Vanessa Xanthakis, PhD
Assistant Professor
Boston University School of Medicine
Dept of Medicine
Preventive Medicine & Epidemiology

PhD, Boston University School of Public Health
MS, University of Athens




Dr. Vanessa Xanthakis is a biostatistician with training in applied mathematics and statistics, and has a strong commitment to clinical epidemiological research. Presently, she is an Assistant Professor in the Section of Preventive Medicine and Epidemiology in the Department of Medicine at Boston University School of Medicine and in the Biostatistics Department at Boston University School of Public Health. She is an investigator at the Framingham Heart Study and serves as the biostatistician on several investigations. She also serves as the Program Director for the Boston University T32 Program in Cardiovascular Epidemiology and the Promotion of Research In MEdical Residency (R38) program. She is the Director of Research Training for the Section of Preventive Medicine and Epidemiology. For the last 12 years, Dr. Xanthakis has focused her research on:

A) the epidemiology of cardiac remodeling and subclinical disease, including identifying cardiovascular disease risk factors;

B) population-based vascular testing and echocardiography, including identifying biological, environmental, and genetic determinants (correlates) of cardiac structure and function;

C) epidemiology of novel biomarkers including but not limited to natriuretic peptides, adipokines, and vascular growth factors;

D) cardiovascular risk prediction using biomarkers and assessing their incremental prognostic utility (focus of her PhD thesis);

E) epidemiology of heart failure and its precursors; and

F) ideal cardiovascular health and its impact on cardiovascular disease and its precursors.

Assistant Professor
Boston University School of Public Health
Biostatistics


Investigator
Framingham Heart Study


Member
Boston University
Evans Center for Interdisciplinary Biomedical Research




Characterization of Functional Iron Deficiency and Repletion in Heart Failure with Preserved Ejection Fraction
08/15/2021 - 06/30/2025 (Subcontract PI)
The General Hospital Corporation d/b/a Massachusetts General Hospital NIH NHLBI
1R01HL159514-01

Racial/Ethnic Disparities in Heart Failure: A Cross-Cohort Collaboration
04/01/2021 - 03/31/2025 (Subcontract PI)
Kent County Memorial Hospital NIH NHLBI
1R01HL150170-01A1

Characterization of Molecular and Physiologic Signatures of Impaired Multi-Organ System Reserve Capacity During Exercise in Heart Failure with Preserved Ejection Fraction
04/01/2020 - 03/31/2024 (Subcontract PI)
Massachusetts General Hospital NIH NHLBI
5R01HL151841-02

Provider Agreement for Vanessa Xanthakis
12/14/2015 - 06/30/2016 (PI)
American Heart Association


Screening for Left Ventricular Dysfunction/Hypertrophy with Novel Biomarkers to Prevent Heart Failure
01/01/2013 - 12/31/2015 (PI)
American Heart Association


Plasma Nitrate: Clinical Correlates and Prognostic Significance
01/01/2012 - 12/31/2014 (PI)
University of Erlangen Nuremberg


Plasma Nitrate: Clinical Correlates and Prognostic Significance
01/01/2012 - 12/31/2012 (PI)
University of Erlangen Nuremberg




Title


Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Bourdillon MT, Gaye B, Song RJ, Vasan RS, Xanthakis V. Notable paradoxical phenomena in associations between cardiovascular health score, subclinical and clinical cardiovascular disease in the community: The Framingham Heart Study. PLoS One. 2022; 17(5):e0267267.View Related Profiles. PMID: 35511823; PMCID: PMC9070900; DOI: 10.1371/journal.pone.0267267;
     
  2. Shrout TA, Pan S, Mitchell GF, Vasan RS, Xanthakis V. Association of orthostatic blood pressure response with incident heart failure: The Framingham Heart Study. PLoS One. 2022; 17(4):e0267057.View Related Profiles. PMID: 35452474; PMCID: PMC9032405; DOI: 10.1371/journal.pone.0267057;
     
  3. Vasan RS, Enserro DM, Xanthakis V, Beiser AS, Seshadri S. Temporal Trends in the Remaining Lifetime Risk of Cardiovascular Disease Among Middle-Aged Adults Across 6 Decades: The Framingham Study. Circulation. 2022 Apr 26; 145(17):1324-1338.View Related Profiles. PMID: 35430874; PMCID: PMC9038688; DOI: 10.1161/CIRCULATIONAHA.121.057889;
     
