Vanessa Xanthakis, PhD
Associate Professor
Boston University Chobanian & Avedisian School of Medicine
Medicine
Preventive Medicine & Epidemiology

PhD, Boston University School of Public Health
MS, University of Athens
BS, University of Athens



Dr. Vanessa Xanthakis is a biostatistician with training in applied mathematics and statistics, and has a strong commitment to clinical epidemiological research. Presently, she is an Assistant Professor in the Section of Preventive Medicine and Epidemiology in the Department of Medicine at Chobanian and Avedisian School of Medicine and in the Biostatistics Department at Boston University School of Public Health. She is an investigator at the Framingham Heart Study and serves as the biostatistician on several investigations. She also serves as the Program Director for the Boston University T32 Program in Cardiovascular Epidemiology and the Promotion of Research In MEdical Residency (R38) program. She is the Director of Research Training for the Section of Preventive Medicine and Epidemiology. For the last 12 years, Dr. Xanthakis has focused her research on:

A) the epidemiology of cardiac remodeling and subclinical disease, including identifying cardiovascular disease risk factors;

B) population-based vascular testing and echocardiography, including identifying biological, environmental, and genetic determinants (correlates) of cardiac structure and function;

C) epidemiology of novel biomarkers including but not limited to natriuretic peptides, adipokines, and vascular growth factors;

D) cardiovascular risk prediction using biomarkers and assessing their incremental prognostic utility (focus of her PhD thesis);

E) epidemiology of heart failure and its precursors; and

F) ideal cardiovascular health and its impact on cardiovascular disease and its precursors.

Associate Professor
Boston University School of Public Health
Biostatistics


Investigator
Framingham Heart Study


Member
Boston University
Evans Center for Interdisciplinary Biomedical Research




Molecular Determinants of Atherosclerotic Cardiovascular Disease in Multi-ethnic Populations
04/01/2023 - 03/31/2027 (Subcontract PI)
The University Of Texas Health Science Center At Houston NIH NHLBI
1R01HL168683-01

Epidemiology of Blood Pressure Responses to Perturbation
09/01/2022 - 02/28/2027 (Subcontract PI)
University of Texas Health Science Center at San Antonio NIH NIA
7R01AG075703-02

Improving Blood Pressure Screening and Treatment Strategies in Young Adults
07/01/2021 - 05/31/2026 (Subcontract PI)
Kaiser Foundation Research Institute, a division of Kaiser Foundation Hospitals NIH NHLBI
5R01HK158790-02

Multidisciplinary Training Program in Cardiovascular Epidemiology
04/01/2021 - 03/31/2026 (PI)
NIH/National Heart, Lung, and Blood Institute
5T32HL125232-08

Myocardial Radiomics and Mechanics in the Pathology and Prognosis of Cardiovascular Disease
03/15/2021 - 02/28/2026 (Subcontract PI)
Beth Israel Deaconess Medical Center, Inc NIH NHLBI
5R01HL155717-02

Characterization of Functional Iron Deficiency and Repletion in Heart Failure with Preserved Ejection Fraction
08/15/2021 - 06/30/2025 (Subcontract PI)
The General Hospital Corporation d/b/a Massachusetts General Hospital NIH NHLBI
5R01HL159514-02

Racial/Ethnic Disparities in Heart Failure: A Cross-Cohort Collaboration
04/01/2021 - 03/31/2025 (Subcontract PI)
Kent County Memorial Hospital NIH NHLBI
5R01HL150170-02

PRIMER: Promoting Research In MEdical Residency
07/01/2020 - 06/30/2024 (PI)
NIH/National Heart, Lung, and Blood Institute
5R38HL143584-04

Plasma Proteome and Risk of Alzheimer Dementia and Related Endophenotypes in the Framingham Study
09/01/2022 - 03/31/2024 (Subcontract PI)
University of Texas Health Science Center at San Antonio NIH NIA
7RF1AG063507-02

