8):855-863. PMID: 29439589; PMCID: PMC6139982; DOI: 10.1177/1753193417752891;

Hamedpour V, Postma GJ, van den Heuvel E, Jansen JJ, Suzuki K, Citterio D. Chemometrics-assisted microfluidic paper-based analytical device for the determination of uric acid by silver nanoparticle plasmon resonance. Anal Bioanal Chem. 2018 Mar; 410(9):2305-2313. PMID: 29435632; DOI: 10.1007/s00216-018-0879-z;

Schneeberger C, Erwich JJHM, van den Heuvel ER, Mol BWJ, Ott A, Geerlings SE. Asymptomatic bacteriuria and urinary tract infection in pregnant women with and without diabetes: Cohort study. Eur J Obstet Gynecol Reprod Biol. 2018 Mar; 222:176-181. PMID: 29338897; DOI: 10.1016/j.ejogrb.2017.12.013;

Baljé-Volkers C, Mzolo T, Talens E, IJzerman-Boon P, Van den Heuvel E. Equivalence testing for similarity in bioassays using bioequivalence criteria on the relative bioactivity. Pharm Stat. 2018 02; 17(1):12-24. PMID: 29110389; DOI: 10.1002/pst.1832;

Phi XA, Houssami N, Hooning MJ, Riedl CC, Leach MO, Sardanelli F, Warner E, Trop I, Saadatmand S, Tilanus-Linthorst MMA, Helbich TH, van den Heuvel ER, de Koning HJ, Obdeijn IM, de Bock GH. Accuracy of screening women at familial risk of breast cancer without a known gene mutation: Individual patient data meta-analysis. Eur J Cancer. 2017 11; 85:31-38. PMID: 28886475; DOI: 10.1016/j.ejca.2017.07.055;

Goelema MS, Regis M, Haakma R, van den Heuvel ER, Markopoulos P, Overeem S. Determinants of perceived sleep quality in normal sleepers. Behav Sleep Med. 2019 Jul-Aug; 17(4):388-397. PMID: 28929803; DOI: 10.1080/15402002.2017.1376205;

Zhan Z, Verberne CJ, van den Heuvel ER, Grossmann I, Ranchor AV, Wiggers T, de Bock GH. Psychological effects of the intensified follow-up of the CEAwatch trial after treatment for colorectal cancer. PLoS One. 2017; 12(9):e0184740. PMID: 28922422; PMCID: PMC5603155; DOI: 10.1371/journal.pone.0184740;

Bruins J, Jörg F, van den Heuvel ER, Bartels-Velthuis AA, Corpeleijn E, Muskiet FAJ, Pijnenborg GHM, Bruggeman R. The relation of vitamin D, metabolic risk and negative symptom severity in people with psychotic disorders. Schizophr Res. 2018 05; 195:513-518. PMID: 28927862; DOI: 10.1016/j.schres.2017.08.059;

Bruins J, Pijnenborg GHM, van den Heuvel ER, Visser E, Corpeleijn E, Bartels-Velthuis AA, Bruggeman R, Jörg F. Persistent Low Rates of Treatment of Metabolic Risk Factors in People With Psychotic Disorders: A PHAMOUS Study. J Clin Psychiatry. 2017 Sep/Oct; 78(8):1117-1125. PMID: 28406264; DOI: 10.4088/JCP.16m10831;

Stiekema APM, Islam MA, Liemburg EJ, Castelein S, van den Heuvel ER, van Weeghel J, Aleman A, Bruggeman R, van der Meer L. Long-term course of negative symptom subdomains and relationship with outcome in patients with a psychotic disorder. Schizophr Res. 2018 03; 193:173-181. PMID: 28648915; DOI: 10.1016/j.schres.2017.06.024;

Islam MA, Khan MFH, Quee PJ, Snieder H, van den Heuvel ER, Bruggeman R, Alizadeh BZ. Familial liability to psychosis is a risk factor for multimorbidity in people with psychotic disorders and their unaffected siblings. Eur Psychiatry. 2017 09; 45:81-89. PMID: 28750277; DOI: 10.1016/j.eurpsy.2017.05.001;

Annema C, Roodbol PF, Van den Heuvel ER, Metselaar HJ, Van Hoek B, Porte RJ, Ranchor AV. Trajectories of anxiety and depression in liver transplant candidates during the waiting-list period. Br J Health Psychol. 2017 09; 22(3):481-501. PMID: 28474774; DOI: 10.1111/bjhp.12241;

Verberne CJ, Zhan Z, van den Heuvel ER, Oppers F, de Jong AM, Grossmann I, Klaase JM, de Bock GH, Wiggers T. Survival analysis of the CEAwatch multicentre clustered randomized trial. Br J Surg. 2017 Jul; 104(8):1069-1077. PMID: 28376235; DOI: 10.1002/bjs.10535;

De Vries AJ, Lansink-Hartgring AO, Fernhout FJ, Huet RCG, van den Heuvel ER. The activated clotting time in cardiac surgery: should Celite or kaolin be used? Interact Cardiovasc Thorac Surg. 2017 04 01; 24(4):549-554. PMID: 28108578; DOI: 10.1093/icvts/ivw435;

Li G, Taljaard M, Van den Heuvel ER, Levine MA, Cook DJ, Wells GA, Devereaux PJ, Thabane L. An introduction to multiplicity issues in clinical trials: the what, why, when and how. Int J Epidemiol. 2017 04 01; 46(2):746-755. PMID: 28025257; DOI: 10.1093/ije/dyw320;

Darvishian M, van den Heuvel ER, Bissielo A, Castilla J, Cohen C, Englund H, Gefenaite G, Huang WT, la Bastide-van Gemert S, Martinez-Baz I, McAnerney JM, Ntshoe GM, Suzuki M, Turner N, Hak E. Effectiveness of seasonal influenza vaccination in community-dwelling elderly people: an individual participant data meta-analysis of test-negative design case-control studies. Lancet Respir Med. 2017 03; 5(3):200-211. PMID: 28189522; DOI: 10.1016/S2213-2600(17)30043-7;

Fortier I, Raina P, Van den Heuvel ER, Griffith LE, Craig C, Saliba M, Doiron D, Stolk RP, Knoppers BM, Ferretti V, Granda P, Burton P. Maelstrom Research guidelines for rigorous retrospective data harmonization. Int J Epidemiol. 2017 02 01; 46(1):103-105. PMID: 27272186; PMCID: PMC5407152; DOI: 10.1093/ije/dyw075;

