Dr. Upadhyay is a board-certified nephrologist with academic interests in examining the interactions between metabolic and vascular diseases and CKD. He has conducted epidemiologic research in the Framingham Heart Study, led the evidence review team for the Kidney Disease Improving Global Outcomes (KDIGO) clinical practice guidelines on lipid management, participated in the evidence review teams for the KDIGO clinical practice guidelines on blood pressure and anemia management, and, currently, serves as one of the site investigators for the Kidney Precision Medicine Project (KPMP). At BU, in addition to directing the nephrology fellowship program, Dr. Upadhyay oversees research and EBM curriculum of the medicine residency program, and is a key faculty in BU’s NIH R38-funded research in residency program. He also has a special interest in hemodialysis systems and serves as a voting member of the Association for the Advancement of Medical Instrumentation’s Renal Disease and Detoxification Committee, the primary source of national and international consensus standards for hemodialysis technology and dialysis water sterilization processes. Dr. Upadhyay is the recipient of the 2021 Program Leadership Award from Boston Medical Center and the 2022 Robert Dawson Evans Special Recognition Teaching Award from the Department of Medicine.
Diversity, Equity, Inclusion and Accessibility
I strongly believe in the value of diversity and the importance of building inclusive and equitable work environment for our faculty and trainees. Both in internal medicine residency and nephrology, I have been a part of leadership that has made consistent strides in recruiting and supporting trainees and faculty from under-represented groups.
For patient care, consistent with the ethos of Boston Medical Center, I believe that access to high quality healthcare is a fundamental human right. Everyone, regardless of their background or financial resources, deserves a fair access to care, and an opportunity to participate in clinical trials and research.
Member
Boston University
Evans Center for Interdisciplinary Biomedical Research
Program Director
Boston University Chobanian & Avedisian School of Medicine
Nephrology Fellowship Program
Director, Scholarship and EBM
Boston University Chobanian & Avedisian School of Medicine
Internal Medicine Residency Program
Publications listed below are automatically derived from MEDLINE/PubMed and other
sources, which might result in incorrect or missing publications. Faculty can
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to make corrections and additions.
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Upadhyay A, Haider L. Mineralocorticoid Receptor Antagonists in Diabetic Kidney Disease: Clinical Evidence and Potential Adverse Events. Clinical Diabetes. American Diabetes Association. 2024; Online ahead of the print. View Publication
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Kamel MH, Mahmoud H, Zhen A, Liu J, Bielick CG, Mostaghim A, Lin N, Chitalia V, Ilori T, Waikar SS, Upadhyay A. End-stage kidney disease and COVID-19 in an urban safety-net hospital in Boston, Massachusetts. PLoS One. 2021; 16(6):e0252679.View Related Profiles. PMID: 34086775; PMCID: PMC8177422; DOI: 10.1371/journal.pone.0252679;
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Verma A, Patel AB, Upadhyay A, Waikar SS. CREDENCE: Significant Victory for Diabetic Kidney Disease. Trends Endocrinol Metab. 2020 06; 31(6):391-393.View Related Profiles. PMID: 32327275
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Neupane G, Acharya S, Bhattarai M, Upadhyay A, Belbase B, Bhandari M, Pandeya D, Pokharel S, Ghimire S, Thapa G, Karmacharya B, Bhatt MR, Spertus JA, Neupane D, Timsina L, Pokharel Y. Study, Design, and Rationale of Noncommunicable Diseases in Nepal (NCD Nepal) Study: A Community-Based Prospective Epidemiological and Implementation Study in Rural Nepal. Glob Adv Health Med. 2020; 9:2164956120917379. PMID: 32284911; PMCID: PMC7139172; DOI: 10.1177/2164956120917379;
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Toth PP, Dwyer JP, Cannon CP, Colhoun HM, Rader DJ, Upadhyay A, Louie MJ, Koren A, Letierce A, Mandel J, Banach M. Efficacy and safety of lipid lowering by alirocumab in chronic kidney disease. Kidney Int. 2018 06; 93(6):1397-1408. PMID: 29526502
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Stillman MD, Miller KH, Ziegler CH, Upadhyay A, Mitchell CK. Program Characteristics Influencing Allopathic Students' Residency Selection. J Am Osteopath Assoc. 2016 Apr; 116(4):214-26. PMID: 27018956; DOI: 10.7556/jaoa.2016.046;
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Upadhyay A, Inker LA, Levey AS. Chronic Kidney Disease: Definition, Classification and Approach to Management. Goldsmith D, Section editor. Oxford Textbook of Clinical Nephrology. Oxford University Press. Oxford, UK. 2015; 743-754.