Characterization of Molecular and Physiologic Signatures of Impaired Multi-Organ System Reserve Capacity During Exercise in Heart Failure with Preserved Ejection Fraction
04/01/2020 - 03/31/2024 (Subcontract PI)
Massachusetts General Hospital NIH NHLBI
5R01HL151841-03

Showing 10 of 17 results. Show All Results


Title


Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Mitchell GF, Rong J, Larson MG, Cooper LL, Xanthakis V, Benjamin EJ, Hamburg NM, Vasan RS. Longitudinal Hemodynamic Correlates of and Sex Differences in the Evolution of Blood Pressure Across the Adult Lifespan: The Framingham Heart Study. J Am Heart Assoc. 2023 Jun 20; 12(12):e027329.View Related Profiles. PMID: 37318016; PMCID: PMC10356050; DOI: 10.1161/JAHA.122.027329;
     
  2. Li Y, Gray A, Xue L, Farb MG, Ayalon N, Andersson C, Ko D, Benjamin EJ, Levy D, Vasan RS, Larson MG, Rong J, Xanthakis V, Liu C, Fetterman JL, Gopal DM. Metabolomic Profiles, Ideal Cardiovascular Health, and Risk of Heart Failure and Atrial Fibrillation: Insights From the Framingham Heart Study. J Am Heart Assoc. 2023 Jun 20; 12(12):e028022.View Related Profiles. PMID: 37301766; PMCID: PMC10356055; DOI: 10.1161/JAHA.122.028022;
     
  3. Mi MY, Gajjar P, Walker ME, Miller P, Xanthakis V, Murthy VL, Larson MG, Vasan RS, Shah RV, Lewis GD, Nayor M. Association of healthy dietary patterns and cardiorespiratory fitness in the community. Eur J Prev Cardiol. 2023 Apr 28.View Related Profiles. PMID: 37164358
     
  4. Lin H, Kwan AC, Castro-Diehl C, Short MI, Xanthakis V, Yola IM, Salto G, Mitchell GF, Larson MG, Vasan RS, Cheng S. Sex-specific differences in the genetic and environmental effects on cardiac phenotypic variation assessed by echocardiography. Sci Rep. 2023 Apr 08; 13(1):5786.View Related Profiles. PMID: 37031215; PMCID: PMC10082757; DOI: 10.1038/s41598-023-32577-6;
     
  5. Mi MY, Gajjar P, Walker ME, Miller P, Xanthakis V, Murthy VL, Larson MG, Vasan RS, Shah RV, Lewis GD, Nayor M. Association of Healthy Dietary Patterns and Cardiorespiratory Fitness in the Community. medRxiv. 2023 Feb 10.View Related Profiles. PMID: 36798343; PMCID: PMC9934801; DOI: 10.1101/2023.02.09.23285714;
     
  6. Liu X, Pan S, Xanthakis V, Vasan RS, Psaty BM, Austin TR, Newman AB, Sanders JL, Wu C, Tracy RP, Gerszten RE, Odden MC. Plasma proteomic signature of decline in gait speed and grip strength. Aging Cell. 2022 Dec; 21(12):e13736. PMID: 36333824; PMCID: PMC9741503; DOI: 10.1111/acel.13736;
     
  7. Kwan A, Demosthenes E, Salto G, Ouyang D, Nguyen T, Nwabuo CC, Luong E, Hoang A, Osypiuk E, Stantchev P, Kim EH, Hiremath P, Li D, Vasan R, Xanthakis V, Cheng S. Cardiac microstructural alterations measured by echocardiography identify sex-specific risk for heart failure. Heart. 2022 Oct 28; 108(22):1800-1806.View Related Profiles. PMID: 35680379; PMCID: PMC9626911; DOI: 10.1136/heartjnl-2022-320876;
     
  8. Hermann EA, Lee B, Balte PP, Xanthakis V, Kirkpatrick BD, Cushman M, Oelsner E. Association of Symptoms After COVID-19 Vaccination With Anti-SARS-CoV-2 Antibody Response in the Framingham Heart Study. JAMA Netw Open. 2022 Oct 03; 5(10):e2237908. PMID: 36269359; PMCID: PMC9587476; DOI: 10.1001/jamanetworkopen.2022.37908;
     