Zhan Z, de Bock GH, van den Heuvel ER. Statistical methods for unidirectional switch designs: Past, present, and future. Stat Methods Med Res. 2018 09; 27(9):2872-2882. PMID: 28125927; DOI: 10.1177/0962280216689280;

Griffith LE, van den Heuvel E, Raina P, Fortier I, Sohel N, Hofer SM, Payette H, Wolfson C, Belleville S, Kenny M, Doiron D. Comparison of Standardization Methods for the Harmonization of Phenotype Data: An Application to Cognitive Measures. Am J Epidemiol. 2016 11 15; 184(10):770-778. PMID: 27769990; PMCID: PMC5141949; DOI: 10.1093/aje/kww098;

Ter Avest M, Veringa A, van den Heuvel ER, Kosterink JG, Schölvinck EH, Tissing WJ, Alffenaar JC. The effect of inflammation on voriconazole trough concentrations in children. Br J Clin Pharmacol. 2017 03; 83(3):678-680. PMID: 27862167; PMCID: PMC5306482; DOI: 10.1111/bcp.13151;

Griffith LE, Raina P, Levasseur M, Sohel N, Payette H, Tuokko H, van den Heuvel E, Wister A, Gilsing A, Patterson C. Functional disability and social participation restriction associated with chronic conditions in middle-aged and older adults. J Epidemiol Community Health. 2017 04; 71(4):381-389. PMID: 27754857; DOI: 10.1136/jech-2016-207982;

Broekstra DC, van den Heuvel ER, Lanting R, Harder T, Smits I, Werker PMN. Dupuytren disease is highly prevalent in male field hockey players aged over 60 years. Br J Sports Med. 2018 Oct; 52(20):1327-1331. PMID: 27660370; DOI: 10.1136/bjsports-2016-096236;

Schendelaar P, La Bastide-Van Gemert S, Heineman MJ, Middelburg KJ, Seggers J, Van den Heuvel ER, Hadders-Algra M. Subfertility factors rather than assisted conception factors affect cognitive and behavioural development of 4-year-old singletons. Reprod Biomed Online. 2016 Dec; 33(6):752-762. PMID: 27665057; DOI: 10.1016/j.rbmo.2016.08.021;

Veringa A, Ter Avest M, Span LF, van den Heuvel ER, Touw DJ, Zijlstra JG, Kosterink JG, van der Werf TS, Alffenaar JC. Voriconazole metabolism is influenced by severe inflammation: a prospective study. J Antimicrob Chemother. 2017 01; 72(1):261-267. PMID: 27601292; DOI: 10.1093/jac/dkw349;

Zwanenburg RJ, Bocca G, Ruiter SA, Dillingh JH, Flapper BC, van den Heuvel ER, van Ravenswaaij-Arts CM. Is there an effect of intranasal insulin on development and behaviour in Phelan-McDermid syndrome? A randomized, double-blind, placebo-controlled trial. Eur J Hum Genet. 2016 12; 24(12):1696-1701. PMID: 27577546; PMCID: PMC5117914; DOI: 10.1038/ejhg.2016.109;

Gerretzen J, Szymanska E, Bart J, Davies AN, van Manen HJ, van den Heuvel ER, Jansen JJ, Buydens LM. Boosting model performance and interpretation by entangling preprocessing selection and variable selection. Anal Chim Acta. 2016 Sep 28; 938:44-52. PMID: 27619085; DOI: 10.1016/j.aca.2016.08.022;

van der Velde AR, Meijers WC, van den Heuvel ER, Bakker SJ, van Gilst WH, van der Harst P, Hillege H, de Boer RA. Determinants of temporal changes in galectin-3 level in the general population: Data of PREVEND. Int J Cardiol. 2016 Nov 01; 222:385-390. PMID: 27505321; DOI: 10.1016/j.ijcard.2016.07.241;

Zhan Z, de Bock GH, Wiggers T, van den Heuvel E. The analysis of terminal endpoint events in stepped wedge designs. Stat Med. 2016 10 30; 35(24):4413-4426. PMID: 27311403; DOI: 10.1002/sim.7004;

Tjon Pian Gi RE, San Giorgi MR, Pawlita M, Michel A, van Hemel BM, Schuuring EM, van den Heuvel ER, van der Laan BF, Dikkers FG. Immunological response to quadrivalent HPV vaccine in treatment of recurrent respiratory papillomatosis. Eur Arch Otorhinolaryngol. 2016 Oct; 273(10):3231-6. PMID: 27188508; PMCID: PMC5014878; DOI: 10.1007/s00405-016-4085-3;

Sobhani S, van den Heuvel ER, Dekker R, Postema K, Kluitenberg B, Bredeweg SW, Hijmans JM. Biomechanics of running with rocker shoes. J Sci Med Sport. 2017 Jan; 20(1):38-44. PMID: 27167559; DOI: 10.1016/j.jsams.2016.04.008;

Zwanenburg RJ, Ruiter SA, van den Heuvel ER, Flapper BC, Van Ravenswaaij-Arts CM. Developmental phenotype in Phelan-McDermid (22q13.3 deletion) syndrome: a systematic and prospective study in 34 children. J Neurodev Disord. 2016; 8:16. PMID: 27118998; PMCID: PMC4845478; DOI: 10.1186/s11689-016-9150-0;

Encalada Ventura MA, van Wanrooy MJ, Span LF, Rodgers MG, van den Heuvel ER, Uges DR, van der Werf TS, Kosterink JG, Alffenaar JW. Longitudinal Analysis of the Effect of Inflammation on Voriconazole Trough Concentrations. Antimicrob Agents Chemother. 2016 05; 60(5):2727-31. PMID: 26883707; PMCID: PMC4862487; DOI: 10.1128/AAC.02830-15;

de Vries YA, de Jonge P, van den Heuvel E, Turner EH, Roest AM. Influence of baseline severity on antidepressant efficacy for anxiety disorders: meta-analysis and meta-regression. Br J Psychiatry. 2016 06; 208(6):515-21. PMID: 26989093; DOI: 10.1192/bjp.bp.115.173450;

Janse IC, Hellinga J, Blok JL, van den Heuvel ER, Spoo JR, Jonkman MF, Terra JB, Horváth B. Skin-Tissue-sparing Excision with Electrosurgical Peeling: A Case Series in Hidradenitis Suppurativa. Acta Derm Venereol. 2016 Mar; 96(3):390-1. PMID: 26463363; DOI: 10.2340/00015555-2258;

