Joanne M. Murabito, MD
Professor
Boston University School of Medicine
Dept of Medicine
General Internal Medicine

MD, Mount Sinai School of Medicine




Dr. Murabito is a Professor of Medicine at Boston University School of Medicine and Co-PI at the Framingham Heart Study. Dr Murabito’s area of expertise is in epidemiology and genetic epidemiology. Her current research focuses on identifying the determinants of healthy aging and longevity and reproductive aging in the community including the investigation of genetic and genomic factors. She leads highly productive multidisciplinary international consortia including the Cohorts for Heart and Aging Research in Genomics Epidemiology (CHARGE) Aging and Longevity working group and the ReproGen Consortium. The Consortia bring together scientists interested in aging, longevity, and reproductive aging (menarche, menopause) and the relation of these traits to health outcomes and gene discovery.
Dr Murabito is also leading the introduction of mobile health into the Framingham Heart Study. She participated in an embedded physical activity trial using a smartphone app or activity tracker and would like to explore use of mHealth in older adults to improve health and function
Dr. Murabito continues to practice primary care at Boston Medical Center.

Primary Investigator; Research Center Director
Framingham Heart Study


Member
Boston University
Evans Center for Interdisciplinary Biomedical Research



1999 Massachusetts Department of Public Health Breast Cancer Research Program Scientist


FHS-NEXT - Framingham Novel EXam using Technology
11/01/2018 - 11/30/2022 (Multi-PI)
PI: Joanne M. Murabito, MD
NIH/National Heart, Lung, and Blood Institute
5R01HL141434-02

Mobile Health Technology for Cardiovascular Risk Reduction
10/15/2017 - 08/31/2021 (PI)
Robert Wood Johnson Foundation


The Jackson Laboratory Nathan Shock Center of Excellence in the Basic Biology of Aging
07/15/2015 - 06/30/2020 (Subcontract PI)
Jackson Laboratory NIH NIA
5P30AG038070-10

Integrative resource to develop translational strategies to promote longevity
09/15/2015 - 04/30/2020 (Subcontract PI)
Sutter Bay Hospitals dba California Pacific Medical Center NIH NIA
5U24AG051129-05

The Long Life Family Study
06/01/2014 - 07/31/2019 (Subcontract PI)
Boston Medical Center Corporation NIH NIA
5U01AG023755-13

Identifying epigeneticmechanisms underlying age-related disease risk in CHARGE
09/30/2015 - 05/31/2018 (PI)
NIH/National Institute on Aging
5U34AG051418-02

Novel Multi-Omics Approach to the Biology of Health Aging: Framingham Study
09/15/2015 - 02/28/2018 (Multi-PI)
PI: Joanne M. Murabito, MD
NIH/National Institute on Aging
2R56AG029451-05A1

Shock Center for Aging Research at the Jackson Laboratory
07/01/2010 - 06/30/2015 (Subcontract PI)
Jackson Laboratory NIH NIA
5P30AG038070-05

Exceptional Aging Across the Life Span: Framingham Study
05/01/2008 - 04/30/2015 (PI)
NIH/National Institute on Aging
5R01AG029451-04

The Long Life Family Study
12/30/2013 - 04/30/2014 (Subcontract PI)
The Washington University NIH NIA
5U01AG023746-08

Showing 10 of 13 results. Show All Results


Title


Yr Title Project-Sub Proj Pubs
2020 Role of Peripheral Immune Cells in Cognitive Aging: The Framingham Offspring Study 1R01AG067457-01
2020 FHS-NEXT - Framingham Novel EXam using Technology 5R01HL141434-02 5
2019 FHS-NEXT - Framingham Novel EXam using Technology 1R01HL141434-01A1 5
2016 IGF::OT::IGF FRAMINGHAM HEART STUDY (FHS) - TASK ORDER 02 268201500001I-0-26800003-1
2016 Identifying epigenetic mechanisms underlying age-related disease risk in CHARGE 5U34AG051418-02 1
2016 Identifying epigenetic mechanisms underlying age-related disease risk in CHARGE 3U34AG051418-02S1 1
2015 Identifying epigenetic mechanisms underlying age-related disease risk in CHARGE 1U34AG051418-01 1
2015 Novel multi-omics approach to the biology of healthy aging: Framingham Study 2R56AG029451-05A1 17
2011 Exceptional Aging Across the Life Span: Framingham Study 5R01AG029451-04 43
2010 Exceptional Aging Across the Life Span: Framingham Study 5R01AG029451-03 43
Showing 10 of 14 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Colicino E, Marioni R, Ward-Caviness C, Gondalia R, Guan W, Chen B, Tsai PC, Huan T, Xu G, Golareh A, Schwartz J, Vokonas P, Just A, Starr JM, McRae AF, Wray NR, Visscher PM, Bressler J, Zhang W, Tanaka T, Moore AZ, Pilling LC, Zhang G, Stewart JD, Li Y, Hou L, Castillo-Fernandez J, Spector T, Kiel DP, Murabito JM, Liu C, Mendelson M, Assimes T, Absher D, Tsaho PS, Lu AT, Ferrucci L, Wilson R, Waldenberger M, Prokisch H, Bandinelli S, Bell JT, Levy D, Deary IJ, Horvath S, Pankow J, Peters A, Whitsel EA, Baccarelli A. Blood DNA methylation sites predict death risk in a longitudinal study of 12, 300 individuals. Aging (Albany NY). 2020 Jul 22; 12.View Related Profiles. PMID: 32697766
     
