Vanessa Xanthakis, PhD
Assistant Professor
Boston University School of Medicine
Dept of Medicine
Preventive Medicine & Epidemiology

PhD, Boston University School of Public Health
MS, University of Athens

Dr. Vanessa Xanthakis is a biostatistician with training in applied mathematics and statistics, and has a strong commitment to clinical epidemiological research. Presently, she is an Assistant Professor in the Section of Preventive Medicine and Epidemiology in the Department of Medicine at Boston University School of Medicine and in the Biostatistics Department at Boston University School of Public Health. She is an investigator at the Framingham Heart Study and serves as the biostatistician on several investigations. She also serves as the Program Director for the Boston University T32 Program in Cardiovascular Epidemiology and the Promotion of Research In MEdical Residency (R38) program. She is the Director of Research Training for the Section of Preventive Medicine and Epidemiology. For the last 12 years, Dr. Xanthakis has focused her research on:

A) the epidemiology of cardiac remodeling and subclinical disease, including identifying cardiovascular disease risk factors;

B) population-based vascular testing and echocardiography, including identifying biological, environmental, and genetic determinants (correlates) of cardiac structure and function;

C) epidemiology of novel biomarkers including but not limited to natriuretic peptides, adipokines, and vascular growth factors;

D) cardiovascular risk prediction using biomarkers and assessing their incremental prognostic utility (focus of her PhD thesis);

E) epidemiology of heart failure and its precursors; and

F) ideal cardiovascular health and its impact on cardiovascular disease and its precursors.

Assistant Professor
Boston University School of Public Health

Framingham Heart Study

Boston University
Evans Center for Interdisciplinary Biomedical Research

Characterization of Functional Iron Deficiency and Repletion in Heart Failure with Preserved Ejection Fraction
08/15/2021 - 06/30/2025 (Subcontract PI)
The General Hospital Corporation d/b/a Massachusetts General Hospital NIH NHLBI

Racial/Ethnic Disparities in Heart Failure: A Cross-Cohort Collaboration
04/01/2021 - 03/31/2025 (Subcontract PI)
Kent County Memorial Hospital NIH NHLBI

Characterization of Molecular and Physiologic Signatures of Impaired Multi-Organ System Reserve Capacity During Exercise in Heart Failure with Preserved Ejection Fraction
04/01/2020 - 03/31/2024 (Subcontract PI)
Massachusetts General Hospital NIH NHLBI

Provider Agreement for Vanessa Xanthakis
12/14/2015 - 06/30/2016 (PI)
American Heart Association

Screening for Left Ventricular Dysfunction/Hypertrophy with Novel Biomarkers to Prevent Heart Failure
01/01/2013 - 12/31/2015 (PI)
American Heart Association

Plasma Nitrate: Clinical Correlates and Prognostic Significance
01/01/2012 - 12/31/2014 (PI)
University of Erlangen Nuremberg

Plasma Nitrate: Clinical Correlates and Prognostic Significance
01/01/2012 - 12/31/2012 (PI)
University of Erlangen Nuremberg


Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Bourdillon MT, Gaye B, Song RJ, Vasan RS, Xanthakis V. Notable paradoxical phenomena in associations between cardiovascular health score, subclinical and clinical cardiovascular disease in the community: The Framingham Heart Study. PLoS One. 2022; 17(5):e0267267.View Related Profiles. PMID: 35511823; PMCID: PMC9070900; DOI: 10.1371/journal.pone.0267267;
  2. Shrout TA, Pan S, Mitchell GF, Vasan RS, Xanthakis V. Association of orthostatic blood pressure response with incident heart failure: The Framingham Heart Study. PLoS One. 2022; 17(4):e0267057.View Related Profiles. PMID: 35452474; PMCID: PMC9032405; DOI: 10.1371/journal.pone.0267057;
  3. Vasan RS, Enserro DM, Xanthakis V, Beiser AS, Seshadri S. Temporal Trends in the Remaining Lifetime Risk of Cardiovascular Disease Among Middle-Aged Adults Across 6 Decades: The Framingham Study. Circulation. 2022 Apr 26; 145(17):1324-1338.View Related Profiles. PMID: 35430874; PMCID: PMC9038688; DOI: 10.1161/CIRCULATIONAHA.121.057889;
  4. Oelsner EC, Krishnaswamy A, Balte PP, Allen NB, Ali T, Anugu P, Andrews H, Arora K, Asaro A, Barr RG, Bertoni AG, Bon J, Boyle R, Chang AA, Chen G, Coady S, Cole SA, Coresh J, Cornell E, Correa A, Couper D, Cushman M, Demmer RT, Elkind MSV, Folsom AR, Fretts AM, Gabriel KP, Gallo L, Gutierrez J, Han MLK, Henderson JM, Howard VJ, Isasi CR, Jacobs DR, Judd SE, Mukaz DK, Kanaya AM, Kandula NR, Kaplan R, Kinney GL, Kucharska-Newton A, Lee JS, Lewis CE, Levine DA, Levitan EB, Levy B, Make B, Malloy K, Manly JJ, Mendoza-Puccini C, Meyer KA, Min YI, Moll M, Moore WC, Mauger D, Ortega VE, Palta P, Parker MM, Phipatanakul W, Post WS, Postow L, Psaty BM, Regan EA, Ring K, Roger VL, Rotter JI, Rundek T, Sacco RL, Schembri M, Schwartz DA, Seshadri S, Shikany JM, Sims M, Hinckley Stukovsky KD, Talavera GA, Tracy RP, Umans JG, Vasan RS, Watson K, Wenzel SE, Winters K, Woodruff PG, Xanthakis V, Zhang Y, Zhang Y, C R Investigators FT. Collaborative Cohort of Cohorts for COVID-19 Research (C4R) Study: Study Design. Am J Epidemiol. 2022 Mar 12.View Related Profiles. PMID: 35279711
  5. Bourdillon MT, Song RJ, Musa Yola I, Xanthakis V, Vasan RS. Prevalence, Predictors, Progression, and Prognosis of Hypertension Subtypes in the Framingham Heart Study. J Am Heart Assoc. 2022 03 15; 11(6):e024202.View Related Profiles. PMID: 35261291
  6. Vasan RS, Pan S, Xanthakis V, Beiser A, Larson MG, Seshadri S, Mitchell GF. Arterial Stiffness and Long-Term Risk of Health Outcomes: The Framingham Heart Study. Hypertension. 2022 May; 79(5):1045-1056.View Related Profiles. PMID: 35168368; PMCID: PMC9009137; DOI: 10.1161/HYPERTENSIONAHA.121.18776;
  7. Lieb W, de Oliveira CM, Pan S, Echouffo-Tcheugui JB, Weber KS, Vasan RS, Xanthakis V. Clinical correlates of plasma insulin levels over the life course and association with incident type 2 diabetes: the Framingham Heart Study. BMJ Open Diabetes Res Care. 2022 02; 10(1). PMID: 35190401; PMCID: PMC8862500; DOI: 10.1136/bmjdrc-2021-002581;
  8. Vasan RS, Enserro DM, Beiser AS, Xanthakis V. Lifetime Risk of Heart Failure Among Participants in the Framingham Study. J Am Coll Cardiol. 2022 01 25; 79(3):250-263.View Related Profiles. PMID: 35057911; PMCID: PMC8820638; DOI: 10.1016/j.jacc.2021.10.043;
  9. Walker RL, Vlamakis H, Lee JWJ, Besse LA, Xanthakis V, Vasan RS, Shaw SY, Xavier RJ. Population study of the gut microbiome: associations with diet, lifestyle, and cardiometabolic disease. Genome Med. 2021 12 17; 13(1):188. PMID: 34915914; PMCID: PMC8680346; DOI: 10.1186/s13073-021-01007-5;
  10. Vasan RS, Song RJ, Xanthakis V, Beiser A, DeCarli C, Mitchell GF, Seshadri S. Hypertension-Mediated Organ Damage: Prevalence, Correlates, and Prognosis in the Community. Hypertension. 2022 03; 79(3):505-515.View Related Profiles. PMID: 35138872; PMCID: PMC8849561; DOI: 10.1161/HYPERTENSIONAHA.121.18502;
Showing 10 of 123 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 122 publications over 18 distinct years, with a maximum of 20 publications in 2020

In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Heart Failure
Multilevel modeling
Risk prediction
Ventricular remodeling

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