Vasan Ramachandran | Profiles RNS

Vasan S. Ramachandran, MD

Professor

Boston University School of Medicine

Dept of Medicine

Preventive Medicine & Epidemiology

MD, All India Institute of Medical Science (AIIMS)
MBBS, All India Institute of Medical Science (AIIMS)
DM, All India Institute of Medical Science (AIIMS)

Websites

	Whitaker Cardiovascular Institute Training Program
	Vasan Ramachandran Named Coffman Professor in Vascular Medicine
	ResearchGate

ORCID : 0000-0001-7357-5970

Vasan S. Ramachandran, M.D., Principal Investigator and Director of the FHS, and Director of the FHS fellowship program in cardiovascular epidemiology for the last 25 years.

Dr. Ramachandran is a Professor of Medicine and Epidemiology at BUSM/BUSPH, and Chief, Section of Preventive Medicine and Epidemiology, Department of Medicine, BUSM. He is the Jay & Louis Coffman Professor of Vascular Medicine at BUSM. Dr. Ramachandran is a trained cardiologist with subspecialty training in echocardiography. He is a fellow of the AHA Councils on Epidemiology and Prevention and Functional Genomics and Translational Biology, and a fellow of the American College of Cardiology (ACC). He has extensive experience in supervising trainees at many levels and has taught the foundational core course on Cardiovascular Epidemiology at BUSPH (EP751). He has several active R01 grants from the NHLBI/NIDDK and received two K24 Mid-Career Investigator mentoring grants from the NHLBI. He has mentored several K23 awardees, and is currently the Principal Investigator of a post-doctoral training program (T32) in cardiovascular epidemiology. Overall, he has supervised over 70 trainees during the past 20 years; most are in key positions in academia. He received the Outstanding Mentor awards from the Department of Medicine, BUSM, and the AHA Council on Epidemiology and Prevention, and the prestigious AHA Population Science Award in 2014.

Importantly, Dr. Ramachandran’s own peer-reviewed funding spans thematic areas of genetics and genomics, cardiac and vascular remodeling, novel biomarkers, systems biology including proteomics and metabolomics, and stem cell biology. He has a 25-year history in research in cardiovascular epidemiology, including the two years he trained as a FHS fellow (1993-1995). He established the first School of Public Health in India between 1996-1998, serving as its inaugural director and the coordinator of its MPH program. He is the founding member and leader of the international EchoGen consortium, and chairs the Steering Committee of the Chronic Kidney Disease Biomarker Consortium funded by the NIDDK (U01DK085689). He is recognized internationally for translational research in cardiovascular epidemiology and lectures regularly at the AHA early career session on “how to develop a career in translational research and epidemiology/genetics.” He is well equipped to mentor trainees about grant writing having been a member of the Cardiovascular and Sleep (CASE) SRG, and an active reviewer of grants for national and international funding agencies. He served for many years on the NHLBI panel for reviewing K23-K24-K25 career development grants. He is well qualified to mentor trainees in best publication practices and has served until recently as an Associate Editor for Circulation, and the Editor-in-Chief of Circulation: Cardiovascular Genetics. He works directs the Center for Integrative Transdisciplinary Epidemiology within BUSM, that hosts multiple epidemiological datasets, including from multiple cohort studies, national surveys (NHANES), administrative databases and electronic health records; this center will be a valuable data source for trainees.

For the last 20 years, Dr. Ramachandran has focused his research on A) the genetic and non-genetic epidemiology of congestive heart failure, including identifying risk factors for the disease, characterizing the subgroups with diastolic heart failure, asymptomatic LV systolic and diastolic dysfunction, and evaluating the role of LV remodeling; B) population-based vascular testing and echocardiography, including identifying biological, environmental, and genetic determinants (correlates) of cardiac structure and function; normative standards; detailed assessment of biomarkers of the process of LV remodeling, including but not limited to role of natriuretic peptides, insulin resistance, cardiac extracellular matrix markers, oxidative stress, inflammation, growth factors; genetics of LV remodeling, LA and aortic structure and gene-environment interactions; brachial artery endothelial function, its correlates and tonometric assessment of large artery function; C) genetic and non-genetic epidemiology of high blood pressure, including characterizing the lifetime risk, rates of progression and risks associated with various degrees of elevation; large artery stiffness and function and role in systolic hypertension in the elderly; genetics of high blood pressure and large artery function; and D) CVD risk estimation in the short, medium- and long-term, with novel biomarkers including genomic biomarkers.

Jay & Louis Coffman Professor of Vascular Medicine
Boston University School of Medicine
Medicine

Professor
Boston University School of Public Health
Epidemiology

Section Chief
Boston University School of Medicine
Medicine
Preventive Medicine & Epidemiology

Principal Investigator & Director; Co-Director, Echocardiography/Vascular Laboratory
Framingham Heart Study

Member
Boston University
Whitaker Cardiovascular Institute

Member
Boston University
Evans Center for Interdisciplinary Biomedical Research

Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Graduate Medical Sciences

Founding Professor
Boston University
Computing & Data Sciences Administration

Director
Framingham Heart Study
Framingham Heart Study

BU Research
NIH RePORTER Research

RURAL: Risk Underlying Rural Areas Longitudinal Cohort Study
04/01/2019 - 04/30/2025 (PI)
NIH/National Heart, Lung, and Blood Institute
3U01HL146382-02S2

Whole-genome sequencing analysis of coronary atherosclerosis and related traits
03/17/2020 - 02/28/2025 (Subcontract PI)
University of Texas Health Science Center, Houston NIH NHLBI
1R01HL146860-01A1

PRIMER: Promoting Research In MEdical Residency
07/01/2020 - 06/30/2024 (PI)
NIH/National Heart, Lung, and Blood Institute
1R38HL143584-01A1

Plasma Proteome and Risk of Alzheimer Dementia and Related Endophenotypes in the Framingham Study
07/01/2019 - 03/31/2024 (Multi-PI)
PI: Vasan S. Ramachandran, MD
NIH/National Institute on Aging
1RF1AG063507-01

Return of Genomic Results and Estimating Penetrance in Population-Based Cohorts
08/01/2019 - 06/30/2023 (Subcontract PI)
Broad Institute, Inc., The NIH NHLBI
1R01HL143295-01A1

Plasma proteomics in CHS and population biology
07/15/2019 - 06/30/2023 (Subcontract PI)
University of Washington NIH NHLBI
5R01HL144483-02

Mediators of Systemic Inflammation and Heart Failure Risk in the Community
04/01/2019 - 03/31/2023 (Subcontract PI)
Cedars-Sinai Medical Center NIH NHLBI
5R01HL143227-02

Ventricular-vascular coupling in the elderly: lifecourse determinants, trajectories and prognostic significance
04/01/2019 - 02/28/2023 (PI)
NIH/National Heart, Lung, and Blood Institute
5R01HL142983-02

The Gut Microbiome and Bone Microarchitecture
08/06/2018 - 06/30/2022 (Subcontract PI)
Hebrew Rehabilitation Center For Aged, Inc. NIH NIAMS
2R01AR061445-06A1

Framingham Heart Study
04/01/2019 - 03/31/2021 (PI)
NIH/National Heart, Lung, and Blood Institute
75N92019D00031

Showing 10 of 53 results. Show All Results

Title

Yr	Title	Project-Sub Proj	Pubs
2021	RURAL: Risk Underlying Rural Areas Longitudinal Cohort Study	3U01HL146382-02S3
2021	Ventricular-vascular coupling in the elderly: lifecourse determinants, trajectories and prognostic significance	5R01HL142983-03	2
2020	Multidimensional Assessment of Brain Health as A Marker of Dementia Risk and Resilience	1R01AG066524-01A1
2020	RURAL: Risk Underlying Rural Areas Longitudinal Cohort Study	3U01HL146382-02S2
2020	RURAL: Risk Underlying Rural Areas Longitudinal Cohort Study	3U01HL146382-02S1
2020	PRIMER: Promoting Research In MEdical Residency	1R38HL143584-01A1
2020	RURAL: Risk Underlying Rural Areas Longitudinal Cohort Study	5U01HL146382-02
2020	Ventricular-vascular coupling in the elderly: lifecourse determinants, trajectories and prognostic significance	5R01HL142983-02	2
2020	Cardiometabolic Outcomes in Multi-ethnic Physical Activity & Sedentary Behavior Study (COMPASS)	5R01HL136266-05	11
2020	Multidisciplinary Training Program in Cardiovascular Epidemiology	5T32HL125232-05	26

Showing 10 of 95 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Tromp J, Paniagua SMA, Lau ES, Allen NB, Blaha MJ, Gansevoort RT, Hillege HL, Lee DE, Levy D, Ramachandran VS, van der Harst P, van Gilst WH, Larson MG, Shah SJ, de Boer RA, Lam CSP, Ho JE. Age dependent associations of risk factors with heart failure: pooled population based cohort study. BMJ. 2021 03 23; 372:n461.View Related Profiles.

Larson, Martin
Ramachandran, Vasan

PMID: 33758001

Surendran P, Feofanova EV, Lahrouchi N, Ntalla I, Karthikeyan S, Cook J, Chen L, Mifsud B, Yao C, Kraja AT, Cartwright JH, Hellwege JN, Giri A, Tragante V, Thorleifsson G, Liu DJ, Prins BP, Stewart ID, Cabrera CP, Eales JM, Akbarov A, Auer PL, Bielak LF, Bis JC, Braithwaite VS, Brody JA, Daw EW, Warren HR, Drenos F, Nielsen SF, Faul JD, Fauman EB, Fava C, Ferreira T, Foley CN, Franceschini N, Gao H, Giannakopoulou O, Giulianini F, Gudbjartsson DF, Guo X, Harris SE, Havulinna AS, Helgadottir A, Huffman JE, Hwang SJ, Kanoni S, Kontto J, Larson MG, Li-Gao R, Lindström J, Lotta LA, Lu Y, Luan J, Mahajan A, Malerba G, Masca NGD, Mei H, Menni C, Mook-Kanamori DO, Mosen-Ansorena D, Müller-Nurasyid M, Paré G, Paul DS, Perola M, Poveda A, Rauramaa R, Richard M, Richardson TG, Sepúlveda N, Sim X, Smith AV, Smith JA, Staley JR, Stanáková A, Sulem P, Thériault S, Thorsteinsdottir U, Trompet S, Varga TV, Velez Edwards DR, Veronesi G, Weiss S, Willems SM, Yao J, Young R, Yu B, Zhang W, Zhao JH, Zhao W, Zhao W, Evangelou E, Aeschbacher S, Asllanaj E, Blankenberg S, Bonnycastle LL, Bork-Jensen J, Brandslund I, Braund PS, Burgess S, Cho K, Christensen C, Connell J, Mutsert R, Dominiczak AF, Dörr M, Eiriksdottir G, Farmaki AE, Gaziano JM, Grarup N, Grove ML, Hallmans G, Hansen T, Have CT, Heiss G, Jørgensen ME, Jousilahti P, Kajantie E, Kamat M, Käräjämäki A, Karpe F, Koistinen HA, Kovesdy CP, Kuulasmaa K, Laatikainen T, Lannfelt L, Lee IT, Lee WJ, Linneberg A, Martin LW, Moitry M, Nadkarni G, Neville MJ, Palmer CNA, Papanicolaou GJ, Pedersen O, Peters J, Poulter N, Rasheed A, Rasmussen KL, Rayner NW, Mägi R, Renström F, Rettig R, Rossouw J, Schreiner PJ, Sever PS, Sigurdsson EL, Skaaby T, Sun YV, Sundstrom J, Thorgeirsson G, Esko T, Trabetti E, Tsao PS, Tuomi T, Turner ST, Tzoulaki I, Vaartjes I, Vergnaud AC, Willer CJ, Wilson PWF, Witte DR, Yonova-Doing E, Zhang H, Aliya N, Almgren P, Amouyel P, Asselbergs FW, Barnes MR, Blakemore AI, Boehnke M, Bots ML, Bottinger EP, Buring JE, Chambers JC, Chen YI, Chowdhury R, Conen D, Correa A, Davey Smith G, Boer RA, Deary IJ, Dedoussis G, Deloukas P, Di Angelantonio E, Elliott P, Felix SB, Ferrières J, Ford I, Fornage M, Franks PW, Franks S, Frossard P, Gambaro G, Gaunt TR, Groop L, Gudnason V, Harris TB, Hayward C, Hennig BJ, Herzig KH, Ingelsson E, Tuomilehto J, Järvelin MR, Jukema JW, Kardia SLR, Kee F, Kooner JS, Kooperberg C, Launer LJ, Lind L, Loos RJF, Majumder AAS, Laakso M, McCarthy MI, Melander O, Mohlke KL, Murray AD, Nordestgaard BG, Orho-Melander M, Packard CJ, Padmanabhan S, Palmas W, Polasek O, Porteous DJ, Prentice AM, Province MA, Relton CL, Rice K, Ridker PM, Rolandsson O, Rosendaal FR, Rotter JI, Rudan I, Salomaa V, Samani NJ, Sattar N, Sheu WH, Smith BH, Soranzo N, Spector TD, Starr JM, Sebert S, Taylor KD, Lakka TA, Timpson NJ, Tobin MD, van der Harst P, van der Meer P, Ramachandran VS, Verweij N, Virtamo J, Völker U, Weir DR, Zeggini E, Charchar FJ, Wareham NJ, Langenberg C, Tomaszewski M, Butterworth AS, Caulfield MJ, Danesh J, Edwards TL, Holm H, Hung AM, Lindgren CM, Liu C, Manning AK, Morris AP, Morrison AC, O'Donnell CJ, Psaty BM, Saleheen D, Stefansson K, Boerwinkle E, Chasman DI, Levy D, Newton-Cheh C, Munroe PB, Howson JMM. Publisher Correction: Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals. Nat Genet. 2021 Mar 16.View Related Profiles.

O'Donnell, Christopher
Gaziano, J. Michael
Buring, Julie
Larson, Martin
Hwang, Shih-Jen
Ramachandran, Vasan

PMID: 33727701

Lin BM, Grinde KE, Brody JA, Breeze CE, Raffield LM, Mychaleckyj JC, Thornton TA, Perry JA, Baier LJ, de Las Fuentes L, Guo X, Heavner BD, Hanson RL, Hung YJ, Qian H, Hsiung CA, Hwang SJ, Irvin MR, Jain D, Kelly TN, Kobes S, Lange L, Lash JP, Li Y, Liu X, Mi X, Musani SK, Papanicolaou GJ, Parsa A, Reiner AP, Salimi S, Sheu WH, Shuldiner AR, Taylor KD, Smith AV, Smith JA, Tin A, Vaidya D, Wallace RB, Yamamoto K, Sakaue S, Matsuda K, Kamatani Y, Momozawa Y, Yanek LR, Young BA, Zhao W, Okada Y, Abecasis G, Psaty BM, Arnett DK, Boerwinkle E, Cai J, Yii-Der Chen I, Correa A, Cupples LA, He J, Kardia SL, Kooperberg C, Mathias RA, Mitchell BD, Nickerson DA, Turner ST, Vasan RS, Rotter JI, Levy D, Kramer HJ, Köttgen A, Nhlbi Trans-Omics For Precision Medicine TOPMed Consortium, TOPMed Kidney Working Group, Rich SS, Lin DY, Browning SR, Franceschini N. Whole genome sequence analyses of eGFR in 23,732 people representing multiple ancestries in the NHLBI trans-omics for precision medicine (TOPMed) consortium. EBioMedicine. 2021 Jan; 63:103157.View Related Profiles.

Cupples, L
Hwang, Shih-Jen
Ramachandran, Vasan

PMID: 33418499

Vasan RS, Zachariah JP, Xanthakis V. Life Course Developmental Approach to Cardiovascular Health and Cardiovascular Disease Prevention: Opportunities and Unanswered Questions. J Am Coll Cardiol. 2020 12 08; 76(23):2708-2711.View Related Profiles.

Xanthakis, Vanessa
Ramachandran, Vasan

PMID: 33272364

Surendran P, Feofanova EV, Lahrouchi N, Ntalla I, Karthikeyan S, Cook J, Chen L, Mifsud B, Yao C, Kraja AT, Cartwright JH, Hellwege JN, Giri A, Tragante V, Thorleifsson G, Liu DJ, Prins BP, Stewart ID, Cabrera CP, Eales JM, Akbarov A, Auer PL, Bielak LF, Bis JC, Braithwaite VS, Brody JA, Daw EW, Warren HR, Drenos F, Nielsen SF, Faul JD, Fauman EB, Fava C, Ferreira T, Foley CN, Franceschini N, Gao H, Giannakopoulou O, Giulianini F, Gudbjartsson DF, Guo X, Harris SE, Havulinna AS, Helgadottir A, Huffman JE, Hwang SJ, Kanoni S, Kontto J, Larson MG, Li-Gao R, Lindström J, Lotta LA, Lu Y, Luan J, Mahajan A, Malerba G, Masca NGD, Mei H, Menni C, Mook-Kanamori DO, Mosen-Ansorena D, Müller-Nurasyid M, Paré G, Paul DS, Perola M, Poveda A, Rauramaa R, Richard M, Richardson TG, Sepúlveda N, Sim X, Smith AV, Smith JA, Staley JR, Stanáková A, Sulem P, Thériault S, Thorsteinsdottir U, Trompet S, Varga TV, Velez Edwards DR, Veronesi G, Weiss S, Willems SM, Yao J, Young R, Yu B, Zhang W, Zhao JH, Zhao W, Zhao W, Evangelou E, Aeschbacher S, Asllanaj E, Blankenberg S, Bonnycastle LL, Bork-Jensen J, Brandslund I, Braund PS, Burgess S, Cho K, Christensen C, Connell J, Mutsert R, Dominiczak AF, Dörr M, Eiriksdottir G, Farmaki AE, Gaziano JM, Grarup N, Grove ML, Hallmans G, Hansen T, Have CT, Heiss G, Jørgensen ME, Jousilahti P, Kajantie E, Kamat M, Käräjämäki A, Karpe F, Koistinen HA, Kovesdy CP, Kuulasmaa K, Laatikainen T, Lannfelt L, Lee IT, Lee WJ, Linneberg A, Martin LW, Moitry M, Nadkarni G, Neville MJ, Palmer CNA, Papanicolaou GJ, Pedersen O, Peters J, Poulter N, Rasheed A, Rasmussen KL, Rayner NW, Mägi R, Renström F, Rettig R, Rossouw J, Schreiner PJ, Sever PS, Sigurdsson EL, Skaaby T, Sun YV, Sundstrom J, Thorgeirsson G, Esko T, Trabetti E, Tsao PS, Tuomi T, Turner ST, Tzoulaki I, Vaartjes I, Vergnaud AC, Willer CJ, Wilson PWF, Witte DR, Yonova-Doing E, Zhang H, Aliya N, Almgren P, Amouyel P, Asselbergs FW, Barnes MR, Blakemore AI, Boehnke M, Bots ML, Bottinger EP, Buring JE, Chambers JC, Chen YI, Chowdhury R, Conen D, Correa A, Davey Smith G, Boer RA, Deary IJ, Dedoussis G, Deloukas P, Di Angelantonio E, Elliott P, Felix SB, Ferrières J, Ford I, Fornage M, Franks PW, Franks S, Frossard P, Gambaro G, Gaunt TR, Groop L, Gudnason V, Harris TB, Hayward C, Hennig BJ, Herzig KH, Ingelsson E, Tuomilehto J, Järvelin MR, Jukema JW, Kardia SLR, Kee F, Kooner JS, Kooperberg C, Launer LJ, Lind L, Loos RJF, Majumder AAS, Laakso M, McCarthy MI, Melander O, Mohlke KL, Murray AD, Nordestgaard BG, Orho-Melander M, Packard CJ, Padmanabhan S, Palmas W, Polasek O, Porteous DJ, Prentice AM, Province MA, Relton CL, Rice K, Ridker PM, Rolandsson O, Rosendaal FR, Rotter JI, Rudan I, Salomaa V, Samani NJ, Sattar N, Sheu WH, Smith BH, Soranzo N, Spector TD, Starr JM, Sebert S, Taylor KD, Lakka TA, Timpson NJ, Tobin MD, van der Harst P, van der Meer P, Ramachandran VS, Verweij N, Virtamo J, Völker U, Weir DR, Zeggini E, Charchar FJ, Wareham NJ, Langenberg C, Tomaszewski M, Butterworth AS, Caulfield MJ, Danesh J, Edwards TL, Holm H, Hung AM, Lindgren CM, Liu C, Manning AK, Morris AP, Morrison AC, O'Donnell CJ, Psaty BM, Saleheen D, Stefansson K, Boerwinkle E, Chasman DI, Levy D, Newton-Cheh C, Munroe PB, Howson JMM. Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals. Nat Genet. 2020 12; 52(12):1314-1332.View Related Profiles.

O'Donnell, Christopher
Gaziano, J. Michael
Buring, Julie
Larson, Martin
Hwang, Shih-Jen
Ramachandran, Vasan

PMID: 33230300

Sanders JL, Putman RK, Dupuis J, Xu H, Murabito JM, Araki T, Nishino M, Benjamin EJ, Levy DL, Vasan RS, Washko GR, Curtis JL, Freeman CM, Bowler R, Hatabu H, O'Connor GT, Hunninghake GM. The Association of Aging Biomarkers, Interstitial Lung Abnormalities, and Mortality. Am J Respir Crit Care Med. 2020 Oct 20.View Related Profiles.

Benjamin, Emelia
O'Connor, George
Murabito, Joanne
Dupuis, Josee
Ramachandran, Vasan

PMID: 33080140

Khera R, Pandey A, Ayers CR, Carnethon MR, Greenland P, Ndumele CE, Nambi V, Seliger SL, Chaves PHM, Safford MM, Cushman M, Xanthakis V, Vasan RS, Mentz RJ, Correa A, Lloyd-Jones DM, Berry JD, de Lemos JA, Neeland IJ. Performance of the Pooled Cohort Equations to Estimate Atherosclerotic Cardiovascular Disease Risk by Body Mass Index. JAMA Netw Open. 2020 10 01; 3(10):e2023242.View Related Profiles.

Xanthakis, Vanessa
Ramachandran, Vasan

PMID: 33119108

Cooper LL, Musani SK, Moore JA, Clarke VA, Yano Y, Cobbs K, Tsao CW, Butler J, Hall ME, Hamburg NM, Benjamin EJ, Vasan RS, Mitchell GF, Fox ER. Clinical Associations of Vascular Stiffness, Microvascular Dysfunction, and Prevalent Cardiovascular Disease in a Black Cohort: The Jackson Heart Study. J Am Heart Assoc. 2020 09 15; 9(18):e017018.View Related Profiles.

Benjamin, Emelia
Hamburg, Naomi
Ramachandran, Vasan

PMID: 32873113

Greenberg JH, Abraham AG, Xu Y, Schelling JR, Feldman HI, Sabbisetti VS, Gonzalez MC, Coca S, Schrauben SJ, Waikar SS, Ramachandran VS, Shlipak MG, Warady B, Kimmel PL, Bonventre JV, Denburg M, Parikh CR, Furth S. Plasma Biomarkers of Tubular Injury and Inflammation Are Associated with CKD Progression in Children. J Am Soc Nephrol. 2020 05; 31(5):1067-1077.View Related Profiles.

Waikar, Sushrut
Ramachandran, Vasan

PMID: 32234829

So-Armah KA, Lim JK, Lo Re V, Tate JP, Chang CH, Butt AA, Gibert CL, Rimland D, Marconi VC, Goetz MB, Ramachandran V, Brittain E, Long M, Nguyen KL, Rodriguez-Barradas MC, Budoff MJ, Tindle HA, Samet JH, Justice AC, Freiberg MS. FIB-4 stage of liver fibrosis is associated with incident heart failure with preserved, but not reduced, ejection fraction among people with and without HIV or hepatitis C. Prog Cardiovasc Dis. 2020 Mar - Apr; 63(2):184-191.View Related Profiles.

Samet, Jeffrey
So-Armah, Kaku
Long, Michelle
Ramachandran, Vasan

PMID: 32068085

Showing 10 of 799 results. Show More

Xu J, Gaddis NC, Bartz TM, Hou R, Manichaikul AW, Pankratz N, Smith AV, Sun F, Terzikhan N, Markunas CA, Patchen BK, Schu M, Beydoun MA, Brusselle GG, Eiriksdottir G, Zhou X, Wood AC, Graff M, Harris TB, Ikram MA, Jacobs DR, Launer LJ, Lemaitre RN, O'Connor GT, Oelsner EC, Psaty BM, Vasan RS, Rohde RR, Rich SS, Rotter JI, Seshadri S, Smith LJ, Tiemeier H, Tsai MY, Uitterlinden AG, Voruganti VS, Xu H, Zilhão NR, Fornage M, Zillikens MC, London SJ, Barr RG, Dupuis J, Gharib SA, Gudnason V, Lahousse L, North KE, Steffen LM, Cassano PA, Hancock DB. Omega-3 Fatty Acids and Genome-Wide Interaction Analyses Reveal DPP10-Pulmonary Function Association. Am J Respir Crit Care Med. 2019 03 01; 199(5):631-642.View Related Profiles.

O'Connor, George
Dupuis, Josee
Seshadri, Sudha
Ramachandran, Vasan

PMID: 30199657

Harris WS, Tintle NL, Ramachandran VS. Erythrocyte n-6 Fatty Acids and Risk for Cardiovascular Outcomes and Total Mortality in the Framingham Heart Study. Nutrients. 2018 Dec 19; 10(12). PMID: 30572606

Zekavat SM, Ruotsalainen S, Handsaker RE, Alver M, Bloom J, Poterba T, Seed C, Ernst J, Chaffin M, Engreitz J, Peloso GM, Manichaikul A, Yang C, Ryan KA, Fu M, Johnson WC, Tsai M, Budoff M, Vasan RS, Cupples LA, Rotter JI, Rich SS, Post W, Mitchell BD, Correa A, Metspalu A, Wilson JG, Salomaa V, Kellis M, Daly MJ, Neale BM, McCarroll S, Surakka I, Esko T, Ganna A, Ripatti S, Kathiresan S, Natarajan P. Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries. Nat Commun. 2018 07 04; 9(1):2606.View Related Profiles.

Peloso, Gina
Cupples, L
Ramachandran, Vasan

PMID: 29973585

de Boer RA, Nayor M, deFilippi CR, Enserro D, Bhambhani V, Kizer JR, Blaha MJ, Brouwers FP, Cushman M, Lima JAC, Bahrami H, van der Harst P, Wang TJ, Gansevoort RT, Fox CS, Gaggin HK, Kop WJ, Liu K, Vasan RS, Psaty BM, Lee DS, Hillege HL, Bartz TM, Benjamin EJ, Chan C, Allison M, Gardin JM, Januzzi JL, Shah SJ, Levy D, Herrington DM, Larson MG, van Gilst WH, Gottdiener JS, Bertoni AG, Ho JE. Association of Cardiovascular Biomarkers With Incident Heart Failure With Preserved and Reduced Ejection Fraction. JAMA Cardiol. 2018 03 01; 3(3):215-224.View Related Profiles.

Benjamin, Emelia
Larson, Martin
Nayor, Matthew
Ramachandran, Vasan

PMID: 29322198

Nayor M, Duncan MS, Musani SK, Xanthakis V, LaValley MP, Larson MG, Fox ER, Vasan RS. Incidence of cardiovascular disease in individuals affected by recent changes to US blood pressure treatment guidelines. J Hypertens. 2018 02; 36(2):436-443.View Related Profiles.

Larson, Martin
Nayor, Matthew
LaValley, Michael
Xanthakis, Vanessa
Ramachandran, Vasan

PMID: 29084083

Jørgensen ME, Andersson C, Vasan RS, Køber L, Abdulla J. Characteristics and prognosis of heart failure with improved compared with persistently reduced ejection fraction: A systematic review and meta-analyses. Eur J Prev Cardiol. 2018 03; 25(4):366-376. PMID: 29313369; DOI: 10.1177/2047487317750437;

Weinstein G, Zelber-Sagi S, Preis SR, Beiser AS, DeCarli C, Speliotes EK, Satizabal CL, Vasan RS, Seshadri S. Association of Nonalcoholic Fatty Liver Disease With Lower Brain Volume in Healthy Middle-aged Adults in the Framingham Study. JAMA Neurol. 2018 01 01; 75(1):97-104.View Related Profiles.

Beiser, Alexa
Satizabal, Claudia
Weinstein, Galit
Preis, Sarah
Seshadri, Sudha
Ramachandran, Vasan

PMID: 29159396

Sarnowski C, Satizabal CL, DeCarli C, Pitsillides AN, Cupples LA, Vasan RS, Wilson JG, Bis JC, Fornage M, Beiser AS, DeStefano AL, Dupuis J, Seshadri S. Whole genome sequence analyses of brain imaging measures in the Framingham Study. Neurology. 2018 01 16; 90(3):e188-e196.View Related Profiles.

Beiser, Alexa
DeStefano, Anita
Sarnowski, Chloe
Satizabal, Claudia
Dupuis, Josee
Cupples, L
Yang, Qiong
Seshadri, Sudha
Ramachandran, Vasan

PMID: 29282330

Zachariah JP, Rong J, Larson MG, Hamburg NM, Benjamin EJ, Vasan RS, Mitchell GF. Metabolic Predictors of Change in Vascular Function: Prospective Associations From a Community-Based Cohort. Hypertension. 2018 02; 71(2):237-242.View Related Profiles.

Benjamin, Emelia
Larson, Martin
Hamburg, Naomi
Ramachandran, Vasan

PMID: 29279312

Benson MD, Yang Q, Ngo D, Zhu Y, Shen D, Farrell LA, Sinha S, Keyes MJ, Vasan RS, Larson MG, Smith JG, Wang TJ, Gerszten RE. Genetic Architecture of the Cardiovascular Risk Proteome. Circulation. 2018 03 13; 137(11):1158-1172.View Related Profiles.

Larson, Martin
Yang, Qiong
Ramachandran, Vasan

PMID: 29258991

Bhambhani V, Kizer JR, Lima JAC, van der Harst P, Bahrami H, Nayor M, de Filippi CR, Enserro D, Blaha MJ, Cushman M, Wang TJ, Gansevoort RT, Fox CS, Gaggin HK, Kop WJ, Liu K, Vasan RS, Psaty BM, Lee DS, Brouwers FP, Hillege HL, Bartz TM, Benjamin EJ, Chan C, Allison M, Gardin JM, Januzzi JL, Levy D, Herrington DM, van Gilst WH, Bertoni AG, Larson MG, de Boer RA, Gottdiener JS, Shah SJ, Ho JE. Predictors and outcomes of heart failure with mid-range ejection fraction. Eur J Heart Fail. 2018 04; 20(4):651-659.View Related Profiles.

Benjamin, Emelia
Larson, Martin
Nayor, Matthew
Ramachandran, Vasan

PMID: 29226491

Ko D, Preis SR, Lubitz SA, McManus DD, Vasan RS, Hamburg NM, Benjamin EJ, Mitchell GF. Relation of Orthostatic Hypotension With New-Onset Atrial Fibrillation (From the Framingham Heart Study). Am J Cardiol. 2018 03 01; 121(5):596-601.View Related Profiles.

Ko, Darae
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PMID: 29290367

Adams S, Conner S, Himali JJ, Beiser A, Vasan RS, Seshadri S, Pase MP. Vascular risk factor burden and new-onset depression in the community. Prev Med. 2018 06; 111:348-350.View Related Profiles.

Beiser, Alexa
Himali, Jayandra
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PMID: 29197532; DOI: 10.1016/j.ypmed.2017.11.022;

Maas R, Xanthakis V, Göen T, Müller J, Schwedhelm E, Böger RH, Vasan RS. Plasma Nitrate and Incidence of Cardiovascular Disease and All-Cause Mortality in the Community: The Framingham Offspring Study. J Am Heart Assoc. 2017 11 18; 6(11).View Related Profiles.

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Ramachandran, Vasan

PMID: 29151027

Staerk L, Wang B, Lunetta KL, Helm RH, Ko D, Sherer JA, Ellinor PT, Lubitz SA, McManus DD, Vasan RS, Benjamin EJ, Trinquart L. Association Between Leukocyte Telomere Length and the Risk of Incident Atrial Fibrillation: The Framingham Heart Study. J Am Heart Assoc. 2017 Nov 14; 6(11).View Related Profiles.

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PMID: 29138179

McGrath ER, Beiser AS, DeCarli C, Plourde KL, Vasan RS, Greenberg SM, Seshadri S. Blood pressure from mid- to late life and risk of incident dementia. Neurology. 2017 Dec 12; 89(24):2447-2454.View Related Profiles.

Beiser, Alexa
Seshadri, Sudha
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PMID: 29117954

Shah RV, Yeri AS, Murthy VL, Massaro JM, D'Agostino R, Freedman JE, Long MT, Fox CS, Das S, Benjamin EJ, Vasan RS, O'Donnell CJ, Hoffmann U. Association of Multiorgan Computed Tomographic Phenomap With Adverse Cardiovascular Health Outcomes: The Framingham Heart Study. JAMA Cardiol. 2017 11 01; 2(11):1236-1246.View Related Profiles.