Phi XA, Saadatmand S, De Bock GH, Warner E, Sardanelli F, Leach MO, Riedl CC, Trop I, Hooning MJ, Mandel R, Santoro F, Kwan-Lim G, Helbich TH, Tilanus-Linthorst MM, van den Heuvel ER, Houssami N. Contribution of mammography to MRI screening in BRCA mutation carriers by BRCA status and age: individual patient data meta-analysis. Br J Cancer. 2016 Mar 15; 114(6):631-7. PMID: 26908327; PMCID: PMC4800299; DOI: 10.1038/bjc.2016.32;

Scholte-Stalenhoef AN, la Bastide-van Gemert S, van de Willige G, Dost-Otter R, Visser E, Liemburg EJ, Knegtering H, van den Heuvel ER, Schoevers RA, Pijnenborg GHM, Bruggeman R. Personality and coping in first episode psychosis linked to mental health care use. Psychiatry Res. 2016 Apr 30; 238:218-224. PMID: 27086236; DOI: 10.1016/j.psychres.2016.02.035;

Bruins J, Pijnenborg MG, Bartels-Velthuis AA, Visser E, van den Heuvel ER, Bruggeman R, Jörg F. Cannabis use in people with severe mental illness: The association with physical and mental health--a cohort study. A Pharmacotherapy Monitoring and Outcome Survey study. J Psychopharmacol. 2016 Apr; 30(4):354-62. PMID: 26883305; DOI: 10.1177/0269881116631652;

San Giorgi MR, van den Heuvel ER, Tjon Pian Gi RE, Brunings JW, Chirila M, Friedrich G, Golusinski W, Graupp M, Horcasitas Pous RA, Ilmarinen T, Jackowska J, Koelmel JC, Ferran Vilà F, Weichbold V, Wierzbicka M, Dikkers FG. Age of onset of recurrent respiratory papillomatosis: a distribution analysis. Clin Otolaryngol. 2016 Oct; 41(5):448-53. PMID: 26460806; DOI: 10.1111/coa.12565;

Vaez A, van der Most PJ, Prins BP, Snieder H, van den Heuvel E, Alizadeh BZ, Nolte IM. lodGWAS: a software package for genome-wide association analysis of biomarkers with a limit of detection. Bioinformatics. 2016 05 15; 32(10):1552-4. PMID: 26803157; DOI: 10.1093/bioinformatics/btw021;

Lanting R, van den Heuvel ER, Werker PM. Clusters in Short-term Disease Course in Participants With Primary Dupuytren Disease. J Hand Surg Am. 2016 Mar; 41(3):354-61; quiz 361. PMID: 26787409; DOI: 10.1016/j.jhsa.2015.10.027;

Lako IM, Taxis K, van den Heuvel ER, Leenaars CHC, Burger H, Wiersma D, Slooff CJ, Knegtering H, Bruggeman R. Altered emotional experiences attributed to antipsychotic medications - A potential link with estimated dopamine D2 receptor occupancy. Psychiatry Res. 2016 Feb 28; 236:9-14. PMID: 26791397; DOI: 10.1016/j.psychres.2016.01.009;

Gerretzen J, Szymanska E, Jansen JJ, Bart J, van Manen HJ, van den Heuvel ER, Buydens LM. Simple and Effective Way for Data Preprocessing Selection Based on Design of Experiments. Anal Chem. 2015 Dec 15; 87(24):12096-103. PMID: 26632985; DOI: 10.1021/acs.analchem.5b02832;

van der Elst KC, Brouwers CH, van den Heuvel ER, van Wanrooy MJ, Uges DR, van der Werf TS, Kosterink JG, Span LF, Alffenaar JW. Subtherapeutic Posaconazole Exposure and Treatment Outcome in Patients With Invasive Fungal Disease. Ther Drug Monit. 2015 Dec; 37(6):766-71. PMID: 26565789; DOI: 10.1097/FTD.0000000000000235;

Nooraee N, Abegaz F, Ormel J, Wit E, van den Heuvel ER. An approximate marginal logistic distribution for the analysis of longitudinal ordinal data. Biometrics. 2016 Mar; 72(1):253-61. PMID: 26458164; DOI: 10.1111/biom.12414;

Nguyen HT, Nguyen TD, van den Heuvel ER, Haaijer-Ruskamp FM, Taxis K. Medication Errors in Vietnamese Hospitals: Prevalence, Potential Outcome and Associated Factors. PLoS One. 2015; 10(9):e0138284. PMID: 26383873; PMCID: PMC4575184; DOI: 10.1371/journal.pone.0138284;

Zandstra AR, Hartman CA, Nederhof E, van den Heuvel ER, Dietrich A, Hoekstra PJ, Ormel J. Chronic Stress and Adolescents' Mental Health: Modifying Effects of Basal Cortisol and Parental Psychiatric History. The TRAILS Study. J Abnorm Child Psychol. 2015 Aug; 43(6):1119-30. PMID: 25617009; PMCID: PMC4494132; DOI: 10.1007/s10802-014-9970-x;

Verberne CJ, Zhan Z, van den Heuvel E, Grossmann I, Doornbos PM, Havenga K, Manusama E, Klaase J, van der Mijle HC, Lamme B, Bosscha K, Baas P, van Ooijen B, Nieuwenhuijzen G, Marinelli A, van der Zaag E, Wasowicz D, de Bock GH, Wiggers T. Intensified follow-up in colorectal cancer patients using frequent Carcino-Embryonic Antigen (CEA) measurements and CEA-triggered imaging: Results of the randomized "CEAwatch" trial. Eur J Surg Oncol. 2015 Sep; 41(9):1188-96. PMID: 26184850

Papageorgiou K, Vermeulen KM, Schroevers MJ, Stiggelbout AM, Buskens E, Krabbe PF, van den Heuvel E, Ranchor AV. Do individuals with and without depression value depression differently? And if so, why? Qual Life Res. 2015 Nov; 24(11):2565-75. PMID: 26038219; PMCID: PMC4592699; DOI: 10.1007/s11136-015-1018-3;

Kuiper J, van den Heuvel ER, Swertz MA. The hybrid synthetic microdata platform: a method for statistical disclosure control. Biopreserv Biobank. 2015 Jun; 13(3):178-82. PMID: 26035007; PMCID: PMC4559158; DOI: 10.1089/bio.2014.0069;

Kuiper JS, Zuidersma M, Oude Voshaar RC, Zuidema SU, van den Heuvel ER, Stolk RP, Smidt N. Social relationships and risk of dementia: A systematic review and meta-analysis of longitudinal cohort studies. Ageing Res Rev. 2015 Jul; 22:39-57. PMID: 25956016; DOI: 10.1016/j.arr.2015.04.006;