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Wang K, Upadhyay A. Sugar-sweetened Beverages and Chronic Kidney Disease. US Endocrinology. 2015; 1(11):41-45; DOI: 10.17925/USE.2015. View Publication
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Upadhyay A. Statins in chronic kidney disease: what do meta-analyses tell us? Clin Exp Nephrol. 2014 Apr; 18(2):278-81. PMID: 24158229; DOI: 10.1007/s10157-013-0889-2;
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KDIGO Clinical Practice Guidelines for Lipid Management in Chronic Kidney Disease. Kidney Int Suppl. 2013; 3(3):s259-s305. View Publication
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Inker LA, Lafayette RA, Upadhyay A, Levey AS. Laboratory Evaluation of Kidney Disease. Schrier's Diseases of the Kidney. Editors: Coffman TM, Falk RJ, Molitoris BA, Neilson EG, Schrier RW. Lippincott Williams and Wilkins. Philadelphia, PA. 2012; 295-345.
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Upadhyay A, Earley A, Lamont JL, Haynes S, Wanner C, Balk EM. Lipid-lowering therapy in persons with chronic kidney disease: a systematic review and meta-analysis. Ann Intern Med. 2012 Aug 21; 157(4):251-62. PMID: 22910936; DOI: 10.7326/0003-4819-157-4-201208210-00005;
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KDIGO Clinical Practice Guidelines for Anemia in Chronic Kidney DIsease. Kidney Int Suppl. 2012; 2(4):s279-s335. View Publication
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Upadhyay A, Uhlig K. Is the lower blood pressure target for patients with chronic kidney disease supported by evidence? Curr Opin Cardiol. 2012 Jul; 27(4):370-3. PMID: 22525328; DOI: 10.1097/HCO.0b013e328353b934;
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KDIGO Clinical Practice Guideline for the Management of Blood Pressure in Chronic Kidney Disease. Kidney Int Suppl. 2012; 4(2):s337-414. View Publication
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Upadhyay A, Sarnak MJ, Levey AS. Bardoxolone methyl, chronic kidney disease, and type 2 diabetes. N Engl J Med. 2011 Nov 3; 365(18):1746; author reply 1746-7. PMID: 22047580; DOI: 10.1056/NEJMc1110239#SA3;
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Upadhyay A, Weiner DE. Lipid-lowering therapy in individuals with CKD: lessons learned from SHARP. Am J Kidney Dis. 2012 Feb; 59(2):170-3. PMID: 22033284; DOI: 10.1053/j.ajkd.2011.09.008;
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Upadhyay A, Uhlig K. Blood Pressure Targets in Chronic Kidney Disease: Response to Comment. Annals of Internal Medicine. 2011; 3(155):208.