O'Donnell, Christopher
Benjamin, Emelia
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PMID: 28975197

O'Sullivan JF, Morningstar JE, Yang Q, Zheng B, Gao Y, Jeanfavre S, Scott J, Fernandez C, Zheng H, O'Connor S, Cohen P, Vasan RS, Long MT, Wilson JG, Melander O, Wang TJ, Fox C, Peterson RT, Clish CB, Corey KE, Gerszten RE. Dimethylguanidino valeric acid is a marker of liver fat and predicts diabetes. J Clin Invest. 2017 12 01; 127(12):4394-4402.View Related Profiles.

Long, Michelle
Yang, Qiong
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PMID: 29083323

Brody JA, Morrison AC, Bis JC, O'Connell JR, Brown MR, Huffman JE, Ames DC, Carroll A, Conomos MP, Gabriel S, Gibbs RA, Gogarten SM, Gupta N, Jaquish CE, Johnson AD, Lewis JP, Liu X, Manning AK, Papanicolaou GJ, Pitsillides AN, Rice KM, Salerno W, Sitlani CM, Smith NL, Heckbert SR, Laurie CC, Mitchell BD, Vasan RS, Rich SS, Rotter JI, Wilson JG, Boerwinkle E, Psaty BM, Cupples LA. Analysis commons, a team approach to discovery in a big-data environment for genetic epidemiology. Nat Genet. 2017 10 27; 49(11):1560-1563.View Related Profiles.

Cupples, L
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PMID: 29074945

Zakharov MN, Bhasin S, Travison TG, Xue R, Ulloor J, Ramachandran V, Carter E, Wu F, Jasuja R. Corrigendum to "A multi-step, allosteric model of testosterone's binding to sex hormone binding globulin" [Mol. Cell. Endocrinol. 399 (2015) 190-200]. Mol Cell Endocrinol. 2017 10 15; 454:167.View Related Profiles.

Ulloor, Jagadish
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PMID: 28780939

Andersson C, Vasan RS. Epidemiology of cardiovascular disease in young individuals. Nat Rev Cardiol. 2018 04; 15(4):230-240. PMID: 29022571; DOI: 10.1038/nrcardio.2017.154;

Fetterman JL, Liu C, Mitchell GF, Vasan RS, Benjamin EJ, Vita JA, Hamburg NM, Levy D. Relations of mitochondrial genetic variants to measures of vascular function. Mitochondrion. 2018 05; 40:51-57.View Related Profiles.

Liu, Chunyu
Levy, Daniel
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PMID: 28993255

Vasan RS, Xanthakis V, Lyass A, Andersson C, Tsao C, Cheng S, Aragam J, Benjamin EJ, Larson MG. Epidemiology of Left Ventricular Systolic Dysfunction and Heart Failure in the Framingham Study: An Echocardiographic Study Over 3 Decades. JACC Cardiovasc Imaging. 2018 01; 11(1):1-11.View Related Profiles.

Benjamin, Emelia
Aragam, Jayashri
Larson, Martin
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Ramachandran, Vasan

PMID: 28917679

Delling FN, Li X, Li S, Yang Q, Xanthakis V, Martinsson A, Andell P, Lehman BT, Osypiuk EW, Stantchev P, Zöller B, Benjamin EJ, Sundquist K, Vasan RS, Smith JG. Heritability of Mitral Regurgitation: Observations From the Framingham Heart Study and Swedish Population. Circ Cardiovasc Genet. 2017 Oct; 10(5).View Related Profiles.

Benjamin, Emelia
Osypiuk, Ewa
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PMID: 28993406

Niiranen TJ, Larson MG, McCabe EL, Xanthakis V, Vasan RS, Cheng S. Prognosis of Prehypertension Without Progression to Hypertension. Circulation. 2017 09 26; 136(13):1262-1264.View Related Profiles.

Larson, Martin
Xanthakis, Vanessa
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PMID: 28947482

Cooper LL, Himali JJ, Torjesen A, Tsao CW, Beiser A, Hamburg NM, DeCarli C, Vasan RS, Seshadri S, Pase MP, Mitchell GF. Inter-Relations of Orthostatic Blood Pressure Change, Aortic Stiffness, and Brain Structure and Function in Young Adults. J Am Heart Assoc. 2017 Aug 17; 6(8).View Related Profiles.

Beiser, Alexa
Himali, Jayandra
Hamburg, Naomi
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Ramachandran, Vasan

PMID: 28862943; DOI: 10.1161/JAHA.117.006206;

Kent ST, Rosenson RS, Avery CL, Chen YI, Correa A, Cummings SR, Cupples LA, Cushman M, Evans DS, Gudnason V, Harris TB, Howard G, Irvin MR, Judd SE, Jukema JW, Lange L, Levitan EB, Li X, Liu Y, Post WS, Postmus I, Psaty BM, Rotter JI, Safford MM, Sitlani CM, Smith AV, Stewart JD, Trompet S, Sun F, Vasan RS, Woolley JM, Whitsel EA, Wiggins KL, Wilson JG, Muntner P. PCSK9 Loss-of-Function Variants, Low-Density Lipoprotein Cholesterol, and Risk of Coronary Heart Disease and Stroke: Data From 9 Studies of Blacks and Whites. Circ Cardiovasc Genet. 2017 Aug; 10(4):e001632.View Related Profiles.

Cupples, L
Ramachandran, Vasan

PMID: 28768753

Niiranen TJ, McCabe EL, Larson MG, Henglin M, Lakdawala NK, Vasan RS, Cheng S. Risk for hypertension crosses generations in the community: a multi-generational cohort study. Eur Heart J. 2017 Aug 01; 38(29):2300-2308.View Related Profiles.

Larson, Martin
Lakdawala, Neal
Ramachandran, Vasan

PMID: 28430902; DOI: 10.1093/eurheartj/ehx134;

Jasuja GK, Travison TG, Murabito JM, Davda MN, Rose AJ, Basaria S, Coviello A, Vasan RS, D'Agostino R, Bhasin S. Circulating Estrogen Levels and Self-Reported Health and Mobility Limitation in Community-Dwelling Men of the Framingham Heart Study. J Gerontol A Biol Sci Med Sci. 2017 Aug 01; 72(8):1137-1142.View Related Profiles.

Rose, Adam
Jasuja, Guneet
Murabito, Joanne
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Bhasin, Shalender
Ramachandran, Vasan

PMID: 28329787; DOI: 10.1093/gerona/glw197;

Li W, Dorans KS, Wilker EH, Rice MB, Ljungman PL, Schwartz JD, Coull BA, Koutrakis P, Gold DR, Keaney JF, Vasan RS, Benjamin EJ, Mittleman MA. Short-Term Exposure to Ambient Air Pollution and Biomarkers of Systemic Inflammation: The Framingham Heart Study. Arterioscler Thromb Vasc Biol. 2017 Sep; 37(9):1793-1800.View Related Profiles.

Benjamin, Emelia
Ramachandran, Vasan

PMID: 28751572

Sardana M, Nah G, Tsao CW, Ogunsua AA, Vittinghoff E, Thomas RC, Cheng S, Vaze A, Aragam JR, Mitchell GF, Benjamin EJ, Vasan RS, Aurigemma GP, Schiller NB, McManus DD, Parikh NI. Clinical and Echocardiographic Correlates of Left Atrial Function Index: The Framingham Offspring Study. J Am Soc Echocardiogr. 2017 Sep; 30(9):904-912.e2.View Related Profiles.

Benjamin, Emelia
Aragam, Jayashri
Ramachandran, Vasan

PMID: 28735892

Seyerle AA, Sitlani CM, Noordam R, Gogarten SM, Li J, Li X, Evans DS, Sun F, Laaksonen MA, Isaacs A, Kristiansson K, Highland HM, Stewart JD, Harris TB, Trompet S, Bis JC, Peloso GM, Brody JA, Broer L, Busch EL, Duan Q, Stilp AM, O'Donnell CJ, Macfarlane PW, Floyd JS, Kors JA, Lin HJ, Li-Gao R, Sofer T, Méndez-Giráldez R, Cummings SR, Heckbert SR, Hofman A, Ford I, Li Y, Launer LJ, Porthan K, Newton-Cheh C, Napier MD, Kerr KF, Reiner AP, Rice KM, Roach J, Buckley BM, Soliman EZ, de Mutsert R, Sotoodehnia N, Uitterlinden AG, North KE, Lee CR, Gudnason V, Stürmer T, Rosendaal FR, Taylor KD, Wiggins KL, Wilson JG, Chen YD, Kaplan RC, Wilhelmsen K, Cupples LA, Salomaa V, van Duijn C, Jukema JW, Liu Y, Mook-Kanamori DO, Lange LA, Vasan RS, Smith AV, Stricker BH, Laurie CC, Rotter JI, Whitsel EA, Psaty BM, Avery CL. Pharmacogenomics study of thiazide diuretics and QT interval in multi-ethnic populations: the cohorts for heart and aging research in genomic epidemiology. Pharmacogenomics J. 2018 04; 18(2):215-226.View Related Profiles.

O'Donnell, Christopher
Peloso, Gina
Cupples, L
Ramachandran, Vasan

PMID: 28719597

Zachariah JP, Quiroz R, Nelson KP, Teng Z, Keaney JF, Sullivan LM, Vasan RS. Prospective Relation of Circulating Adipokines to Incident Metabolic Syndrome: The Framingham Heart Study. J Am Heart Assoc. 2017 Jul 16; 6(7).View Related Profiles.

Nelson, Kerrie
Sullivan, Lisa
Ramachandran, Vasan

PMID: 28713076

Zachariah JP, Quiroz R, Enserro D, Andersson C, Keaney JF, Sullivan LM, Vasan RS. Association of Parental Obesity and Diabetes Mellitus With Circulating Adipokines in Nonobese Nondiabetic Offspring. J Am Heart Assoc. 2017 Jul 16; 6(7).View Related Profiles.

Sullivan, Lisa
Ramachandran, Vasan

PMID: 28713075

Wheelock KM, Cai J, Looker HC, Merchant ML, Nelson RG, Fufaa GD, Weil EJ, Feldman HI, Vasan RS, Kimmel PL, Rovin BH, Mauer M, Klein JB. Plasma bradykinin and early diabetic nephropathy lesions in type 1 diabetes mellitus. PLoS One. 2017; 12(7):e0180964. PMID: 28700653; DOI: 10.1371/journal.pone.0180964;

Aparicio HJ, Himali JJ, Beiser AS, Davis-Plourde KL, Vasan RS, Kase CS, Wolf PA, Seshadri S. Overweight, Obesity, and Survival After Stroke in the Framingham Heart Study. J Am Heart Assoc. 2017 Jun 24; 6(6).View Related Profiles.

Beiser, Alexa
Kase, Carlos
Aparicio, Hugo
Himali, Jayandra
Wolf, Philip
Seshadri, Sudha
Ramachandran, Vasan

PMID: 28647687

Rebholz CM, Inker LA, Chen Y, Liang M, Foster MC, Eckfeldt JH, Kimmel PL, Vasan RS, Feldman HI, Sarnak MJ, Hsu CY, Levey AS, Coresh J. Risk of ESRD and Mortality Associated With Change in Filtration Markers. Am J Kidney Dis. 2017 Oct; 70(4):551-560. PMID: 28648303; DOI: 10.1053/j.ajkd.2017.04.025;

Aparicio HJ, Petrea RE, Massaro JM, Manning WJ, Oyama-Manabe N, Beiser AS, Kase CS, D'Agostino RB, Wolf PA, Vasan RS, DeCarli C, O'Donnell CJ, Seshadri S. Association of descending thoracic aortic plaque with brain atrophy and white matter hyperintensities: The Framingham Heart Study. Atherosclerosis. 2017 Oct; 265:305-311.View Related Profiles.

Beiser, Alexa
Kase, Carlos
O'Donnell, Christopher
Aparicio, Hugo
Massaro, Joseph
Wolf, Philip
D'Agostino, Ralph
Seshadri, Sudha
Ramachandran, Vasan

PMID: 28673480

Chouraki V, Preis SR, Yang Q, Beiser A, Li S, Larson MG, Weinstein G, Wang TJ, Gerszten RE, Vasan RS, Seshadri S. Association of amine biomarkers with incident dementia and Alzheimer's disease in the Framingham Study. Alzheimers Dement. 2017 Dec; 13(12):1327-1336.View Related Profiles.

Beiser, Alexa
Weinstein, Galit
Larson, Martin
Yang, Qiong
Preis, Sarah
Seshadri, Sudha
Ramachandran, Vasan

PMID: 28602601

Saber H, Himali JJ, Beiser AS, Shoamanesh A, Pikula A, Roubenoff R, Romero JR, Kase CS, Vasan RS, Seshadri S. Serum Insulin-Like Growth Factor 1 and the Risk of Ischemic Stroke: The Framingham Study. Stroke. 2017 Jul; 48(7):1760-1765.View Related Profiles.

Beiser, Alexa
Kase, Carlos
Himali, Jayandra
Romero, Jose
Seshadri, Sudha
Ramachandran, Vasan

PMID: 28596451

Tan ZS, Spartano NL, Beiser AS, DeCarli C, Auerbach SH, Vasan RS, Seshadri S. Physical Activity, Brain Volume, and Dementia Risk: The Framingham Study. J Gerontol A Biol Sci Med Sci. 2017 Jun 01; 72(6):789-795.View Related Profiles.

Beiser, Alexa
Spartano, Nicole
Auerbach, Sanford
Seshadri, Sudha
Ramachandran, Vasan

PMID: 27422439; DOI: 10.1093/gerona/glw130;

Jensen MK, Jensen RA, Mukamal KJ, Guo X, Yao J, Sun Q, Cornelis M, Liu Y, Chen MH, Kizer JR, Djoussé L, Siscovick DS, Psaty BM, Zmuda JM, Rotter JI, Garcia M, Harris T, Chen I, Goodarzi MO, Nalls MA, Keller M, Arnold AM, Newman AB, Hoogeveen RC, Rexrode KM, Rimm EB, Hu FB, Ramachandran VS, Katz R, Pankow JS, Ix JH. Detection of genetic loci associated with plasma fetuin-A: a meta-analysis of genome-wide association studies from the CHARGE Consortium. Hum Mol Genet. 2017 Jun 01; 26(11):2156-2163. PMID: 28379451

Niiranen TJ, Lyass A, Larson MG, Hamburg NM, Benjamin EJ, Mitchell GF, Vasan RS. Prevalence, Correlates, and Prognosis of Healthy Vascular Aging in a Western Community-Dwelling Cohort: The Framingham Heart Study. Hypertension. 2017 Aug; 70(2):267-274.View Related Profiles.

Benjamin, Emelia
Larson, Martin
Hamburg, Naomi
Ramachandran, Vasan

PMID: 28559398; DOI: 10.1161/HYPERTENSIONAHA.117.09026;

Tragante V, Gho JMIH, Felix JF, Vasan RS, Smith NL, Voight BF, Palmer C, van der Harst P, Moore JH, Asselbergs FW. Gene Set Enrichment Analyses: lessons learned from the heart failure phenotype. BioData Min. 2017; 10:18. PMID: 28559929; DOI: 10.1186/s13040-017-0137-5;

Niiranen TJ, McCabe EL, Larson MG, Henglin M, Lakdawala NK, Vasan RS, Cheng S. Heritability and risks associated with early onset hypertension: multigenerational, prospective analysis in the Framingham Heart Study. BMJ. 2017 May 12; 357:j1949.View Related Profiles.

Larson, Martin
Lakdawala, Neal
Ramachandran, Vasan

PMID: 28500036

Niu J, Clancy M, Aliabadi P, Vasan R, Felson DT. Metabolic Syndrome, Its Components, and Knee Osteoarthritis: The Framingham Osteoarthritis Study. Arthritis Rheumatol. 2017 Jun; 69(6):1194-1203.View Related Profiles.

Felson, David
Niu, Jingbo
Ramachandran, Vasan

PMID: 28257604; DOI: 10.1002/art.40087;

Maillard P, Mitchell GF, Himali JJ, Beiser A, Fletcher E, Tsao CW, Pase MP, Satizabal CL, Vasan RS, Seshadri S, DeCarli C. Aortic Stiffness, Increased White Matter Free Water, and Altered Microstructural Integrity: A Continuum of Injury. Stroke. 2017 Jun; 48(6):1567-1573.View Related Profiles.

Beiser, Alexa
Satizabal, Claudia
Himali, Jayandra
Seshadri, Sudha
Ramachandran, Vasan

PMID: 28473633; DOI: 10.1161/STROKEAHA.116.016321;

Pase MP, Himali JJ, Beiser AS, Aparicio HJ, Satizabal CL, Vasan RS, Seshadri S, Jacques PF. Sugar- and Artificially Sweetened Beverages and the Risks of Incident Stroke and Dementia: A Prospective Cohort Study. Stroke. 2017 May; 48(5):1139-1146.View Related Profiles.

Beiser, Alexa
Satizabal, Claudia
Aparicio, Hugo
Himali, Jayandra
Seshadri, Sudha
Ramachandran, Vasan

PMID: 28428346; DOI: 10.1161/STROKEAHA.116.016027;

Freiberg MS, Chang CH, Skanderson M, Patterson OV, DuVall SL, Brandt CA, So-Armah KA, Vasan RS, Oursler KA, Gottdiener J, Gottlieb S, Leaf D, Rodriguez-Barradas M, Tracy RP, Gibert CL, Rimland D, Bedimo RJ, Brown ST, Goetz MB, Warner A, Crothers K, Tindle HA, Alcorn C, Bachmann JM, Justice AC, Butt AA. Association Between HIV Infection and the Risk of Heart Failure With Reduced Ejection Fraction and Preserved Ejection Fraction in the Antiretroviral Therapy Era: Results From the Veterans Aging Cohort Study. JAMA Cardiol. 2017 05 01; 2(5):536-546.View Related Profiles.

So-Armah, Kaku
Ramachandran, Vasan

PMID: 28384660; DOI: 10.1001/jamacardio.2017.0264;

Ho JE, McCabe EL, Wang TJ, Larson MG, Levy D, Tsao C, Aragam J, Mitchell GF, Benjamin EJ, Vasan RS, Cheng S. Cardiometabolic Traits and Systolic Mechanics in the Community. Circ Heart Fail. 2017 May; 10(5).View Related Profiles.

Levy, Daniel
Benjamin, Emelia
Aragam, Jayashri
Larson, Martin
Ramachandran, Vasan

PMID: 28495953

Niiranen TJ, Kalesan B, Larson MG, Hamburg NM, Benjamin EJ, Mitchell GF, Vasan RS. Aortic-Brachial Arterial Stiffness Gradient and Cardiovascular Risk in the Community: The Framingham Heart Study. Hypertension. 2017 Jun; 69(6):1022-1028.View Related Profiles.

Kalesan, Bindu
Benjamin, Emelia
Larson, Martin
Hamburg, Naomi
Ramachandran, Vasan

PMID: 28396534; DOI: 10.1161/HYPERTENSIONAHA.116.08917;

Wild PS, Felix JF, Schillert A, Teumer A, Chen MH, Leening MJG, Völker U, Großmann V, Brody JA, Irvin MR, Shah SJ, Pramana S, Lieb W, Schmidt R, Stanton AV, Malzahn D, Smith AV, Sundström J, Minelli C, Ruggiero D, Lyytikäinen LP, Tiller D, Smith JG, Monnereau C, Di Tullio MR, Musani SK, Morrison AC, Pers TH, Morley M, Kleber ME, Aragam J, Benjamin EJ, Bis JC, Bisping E, Broeckel U, Cheng S, Deckers JW, Del Greco M F, Edelmann F, Fornage M, Franke L, Friedrich N, Harris TB, Hofer E, Hofman A, Huang J, Hughes AD, Kähönen M, Investigators K, Kruppa J, Lackner KJ, Lannfelt L, Laskowski R, Launer LJ, Leosdottir M, Lin H, Lindgren CM, Loley C, MacRae CA, Mascalzoni D, Mayet J, Medenwald D, Morris AP, Müller C, Müller-Nurasyid M, Nappo S, Nilsson PM, Nuding S, Nutile T, Peters A, Pfeufer A, Pietzner D, Pramstaller PP, Raitakari OT, Rice KM, Rivadeneira F, Rotter JI, Ruohonen ST, Sacco RL, Samdarshi TE, Schmidt H, Sharp ASP, Shields DC, Sorice R, Sotoodehnia N, Stricker BH, Surendran P, Thom S, Töglhofer AM, Uitterlinden AG, Wachter R, Völzke H, Ziegler A, Münzel T, März W, Cappola TP, Hirschhorn JN, Mitchell GF, Smith NL, Fox ER, Dueker ND, Jaddoe VWV, Melander O, Russ M, Lehtimäki T, Ciullo M, Hicks AA, Lind L, Gudnason V, Pieske B, Barron AJ, Zweiker R, Schunkert H, Ingelsson E, Liu K, Arnett DK, Psaty BM, Blankenberg S, Larson MG, Felix SB, Franco OH, Zeller T, Vasan RS, Dörr M. Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function. J Clin Invest. 2017 May 01; 127(5):1798-1812.View Related Profiles.

Benjamin, Emelia
Lin, Honghuang
Aragam, Jayashri
Larson, Martin
Ramachandran, Vasan

PMID: 28394258; DOI: 10.1172/JCI84840;

Warren CR, O'Sullivan JF, Friesen M, Becker CE, Zhang X, Liu P, Wakabayashi Y, Morningstar JE, Shi X, Choi J, Xia F, Peters DT, Florido MH, Tsankov AM, Duberow E, Comisar L, Shay J, Jiang X, Meissner A, Musunuru K, Kathiresan S, Daheron L, Zhu J, Gerszten RE, Deo RC, Vasan RS, O'Donnell CJ, Cowan CA. Induced Pluripotent Stem Cell Differentiation Enables Functional Validation of GWAS Variants in Metabolic Disease. Cell Stem Cell. 2017 Apr 06; 20(4):547-557.e7.View Related Profiles.

O'Donnell, Christopher
Choi, Jihoon
Ramachandran, Vasan
Zhang, Xiaoling

PMID: 28388431; DOI: 10.1016/j.stem.2017.01.010;

Torjesen A, Cooper LL, Rong J, Larson MG, Hamburg NM, Levy D, Benjamin EJ, Vasan RS, Mitchell GF. Relations of Arterial Stiffness With Postural Change in Mean Arterial Pressure in Middle-Aged Adults: The Framingham Heart Study. Hypertension. 2017 Apr; 69(4):685-690.View Related Profiles.

Levy, Daniel
Benjamin, Emelia
Rong, Jian
Larson, Martin
Hamburg, Naomi
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PMID: 28264924; DOI: 10.1161/HYPERTENSIONAHA.116.08116;

Tripathi A, Benjamin EJ, Musani SK, Hamburg NM, Tsao CW, Saraswat A, Vasan RS, Mitchell GF, Fox ER. The association of endothelial function and tone by digital arterial tonometry with MRI left ventricular mass in African Americans: the Jackson Heart Study. J Am Soc Hypertens. 2017 May; 11(5):258-264.View Related Profiles.

Benjamin, Emelia
Hamburg, Naomi
Ramachandran, Vasan

PMID: 28412277; DOI: 10.1016/j.jash.2017.03.005;

Brant LC, Wang N, Ojeda FM, LaValley M, Barreto SM, Benjamin EJ, Mitchell GF, Vasan RS, Palmisano JN, Münzel T, Blankenberg S, Wild PS, Zeller T, Ribeiro AL, Schnabel RB, Hamburg NM. Relations of Metabolically Healthy and Unhealthy Obesity to Digital Vascular Function in Three Community-Based Cohorts: A Meta-Analysis. J Am Heart Assoc. 2017 Mar 08; 6(3).View Related Profiles.

Benjamin, Emelia
LaValley, Michael
Hamburg, Naomi
Ramachandran, Vasan

PMID: 28275071; DOI: 10.1161/JAHA.116.004199;

Pase MP, Himali JJ, Jacques PF, DeCarli C, Satizabal CL, Aparicio H, Vasan RS, Beiser AS, Seshadri S. Sugary beverage intake and preclinical Alzheimer's disease in the community. Alzheimers Dement. 2017 Sep; 13(9):955-964.View Related Profiles.

Beiser, Alexa
Satizabal, Claudia
Aparicio, Hugo
Himali, Jayandra
Seshadri, Sudha
Ramachandran, Vasan

PMID: 28274718; DOI: 10.1016/j.jalz.2017.01.024;

Park M, Hsu CY, Go AS, Feldman HI, Xie D, Zhang X, Mifflin T, Waikar SS, Sabbisetti VS, Bonventre JV, Coresh J, Nelson RG, Kimmel PL, Kusek JW, Rahman M, Schelling JR, Vasan RS, Liu KD. Urine Kidney Injury Biomarkers and Risks of Cardiovascular Disease Events and All-Cause Death: The CRIC Study. Clin J Am Soc Nephrol. 2017 May 08; 12(5):761-771.View Related Profiles.

Waikar, Sushrut
Ramachandran, Vasan

PMID: 28254771; DOI: 10.2215/CJN.08560816;

Nayor M, Larson MG, Wang N, Santhanakrishnan R, Lee DS, Tsao CW, Cheng S, Benjamin EJ, Vasan RS, Levy D, Fox CS, Ho JE. The association of chronic kidney disease and microalbuminuria with heart failure with preserved vs. reduced ejection fraction. Eur J Heart Fail. 2017 May; 19(5):615-623.View Related Profiles.

Benjamin, Emelia
Larson, Martin
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Ramachandran, Vasan

PMID: 28217978; DOI: 10.1002/ejhf.778;

Christiansen MN, Køber L, Weeke P, Vasan RS, Jeppesen JL, Smith JG, Gislason GH, Torp-Pedersen C, Andersson C. Age-Specific Trends in Incidence, Mortality, and Comorbidities of Heart Failure in Denmark, 1995 to 2012. Circulation. 2017 Mar 28; 135(13):1214-1223. PMID: 28174193; DOI: 10.1161/CIRCULATIONAHA.116.025941;

Dufouil C, Beiser A, McLure LA, Wolf PA, Tzourio C, Howard VJ, Westwood AJ, Himali JJ, Sullivan L, Aparicio HJ, Kelly-Hayes M, Ritchie K, Kase CS, Pikula A, Romero JR, D'Agostino RB, Samieri C, Vasan RS, Chêne G, Howard G, Seshadri S. Revised Framingham Stroke Risk Profile to Reflect Temporal Trends. Circulation. 2017 Mar 21; 135(12):1145-1159.View Related Profiles.

Beiser, Alexa
Kase, Carlos
Aparicio, Hugo
Himali, Jayandra
Romero, Jose
Sullivan, Lisa
Wolf, Philip
D'Agostino, Ralph
Seshadri, Sudha
Ramachandran, Vasan

PMID: 28159800; DOI: 10.1161/CIRCULATIONAHA.115.021275;

Romero JR, Preis SR, Beiser A, Himali JJ, Shoamanesh A, Wolf PA, Kase CS, Vasan RS, DeCarli C, Seshadri S. Cerebral Microbleeds as Predictors of Mortality: The Framingham Heart Study. Stroke. 2017 Mar; 48(3):781-783.View Related Profiles.

Beiser, Alexa
Shoamanesh, Ashkan
Kase, Carlos
Himali, Jayandra
Romero, Jose
Wolf, Philip
Preis, Sarah
Seshadri, Sudha
Ramachandran, Vasan

PMID: 28143923; DOI: 10.1161/STROKEAHA.116.015354;

Parikh NI, Norberg M, Ingelsson E, Cnattingius S, Vasan RS, Domellöf M, Jansson JH, Edstedt Bonamy AK. Association of Pregnancy Complications and Characteristics With Future Risk of Elevated Blood Pressure: The Västerbotten Intervention Program. Hypertension. 2017 Mar; 69(3):475-483. PMID: 28137991; DOI: 10.1161/HYPERTENSIONAHA.116.08121;

Spartano NL, Stevenson MD, Xanthakis V, Larson MG, Andersson C, Murabito JM, Vasan RS. Associations of objective physical activity with insulin sensitivity and circulating adipokine profile: the Framingham Heart Study. Clin Obes. 2017 Apr; 7(2):59-69.View Related Profiles.

Murabito, Joanne
Larson, Martin
Spartano, Nicole
Xanthakis, Vanessa
Ramachandran, Vasan

PMID: 28112860; DOI: 10.1111/cob.12177;

Bell V, McCabe EL, Larson MG, Rong J, Merz AA, Osypiuk E, Lehman BT, Stantchev P, Aragam J, Benjamin EJ, Hamburg NM, Vasan RS, Mitchell GF, Cheng S. Relations Between Aortic Stiffness and Left Ventricular Mechanical Function in the Community. J Am Heart Assoc. 2017 Jan 09; 6(1).View Related Profiles.

Benjamin, Emelia
Osypiuk, Ewa
Aragam, Jayashri
Larson, Martin
Hamburg, Naomi
Ramachandran, Vasan

PMID: 28069573; DOI: 10.1161/JAHA.116.004903;

Weinstein G, Preis SR, Beiser AS, Kaess B, Chen TC, Satizabal C, Rahman F, Benjamin EJ, Vasan RS, Seshadri S. Clinical and Environmental Correlates of Serum BDNF: A Descriptive Study with Plausible Implications for AD Research. Curr Alzheimer Res. 2017; 14(7):722-730.View Related Profiles.

Beiser, Alexa
Satizabal, Claudia
Benjamin, Emelia
Weinstein, Galit
Preis, Sarah
Seshadri, Sudha
Ramachandran, Vasan

PMID: 28164772; DOI: 10.2174/1567205014666170203094520;

Noordam R, Sitlani CM, Avery CL, Stewart JD, Gogarten SM, Wiggins KL, Trompet S, Warren HR, Sun F, Evans DS, Li X, Li J, Smith AV, Bis JC, Brody JA, Busch EL, Caulfield MJ, Chen YI, Cummings SR, Cupples LA, Duan Q, Franco OH, Méndez-Giráldez R, Harris TB, Heckbert SR, van Heemst D, Hofman A, Floyd JS, Kors JA, Launer LJ, Li Y, Li-Gao R, Lange LA, Lin HJ, de Mutsert R, Napier MD, Newton-Cheh C, Poulter N, Reiner AP, Rice KM, Roach J, Rodriguez CJ, Rosendaal FR, Sattar N, Sever P, Seyerle AA, Slagboom PE, Soliman EZ, Sotoodehnia N, Stott DJ, Stürmer T, Taylor KD, Thornton TA, Uitterlinden AG, Wilhelmsen KC, Wilson JG, Gudnason V, Jukema JW, Laurie CC, Liu Y, Mook-Kanamori DO, Munroe PB, Rotter JI, Vasan RS, Psaty BM, Stricker BH, Whitsel EA. A genome-wide interaction analysis of tricyclic/tetracyclic antidepressants and RR and QT intervals: a pharmacogenomics study from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium. J Med Genet. 2017 May; 54(5):313-323.View Related Profiles.

Sun, Fangui
Cupples, L
Ramachandran, Vasan

PMID: 28039329; DOI: 10.1136/jmedgenet-2016-104112;

Emdin CA, Khera AV, Natarajan P, Klarin D, Won HH, Peloso GM, Stitziel NO, Nomura A, Zekavat SM, Bick AG, Gupta N, Asselta R, Duga S, Merlini PA, Correa A, Kessler T, Wilson JG, Bown MJ, Hall AS, Braund PS, Samani NJ, Schunkert H, Marrugat J, Elosua R, McPherson R, Farrall M, Watkins H, Willer C, Abecasis GR, Felix JF, Vasan RS, Lander E, Rader DJ, Danesh J, Ardissino D, Gabriel S, Saleheen D, Kathiresan S. Phenotypic Characterization of Genetically Lowered Human Lipoprotein(a) Levels. J Am Coll Cardiol. 2016 Dec 27; 68(25):2761-2772.View Related Profiles.

Peloso, Gina
Ramachandran, Vasan

PMID: 28007139; DOI: 10.1016/j.jacc.2016.10.033;

Chatterjee R, Davenport CA, Svetkey LP, Batch BC, Lin PH, Ramachandran VS, Fox ER, Harman J, Yeh HC, Selvin E, Correa A, Butler K, Edelman D. Serum potassium is a predictor of incident diabetes in African Americans with normal aldosterone: the Jackson Heart Study. Am J Clin Nutr. 2017 Feb; 105(2):442-449. PMID: 27974310; DOI: 10.3945/ajcn.116.143255;

Li M, Li Y, Weeks O, Mijatovic V, Teumer A, Huffman JE, Tromp G, Fuchsberger C, Gorski M, Lyytikäinen LP, Nutile T, Sedaghat S, Sorice R, Tin A, Yang Q, Ahluwalia TS, Arking DE, Bihlmeyer NA, Böger CA, Carroll RJ, Chasman DI, Cornelis MC, Dehghan A, Faul JD, Feitosa MF, Gambaro G, Gasparini P, Giulianini F, Heid I, Huang J, Imboden M, Jackson AU, Jeff J, Jhun MA, Katz R, Kifley A, Kilpeläinen TO, Kumar A, Laakso M, Li-Gao R, Lohman K, Lu Y, Mägi R, Malerba G, Mihailov E, Mohlke KL, Mook-Kanamori DO, Robino A, Ruderfer D, Salvi E, Schick UM, Schulz CA, Smith AV, Smith JA, Traglia M, Yerges-Armstrong LM, Zhao W, Goodarzi MO, Kraja AT, Liu C, Wessel J, Boerwinkle E, Borecki IB, Bork-Jensen J, Bottinger EP, Braga D, Brandslund I, Brody JA, Campbell A, Carey DJ, Christensen C, Coresh J, Crook E, Curhan GC, Cusi D, de Boer IH, de Vries AP, Denny JC, Devuyst O, Dreisbach AW, Endlich K, Esko T, Franco OH, Fulop T, Gerhard GS, Glümer C, Gottesman O, Grarup N, Gudnason V, Hansen T, Harris TB, Hayward C, Hocking L, Hofman A, Hu FB, Husemoen LL, Jackson RD, Jørgensen T, Jørgensen ME, Kähönen M, Kardia SL, König W, Kooperberg C, Kriebel J, Launer LJ, Lauritzen T, Lehtimäki T, Levy D, Linksted P, Linneberg A, Liu Y, Loos RJ, Lupo A, Meisinger C, Melander O, Metspalu A, Mitchell P, Nauck M, Nürnberg P, Orho-Melander M, Parsa A, Pedersen O, Peters A, Peters U, Polasek O, Porteous D, Probst-Hensch NM, Psaty BM, Qi L, Raitakari OT, Reiner AP, Rettig R, Ridker PM, Rivadeneira F, Rossouw JE, Schmidt F, Siscovick D, Soranzo N, Strauch K, Toniolo D, Turner ST, Uitterlinden AG, Ulivi S, Velayutham D, Völker U, Völzke H, Waldenberger M, Wang JJ, Weir DR, Witte D, Kuivaniemi H, Fox CS, Franceschini N, Goessling W, Köttgen A, Chu AY. SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function. J Am Soc Nephrol. 2017 Mar; 28(3):981-994.View Related Profiles.