  4. Oelsner EC, Krishnaswamy A, Balte PP, Allen NB, Ali T, Anugu P, Andrews H, Arora K, Asaro A, Barr RG, Bertoni AG, Bon J, Boyle R, Chang AA, Chen G, Coady S, Cole SA, Coresh J, Cornell E, Correa A, Couper D, Cushman M, Demmer RT, Elkind MSV, Folsom AR, Fretts AM, Gabriel KP, Gallo L, Gutierrez J, Han MLK, Henderson JM, Howard VJ, Isasi CR, Jacobs DR, Judd SE, Mukaz DK, Kanaya AM, Kandula NR, Kaplan R, Kinney GL, Kucharska-Newton A, Lee JS, Lewis CE, Levine DA, Levitan EB, Levy B, Make B, Malloy K, Manly JJ, Mendoza-Puccini C, Meyer KA, Min YI, Moll M, Moore WC, Mauger D, Ortega VE, Palta P, Parker MM, Phipatanakul W, Post WS, Postow L, Psaty BM, Regan EA, Ring K, Roger VL, Rotter JI, Rundek T, Sacco RL, Schembri M, Schwartz DA, Seshadri S, Shikany JM, Sims M, Hinckley Stukovsky KD, Talavera GA, Tracy RP, Umans JG, Vasan RS, Watson K, Wenzel SE, Winters K, Woodruff PG, Xanthakis V, Zhang Y, Zhang Y, C R Investigators FT. Collaborative Cohort of Cohorts for COVID-19 Research (C4R) Study: Study Design. Am J Epidemiol. 2022 Mar 12.View Related Profiles. PMID: 35279711
     
  5. Bourdillon MT, Song RJ, Musa Yola I, Xanthakis V, Vasan RS. Prevalence, Predictors, Progression, and Prognosis of Hypertension Subtypes in the Framingham Heart Study. J Am Heart Assoc. 2022 03 15; 11(6):e024202.View Related Profiles. PMID: 35261291
     
  6. Vasan RS, Pan S, Xanthakis V, Beiser A, Larson MG, Seshadri S, Mitchell GF. Arterial Stiffness and Long-Term Risk of Health Outcomes: The Framingham Heart Study. Hypertension. 2022 May; 79(5):1045-1056.View Related Profiles. PMID: 35168368; PMCID: PMC9009137; DOI: 10.1161/HYPERTENSIONAHA.121.18776;
     
  7. Lieb W, de Oliveira CM, Pan S, Echouffo-Tcheugui JB, Weber KS, Vasan RS, Xanthakis V. Clinical correlates of plasma insulin levels over the life course and association with incident type 2 diabetes: the Framingham Heart Study. BMJ Open Diabetes Res Care. 2022 02; 10(1). PMID: 35190401; PMCID: PMC8862500; DOI: 10.1136/bmjdrc-2021-002581;
     
  8. Vasan RS, Enserro DM, Beiser AS, Xanthakis V. Lifetime Risk of Heart Failure Among Participants in the Framingham Study. J Am Coll Cardiol. 2022 01 25; 79(3):250-263.View Related Profiles. PMID: 35057911; PMCID: PMC8820638; DOI: 10.1016/j.jacc.2021.10.043;
     
  9. Walker RL, Vlamakis H, Lee JWJ, Besse LA, Xanthakis V, Vasan RS, Shaw SY, Xavier RJ. Population study of the gut microbiome: associations with diet, lifestyle, and cardiometabolic disease. Genome Med. 2021 12 17; 13(1):188. PMID: 34915914; PMCID: PMC8680346; DOI: 10.1186/s13073-021-01007-5;
     
  10. Vasan RS, Song RJ, Xanthakis V, Beiser A, DeCarli C, Mitchell GF, Seshadri S. Hypertension-Mediated Organ Damage: Prevalence, Correlates, and Prognosis in the Community. Hypertension. 2022 03; 79(3):505-515.View Related Profiles. PMID: 35138872; PMCID: PMC8849561; DOI: 10.1161/HYPERTENSIONAHA.121.18502;
     
Showing 10 of 123 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 122 publications over 18 distinct years, with a maximum of 20 publications in 2020

YearPublications
19991
20022
20071
20081
20095
20108
20113
20128
20137
20146
20155
20166
20176
20187
20199
202020
202119
20228


AHA News: Overcoming Midlife Barriers to Exercise and Better Health

U.S. News & World Report 6/9/2021

AHA News: Overcoming Midlife Barriers to Exercise and Better Health

Drugs.com 6/9/2021

Healthy diet, exercise might be key to achieving optimal health in later years

HealthWorld 4/3/2021

Exercise, Healthy Diet in Midlife May Prevent Serious Health Conditions in Senior Years

Pharmacy Times 4/2/2021

Research shows how midlife diet, exercise can help in older adulthood

AJC 4/1/2021

Healthy Living in Middle Age Really Pays Off in Senior Years

HealthDay 3/31/2021

Study: Plant-Based Diets Improve Cardiac Function, Cognitive Health

Pharmacy Times 3/5/2021

Plant-based diet high in certain foods protects brain and heart

Slash Gear 3/5/2021

MIND diet, a combination of Mediterranean and DASH diets, associated with cardiac and cognitive benefits

Cardiovascular Business 2/26/2021

Research Suggests This Pair Of Superfood Families May Support Improved Heart & Brain Health

Mind Body Green 2/26/2021

Increased Blood Pressure During Exercise Could Predict Risk of CVD, Death

MD Magazine 5/20/2020

Ideal CV Health Over the Long Term Linked With Better Survival, Less Disease

tctMD 3/15/2020

The Longer You Follow a Healthier Lifestyle in Middle-Age The Lower Your Risk of Death Later in Life

Yahoo News 3/12/2020
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Biomarkers
Biostatistics
Epidemiology
Heart Failure
Multilevel modeling
Risk prediction
Screening
Ventricular remodeling

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