Vanessa Xanthakis, PhD
Associate Professor
Boston University Chobanian & Avedisian School of Medicine
Medicine
Preventive Medicine & Epidemiology

PhD, Boston University School of Public Health
MS, University of Athens
BS, University of Athens



Dr. Vanessa Xanthakis is a biostatistician with training in applied mathematics and statistics, and has a strong commitment to clinical epidemiological research. Presently, she is an Assistant Professor in the Section of Preventive Medicine and Epidemiology in the Department of Medicine at Chobanian and Avedisian School of Medicine and in the Biostatistics Department at Boston University School of Public Health. She is an investigator at the Framingham Heart Study and serves as the biostatistician on several investigations. She also serves as the Program Director for the Boston University T32 Program in Cardiovascular Epidemiology and the Promotion of Research In MEdical Residency (R38) program. She is the Director of Research Training for the Section of Preventive Medicine and Epidemiology. For the last 12 years, Dr. Xanthakis has focused her research on:

A) the epidemiology of cardiac remodeling and subclinical disease, including identifying cardiovascular disease risk factors;

B) population-based vascular testing and echocardiography, including identifying biological, environmental, and genetic determinants (correlates) of cardiac structure and function;

C) epidemiology of novel biomarkers including but not limited to natriuretic peptides, adipokines, and vascular growth factors;

D) cardiovascular risk prediction using biomarkers and assessing their incremental prognostic utility (focus of her PhD thesis);

E) epidemiology of heart failure and its precursors; and

F) ideal cardiovascular health and its impact on cardiovascular disease and its precursors.

Associate Professor
Boston University School of Public Health
Biostatistics


Investigator
Framingham Heart Study


Member
Boston University
Evans Center for Interdisciplinary Biomedical Research




Molecular Determinants of Atherosclerotic Cardiovascular Disease in Multi-ethnic Populations
04/01/2023 - 03/31/2027 (Subcontract PI)
The University Of Texas Health Science Center At Houston NIH NHLBI
1R01HL168683-01

Epidemiology of Blood Pressure Responses to Perturbation
09/01/2022 - 02/28/2027 (Subcontract PI)
University of Texas Health Science Center at San Antonio NIH NIA
7R01AG075703-02

Improving Blood Pressure Screening and Treatment Strategies in Young Adults
07/01/2021 - 05/31/2026 (Subcontract PI)
Kaiser Foundation Research Institute, a division of Kaiser Foundation Hospitals NIH NHLBI
5R01HK158790-02

Multidisciplinary Training Program in Cardiovascular Epidemiology
04/01/2021 - 03/31/2026 (PI)
NIH/National Heart, Lung, and Blood Institute
5T32HL125232-08

Myocardial Radiomics and Mechanics in the Pathology and Prognosis of Cardiovascular Disease
03/15/2021 - 02/28/2026 (Subcontract PI)
Beth Israel Deaconess Medical Center, Inc NIH NHLBI
5R01HL155717-02

Characterization of Functional Iron Deficiency and Repletion in Heart Failure with Preserved Ejection Fraction
08/15/2021 - 06/30/2025 (Subcontract PI)
The General Hospital Corporation d/b/a Massachusetts General Hospital NIH NHLBI
5R01HL159514-02

Racial/Ethnic Disparities in Heart Failure: A Cross-Cohort Collaboration
04/01/2021 - 03/31/2025 (Subcontract PI)
Kent County Memorial Hospital NIH NHLBI
5R01HL150170-02

PRIMER: Promoting Research In MEdical Residency
07/01/2020 - 06/30/2024 (PI)
NIH/National Heart, Lung, and Blood Institute
5R38HL143584-04

Plasma Proteome and Risk of Alzheimer Dementia and Related Endophenotypes in the Framingham Study
09/01/2022 - 03/31/2024 (Subcontract PI)
University of Texas Health Science Center at San Antonio NIH NIA
7RF1AG063507-02