Liu, Chunyu
Cupples, L
Yang, Qiong
Ramachandran, Vasan

PMID: 27920155; DOI: 10.1681/ASN.2016020131;

Mitchell GF, Hwang SJ, Larson MG, Hamburg NM, Benjamin EJ, Vasan RS, Levy D, Vita JA. Reply. J Hypertens. 2016 12; 34(12):2489-2490.View Related Profiles.

Levy, Daniel
Benjamin, Emelia
Larson, Martin
Hamburg, Naomi
Hwang, Shih-Jen
Ramachandran, Vasan

PMID: 27805916

Cooper LL, Palmisano JN, Benjamin EJ, Larson MG, Vasan RS, Mitchell GF, Hamburg NM. Microvascular Function Contributes to the Relation Between Aortic Stiffness and Cardiovascular Events: The Framingham Heart Study. Circ Cardiovasc Imaging. 2016 Dec; 9(12).View Related Profiles.

Benjamin, Emelia
Larson, Martin
Hamburg, Naomi
Ramachandran, Vasan

PMID: 27956408

Wang H, Cade BE, Chen H, Gleason KJ, Saxena R, Feng T, Larkin EK, Vasan RS, Lin H, Patel SR, Tracy RP, Liu Y, Gottlieb DJ, Below JE, Hanis CL, Petty LE, Sunyaev SR, Frazier-Wood AC, Rotter JI, Post W, Lin X, Redline S, Zhu X. Variants in angiopoietin-2 (ANGPT2) contribute to variation in nocturnal oxyhaemoglobin saturation level. Hum Mol Genet. 2016 Dec 01; 25(23):5244-5253.View Related Profiles.

Lin, Honghuang
Ramachandran, Vasan

PMID: 27798093; DOI: 10.1093/hmg/ddw324;

Andersson C, Vasan RS. Intensive vs Standard Blood Pressure Control for Older Adults. JAMA. 2016 Nov 08; 316(18):1922-1923. PMID: 27825004; DOI: 10.1001/jama.2016.14927;

Bozkurt B, Colvin M, Cook J, Cooper LT, Deswal A, Fonarow GC, Francis GS, Lenihan D, Lewis EF, McNamara DM, Pahl E, Vasan RS, Ramasubbu K, Rasmusson K, Towbin JA, Yancy C. Current Diagnostic and Treatment Strategies for Specific Dilated Cardiomyopathies: A Scientific Statement From the American Heart Association. Circulation. 2016 12 06; 134(23):e579-e646. PMID: 27832612

Hsu CY, Xie D, Waikar SS, Bonventre JV, Zhang X, Sabbisetti V, Mifflin TE, Coresh J, Diamantidis CJ, He J, Lora CM, Miller ER, Nelson RG, Ojo AO, Rahman M, Schelling JR, Wilson FP, Kimmel PL, Feldman HI, Vasan RS, Liu KD. Urine biomarkers of tubular injury do not improve on the clinical model predicting chronic kidney disease progression. Kidney Int. 2017 Jan; 91(1):196-203.View Related Profiles.

Waikar, Sushrut
Ramachandran, Vasan

PMID: 28029431; DOI: 10.1016/j.kint.2016.09.003;

Bretón-Romero R, Wang N, Palmisano J, Larson MG, Vasan RS, Mitchell GF, Benjamin EJ, Vita JA, Hamburg NM. Cross-Sectional Associations of Flow Reversal, Vascular Function, and Arterial Stiffness in the Framingham Heart Study. Arterioscler Thromb Vasc Biol. 2016 Dec; 36(12):2452-2459.View Related Profiles.

Benjamin, Emelia
Larson, Martin
Hamburg, Naomi
Breton-Romero, Rosa
Ramachandran, Vasan

PMID: 27789476

Niiranen TJ, Kalesan B, Hamburg NM, Benjamin EJ, Mitchell GF, Vasan RS. Relative Contributions of Arterial Stiffness and Hypertension to Cardiovascular Disease: The Framingham Heart Study. J Am Heart Assoc. 2016 Oct 26; 5(11).View Related Profiles.

Kalesan, Bindu
Benjamin, Emelia
Hamburg, Naomi
Ramachandran, Vasan

PMID: 27912210

Rahman F, Himali JJ, Yin X, Beiser AS, Ellinor PT, Lubitz SA, Vasan RS, Magnani JW, McManus DD, Seshadri S, Benjamin EJ. Serum brain-derived neurotrophic factor and risk of atrial fibrillation. Am Heart J. 2017 Jan; 183:69-73.View Related Profiles.

Beiser, Alexa
Benjamin, Emelia
Himali, Jayandra
Seshadri, Sudha
Ramachandran, Vasan

PMID: 27979044; DOI: 10.1016/j.ahj.2016.07.027;

Tsao CW, Vasan RS. Reply: Size Matters? Seeking High-Risk Populations Among "Normal" Individuals. JACC Heart Fail. 2016 10; 4(10):828-829. PMID: 27686927; DOI: 10.1016/j.jchf.2016.06.009;

Zhang W, Jernerén F, Lehne BC, Chen MH, Luben RN, Johnston C, Elshorbagy A, Eppinga RN, Scott WR, Adeyeye E, Scott J, Böger RH, Khaw KT, van der Harst P, Wareham NJ, Vasan RS, Chambers JC, Refsum H, Kooner JS. Genome-wide association reveals that common genetic variation in the kallikrein-kinin system is associated with serum L-arginine levels. Thromb Haemost. 2016 Nov 30; 116(6):1041-1049. PMID: 27656708; DOI: 10.1160/TH16-02-0151;

McManus DD, Yin X, Gladstone R, Vittinghoff E, Vasan RS, Larson MG, Benjamin EJ, Marcus GM. Alcohol Consumption, Left Atrial Diameter, and Atrial Fibrillation. J Am Heart Assoc. 2016 Sep 14; 5(9).View Related Profiles.

Benjamin, Emelia
Larson, Martin
Ramachandran, Vasan

PMID: 27628571; DOI: 10.1161/JAHA.116.004060;

Liu C, Kraja AT, Smith JA, Brody JA, Franceschini N, Bis JC, Rice K, Morrison AC, Lu Y, Weiss S, Guo X, Palmas W, Martin LW, Chen YD, Surendran P, Drenos F, Cook JP, Auer PL, Chu AY, Giri A, Zhao W, Jakobsdottir J, Lin LA, Stafford JM, Amin N, Mei H, Yao J, Voorman A, Larson MG, Grove ML, Smith AV, Hwang SJ, Chen H, Huan T, Kosova G, Stitziel NO, Kathiresan S, Samani N, Schunkert H, Deloukas P, Li M, Fuchsberger C, Pattaro C, Gorski M, Kooperberg C, Papanicolaou GJ, Rossouw JE, Faul JD, Kardia SL, Bouchard C, Raffel LJ, Uitterlinden AG, Franco OH, Vasan RS, O'Donnell CJ, Taylor KD, Liu K, Bottinger EP, Gottesman O, Daw EW, Giulianini F, Ganesh S, Salfati E, Harris TB, Launer LJ, Dörr M, Felix SB, Rettig R, Völzke H, Kim E, Lee WJ, Lee IT, Sheu WH, Tsosie KS, Edwards DR, Liu Y, Correa A, Weir DR, Völker U, Ridker PM, Boerwinkle E, Gudnason V, Reiner AP, van Duijn CM, Borecki IB, Edwards TL, Chakravarti A, Rotter JI, Psaty BM, Loos RJ, Fornage M, Ehret GB, Newton-Cheh C, Levy D, Chasman DI. Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci. Nat Genet. 2016 Oct; 48(10):1162-70.View Related Profiles.

O'Donnell, Christopher
Liu, Chunyu
Larson, Martin
Hwang, Shih-Jen
Ramachandran, Vasan

PMID: 27618448; DOI: 10.1038/ng.3660;

Ehret GB, Ferreira T, Chasman DI, Jackson AU, Schmidt EM, Johnson T, Thorleifsson G, Luan J, Donnelly LA, Kanoni S, Petersen AK, Pihur V, Strawbridge RJ, Shungin D, Hughes MF, Meirelles O, Kaakinen M, Bouatia-Naji N, Kristiansson K, Shah S, Kleber ME, Guo X, Lyytikäinen LP, Fava C, Eriksson N, Nolte IM, Magnusson PK, Salfati EL, Rallidis LS, Theusch E, Smith AJ, Folkersen L, Witkowska K, Pers TH, Joehanes R, Kim SK, Lataniotis L, Jansen R, Johnson AD, Warren H, Kim YJ, Zhao W, Wu Y, Tayo BO, Bochud M, Absher D, Adair LS, Amin N, Arking DE, Axelsson T, Baldassarre D, Balkau B, Bandinelli S, Barnes MR, Barroso I, Bevan S, Bis JC, Bjornsdottir G, Boehnke M, Boerwinkle E, Bonnycastle LL, Boomsma DI, Bornstein SR, Brown MJ, Burnier M, Cabrera CP, Chambers JC, Chang IS, Cheng CY, Chines PS, Chung RH, Collins FS, Connell JM, Döring A, Dallongeville J, Danesh J, de Faire U, Delgado G, Dominiczak AF, Doney AS, Drenos F, Edkins S, Eicher JD, Elosua R, Enroth S, Erdmann J, Eriksson P, Esko T, Evangelou E, Evans A, Fall T, Farrall M, Felix JF, Ferrières J, Ferrucci L, Fornage M, Forrester T, Franceschini N, Franco OH, Franco-Cereceda A, Fraser RM, Ganesh SK, Gao H, Gertow K, Gianfagna F, Gigante B, Giulianini F, Goel A, Goodall AH, Goodarzi MO, Gorski M, Gräßler J, Groves CJ, Gudnason V, Gyllensten U, Hallmans G, Hartikainen AL, Hassinen M, Havulinna AS, Hayward C, Hercberg S, Herzig KH, Hicks AA, Hingorani AD, Hirschhorn JN, Hofman A, Holmen J, Holmen OL, Hottenga JJ, Howard P, Hsiung CA, Hunt SC, Ikram MA, Illig T, Iribarren C, Jensen RA, Kähönen M, Kang HM, Kathiresan S, Keating BJ, Khaw KT, Kim YK, Kim E, Kivimaki M, Klopp N, Kolovou G, Komulainen P, Kooner JS, Kosova G, Krauss RM, Kuh D, Kutalik Z, Kuusisto J, Kvaløy K, Lakka TA, Lee NR, Lee IT, Lee WJ, Levy D, Li X, Liang KW, Lin H, Lin L, Lindström J, Lobbens S, Männistö S, Müller G, Müller-Nurasyid M, Mach F, Markus HS, Marouli E, McCarthy MI, McKenzie CA, Meneton P, Menni C, Metspalu A, Mijatovic V, Moilanen L, Montasser ME, Morris AD, Morrison AC, Mulas A, Nagaraja R, Narisu N, Nikus K, O'Donnell CJ, O'Reilly PF, Ong KK, Paccaud F, Palmer CD, Parsa A, Pedersen NL, Penninx BW, Perola M, Peters A, Poulter N, Pramstaller PP, Psaty BM, Quertermous T, Rao DC, Rasheed A, Rayner NW, Renström F, Rettig R, Rice KM, Roberts R, Rose LM, Rossouw J, Samani NJ, Sanna S, Saramies J, Schunkert H, Sebert S, Sheu WH, Shin YA, Sim X, Smit JH, Smith AV, Sosa MX, Spector TD, Stancáková A, Stanton AV, Stirrups KE, Stringham HM, Sundstrom J, Swift AJ, Syvänen AC, Tai ES, Tanaka T, Tarasov KV, Teumer A, Thorsteinsdottir U, Tobin MD, Tremoli E, Uitterlinden AG, Uusitupa M, Vaez A, Vaidya D, van Duijn CM, van Iperen EP, Vasan RS, Verwoert GC, Virtamo J, Vitart V, Voight BF, Vollenweider P, Wagner A, Wain LV, Wareham NJ, Watkins H, Weder AB, Westra HJ, Wilks R, Wilsgaard T, Wilson JF, Wong TY, Yang TP, Yao J, Yengo L, Zhang W, Zhao JH, Zhu X, Bovet P, Cooper RS, Mohlke KL, Saleheen D, Lee JY, Elliott P, Gierman HJ, Willer CJ, Franke L, Hovingh GK, Taylor KD, Dedoussis G, Sever P, Wong A, Lind L, Assimes TL, Njølstad I, Schwarz PE, Langenberg C, Snieder H, Caulfield MJ, Melander O, Laakso M, Saltevo J, Rauramaa R, Tuomilehto J, Ingelsson E, Lehtimäki T, Hveem K, Palmas W, März W, Kumari M, Salomaa V, Chen YD, Rotter JI, Froguel P, Jarvelin MR, Lakatta EG, Kuulasmaa K, Franks PW, Hamsten A, Wichmann HE, Palmer CN, Stefansson K, Ridker PM, Loos RJ, Chakravarti A, Deloukas P, Morris AP, Newton-Cheh C, Munroe PB. The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals. Nat Genet. 2016 Oct; 48(10):1171-84.View Related Profiles.

O'Donnell, Christopher
Lin, Honghuang
Ramachandran, Vasan

PMID: 27618452; DOI: 10.1038/ng.3667;

Surendran P, Drenos F, Young R, Warren H, Cook JP, Manning AK, Grarup N, Sim X, Barnes DR, Witkowska K, Staley JR, Tragante V, Tukiainen T, Yaghootkar H, Masca N, Freitag DF, Ferreira T, Giannakopoulou O, Tinker A, Harakalova M, Mihailov E, Liu C, Kraja AT, Nielsen SF, Rasheed A, Samuel M, Zhao W, Bonnycastle LL, Jackson AU, Narisu N, Swift AJ, Southam L, Marten J, Huyghe JR, Stancáková A, Fava C, Ohlsson T, Matchan A, Stirrups KE, Bork-Jensen J, Gjesing AP, Kontto J, Perola M, Shaw-Hawkins S, Havulinna AS, Zhang H, Donnelly LA, Groves CJ, Rayner NW, Neville MJ, Robertson NR, Yiorkas AM, Herzig KH, Kajantie E, Zhang W, Willems SM, Lannfelt L, Malerba G, Soranzo N, Trabetti E, Verweij N, Evangelou E, Moayyeri A, Vergnaud AC, Nelson CP, Poveda A, Varga TV, Caslake M, de Craen AJ, Trompet S, Luan J, Scott RA, Harris SE, Liewald DC, Marioni R, Menni C, Farmaki AE, Hallmans G, Renström F, Huffman JE, Hassinen M, Burgess S, Vasan RS, Felix JF, Uria-Nickelsen M, Malarstig A, Reilly DF, Hoek M, Vogt TF, Lin H, Lieb W, Traylor M, Markus HS, Highland HM, Justice AE, Marouli E, Lindström J, Uusitupa M, Komulainen P, Lakka TA, Rauramaa R, Polasek O, Rudan I, Rolandsson O, Franks PW, Dedoussis G, Spector TD, Jousilahti P, Männistö S, Deary IJ, Starr JM, Langenberg C, Wareham NJ, Brown MJ, Dominiczak AF, Connell JM, Jukema JW, Sattar N, Ford I, Packard CJ, Esko T, Mägi R, Metspalu A, de Boer RA, van der Meer P, van der Harst P, Gambaro G, Ingelsson E, Lind L, de Bakker PI, Numans ME, Brandslund I, Christensen C, Petersen ER, Korpi-Hyövälti E, Oksa H, Chambers JC, Kooner JS, Blakemore AI, Franks S, Jarvelin MR, Husemoen LL, Linneberg A, Skaaby T, Thuesen B, Karpe F, Tuomilehto J, Doney AS, Morris AD, Palmer CN, Holmen OL, Hveem K, Willer CJ, Tuomi T, Groop L, Käräjämäki A, Palotie A, Ripatti S, Salomaa V, Alam DS, Majumder AA, Di Angelantonio E, Chowdhury R, McCarthy MI, Poulter N, Stanton AV, Sever P, Amouyel P, Arveiler D, Blankenberg S, Ferrières J, Kee F, Kuulasmaa K, Müller-Nurasyid M, Veronesi G, Virtamo J, Deloukas P, Elliott P, Zeggini E, Kathiresan S, Melander O, Kuusisto J, Laakso M, Padmanabhan S, Porteous DJ, Hayward C, Scotland G, Collins FS, Mohlke KL, Hansen T, Pedersen O, Boehnke M, Stringham HM, Frossard P, Newton-Cheh C, Tobin MD, Nordestgaard BG, Caulfield MJ, Mahajan A, Morris AP, Tomaszewski M, Samani NJ, Saleheen D, Asselbergs FW, Lindgren CM, Danesh J, Wain LV, Butterworth AS, Howson JM, Munroe PB. Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension. Nat Genet. 2016 Oct; 48(10):1151-61.View Related Profiles.

Liu, Chunyu
Lin, Honghuang
Ramachandran, Vasan

PMID: 27618447; DOI: 10.1038/ng.3654;

Lorbeer R, Baumeister SE, Dörr M, Nauck M, Grotevendt A, Schlesinger S, Teumer A, Völzke H, Grabe HJ, Wallaschofski H, Vasan RS, Lieb W. Angiopoietin-2, its soluble receptor Tie-2, and metabolic syndrome components in a population-based sample. Obesity (Silver Spring). 2016 Oct; 24(10):2038-41. PMID: 27601273; DOI: 10.1002/oby.21632;

Meneton P, Lemogne C, Herquelot E, Bonenfant S, Larson MG, Vasan RS, Ménard J, Goldberg M, Zins M. A Global View of the Relationships between the Main Behavioural and Clinical Cardiovascular Risk Factors in the GAZEL Prospective Cohort. PLoS One. 2016; 11(9):e0162386.View Related Profiles.

Larson, Martin
Ramachandran, Vasan

PMID: 27598908; PMCID: PMC5012694; DOI: 10.1371/journal.pone.0162386;

Postmus I, Warren HR, Trompet S, Arsenault BJ, Avery CL, Bis JC, Chasman DI, de Keyser CE, Deshmukh HA, Evans DS, Feng Q, Li X, Smit RA, Smith AV, Sun F, Taylor KD, Arnold AM, Barnes MR, Barratt BJ, Betteridge J, Boekholdt SM, Boerwinkle E, Buckley BM, Chen YI, de Craen AJ, Cummings SR, Denny JC, Dubé MP, Durrington PN, Eiriksdottir G, Ford I, Guo X, Harris TB, Heckbert SR, Hofman A, Hovingh GK, Kastelein JJ, Launer LJ, Liu CT, Liu Y, Lumley T, McKeigue PM, Munroe PB, Neil A, Nickerson DA, Nyberg F, O'Brien E, O'Donnell CJ, Post W, Poulter N, Vasan RS, Rice K, Rich SS, Rivadeneira F, Sattar N, Sever P, Shaw-Hawkins S, Shields DC, Slagboom PE, Smith NL, Smith JD, Sotoodehnia N, Stanton A, Stott DJ, Stricker BH, Stürmer T, Uitterlinden AG, Wei WQ, Westendorp RG, Whitsel EA, Wiggins KL, Wilke RA, Ballantyne CM, Colhoun HM, Cupples LA, Franco OH, Gudnason V, Hitman G, Palmer CN, Psaty BM, Ridker PM, Stafford JM, Stein CM, Tardif JC, Caulfield MJ, Jukema JW, Rotter JI, Krauss RM. Meta-analysis of genome-wide association studies of HDL cholesterol response to statins. J Med Genet. 2016 Dec; 53(12):835-845.View Related Profiles.

Liu, Ching-Ti
O'Donnell, Christopher
Sun, Fangui
Cupples, L
Ramachandran, Vasan

PMID: 27587472; DOI: 10.1136/jmedgenet-2016-103966;

Shoamanesh A, Preis SR, Beiser AS, Kase CS, Wolf PA, Vasan RS, Benjamin EJ, Seshadri S, Romero JR. Circulating biomarkers and incident ischemic stroke in the Framingham Offspring Study. Neurology. 2016 Sep 20; 87(12):1206-11.View Related Profiles.

Beiser, Alexa
Shoamanesh, Ashkan
Kase, Carlos
Benjamin, Emelia
Romero, Jose
Wolf, Philip
Preis, Sarah
Seshadri, Sudha
Ramachandran, Vasan

PMID: 27558379; DOI: 10.1212/WNL.0000000000003115;

Ko D, Riles EM, Marcos EG, Magnani JW, Lubitz SA, Lin H, Long MT, Schnabel RB, McManus DD, Ellinor PT, Ramachandran VS, Wang TJ, Gerszten RE, Benjamin EJ, Yin X, Rienstra M. Metabolomic Profiling in Relation to New-Onset Atrial Fibrillation (from the Framingham Heart Study). Am J Cardiol. 2016 Nov 15; 118(10):1493-1496.View Related Profiles.

Ko, Darae
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Lin, Honghuang
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PMID: 27666170; DOI: 10.1016/j.amjcard.2016.08.010;

Pase MP, Beiser A, Himali JJ, Tsao C, Satizabal CL, Vasan RS, Seshadri S, Mitchell GF. Aortic Stiffness and the Risk of Incident Mild Cognitive Impairment and Dementia. Stroke. 2016 Sep; 47(9):2256-61.View Related Profiles.

Beiser, Alexa
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PMID: 27491735; PMCID: PMC4995162; DOI: 10.1161/STROKEAHA.116.013508;

Mitchell GF, Hwang SJ, Larson MG, Hamburg NM, Benjamin EJ, Vasan RS, Levy D, Vita JA. Transfer function-derived central pressure and cardiovascular disease events: the Framingham Heart Study. J Hypertens. 2016 Aug; 34(8):1528-34.View Related Profiles.

Levy, Daniel
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PMID: 27219486; DOI: 10.1097/HJH.0000000000000968;

Dhingra R, Vasan RS. Biomarkers in cardiovascular disease: Statistical assessment and section on key novel heart failure biomarkers. Trends Cardiovasc Med. 2017 Feb; 27(2):123-133. PMID: 27576060; DOI: 10.1016/j.tcm.2016.07.005;

Ngo D, Sinha S, Shen D, Kuhn EW, Keyes MJ, Shi X, Benson MD, O'Sullivan JF, Keshishian H, Farrell LA, Fifer MA, Vasan RS, Sabatine MS, Larson MG, Carr SA, Wang TJ, Gerszten RE. Aptamer-Based Proteomic Profiling Reveals Novel Candidate Biomarkers and Pathways in Cardiovascular Disease. Circulation. 2016 Jul 26; 134(4):270-85.View Related Profiles.

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PMID: 27444932; PMCID: PMC4963294; DOI: 10.1161/CIRCULATIONAHA.116.021803;

Rhee EP, Yang Q, Yu B, Liu X, Cheng S, Deik A, Pierce KA, Bullock K, Ho JE, Levy D, Florez JC, Kathiresan S, Larson MG, Vasan RS, Clish CB, Wang TJ, Boerwinkle E, O'Donnell CJ, Gerszten RE. An exome array study of the plasma metabolome. Nat Commun. 2016 07 25; 7:12360.View Related Profiles.

O'Donnell, Christopher
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PMID: 27453504; DOI: 10.1038/ncomms12360;

Andersson C, Quiroz R, Enserro D, Larson MG, Hamburg NM, Vita JA, Levy D, Benjamin EJ, Mitchell GF, Vasan RS. Association of Parental Hypertension With Arterial Stiffness in Nonhypertensive Offspring: The Framingham Heart Study. Hypertension. 2016 Sep; 68(3):584-9.View Related Profiles.

Levy, Daniel
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PMID: 27456526; PMCID: PMC5002314; DOI: 10.1161/HYPERTENSIONAHA.116.07426;

Shaikh AY, Wang N, Yin X, Larson MG, Vasan RS, Hamburg NM, Magnani JW, Ellinor PT, Lubitz SA, Mitchell GF, Benjamin EJ, McManus DD. Relations of Arterial Stiffness and Brachial Flow-Mediated Dilation With New-Onset Atrial Fibrillation: The Framingham Heart Study. Hypertension. 2016 Sep; 68(3):590-6.View Related Profiles.

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PMID: 27456517; DOI: 10.1161/HYPERTENSIONAHA.116.07650;

Puurunen MK, Enserro D, Xanthakis V, Larson MG, Benjamin EJ, Tofler GH, Wollert KC, O'Donnell CJ, Vasan RS. Biomarkers for the prediction of venous thromboembolism in the community. Thromb Res. 2016 Sep; 145:34-9.View Related Profiles.

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PMID: 27447083; DOI: 10.1016/j.thromres.2016.07.006;

Rahman F, Yin X, Larson MG, Ellinor PT, Lubitz SA, Vasan RS, McManus DD, Magnani JW, Benjamin EJ. Trajectories of Risk Factors and Risk of New-Onset Atrial Fibrillation in the Framingham Heart Study. Hypertension. 2016 Sep; 68(3):597-605.View Related Profiles.

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PMID: 27512109; PMCID: PMC4982514; DOI: 10.1161/HYPERTENSIONAHA.116.07683;

Xanthakis V, Enserro DM, Larson MG, Wollert KC, Januzzi JL, Levy D, Aragam J, Benjamin EJ, Cheng S, Wang TJ, Mitchell GF, Vasan RS. Prevalence, Neurohormonal Correlates, and Prognosis of Heart Failure Stages in the Community. JACC Heart Fail. 2016 Oct; 4(10):808-815.View Related Profiles.

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PMID: 27395350; DOI: 10.1016/j.jchf.2016.05.001;

Haring R, Enserro D, Xanthakis V, Mitchell GF, Benjamin EJ, Hamburg NM, Sullivan L, Nauck M, Wallaschofski H, Vasan RS. Plasma Fibroblast Growth Factor 23: Clinical Correlates and Association With Cardiovascular Disease and Mortality in the Framingham Heart Study. J Am Heart Assoc. 2016 Jul 06; 5(7).View Related Profiles.

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PMID: 27385427; DOI: 10.1161/JAHA.116.003486;

Kaess BM, Preis SR, Beiser A, Sawyer DB, Chen TC, Seshadri S, Vasan RS. Circulating vascular endothelial growth factor and the risk of cardiovascular events. Heart. 2016 Dec 01; 102(23):1898-1901.View Related Profiles.

Beiser, Alexa
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PMID: 27354275; DOI: 10.1136/heartjnl-2015-309155;

Teumer A, Qi Q, Nethander M, Aschard H, Bandinelli S, Beekman M, Berndt SI, Bidlingmaier M, Broer L, Cappola A, Ceda GP, Chanock S, Chen MH, Chen TC, Chen YD, Chung J, Del Greco Miglianico F, Eriksson J, Ferrucci L, Friedrich N, Gnewuch C, Goodarzi MO, Grarup N, Guo T, Hammer E, Hayes RB, Hicks AA, Hofman A, Houwing-Duistermaat JJ, Hu F, Hunter DJ, Husemoen LL, Isaacs A, Jacobs KB, Janssen JA, Jansson JO, Jehmlich N, Johnson S, Juul A, Karlsson M, Kilpelainen TO, Kovacs P, Kraft P, Li C, Linneberg A, Liu Y, Loos RJ, Lorentzon M, Lu Y, Maggio M, Magi R, Meigs J, Mellström D, Nauck M, Newman AB, Pollak MN, Pramstaller PP, Prokopenko I, Psaty BM, Reincke M, Rimm EB, Rotter JI, Saint Pierre A, Schurmann C, Seshadri S, Sjögren K, Slagboom PE, Strickler HD, Stumvoll M, Suh Y, Sun Q, Zhang C, Svensson J, Tanaka T, Tare A, Tönjes A, Uh HW, van Duijn CM, van Heemst D, Vandenput L, Vasan RS, Völker U, Willems SM, Ohlsson C, Wallaschofski H, Kaplan RC. Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits. Aging Cell. 2016 Oct; 15(5):811-24.View Related Profiles.

Seshadri, Sudha
Ramachandran, Vasan

PMID: 27329260; DOI: 10.1111/acel.12490;

MacRae CA, Vasan RS. The Future of Genetics and Genomics: Closing the Phenotype Gap in Precision Medicine. Circulation. 2016 Jun 21; 133(25):2634-9. PMID: 27324359; DOI: 10.1161/CIRCULATIONAHA.116.022547;

Vasan RS, Benjamin EJ. The Future of Cardiovascular Epidemiology. Circulation. 2016 Jun 21; 133(25):2626-33.View Related Profiles.

Benjamin, Emelia
Ramachandran, Vasan

PMID: 27324358; PMCID: PMC4974092; DOI: 10.1161/CIRCULATIONAHA.116.023528;

Januzzi JL, Lyass A, Liu Y, Gaggin H, Trebnick A, Maisel AS, D'Agostino RB, Wang TJ, Massaro J, Vasan RS. Circulating Proneurotensin Concentrations and Cardiovascular Disease Events in the Community: The Framingham Heart Study. Arterioscler Thromb Vasc Biol. 2016 Aug; 36(8):1692-7.View Related Profiles.

Massaro, Joseph
D'Agostino, Ralph
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PMID: 27312221; PMCID: PMC4965295; DOI: 10.1161/ATVBAHA.116.307847;

Waikar SS, Sabbisetti V, Ärnlöv J, Carlsson AC, Coresh J, Feldman HI, Foster MC, Fufaa GD, Helmersson-Karlqvist J, Hsu CY, Kimmel PL, Larsson A, Liu Y, Lind L, Liu KD, Mifflin TE, Nelson RG, Risérus U, Vasan RS, Xie D, Zhang X, Bonventre JV. Relationship of proximal tubular injury to chronic kidney disease as assessed by urinary kidney injury molecule-1 in five cohort studies. Nephrol Dial Transplant. 2016 Sep; 31(9):1460-70.View Related Profiles.

Waikar, Sushrut
Ramachandran, Vasan

PMID: 27270293; PMCID: PMC5009290; DOI: 10.1093/ndt/gfw203;

Santhanakrishnan R, Wang N, Larson MG, Magnani JW, McManus DD, Lubitz SA, Ellinor PT, Cheng S, Vasan RS, Lee DS, Wang TJ, Levy D, Benjamin EJ, Ho JE. Response to Letter Regarding Article, "Atrial Fibrillation Begets Heart Failure and Vice Versa: Temporal Associations and Differences in Preserved Versus Reduced Ejection Fraction". Circulation. 2016 Jun 7; 133(23):e692-3.View Related Profiles.

Levy, Daniel
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Larson, Martin
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PMID: 27267541; PMCID: PMC4902166; DOI: 10.1161/CIRCULATIONAHA.116.022835;

Tsao CW, Lyass A, Larson MG, Cheng S, Lam CS, Aragam JR, Benjamin EJ, Vasan RS. Prognosis of Adults With Borderline Left Ventricular Ejection Fraction. JACC Heart Fail. 2016 Jun; 4(6):502-10.View Related Profiles.

Benjamin, Emelia
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PMID: 27256754; PMCID: PMC4932891; DOI: 10.1016/j.jchf.2016.03.003;

Ho JE, Enserro D, Brouwers FP, Kizer JR, Shah SJ, Psaty BM, Bartz TM, Santhanakrishnan R, Lee DS, Chan C, Liu K, Blaha MJ, Hillege HL, van der Harst P, van Gilst WH, Kop WJ, Gansevoort RT, Vasan RS, Gardin JM, Levy D, Gottdiener JS, de Boer RA, Larson MG. Predicting Heart Failure With Preserved and Reduced Ejection Fraction: The International Collaboration on Heart Failure Subtypes. Circ Heart Fail. 2016 Jun; 9(6).View Related Profiles.

Levy, Daniel
Larson, Martin
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PMID: 27266854; PMCID: PMC4902276; DOI: 10.1161/CIRCHEARTFAILURE.115.003116;

Spartano NL, Lyass A, Larson MG, Lewis GD, Vasan RS. Submaximal Exercise Systolic Blood Pressure and Heart Rate at 20 Years of Follow-up: Correlates in the Framingham Heart Study. J Am Heart Assoc. 2016 May 27; 5(6).View Related Profiles.