  9. Oelsner EC, Krishnaswamy A, Balte PP, Allen NB, Ali T, Anugu P, Andrews HF, Arora K, Asaro A, Barr RG, Bertoni AG, Bon J, Boyle R, Chang AA, Chen G, Coady S, Cole SA, Coresh J, Cornell E, Correa A, Couper D, Cushman M, Demmer RT, Elkind MSV, Folsom AR, Fretts AM, Gabriel KP, Gallo LC, Gutierrez J, Han MLK, Henderson JM, Howard VJ, Isasi CR, Jacobs DR, Judd SE, Mukaz DK, Kanaya AM, Kandula NR, Kaplan RC, Kinney GL, Kucharska-Newton A, Lee JS, Lewis CE, Levine DA, Levitan EB, Levy BD, Make BJ, Malloy K, Manly JJ, Mendoza-Puccini C, Meyer KA, Min YN, Moll MR, Moore WC, Mauger D, Ortega VE, Palta P, Parker MM, Phipatanakul W, Post WS, Postow L, Psaty BM, Regan EA, Ring K, Roger VL, Rotter JI, Rundek T, Sacco RL, Schembri M, Schwartz DA, Seshadri S, Shikany JM, Sims M, Hinckley Stukovsky KD, Talavera GA, Tracy RP, Umans JG, Vasan RS, Watson KE, Wenzel SE, Winters K, Woodruff PG, Xanthakis V, Zhang Y, Zhang Y. Collaborative Cohort of Cohorts for COVID-19 Research (C4R) Study: Study Design. Am J Epidemiol. 2022 Jun 27; 191(7):1153-1173.View Related Profiles. PMID: 35279711; PMCID: PMC8992336; DOI: 10.1093/aje/kwac032;
     
  10. Rade JJ, Barton BA, Vasan RS, Kronsberg SS, Xanthakis V, Keaney JF, Hamburg NM, Kakouros N, Kickler TA. Association of Thromboxane Generation With Survival in Aspirin Users and Nonusers. J Am Coll Cardiol. 2022 Jul 19; 80(3):233-250.View Related Profiles. PMID: 35660296
     
Showing 10 of 134 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 133 publications over 19 distinct years, with a maximum of 20 publications in 2020

YearPublications
19991
20022
20071
20081
20095
20108
20113
20128
20137
20146
20155
20166
20176
20187
20199
202020
202119
202214
20235


AHA News: Overcoming Midlife Barriers to Exercise and Better Health

U.S. News & World Report 6/9/2021

AHA News: Overcoming Midlife Barriers to Exercise and Better Health

Drugs.com 6/9/2021

Healthy diet, exercise might be key to achieving optimal health in later years

HealthWorld 4/3/2021

Exercise, Healthy Diet in Midlife May Prevent Serious Health Conditions in Senior Years

Pharmacy Times 4/2/2021

Research shows how midlife diet, exercise can help in older adulthood

AJC 4/1/2021

Healthy Living in Middle Age Really Pays Off in Senior Years

HealthDay 3/31/2021

Study: Plant-Based Diets Improve Cardiac Function, Cognitive Health

Pharmacy Times 3/5/2021

Plant-based diet high in certain foods protects brain and heart

Slash Gear 3/5/2021

MIND diet, a combination of Mediterranean and DASH diets, associated with cardiac and cognitive benefits

Cardiovascular Business 2/26/2021

Research Suggests This Pair Of Superfood Families May Support Improved Heart & Brain Health

Mind Body Green 2/26/2021

Increased Blood Pressure During Exercise Could Predict Risk of CVD, Death

MD Magazine 5/20/2020

Ideal CV Health Over the Long Term Linked With Better Survival, Less Disease

tctMD 3/15/2020

The Longer You Follow a Healthier Lifestyle in Middle-Age The Lower Your Risk of Death Later in Life

Yahoo News 3/12/2020
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Biomarkers
Biostatistics
Epidemiology
Heart Failure
Multilevel modeling
Risk prediction
Screening
Ventricular remodeling

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