  2. Feitosa MF, Lunetta KL, Wang L, Wojczynski MK, Kammerer CM, Perls T, Schupf N, Christensen K, Murabito JM, Province MA. Gene discovery for high-density lipoprotein cholesterol level change over time in prospective family studies. Atherosclerosis. 2020 03; 297:102-110.View Related Profiles. PMID: 32109663
     
  3. Newman AB, Kritchevsky SB, Guralnik JM, Cummings SR, Salive M, Kuchel GA, Schrack J, Morris MC, Weir D, Baccarelli A, Murabito JM, Ben-Shlomo Y, Espeland MA, Kirkland J, Melzer D, Ferrucci L. Accelerating the Search for Interventions Aimed at Expanding the Health Span in Humans: The Role of Epidemiology. J Gerontol A Biol Sci Med Sci. 2020 01 01; 75(1):77-86. PMID: 31722007
     
  4. Spartano NL, Demissie S, Himali JJ, Dukes KA, Murabito JM, Vasan RS, Beiser AS, Seshadri S. Accelerometer-determined physical activity and cognitive function in middle-aged and older adults from two generations of the Framingham Heart Study. Alzheimers Dement (N Y). 2019; 5:618-626.View Related Profiles. PMID: 31660424
     
  5. Bae H, Lunetta KL, Murabito JM, Andersen SL, Schupf N, Perls T, Sebastiani P. Genetic associations with age of menopause in familial longevity. Menopause. 2019 10; 26(10):1204-1212.View Related Profiles. PMID: 31188284
     
  6. Spartano NL, Lin H, Sun F, Lunetta KL, Trinquart L, Valentino M, Manders ES, Pletcher MJ, Marcus GM, McManus DD, Benjamin EJ, Fox CS, Olgin JE, Murabito JM. Comparison of On-Site Versus Remote Mobile Device Support in the Framingham Heart Study Using the Health eHeart Study for Digital Follow-up: Randomized Pilot Study Set Within an Observational Study Design. JMIR Mhealth Uhealth. 2019 09 30; 7(9):e13238.View Related Profiles. PMID: 31573928; DOI: 10.2196/13238;
     
  7. Johnson ND, Huang L, Li R, Li Y, Yang Y, Kim HR, Grant C, Wu H, Whitsel EA, Kiel DP, Baccarelli AA, Jin P, Murabito JM, Conneely KN. Age-related DNA hydroxymethylation is enriched for gene expression and immune system processes in human peripheral blood. Epigenetics. 2020 Mar; 15(3):294-306. PMID: 31506003
     
  8. Lin H, Rogers GT, Lunetta KL, Levy D, Miao X, Troy LM, Jacques PF, Murabito JM. Healthy diet is associated with gene expression in blood: the Framingham Heart Study. Am J Clin Nutr. 2019 09 01; 110(3):742-749.View Related Profiles. PMID: 31187853; DOI: 10.1093/ajcn/nqz060;
     
  9. Deelen J, Evans DS, Arking DE, Tesi N, Nygaard M, Liu X, Wojczynski MK, Biggs ML, van der Spek A, Atzmon G, Ware EB, Sarnowski C, Smith AV, Seppälä I, Cordell HJ, Dose J, Amin N, Arnold AM, Ayers KL, Barzilai N, Becker EJ, Beekman M, Blanché H, Christensen K, Christiansen L, Collerton JC, Cubaynes S, Cummings SR, Davies K, Debrabant B, Deleuze JF, Duncan R, Faul JD, Franceschi C, Galan P, Gudnason V, Harris TB, Huisman M, Hurme MA, Jagger C, Jansen I, Jylhä M, Kähönen M, Karasik D, Kardia SLR, Kingston A, Kirkwood TBL, Launer LJ, Lehtimäki T, Lieb W, Lyytikäinen LP, Martin-Ruiz C, Min J, Nebel A, Newman AB, Nie C, Nohr EA, Orwoll ES, Perls TT, Province MA, Psaty BM, Raitakari OT, Reinders MJT, Robine JM, Rotter JI, Sebastiani P, Smith J, Sørensen TIA, Taylor KD, Uitterlinden AG, van der Flier W, van der Lee SJ, van Duijn CM, van Heemst D, Vaupel JW, Weir D, Ye K, Zeng Y, Zheng W, Holstege H, Kiel DP, Lunetta KL, Slagboom PE, Murabito JM. A meta-analysis of genome-wide association studies identifies multiple longevity genes. Nat Commun. 2019 08 14; 10(1):3669.View Related Profiles. PMID: 31413261
     
  10. Huan T, Mendelson M, Joehanes R, Yao C, Liu C, Song C, Bhattacharya A, Rong J, Tanriverdi K, Keefe J, Murabito JM, Courchesne P, Larson MG, Freedman JE, Levy D. Epigenome-wide association study of DNA methylation and microRNA expression highlights novel pathways for human complex traits. Epigenetics. 2020 Jan - Feb; 15(1-2):183-198.View Related Profiles. PMID: 31282290
     
Showing 10 of 224 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 224 publications over 27 distinct years, with a maximum of 24 publications in 2013 and 2015

YearPublications
19901
19922
19931
19952
19971
19991
20002
20012
20023
20032
20044
200510
20063
200714
200811
20096
201010
201113
201219
201324
201410
201524
201616
201718
20187
201915
20203
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Aging
Cardiovascular disease
Epidemiology
Genetic Epidemiology
Menarche
Menopause

Available to Mentor as: (Review Mentor Role Definitions):
  • Research / Scholarly Mentor
Contact for Mentoring:

Framingham Heart Study 73 Mt Wayte Ave
Framingham MA 01702-5827
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