Larson, Martin
Spartano, Nicole
Ramachandran, Vasan

PMID: 27233297; PMCID: PMC4937245; DOI: 10.1161/JAHA.115.002821;

Smith JG, Felix JF, Morrison AC, Kalogeropoulos A, Trompet S, Wilk JB, Gidlöf O, Wang X, Morley M, Mendelson M, Joehanes R, Ligthart S, Shan X, Bis JC, Wang YA, Sjögren M, Ngwa J, Brandimarto J, Stott DJ, Aguilar D, Rice KM, Sesso HD, Demissie S, Buckley BM, Taylor KD, Ford I, Yao C, Liu C, Sotoodehnia N, van der Harst P, Stricker BH, Kritchevsky SB, Liu Y, Gaziano JM, Hofman A, Moravec CS, Uitterlinden AG, Kellis M, van Meurs JB, Margulies KB, Dehghan A, Levy D, Olde B, Psaty BM, Cupples LA, Jukema JW, Djousse L, Franco OH, Boerwinkle E, Boyer LA, Newton-Cheh C, Butler J, Vasan RS, Cappola TP, Smith NL. Discovery of Genetic Variation on Chromosome 5q22 Associated with Mortality in Heart Failure. PLoS Genet. 2016 May; 12(5):e1006034.View Related Profiles.

Liu, Chunyu
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Demissie, Serkalem
Ramachandran, Vasan

PMID: 27149122; PMCID: PMC4858216; DOI: 10.1371/journal.pgen.1006034;

Lee JJ, Britton KA, Pedley A, Massaro JM, Speliotes EK, Murabito JM, Hoffmann U, Ingram C, Keaney JF, Vasan RS, Fox CS. Adipose Tissue Depots and Their Cross-Sectional Associations With Circulating Biomarkers of Metabolic Regulation. J Am Heart Assoc. 2016 May 04; 5(5).View Related Profiles.

Murabito, Joanne
Massaro, Joseph
Ramachandran, Vasan

PMID: 27146446; PMCID: PMC4889173; DOI: 10.1161/JAHA.115.002936;

Nayor M, Vasan RS. Recent Update to the US Cholesterol Treatment Guidelines: A Comparison With International Guidelines. Circulation. 2016 May 03; 133(18):1795-806.View Related Profiles.

Nayor, Matthew
Ramachandran, Vasan

PMID: 27143546; PMCID: PMC4857879; DOI: 10.1161/CIRCULATIONAHA.116.021407;

Kim EJ, Yin X, Fontes JD, Magnani JW, Lubitz SA, McManus DD, Seshadri S, Vasan RS, Ellinor PT, Larson MG, Benjamin EJ, Rienstra M. Atrial fibrillation without comorbidities: Prevalence, incidence and prognosis (from the Framingham Heart Study). Am Heart J. 2016 Jul; 177:138-44.View Related Profiles.

Benjamin, Emelia
Larson, Martin
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PMID: 27297859; PMCID: PMC4908973; DOI: 10.1016/j.ahj.2016.03.023;

Li W, Wilker EH, Dorans KS, Rice MB, Schwartz J, Coull BA, Koutrakis P, Gold DR, Keaney JF, Lin H, Vasan RS, Benjamin EJ, Mittleman MA. Short-Term Exposure to Air Pollution and Biomarkers of Oxidative Stress: The Framingham Heart Study. J Am Heart Assoc. 2016 Apr 28; 5(5).View Related Profiles.

Benjamin, Emelia
Lin, Honghuang
Ramachandran, Vasan

PMID: 27126478; PMCID: PMC4889166; DOI: 10.1161/JAHA.115.002742;

Niiranen TJ, Vasan RS. Epidemiology of cardiovascular disease: recent novel outlooks on risk factors and clinical approaches. Expert Rev Cardiovasc Ther. 2016 Jul; 14(7):855-69. PMID: 27057779; PMCID: PMC4961207; DOI: 10.1080/14779072.2016.1176528;

Pase MP, Beiser A, Enserro D, Xanthakis V, Aparicio H, Satizabal CL, Himali JJ, Kase CS, Vasan RS, DeCarli C, Seshadri S. Association of Ideal Cardiovascular Health With Vascular Brain Injury and Incident Dementia. Stroke. 2016 May; 47(5):1201-6.View Related Profiles.

Beiser, Alexa
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PMID: 27073239; PMCID: PMC5006676; DOI: 10.1161/STROKEAHA.115.012608;

Fox ER, Samdarshi TE, Musani SK, Pencina MJ, Sung JH, Bertoni AG, Xanthakis V, Balfour PC, Shreenivas SS, Covington C, Liebson PR, Sarpong DF, Butler KR, Mosley TH, Rosamond WD, Folsom AR, Herrington DM, Vasan RS, Taylor HA. Development and Validation of Risk Prediction Models for Cardiovascular Events in Black Adults: The Jackson Heart Study Cohort. JAMA Cardiol. 2016 04 01; 1(1):15-25.View Related Profiles.

Pencina, Michael
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PMID: 27437649; DOI: 10.1001/jamacardio.2015.0300;

Kaess BM, Rong J, Larson MG, Hamburg NM, Vita JA, Cheng S, Aragam J, Levy D, Benjamin EJ, Vasan RS, Mitchell GF. Relations of Central Hemodynamics and Aortic Stiffness with Left Ventricular Structure and Function: The Framingham Heart Study. J Am Heart Assoc. 2016 Mar 25; 5(3):e002693.View Related Profiles.

Kaess, Bernhard
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PMID: 27016574; PMCID: PMC4943246; DOI: 10.1161/JAHA.115.002693;

Santhanakrishnan R, Wang N, Larson MG, Magnani JM, Vasan RS, Wang TJ, Yap J, Feng L, Yap KB, Ong HY, Ng TP, Richards AM, Lam CS, Ho JE. Racial Differences in Electrocardiographic Characteristics and Prognostic Significance in Whites Versus Asians. J Am Heart Assoc. 2016 Mar 25; 5(3):e002956.View Related Profiles.

Larson, Martin
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PMID: 27016575; PMCID: PMC4943269; DOI: 10.1161/JAHA.115.002956;

Delling FN, Rong J, Larson MG, Lehman B, Fuller D, Osypiuk E, Stantchev P, Hackman B, Manning WJ, Benjamin EJ, Levine RA, Vasan RS. Evolution of Mitral Valve Prolapse: Insights From the Framingham Heart Study. Circulation. 2016 Apr 26; 133(17):1688-95.View Related Profiles.

Benjamin, Emelia
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PMID: 27006478; PMCID: PMC4856536; DOI: 10.1161/CIRCULATIONAHA.115.020621;

Romero JR, Preis SR, Beiser A, DeCarli C, D'Agostino RB, Wolf PA, Vasan RS, Polak JF, Seshadri S. Carotid Atherosclerosis and Cerebral Microbleeds: The Framingham Heart Study. J Am Heart Assoc. 2016 Mar 18; 5(3):e002377.View Related Profiles.

Beiser, Alexa
Romero, Jose
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PMID: 26994127; PMCID: PMC4943235; DOI: 10.1161/JAHA.115.002377;

Schnabel RB, Maas R, Wang N, Yin X, Larson MG, Levy D, Ellinor PT, Lubitz SA, McManus DD, Magnani JW, Atzler D, Böger RH, Schwedhelm E, Vasan RS, Benjamin EJ. Asymmetric dimethylarginine, related arginine derivatives, and incident atrial fibrillation. Am Heart J. 2016 Jun; 176:100-6.View Related Profiles.

Benjamin, Emelia
Larson, Martin
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PMID: 27264226; PMCID: PMC4899814; DOI: 10.1016/j.ahj.2016.03.007;

Maillard P, Mitchell GF, Himali JJ, Beiser A, Tsao CW, Pase MP, Satizabal CL, Vasan RS, Seshadri S, DeCarli C. Effects of Arterial Stiffness on Brain Integrity in Young Adults From the Framingham Heart Study. Stroke. 2016 Apr; 47(4):1030-6.View Related Profiles.

Beiser, Alexa
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PMID: 26965846; PMCID: PMC4811686; DOI: 10.1161/STROKEAHA.116.012949;

Dehghan A, Bis JC, White CC, Smith AV, Morrison AC, Cupples LA, Trompet S, Chasman DI, Lumley T, Völker U, Buckley BM, Ding J, Jensen MK, Folsom AR, Kritchevsky SB, Girman CJ, Ford I, Dörr M, Salomaa V, Uitterlinden AG, Eiriksdottir G, Vasan RS, Franceschini N, Carty CL, Virtamo J, Demissie S, Amouyel P, Arveiler D, Heckbert SR, Ferrières J, Ducimetière P, Smith NL, Wang YA, Siscovick DS, Rice KM, Wiklund PG, Taylor KD, Evans A, Kee F, Rotter JI, Karvanen J, Kuulasmaa K, Heiss G, Kraft P, Launer LJ, Hofman A, Markus MR, Rose LM, Silander K, Wagner P, Benjamin EJ, Lohman K, Stott DJ, Rivadeneira F, Harris TB, Levy D, Liu Y, Rimm EB, Jukema JW, Völzke H, Ridker PM, Blankenberg S, Franco OH, Gudnason V, Psaty BM, Boerwinkle E, O'Donnell CJ. Genome-Wide Association Study for Incident Myocardial Infarction and Coronary Heart Disease in Prospective Cohort Studies: The CHARGE Consortium. PLoS One. 2016; 11(3):e0144997.View Related Profiles.

O'Donnell, Christopher
Benjamin, Emelia
Cupples, L
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PMID: 26950853; PMCID: PMC4780701; DOI: 10.1371/journal.pone.0144997;

Foster MC, Coresh J, Hsu CY, Xie D, Levey AS, Nelson RG, Eckfeldt JH, Vasan RS, Kimmel PL, Schelling J, Simonson M, Sondheimer JH, Anderson AH, Akkina S, Feldman HI, Kusek JW, Ojo AO, Inker LA. Serum ß-Trace Protein and ß2-Microglobulin as Predictors of ESRD, Mortality, and Cardiovascular Disease in Adults With CKD in the Chronic Renal Insufficiency Cohort (CRIC) Study. Am J Kidney Dis. 2016 Jul; 68(1):68-76. PMID: 26948990; PMCID: PMC4921300; DOI: 10.1053/j.ajkd.2016.01.015;

Travison TG, O'Donnell CJ, Bhasin S, Massaro JM, Hoffmann U, Vasan RS, D'Agostino RB, Basaria S. Circulating Sex Steroids and Vascular Calcification in Community-Dwelling Men: The Framingham Heart Study. J Clin Endocrinol Metab. 2016 May; 101(5):2160-7.View Related Profiles.

O'Donnell, Christopher
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PMID: 26930184; PMCID: PMC4870846; DOI: 10.1210/jc.2015-4299;

Ljungman PL, Wilker EH, Rice MB, Austin E, Schwartz J, Gold DR, Koutrakis P, Benjamin EJ, Vita JA, Mitchell GF, Vasan RS, Hamburg NM, Mittleman MA. The Impact of Multipollutant Clusters on the Association Between Fine Particulate Air Pollution and Microvascular Function. Epidemiology. 2016 Mar; 27(2):194-201.View Related Profiles.

Benjamin, Emelia
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PMID: 26562062; DOI: 10.1097/EDE.0000000000000415;

Lee JJ, Pedley A, Hoffmann U, Massaro JM, Keaney JF, Vasan RS, Fox CS. Cross-Sectional Associations of Computed Tomography (CT)-Derived Adipose Tissue Density and Adipokines: The Framingham Heart Study. J Am Heart Assoc. 2016 Feb 29; 5(3):e002545.View Related Profiles.

Massaro, Joseph
Ramachandran, Vasan

PMID: 26927600; PMCID: PMC4943240; DOI: 10.1161/JAHA.115.002545;

Choi SH, Ruggiero D, Sorice R, Song C, Nutile T, Vernon Smith A, Concas MP, Traglia M, Barbieri C, Ndiaye NC, Stathopoulou MG, Lagou V, Maestrale GB, Sala C, Debette S, Kovacs P, Lind L, Lamont J, Fitzgerald P, Tönjes A, Gudnason V, Toniolo D, Pirastu M, Bellenguez C, Vasan RS, Ingelsson E, Leutenegger AL, Johnson AD, DeStefano AL, Visvikis-Siest S, Seshadri S, Ciullo M. Six Novel Loci Associated with Circulating VEGF Levels Identified by a Meta-analysis of Genome-Wide Association Studies. PLoS Genet. 2016 Feb; 12(2):e1005874.View Related Profiles.

DeStefano, Anita
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PMID: 26910538; PMCID: PMC4766012; DOI: 10.1371/journal.pgen.1005874;

Andersson C, Enserro D, Sullivan L, Wang TJ, Januzzi JL, Benjamin EJ, Vita JA, Hamburg NM, Larson MG, Mitchell GF, Vasan RS. Relations of circulating GDF-15, soluble ST2, and troponin-I concentrations with vascular function in the community: The Framingham Heart Study. Atherosclerosis. 2016 May; 248:245-51.View Related Profiles.

Benjamin, Emelia
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PMID: 26972631; PMCID: PMC5018232; DOI: 10.1016/j.atherosclerosis.2016.02.013;

Abulaban KM, Song H, Zhang X, Kimmel PL, Kusek JW, Nelson RG, Feldman HI, Vasan RS, Ying J, Mauer M, Nelsestuen GL, Bennett M, Brunner HI, Rovin BH. Predicting decline of kidney function in lupus nephritis using urine biomarkers. Lupus. 2016 Aug; 25(9):1012-8. PMID: 26873651; PMCID: PMC4945408; DOI: 10.1177/0961203316631629;

Willems SM, Cornes BK, Brody JA, Morrison AC, Lipovich L, Dauriz M, Chen Y, Liu CT, Rybin DV, Gibbs RA, Muzny D, Pankow JS, Psaty BM, Boerwinkle E, Rotter JI, Siscovick DS, Vasan RS, Kaplan RC, Isaacs A, Dupuis J, van Duijn CM, Meigs JB. Association of the IGF1 gene with fasting insulin levels. Eur J Hum Genet. 2016 Aug; 24(9):1337-43.View Related Profiles.

Liu, Ching-Ti
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PMID: 26860063; PMCID: PMC4989214; DOI: 10.1038/ejhg.2016.4;

Ho JE, Larson MG, Ghorbani A, Cheng S, Chen MH, Keyes M, Rhee EP, Clish CB, Vasan RS, Gerszten RE, Wang TJ. Metabolomic Profiles of Body Mass Index in the Framingham Heart Study Reveal Distinct Cardiometabolic Phenotypes. PLoS One. 2016; 11(2):e0148361.View Related Profiles.

Larson, Martin
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PMID: 26863521; PMCID: PMC4749349; DOI: 10.1371/journal.pone.0148361;

Spartano NL, Himali JJ, Beiser AS, Lewis GD, DeCarli C, Vasan RS, Seshadri S. Midlife exercise blood pressure, heart rate, and fitness relate to brain volume 2 decades later. Neurology. 2016 Apr 5; 86(14):1313-9.View Related Profiles.

Beiser, Alexa
Himali, Jayandra
Spartano, Nicole
Seshadri, Sudha
Ramachandran, Vasan

PMID: 26865519; PMCID: PMC4826343; DOI: 10.1212/WNL.0000000000002415;

Tofler GH, Massaro J, O'Donnell CJ, Wilson PW, Vasan RS, Sutherland PA, Meigs JB, Levy D, D'Agostino RB. Plasminogen activator inhibitor and the risk of cardiovascular disease: The Framingham Heart Study. Thromb Res. 2016 Apr; 140:30-5.View Related Profiles.

O'Donnell, Christopher
Massaro, Joseph
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 26896607; DOI: 10.1016/j.thromres.2016.02.002;

Pattaro C, Teumer A, Gorski M, Chu AY, Li M, Mijatovic V, Garnaas M, Tin A, Sorice R, Li Y, Taliun D, Olden M, Foster M, Yang Q, Chen MH, Pers TH, Johnson AD, Ko YA, Fuchsberger C, Tayo B, Nalls M, Feitosa MF, Isaacs A, Dehghan A, d'Adamo P, Adeyemo A, Dieffenbach AK, Zonderman AB, Nolte IM, van der Most PJ, Wright AF, Shuldiner AR, Morrison AC, Hofman A, Smith AV, Dreisbach AW, Franke A, Uitterlinden AG, Metspalu A, Tonjes A, Lupo A, Robino A, Johansson Å, Demirkan A, Kollerits B, Freedman BI, Ponte B, Oostra BA, Paulweber B, Krämer BK, Mitchell BD, Buckley BM, Peralta CA, Hayward C, Helmer C, Rotimi CN, Shaffer CM, Müller C, Sala C, van Duijn CM, Saint-Pierre A, Ackermann D, Shriner D, Ruggiero D, Toniolo D, Lu Y, Cusi D, Czamara D, Ellinghaus D, Siscovick DS, Ruderfer D, Gieger C, Grallert H, Rochtchina E, Atkinson EJ, Holliday EG, Boerwinkle E, Salvi E, Bottinger EP, Murgia F, Rivadeneira F, Ernst F, Kronenberg F, Hu FB, Navis GJ, Curhan GC, Ehret GB, Homuth G, Coassin S, Thun GA, Pistis G, Gambaro G, Malerba G, Montgomery GW, Eiriksdottir G, Jacobs G, Li G, Wichmann HE, Campbell H, Schmidt H, Wallaschofski H, Völzke H, Brenner H, Kroemer HK, Kramer H, Lin H, Leach IM, Ford I, Guessous I, Rudan I, Prokopenko I, Borecki I, Heid IM, Kolcic I, Persico I, Jukema JW, Wilson JF, Felix JF, Divers J, Lambert JC, Stafford JM, Gaspoz JM, Smith JA, Faul JD, Wang JJ, Ding J, Hirschhorn JN, Attia J, Whitfield JB, Chalmers J, Viikari J, Coresh J, Denny JC, Karjalainen J, Fernandes JK, Endlich K, Butterbach K, Keene KL, Lohman K, Portas L, Launer LJ, Lyytikäinen LP, Yengo L, Franke L, Ferrucci L, Rose LM, Kedenko L, Rao M, Struchalin M, Kleber ME, Cavalieri M, Haun M, Cornelis MC, Ciullo M, Pirastu M, de Andrade M, McEvoy MA, Woodward M, Adam M, Cocca M, Nauck M, Imboden M, Waldenberger M, Pruijm M, Metzger M, Stumvoll M, Evans MK, Sale MM, Kähönen M, Boban M, Bochud M, Rheinberger M, Verweij N, Bouatia-Naji N, Martin NG, Hastie N, Probst-Hensch N, Soranzo N, Devuyst O, Raitakari O, Gottesman O, Franco OH, Polasek O, Gasparini P, Munroe PB, Ridker PM, Mitchell P, Muntner P, Meisinger C, Smit JH, Kovacs P, Wild PS, Froguel P, Rettig R, Mägi R, Biffar R, Schmidt R, Middelberg RP, Carroll RJ, Penninx BW, Scott RJ, Katz R, Sedaghat S, Wild SH, Kardia SL, Ulivi S, Hwang SJ, Enroth S, Kloiber S, Trompet S, Stengel B, Hancock SJ, Turner ST, Rosas SE, Stracke S, Harris TB, Zeller T, Zemunik T, Lehtimäki T, Illig T, Aspelund T, Nikopensius T, Esko T, Tanaka T, Gyllensten U, Völker U, Emilsson V, Vitart V, Aalto V, Gudnason V, Chouraki V, Chen WM, Igl W, März W, Koenig W, Lieb W, Loos RJ, Liu Y, Snieder H, Pramstaller PP, Parsa A, O'Connell JR, Susztak K, Hamet P, Tremblay J, de Boer IH, Böger CA, Goessling W, Chasman DI, Köttgen A, Kao WH, Fox CS. Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function. Nat Commun. 2016; 7:10023.View Related Profiles.

Lin, Honghuang
Cupples, L
Yang, Qiong
Seshadri, Sudha
Ramachandran, Vasan

PMID: 26831199; PMCID: PMC4735748; DOI: 10.1038/ncomms10023;

Tsao CW, Himali JJ, Beiser AS, Larson MG, DeCarli C, Vasan RS, Mitchell GF, Seshadri S. Association of arterial stiffness with progression of subclinical brain and cognitive disease. Neurology. 2016 Feb 16; 86(7):619-26.View Related Profiles.

Beiser, Alexa
Himali, Jayandra
Larson, Martin
Seshadri, Sudha
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PMID: 26791155; PMCID: PMC4762417; DOI: 10.1212/WNL.0000000000002368;

Pase MP, Himali JJ, Mitchell GF, Beiser A, Maillard P, Tsao C, Larson MG, DeCarli C, Vasan RS, Seshadri S. Association of Aortic Stiffness With Cognition and Brain Aging in Young and Middle-Aged Adults: The Framingham Third Generation Cohort Study. Hypertension. 2016 Mar; 67(3):513-9.View Related Profiles.

Beiser, Alexa
Himali, Jayandra
Larson, Martin
Seshadri, Sudha
Ramachandran, Vasan

PMID: 26754644; PMCID: PMC4752398; DOI: 10.1161/HYPERTENSIONAHA.115.06610;

Santhanakrishnan R, Wang N, Larson MG, Magnani JW, McManus DD, Lubitz SA, Ellinor PT, Cheng S, Vasan RS, Lee DS, Wang TJ, Levy D, Benjamin EJ, Ho JE. Atrial Fibrillation Begets Heart Failure and Vice Versa: Temporal Associations and Differences in Preserved Versus Reduced Ejection Fraction. Circulation. 2016 Feb 2; 133(5):484-92.View Related Profiles.

Levy, Daniel
Benjamin, Emelia
Magnani, Jared
Larson, Martin
Ramachandran, Vasan

PMID: 26746177; PMCID: PMC4738087; DOI: 10.1161/CIRCULATIONAHA.115.018614;

Karakis I, Pase MP, Beiser A, Booth SL, Jacques PF, Rogers G, DeCarli C, Vasan RS, Wang TJ, Himali JJ, Annweiler C, Seshadri S. Association of Serum Vitamin D with the Risk of Incident Dementia and Subclinical Indices of Brain Aging: The Framingham Heart Study. J Alzheimers Dis. 2016; 51(2):451-61.View Related Profiles.

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Himali, Jayandra
Seshadri, Sudha
Ramachandran, Vasan

PMID: 26890771; PMCID: PMC4911705; DOI: 10.3233/JAD-150991;

Nayor M, Wang N, Larson MG, Vasan RS, Levy D, Ho JE. Circulating Galectin-3 Is Associated With Cardiometabolic Disease in the Community. J Am Heart Assoc. 2015 Dec 31; 5(1).View Related Profiles.

Larson, Martin
Nayor, Matthew
Ramachandran, Vasan

PMID: 26722123; PMCID: PMC4859357; DOI: 10.1161/JAHA.115.002347;

Nayor M, Enserro DM, Vasan RS, Xanthakis V. Cardiovascular Health Status and Incidence of Heart Failure in the Framingham Offspring Study. Circ Heart Fail. 2016 Jan; 9(1):e002416.View Related Profiles.

Nayor, Matthew
Xanthakis, Vanessa
Ramachandran, Vasan

PMID: 26699391; PMCID: PMC4692176; DOI: 10.1161/CIRCHEARTFAILURE.115.002416;

Nayor M, Enserro DM, Beiser AS, Cheng S, DeCarli C, Vasan RS, Seshadri S. Association of Exhaled Carbon Monoxide With Stroke Incidence and Subclinical Vascular Brain Injury: Framingham Heart Study. Stroke. 2016 Feb; 47(2):383-9.View Related Profiles.

Beiser, Alexa
Nayor, Matthew
Seshadri, Sudha
Ramachandran, Vasan

PMID: 26696648; PMCID: PMC4729607; DOI: 10.1161/STROKEAHA.115.010405;

Tsao CW, Vasan RS. The Framingham Heart Study: past, present and future. Int J Epidemiol. 2015 Dec; 44(6):1763-6. PMID: 26705413; DOI: 10.1093/ije/dyv336;

Tsao CW, Vasan RS. Cohort Profile: The Framingham Heart Study (FHS): overview of milestones in cardiovascular epidemiology. Int J Epidemiol. 2015 Dec; 44(6):1800-13. PMID: 26705418; DOI: 10.1093/ije/dyv337;

Zachariah JP, Hwang S, Hamburg NM, Benjamin EJ, Larson MG, Levy D, Vita JA, Sullivan LM, Mitchell GF, Vasan RS. Circulating Adipokines and Vascular Function: Cross-Sectional Associations in a Community-Based Cohort. Hypertension. 2016 Feb; 67(2):294-300.View Related Profiles.

Levy, Daniel
Benjamin, Emelia
Sullivan, Lisa
Larson, Martin
Hamburg, Naomi
Ramachandran, Vasan

PMID: 26628673; PMCID: PMC4845672; DOI: 10.1161/HYPERTENSIONAHA.115.05949;

Chami HA, Vasan RS, Larson MG, Benjamin EJ, Mitchell GF, Gottlieb DJ. The association between sleep-disordered breathing and aortic stiffness in a community cohort. Sleep Med. 2016 Mar; 19:69-74.View Related Profiles.

Benjamin, Emelia
Larson, Martin
Ramachandran, Vasan

PMID: 27198950; PMCID: PMC4875564; DOI: 10.1016/j.sleep.2015.11.009;

Tsao CW, Lyass A, Larson MG, Levy D, Hamburg NM, Vita JA, Benjamin EJ, Mitchell GF, Vasan RS. Relation of Central Arterial Stiffness to Incident Heart Failure in the Community. J Am Heart Assoc. 2015 Nov; 4(11).View Related Profiles.

Benjamin, Emelia
Larson, Martin
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Ramachandran, Vasan

PMID: 26597152; PMCID: PMC4845230; DOI: 10.1161/JAHA.115.002189;

Lieb W, Enserro DM, Sullivan LM, Vasan RS. Residual Cardiovascular Risk in Individuals on Blood Pressure-Lowering Treatment. J Am Heart Assoc. 2015 Nov; 4(11).View Related Profiles.

Sullivan, Lisa
Ramachandran, Vasan

PMID: 26588944; PMCID: PMC4845218; DOI: 10.1161/JAHA.115.002155;

Pase MP, Beiser A, Aparicio H, DeCarli C, Vasan RS, Murabito J, Seshadri S. Interarm differences in systolic blood pressure and the risk of dementia and subclinical brain injury. Alzheimers Dement. 2016 Apr; 12(4):438-45.View Related Profiles.

Beiser, Alexa
Aparicio, Hugo
Murabito, Joanne
Seshadri, Sudha
Ramachandran, Vasan

PMID: 26542262; PMCID: PMC4841714; DOI: 10.1016/j.jalz.2015.09.006;

Bis JC, Sitlani C, Irvin R, Avery CL, Smith AV, Sun F, Evans DS, Musani SK, Li X, Trompet S, Krijthe BP, Harris TB, Quibrera PM, Brody JA, Demissie S, Davis BR, Wiggins KL, Tranah GJ, Lange LA, Sotoodehnia N, Stott DJ, Franco OH, Launer LJ, Stürmer T, Taylor KD, Cupples LA, Eckfeldt JH, Smith NL, Liu Y, Wilson JG, Heckbert SR, Buckley BM, Ikram MA, Boerwinkle E, Chen YD, de Craen AJ, Uitterlinden AG, Rotter JI, Ford I, Hofman A, Sattar N, Slagboom PE, Westendorp RG, Gudnason V, Vasan RS, Lumley T, Cummings SR, Taylor HA, Post W, Jukema JW, Stricker BH, Whitsel EA, Psaty BM, Arnett D. Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium. PLoS One. 2015; 10(10):e0140496.View Related Profiles.

Sun, Fangui
Cupples, L
Demissie, Serkalem
Ramachandran, Vasan

PMID: 26516778; PMCID: PMC4627813; DOI: 10.1371/journal.pone.0140496;

Cheng S, McCabe EL, Larson MG, Merz AA, Osypiuk E, Lehman BT, Stantchev P, Aragam J, Solomon SD, Benjamin EJ, Vasan RS. Distinct Aspects of Left Ventricular Mechanical Function Are Differentially Associated With Cardiovascular Outcomes and All-Cause Mortality in the Community. J Am Heart Assoc. 2015 Oct; 4(10):e002071.View Related Profiles.

Benjamin, Emelia
Osypiuk, Ewa
Aragam, Jayashri
Larson, Martin
Ramachandran, Vasan

PMID: 26508740; PMCID: PMC4845131; DOI: 10.1161/JAHA.115.002071;

Rebholz CM, Grams ME, Lutsey PL, Hoofnagle AN, Misialek JR, Inker LA, Levey AS, Selvin E, Hsu CY, Kimmel PL, Vasan RS, Eckfeldt JH, Coresh J. Biomarkers of Vitamin D Status and Risk of ESRD. Am J Kidney Dis. 2016 Feb; 67(2):235-42. PMID: 26475393; PMCID: PMC4724452; DOI: 10.1053/j.ajkd.2015.08.026;

Delling FN, Rong J, Larson MG, Lehman B, Osypiuk E, Stantchev P, Slaugenhaupt SA, Benjamin EJ, Levine RA, Vasan RS. Response to Letter Regarding Article, "Familial Clustering of Mitral Valve Prolapse in the Community". Circulation. 2015 Oct 6; 132(14):e187-8.View Related Profiles.

Benjamin, Emelia
Osypiuk, Ewa
Larson, Martin
Ramachandran, Vasan

PMID: 26438779; PMCID: PMC4620666; DOI: 10.1161/CIRCULATIONAHA.115.016788;

Andersson C, Vasan RS. Lipophilic Statins and Aldosterone Secretion: A Bridge Too Far? Circulation. 2015 Nov 10; 132(19):1783-5. PMID: 26432672; DOI: 10.1161/CIRCULATIONAHA.115.019130;

Andersson C, Lyass A, Larson MG, Robins SJ, Vasan RS. Low-density-lipoprotein cholesterol concentrations and risk of incident diabetes: epidemiological and genetic insights from the Framingham Heart Study. Diabetologia. 2015 Dec; 58(12):2774-80.View Related Profiles.

Larson, Martin
Robins, Sander
Ramachandran, Vasan

PMID: 26409460; PMCID: PMC4631796; DOI: 10.1007/s00125-015-3762-x;

Foster MC, Coresh J, Bonventre JV, Sabbisetti VS, Waikar SS, Mifflin TE, Nelson RG, Grams M, Feldman HI, Vasan RS, Kimmel PL, Hsu CY, Liu KD. Urinary Biomarkers and Risk of ESRD in the Atherosclerosis Risk in Communities Study. Clin J Am Soc Nephrol. 2015 Nov 6; 10(11):1956-63.View Related Profiles.

Waikar, Sushrut
Ramachandran, Vasan

PMID: 26350438; PMCID: PMC4633784; DOI: 10.2215/CJN.02590315;

Saber H, Himali JJ, Shoamanesh A, Beiser A, Pikula A, Harris TB, Roubenoff R, Romero JR, Kase CS, Vasan RS, Seshadri S. Serum Leptin Levels and the Risk of Stroke: The Framingham Study. Stroke. 2015 Oct; 46(10):2881-5.View Related Profiles.

Beiser, Alexa
Shoamanesh, Ashkan
Kase, Carlos
Himali, Jayandra
Romero, Jose
Seshadri, Sudha
Ramachandran, Vasan

PMID: 26337973; PMCID: PMC4589501; DOI: 10.1161/STROKEAHA.115.009463;

Nayor M, Vasan RS. Preventing heart failure: the role of physical activity. Curr Opin Cardiol. 2015 Sep; 30(5):543-50.View Related Profiles.

Nayor, Matthew
Ramachandran, Vasan

PMID: 26154074; PMCID: PMC4615715; DOI: 10.1097/HCO.0000000000000206;

Dina C, Bouatia-Naji N, Tucker N, Delling FN, Toomer K, Durst R, Perrocheau M, Fernandez-Friera L, Solis J, Le Tourneau T, Chen MH, Probst V, Bosse Y, Pibarot P, Zelenika D, Lathrop M, Hercberg S, Roussel R, Benjamin EJ, Bonnet F, Lo SH, Dolmatova E, Simonet F, Lecointe S, Kyndt F, Redon R, Le Marec H, Froguel P, Ellinor PT, Vasan RS, Bruneval P, Markwald RR, Norris RA, Milan DJ, Slaugenhaupt SA, Levine RA, Schott JJ, Hagege AA, Jeunemaitre X. Genetic association analyses highlight biological pathways underlying mitral valve prolapse. Nat Genet. 2015 Oct; 47(10):1206-11.View Related Profiles.

Benjamin, Emelia
Ramachandran, Vasan

PMID: 26301497; PMCID: PMC4773907; DOI: 10.1038/ng.3383;

Kenchaiah S, Vasan RS. Heart Failure in Women--Insights from the Framingham Heart Study. Cardiovasc Drugs Ther. 2015 Aug; 29(4):377-90.View Related Profiles.