Encalada Ventura MA, Span LF, van den Heuvel ER, Groothuis GM, Alffenaar JW. Influence of inflammation on voriconazole metabolism. Antimicrob Agents Chemother. 2015 May; 59(5):2942-3. PMID: 25733507; PMCID: PMC4394835; DOI: 10.1128/AAC.04789-14;

Demetrashvili N, Van den Heuvel ER. Confidence intervals for intraclass correlation coefficients in a nonlinear dose-response meta-analysis. Biometrics. 2015 Jun; 71(2):548-55. PMID: 25703393; DOI: 10.1111/biom.12275;

Stiekema AP, Quee PJ, Dethmers M, van den Heuvel ER, Redmeijer JE, Rietberg K, Stant AD, Swart M, van Weeghel J, Aleman A, Velligan DI, Schoevers RA, Bruggeman R, van der Meer L. Effectiveness and cost-effectiveness of cognitive adaptation training as a nursing intervention in long-term residential patients with severe mental illness: study protocol for a randomized controlled trial. Trials. 2015 Feb 12; 16:49. PMID: 25887511; PMCID: PMC4327948; DOI: 10.1186/s13063-015-0566-8;

Broekstra DC, Lanting R, Werker PM, van den Heuvel ER. Intra- and inter-observer agreement on diagnosis of Dupuytren disease, measurements of severity of contracture, and disease extent. Man Ther. 2015 Aug; 20(4):580-6. PMID: 25682557; DOI: 10.1016/j.math.2015.01.010;

Bantema-Joppe EJ, de Bock GH, Woltman-van Iersel M, Busz DM, Ranchor AV, Langendijk JA, Maduro JH, van den Heuvel ER. The impact of age on changes in quality of life among breast cancer survivors treated with breast-conserving surgery and radiotherapy. Br J Cancer. 2015 Feb 17; 112(4):636-43. PMID: 25602967; PMCID: PMC4333491; DOI: 10.1038/bjc.2014.632;

Van Balen LC, Dijkstra LJ, Bos AF, Van Den Heuvel ER, Hadders-Algra M. Development of postural adjustments during reaching in infants at risk for cerebral palsy from 4 to 18 months. Dev Med Child Neurol. 2015 Jul; 57(7):668-676. PMID: 25645150; DOI: 10.1111/dmcn.12699;

Blok JL, Boersma M, Terra JB, Spoo JR, Leeman FW, van den Heuvel ER, Huizinga J, Jonkman MF, Horváth B. Surgery under general anaesthesia in severe hidradenitis suppurativa: a study of 363 primary operations in 113 patients. J Eur Acad Dermatol Venereol. 2015 Aug; 29(8):1590-7. PMID: 25589154; DOI: 10.1111/jdv.12952;

de Vries AG, Huiting HG, van den Heuvel ER, L'Abée C, Corpeleijn E, Stolk RP. An activity stimulation programme during a child's first year reduces some indicators of adiposity at the age of two-and-a-half. Acta Paediatr. 2015 Apr; 104(4):414-21. PMID: 25425024; DOI: 10.1111/apa.12880;

Phi XA, Houssami N, Obdeijn IM, Warner E, Sardanelli F, Leach MO, Riedl CC, Trop I, Tilanus-Linthorst MM, Mandel R, Santoro F, Kwan-Lim G, Helbich TH, de Koning HJ, Van den Heuvel ER, de Bock GH. Magnetic resonance imaging improves breast screening sensitivity in BRCA mutation carriers age = 50 years: evidence from an individual patient data meta-analysis. J Clin Oncol. 2015 Feb 01; 33(4):349-56. PMID: 25534390; DOI: 10.1200/JCO.2014.56.6232;

van Loo HM, van den Heuvel ER, Schoevers RA, Anselmino M, Carney RM, Denollet J, Doyle F, Freedland KE, Grace SL, Hosseini SH, Parakh K, Pilote L, Rafanelli C, Roest AM, Sato H, Steeds RP, Kessler RC, de Jonge P. Sex dependent risk factors for mortality after myocardial infarction: individual patient data meta-analysis. BMC Med. 2014 Dec 17; 12:242. PMID: 25515680; PMCID: PMC4292997; DOI: 10.1186/s12916-014-0242-y;

Griffith LE, van den Heuvel E, Fortier I, Sohel N, Hofer SM, Payette H, Wolfson C, Belleville S, Kenny M, Doiron D, Raina P. Statistical approaches to harmonize data on cognitive measures in systematic reviews are rarely reported. J Clin Epidemiol. 2015 Feb; 68(2):154-62. PMID: 25497980; PMCID: PMC4685455; DOI: 10.1016/j.jclinepi.2014.09.003;

Visser E, de Bock GH, Messelink EJ, Schram AJ, Kollen BJ, la Bastide-van Gemert S, van den Heuvel ER, Berger MY, Dekker JH. Active encouragement of older women with urinary incontinence in primary care to undergo diagnosis and treatment: a matched-pair cluster randomized controlled trial. Maturitas. 2015 Feb; 80(2):212-9. PMID: 25534171; DOI: 10.1016/j.maturitas.2014.11.015;

IJzerman-Boon PC, van den Heuvel ER. Validation of qualitative microbiological test methods. Pharm Stat. 2015 Mar-Apr; 14(2):120-8. PMID: 25412584; DOI: 10.1002/pst.1663;

Van den Heuvel ER, Zwanenburg RJ, Van Ravenswaaij-Arts CM. A stepped wedge design for testing an effect of intranasal insulin on cognitive development of children with Phelan-McDermid syndrome: A comparison of different designs. Stat Methods Med Res. 2017 04; 26(2):766-775. PMID: 25411323; DOI: 10.1177/0962280214558864;

Vermeijden WJ, van Klarenbosch J, Gu YJ, Mariani MA, Buhre WF, Scheeren TW, Hagenaars JA, Tan ME, Haenen JS, Bras L, van Oeveren W, van den Heuvel ER, de Vries AJ. Effects of cell-saving devices and filters on transfusion in cardiac surgery: a multicenter randomized study. Ann Thorac Surg. 2015 Jan; 99(1):26-32. PMID: 25440265; DOI: 10.1016/j.athoracsur.2014.08.027;

Demissei BG, Postmus D, Valente MA, van der Harst P, van Gilst WH, Van den Heuvel ER, Hillege HL. Should non-cardiovascular mortality be considered in the SCORE model? Findings from the Prevention of Renal and Vascular End-stage Disease (PREVEND) cohort. Eur J Epidemiol. 2015 Jan; 30(1):47-56. PMID: 25377534; DOI: 10.1007/s10654-014-9967-3;

