Joanne M. Murabito, MD
Associate Professor
Boston University School of Medicine
Dept of Medicine
General Internal Medicine

MD, Mount Sinai School of Medicine
ScM, Harvard University



Dr. Murabito is an Associate Professor of Medicine at Boston University School of Medicine and Co-PI at the Framingham Heart Study. Dr Murabito’s area of expertise is in epidemiology and genetic epidemiology. Her current research focuses on identifying the determinants of healthy aging and longevity and reproductive aging in the community including the investigation of genetic and genomic factors. She leads highly productive multidisciplinary international consortia including the Cohorts for Heart and Aging Research in Genomics Epidemiology (CHARGE) Aging and Longevity working group and the ReproGen Consortium. The Consortia bring together scientists interested in aging, longevity, and reproductive aging (menarche, menopause) and the relation of these traits to health outcomes and gene discovery.
Dr Murabito is also leading the introduction of mobile health into the Framingham Heart Study. She participated in an embedded physical activity trial using a smartphone app or activity tracker and would like to explore use of mHealth in older adults to improve health and function
Dr. Murabito continues to practice primary care at Boston Medical Center.

Research Center Director
Framingham Heart Study


Co-Principal Investigator
Framingham Heart Study



1999 Massachusetts Department of Public Health Breast Cancer Research Program Scientist


Mobile Health Technology for Cardiovascular Risk Reduction
10/15/2017 - 10/14/2020 (PI)
Robert Wood Johnson Foundation

The Jackson Laboratory Nathan Shock Center of Excellence in the Basic Biology of Aging
07/15/2015 - 06/30/2020 (PI)
Jackson Laboratory NIH NIA
2P30AG038070-07

Integrative resource to develop translational strategies to promote longevity
09/15/2015 - 04/30/2020 (PI)
Sutter Bay Hospitals dba California Pacific Medical Center NIH NIA
5U24AG051129-02

Identifying epigeneticmechanisms underlying age-related disease risk in CHARGE
09/30/2015 - 05/31/2018 (PI)
NIH/National Institute on Aging
3U34AG051418-02S1

The Long Life Family Study
06/01/2014 - 05/31/2018 (PI)
Boston Medical Center Corporation NIH NIA
5U01AG023755-11

Novel Multi-Omics Approach to the Biology of Health Aging: Framingham Study
09/15/2015 - 02/28/2018 (PI)
NIH/National Institute on Aging
2R56AG029451-05A1

Shock Center for Aging Research at the Jackson Laboratory
07/01/2010 - 06/30/2015 (PI)
Jackson Laboratory NIH NIA
5P30AG038070-05

Exceptional Aging Across the Life Span: Framingham Study
05/01/2008 - 04/30/2015 (PI)
NIH/National Institute on Aging
5R01AG029451-04

The Long Life Family Study
12/30/2013 - 04/30/2014 (PI)
Washington University NIH NIA
5U01AG023746-08

Genetics and Networks
04/15/2008 - 03/31/2013 (PI)
University of California, Los Angeles NIH NIA
5P01AG031093-04

Showing 10 of 12 results. Show All Results



Yr Title Project-Sub Proj Pubs
2016 Anti-Geronic Factors, GDF11 and Oxytocin, and Aging-Related Phenotypes 1R56AG052972-01
2016 IGF::OT::IGF FRAMINGHAM HEART STUDY (FHS) - TASK ORDER 02 268201500001I-0-26800003-1
2016 Identifying epigenetic mechanisms underlying age-related disease risk in CHARGE 5U34AG051418-02
2016 Identifying epigenetic mechanisms underlying age-related disease risk in CHARGE 3U34AG051418-02S1
2015 Identifying epigenetic mechanisms underlying age-related disease risk in CHARGE 1U34AG051418-01
2015 Novel multi-omics approach to the biology of healthy aging: Framingham Study 2R56AG029451-05A1
2011 Exceptional Aging Across the Life Span: Framingham Study 5R01AG029451-04 21
2010 Exceptional Aging Across the Life Span: Framingham Study 5R01AG029451-03 21
2009 Genetics of Reproductive Life Period and Health Outcomes 5R21AG032598-02 12
2009 Exceptional Aging Across the Life Span: Framingham Study 5R01AG029451-02 21
Showing 10 of 12 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Murabito JM, Zhao Q, Larson MG, Rong J, Lin H, Benjamin EJ, Levy D, Lunetta KL. Measures of Biologic Age in a Community Sample Predict Mortality and Age-Related Disease: The Framingham Offspring Study. J Gerontol A Biol Sci Med Sci. 2018 May 09; 73(6):757-762.View Related Profiles. PMID: 28977464.
     