Kenchaiah, Satish
Ramachandran, Vasan

PMID: 26245740; DOI: 10.1007/s10557-015-6599-0;

Andersson C, Preis SR, Beiser A, DeCarli C, Wollert KC, Wang TJ, Januzzi JL, Vasan RS, Seshadri S. Associations of Circulating Growth Differentiation Factor-15 and ST2 Concentrations With Subclinical Vascular Brain Injury and Incident Stroke. Stroke. 2015 Sep; 46(9):2568-75.View Related Profiles.

Beiser, Alexa
Preis, Sarah
Seshadri, Sudha
Ramachandran, Vasan

PMID: 26219649; PMCID: PMC4550531; DOI: 10.1161/STROKEAHA.115.009026;

Rahman F, Wang N, Yin X, Ellinor PT, Lubitz SA, LeLorier PA, McManus DD, Sullivan LM, Seshadri S, Vasan RS, Benjamin EJ, Magnani JW. Atrial flutter: Clinical risk factors and adverse outcomes in the Framingham Heart Study. Heart Rhythm. 2016 Jan; 13(1):233-40.View Related Profiles.

Benjamin, Emelia
Rahman, Faisal
Magnani, Jared
Sullivan, Lisa
Seshadri, Sudha
Ramachandran, Vasan
Yin, Xiaoyan

PMID: 26226213; PMCID: PMC4698205; DOI: 10.1016/j.hrthm.2015.07.031;

Jansen H, Loley C, Lieb W, Pencina MJ, Nelson CP, Kathiresan S, Peloso GM, Voight BF, Reilly MP, Assimes TL, Boerwinkle E, Hengstenberg C, Laaksonen R, McPherson R, Roberts R, Thorsteinsdottir U, Peters A, Gieger C, Rawal R, Thompson JR, König IR, Vasan RS, Erdmann J, Samani NJ, Schunkert H. Genetic variants primarily associated with type 2 diabetes are related to coronary artery disease risk. Atherosclerosis. 2015 Aug; 241(2):419-26.View Related Profiles.

Peloso, Gina
Pencina, Michael
Ramachandran, Vasan

PMID: 26074316; PMCID: PMC4536952; DOI: 10.1016/j.atherosclerosis.2015.05.033;

Cheng S, Larson MG, McCabe EL, Murabito JM, Rhee EP, Ho JE, Jacques PF, Ghorbani A, Magnusson M, Souza AL, Deik AA, Pierce KA, Bullock K, O'Donnell CJ, Melander O, Clish CB, Vasan RS, Gerszten RE, Wang TJ. Erratum: Distinct metabolomic signatures are associated with longevity in humans. Nat Commun. 2015; 6:7317.View Related Profiles.

O'Donnell, Christopher
Murabito, Joanne
Larson, Martin
Ramachandran, Vasan

PMID: 25993905; DOI: 10.1038/ncomms8317;

Long MT, Pedley A, Massaro JM, Hoffmann U, Esliger DW, Vasan RS, Fox CS, Murabito JM. Hepatic steatosis is associated with lower levels of physical activity measured via accelerometry. Obesity (Silver Spring). 2015 Jun; 23(6):1259-66.View Related Profiles.

Murabito, Joanne
Massaro, Joseph
Long, Michelle
Ramachandran, Vasan

PMID: 25959049; PMCID: PMC4446168; DOI: 10.1002/oby.21058;

Schnabel RB, Yin X, Gona P, Larson MG, Beiser AS, McManus DD, Newton-Cheh C, Lubitz SA, Magnani JW, Ellinor PT, Seshadri S, Wolf PA, Vasan RS, Benjamin EJ, Levy D. 50 year trends in atrial fibrillation prevalence, incidence, risk factors, and mortality in the Framingham Heart Study: a cohort study. Lancet. 2015 Jul 11; 386(9989):154-62.View Related Profiles.

Beiser, Alexa
Benjamin, Emelia
Magnani, Jared
Larson, Martin
Wolf, Philip
Seshadri, Sudha
Ramachandran, Vasan

PMID: 25960110; PMCID: PMC4553037; DOI: 10.1016/S0140-6736(14)61774-8;

Sauder KA, Proctor DN, Chow M, Troy LM, Wang N, Vita JA, Vasan RS, Mitchell GF, Jacques PF, Hamburg NM, West SG. Endothelial function, arterial stiffness and adherence to the 2010 Dietary Guidelines for Americans: a cross-sectional analysis. Br J Nutr. 2015 Jun 14; 113(11):1773-81.View Related Profiles.

Hamburg, Naomi
Ramachandran, Vasan

PMID: 25885520; PMCID: PMC4466070; DOI: 10.1017/S0007114515000859;

Andersson C, Enserro D, Larson MG, Xanthakis V, Vasan RS. Implications of the US cholesterol guidelines on eligibility for statin therapy in the community: comparison of observed and predicted risks in the Framingham Heart Study Offspring Cohort. J Am Heart Assoc. 2015 Apr; 4(4).View Related Profiles.

Larson, Martin
Xanthakis, Vanessa
Ramachandran, Vasan

PMID: 25888372; PMCID: PMC4579932; DOI: 10.1161/JAHA.115.001888;

Huan T, Meng Q, Saleh MA, Norlander AE, Joehanes R, Zhu J, Chen BH, Zhang B, Johnson AD, Ying S, Courchesne P, Raghavachari N, Wang R, Liu P, O'Donnell CJ, Vasan R, Munson PJ, Madhur MS, Harrison DG, Yang X, Levy D. Integrative network analysis reveals molecular mechanisms of blood pressure regulation. Mol Syst Biol. 2015 Jan; 11(1):799.View Related Profiles.

O'Donnell, Christopher
Ramachandran, Vasan

PMID: 25882670; PMCID: PMC4422556; DOI: 10.15252/msb.20145399;

Cheng S, Larson MG, McCabe EL, Murabito JM, Rhee EP, Ho JE, Jacques PF, Ghorbani A, Magnusson M, Souza AL, Deik AA, Pierce KA, Bullock K, O'Donnell CJ, Melander O, Clish CB, Vasan RS, Gerszten RE, Wang TJ. Distinct metabolomic signatures are associated with longevity in humans. Nat Commun. 2015; 6:6791.View Related Profiles.

O'Donnell, Christopher
Ho, Jennifer
Murabito, Joanne
Larson, Martin
Ramachandran, Vasan

PMID: 25864806; PMCID: PMC4396657; DOI: 10.1038/ncomms7791;

Fontes JD, Rahman F, Lacey S, Larson MG, Vasan RS, Benjamin EJ, Harris WS, Robins SJ. Red blood cell fatty acids and biomarkers of inflammation: a cross-sectional study in a community-based cohort. Atherosclerosis. 2015 Jun; 240(2):431-6.View Related Profiles.

Benjamin, Emelia
Rahman, Faisal
Larson, Martin
Robins, Sander
Ramachandran, Vasan

PMID: 25897795; PMCID: PMC4511480; DOI: 10.1016/j.atherosclerosis.2015.03.043;

Andersson C, Lyass A, Larson MG, Spartano NL, Vita JA, Benjamin EJ, Murabito JM, Esliger DW, Blease SJ, Hamburg NM, Mitchell GF, Vasan RS. Physical activity measured by accelerometry and its associations with cardiac structure and vascular function in young and middle-aged adults. J Am Heart Assoc. 2015 Mar; 4(3):e001528.View Related Profiles.

Benjamin, Emelia
Murabito, Joanne
Vita, Joseph
Larson, Martin
Hamburg, Naomi
Spartano, Nicole
Ramachandran, Vasan

PMID: 25792127; PMCID: PMC4392434; DOI: 10.1161/JAHA.114.001528;

Huan T, Esko T, Peters MJ, Pilling LC, Schramm K, Schurmann C, Chen BH, Liu C, Joehanes R, Johnson AD, Yao C, Ying SX, Courchesne P, Milani L, Raghavachari N, Wang R, Liu P, Reinmaa E, Dehghan A, Hofman A, Uitterlinden AG, Hernandez DG, Bandinelli S, Singleton A, Melzer D, Metspalu A, Carstensen M, Grallert H, Herder C, Meitinger T, Peters A, Roden M, Waldenberger M, Dörr M, Felix SB, Zeller T, Vasan R, O'Donnell CJ, Munson PJ, Yang X, Prokisch H, Völker U, van Meurs JB, Ferrucci L, Levy D. A meta-analysis of gene expression signatures of blood pressure and hypertension. PLoS Genet. 2015 Mar; 11(3):e1005035.View Related Profiles.

O'Donnell, Christopher
Liu, Chunyu
Ramachandran, Vasan

PMID: 25785607; PMCID: PMC4365001; DOI: 10.1371/journal.pgen.1005035;

Lubitz SA, Yin X, Rienstra M, Schnabel RB, Walkey AJ, Magnani JW, Rahman F, McManus DD, Tadros TM, Levy D, Vasan RS, Larson MG, Ellinor PT, Benjamin EJ. Long-term outcomes of secondary atrial fibrillation in the community: the Framingham Heart Study. Circulation. 2015 May 12; 131(19):1648-55.View Related Profiles.

Walkey, Allan
Levy, Daniel
Benjamin, Emelia
Rahman, Faisal
Magnani, Jared
Larson, Martin
Ramachandran, Vasan
Yin, Xiaoyan

PMID: 25769640; PMCID: PMC4430386; DOI: 10.1161/CIRCULATIONAHA.114.014058;

Foster MC, Inker LA, Hsu CY, Eckfeldt JH, Levey AS, Pavkov ME, Myers BD, Bennett PH, Kimmel PL, Vasan RS, Coresh J, Nelson RG. Filtration markers as predictors of ESRD and mortality in Southwestern American Indians with type 2 diabetes. Am J Kidney Dis. 2015 Jul; 66(1):75-83. PMID: 25773485; PMCID: PMC4485524; DOI: 10.1053/j.ajkd.2015.01.013;

Xanthakis V, Sung JH, Samdarshi TE, Hill AN, Musani SK, Sims M, Ghraibeh KA, Liebson PR, Taylor HA, Vasan RS, Fox ER. Relations between subclinical disease markers and type 2 diabetes, metabolic syndrome, and incident cardiovascular disease: the Jackson Heart Study. Diabetes Care. 2015 Jun; 38(6):1082-8.View Related Profiles.

Xanthakis, Vanessa
Ramachandran, Vasan

PMID: 25765357; PMCID: PMC4439537; DOI: 10.2337/dc14-2460;

Kaess BM, Preis SR, Lieb W, Beiser AS, Yang Q, Chen TC, Hengstenberg C, Erdmann J, Schunkert H, Seshadri S, Vasan RS, Assimes TL, Deloukas P, Holm H, Kathiresan S, König IR, McPherson R, Reilly MP, Roberts R, Samani NJ, Stewart AF. Circulating brain-derived neurotrophic factor concentrations and the risk of cardiovascular disease in the community. J Am Heart Assoc. 2015 Mar; 4(3):e001544.View Related Profiles.

Beiser, Alexa
Kaess, Bernhard
Yang, Qiong
Preis, Sarah
Seshadri, Sudha
Chen, Tai
Ramachandran, Vasan

PMID: 25762803; PMCID: PMC4392437; DOI: 10.1161/JAHA.114.001544;

Long MT, Wang N, Larson MG, Mitchell GF, Palmisano J, Vasan RS, Hoffmann U, Speliotes EK, Vita JA, Benjamin EJ, Fox CS, Hamburg NM. Nonalcoholic fatty liver disease and vascular function: cross-sectional analysis in the Framingham heart study. Arterioscler Thromb Vasc Biol. 2015 May; 35(5):1284-91.View Related Profiles.

Benjamin, Emelia
Vita, Joseph
Larson, Martin
Long, Michelle
Hamburg, Naomi
Ramachandran, Vasan

PMID: 25745056; PMCID: PMC4520415; DOI: 10.1161/ATVBAHA.114.305200;

Hsu CY, Ballard S, Batlle D, Bonventre JV, Böttinger EP, Feldman HI, Klein JB, Coresh J, Eckfeldt JH, Inker LA, Kimmel PL, Kusek JW, Liu KD, Mauer M, Mifflin TE, Molitch ME, Nelsestuen GL, Rebholz CM, Rovin BH, Sabbisetti VS, Van Eyk JE, Vasan RS, Waikar SS, Whitehead KM, Nelson RG. Cross-Disciplinary Biomarkers Research: Lessons Learned by the CKD Biomarkers Consortium. Clin J Am Soc Nephrol. 2015 May 7; 10(5):894-902.View Related Profiles.

Waikar, Sushrut
Ramachandran, Vasan

PMID: 25739849; PMCID: PMC4422251; DOI: 10.2215/CJN.11541114;

Vasan RS, Folsom AR. Invited commentary: future of population studies--defining research priorities and processes. Am J Epidemiol. 2015 Mar 15; 181(6):369-71. PMID: 25743322; PMCID: PMC4380021; DOI: 10.1093/aje/kwv012;

Murabito JM, Pedley A, Massaro JM, Vasan RS, Esliger D, Blease SJ, Hoffman U, Fox CS. Moderate-to-vigorous physical activity with accelerometry is associated with visceral adipose tissue in adults. J Am Heart Assoc. 2015 Mar; 4(3):e001379.View Related Profiles.

Murabito, Joanne
Massaro, Joseph
Ramachandran, Vasan

PMID: 25736442; PMCID: PMC4392428; DOI: 10.1161/JAHA.114.001379;

Shungin D, Winkler TW, Croteau-Chonka DC, Ferreira T, Locke AE, Mägi R, Strawbridge RJ, Pers TH, Fischer K, Justice AE, Workalemahu T, Wu JM, Buchkovich ML, Heard-Costa NL, Roman TS, Drong AW, Song C, Gustafsson S, Day FR, Esko T, Fall T, Kutalik Z, Luan J, Randall JC, Scherag A, Vedantam S, Wood AR, Chen J, Fehrmann R, Karjalainen J, Kahali B, Liu CT, Schmidt EM, Absher D, Amin N, Anderson D, Beekman M, Bragg-Gresham JL, Buyske S, Demirkan A, Ehret GB, Feitosa MF, Goel A, Jackson AU, Johnson T, Kleber ME, Kristiansson K, Mangino M, Mateo Leach I, Medina-Gomez C, Palmer CD, Pasko D, Pechlivanis S, Peters MJ, Prokopenko I, Stancáková A, Ju Sung Y, Tanaka T, Teumer A, Van Vliet-Ostaptchouk JV, Yengo L, Zhang W, Albrecht E, Ärnlöv J, Arscott GM, Bandinelli S, Barrett A, Bellis C, Bennett AJ, Berne C, Blüher M, Böhringer S, Bonnet F, Böttcher Y, Bruinenberg M, Carba DB, Caspersen IH, Clarke R, Daw EW, Deelen J, Deelman E, Delgado G, Doney AS, Eklund N, Erdos MR, Estrada K, Eury E, Friedrich N, Garcia ME, Giedraitis V, Gigante B, Go AS, Golay A, Grallert H, Grammer TB, Gräßler J, Grewal J, Groves CJ, Haller T, Hallmans G, Hartman CA, Hassinen M, Hayward C, Heikkilä K, Herzig KH, Helmer Q, Hillege HL, Holmen O, Hunt SC, Isaacs A, Ittermann T, James AL, Johansson I, Juliusdottir T, Kalafati IP, Kinnunen L, Koenig W, Kooner IK, Kratzer W, Lamina C, Leander K, Lee NR, Lichtner P, Lind L, Lindström J, Lobbens S, Lorentzon M, Mach F, Magnusson PK, Mahajan A, McArdle WL, Menni C, Merger S, Mihailov E, Milani L, Mills R, Moayyeri A, Monda KL, Mooijaart SP, Mühleisen TW, Mulas A, Müller G, Müller-Nurasyid M, Nagaraja R, Nalls MA, Narisu N, Glorioso N, Nolte IM, Olden M, Rayner NW, Renstrom F, Ried JS, Robertson NR, Rose LM, Sanna S, Scharnagl H, Scholtens S, Sennblad B, Seufferlein T, Sitlani CM, Vernon Smith A, Stirrups K, Stringham HM, Sundström J, Swertz MA, Swift AJ, Syvänen AC, Tayo BO, Thorand B, Thorleifsson G, Tomaschitz A, Troffa C, van Oort FV, Verweij N, Vonk JM, Waite LL, Wennauer R, Wilsgaard T, Wojczynski MK, Wong A, Zhang Q, Hua Zhao J, Brennan EP, Choi M, Eriksson P, Folkersen L, Franco-Cereceda A, Gharavi AG, Hedman ÅK, Hivert MF, Huang J, Kanoni S, Karpe F, Keildson S, Kiryluk K, Liang L, Lifton RP, Ma B, McKnight AJ, McPherson R, Metspalu A, Min JL, Moffatt MF, Montgomery GW, Murabito JM, Nicholson G, Nyholt DR, Olsson C, Perry JR, Reinmaa E, Salem RM, Sandholm N, Schadt EE, Scott RA, Stolk L, Vallejo EE, Westra HJ, Zondervan KT, Amouyel P, Arveiler D, Bakker SJ, Beilby J, Bergman RN, Blangero J, Brown MJ, Burnier M, Campbell H, Chakravarti A, Chines PS, Claudi-Boehm S, Collins FS, Crawford DC, Danesh J, de Faire U, de Geus EJ, Dörr M, Erbel R, Eriksson JG, Farrall M, Ferrannini E, Ferrières J, Forouhi NG, Forrester T, Franco OH, Gansevoort RT, Gieger C, Gudnason V, Haiman CA, Harris TB, Hattersley AT, Heliövaara M, Hicks AA, Hingorani AD, Hoffmann W, Hofman A, Homuth G, Humphries SE, Hyppönen E, Illig T, Jarvelin MR, Johansen B, Jousilahti P, Jula AM, Kaprio J, Kee F, Keinanen-Kiukaanniemi SM, Kooner JS, Kooperberg C, Kovacs P, Kraja AT, Kumari M, Kuulasmaa K, Kuusisto J, Lakka TA, Langenberg C, Le Marchand L, Lehtimäki T, Lyssenko V, Männistö S, Marette A, Matise TC, McKenzie CA, McKnight B, Musk AW, Möhlenkamp S, Morris AD, Nelis M, Ohlsson C, Oldehinkel AJ, Ong KK, Palmer LJ, Penninx BW, Peters A, Pramstaller PP, Raitakari OT, Rankinen T, Rao DC, Rice TK, Ridker PM, Ritchie MD, Rudan I, Salomaa V, Samani NJ, Saramies J, Sarzynski MA, Schwarz PE, Shuldiner AR, Staessen JA, Steinthorsdottir V, Stolk RP, Strauch K, Tönjes A, Tremblay A, Tremoli E, Vohl MC, Völker U, Vollenweider P, Wilson JF, Witteman JC, Adair LS, Bochud M, Boehm BO, Bornstein SR, Bouchard C, Cauchi S, Caulfield MJ, Chambers JC, Chasman DI, Cooper RS, Dedoussis G, Ferrucci L, Froguel P, Grabe HJ, Hamsten A, Hui J, Hveem K, Jöckel KH, Kivimaki M, Kuh D, Laakso M, Liu Y, März W, Munroe PB, Njølstad I, Oostra BA, Palmer CN, Pedersen NL, Perola M, et al. NeView Related Profiles.

Liu, Ching-Ti
Murabito, Joanne
Cupples, L
Heard-Costa, Nancy
Ramachandran, Vasan

PMID: 25673412; PMCID: PMC4338562; DOI: 10.1038/nature14132;

Locke AE, Kahali B, Berndt SI, Justice AE, Pers TH, Day FR, Powell C, Vedantam S, Buchkovich ML, Yang J, Croteau-Chonka DC, Esko T, Fall T, Ferreira T, Gustafsson S, Kutalik Z, Luan J, Mägi R, Randall JC, Winkler TW, Wood AR, Workalemahu T, Faul JD, Smith JA, Hua Zhao J, Zhao W, Chen J, Fehrmann R, Hedman ÅK, Karjalainen J, Schmidt EM, Absher D, Amin N, Anderson D, Beekman M, Bolton JL, Bragg-Gresham JL, Buyske S, Demirkan A, Deng G, Ehret GB, Feenstra B, Feitosa MF, Fischer K, Goel A, Gong J, Jackson AU, Kanoni S, Kleber ME, Kristiansson K, Lim U, Lotay V, Mangino M, Mateo Leach I, Medina-Gomez C, Medland SE, Nalls MA, Palmer CD, Pasko D, Pechlivanis S, Peters MJ, Prokopenko I, Shungin D, Stancáková A, Strawbridge RJ, Ju Sung Y, Tanaka T, Teumer A, Trompet S, van der Laan SW, van Setten J, Van Vliet-Ostaptchouk JV, Wang Z, Yengo L, Zhang W, Isaacs A, Albrecht E, Ärnlöv J, Arscott GM, Attwood AP, Bandinelli S, Barrett A, Bas IN, Bellis C, Bennett AJ, Berne C, Blagieva R, Blüher M, Böhringer S, Bonnycastle LL, Böttcher Y, Boyd HA, Bruinenberg M, Caspersen IH, Ida Chen YD, Clarke R, Daw EW, de Craen AJ, Delgado G, Dimitriou M, Doney AS, Eklund N, Estrada K, Eury E, Folkersen L, Fraser RM, Garcia ME, Geller F, Giedraitis V, Gigante B, Go AS, Golay A, Goodall AH, Gordon SD, Gorski M, Grabe HJ, Grallert H, Grammer TB, Gräßler J, Grönberg H, Groves CJ, Gusto G, Haessler J, Hall P, Haller T, Hallmans G, Hartman CA, Hassinen M, Hayward C, Heard-Costa NL, Helmer Q, Hengstenberg C, Holmen O, Hottenga JJ, James AL, Jeff JM, Johansson Å, Jolley J, Juliusdottir T, Kinnunen L, Koenig W, Koskenvuo M, Kratzer W, Laitinen J, Lamina C, Leander K, Lee NR, Lichtner P, Lind L, Lindström J, Sin Lo K, Lobbens S, Lorbeer R, Lu Y, Mach F, Magnusson PK, Mahajan A, McArdle WL, McLachlan S, Menni C, Merger S, Mihailov E, Milani L, Moayyeri A, Monda KL, Morken MA, Mulas A, Müller G, Müller-Nurasyid M, Musk AW, Nagaraja R, Nöthen MM, Nolte IM, Pilz S, Rayner NW, Renstrom F, Rettig R, Ried JS, Ripke S, Robertson NR, Rose LM, Sanna S, Scharnagl H, Scholtens S, Schumacher FR, Scott WR, Seufferlein T, Shi J, Vernon Smith A, Smolonska J, Stanton AV, Steinthorsdottir V, Stirrups K, Stringham HM, Sundström J, Swertz MA, Swift AJ, Syvänen AC, Tan ST, Tayo BO, Thorand B, Thorleifsson G, Tyrer JP, Uh HW, Vandenput L, Verhulst FC, Vermeulen SH, Verweij N, Vonk JM, Waite LL, Warren HR, Waterworth D, Weedon MN, Wilkens LR, Willenborg C, Wilsgaard T, Wojczynski MK, Wong A, Wright AF, Zhang Q, Brennan EP, Choi M, Dastani Z, Drong AW, Eriksson P, Franco-Cereceda A, Gådin JR, Gharavi AG, Goddard ME, Handsaker RE, Huang J, Karpe F, Kathiresan S, Keildson S, Kiryluk K, Kubo M, Lee JY, Liang L, Lifton RP, Ma B, McCarroll SA, McKnight AJ, Min JL, Moffatt MF, Montgomery GW, Murabito JM, Nicholson G, Nyholt DR, Okada Y, Perry JR, Dorajoo R, Reinmaa E, Salem RM, Sandholm N, Scott RA, Stolk L, Takahashi A, Tanaka T, Van't Hooft FM, Vinkhuyzen AA, Westra HJ, Zheng W, Zondervan KT, Heath AC, Arveiler D, Bakker SJ, Beilby J, Bergman RN, Blangero J, Bovet P, Campbell H, Caulfield MJ, Cesana G, Chakravarti A, Chasman DI, Chines PS, Collins FS, Crawford DC, Cupples LA, Cusi D, Danesh J, de Faire U, den Ruijter HM, Dominiczak AF, Erbel R, Erdmann J, Eriksson JG, Farrall M, Felix SB, Ferrannini E, Ferrières J, Ford I, Forouhi NG, Forrester T, Franco OH, Gansevoort RT, Gejman PV, Gieger C, Gottesman O, Gudnason V, Gyllensten U, Hall AS, Harris TB, Hattersley AT, Hicks AA, Hindorff LA, Hingorani AD, Hofman A, Homuth G, Hovingh GK, Humphries SE, Hunt SC, Hyppönen E, Illig T, Jacobs KB, Jarvelin MR, Jöckel KH, Johansen B, Jousilahti P, Jukema JW, Jula AM, Kaprio J, Kastelein JJ, Keinanen-Kiukaanniemi SM, Kiemeney LA, Knekt P, Kooner JS, Kooperberg C, Kovacs P, Kraja AT, Kumari M, Kuusisto J, Lakka TA, Langenberg C, Le Marchand L, Lehtimäki T, Lyssenko V, Männistö S, Marette A, Matise TC, McKenzie CA, McKnight B, Moll FL, Morris AD, Morris AP, Murray JC, Nelis M, Ohlsson C, et al. Genetic stuView Related Profiles.

Murabito, Joanne
Cupples, L
Heard-Costa, Nancy
Ramachandran, Vasan

PMID: 25673413; PMCID: PMC4382211; DOI: 10.1038/nature14177;

Fox ER, Musani SK, Samdarshi TE, Taylor JK, Beard WL, Sarpong DF, Xanthakis V, McClendon EE, Liebson PR, Skelton TN, Butler KR, Mosley TH, Taylor H, Vasan RS. Clinical correlates and prognostic significance of change in standardized left ventricular mass in a community-based cohort of African Americans. J Am Heart Assoc. 2015 Feb; 4(2).View Related Profiles.

Xanthakis, Vanessa
Ramachandran, Vasan

PMID: 25655570; PMCID: PMC4345860; DOI: 10.1161/JAHA.114.001224;

Fufaa GD, Weil EJ, Nelson RG, Hanson RL, Knowler WC, Rovin BH, Wu H, Klein JB, Mifflin TE, Feldman HI, Vasan RS, Kimmel PL, Kusek JW, Mauer M. Urinary monocyte chemoattractant protein-1 and hepcidin and early diabetic nephropathy lesions in type 1 diabetes mellitus. Nephrol Dial Transplant. 2015 Apr; 30(4):599-606. PMID: 25648911; PMCID: PMC4402379; DOI: 10.1093/ndt/gfv012;

Delling FN, Vasan RS. Mitral valve prolapse and glaucoma: a 'floppy' perception? Heart. 2015 Apr; 101(8):584-5. PMID: 25637370; DOI: 10.1136/heartjnl-2014-307229;

Pencina MJ, D'Agostino RB, Zdrojewski T, Williams K, Thanassoulis G, Furberg CD, Peterson ED, Vasan RS, Sniderman AD. Apolipoprotein B improves risk assessment of future coronary heart disease in the Framingham Heart Study beyond LDL-C and non-HDL-C. Eur J Prev Cardiol. 2015 Oct; 22(10):1321-7.View Related Profiles.

Pencina, Michael
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 25633587; DOI: 10.1177/2047487315569411;

Shoamanesh A, Preis SR, Beiser AS, Vasan RS, Benjamin EJ, Kase CS, Wolf PA, DeCarli C, Romero JR, Seshadri S. Inflammatory biomarkers, cerebral microbleeds, and small vessel disease: Framingham Heart Study. Neurology. 2015 Feb 24; 84(8):825-32.View Related Profiles.

Beiser, Alexa
Shoamanesh, Ashkan
Kase, Carlos
Benjamin, Emelia
Romero, Jose
Wolf, Philip
Preis, Sarah
Seshadri, Sudha
Ramachandran, Vasan

PMID: 25632086; PMCID: PMC4345647; DOI: 10.1212/WNL.0000000000001279;

Sud M, Wang X, Austin PC, Lipscombe LL, Newton GE, Tu JV, Vasan RS, Lee DS. Presentation blood glucose and death, hospitalization, and future diabetes risk in patients with acute heart failure syndromes. Eur Heart J. 2015 Apr 14; 36(15):924-31. PMID: 25572328; DOI: 10.1093/eurheartj/ehu462;

Würtz P, Havulinna AS, Soininen P, Tynkkynen T, Prieto-Merino D, Tillin T, Ghorbani A, Artati A, Wang Q, Tiainen M, Kangas AJ, Kettunen J, Kaikkonen J, Mikkilä V, Jula A, Kähönen M, Lehtimäki T, Lawlor DA, Gaunt TR, Hughes AD, Sattar N, Illig T, Adamski J, Wang TJ, Perola M, Ripatti S, Vasan RS, Raitakari OT, Gerszten RE, Casas JP, Chaturvedi N, Ala-Korpela M, Salomaa V. Metabolite profiling and cardiovascular event risk: a prospective study of 3 population-based cohorts. Circulation. 2015 Mar 3; 131(9):774-85. PMID: 25573147; PMCID: PMC4351161; DOI: 10.1161/CIRCULATIONAHA.114.013116;

Musani SK, Fox ER, Kraja A, Bidulescu A, Lieb W, Lin H, Beecham A, Chen MH, Felix JF, Fox CS, Kao WH, Kardia SL, Liu CT, Nalls MA, Rundek T, Sacco RL, Smith J, Sun YV, Wilson G, Zhang Z, Mosley TH, Taylor HA, Vasan RS. Genome-wide association analysis of plasma B-type natriuretic peptide in blacks: the Jackson Heart Study. Circ Cardiovasc Genet. 2015 Feb; 8(1):122-30.View Related Profiles.

Liu, Ching-Ti
Lin, Honghuang
Ramachandran, Vasan

PMID: 25561047; PMCID: PMC4426827; DOI: 10.1161/CIRCGENETICS.114.000900;

Rosenquist KJ, Massaro JM, Pedley A, Long MT, Kreger BE, Vasan RS, Murabito JM, Hoffmann U, Fox CS. Fat quality and incident cardiovascular disease, all-cause mortality, and cancer mortality. J Clin Endocrinol Metab. 2015 Jan; 100(1):227-34.View Related Profiles.

Kreger, Bernard
Murabito, Joanne
Massaro, Joseph
Long, Michelle
Ramachandran, Vasan

PMID: 25226289; DOI: 10.1210/jc.2013-4296;

Nayor M, Vasan RS. Endogenous carbon monoxide and cardiometabolic risk: can measuring exhaled carbon monoxide be used to refine cardiometabolic risk assessment? Future Cardiol. 2015; 11(1):9-12.View Related Profiles.

Nayor, Matthew
Ramachandran, Vasan

PMID: 25606696; DOI: 10.2217/fca.14.78;

Lieb W, Chen MH, Larson MG, Safa R, Teumer A, Baumeister SE, Lin H, Smith HM, Koch M, Lorbeer R, Völker U, Nauck M, Völzke H, Wallaschofski H, Sawyer DB, Vasan RS. Genome-wide association study for endothelial growth factors. Circ Cardiovasc Genet. 2015 Apr; 8(2):389-97.View Related Profiles.

Lin, Honghuang
Larson, Martin
Ramachandran, Vasan

PMID: 25552591; PMCID: PMC4406801; DOI: 10.1161/CIRCGENETICS.114.000597;

White IR, Rapsomaniki E. Covariate-adjusted measures of discrimination for survival data. Biom J. 2015 Jul; 57(4):592-613. PMID: 25530064; PMCID: PMC4666552; DOI: 10.1002/bimj.201400061;

Kaess BM, Harris WS, Lacey S, Larson MG, Hamburg NM, Vita JA, Robins SJ, Benjamin EJ, Mitchell GF, Vasan RS. The relation of red blood cell fatty acids with vascular stiffness, cardiac structure and left ventricular function: the Framingham Heart Study. Vasc Med. 2015 Feb; 20(1):5-13.View Related Profiles.

Kaess, Bernhard
Benjamin, Emelia
Vita, Joseph
Larson, Martin
Hamburg, Naomi
Robins, Sander
Ramachandran, Vasan

PMID: 25520318; DOI: 10.1177/1358863X14560808;

Lieb W, Chen MH, Teumer A, de Boer RA, Lin H, Fox ER, Musani SK, Wilson JG, Wang TJ, Völzke H, Petersen AK, Meisinger C, Nauck M, Schlesinger S, Li Y, Menard J, Hercberg S, Wichmann HE, Völker U, Rawal R, Bidlingmaier M, Hannemann A, Dörr M, Rettig R, van Gilst WH, van Veldhuisen DJ, Bakker SJ, Navis G, Wallaschofski H, Meneton P, van der Harst P, Reincke M, Vasan RS. Genome-wide meta-analyses of plasma renin activity and concentration reveal association with the kininogen 1 and prekallikrein genes. Circ Cardiovasc Genet. 2015 Feb; 8(1):131-40.View Related Profiles.

Lin, Honghuang
Ramachandran, Vasan

PMID: 25477429; PMCID: PMC4354880; DOI: 10.1161/CIRCGENETICS.114.000613;

Deo RC, Musso G, Tasan M, Tang P, Poon A, Yuan C, Felix JF, Vasan RS, Beroukhim R, De Marco T, Kwok PY, MacRae CA, Roth FP. Prioritizing causal disease genes using unbiased genomic features. Genome Biol. 2014; 15(12):534. PMID: 25633252; PMCID: PMC4279789; DOI: 10.1186/s13059-014-0534-8;

Tintle NL, Pottala JV, Lacey S, Ramachandran V, Westra J, Rogers A, Clark J, Olthoff B, Larson M, Harris W, Shearer GC. A genome-wide association study of saturated, mono- and polyunsaturated red blood cell fatty acids in the Framingham Heart Offspring Study. Prostaglandins Leukot Essent Fatty Acids. 2015 Mar; 94:65-72.View Related Profiles.