Darvishian M, Bijlsma MJ, Hak E, van den Heuvel ER. Effectiveness of seasonal influenza vaccine in community-dwelling elderly people: a meta-analysis of test-negative design case-control studies. Lancet Infect Dis. 2014 Dec; 14(12):1228-39. PMID: 25455990; DOI: 10.1016/S1473-3099(14)70960-0;

Dlabac-de Lange JJ, Bais L, van Es FD, Visser BG, Reinink E, Bakker B, van den Heuvel ER, Aleman A, Knegtering H. Efficacy of bilateral repetitive transcranial magnetic stimulation for negative symptoms of schizophrenia: results of a multicenter double-blind randomized controlled trial. Psychol Med. 2015 Apr; 45(6):1263-75. PMID: 25354751; DOI: 10.1017/S0033291714002360;

den Dekker MAM, Pelgrim GJ, Pundziute G, van den Heuvel ER, Oudkerk M, Vliegenthart R. Hemodynamic significance of coronary stenosis by vessel attenuation measurement on CT compared with adenosine perfusion MRI. Eur J Radiol. 2015 Jan; 84(1):92-99. PMID: 25467226; DOI: 10.1016/j.ejrad.2014.10.012;

Schendelaar P, Van den Heuvel ER, Heineman MJ, La Bastide-Van Gemert S, Middelburg KJ, Seggers J, Hadders-Algra M. Increased time to pregnancy is associated with less optimal neurological condition in 4-year-old singletons, in vitro fertilization itself is not. Hum Reprod. 2014 Dec; 29(12):2773-86. PMID: 25316454; DOI: 10.1093/humrep/deu252;

Gaye A, Marcon Y, Isaeva J, LaFlamme P, Turner A, Jones EM, Minion J, Boyd AW, Newby CJ, Nuotio ML, Wilson R, Butters O, Murtagh B, Demir I, Doiron D, Giepmans L, Wallace SE, Budin-Ljøsne I, Oliver Schmidt C, Boffetta P, Boniol M, Bota M, Carter KW, deKlerk N, Dibben C, Francis RW, Hiekkalinna T, Hveem K, Kvaløy K, Millar S, Perry IJ, Peters A, Phillips CM, Popham F, Raab G, Reischl E, Sheehan N, Waldenberger M, Perola M, van den Heuvel E, Macleod J, Knoppers BM, Stolk RP, Fortier I, Harris JR, Woffenbuttel BH, Murtagh MJ, Ferretti V, Burton PR. DataSHIELD: taking the analysis to the data, not the data to the analysis. Int J Epidemiol. 2014 Dec; 43(6):1929-44. PMID: 25261970; PMCID: PMC4276062; DOI: 10.1093/ije/dyu188;

van Wanrooy MJ, Span LF, Rodgers MG, van den Heuvel ER, Uges DR, van der Werf TS, Kosterink JG, Alffenaar JW. Inflammation is associated with voriconazole trough concentrations. Antimicrob Agents Chemother. 2014 Dec; 58(12):7098-101. PMID: 25223994; PMCID: PMC4249508; DOI: 10.1128/AAC.03820-14;

Tjon Pian Gi RE, San Giorgi MR, Slagter-Menkema L, van Hemel BM, van der Laan BF, van den Heuvel ER, Dikkers FG, Schuuring EM. Clinical course of recurrent respiratory papillomatosis: comparison between aggressiveness of human papillomavirus-6 and human papillomavirus-11. Head Neck. 2015 Nov; 37(11):1625-32. PMID: 24955561; DOI: 10.1002/hed.23808;

Lanting R, Nooraee N, Werker PM, van den Heuvel ER. Patterns of Dupuytren disease in fingers: studying correlations with a multivariate ordinal logit model. Plast Reconstr Surg. 2014 Sep; 134(3):483-90. PMID: 24804640; DOI: 10.1097/PRS.0000000000000429;

van der Elst KC, Pereboom M, van den Heuvel ER, Kosterink JG, Schölvinck EH, Alffenaar JW. Insufficient fluconazole exposure in pediatric cancer patients and the need for therapeutic drug monitoring in critically ill children. Clin Infect Dis. 2014 Dec 01; 59(11):1527-33. PMID: 25148892; DOI: 10.1093/cid/ciu657;

Lako IM, Liemburg EJ, Van den Heuvel ER, Knegtering H, Bruggeman R, Taxis K. Estimating dopamine D(2) receptor occupancy for doses of 8 antipsychotics: a meta-analysis: a reply. J Clin Psychopharmacol. 2014 Aug; 34(4):532-3. PMID: 24949704; DOI: 10.1097/JCP.0000000000000172;

Apeldoorn SY, Sterk B, van den Heuvel ER, Schoevers RA, Islam MA, Bruggeman R, Cahn W, deHaan L, Kahn RS, Meijer CJ, Myin-Germeys I, van Os J, Wiersma D. Factors contributing to the duration of untreated psychosis. Schizophr Res. 2014 Sep; 158(1-3):76-81. PMID: 25043913; DOI: 10.1016/j.schres.2014.07.002;

Seggers J, Haadsma ML, Bos AF, Heineman MJ, Middelburg KJ, van den Heuvel ER, Hadders-Algra M. Dysmorphic features and developmental outcome of 2-year-old children. Dev Med Child Neurol. 2014 Nov; 56(11):1078-84. PMID: 25040419; DOI: 10.1111/dmcn.12546;

Quee PJ, Meijer JH, Islam MA, Aleman A, Alizadeh BZ, Meijer CJ, van den Heuvel ER. Premorbid adjustment profiles in psychosis and the role of familial factors. J Abnorm Psychol. 2014 Aug; 123(3):578-587. PMID: 25000154; DOI: 10.1037/a0037189;

Quee PJ, Stiekema AP, Wigman JT, Schneider H, van der Meer L, Maples NJ, van den Heuvel ER, Velligan DI, Bruggeman R. Improving functional outcomes for schizophrenia patients in the Netherlands using Cognitive Adaptation Training as a nursing intervention - A pilot study. Schizophr Res. 2014 Sep; 158(1-3):120-5. PMID: 25000912; DOI: 10.1016/j.schres.2014.06.020;

Yuen WY, Frew JW, Veerman K, van den Heuvel ER, Murrell DF, Jonkman MF. Health-related quality of life in epidermolysis bullosa: Validation of the Dutch QOLEB questionnaire and assessment in the Dutch population. Acta Derm Venereol. 2014 Jul; 94(4):442-7. PMID: 24337132; DOI: 10.2340/00015555-1758;