  2. Mendelson MM, Johannes R, Liu C, Huan T, Yao C, Miao X, Murabito JM, Dupuis J, Levy D, Benjamin EJ, Lin H. Epigenome-Wide Association Study of Soluble Tumor Necrosis Factor Receptor 2 Levels in the Framingham Heart Study. Front Pharmacol. 2018; 9:207.View Related Profiles. PMID: 29740313; DOI: 10.3389/fphar.2018.00207;.
     
  3. Sarnowski C, Kavousi M, Isaacs S, Demerath EW, Broer L, Muka T, Franco OH, Ikram MA, Uitterlinden A, Franceschini N, Lunetta KL, Murabito JM. Genetic variants associated with earlier age at menopause increase the risk of cardiovascular events in women. Menopause. 2018 Apr; 25(4):451-457.View Related Profiles. PMID: 29112599.
     
  4. Haljas K, Amare AT, Alizadeh BZ, Hsu YH, Mosley T, Newman A, Murabito J, Tiemeier H, Tanaka T, van Duijn C, Ding J, Llewellyn DJ, Bennett DA, Terracciano A, Launer L, Ladwig KH, Cornelis MC, Teumer A, Grabe H, Kardia SLR, Ware EB, Smith JA, Snieder H, Eriksson JG, Groop L, Räikkönen K, Lahti J. Bivariate Genome-Wide Association Study of Depressive Symptoms With Type 2 Diabetes and Quantitative Glycemic Traits. Psychosom Med. 2018 Apr; 80(3):242-251. PMID: 29280852.
     
  5. Eriksson AL, Perry JRB, Coviello AD, Delgado GE, Ferrucci L, Hoffman AR, Huhtaniemi IT, Ikram MA, Karlsson MK, Kleber ME, Laughlin GA, Liu Y, Lorentzon M, Lunetta KL, Mellström D, Murabito JM, Murray A, Nethander M, Nielson CM, Prokopenko I, Pye SR, Raffel LJ, Rivadeneira F, Srikanth P, Stolk L, Teumer A, Travison TG, Uitterlinden AG, Vaidya D, Vanderschueren D, Zmuda JM, März W, Orwoll ES, Ouyang P, Vandenput L, Wu FCW, de Jong FH, Bhasin S, Kiel DP, Ohlsson C. Genetic Determinants of Circulating Estrogen Levels and Evidence of a Causal Effect of Estradiol on Bone Density in Men. J Clin Endocrinol Metab. 2018 03 01; 103(3):991-1004.View Related Profiles. PMID: 29325096.
     