Characterization of Molecular and Physiologic Signatures of Impaired Multi-Organ System Reserve Capacity During Exercise in Heart Failure with Preserved Ejection Fraction
04/01/2020 - 03/31/2024 (Subcontract PI)
Massachusetts General Hospital NIH NHLBI
5R01HL151841-03

Showing 10 of 17 results. Show All Results


Title


Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Barton BA, Kronsberg SS, Hariri E, Vasan RS, Rade GA, Xanthakis V, Kickler TS, Rade JJ. Adjustment for Renal Function Improves the Prognostic Performance of Urinary Thromboxane Metabolites. Clin Chem. 2024 Apr 03; 70(4):660-668. PMID: 38416712
     
  2. An J, Fischer H, Ni L, Xia M, Choi SK, Morrissette KL, Wei R, Reynolds K, Muntner P, Safford MM, Moran AE, Bellows BK, Isasi CR, Allen NB, Xanthakis V, Colantonio LD, Zhang Y. Association Between Young Adult Characteristics and Blood Pressure Trajectories. J Am Heart Assoc. 2024 Apr 02; e033053. PMID: 38563367
     
  3. Kim JS, Sun Y, Balte P, Cushman M, Boyle R, Tracy RP, Styer LM, Bell TD, Anderson MR, Allen NB, Schreiner PJ, Bowler RP, Schwartz DA, Lee JS, Xanthakis V, Doyle MF, Regan EA, Make BJ, Kanaya AM, Wenzel SE, Coresh J, Isasi CR, Raffield LM, Elkind MSV, Howard VJ, Ortega VE, Woodruff P, Cole SA, Henderson JM, Mantis NJ, Parker MM, Demmer RT, Oelsner EC. Demographic and Clinical Factors Associated With SARS-CoV-2 Spike 1 Antibody Response Among Vaccinated US Adults: the C4R Study. Nat Commun. 2024 Feb 19; 15(1):1492. PMID: 38374032; PMCID: PMC10876680; DOI: 10.1038/s41467-024-45468-9;
     
  4. Rempakos A, Prescott B, Mitchell GF, Vasan RS, Xanthakis V. Association of Life's Essential 8 With Cardiovascular Disease and Mortality: The Framingham Heart Study. J Am Heart Assoc. 2023 Dec 05; 12(23):e030764. PMID: 38014669; PMCID: PMC10727315; DOI: 10.1161/JAHA.123.030764;
     
  5. Mitchell GF, Rong J, Larson MG, Korzinski TJ, Xanthakis V, Sigurdsson S, Gudnason V, Launer LJ, Aspelund T, Hamburg NM, Gotal JD, Vasan RS. Vascular Age Assessed From an Uncalibrated, Noninvasive Pressure Waveform by Using a Deep Learning Approach: The AI-VascularAge Model. Hypertension. 2024 Jan; 81(1):193-201.View Related Profiles. PMID: 37901957; PMCID: PMC10842456; DOI: 10.1161/HYPERTENSIONAHA.123.21638;
     
  6. Mi MY, Gajjar P, Walker ME, Miller P, Xanthakis V, Murthy VL, Larson MG, Vasan RS, Shah RV, Lewis GD, Nayor M. Association of healthy dietary patterns and cardiorespiratory fitness in the community. Eur J Prev Cardiol. 2023 Oct 10; 30(14):1450-1461.View Related Profiles. PMID: 37164358; PMCID: PMC10562138; DOI: 10.1093/eurjpc/zwad113;
     
  7. Mossavar-Rahmani Y, Lin J, Pan S, Song RJ, Xue X, Spartano NL, Xanthakis V, Sotres-Alvarez D, Marquez DX, Daviglus M, Carlson JA, Parada H, Evenson KR, Talavera AC, Gellman M, Perreira KM, Gallo LC, Vasan RS, Kaplan RC. Characterizing longitudinal change in accelerometry-based moderate-to-vigorous physical activity in the Hispanic Community Health Study/Study of Latinos and the Framingham Heart Study. BMC Public Health. 2023 Aug 24; 23(1):1614.View Related Profiles. PMID: 37620824; PMCID: PMC10464120; DOI: 10.1186/s12889-023-16442-9;
     