Larson, Martin
Ramachandran, Vasan

PMID: 25500335; PMCID: PMC4339483; DOI: 10.1016/j.plefa.2014.11.007;

Andersson C, Vasan RS. Compiling the complement of genes implicated in coronary artery disease. Circ Cardiovasc Genet. 2014 Dec; 7(6):738-40. PMID: 25516622; DOI: 10.1161/CIRCGENETICS.114.000909;

Cheng S, McCabe EL, Larson MG, Chen MH, Osypiuk E, Lehman BT, Stantchev P, Aragam J, Solomon SD, Benjamin EJ, Vasan RS. Left ventricular mechanical function: clinical correlates, heritability, and association with parental heart failure. Eur J Heart Fail. 2015 Jan; 17(1):44-50.View Related Profiles.

Benjamin, Emelia
Osypiuk, Ewa
Aragam, Jayashri
Larson, Martin
Ramachandran, Vasan

PMID: 25445300; DOI: 10.1002/ejhf.202;

Franklin SS, Gokhale SS, Chow VH, Larson MG, Levy D, Vasan RS, Mitchell GF, Wong ND. Does low diastolic blood pressure contribute to the risk of recurrent hypertensive cardiovascular disease events? The Framingham Heart Study. Hypertension. 2015 Feb; 65(2):299-305.View Related Profiles.

Levy, Daniel
Larson, Martin
Ramachandran, Vasan

PMID: 25421982; DOI: 10.1161/HYPERTENSIONAHA.114.04581;

Cooper LL, Rong J, Benjamin EJ, Larson MG, Levy D, Vita JA, Hamburg NM, Vasan RS, Mitchell GF. Components of hemodynamic load and cardiovascular events: the Framingham Heart Study. Circulation. 2015 Jan 27; 131(4):354-61; discussion 361.View Related Profiles.

Levy, Daniel
Benjamin, Emelia
Vita, Joseph
Larson, Martin
Hamburg, Naomi
Ramachandran, Vasan

PMID: 25416177; PMCID: PMC4308473; DOI: 10.1161/CIRCULATIONAHA.114.011357;

Benjamin I, Brown N, Burke G, Correa A, Houser SR, Jones DW, Loscalzo J, Vasan RS, Whitman GR. American Heart Association Cardiovascular Genome-Phenome Study: foundational basis and program. Circulation. 2015 Jan 6; 131(1):100-12. PMID: 25411155; PMCID: PMC4286232; DOI: 10.1161/CIRCULATIONAHA.114.014190;

Tsao CW, Vasan RS. Cardiovascular endocrinology: Growth hormone in CVD prediction--a tall order? Nat Rev Endocrinol. 2015 Jan; 11(1):11-3. PMID: 25404017; DOI: 10.1038/nrendo.2014.204;

Liu C, Dupuis J, Larson MG, Cupples LA, Ordovas JM, Vasan RS, Meigs JB, Jacques PF, Levy D. Revisiting heritability accounting for shared environmental effects and maternal inheritance. Hum Genet. 2015 Feb; 134(2):169-79.View Related Profiles.

Liu, Chunyu
Dupuis, Josee
Cupples, L
Larson, Martin
Ramachandran, Vasan

PMID: 25381465; PMCID: PMC4303043; DOI: 10.1007/s00439-014-1505-6;

Andersson C, Gislason GH, Hlatky MA, Søndergaard KB, Pallisgaard J, Smith JG, Vasan RS, Larson MG, Jensen PF, Køber L, Torp-Pedersen C. A risk score for predicting 30-day mortality in heart failure patients undergoing non-cardiac surgery. Eur J Heart Fail. 2014 Dec; 16(12):1310-6.View Related Profiles.

Larson, Martin
Ramachandran, Vasan

PMID: 25359203; DOI: 10.1002/ejhf.182;

Delling FN, Rong J, Larson MG, Lehman B, Osypiuk E, Stantchev P, Slaugenhaupt SA, Benjamin EJ, Levine RA, Vasan RS. Familial clustering of mitral valve prolapse in the community. Circulation. 2015 Jan 20; 131(3):263-8.View Related Profiles.

Benjamin, Emelia
Osypiuk, Ewa
Rong, Jian
Larson, Martin
Ramachandran, Vasan

PMID: 25361552; PMCID: PMC4301989; DOI: 10.1161/CIRCULATIONAHA.114.012594;

Postmus I, Trompet S, Deshmukh HA, Barnes MR, Li X, Warren HR, Chasman DI, Zhou K, Arsenault BJ, Donnelly LA, Wiggins KL, Avery CL, Griffin P, Feng Q, Taylor KD, Li G, Evans DS, Smith AV, de Keyser CE, Johnson AD, de Craen AJ, Stott DJ, Buckley BM, Ford I, Westendorp RG, Slagboom PE, Sattar N, Munroe PB, Sever P, Poulter N, Stanton A, Shields DC, O'Brien E, Shaw-Hawkins S, Chen YD, Nickerson DA, Smith JD, Dubé MP, Boekholdt SM, Hovingh GK, Kastelein JJ, McKeigue PM, Betteridge J, Neil A, Durrington PN, Doney A, Carr F, Morris A, McCarthy MI, Groop L, Ahlqvist E, Bis JC, Rice K, Smith NL, Lumley T, Whitsel EA, Stürmer T, Boerwinkle E, Ngwa JS, O'Donnell CJ, Vasan RS, Wei WQ, Wilke RA, Liu CT, Sun F, Guo X, Heckbert SR, Post W, Sotoodehnia N, Arnold AM, Stafford JM, Ding J, Herrington DM, Kritchevsky SB, Eiriksdottir G, Launer LJ, Harris TB, Chu AY, Giulianini F, MacFadyen JG, Barratt BJ, Nyberg F, Stricker BH, Uitterlinden AG, Hofman A, Rivadeneira F, Emilsson V, Franco OH, Ridker PM, Gudnason V, Liu Y, Denny JC, Ballantyne CM, Rotter JI, Adrienne Cupples L, Psaty BM, Palmer CN, Tardif JC, Colhoun HM, Hitman G, Krauss RM, Wouter Jukema J, Caulfield MJ. Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins. Nat Commun. 2014; 5:5068.View Related Profiles.

Liu, Ching-Ti
O'Donnell, Christopher
Sun, Fangui
Ramachandran, Vasan

PMID: 25350695; PMCID: PMC4220464; DOI: 10.1038/ncomms6068;

Andersson C, Sullivan L, Benjamin EJ, Aragam J, Jacques P, Cheng S, Vasan RS. Association of soda consumption with subclinical cardiac remodeling in the Framingham heart study. Metabolism. 2015 Feb; 64(2):208-12.View Related Profiles.

Benjamin, Emelia
Aragam, Jayashri
Sullivan, Lisa
Ramachandran, Vasan

PMID: 25456096; PMCID: PMC4277910; DOI: 10.1016/j.metabol.2014.10.009;

Fufaa GD, Weil EJ, Nelson RG, Hanson RL, Bonventre JV, Sabbisetti V, Waikar SS, Mifflin TE, Zhang X, Xie D, Hsu CY, Feldman HI, Coresh J, Vasan RS, Kimmel PL, Liu KD. Association of urinary KIM-1, L-FABP, NAG and NGAL with incident end-stage renal disease and mortality in American Indians with type 2 diabetes mellitus. Diabetologia. 2015 Jan; 58(1):188-98.View Related Profiles.

Waikar, Sushrut
Ramachandran, Vasan

PMID: 25316431; PMCID: PMC4258130; DOI: 10.1007/s00125-014-3389-3;

Lorbeer R, Baumeister SE, Dörr M, Felix SB, Nauck M, Grotevendt A, Markus MR, von Sarnowski B, Völzke H, Vasan RS, Wallaschofski H, Lieb W. Angiopoietin-2, its soluble receptor Tie-2 and subclinical cardiovascular disease in a population-based sample. Heart. 2015 Feb; 101(3):178-84. PMID: 25286927; DOI: 10.1136/heartjnl-2014-306056;

Xanthakis V, Enserro DM, Murabito JM, Polak JF, Wollert KC, Januzzi JL, Wang TJ, Tofler G, Vasan RS. Ideal cardiovascular health: associations with biomarkers and subclinical disease and impact on incidence of cardiovascular disease in the Framingham Offspring Study. Circulation. 2014 Nov 4; 130(19):1676-83.View Related Profiles.

Murabito, Joanne
Polak, Joseph
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Ramachandran, Vasan

PMID: 25274000; DOI: 10.1161/CIRCULATIONAHA.114.009273;

Zakharov MN, Bhasin S, Travison TG, Xue R, Ulloor J, Vasan RS, Carter E, Wu F, Jasuja R. A multi-step, dynamic allosteric model of testosterone's binding to sex hormone binding globulin. Mol Cell Endocrinol. 2015 Jan 5; 399:190-200.View Related Profiles.

Ulloor, Jagadish
Zakharov, Mikhail
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Travison, Thomas
Ramachandran, Vasan

PMID: 25240469; DOI: 10.1016/j.mce.2014.09.001;

Lüneburg N, Lieb W, Zeller T, Chen MH, Maas R, Carter AM, Xanthakis V, Glazer NL, Schwedhelm E, Seshadri S, Ikram MA, Longstreth WT, Fornage M, König IR, Loley C, Ojeda FM, Schillert A, Wang TJ, Sticht H, Kittel A, König J, Benjamin EJ, Sullivan LM, Bernges I, Anderssohn M, Ziegler A, Gieger C, Illig T, Meisinger C, Wichmann HE, Wild PS, Schunkert H, Psaty BM, Wiggins KL, Heckbert SR, Smith N, Lackner K, Lunetta KL, Blankenberg S, Erdmann J, Munzel T, Grant PJ, Vasan RS, Böger RH. Genome-wide association study of L-arginine and dimethylarginines reveals novel metabolic pathway for symmetric dimethylarginine. Circ Cardiovasc Genet. 2014 Dec; 7(6):864-72.View Related Profiles.

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Lunetta, Kathryn
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Xanthakis, Vanessa
Ramachandran, Vasan

PMID: 25245031; DOI: 10.1161/CIRCGENETICS.113.000264;

Gopal DM, Larson MG, Januzzi JL, Cheng S, Ghorbani A, Wollert KC, Kempf T, D'Agostino RB, Polak JF, Ramachandran VS, Wang TJ, Ho JE. Biomarkers of cardiovascular stress and subclinical atherosclerosis in the community. Clin Chem. 2014 Nov; 60(11):1402-8.View Related Profiles.

Gopal, Deepa
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PMID: 25237063; PMCID: PMC4376479; DOI: 10.1373/clinchem.2014.227116;

Andersson C, Lyass A, Vasan RS, Massaro JM, D'Agostino RB, Robins SJ. Long-term risk of cardiovascular events across a spectrum of adverse major plasma lipid combinations in the Framingham Heart Study. Am Heart J. 2014 Dec; 168(6):878-83.e1.View Related Profiles.

Massaro, Joseph
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PMID: 25458651; DOI: 10.1016/j.ahj.2014.08.007;

Tsao CW, Pencina KM, Massaro JM, Benjamin EJ, Levy D, Vasan RS, Hoffmann U, O'Donnell CJ, Mitchell GF. Cross-sectional relations of arterial stiffness, pressure pulsatility, wave reflection, and arterial calcification. Arterioscler Thromb Vasc Biol. 2014 Nov; 34(11):2495-500.View Related Profiles.

O'Donnell, Christopher
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PMID: 25169933; PMCID: PMC4199901; DOI: 10.1161/ATVBAHA.114.303916;

Lieb W, Gona P, Larson MG, Aragam J, Zile MR, Cheng S, Benjamin EJ, Vasan RS. The natural history of left ventricular geometry in the community: clinical correlates and prognostic significance of change in LV geometric pattern. JACC Cardiovasc Imaging. 2014 Sep; 7(9):870-8.View Related Profiles.

Benjamin, Emelia
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PMID: 25129518; PMCID: PMC4163746; DOI: 10.1016/j.jcmg.2014.05.008;

Andersson C, Vasan RS. Lower is not always better? Blood pressure treatment targets revisited. J Am Coll Cardiol. 2014 Aug 12; 64(6):598-600. PMID: 25104530; DOI: 10.1016/j.jacc.2014.04.066;

Ljungman PL, Wilker EH, Rice MB, Schwartz J, Gold DR, Koutrakis P, Vita JA, Mitchell GF, Vasan RS, Benjamin EJ, Mittleman MA, Hamburg NM. Short-term exposure to air pollution and digital vascular function. Am J Epidemiol. 2014 Sep 1; 180(5):482-9.View Related Profiles.

Benjamin, Emelia
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PMID: 25100647; PMCID: PMC4143083; DOI: 10.1093/aje/kwu161;

Torjesen AA, Wang N, Larson MG, Hamburg NM, Vita JA, Levy D, Benjamin EJ, Vasan RS, Mitchell GF. Forward and backward wave morphology and central pressure augmentation in men and women in the Framingham Heart Study. Hypertension. 2014 Aug; 64(2):259-65.View Related Profiles.

Benjamin, Emelia
Vita, Joseph
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PMID: 24866142; PMCID: PMC4184952; DOI: 10.1161/HYPERTENSIONAHA.114.03371;

Rebholz CM, Grams ME, Coresh J, Selvin E, Inker LA, Levey AS, Kimmel PL, Vasan RS, Eckfeldt JH, Feldman HI, Hsu CY, Lutsey PL. Serum fibroblast growth factor-23 is associated with incident kidney disease. J Am Soc Nephrol. 2015 Jan; 26(1):192-200. PMID: 25060052; PMCID: PMC4279743; DOI: 10.1681/ASN.2014020218;

Sinner MF, Stepas KA, Moser CB, Krijthe BP, Aspelund T, Sotoodehnia N, Fontes JD, Janssens AC, Kronmal RA, Magnani JW, Witteman JC, Chamberlain AM, Lubitz SA, Schnabel RB, Vasan RS, Wang TJ, Agarwal SK, McManus DD, Franco OH, Yin X, Larson MG, Burke GL, Launer LJ, Hofman A, Levy D, Gottdiener JS, Kääb S, Couper D, Harris TB, Astor BC, Ballantyne CM, Hoogeveen RC, Arai AE, Soliman EZ, Ellinor PT, Stricker BH, Gudnason V, Heckbert SR, Pencina MJ, Benjamin EJ, Alonso A. B-type natriuretic peptide and C-reactive protein in the prediction of atrial fibrillation risk: the CHARGE-AF Consortium of community-based cohort studies. Europace. 2014 Oct; 16(10):1426-33.View Related Profiles.

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PMID: 25037055; PMCID: PMC4197895; DOI: 10.1093/europace/euu175;

Rutter MK, Sullivan LM, Fox CS, Wilson PW, Nathan DM, Vasan RS, D'Agostino RB, Meigs JB. Baseline levels, and changes over time in body mass index and fasting insulin, and their relationship to change in metabolic trait clustering. Metab Syndr Relat Disord. 2014 Sep; 12(7):372-80.View Related Profiles.

Sullivan, Lisa
D'Agostino, Ralph
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PMID: 25007010; PMCID: PMC4209491; DOI: 10.1089/met.2013.0148;

Andersson C, Vasan RS. Epidemiology of heart failure with preserved ejection fraction. Heart Fail Clin. 2014 Jul; 10(3):377-88. PMID: 24975902; PMCID: PMC4084609; DOI: 10.1016/j.hfc.2014.04.003;

Ganesh SK, Chasman DI, Larson MG, Guo X, Verwoert G, Bis JC, Gu X, Smith AV, Yang ML, Zhang Y, Ehret G, Rose LM, Hwang SJ, Papanicolau GJ, Sijbrands EJ, Rice K, Eiriksdottir G, Pihur V, Ridker PM, Vasan RS, Newton-Cheh C, Raffel LJ, Amin N, Rotter JI, Liu K, Launer LJ, Xu M, Caulfield M, Morrison AC, Johnson AD, Vaidya D, Dehghan A, Li G, Bouchard C, Harris TB, Zhang H, Boerwinkle E, Siscovick DS, Gao W, Uitterlinden AG, Rivadeneira F, Hofman A, Willer CJ, Franco OH, Huo Y, Witteman JC, Munroe PB, Gudnason V, Palmas W, van Duijn C, Fornage M, Levy D, Psaty BM, Chakravarti A. Effects of long-term averaging of quantitative blood pressure traits on the detection of genetic associations. Am J Hum Genet. 2014 Jul 3; 95(1):49-65.View Related Profiles.

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Ramachandran, Vasan

PMID: 24975945; PMCID: PMC4085637; DOI: 10.1016/j.ajhg.2014.06.002;

Simino J, Shi G, Bis JC, Chasman DI, Ehret GB, Gu X, Guo X, Hwang SJ, Sijbrands E, Smith AV, Verwoert GC, Bragg-Gresham JL, Cadby G, Chen P, Cheng CY, Corre T, de Boer RA, Goel A, Johnson T, Khor CC, Lluís-Ganella C, Luan J, Lyytikäinen LP, Nolte IM, Sim X, Sõber S, van der Most PJ, Verweij N, Zhao JH, Amin N, Boerwinkle E, Bouchard C, Dehghan A, Eiriksdottir G, Elosua R, Franco OH, Gieger C, Harris TB, Hercberg S, Hofman A, James AL, Johnson AD, Kähönen M, Khaw KT, Kutalik Z, Larson MG, Launer LJ, Li G, Liu J, Liu K, Morrison AC, Navis G, Ong RT, Papanicolau GJ, Penninx BW, Psaty BM, Raffel LJ, Raitakari OT, Rice K, Rivadeneira F, Rose LM, Sanna S, Scott RA, Siscovick DS, Stolk RP, Uitterlinden AG, Vaidya D, van der Klauw MM, Vasan RS, Vithana EN, Völker U, Völzke H, Watkins H, Young TL, Aung T, Bochud M, Farrall M, Hartman CA, Laan M, Lakatta EG, Lehtimäki T, Loos RJ, Lucas G, Meneton P, Palmer LJ, Rettig R, Snieder H, Tai ES, Teo YY, van der Harst P, Wareham NJ, Wijmenga C, Wong TY, Fornage M, Gudnason V, Levy D, Palmas W, Ridker PM, Rotter JI, van Duijn CM, Witteman JC, Chakravarti A, Rao DC. Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia. Am J Hum Genet. 2014 Jul 3; 95(1):24-38.View Related Profiles.

Larson, Martin
Ramachandran, Vasan

PMID: 24954895; PMCID: PMC4085636; DOI: 10.1016/j.ajhg.2014.05.010;

Evans DS, Cailotto F, Parimi N, Valdes AM, Castaño-Betancourt MC, Liu Y, Kaplan RC, Bidlingmaier M, Vasan RS, Teumer A, Tranah GJ, Nevitt MC, Cummings SR, Orwoll ES, Barrett-Connor E, Renner JB, Jordan JM, Doherty M, Doherty SA, Uitterlinden AG, van Meurs JB, Spector TD, Lories RJ, Lane NE. Genome-wide association and functional studies identify a role for IGFBP3 in hip osteoarthritis. Ann Rheum Dis. 2015 Oct; 74(10):1861-7. PMID: 24928840; PMCID: PMC4449305; DOI: 10.1136/annrheumdis-2013-205020;

Thankappan KR, Shah B, Mathur P, Sarma PS, Srinivas G, Mini GK, Daivadanam M, Soman B, Vasan RS. Authors' response. Indian J Med Res. 2014 Jun; 139(6):962. PMID: 25265651; PMCID: PMC4165019

Delling FN, Vasan RS. Epidemiology and pathophysiology of mitral valve prolapse: new insights into disease progression, genetics, and molecular basis. Circulation. 2014 May 27; 129(21):2158-70. PMID: 24867995; PMCID: PMC4052751; DOI: 10.1161/CIRCULATIONAHA.113.006702;

Ho JE, Larson MG, Ghorbani A, Cheng S, Coglianese EE, Vasan RS, Wang TJ. Long-term cardiovascular risks associated with an elevated heart rate: the Framingham Heart Study. J Am Heart Assoc. 2014 Jun; 3(3):e000668.View Related Profiles.

Ho, Jennifer
Larson, Martin
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PMID: 24811610; PMCID: PMC4309047; DOI: 10.1161/JAHA.113.000668;

Zachariah JP, Graham DA, de Ferranti SD, Vasan RS, Newburger JW, Mitchell GF. Temporal trends in pulse pressure and mean arterial pressure during the rise of pediatric obesity in US children. J Am Heart Assoc. 2014 Jun; 3(3):e000725. PMID: 24811611; PMCID: PMC4309055; DOI: 10.1161/JAHA.113.000725;

Paul L, Jacques PF, Aviv A, Vasan RS, D'Agostino RB, Levy D, Selhub J. High plasma folate is negatively associated with leukocyte telomere length in Framingham Offspring cohort. Eur J Nutr. 2015 Mar; 54(2):235-41.View Related Profiles.

D'Agostino, Ralph
Ramachandran, Vasan

PMID: 24793435; PMCID: PMC4218881; DOI: 10.1007/s00394-014-0704-1;

Amabile N, Cheng S, Renard JM, Larson MG, Ghorbani A, McCabe E, Griffin G, Guerin C, Ho JE, Shaw SY, Cohen KS, Vasan RS, Tedgui A, Boulanger CM, Wang TJ. Association of circulating endothelial microparticles with cardiometabolic risk factors in the Framingham Heart Study. Eur Heart J. 2014 Nov 7; 35(42):2972-9.View Related Profiles.

Ho, Jennifer
Larson, Martin
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PMID: 24742886; PMCID: PMC4223610; DOI: 10.1093/eurheartj/ehu153;

Xanthakis V, Sullivan LM, Vasan RS, Benjamin EJ, Massaro JM, D'Agostino RB, Pencina MJ. Assessing the incremental predictive performance of novel biomarkers over standard predictors. Stat Med. 2014 Jul 10; 33(15):2577-84.View Related Profiles.

Benjamin, Emelia
Massaro, Joseph
Sullivan, Lisa
Pencina, Michael
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Ramachandran, Vasan

PMID: 24719270; PMCID: PMC4047140; DOI: 10.1002/sim.6165;

Westwood AJ, Beiser A, Decarli C, Harris TB, Chen TC, He XM, Roubenoff R, Pikula A, Au R, Braverman LE, Wolf PA, Vasan RS, Seshadri S. Insulin-like growth factor-1 and risk of Alzheimer dementia and brain atrophy. Neurology. 2014 May 6; 82(18):1613-9.View Related Profiles.

Pikula, Aleksandra
Beiser, Alexa
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Chen, Tai
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PMID: 24706014; PMCID: PMC4013812; DOI: 10.1212/WNL.0000000000000382;

Wilker EH, Ljungman PL, Rice MB, Kloog I, Schwartz J, Gold DR, Koutrakis P, Vita JA, Mitchell GF, Vasan RS, Benjamin EJ, Hamburg NM, Mittleman MA. Relation of long-term exposure to air pollution to brachial artery flow-mediated dilation and reactive hyperemia. Am J Cardiol. 2014 Jun 15; 113(12):2057-63.View Related Profiles.

Benjamin, Emelia
Vita, Joseph
Hamburg, Naomi
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PMID: 24793676; PMCID: PMC4066389; DOI: 10.1016/j.amjcard.2014.03.048;

Ellis J, Lange EM, Li J, Dupuis J, Baumert J, Walston JD, Keating BJ, Durda P, Fox ER, Palmer CD, Meng YA, Young T, Farlow DN, Schnabel RB, Marzi CS, Larkin E, Martin LW, Bis JC, Auer P, Ramachandran VS, Gabriel SB, Willis MS, Pankow JS, Papanicolaou GJ, Rotter JI, Ballantyne CM, Gross MD, Lettre G, Wilson JG, Peters U, Koenig W, Tracy RP, Redline S, Reiner AP, Benjamin EJ, Lange LA. Large multiethnic Candidate Gene Study for C-reactive protein levels: identification of a novel association at CD36 in African Americans. Hum Genet. 2014 Aug; 133(8):985-95.View Related Profiles.

Benjamin, Emelia
Dupuis, Josee
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PMID: 24643644; PMCID: PMC4104766; DOI: 10.1007/s00439-014-1439-z;

Magnani JW, Moser CB, Murabito JM, Sullivan LM, Wang N, Ellinor PT, Vasan RS, Benjamin EJ, Coviello AD. Association of sex hormones, aging, and atrial fibrillation in men: the Framingham Heart Study. Circ Arrhythm Electrophysiol. 2014 Apr; 7(2):307-12.View Related Profiles.

Coviello, Andrea
Benjamin, Emelia
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PMID: 24610804; PMCID: PMC4035016; DOI: 10.1161/CIRCEP.113.001322;

Andersson C, Vasan RS. Is there a role for coronary artery calcium scoring for management of asymptomatic patients at risk for coronary artery disease?: Clinical risk scores are sufficient to define primary prevention treatment strategies among asymptomatic patients. Circ Cardiovasc Imaging. 2014 Mar; 7(2):390-7; discussion 397. PMID: 24642921; PMCID: PMC4154564; DOI: 10.1161/CIRCIMAGING.113.000470;

Ho JE, Yin X, Levy D, Vasan RS, Magnani JW, Ellinor PT, McManus DD, Lubitz SA, Larson MG, Benjamin EJ. Galectin 3 and incident atrial fibrillation in the community. Am Heart J. 2014 May; 167(5):729-34.e1.View Related Profiles.

Benjamin, Emelia
Magnani, Jared
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PMID: 24766984; PMCID: PMC4007212; DOI: 10.1016/j.ahj.2014.02.009;

Cheng S, Enserro D, Xanthakis V, Sullivan LM, Murabito JM, Benjamin EJ, Polak JF, O'Donnell CJ, Wolf PA, O'Connor GT, Keaney JF, Vasan RS. Association of exhaled carbon monoxide with subclinical cardiovascular disease and their conjoint impact on the incidence of cardiovascular outcomes. Eur Heart J. 2014 Nov 7; 35(42):2980-7.View Related Profiles.

O'Donnell, Christopher
Benjamin, Emelia
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PMID: 24574370; PMCID: PMC4271053; DOI: 10.1093/eurheartj/ehu052;

Tragante V, Barnes MR, Ganesh SK, Lanktree MB, Guo W, Franceschini N, Smith EN, Johnson T, Holmes MV, Padmanabhan S, Karczewski KJ, Almoguera B, Barnard J, Baumert J, Chang YP, Elbers CC, Farrall M, Fischer ME, Gaunt TR, Gho JM, Gieger C, Goel A, Gong Y, Isaacs A, Kleber ME, Mateo Leach I, McDonough CW, Meijs MF, Melander O, Nelson CP, Nolte IM, Pankratz N, Price TS, Shaffer J, Shah S, Tomaszewski M, van der Most PJ, Van Iperen EP, Vonk JM, Witkowska K, Wong CO, Zhang L, Beitelshees AL, Berenson GS, Bhatt DL, Brown M, Burt A, Cooper-DeHoff RM, Connell JM, Cruickshanks KJ, Curtis SP, Davey-Smith G, Delles C, Gansevoort RT, Guo X, Haiqing S, Hastie CE, Hofker MH, Hovingh GK, Kim DS, Kirkland SA, Klein BE, Klein R, Li YR, Maiwald S, Newton-Cheh C, O'Brien ET, Onland-Moret NC, Palmas W, Parsa A, Penninx BW, Pettinger M, Vasan RS, Ranchalis JE, M Ridker P, Rose LM, Sever P, Shimbo D, Steele L, Stolk RP, Thorand B, Trip MD, van Duijn CM, Verschuren WM, Wijmenga C, Wyatt S, Young JH, Zwinderman AH, Bezzina CR, Boerwinkle E, Casas JP, Caulfield MJ, Chakravarti A, Chasman DI, Davidson KW, Doevendans PA, Dominiczak AF, FitzGerald GA, Gums JG, Fornage M, Hakonarson H, Halder I, Hillege HL, Illig T, Jarvik GP, Johnson JA, Kastelein JJ, Koenig W, Kumari M, März W, Murray SS, O'Connell JR, Oldehinkel AJ, Pankow JS, Rader DJ, Redline S, Reilly MP, Schadt EE, Kottke-Marchant K, Snieder H, Snyder M, Stanton AV, Tobin MD, Uitterlinden AG, van der Harst P, van der Schouw YT, Samani NJ, Watkins H, Johnson AD, Reiner AP, Zhu X, de Bakker PI, Levy D, Asselbergs FW, Munroe PB, Keating BJ. Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci. Am J Hum Genet. 2014 Mar 6; 94(3):349-60. PMID: 24560520; PMCID: PMC3951943; DOI: 10.1016/j.ajhg.2013.12.016;

Fox CS, Pencina MJ, Heard-Costa NL, Shrader P, Jaquish C, O'Donnell CJ, Vasan RS, Cupples LA, D'Agostino RB. Trends in the association of parental history of obesity over 60 years. Obesity (Silver Spring). 2014 Mar; 22(3):919-24.View Related Profiles.

O'Donnell, Christopher
Cupples, L
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PMID: 23836774; PMCID: PMC3887126; DOI: 10.1002/oby.20564;

MacRae CA, Vasan RS. Clinically relevant functional annotation of genotype. Circ Cardiovasc Genet. 2014 Feb; 7(1):2-3. PMID: 24550428; PMCID: PMC4188549; DOI: 10.1161/CIRCGENETICS.114.000506;

Roberts LD, Boström P, O'Sullivan JF, Schinzel RT, Lewis GD, Dejam A, Lee YK, Palma MJ, Calhoun S, Georgiadi A, Chen MH, Ramachandran VS, Larson MG, Bouchard C, Rankinen T, Souza AL, Clish CB, Wang TJ, Estall JL, Soukas AA, Cowan CA, Spiegelman BM, Gerszten RE. ß-Aminoisobutyric acid induces browning of white fat and hepatic ß-oxidation and is inversely correlated with cardiometabolic risk factors. Cell Metab. 2014 Jan 7; 19(1):96-108.View Related Profiles.

Larson, Martin
Ramachandran, Vasan

PMID: 24411942; PMCID: PMC4017355; DOI: 10.1016/j.cmet.2013.12.003;

Weinstein G, Beiser AS, Choi SH, Preis SR, Chen TC, Vorgas D, Au R, Pikula A, Wolf PA, DeStefano AL, Vasan RS, Seshadri S. Serum brain-derived neurotrophic factor and the risk for dementia: the Framingham Heart Study. JAMA Neurol. 2014 Jan; 71(1):55-61.View Related Profiles.

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Au, Rhoda
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Chen, Tai
Ramachandran, Vasan

PMID: 24276217; PMCID: PMC4056186; DOI: 10.1001/jamaneurol.2013.4781;

Ganesh SK, Arnett DK, Assimes TL, Assimes TL, Basson CT, Chakravarti A, Ellinor PT, Engler MB, Goldmuntz E, Herrington DM, Hershberger RE, Hong Y, Johnson JA, Kittner SJ, McDermott DA, Meschia JF, Mestroni L, O'Donnell CJ, Psaty BM, Vasan RS, Ruel M, Shen WK, Terzic A, Waldman SA. Genetics and genomics for the prevention and treatment of cardiovascular disease: update: a scientific statement from the American Heart Association. Circulation. 2013 Dec 24; 128(25):2813-51.View Related Profiles.

O'Donnell, Christopher
Ramachandran, Vasan

PMID: 24297835; DOI: 10.1161/01.cir.0000437913.98912.1d;

Tsao CW, Vasan RS. Imaging of arterial inflammation: keeping our cool on a hot topic. JACC Cardiovasc Imaging. 2013 Dec; 6(12):1260-2. PMID: 24332279; DOI: 10.1016/j.jcmg.2013.09.010;

Ben-Shlomo Y, Spears M, Boustred C, May M, Anderson SG, Benjamin EJ, Boutouyrie P, Cameron J, Chen CH, Cruickshank JK, Hwang SJ, Lakatta EG, Laurent S, Maldonado J, Mitchell GF, Najjar SS, Newman AB, Ohishi M, Pannier B, Pereira T, Vasan RS, Shokawa T, Sutton-Tyrell K, Verbeke F, Wang KL, Webb DJ, Willum Hansen T, Zoungas S, McEniery CM, Cockcroft JR, Wilkinson IB. Aortic pulse wave velocity improves cardiovascular event prediction: an individual participant meta-analysis of prospective observational data from 17,635 subjects. J Am Coll Cardiol. 2014 Feb 25; 63(7):636-46.View Related Profiles.

Benjamin, Emelia
Hwang, Shih-Jen
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PMID: 24239664; DOI: 10.1016/j.jacc.2013.09.063;

Xanthakis V, Larson MG, Wollert KC, Aragam J, Cheng S, Ho J, Coglianese E, Levy D, Colucci WS, Michael Felker G, Benjamin EJ, Januzzi JL, Wang TJ, Vasan RS. Association of novel biomarkers of cardiovascular stress with left ventricular hypertrophy and dysfunction: implications for screening. J Am Heart Assoc. 2013; 2(6):e000399.View Related Profiles.