  6. Beaumont RN, Warrington NM, Cavadino A, Tyrrell J, Nodzenski M, Horikoshi M, Geller F, Myhre R, Richmond RC, Paternoster L, Bradfield JP, Kreiner-Møller E, Huikari V, Metrustry S, Lunetta KL, Painter JN, Hottenga JJ, Allard C, Barton SJ, Espinosa A, Marsh JA, Potter C, Zhang G, Ang W, Berry DJ, Bouchard L, Das S, Hakonarson H, Heikkinen J, Helgeland Ø, Hocher B, Hofman A, Inskip HM, Jones SE, Kogevinas M, Lind PA, Marullo L, Medland SE, Murray A, Murray JC, Njølstad PR, Nohr EA, Reichetzeder C, Ring SM, Ruth KS, Santa-Marina L, Scholtens DM, Sebert S, Sengpiel V, Tuke MA, Vaudel M, Weedon MN, Willemsen G, Wood AR, Yaghootkar H, Muglia LJ, Bartels M, Relton CL, Pennell CE, Chatzi L, Estivill X, Holloway JW, Boomsma DI, Montgomery GW, Murabito JM, Spector TD, Power C, Järvelin MR, Bisgaard H, Grant SFA, Sørensen TIA, Jaddoe VW, Jacobsson B, Melbye M, McCarthy MI, Hattersley AT, Hayes MG, Frayling TM, Hivert MF, Felix JF, Hyppönen E, Lowe WL, Evans DM, Lawlor DA, Feenstra B, Freathy RM. Genome-wide association study of offspring birth weight in 86?577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics. Hum Mol Genet. 2018 Feb 15; 27(4):742-756.View Related Profiles. PMID: 29309628.
     
  7. Lu AT, Xue L, Salfati EL, Chen BH, Ferrucci L, Levy D, Joehanes R, Murabito JM, Kiel DP, Tsai PC, Yet I, Bell JT, Mangino M, Tanaka T, McRae AF, Marioni RE, Visscher PM, Wray NR, Deary IJ, Levine ME, Quach A, Assimes T, Tsao PS, Absher D, Stewart JD, Li Y, Reiner AP, Hou L, Baccarelli AA, Whitsel EA, Aviv A, Cardona A, Day FR, Wareham NJ, Perry JRB, Ong KK, Raj K, Lunetta KL, Horvath S. GWAS of epigenetic aging rates in blood reveals a critical role for TERT. Nat Commun. 2018 Jan 26; 9(1):387.View Related Profiles. PMID: 29374233.
     
  8. Lin H, Lunetta KL, Zhao Q, Rong J, Benjamin EJ, Mendelson MM, Joehanes R, Levy D, Larson MG, Murabito JM. Transcriptome-wide association study of inflammatory biologic age. Aging (Albany NY). 2017 Nov 11; 9(11):2288-2301.View Related Profiles. PMID: 29135455; DOI: 10.18632/aging.101321;.
     
  9. Patel MS, Benjamin EJ, Volpp KG, Fox CS, Small DS, Massaro JM, Lee JJ, Hilbert V, Valentino M, Taylor DH, Manders ES, Mutalik K, Zhu J, Wang W, Murabito JM. Effect of a Game-Based Intervention Designed to Enhance Social Incentives to Increase Physical Activity Among Families: The BE FIT Randomized Clinical Trial. JAMA Intern Med. 2017 Nov 01; 177(11):1586-1593.View Related Profiles. PMID: 28973115.
     
  10. Huan T, Chen G, Liu C, Bhattacharya A, Rong J, Chen BH, Seshadri S, Tanriverdi K, Freedman JE, Larson MG, Murabito JM, Levy D. Age-associated microRNA expression in human peripheral blood is associated with all-cause mortality and age-related traits. Aging Cell. 2018 Feb; 17(1).View Related Profiles. PMID: 29044988.
     
Showing 10 of 206 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 206 publications over 25 distinct years, with a maximum of 24 publications in 2013 and 2015

YearPublications
19901
19922
19931
19952
19971
19991
20002
20012
20023
20032
20044
200510
20063
200714
200811
20096
201010
201113
201219
201324
201410
201524
201616
201718
20187
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Aging
Cardiovascular disease
Epidemiology
Genetic Epidemiology
Menarche
Menopause

Available to Mentor as: (Review Mentor Role Definitions):
  • Research / Scholarly Mentor
Contact for Mentoring:


Framingham Heart Study 73 Mt Wayte Ave
Framingham MA 01702-5827
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