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Upadhyay A, Earley A, Haynes SM, Uhlig K. Systematic review: blood pressure target in chronic kidney disease and proteinuria as an effect modifier. Ann Intern Med. 2011 Apr 19; 154(8):541-8. PMID: 21403055; DOI: 10.1059/0003-4819-154-8-201104190-00335;
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Yang Q, Köttgen A, Dehghan A, Smith AV, Glazer NL, Chen MH, Chasman DI, Aspelund T, Eiriksdottir G, Harris TB, Launer L, Nalls M, Hernandez D, Arking DE, Boerwinkle E, Grove ML, Li M, Linda Kao WH, Chonchol M, Haritunians T, Li G, Lumley T, Psaty BM, Shlipak M, Hwang SJ, Larson MG, O'Donnell CJ, Upadhyay A, van Duijn CM, Hofman A, Rivadeneira F, Stricker B, Uitterlinden AG, Paré G, Parker AN, Ridker PM, Siscovick DS, Gudnason V, Witteman JC, Fox CS, Coresh J. Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors. Circ Cardiovasc Genet. 2010 Dec; 3(6):523-30.View Related Profiles. PMID: 20884846; PMCID: PMC3371395; DOI: 10.1161/CIRCGENETICS.109.934455;
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Upadhyay A, Larson MG, Guo CY, Vasan RS, Lipinska I, O'Donnell CJ, Kathiresan S, Meigs JB, Keaney JF, Rong J, Benjamin EJ, Fox CS. Inflammation, kidney function and albuminuria in the Framingham Offspring cohort. Nephrol Dial Transplant. 2011 Mar; 26(3):920-6.View Related Profiles. PMID: 20682604; PMCID: PMC3108344; DOI: 10.1093/ndt/gfq471;
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Upadhyay A, Hwang SJ, Mitchell GF, Vasan RS, Vita JA, Stantchev PI, Meigs JB, Larson MG, Levy D, Benjamin EJ, Fox CS. Arterial stiffness in mild-to-moderate CKD. J Am Soc Nephrol. 2009 Sep; 20(9):2044-53.View Related Profiles. PMID: 19608701; PMCID: PMC2736768; DOI: 10.1681/ASN.2009010074;
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Köttgen A, Glazer NL, Dehghan A, Hwang SJ, Katz R, Li M, Yang Q, Gudnason V, Launer LJ, Harris TB, Smith AV, Arking DE, Astor BC, Boerwinkle E, Ehret GB, Ruczinski I, Scharpf RB, Chen YD, de Boer IH, Haritunians T, Lumley T, Sarnak M, Siscovick D, Benjamin EJ, Levy D, Upadhyay A, Aulchenko YS, Hofman A, Rivadeneira F, Uitterlinden AG, van Duijn CM, Chasman DI, Paré G, Ridker PM, Kao WH, Witteman JC, Coresh J, Shlipak MG, Fox CS. Multiple loci associated with indices of renal function and chronic kidney disease. Nat Genet. 2009 Jun; 41(6):712-7.View Related Profiles. PMID: 19430482; PMCID: PMC3039280; DOI: 10.1038/ng.377;
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Upadhyay A, Sosa MA, Jaber BL. Single-use versus reusable dialyzers: the known unknowns. Clin J Am Soc Nephrol. 2007 Sep; 2(5):1079-86.View Related Profiles. PMID: 17702728
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Jaber BL, Upadhyay A, Pereira BJG. Acute Complications of Hemodialysis. Comprehensive Clinical Nephrology. Editors: Feehally J, Floege J,Johnson RJ. Mosby Inc. Philadelphia. 2007.
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Upadhyay A, Jaber BL, Madias NE. Incidence and prevalence of hyponatremia. Am J Med. 2006 Jul; 119(7 Suppl 1):S30-5.View Related Profiles. PMID: 16843082
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Dawadi K, Pyakurel S, Sharma G, Sharma N, Upadhyay A. Human Biology and Health: A Review Book for the MBBS Entrance Exam. National Academy for Medical Education. Kathmandu. 1999.
This graph shows the total number of publications by year, by first, middle/unknown,
or last author.
Year | Publications |
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1999 | 1 |
2006 | 1 |
2007 | 2 |
2008 | 1 |
2009 | 3 |
2010 | 4 |
2011 | 5 |
2012 | 5 |
2013 | 4 |
2015 | 2 |
2016 | 2 |
2017 | 3 |
2018 | 1 |
2019 | 2 |
2020 | 3 |
2021 | 2 |
2022 | 1 |
2023 | 1 |
2024 | 2 |
2022 Boston University Chobanian & Avedisian School of Medicine:
Robert Dawson Evans Special Recognition Teaching Award
2021 Boston Medical Center:
Program Leadership Award
2012 Tufts University School of Medicine:
Citation for Notable Teaching
2011 Tufts University School of Medicine:
Citation for Accomplished Teaching
2007 St. Elizabeth's Medical Center:
Resident Teaching Award
2003 Tribhuvan University School of Medicine:
Gold Medals for the 1st position in medical school, basic medical sciences, pediatrics, and anatomy
Available to Mentor as: (Review Mentor Role Definitions):
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Advisor
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Co-Mentor or Peer Mentor
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Education Mentor
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Research / Scholarly Mentor
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Work / Life Integration Mentor