Benjamin, Emelia
Aragam, Jayashri
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PMID: 24200688; PMCID: PMC3886765; DOI: 10.1161/JAHA.113.000399;

Evans DM, Brion MJ, Paternoster L, Kemp JP, McMahon G, Munafò M, Whitfield JB, Medland SE, Montgomery GW, Timpson NJ, St Pourcain B, Lawlor DA, Martin NG, Dehghan A, Hirschhorn J, Smith GD. Mining the human phenome using allelic scores that index biological intermediates. PLoS Genet. 2013 Oct; 9(10):e1003919.View Related Profiles.

Preis, Sarah
Ramachandran, Vasan

PMID: 24204319; PMCID: PMC3814299; DOI: 10.1371/journal.pgen.1003919;

Wang T, Zhou B, Guo T, Bidlingmaier M, Wallaschofski H, Teumer A, Vasan RS, Kaplan RC. A robust method for genome-wide association meta-analysis with the application to circulating insulin-like growth factor I concentrations. Genet Epidemiol. 2014 Feb; 38(2):162-71. PMID: 24446417; PMCID: PMC4049273; DOI: 10.1002/gepi.21766;

Delling FN, Gona P, Larson MG, Lehman B, Manning WJ, Levine RA, Benjamin EJ, Vasan RS. Mild expression of mitral valve prolapse in the Framingham offspring: expanding the phenotypic spectrum. J Am Soc Echocardiogr. 2014 Jan; 27(1):17-23.View Related Profiles.

Benjamin, Emelia
Larson, Martin
Ramachandran, Vasan

PMID: 24206636; DOI: 10.1016/j.echo.2013.09.015;

Rienstra M, Yin X, Larson MG, Fontes JD, Magnani JW, McManus DD, McCabe EL, Coglianese EE, Amponsah M, Ho JE, Januzzi JL, Wollert KC, Fradley MG, Vasan RS, Ellinor PT, Wang TJ, Benjamin EJ. Relation between soluble ST2, growth differentiation factor-15, and high-sensitivity troponin I and incident atrial fibrillation. Am Heart J. 2014 Jan; 167(1):109-115.e2.View Related Profiles.

Benjamin, Emelia
Magnani, Jared
Ho, Jennifer
Larson, Martin
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PMID: 24332149; PMCID: PMC3884900; DOI: 10.1016/j.ahj.2013.10.003;

Velagaleti RS, Gona P, Pencina MJ, Aragam J, Wang TJ, Levy D, D'Agostino RB, Lee DS, Kannel WB, Benjamin EJ, Vasan RS. Left ventricular hypertrophy patterns and incidence of heart failure with preserved versus reduced ejection fraction. Am J Cardiol. 2014 Jan 1; 113(1):117-22.View Related Profiles.

Benjamin, Emelia
Aragam, Jayashri
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Ramachandran, Vasan

PMID: 24210333; PMCID: PMC3881171; DOI: 10.1016/j.amjcard.2013.09.028;

Thorgeirsson TE, Gudbjartsson DF, Sulem P, Besenbacher S, Styrkarsdottir U, Thorleifsson G, Walters GB, Furberg H, Sullivan PF, Marchini J, McCarthy MI, Steinthorsdottir V, Thorsteinsdottir U, Stefansson K. A common biological basis of obesity and nicotine addiction. Transl Psychiatry. 2013; 3:e308. PMID: 24084939; PMCID: PMC3818010; DOI: 10.1038/tp.2013.81;

Mahmood SS, Levy D, Vasan RS, Wang TJ. The Framingham Heart Study and the epidemiology of cardiovascular disease: a historical perspective. Lancet. 2014 Mar 15; 383(9921):999-1008. PMID: 24084292; PMCID: PMC4159698; DOI: 10.1016/S0140-6736(13)61752-3;

Armah KA, Chang CC, Baker JV, Ramachandran VS, Budoff MJ, Crane HM, Gibert CL, Goetz MB, Leaf DA, McGinnis KA, Oursler KK, Rimland D, Rodriguez-Barradas MC, Sico JJ, Warner AL, Hsue PY, Kuller LH, Justice AC, Freiberg MS. Prehypertension, hypertension, and the risk of acute myocardial infarction in HIV-infected and -uninfected veterans. Clin Infect Dis. 2014 Jan; 58(1):121-9.View Related Profiles.

So-Armah, Kaku
Ramachandran, Vasan

PMID: 24065316; PMCID: PMC3864500; DOI: 10.1093/cid/cit652;

Haugen IK, Ramachandran VS, Misra D, Neogi T, Niu J, Yang T, Zhang Y, Felson DT. Hand osteoarthritis in relation to mortality and incidence of cardiovascular disease: data from the Framingham heart study. Ann Rheum Dis. 2015 Jan; 74(1):74-81.View Related Profiles.

Felson, David
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Niu, Jingbo
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PMID: 24047870; PMCID: PMC3959628; DOI: 10.1136/annrheumdis-2013-203789;

Kaess BM, Gona P, Larson MG, Cheng S, Aragam J, Kenchaiah S, Benjamin EJ, Vasan RS. Secular trends in echocardiographic left ventricular mass in the community: the Framingham Heart Study. Heart. 2013 Nov; 99(22):1693-8.View Related Profiles.

Kaess, Bernhard
Benjamin, Emelia
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PMID: 24041649

Wang TJ, Ngo D, Psychogios N, Dejam A, Larson MG, Vasan RS, Ghorbani A, O'Sullivan J, Cheng S, Rhee EP, Sinha S, McCabe E, Fox CS, O'Donnell CJ, Ho JE, Florez JC, Magnusson M, Pierce KA, Souza AL, Yu Y, Carter C, Light PE, Melander O, Clish CB, Gerszten RE. 2-Aminoadipic acid is a biomarker for diabetes risk. J Clin Invest. 2013 Oct 1; 123(10):4309-17.View Related Profiles.

O'Donnell, Christopher
Ho, Jennifer
Larson, Martin
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PMID: 24091325; PMCID: PMC3784523; DOI: 10.1172/JCI64801;

Ho JE, Chen WY, Chen MH, Larson MG, McCabe EL, Cheng S, Ghorbani A, Coglianese E, Emilsson V, Johnson AD, Walter S, Franceschini N, O'Donnell CJ, Dehghan A, Lu C, Levy D, Newton-Cheh C, Lin H, Felix JF, Schreiter ER, Vasan RS, Januzzi JL, Lee RT, Wang TJ, Assimes TL, Deloukas P, Erdmann J, Holm H, Kathiresan S, König IR, McPherson R, Reilly MP, Roberts R, Samani NJ, Schunkert H, Stewart AF. Common genetic variation at the IL1RL1 locus regulates IL-33/ST2 signaling. J Clin Invest. 2013 Oct 1; 123(10):4208-18.View Related Profiles.

O'Donnell, Christopher
Lin, Honghuang
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Cupples, L
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Chen, Ming-Huei
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PMID: 23999434; PMCID: PMC3784527; DOI: 10.1172/JCI67119;

Lieb W, Vasan RS. Genetics of coronary artery disease. Circulation. 2013 Sep 3; 128(10):1131-8. PMID: 24002717

O'Seaghdha CM, Hwang SJ, Larson MG, Meigs JB, Vasan RS, Fox CS. Analysis of a urinary biomarker panel for incident kidney disease and clinical outcomes. J Am Soc Nephrol. 2013 Nov; 24(11):1880-8.View Related Profiles.

Larson, Martin
Hwang, Shih-Jen
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PMID: 23990678; PMCID: PMC3810081; DOI: 10.1681/ASN.2013010019;

Cheng S, Larson MG, McCabe EL, Osypiuk E, Lehman BT, Stanchev P, Aragam J, Benjamin EJ, Solomon SD, Vasan RS. Reproducibility of speckle-tracking-based strain measures of left ventricular function in a community-based study. J Am Soc Echocardiogr. 2013 Nov; 26(11):1258-1266.e2.View Related Profiles.

Benjamin, Emelia
Osypiuk, Ewa
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PMID: 23953701; PMCID: PMC3812381; DOI: 10.1016/j.echo.2013.07.002;

Tsao CW, Seshadri S, Beiser AS, Westwood AJ, Decarli C, Au R, Himali JJ, Hamburg NM, Vita JA, Levy D, Larson MG, Benjamin EJ, Wolf PA, Vasan RS, Mitchell GF. Relations of arterial stiffness and endothelial function to brain aging in the community. Neurology. 2013 Sep 10; 81(11):984-91.View Related Profiles.

Beiser, Alexa
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Himali, Jayandra
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Larson, Martin
Hamburg, Naomi
Wolf, Philip
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Seshadri, Sudha
Ramachandran, Vasan

PMID: 23935179; DOI: 10.1212/WNL.0b013e3182a43e1c;

Pikula A, Beiser AS, Chen TC, Preis SR, Vorgias D, DeCarli C, Au R, Kelly-Hayes M, Kase CS, Wolf PA, Vasan RS, Seshadri S. Serum brain-derived neurotrophic factor and vascular endothelial growth factor levels are associated with risk of stroke and vascular brain injury: Framingham Study. Stroke. 2013 Oct; 44(10):2768-75.View Related Profiles.

Pikula, Aleksandra
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Chen, Tai
Ramachandran, Vasan

PMID: 23929745; DOI: 10.1161/STROKEAHA.113.001447;

Cheng S, Larson MG, McCabe EL, Osypiuk E, Lehman BT, Stanchev P, Aragam J, Benjamin EJ, Solomon SD, Vasan RS. Age- and sex-based reference limits and clinical correlates of myocardial strain and synchrony: the Framingham Heart Study. Circ Cardiovasc Imaging. 2013 Sep; 6(5):692-9.View Related Profiles.

Benjamin, Emelia
Osypiuk, Ewa
Aragam, Jayashri
Larson, Martin
Ramachandran, Vasan

PMID: 23917618; DOI: 10.1161/CIRCIMAGING.112.000627;

Lorbeer R, Baumeister SE, Dörr M, Nauck M, Grotevendt A, Völzke H, Vasan RS, Wallaschofski H, Lieb W. Circulating angiopoietin-2, its soluble receptor Tie-2, and mortality in the general population. Eur J Heart Fail. 2013 Dec; 15(12):1327-34. PMID: 23901057; DOI: 10.1093/eurjhf/hft117;

Singh GM, Danaei G, Farzadfar F, Stevens GA, Woodward M, Wormser D, Kaptoge S, Whitlock G, Qiao Q, Lewington S, Di Angelantonio E, Vander Hoorn S, Lawes CM, Ali MK, Mozaffarian D, Ezzati M. The age-specific quantitative effects of metabolic risk factors on cardiovascular diseases and diabetes: a pooled analysis. PLoS One. 2013; 8(7):e65174. PMID: 23935815; PMCID: PMC3728292; DOI: 10.1371/journal.pone.0065174;

Ho JE, Hwang SJ, Wollert KC, Larson MG, Cheng S, Kempf T, Vasan RS, Januzzi JL, Wang TJ, Fox CS. Biomarkers of cardiovascular stress and incident chronic kidney disease. Clin Chem. 2013 Nov; 59(11):1613-20.View Related Profiles.

Ho, Jennifer
Larson, Martin
Hwang, Shih-Jen
Ramachandran, Vasan

PMID: 23873716; PMCID: PMC3972213; DOI: 10.1373/clinchem.2013.205716;

Yaghootkar H, Lamina C, Scott RA, Dastani Z, Hivert MF, Warren LL, Stancáková A, Buxbaum SG, Lyytikäinen LP, Henneman P, Wu Y, Cheung CY, Pankow JS, Jackson AU, Gustafsson S, Zhao JH, Ballantyne CM, Xie W, Bergman RN, Boehnke M, el Bouazzaoui F, Collins FS, Dunn SH, Dupuis J, Forouhi NG, Gillson C, Hattersley AT, Hong J, Kähönen M, Kuusisto J, Kedenko L, Kronenberg F, Doria A, Assimes TL, Ferrannini E, Hansen T, Hao K, Häring H, Knowles JW, Lindgren CM, Nolan JJ, Paananen J, Pedersen O, Quertermous T, Smith U, Lehtimäki T, Liu CT, Loos RJ, McCarthy MI, Morris AD, Vasan RS, Spector TD, Teslovich TM, Tuomilehto J, van Dijk KW, Viikari JS, Zhu N, Langenberg C, Ingelsson E, Semple RK, Sinaiko AR, Palmer CN, Walker M, Lam KS, Paulweber B, Mohlke KL, van Duijn C, Raitakari OT, Bidulescu A, Wareham NJ, Laakso M, Waterworth DM, Lawlor DA, Meigs JB, Richards JB, Frayling TM. Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes. Diabetes. 2013 Oct; 62(10):3589-98.View Related Profiles.

Liu, Ching-Ti
Dupuis, Josee
Ramachandran, Vasan

PMID: 23835345; PMCID: PMC3781444; DOI: 10.2337/db13-0128;

Rhee EP, Ho JE, Chen MH, Shen D, Cheng S, Larson MG, Ghorbani A, Shi X, Helenius IT, O'Donnell CJ, Souza AL, Deik A, Pierce KA, Bullock K, Walford GA, Vasan RS, Florez JC, Clish C, Yeh JR, Wang TJ, Gerszten RE. A genome-wide association study of the human metabolome in a community-based cohort. Cell Metab. 2013 Jul 2; 18(1):130-43.View Related Profiles.

O'Donnell, Christopher
Ho, Jennifer
Larson, Martin
Chen, Ming-Huei
Ramachandran, Vasan

PMID: 23823483; PMCID: PMC3973158; DOI: 10.1016/j.cmet.2013.06.013;

Ho JE, Larson MG, Ghorbani A, Cheng S, Vasan RS, Wang TJ, Januzzi JL. Soluble ST2 predicts elevated SBP in the community. J Hypertens. 2013 Jul; 31(7):1431-6; discussion 1436.View Related Profiles.

Ho, Jennifer
Larson, Martin
Ramachandran, Vasan

PMID: 23615326; PMCID: PMC3986262; DOI: 10.1097/HJH.0b013e3283611bdf;

Xanthakis V, Sullivan LM, Vasan RS. Multilevel modeling versus cross-sectional analysis for assessing the longitudinal tracking of cardiovascular risk factors over time. Stat Med. 2013 Dec 10; 32(28):5028-38.View Related Profiles.

Sullivan, Lisa
Xanthakis, Vanessa
Ramachandran, Vasan

PMID: 23784950; PMCID: PMC4068405; DOI: 10.1002/sim.5880;

O'Seaghdha CM, Hwang SJ, Ho JE, Vasan RS, Levy D, Fox CS. Elevated galectin-3 precedes the development of CKD. J Am Soc Nephrol. 2013 Sep; 24(9):1470-7.View Related Profiles.

Ho, Jennifer
Hwang, Shih-Jen
Ramachandran, Vasan

PMID: 23766533; PMCID: PMC3752944; DOI: 10.1681/ASN.2012090909;

Britton KA, Wang N, Palmisano J, Corsini E, Schlett CL, Hoffmann U, Larson MG, Vasan RS, Vita JA, Mitchell GF, Benjamin EJ, Hamburg NM, Fox CS. Thoracic periaortic and visceral adipose tissue and their cross-sectional associations with measures of vascular function. Obesity (Silver Spring). 2013 Jul; 21(7):1496-503.View Related Profiles.

Benjamin, Emelia
Vita, Joseph
Larson, Martin
Hamburg, Naomi
Ramachandran, Vasan

PMID: 23754461; PMCID: PMC3742564; DOI: 10.1002/oby.20166;

Adlin EV, Braitman LE, Vasan RS. Bimodal aldosterone distribution in low-renin hypertension. Am J Hypertens. 2013 Sep; 26(9):1076-85. PMID: 23757402; PMCID: PMC3741228; DOI: 10.1093/ajh/hpt091;

Musani SK, Vasan RS, Bidulescu A, Liu J, Xanthakis V, Sims M, Gawalapu RK, Samdarshi TE, Steffes M, Taylor HA, Fox ER. Aldosterone, C-reactive protein, and plasma B-type natriuretic peptide are associated with the development of metabolic syndrome and longitudinal changes in metabolic syndrome components: findings from the Jackson Heart Study. Diabetes Care. 2013 Oct; 36(10):3084-92.View Related Profiles.

Xanthakis, Vanessa
Ramachandran, Vasan

PMID: 23757435; PMCID: PMC3781556; DOI: 10.2337/dc12-2562;

Tsao CW, Vasan RS. Diagnosis: Biomarkers of cardiovascular outcomes--bonanza or bias? Nat Rev Endocrinol. 2013 Jul; 9(7):381-2. PMID: 23689815; DOI: 10.1038/nrendo.2013.99;

Jasuja GK, Travison TG, Davda M, Rose AJ, Zhang A, Kushnir MM, Rockwood AL, Meikle W, Coviello AD, D'Agostino R, Vasan RS, Bhasin S. Circulating estrone levels are associated prospectively with diabetes risk in men of the Framingham Heart Study. Diabetes Care. 2013 Sep; 36(9):2591-6.View Related Profiles.

Rose, Adam
Coviello, Andrea
Zhang, Anqi
Jasuja, Guneet
D'Agostino, Ralph
Bhasin, Shalender
Travison, Thomas
Ramachandran, Vasan

PMID: 23690532; PMCID: PMC3747918; DOI: 10.2337/dc12-2477;

Rhee EP, Clish CB, Ghorbani A, Larson MG, Elmariah S, McCabe E, Yang Q, Cheng S, Pierce K, Deik A, Souza AL, Farrell L, Domos C, Yeh RW, Palacios I, Rosenfield K, Vasan RS, Florez JC, Wang TJ, Fox CS, Gerszten RE. A combined epidemiologic and metabolomic approach improves CKD prediction. J Am Soc Nephrol. 2013 Jul; 24(8):1330-8.View Related Profiles.

Larson, Martin
Yang, Qiong
Elmariah, Sammy
Ramachandran, Vasan

PMID: 23687356; PMCID: PMC3736702; DOI: 10.1681/ASN.2012101006;

Schnabel RB, Yin X, Larson MG, Yamamoto JF, Fontes JD, Kathiresan S, Rong J, Levy D, Keaney JF, Wang TJ, Murabito JM, Vasan RS, Benjamin EJ. Multiple inflammatory biomarkers in relation to cardiovascular events and mortality in the community. Arterioscler Thromb Vasc Biol. 2013 Jul; 33(7):1728-33.View Related Profiles.

Benjamin, Emelia
Murabito, Joanne
Larson, Martin
Ramachandran, Vasan
Yin, Xiaoyan

PMID: 23640499; PMCID: PMC3753537; DOI: 10.1161/ATVBAHA.112.301174;

Chami HA, Fontes JD, Vasan RS, Keaney JF, O'Connor GT, Larson MG, Benjamin EJ, Gottlieb DJ. Vascular inflammation and sleep disordered breathing in a community-based cohort. Sleep. 2013 May; 36(5):763-768C.View Related Profiles.

Benjamin, Emelia
O'Connor, George
Larson, Martin
Ramachandran, Vasan

PMID: 23633759; PMCID: PMC3622647; DOI: 10.5665/sleep.2644;

Ge Y, Cheng S, Larson MG, Ghorbani A, Martin RP, Klein RJ, O'Donnell CJ, Vasan RS, Shaw SY, Wang TJ, Cohen KS. Circulating CD31+ leukocyte frequency is associated with cardiovascular risk factors. Atherosclerosis. 2013 Jul; 229(1):228-33.View Related Profiles.

O'Donnell, Christopher
Larson, Martin
Ramachandran, Vasan

PMID: 23701996; DOI: 10.1016/j.atherosclerosis.2013.04.017;

Schnabel RB, Rienstra M, Sullivan LM, Sun JX, Moser CB, Levy D, Pencina MJ, Fontes JD, Magnani JW, McManus DD, Lubitz SA, Tadros TM, Wang TJ, Ellinor PT, Vasan RS, Benjamin EJ. Risk assessment for incident heart failure in individuals with atrial fibrillation. Eur J Heart Fail. 2013 Aug; 15(8):843-9.View Related Profiles.

Benjamin, Emelia
Sun, Fangui
Magnani, Jared
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Pencina, Michael
Ramachandran, Vasan

PMID: 23594831; PMCID: PMC3858114; DOI: 10.1093/eurjhf/hft041;

Xanthakis V, Vasan RS. Aldosterone and the risk of hypertension. Curr Hypertens Rep. 2013 Apr; 15(2):102-7.View Related Profiles.

Xanthakis, Vanessa
Ramachandran, Vasan

PMID: 23378101; PMCID: PMC3619380; DOI: 10.1007/s11906-013-0330-y;

Haring R, Teng Z, Xanthakis V, Coviello A, Sullivan L, Bhasin S, Murabito JM, Wallaschofski H, Vasan RS. Association of sex steroids, gonadotrophins, and their trajectories with clinical cardiovascular disease and all-cause mortality in elderly men from the Framingham Heart Study. Clin Endocrinol (Oxf). 2013 Apr; 78(4):629-34.View Related Profiles.

Coviello, Andrea
Murabito, Joanne
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Bhasin, Shalender
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Ramachandran, Vasan

PMID: 22901104; PMCID: PMC4161203 ; DOI: 10.1111/cen.12013;

Lieb W, Jansen H, Loley C, Pencina MJ, Nelson CP, Newton-Cheh C, Kathiresan S, Reilly MP, Assimes TL, Boerwinkle E, Hall AS, Hengstenberg C, Laaksonen R, McPherson R, Thorsteinsdottir U, Ziegler A, Peters A, Thompson JR, König IR, Erdmann J, Samani NJ, Vasan RS, Schunkert H, Assimes TL, Deloukas P, Erdmann J, Holm H, Kathiresan S, König IR, McPherson R, Reilly MP, Roberts R, Samani NJ, Schunkert H, Stewart AF. Genetic predisposition to higher blood pressure increases coronary artery disease risk. Hypertension. 2013 May; 61(5):995-1001.View Related Profiles.

Pencina, Michael
Ramachandran, Vasan

PMID: 23478099; DOI: 10.1161/HYPERTENSIONAHA.111.00275;

Kraigher-Krainer E, Lyass A, Massaro JM, Lee DS, Ho JE, Levy D, Kannel WB, Vasan RS. Association of physical activity and heart failure with preserved vs. reduced ejection fraction in the elderly: the Framingham Heart Study. Eur J Heart Fail. 2013 Jul; 15(7):742-6.View Related Profiles.

Ho, Jennifer
Massaro, Joseph
Ramachandran, Vasan

PMID: 23435761; PMCID: PMC3857918; DOI: 10.1093/eurjhf/hft025;

Robins SJ, Lyass A, Brocia RW, Massaro JM, Vasan RS. Plasma lipid transfer proteins and cardiovascular disease. The Framingham Heart Study. Atherosclerosis. 2013 May; 228(1):230-6.View Related Profiles.

Massaro, Joseph
Robins, Sander
Ramachandran, Vasan

PMID: 23477743; PMCID: PMC3692011; DOI: 10.1016/j.atherosclerosis.2013.01.046;

Fontes JD, Yamamoto JF, Larson MG, Wang N, Dallmeier D, Rienstra M, Schnabel RB, Vasan RS, Keaney JF, Benjamin EJ. Clinical correlates of change in inflammatory biomarkers: The Framingham Heart Study. Atherosclerosis. 2013 May; 228(1):217-23.View Related Profiles.

Dallmeier Rojas, Dhayana
Benjamin, Emelia
Larson, Martin
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PMID: 23489346; PMCID: PMC3650714; DOI: 10.1016/j.atherosclerosis.2013.01.019;

Ho JE, Larson MG, Vasan RS, Ghorbani A, Cheng S, Rhee EP, Florez JC, Clish CB, Gerszten RE, Wang TJ. Metabolite profiles during oral glucose challenge. Diabetes. 2013 Aug; 62(8):2689-98.View Related Profiles.

Ho, Jennifer
Larson, Martin
Ramachandran, Vasan

PMID: 23382451; PMCID: PMC3717862; DOI: 10.2337/db12-0754;

Lam CS, Gona P, Larson MG, Aragam J, Lee DS, Mitchell GF, Levy D, Cheng S, Benjamin EJ, Vasan RS. Aortic root remodeling and risk of heart failure in the Framingham Heart study. JACC Heart Fail. 2013 Feb; 1(1):79-83.View Related Profiles.

Benjamin, Emelia
Aragam, Jayashri
Larson, Martin
Ramachandran, Vasan

PMID: 23998002; PMCID: PMC3755769

Jacques PF, Lyass A, Massaro JM, Vasan RS, D'Agostino RB. Relationship of lycopene intake and consumption of tomato products to incident CVD. Br J Nutr. 2013 Aug 28; 110(3):545-51.View Related Profiles.

Massaro, Joseph
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 23317928; PMCID: PMC3710301; DOI: 10.1017/S0007114512005417;

Ganesh SK, Tragante V, Guo W, Guo Y, Lanktree MB, Smith EN, Johnson T, Castillo BA, Barnard J, Baumert J, Chang YP, Elbers CC, Farrall M, Fischer ME, Franceschini N, Gaunt TR, Gho JM, Gieger C, Gong Y, Isaacs A, Kleber ME, Mateo Leach I, McDonough CW, Meijs MF, Mellander O, Molony CM, Nolte IM, Padmanabhan S, Price TS, Rajagopalan R, Shaffer J, Shah S, Shen H, Soranzo N, van der Most PJ, Van Iperen EP, Van Setten J, Van Setten JA, Vonk JM, Zhang L, Beitelshees AL, Berenson GS, Bhatt DL, Boer JM, Boerwinkle E, Burkley B, Burt A, Chakravarti A, Chen W, Cooper-Dehoff RM, Curtis SP, Dreisbach A, Duggan D, Ehret GB, Fabsitz RR, Fornage M, Fox E, Furlong CE, Gansevoort RT, Hofker MH, Hovingh GK, Kirkland SA, Kottke-Marchant K, Kutlar A, Lacroix AZ, Langaee TY, Li YR, Lin H, Liu K, Maiwald S, Malik R, Murugesan G, Newton-Cheh C, O'Connell JR, Onland-Moret NC, Ouwehand WH, Palmas W, Penninx BW, Pepine CJ, Pettinger M, Polak JF, Ramachandran VS, Ranchalis J, Redline S, Ridker PM, Rose LM, Scharnag H, Schork NJ, Shimbo D, Shuldiner AR, Srinivasan SR, Stolk RP, Taylor HA, Thorand B, Trip MD, van Duijn CM, Verschuren WM, Wijmenga C, Winkelmann BR, Wyatt S, Young JH, Boehm BO, Caulfield MJ, Chasman DI, Davidson KW, Doevendans PA, Fitzgerald GA, Gums JG, Hakonarson H, Hillege HL, Illig T, Jarvik GP, Johnson JA, Kastelein JJ, Koenig W, März W, Mitchell BD, Murray SS, Oldehinkel AJ, Rader DJ, Reilly MP, Reiner AP, Schadt EE, Silverstein RL, Snieder H, Stanton AV, Uitterlinden AG, van der Harst P, van der Schouw YT, Samani NJ, Johnson AD, Munroe PB, de Bakker PI, Zhu X, Levy D, Keating BJ, Asselbergs FW. Loci influencing blood pressure identified using a cardiovascular gene-centric array. Hum Mol Genet. 2013 Apr 15; 22(8):1663-78.View Related Profiles.

Lin, Honghuang
Polak, Joseph
Ramachandran, Vasan

PMID: 23303523; PMCID: PMC3657476; DOI: 10.1093/hmg/dds555;

Cohen KS, Cheng S, Larson MG, Cupples LA, McCabe EL, Wang YA, Ngwa JS, Martin RP, Klein RJ, Hashmi B, Ge Y, O'Donnell CJ, Vasan RS, Shaw SY, Wang TJ. Circulating CD34(+) progenitor cell frequency is associated with clinical and genetic factors. Blood. 2013 Feb 21; 121(8):e50-6.View Related Profiles.

O'Donnell, Christopher
Cupples, L
Larson, Martin
Ramachandran, Vasan

PMID: 23287867; PMCID: PMC3578962; DOI: 10.1182/blood-2012-05-424846;

Kaess BM, Vasan RS, Mitchell GF. Aortic stiffness and incident hypertension--reply. JAMA. 2013 Jan 2; 309(1):30.View Related Profiles.

Kaess, Bernhard
Ramachandran, Vasan

PMID: 23280214

Preis SR, Pencina MJ, D'Agostino RB, Meigs JB, Vasan RS, Fox CS. Neck circumference and the development of cardiovascular disease risk factors in the Framingham Heart Study. Diabetes Care. 2013 Jan; 36(1):e3.View Related Profiles.

Pencina, Michael
D'Agostino, Ralph
Preis, Sarah
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PMID: 23264305; PMCID: PMC3526209; DOI: 10.2337/dc12-0738;

Glazer NL, Lyass A, Esliger DW, Blease SJ, Freedson PS, Massaro JM, Murabito JM, Vasan RS. Sustained and shorter bouts of physical activity are related to cardiovascular health. Med Sci Sports Exerc. 2013 Jan; 45(1):109-15.View Related Profiles.

Murabito, Joanne
Massaro, Joseph
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PMID: 22895372; PMCID: PMC4166425 ; DOI: 10.1249/MSS.0b013e31826beae5;

Berry SD, Ramachandran VS, Cawthon PM, Gona P, McLean RR, Cupples LA, Kiel DP. Procollagen type III N-terminal peptide (P3NP) and lean mass: a cross-sectional study. J Frailty Aging. 2013; 2(3):129-34.View Related Profiles.

Cupples, L
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PMID: 24244927; PMCID: PMC3828748

Fox ER, Musani SK, Barbalic M, Lin H, Yu B, Ogunyankin KO, Smith NL, Kutlar A, Glazer NL, Post WS, Paltoo DN, Dries DL, Farlow DN, Duarte CW, Kardia SL, Meyers KJ, Sun YV, Arnett DK, Patki AA, Sha J, Cui X, Samdarshi TE, Penman AD, Bibbins-Domingo K, Bužková P, Benjamin EJ, Bluemke DA, Morrison AC, Heiss G, Carr JJ, Tracy RP, Mosley TH, Taylor HA, Psaty BM, Heckbert SR, Cappola TP, Vasan RS. Genome-wide association study of cardiac structure and systolic function in African Americans: the Candidate Gene Association Resource (CARe) study. Circ Cardiovasc Genet. 2013 Feb; 6(1):37-46.View Related Profiles.

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Ho JE, Lyass A, Lee DS, Vasan RS, Kannel WB, Larson MG, Levy D. Predictors of new-onset heart failure: differences in preserved versus reduced ejection fraction. Circ Heart Fail. 2013 Mar; 6(2):279-86.View Related Profiles.

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Chen MH, Huang J, Chen WM, Larson MG, Fox CS, Vasan RS, Seshadri S, O'Donnell CJ, Yang Q. Using family-based imputation in genome-wide association studies with large complex pedigrees: the Framingham Heart Study. PLoS One. 2012; 7(12):e51589.View Related Profiles.

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Franzini M, Fornaciari I, Rong J, Larson MG, Passino C, Emdin M, Paolicchi A, Vasan RS. Correlates and reference limits of plasma gamma-glutamyltransferase fractions from the Framingham Heart Study. Clin Chim Acta. 2013 Feb 18; 417:19-25.View Related Profiles.

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PMID: 23247050; DOI: 10.1016/j.cca.2012.12.002;

Fox ER, Musani SK, Singh P, Bidulescu A, Nagarajarao HS, Samdarshi TE, Steffes MW, Wang TJ, Taylor HA, Vasan RS. Association of plasma B-type natriuretic peptide concentrations with longitudinal blood pressure tracking in African Americans: findings from the Jackson Heart Study. Hypertension. 2013 Jan; 61(1):48-54. PMID: 23184379; PMCID: PMC3521855

Khan AM, Lubitz SA, Sullivan LM, Sun JX, Levy D, Vasan RS, Magnani JW, Ellinor PT, Benjamin EJ, Wang TJ. Low serum magnesium and the development of atrial fibrillation in the community: the Framingham Heart Study. Circulation. 2013 Jan 1; 127(1):33-8.View Related Profiles.

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PMID: 23172839; PMCID: PMC3541701; DOI: 10.1161/CIRCULATIONAHA.111.082511;

Porter SA, Pedley A, Massaro JM, Vasan RS, Hoffmann U, Fox CS. Aminotransferase levels are associated with cardiometabolic risk above and beyond visceral fat and insulin resistance: the Framingham Heart Study. Arterioscler Thromb Vasc Biol. 2013 Jan; 33(1):139-46.View Related Profiles.

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PMID: 23162012; PMCID: PMC3593729; DOI: 10.1161/ATVBAHA.112.300075;

Sinner MF, Wang N, Fox CS, Fontes JD, Rienstra M, Magnani JW, Vasan RS, Calderwood AH, Pencina M, Sullivan LM, Ellinor PT, Benjamin EJ. Relation of circulating liver transaminase concentrations to risk of new-onset atrial fibrillation. Am J Cardiol. 2013 Jan 15; 111(2):219-24.View Related Profiles.

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PMID: 23127690; PMCID: PMC3538882; DOI: 10.1016/j.amjcard.2012.09.021;

Cheng S, Xanthakis V, Sullivan LM, Vasan RS. Blood pressure tracking over the adult life course: patterns and correlates in the Framingham heart study. Hypertension. 2012 Dec; 60(6):1393-9.View Related Profiles.