Bergstra SA, Kluitenberg B, Dekker R, Bredeweg SW, Postema K, Van den Heuvel ER, Hijmans JM, Sobhani S. Running with a minimalist shoe increases plantar pressure in the forefoot region of healthy female runners. J Sci Med Sport. 2015 Jul; 18(4):463-8. PMID: 25024135; DOI: 10.1016/j.jsams.2014.06.007;

de Boer MK, Oolders JM, van den Heuvel ER, Wiersma D, Schoevers RA, Knegtering H. Efficacy of tadalafil on erectile dysfunction in male patients using antipsychotics: a double-blind, placebo-controlled, crossover pilot study. J Clin Psychopharmacol. 2014 Jun; 34(3):380-2. PMID: 24743725; DOI: 10.1097/JCP.0000000000000113;

Darvishian M, Gefenaite G, Turner RM, Pechlivanoglou P, Van der Hoek W, Van den Heuvel ER, Hak E. After adjusting for bias in meta-analysis seasonal influenza vaccine remains effective in community-dwelling elderly. J Clin Epidemiol. 2014 Jul; 67(7):734-44. PMID: 24768004; DOI: 10.1016/j.jclinepi.2014.02.009;

Riese H, van den Heuvel ER, Snieder H, den Dunnen WF, Plosch T, Kema IP, Niezen-Koning KE. Association between methylation of the SLC6A4 promoter region in peripheral blood leukocytes and methylation in amygdala tissue. Psychosom Med. 2014 Apr; 76(3):244-6. PMID: 24632895; DOI: 10.1097/PSY.0000000000000048;

Lanting R, Broekstra DC, Werker PM, van den Heuvel ER. A systematic review and meta-analysis on the prevalence of Dupuytren disease in the general population of Western countries. Plast Reconstr Surg. 2014 Mar; 133(3):593-603. PMID: 24263394; PMCID: PMC7121457; DOI: 10.1097/01.prs.0000438455.37604.0f;

Demetrashvili N, Wit EC, van den Heuvel ER. Confidence intervals for intraclass correlation coefficients in variance components models. Stat Methods Med Res. 2016 10; 25(5):2359-2376. PMID: 24535554; DOI: 10.1177/0962280214522787;

Sobhani S, Zwerver J, van den Heuvel E, Postema K, Dekker R, Hijmans JM. Rocker shoes reduce Achilles tendon load in running and walking in patients with chronic Achilles tendinopathy. J Sci Med Sport. 2015 Mar; 18(2):133-8. PMID: 24636129; DOI: 10.1016/j.jsams.2014.02.008;

Zhan Z, van den Heuvel ER, Doornbos PM, Burger H, Verberne CJ, Wiggers T, de Bock GH. Strengths and weaknesses of a stepped wedge cluster randomized design: its application in a colorectal cancer follow-up study. J Clin Epidemiol. 2014 Apr; 67(4):454-61. PMID: 24491793; DOI: 10.1016/j.jclinepi.2013.10.018;

Almalik O, Nijhuis MB, van den Heuvel ER. Combined statistical analyses for long-term stability data with multiple storage conditions: a simulation study. J Biopharm Stat. 2014; 24(3):493-506. PMID: 24697656; DOI: 10.1080/10543406.2014.888439;

Demetrashvili N, Van den Heuvel ER, Wit EC. Probability genotype imputation method and integrated weighted lasso for QTL identification. BMC Genet. 2013 Dec 30; 14:125. PMID: 24378210; PMCID: PMC4126192; DOI: 10.1186/1471-2156-14-125;

den Dekker MA, Zwiers M, van den Heuvel ER, de Vos LC, Smit AJ, Zeebregts CJ, Oudkerk M, Vliegenthart R, Lefrandt JD, Mulder DJ. Skin autofluorescence, a non-invasive marker for AGE accumulation, is associated with the degree of atherosclerosis. PLoS One. 2013; 8(12):e83084. PMID: 24376641; PMCID: PMC3871581; DOI: 10.1371/journal.pone.0083084;

Seggers J, Haadsma ML, La Bastide-Van Gemert S, Heineman MJ, Middelburg KJ, Roseboom TJ, Schendelaar P, Van den Heuvel ER, Hadders-Algra M. Is ovarian hyperstimulation associated with higher blood pressure in 4-year-old IVF offspring? Part I: multivariable regression analysis. Hum Reprod. 2014 Mar; 29(3):502-9. PMID: 24365797; DOI: 10.1093/humrep/det396;

La Bastide-Van Gemert S, Seggers J, Haadsma ML, Heineman MJ, Middelburg KJ, Roseboom TJ, Schendelaar P, Hadders-Algra M, Van den Heuvel ER. Is ovarian hyperstimulation associated with higher blood pressure in 4-year-old IVF offspring? Part II: an explorative causal inference approach. Hum Reprod. 2014 Mar; 29(3):510-7. PMID: 24365798; DOI: 10.1093/humrep/det448;

Bocca G, Corpeleijn E, van den Heuvel ER, Stolk RP, Sauer PJ. Three-year follow-up of 3-year-old to 5-year-old children after participation in a multidisciplinary or a usual-care obesity treatment program. Clin Nutr. 2014 Dec; 33(6):1095-100. PMID: 24377413; DOI: 10.1016/j.clnu.2013.12.002;

Sobhani S, van den Heuvel E, Bredeweg S, Kluitenberg B, Postema K, Hijmans JM, Dekker R. Effect of rocker shoes on plantar pressure pattern in healthy female runners. Gait Posture. 2014 Mar; 39(3):920-5. PMID: 24370440

la Bastide-van Gemert S, Stolk RP, van den Heuvel ER, Fidler V. Causal inference algorithms can be useful in life course epidemiology. J Clin Epidemiol. 2014 Feb; 67(2):190-8. PMID: 24275501; DOI: 10.1016/j.jclinepi.2013.07.019;

Nguyen HT, Pham HT, Vo DK, Nguyen TD, van den Heuvel ER, Haaijer-Ruskamp FM, Taxis K. The effect of a clinical pharmacist-led training programme on intravenous medication errors: a controlled before and after study. BMJ Qual Saf. 2014 Apr; 23(4):319-24. PMID: 24195894; DOI: 10.1136/bmjqs-2013-002357;

Wessel SW, Chen Y, Maitra A, van den Heuvel ER, Slomp AM, Busscher HJ, van der Mei HC. Adhesion forces and composition of planktonic and adhering oral microbiomes. J Dent Res. 2014 Jan; 93(1):84-8. PMID: 24186560; PMCID: PMC3872853; DOI: 10.1177/0022034513511822;