  8. Mitchell GF, Rong J, Larson MG, Cooper LL, Xanthakis V, Benjamin EJ, Hamburg NM, Vasan RS. Longitudinal Hemodynamic Correlates of and Sex Differences in the Evolution of Blood Pressure Across the Adult Lifespan: The Framingham Heart Study. J Am Heart Assoc. 2023 Jun 20; 12(12):e027329.View Related Profiles. PMID: 37318016; PMCID: PMC10356050; DOI: 10.1161/JAHA.122.027329;
     
  9. Li Y, Gray A, Xue L, Farb MG, Ayalon N, Andersson C, Ko D, Benjamin EJ, Levy D, Vasan RS, Larson MG, Rong J, Xanthakis V, Liu C, Fetterman JL, Gopal DM. Metabolomic Profiles, Ideal Cardiovascular Health, and Risk of Heart Failure and Atrial Fibrillation: Insights From the Framingham Heart Study. J Am Heart Assoc. 2023 Jun 20; 12(12):e028022.View Related Profiles. PMID: 37301766; PMCID: PMC10356055; DOI: 10.1161/JAHA.122.028022;
     
  10. Lin H, Kwan AC, Castro-Diehl C, Short MI, Xanthakis V, Yola IM, Salto G, Mitchell GF, Larson MG, Vasan RS, Cheng S. Sex-specific differences in the genetic and environmental effects on cardiac phenotypic variation assessed by echocardiography. Sci Rep. 2023 Apr 08; 13(1):5786.View Related Profiles. PMID: 37031215; PMCID: PMC10082757; DOI: 10.1038/s41598-023-32577-6;
     
Showing 10 of 140 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 139 publications over 20 distinct years, with a maximum of 20 publications in 2020

YearPublications
19991
20022
20071
20081
20095
20108
20113
20128
20137
20146
20155
20166
20176
20187
20199
202020
202119
202214
20238
20243


AHA News: Overcoming Midlife Barriers to Exercise and Better Health

U.S. News & World Report 6/9/2021

AHA News: Overcoming Midlife Barriers to Exercise and Better Health

Drugs.com 6/9/2021

Healthy diet, exercise might be key to achieving optimal health in later years

HealthWorld 4/3/2021

Exercise, Healthy Diet in Midlife May Prevent Serious Health Conditions in Senior Years

Pharmacy Times 4/2/2021

Research shows how midlife diet, exercise can help in older adulthood

AJC 4/1/2021

Healthy Living in Middle Age Really Pays Off in Senior Years

HealthDay 3/31/2021

Study: Plant-Based Diets Improve Cardiac Function, Cognitive Health

Pharmacy Times 3/5/2021

Plant-based diet high in certain foods protects brain and heart

Slash Gear 3/5/2021

MIND diet, a combination of Mediterranean and DASH diets, associated with cardiac and cognitive benefits

Cardiovascular Business 2/26/2021

Research Suggests This Pair Of Superfood Families May Support Improved Heart & Brain Health

Mind Body Green 2/26/2021

Increased Blood Pressure During Exercise Could Predict Risk of CVD, Death

MD Magazine 5/20/2020

Ideal CV Health Over the Long Term Linked With Better Survival, Less Disease

tctMD 3/15/2020

The Longer You Follow a Healthier Lifestyle in Middle-Age The Lower Your Risk of Death Later in Life

Yahoo News 3/12/2020
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Biomarkers
Biostatistics
Epidemiology
Heart Failure
Multilevel modeling
Risk prediction
Screening
Ventricular remodeling

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