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PMID: 23108660; PMCID: PMC3499677; DOI: 10.1161/HYPERTENSIONAHA.112.201780;

Jasuja GK, Travison TG, Davda M, Murabito JM, Basaria S, Zhang A, Kushnir MM, Rockwood AL, Meikle W, Pencina MJ, Coviello A, Rose AJ, D'Agostino R, Vasan RS, Bhasin S. Age trends in estradiol and estrone levels measured using liquid chromatography tandem mass spectrometry in community-dwelling men of the Framingham Heart Study. J Gerontol A Biol Sci Med Sci. 2013 Jun; 68(6):733-40.View Related Profiles.

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Coglianese EE, Larson MG, Vasan RS, Ho JE, Ghorbani A, McCabe EL, Cheng S, Fradley MG, Kretschman D, Gao W, O'Connor G, Wang TJ, Januzzi JL. Distribution and clinical correlates of the interleukin receptor family member soluble ST2 in the Framingham Heart Study. Clin Chem. 2012 Dec; 58(12):1673-81.View Related Profiles.

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PMID: 23065477; PMCID: PMC3557515; DOI: 10.1373/clinchem.2012.192153;

Kaptoge S, Di Angelantonio E, Pennells L, Wood AM, White IR, Gao P, Walker M, Thompson A, Sarwar N, Caslake M, Butterworth AS, Amouyel P, Assmann G, Bakker SJ, Barr EL, Barrett-Connor E, Benjamin EJ, Björkelund C, Brenner H, Brunner E, Clarke R, Cooper JA, Cremer P, Cushman M, Dagenais GR, D'Agostino RB, Dankner R, Davey-Smith G, Deeg D, Dekker JM, Engström G, Folsom AR, Fowkes FG, Gallacher J, Gaziano JM, Giampaoli S, Gillum RF, Hofman A, Howard BV, Ingelsson E, Iso H, Jørgensen T, Kiechl S, Kitamura A, Kiyohara Y, Koenig W, Kromhout D, Kuller LH, Lawlor DA, Meade TW, Nissinen A, Nordestgaard BG, Onat A, Panagiotakos DB, Psaty BM, Rodriguez B, Rosengren A, Salomaa V, Kauhanen J, Salonen JT, Shaffer JA, Shea S, Ford I, Stehouwer CD, Strandberg TE, Tipping RW, Tosetto A, Wassertheil-Smoller S, Wennberg P, Westendorp RG, Whincup PH, Wilhelmsen L, Woodward M, Lowe GD, Wareham NJ, Khaw KT, Sattar N, Packard CJ, Gudnason V, Ridker PM, Pepys MB, Thompson SG, Danesh J. C-reactive protein, fibrinogen, and cardiovascular disease prediction. N Engl J Med. 2012 Oct 4; 367(14):1310-20.View Related Profiles.

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PMID: 23034020; PMCID: PMC3714101; DOI: 10.1056/NEJMoa1107477;

Ho JE, Mahajan A, Chen MH, Larson MG, McCabe EL, Ghorbani A, Cheng S, Johnson AD, Lindgren CM, Kempf T, Lind L, Ingelsson E, Vasan RS, Januzzi J, Wollert KC, Morris AP, Wang TJ. Clinical and genetic correlates of growth differentiation factor 15 in the community. Clin Chem. 2012 Nov; 58(11):1582-91.View Related Profiles.

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Bick AG, Flannick J, Ito K, Cheng S, Vasan RS, Parfenov MG, Herman DS, DePalma SR, Gupta N, Gabriel SB, Funke BH, Rehm HL, Benjamin EJ, Aragam J, Taylor HA, Fox ER, Newton-Cheh C, Kathiresan S, O'Donnell CJ, Wilson JG, Altshuler DM, Hirschhorn JN, Seidman JG, Seidman C. Burden of rare sarcomere gene variants in the Framingham and Jackson Heart Study cohorts. Am J Hum Genet. 2012 Sep 7; 91(3):513-9.View Related Profiles.

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PMID: 22958901; PMCID: PMC3511985; DOI: 10.1016/j.ajhg.2012.07.017;

Kaess BM, Rong J, Larson MG, Hamburg NM, Vita JA, Levy D, Benjamin EJ, Vasan RS, Mitchell GF. Aortic stiffness, blood pressure progression, and incident hypertension. JAMA. 2012 Sep 5; 308(9):875-81.View Related Profiles.

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PMID: 22948697; PMCID: PMC3594687; DOI: 10.1001/2012.jama.10503;

Liu C, Yang Q, Hwang SJ, Sun F, Johnson AD, Shirihai OS, Vasan RS, Levy D, Schwartz F. Association of genetic variation in the mitochondrial genome with blood pressure and metabolic traits. Hypertension. 2012 Oct; 60(4):949-56.View Related Profiles.

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PMID: 22949535; PMCID: PMC3753106; DOI: 10.1161/HYPERTENSIONAHA.112.196519;

Xanthakis V, Vasan RS. Improving cardiovascular health in women & children around the world. Indian J Med Res. 2012 Sep; 136(3):359-61.View Related Profiles.

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Ho JE, Liu C, Lyass A, Courchesne P, Pencina MJ, Vasan RS, Larson MG, Levy D. Galectin-3, a marker of cardiac fibrosis, predicts incident heart failure in the community. J Am Coll Cardiol. 2012 Oct 2; 60(14):1249-56.View Related Profiles.

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PMID: 22939561; PMCID: PMC3512095; DOI: 10.1016/j.jacc.2012.04.053;

Wang TJ, Wollert KC, Larson MG, Coglianese E, McCabe EL, Cheng S, Ho JE, Fradley MG, Ghorbani A, Xanthakis V, Kempf T, Benjamin EJ, Levy D, Vasan RS, Januzzi JL. Prognostic utility of novel biomarkers of cardiovascular stress: the Framingham Heart Study. Circulation. 2012 Sep 25; 126(13):1596-604.View Related Profiles.

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Kaess BM, Enserro DM, McManus DD, Xanthakis V, Chen MH, Sullivan LM, Ingram C, O'Donnell CJ, Keaney JF, Vasan RS, Glazer NL. Cardiometabolic correlates and heritability of fetuin-A, retinol-binding protein 4, and fatty-acid binding protein 4 in the Framingham Heart Study. J Clin Endocrinol Metab. 2012 Oct; 97(10):E1943-7.View Related Profiles.

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PMID: 22855337; PMCID: PMC3674297; DOI: 10.1210/jc.2012-1458;

Haring R, Friedrich N, Völzke H, Vasan RS, Felix SB, Dörr M, Meyer zu Schwabedissen HE, Nauck M, Wallaschofski H. Positive association of serum prolactin concentrations with all-cause and cardiovascular mortality. Eur Heart J. 2014 May; 35(18):1215-21. PMID: 22843444; DOI: 10.1093/eurheartj/ehs233;

Adult height and the risk of cause-specific death and vascular morbidity in 1 million people: individual participant meta-analysis. Int J Epidemiol. 2012 Oct; 41(5):1419-33. PMID: 22825588; PMCID: PMC3465767

Coviello AD, Haring R, Wellons M, Vaidya D, Lehtimäki T, Keildson S, Lunetta KL, He C, Fornage M, Lagou V, Mangino M, Onland-Moret NC, Chen B, Eriksson J, Garcia M, Liu YM, Koster A, Lohman K, Lyytikäinen LP, Petersen AK, Prescott J, Stolk L, Vandenput L, Wood AR, Zhuang WV, Ruokonen A, Hartikainen AL, Pouta A, Bandinelli S, Biffar R, Brabant G, Cox DG, Chen Y, Cummings S, Ferrucci L, Gunter MJ, Hankinson SE, Martikainen H, Hofman A, Homuth G, Illig T, Jansson JO, Johnson AD, Karasik D, Karlsson M, Kettunen J, Kiel DP, Kraft P, Liu J, Ljunggren Ö, Lorentzon M, Maggio M, Markus MR, Mellström D, Miljkovic I, Mirel D, Nelson S, Morin Papunen L, Peeters PH, Prokopenko I, Raffel L, Reincke M, Reiner AP, Rexrode K, Rivadeneira F, Schwartz SM, Siscovick D, Soranzo N, Stöckl D, Tworoger S, Uitterlinden AG, van Gils CH, Vasan RS, Wichmann HE, Zhai G, Bhasin S, Bidlingmaier M, Chanock SJ, De Vivo I, Harris TB, Hunter DJ, Kähönen M, Liu S, Ouyang P, Spector TD, van der Schouw YT, Viikari J, Wallaschofski H, McCarthy MI, Frayling TM, Murray A, Franks S, Järvelin MR, de Jong FH, Raitakari O, Teumer A, Ohlsson C, Murabito JM, Perry JR. A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation. PLoS Genet. 2012; 8(7):e1002805.View Related Profiles.

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PMID: 22829776; PMCID: PMC3400553; DOI: 10.1371/journal.pgen.1002805;

Dallmeier D, Larson MG, Vasan RS, Keaney JF, Fontes JD, Meigs JB, Fox CS, Benjamin EJ. Metabolic syndrome and inflammatory biomarkers: a community-based cross-sectional study at the Framingham Heart Study. Diabetol Metab Syndr. 2012; 4(1):28.View Related Profiles.

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PMID: 22716219; PMCID: PMC3547735; DOI: 10.1186/1758-5996-4-28;

Harris WS, Pottala JV, Lacey SM, Vasan RS, Larson MG, Robins SJ. Clinical correlates and heritability of erythrocyte eicosapentaenoic and docosahexaenoic acid content in the Framingham Heart Study. Atherosclerosis. 2012 Dec; 225(2):425-31.View Related Profiles.

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PMID: 22727409; PMCID: PMC3593234; DOI: 10.1016/j.atherosclerosis.2012.05.030;

Haring R, Xanthakis V, Coviello A, Sullivan L, Bhasin S, Wallaschofski H, Murabito JM, Vasan RS. Clinical correlates of sex steroids and gonadotropins in men over the late adulthood: the Framingham Heart Study. Int J Androl. 2012 Dec; 35(6):775-82.View Related Profiles.

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PMID: 22640232; PMCID: PMC3434249; DOI: 10.1111/j.1365-2605.2012.01285.x;

Harris WS, Pottala JV, Vasan RS, Larson MG, Robins SJ. Changes in erythrocyte membrane trans and marine fatty acids between 1999 and 2006 in older Americans. J Nutr. 2012 Jul; 142(7):1297-303.View Related Profiles.

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PMID: 22623386; PMCID: PMC3374668; DOI: 10.3945/jn.112.158295;

Thanassoulis G, Lyass A, Benjamin EJ, Larson MG, Vita JA, Levy D, Hamburg NM, Widlansky ME, O'Donnell CJ, Mitchell GF, Vasan RS. Relations of exercise blood pressure response to cardiovascular risk factors and vascular function in the Framingham Heart Study. Circulation. 2012 Jun 12; 125(23):2836-43.View Related Profiles.

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PMID: 22572915; PMCID: PMC3636551; DOI: 10.1161/CIRCULATIONAHA.111.063933;

Ho JE, Gona P, Pencina MJ, Tu JV, Austin PC, Vasan RS, Kannel WB, D'Agostino RB, Lee DS, Levy D. Discriminating clinical features of heart failure with preserved vs. reduced ejection fraction in the community. Eur Heart J. 2012 Jul; 33(14):1734-41.View Related Profiles.

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PMID: 22507977; PMCID: PMC3530391; DOI: 10.1093/eurheartj/ehs070;

Cheng S, Rhee EP, Larson MG, Lewis GD, McCabe EL, Shen D, Palma MJ, Roberts LD, Dejam A, Souza AL, Deik AA, Magnusson M, Fox CS, O'Donnell CJ, Vasan RS, Melander O, Clish CB, Gerszten RE, Wang TJ. Metabolite profiling identifies pathways associated with metabolic risk in humans. Circulation. 2012 May 8; 125(18):2222-31.View Related Profiles.

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PMID: 22496159; PMCID: PMC3376658; DOI: 10.1161/CIRCULATIONAHA.111.067827;

O'Seaghdha CM, Hwang SJ, Vasan RS, Larson MG, Hoffmann U, Wang TJ, Fox CS. Correlation of renin angiotensin and aldosterone system activity with subcutaneous and visceral adiposity: the framingham heart study. BMC Endocr Disord. 2012; 12:3.View Related Profiles.

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PMID: 22475205; PMCID: PMC3352034; DOI: 10.1186/1472-6823-12-3;

Pikula A, Beiser AS, DeCarli C, Himali JJ, Debette S, Au R, Selhub J, Toffler GH, Wang TJ, Meigs JB, Kelly-Hayes M, Kase CS, Wolf PA, Vasan RS, Seshadri S. Multiple biomarkers and risk of clinical and subclinical vascular brain injury: the Framingham Offspring Study. Circulation. 2012 May 1; 125(17):2100-7.View Related Profiles.

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PMID: 22456473; PMCID: PMC3427730; DOI: 10.1161/CIRCULATIONAHA.110.989145;

Tan ZS, Harris WS, Beiser AS, Au R, Himali JJ, Debette S, Pikula A, Decarli C, Wolf PA, Vasan RS, Robins SJ, Seshadri S. Red blood cell ?-3 fatty acid levels and markers of accelerated brain aging. Neurology. 2012 Feb 28; 78(9):658-64.View Related Profiles.

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PMID: 22371413; PMCID: PMC3286229; DOI: 10.1212/WNL.0b013e318249f6a9;

Zachariah JP, Xanthakis V, Larson MG, Vita JA, Sullivan LM, Smith HM, Safa R, Peng X, Hamburg N, Levy D, Sawyer DB, Mitchell GF, Vasan RS. Circulating vascular growth factors and central hemodynamic load in the community. Hypertension. 2012 Apr; 59(4):773-9.View Related Profiles.

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PMID: 22371357; PMCID: PMC3336212; DOI: 10.1161/HYPERTENSIONAHA.111.179242;

Haring R, Völzke H, Vasan RS, Felix SB, Nauck M, Dörr M, Wallaschofski H. Sex-specific associations of serum prolactin concentrations with cardiac remodeling: longitudinal results from the Study of Health Pomerania (SHIP). Atherosclerosis. 2012 Apr; 221(2):570-6. PMID: 22293228; DOI: 10.1016/j.atherosclerosis.2012.01.017;

Kaess BM, Pedley A, Massaro JM, Larson MG, Corsini E, Hoffmann U, Smith HM, Sawyer DB, Vasan RS, Fox CS. Relation of vascular growth factors with CT-derived measures of body fat distribution: the Framingham Heart Study. J Clin Endocrinol Metab. 2012 Mar; 97(3):987-94.View Related Profiles.

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PMID: 22170711; PMCID: PMC3319207; DOI: 10.1210/jc.2011-2310;

Dhingra R, Vasan RS. Age as a risk factor. Med Clin North Am. 2012 Jan; 96(1):87-91. PMID: 22391253; PMCID: PMC3297980

Rienstra M, Sun JX, Lubitz SA, Frankel DS, Vasan RS, Levy D, Magnani JW, Sullivan LM, Meigs JB, Ellinor PT, Benjamin EJ. Plasma resistin, adiponectin, and risk of incident atrial fibrillation: the Framingham Offspring Study. Am Heart J. 2012 Jan; 163(1):119-124.e1.View Related Profiles.

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PMID: 22172445; PMCID: PMC3375331; DOI: 10.1016/j.ahj.2011.09.029;

Cheng S, Vasan RS. Advances in the epidemiology of heart failure and left ventricular remodeling. Circulation. 2011 Nov 15; 124(20):e516-9. PMID: 22083151; PMCID: PMC3621875; DOI: 10.1161/CIRCULATIONAHA.111.070235;

Mitchell GF, Verwoert GC, Tarasov KV, Isaacs A, Smith AV, Yasmin, Rietzschel ER, Tanaka T, Liu Y, Parsa A, Najjar SS, O'Shaughnessy KM, Sigurdsson S, De Buyzere ML, Larson MG, Sie MP, Andrews JS, Post WS, Mattace-Raso FU, McEniery CM, Eiriksdottir G, Segers P, Vasan RS, van Rijn MJ, Howard TD, McArdle PF, Dehghan A, Jewell ES, Newhouse SJ, Bekaert S, Hamburg NM, Newman AB, Hofman A, Scuteri A, De Bacquer D, Ikram MA, Psaty BM, Fuchsberger C, Olden M, Wain LV, Elliott P, Smith NL, Felix JF, Erdmann J, Vita JA, Sutton-Tyrrell K, Sijbrands EJ, Sanna S, Launer LJ, De Meyer T, Johnson AD, Schut AF, Herrington DM, Rivadeneira F, Uda M, Wilkinson IB, Aspelund T, Gillebert TC, Van Bortel L, Benjamin EJ, Oostra BA, Ding J, Gibson Q, Uitterlinden AG, Abecasis GR, Cockcroft JR, Gudnason V, De Backer GG, Ferrucci L, Harris TB, Shuldiner AR, van Duijn CM, Levy D, Lakatta EG, Witteman JC. Common genetic variation in the 3'-BCL11B gene desert is associated with carotid-femoral pulse wave velocity and excess cardiovascular disease risk: the AortaGen Consortium. Circ Cardiovasc Genet. 2012 Feb 1; 5(1):81-90.View Related Profiles.

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PMID: 22068335; PMCID: PMC3288392; DOI: 10.1161/CIRCGENETICS.111.959817;

Lüneburg N, Xanthakis V, Schwedhelm E, Sullivan LM, Maas R, Anderssohn M, Riederer U, Glazer NL, Vasan RS, Böger RH. Reference intervals for plasma L-arginine and the L-arginine:asymmetric dimethylarginine ratio in the Framingham Offspring Cohort. J Nutr. 2011 Dec; 141(12):2186-90.View Related Profiles.

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PMID: 22031661; PMCID: PMC3223876; DOI: 10.3945/jn.111.148197;

Cheng S, Wang N, Larson MG, Palmisano JN, Mitchell GF, Benjamin EJ, Vasan RS, Levy D, McCabe EL, Vita JA, Wang TJ, Shaw SY, Cohen KS, Hamburg NM. Circulating angiogenic cell populations, vascular function, and arterial stiffness. Atherosclerosis. 2012 Jan; 220(1):145-50.View Related Profiles.

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PMID: 22093724; PMCID: PMC3277804; DOI: 10.1016/j.atherosclerosis.2011.10.015;

Chambers JC, Zhang W, Sehmi J, Li X, Wass MN, Van der Harst P, Holm H, Sanna S, Kavousi M, Baumeister SE, Coin LJ, Deng G, Gieger C, Heard-Costa NL, Hottenga JJ, Kühnel B, Kumar V, Lagou V, Liang L, Luan J, Vidal PM, Mateo Leach I, O'Reilly PF, Peden JF, Rahmioglu N, Soininen P, Speliotes EK, Yuan X, Thorleifsson G, Alizadeh BZ, Atwood LD, Borecki IB, Brown MJ, Charoen P, Cucca F, Das D, de Geus EJ, Dixon AL, Döring A, Ehret G, Eyjolfsson GI, Farrall M, Forouhi NG, Friedrich N, Goessling W, Gudbjartsson DF, Harris TB, Hartikainen AL, Heath S, Hirschfield GM, Hofman A, Homuth G, Hyppönen E, Janssen HL, Johnson T, Kangas AJ, Kema IP, Kühn JP, Lai S, Lathrop M, Lerch MM, Li Y, Liang TJ, Lin JP, Loos RJ, Martin NG, Moffatt MF, Montgomery GW, Munroe PB, Musunuru K, Nakamura Y, O'Donnell CJ, Olafsson I, Penninx BW, Pouta A, Prins BP, Prokopenko I, Puls R, Ruokonen A, Savolainen MJ, Schlessinger D, Schouten JN, Seedorf U, Sen-Chowdhry S, Siminovitch KA, Smit JH, Spector TD, Tan W, Teslovich TM, Tukiainen T, Uitterlinden AG, Van der Klauw MM, Vasan RS, Wallace C, Wallaschofski H, Wichmann HE, Willemsen G, Würtz P, Xu C, Yerges-Armstrong LM, Abecasis GR, Ahmadi KR, Boomsma DI, Caulfield M, Cookson WO, van Duijn CM, Froguel P, Matsuda K, McCarthy MI, Meisinger C, Mooser V, Pietiläinen KH, Schumann G, Snieder H, Sternberg MJ, Stolk RP, Thomas HC, Thorsteinsdottir U, Uda M, Waeber G, Wareham NJ, Waterworth DM, Watkins H, Whitfield JB, Witteman JC, Wolffenbuttel BH, Fox CS, Ala-Korpela M, Stefansson K, Vollenweider P, Völzke H, Schadt EE, Scott J, Järvelin MR, Elliott P, Kooner JS. Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. Nat Genet. 2011 Nov; 43(11):1131-8.View Related Profiles.

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Ramachandran, Vasan

PMID: 22001757; PMCID: PMC3482372; DOI: 10.1038/ng.970;

Grallert H, Dupuis J, Bis JC, Dehghan A, Barbalic M, Baumert J, Lu C, Smith NL, Uitterlinden AG, Roberts R, Khuseyinova N, Schnabel RB, Rice KM, Rivadeneira F, Hoogeveen RC, Fontes JD, Meisinger C, Keaney JF, Lemaitre R, Aulchenko YS, Vasan RS, Ellis S, Hazen SL, van Duijn CM, Nelson JJ, März W, Schunkert H, McPherson RM, Stirnadel-Farrant HA, Psaty BM, Gieger C, Siscovick D, Hofman A, Illig T, Cushman M, Yamamoto JF, Rotter JI, Larson MG, Stewart AF, Boerwinkle E, Witteman JC, Tracy RP, Koenig W, Benjamin EJ, Ballantyne CM. Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies. Eur Heart J. 2012 Jan; 33(2):238-51.View Related Profiles.

Benjamin, Emelia
Dupuis, Josee
Larson, Martin
Ramachandran, Vasan

PMID: 22003152; PMCID: PMC3258449; DOI: 10.1093/eurheartj/ehr372;

Dhingra R, Vasan RS. Diabetes and the risk of heart failure. Heart Fail Clin. 2012 Jan; 8(1):125-33. PMID: 22108732; PMCID: PMC3223386; DOI: 10.1016/j.hfc.2011.08.008;

Fontes JD, Lyass A, Massaro JM, Rienstra M, Dallmeier D, Schnabel RB, Wang TJ, Vasan RS, Lubitz SA, Magnani JW, Levy D, Ellinor PT, Fox CS, Benjamin EJ. Insulin resistance and atrial fibrillation (from the Framingham Heart Study). Am J Cardiol. 2012 Jan 1; 109(1):87-90.View Related Profiles.

Dallmeier Rojas, Dhayana
Benjamin, Emelia
Magnani, Jared
Massaro, Joseph
Ramachandran, Vasan

PMID: 21996140; PMCID: PMC3242834; DOI: 10.1016/j.amjcard.2011.08.008;

Coglianese EE, Qureshi MM, Vasan RS, Wang TJ, Moore LL. Usefulness of the blood hematocrit level to predict development of heart failure in a community. Am J Cardiol. 2012 Jan 15; 109(2):241-5.View Related Profiles.

Moore, Lynn
Qureshi, Muhammad
Ramachandran, Vasan

PMID: 21996141; PMCID: PMC3663594; DOI: 10.1016/j.amjcard.2011.08.037;

Ohlsson C, Wallaschofski H, Lunetta KL, Stolk L, Perry JR, Koster A, Petersen AK, Eriksson J, Lehtimäki T, Huhtaniemi IT, Hammond GL, Maggio M, Coviello AD, Ferrucci L, Heier M, Hofman A, Holliday KL, Jansson JO, Kähönen M, Karasik D, Karlsson MK, Kiel DP, Liu Y, Ljunggren O, Lorentzon M, Lyytikäinen LP, Meitinger T, Mellström D, Melzer D, Miljkovic I, Nauck M, Nilsson M, Penninx B, Pye SR, Vasan RS, Reincke M, Rivadeneira F, Tajar A, Teumer A, Uitterlinden AG, Ulloor J, Viikari J, Völker U, Völzke H, Wichmann HE, Wu TS, Zhuang WV, Ziv E, Wu FC, Raitakari O, Eriksson A, Bidlingmaier M, Harris TB, Murray A, de Jong FH, Murabito JM, Bhasin S, Vandenput L, Haring R. Genetic determinants of serum testosterone concentrations in men. PLoS Genet. 2011 Oct; 7(10):e1002313.View Related Profiles.

Coviello, Andrea
Ulloor, Jagadish
Murabito, Joanne
Lunetta, Kathryn
Bhasin, Shalender
Ramachandran, Vasan

PMID: 21998597; PMCID: PMC3188559; DOI: 10.1371/journal.pgen.1002313;

Large-scale gene-centric analysis identifies novel variants for coronary artery disease. PLoS Genet. 2011 Sep; 7(9):e1002260.View Related Profiles.

Cupples, L
Ramachandran, Vasan

PMID: 21966275; PMCID: PMC3178591; DOI: 10.1371/journal.pgen.1002260;

Haring R, Travison TG, Bhasin S, Vasan RS, Wallaschofski H, Davda MN, Coviello A, Murabito JM. Relation between sex hormone concentrations, peripheral arterial disease, and change in ankle-brachial index: findings from the Framingham Heart Study. J Clin Endocrinol Metab. 2011 Dec; 96(12):3724-32.View Related Profiles.

Coviello, Andrea
Murabito, Joanne
Bhasin, Shalender
Travison, Thomas
Ramachandran, Vasan

PMID: 21937625; PMCID: PMC3232625; DOI: 10.1210/jc.2011-1068;

Bhasin S, Jasjua GK, Pencina M, D'Agostino R, Coviello AD, Vasan RS, Travison TG. Sex hormone-binding globulin, but not testosterone, is associated prospectively and independently with incident metabolic syndrome in men: the framingham heart study. Diabetes Care. 2011 Nov; 34(11):2464-70.View Related Profiles.

Coviello, Andrea
Pencina, Michael
D'Agostino, Ralph
Bhasin, Shalender
Travison, Thomas
Ramachandran, Vasan

PMID: 21926281; PMCID: PMC3198304; DOI: 10.2337/dc11-0888;

Wain LV, Verwoert GC, O'Reilly PF, Shi G, Johnson T, Johnson AD, Bochud M, Rice KM, Henneman P, Smith AV, Ehret GB, Amin N, Larson MG, Mooser V, Hadley D, Dörr M, Bis JC, Aspelund T, Esko T, Janssens AC, Zhao JH, Heath S, Laan M, Fu J, Pistis G, Luan J, Arora P, Lucas G, Pirastu N, Pichler I, Jackson AU, Webster RJ, Zhang F, Peden JF, Schmidt H, Tanaka T, Campbell H, Igl W, Milaneschi Y, Hottenga JJ, Vitart V, Chasman DI, Trompet S, Bragg-Gresham JL, Alizadeh BZ, Chambers JC, Guo X, Lehtimäki T, Kühnel B, Lopez LM, Polašek O, Boban M, Nelson CP, Morrison AC, Pihur V, Ganesh SK, Hofman A, Kundu S, Mattace-Raso FU, Rivadeneira F, Sijbrands EJ, Uitterlinden AG, Hwang SJ, Vasan RS, Wang TJ, Bergmann S, Vollenweider P, Waeber G, Laitinen J, Pouta A, Zitting P, McArdle WL, Kroemer HK, Völker U, Völzke H, Glazer NL, Taylor KD, Harris TB, Alavere H, Haller T, Keis A, Tammesoo ML, Aulchenko Y, Barroso I, Khaw KT, Galan P, Hercberg S, Lathrop M, Eyheramendy S, Org E, Sõber S, Lu X, Nolte IM, Penninx BW, Corre T, Masciullo C, Sala C, Groop L, Voight BF, Melander O, O'Donnell CJ, Salomaa V, d'Adamo AP, Fabretto A, Faletra F, Ulivi S, Del Greco F, Facheris M, Collins FS, Bergman RN, Beilby JP, Hung J, Musk AW, Mangino M, Shin SY, Soranzo N, Watkins H, Goel A, Hamsten A, Gider P, Loitfelder M, Zeginigg M, Hernandez D, Najjar SS, Navarro P, Wild SH, Corsi AM, Singleton A, de Geus EJ, Willemsen G, Parker AN, Rose LM, Buckley B, Stott D, Orru M, Uda M, van der Klauw MM, Zhang W, Li X, Scott J, Chen YD, Burke GL, Kähönen M, Viikari J, Döring A, Meitinger T, Davies G, Starr JM, Emilsson V, Plump A, Lindeman JH, Hoen PA, König IR, Felix JF, Clarke R, Hopewell JC, Ongen H, Breteler M, Debette S, Destefano AL, Fornage M, Mitchell GF, Smith NL, Holm H, Stefansson K, Thorleifsson G, Thorsteinsdottir U, Samani NJ, Preuss M, Rudan I, Hayward C, Deary IJ, Wichmann HE, Raitakari OT, Palmas W, Kooner JS, Stolk RP, Jukema JW, Wright AF, Boomsma DI, Bandinelli S, Gyllensten UB, Wilson JF, Ferrucci L, Schmidt R, Farrall M, Spector TD, Palmer LJ, Tuomilehto J, Pfeufer A, Gasparini P, Siscovick D, Altshuler D, Loos RJ, Toniolo D, Snieder H, Gieger C, Meneton P, Wareham NJ, Oostra BA, Metspalu A, Launer L, Rettig R, Strachan DP, Beckmann JS, Witteman JC, Erdmann J, van Dijk KW, Boerwinkle E, Boehnke M, Ridker PM, Jarvelin MR, Chakravarti A, Abecasis GR, Gudnason V, Newton-Cheh C, Levy D, Munroe PB, Psaty BM, Caulfield MJ, Rao DC, Tobin MD, Elliott P, van Duijn CM. Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet. 2011 Oct; 43(10):1005-11.View Related Profiles.

DeStefano, Anita
O'Donnell, Christopher
Larson, Martin
Hwang, Shih-Jen
Ramachandran, Vasan

PMID: 21909110; PMCID: PMC3445021; DOI: 10.1038/ng.922;

Ehret GB, Munroe PB, Rice KM, Bochud M, Johnson AD, Chasman DI, Smith AV, Tobin MD, Verwoert GC, Hwang SJ, Pihur V, Vollenweider P, O'Reilly PF, Amin N, Bragg-Gresham JL, Teumer A, Glazer NL, Launer L, Zhao JH, Aulchenko Y, Heath S, Sõber S, Parsa A, Luan J, Arora P, Dehghan A, Zhang F, Lucas G, Hicks AA, Jackson AU, Peden JF, Tanaka T, Wild SH, Rudan I, Igl W, Milaneschi Y, Parker AN, Fava C, Chambers JC, Fox ER, Kumari M, Go MJ, van der Harst P, Kao WH, Sjögren M, Vinay DG, Alexander M, Tabara Y, Shaw-Hawkins S, Whincup PH, Liu Y, Shi G, Kuusisto J, Tayo B, Seielstad M, Sim X, Nguyen KD, Lehtimäki T, Matullo G, Wu Y, Gaunt TR, Onland-Moret NC, Cooper MN, Platou CG, Org E, Hardy R, Dahgam S, Palmen J, Vitart V, Braund PS, Kuznetsova T, Uiterwaal CS, Adeyemo A, Palmas W, Campbell H, Ludwig B, Tomaszewski M, Tzoulaki I, Palmer ND, Aspelund T, Garcia M, Chang YP, O'Connell JR, Steinle NI, Grobbee DE, Arking DE, Kardia SL, Morrison AC, Hernandez D, Najjar S, McArdle WL, Hadley D, Brown MJ, Connell JM, Hingorani AD, Day IN, Lawlor DA, Beilby JP, Lawrence RW, Clarke R, Hopewell JC, Ongen H, Dreisbach AW, Li Y, Young JH, Bis JC, Kähönen M, Viikari J, Adair LS, Lee NR, Chen MH, Olden M, Pattaro C, Bolton JA, Köttgen A, Bergmann S, Mooser V, Chaturvedi N, Frayling TM, Islam M, Jafar TH, Erdmann J, Kulkarni SR, Bornstein SR, Grässler J, Groop L, Voight BF, Kettunen J, Howard P, Taylor A, Guarrera S, Ricceri F, Emilsson V, Plump A, Barroso I, Khaw KT, Weder AB, Hunt SC, Sun YV, Bergman RN, Collins FS, Bonnycastle LL, Scott LJ, Stringham HM, Peltonen L, Perola M, Vartiainen E, Brand SM, Staessen JA, Wang TJ, Burton PR, Soler Artigas M, Dong Y, Snieder H, Wang X, Zhu H, Lohman KK, Rudock ME, Heckbert SR, Smith NL, Wiggins KL, Doumatey A, Shriner D, Veldre G, Viigimaa M, Kinra S, Prabhakaran D, Tripathy V, Langefeld CD, Rosengren A, Thelle DS, Corsi AM, Singleton A, Forrester T, Hilton G, McKenzie CA, Salako T, Iwai N, Kita Y, Ogihara T, Ohkubo T, Okamura T, Ueshima H, Umemura S, Eyheramendy S, Meitinger T, Wichmann HE, Cho YS, Kim HL, Lee JY, Scott J, Sehmi JS, Z