Kikkert HK, de Jong C, van den Heuvel ER, Hadders-Algra M. Minor neurological dysfunction and behaviour in 9-year-old children born at term: evidence for sex dimorphism. Dev Med Child Neurol. 2013 Nov; 55(11):1023-9. PMID: 24098995; DOI: 10.1111/dmcn.12265;

Mzolo T, Hendriks M, van den Heuvel E. A comparison of statistical methods for combining relative bioactivities from parallel line bioassays. Pharm Stat. 2013 Nov-Dec; 12(6):375-84. PMID: 24123711

Lako IM, van den Heuvel ER, Knegtering H, Bruggeman R, Taxis K. Estimating dopamine D2 receptor occupancy for doses of 8 antipsychotics: a meta-analysis. J Clin Psychopharmacol. 2013 Oct; 33(5):675-81. PMID: 23948784

den Dekker MA, Takashima R, van den Heuvel ER, van den Dungen JJ, Tio RA, Oudkerk M, Vliegenthart R. Relationship between epicardial adipose tissue and subclinical coronary artery disease in patients with extra-cardiac arterial disease. Obesity (Silver Spring). 2014 Jan; 22(1):72-8. PMID: 23804361

de Boer MK, Castelein S, Bous J, van den Heuvel ER, Wiersma D, Schoevers RA, Knegtering H. The Antipsychotics and Sexual Functioning Questionnaire (ASFQ): preliminary evidence for reliability and validity. Schizophr Res. 2013 Nov; 150(2-3):410-5. PMID: 24064182; DOI: 10.1016/j.schres.2013.08.037;

La Bastide-Van Gemert S, van den Heuvel E. Exploring causal hypotheses: breaking with long-standing research traditions. Dev Med Child Neurol. 2013 Nov; 55(11):975-6. PMID: 24001028

Seggers J, Haadsma ML, Bastide-van Gemert Sl, Heineman MJ, Kok JH, Middelburg KJ, Roseboom TJ, Schendelaar P, Van den Heuvel ER, Hadders-Algra M. Blood pressure and anthropometrics of 4-y-old children born after preimplantation genetic screening: follow-up of a unique, moderately sized, randomized controlled trial. Pediatr Res. 2013 Nov; 74(5):606-14. PMID: 23949731

Bantema-Joppe EJ, van den Heuvel ER, de Munck L, de Bock GH, Smit WG, Timmer PR, Dolsma WV, Jansen L, Schröder CP, Siesling S, Langendijk JA, Maduro JH. Impact of primary local treatment on the development of distant metastases or death through locoregional recurrence in young breast cancer patients. Breast Cancer Res Treat. 2013 Aug; 140(3):577-85. PMID: 23912958

Lanting R, van den Heuvel ER, Westerink B, Werker PM. Prevalence of Dupuytren disease in The Netherlands. Plast Reconstr Surg. 2013 Aug; 132(2):394-403. PMID: 23897337

Bolster MA, Zöphel OT, van den Heuvel ER, Ruettermann M. Cubital tunnel syndrome: a comparison of an endoscopic technique with a minimal invasive open technique. J Hand Surg Eur Vol. 2014 Jul; 39(6):621-5. PMID: 23877730

van den Heuvel ER, Ijzerman-Boon PC. A comparison of test statistics for the recovery of rapid growth-based enumeration tests. Pharm Stat. 2013 Sep-Oct; 12(5):291-9. PMID: 23861331

Sobhani S, Hijmans J, van den Heuvel E, Zwerver J, Dekker R, Postema K. Biomechanics of slow running and walking with a rocker shoe. Gait Posture. 2013 Sep; 38(4):998-1004. PMID: 23770233

Sobhani S, Bredeweg S, Dekker R, Kluitenberg B, van den Heuvel E, Hijmans J, Postema K. Rocker shoe, minimalist shoe, and standard running shoe: a comparison of running economy. J Sci Med Sport. 2014 May; 17(3):312-6. PMID: 23711621

Quee PJ, Alizadeh BZ, Aleman A, van den Heuvel ER. Cognitive subtypes in non-affected siblings of schizophrenia patients: characteristics and profile congruency with affected family members. Psychol Med. 2014 Jan; 44(2):395-405. PMID: 23659373

Schendelaar P, Heineman KR, Heineman MJ, Jongbloed-Pereboom M, La Bastide-Van Gemert S, Middelburg KJ, Van den Heuvel ER, Hadders-Algra M. Movement variation in infants born following IVF/ICSI with and without ovarian hyperstimulation. Early Hum Dev. 2013 Jul; 89(7):507-13. PMID: 23582573

Lako IM, Bruggeman R, Liemburg EJ, van den Heuvel ER, Knegtering H, Slooff CJ, Wiersma D, Taxis K. A brief version of the Subjects' Response to Antipsychotics questionnaire to evaluate treatment effects. Schizophr Res. 2013 Jun; 147(1):175-180. PMID: 23561295

Schendelaar P, Middelburg KJ, Bos AF, Heineman MJ, Kok JH, La Bastide-Van Gemert S, Seggers J, Van den Heuvel ER, Hadders-Algra M. The effect of preimplantation genetic screening on neurological, cognitive and behavioural development in 4-year-old children: follow-up of a RCT. Hum Reprod. 2013 Jun; 28(6):1508-18. PMID: 23535872

Heineman KR, Middelburg KJ, Bos AF, Eidhof L, La Bastide-Van Gemert S, Van Den Heuvel ER, Hadders-Algra M. Reliability and concurrent validity of the Infant Motor Profile. Dev Med Child Neurol. 2013 Jun; 55(6):539-45. PMID: 23480426

Tjon Pian Gi RE, Ilmarinen T, van den Heuvel ER, Aaltonen LM, Andersen J, Brunings JW, Chirila M, Dietz A, Ferran Vilà F, Friedrich G, de Gier HH, Golusinski W, Graupp M, Hantzakos A, Horcasitas R, Jackowska J, Koelmel JC, Lawson G, Lindner F, Remacle M, Sittel C, Weichbold V, Wierzbicka M, Dikkers FG. Safety of intralesional cidofovir in patients with recurrent respiratory papillomatosis: an international retrospective study on 635 RRP patients. Eur Arch Otorhinolaryngol. 2013 May; 270(5):1679-87. PMID: 23377227

Schneeberger C, van den Heuvel ER, Erwich JJ, Stolk RP, Visser CE, Geerlings SE. Contamination rates of three urine-sampling methods to assess bacteriuria in pregnant women. Obstet Gynecol. 2013 Feb; 121(2 Pt 1):299-305. PMID: 23344279

Muszanska AK, Nejadnik MR, Chen Y, van den Heuvel ER, Busscher HJ, van der Mei HC, Norde W. Bacterial adhesion forces with substratum surfaces and the susceptibility of biofilms to antibiotics. Antimicrob Agents Chemother. 2012 Sep; 56(9):4961-4. PMID: 22733073; PMCID: PMC3421903; DOI: 10.1128/AAC.00431-12;

Younes JA, van der Mei HC, van den Heuvel E, Busscher HJ, Reid G. Adhesion forces and coaggregation between vaginal staphylococci and lactobacilli. PLoS One. 2012; 7(5):e36917. PMID: 22629342; PMCID: PMC3356358; DOI: 10.1371/journal.pone.0036917;

Tjon Pian Gi RE, Halmos GB, van Hemel BM, van den Heuvel ER, van der Laan BF, Plaat BE, Dikkers FG. Narrow band imaging is a new technique in visualization of recurrent respiratory papillomatosis. Laryngoscope. 2012 Aug; 122(8):1826-30. PMID: 22566012

Beetz I, Schilstra C, van der Schaaf A, van den Heuvel ER, Doornaert P, van Luijk P, Vissink A, van der Laan BF, Leemans CR, Bijl HP, Christianen ME, Steenbakkers RJ, Langendijk JA. NTCP models for patient-rated xerostomia and sticky saliva after treatment with intensity modulated radiotherapy for head and neck cancer: the role of dosimetric and clinical factors. Radiother Oncol. 2012 Oct; 105(1):101-6. PMID: 22516776

Chedoe I, Molendijk H, Hospes W, Van den Heuvel ER, Taxis K. The effect of a multifaceted educational intervention on medication preparation and administration errors in neonatal intensive care. Arch Dis Child Fetal Neonatal Ed. 2012 Nov; 97(6):F449-55. PMID: 22491014

Brouwer CL, Steenbakkers RJ, van den Heuvel E, Duppen JC, Navran A, Bijl HP, Chouvalova O, Burlage FR, Meertens H, Langendijk JA, van 't Veld AA. 3D Variation in delineation of head and neck organs at risk. Radiat Oncol. 2012 Mar 13; 7:32. PMID: 22414264; PMCID: PMC3337234; DOI: 10.1186/1748-717X-7-32;

Beetz I, Schilstra C, van Luijk P, Christianen ME, Doornaert P, Bijl HP, Chouvalova O, van den Heuvel ER, Steenbakkers RJ, Langendijk JA. External validation of three dimensional conformal radiotherapy based NTCP models for patient-rated xerostomia and sticky saliva among patients treated with intensity modulated radiotherapy. Radiother Oncol. 2012 Oct; 105(1):94-100. PMID: 22169766

van Kessel G, Geels MJ, de Weerd S, Buijs LJ, de Bruijni MA, Glansbeek HL, van den Bosch JF, Heldens JG, van den Heuvel ER. Development and qualification of the parallel line model for the estimation of human influenza haemagglutinin content using the single radial immunodiffusion assay. Vaccine. 2012 Jan 05; 30(2):201-9. PMID: 22107849

Verdonk GP, Willemse MJ, Hoefs SG, Cremers G, van den Heuvel ER. The Most Probable Limit of Detection (MPL) for rapid microbiological methods. J Microbiol Methods. 2010 Sep; 82(3):193-7. PMID: 20470835

van den Heuvel E. Estimation of the limit of detection for quantal response bioassays. Pharm Stat. 2011 May-Jun; 10(3):203-12. PMID: 21574241

van den Heuvel E, Starreveld JS, de Ru M, Krauwer V, Versteegh FG. Somatic and psychiatric co-morbidity in children with attention deficit hyperactivity disorder. Acta Paediatr. 2007 Mar; 96(3):454-6. PMID: 17407478

Visser JA, Durlinger AL, Peters IJ, van den Heuvel ER, Rose UM, Kramer P, de Jong FH, Themmen AP. Increased oocyte degeneration and follicular atresia during the estrous cycle in anti-Müllerian hormone null mice. Endocrinology. 2007 May; 148(5):2301-8. PMID: 17255205

Nijhuis MB, van den Heuvel ER. Closed-form confidence intervals on measures of precision for an interlaboratory study. J Biopharm Stat. 2007; 17(1):123-42. PMID: 17219759

De Backer AI, Mortelé KJ, Van Den Heuvel E, Vanschoubroeck IJ, Kockx MM, Van de Vyvere M. Tuberculous adenitis: comparison of CT and MRI findings with histopathological features. Eur Radiol. 2007 Apr; 17(4):1111-7. PMID: 17180329

Vaes BL, Ducy P, Sijbers AM, Hendriks JM, van Someren EP, de Jong NG, van den Heuvel ER, Olijve W, van Zoelen EJ, Dechering KJ. Microarray analysis on Runx2-deficient mouse embryos reveals novel Runx2 functions and target genes during intramembranous and endochondral bone formation. Bone. 2006 Oct; 39(4):724-38. PMID: 16774856

Stessels F, Van den Eynden G, Van der Auwera I, Salgado R, Van den Heuvel E, Harris AL, Jackson DG, Colpaert CG, van Marck EA, Dirix LY, Vermeulen PB. Breast adenocarcinoma liver metastases, in contrast to colorectal cancer liver metastases, display a non-angiogenic growth pattern that preserves the stroma and lacks hypoxia. Br J Cancer. 2004 Apr 05; 90(7):1429-36. PMID: 15054467

Visser M, van den Heuvel E, Deurenberg P. Prediction equations for the estimation of body composition in the elderly using anthropometric data. Br J Nutr. 1994 Jun; 71(6):823-33. PMID: 8031732

Westerterp-Plantenga MS, Van den Heuvel E, Wouters L, Ten Hoor F. Diet-induced thermogenesis and cumulative food intake curves as a function of familiarity with food and dietary restraint in humans. Physiol Behav. 1992 Mar; 51(3):457-65. PMID: 1523221

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 222 publications over 21 distinct years, with a maximum of 32 publications in 2014

Bar chart showing 222 publications over 21 distinct years, with a maximum of 32 publications in 2014

Year	Publications
1992	1
1994	1
2004	1
2006	2
2007	3
2010	2
2011	2
2012	6
2013	29
2014	32
2015	17
2016	23
2017	16
2018	17
2019	16
2020	13
2021	7
2022	10
2023	9
2024	10
2025	5

2014 BMJ Quality and Safety: Best paper award

Contact for Mentoring:

617.358.2734

Download vCard

Van Den Heuvel's Networks

Click the "See All" links for more information and interactive visualizations

Concepts

See all (754) concept(s)

Co-Authors

See all (4) people

Similar People

See all (60) people

Same Department

Search Department