Joanne M. Murabito, MD
Boston University School of Medicine
Dept of Medicine
General Internal Medicine

MD, Mount Sinai School of Medicine
ScM, Harvard University

Dr. Murabito is a Professor of Medicine at Boston University School of Medicine and Co-PI at the Framingham Heart Study. Dr Murabito’s area of expertise is in epidemiology and genetic epidemiology. Her current research focuses on identifying the determinants of healthy aging and longevity and reproductive aging in the community including the investigation of genetic and genomic factors. She leads highly productive multidisciplinary international consortia including the Cohorts for Heart and Aging Research in Genomics Epidemiology (CHARGE) Aging and Longevity working group and the ReproGen Consortium. The Consortia bring together scientists interested in aging, longevity, and reproductive aging (menarche, menopause) and the relation of these traits to health outcomes and gene discovery.
Dr Murabito is also leading the introduction of mobile health into the Framingham Heart Study. She participated in an embedded physical activity trial using a smartphone app or activity tracker and would like to explore use of mHealth in older adults to improve health and function
Dr. Murabito continues to practice primary care at Boston Medical Center.

Research Center Director
Framingham Heart Study

Co-Principal Investigator
Framingham Heart Study

1999 Massachusetts Department of Public Health Breast Cancer Research Program Scientist

FHS-NEXT - Framingham Novel EXam using Technology
11/01/2018 - 11/30/2022 (PI)
NIH/National Heart, Lung, and Blood Institute

Mobile Health Technology for Cardiovascular Risk Reduction
10/15/2017 - 10/14/2020 (PI)
Robert Wood Johnson Foundation

The Jackson Laboratory Nathan Shock Center of Excellence in the Basic Biology of Aging
07/15/2015 - 06/30/2020 (PI)
Jackson Laboratory NIH NIA

Integrative resource to develop translational strategies to promote longevity
09/15/2015 - 04/30/2020 (PI)
Sutter Bay Hospitals dba California Pacific Medical Center NIH NIA

The Long Life Family Study
06/01/2014 - 05/31/2019 (PI)
Boston Medical Center Corporation NIH NIA

Identifying epigeneticmechanisms underlying age-related disease risk in CHARGE
09/30/2015 - 05/31/2018 (PI)
NIH/National Institute on Aging

Novel Multi-Omics Approach to the Biology of Health Aging: Framingham Study
09/15/2015 - 02/28/2018 (PI)
NIH/National Institute on Aging

Shock Center for Aging Research at the Jackson Laboratory
07/01/2010 - 06/30/2015 (PI)
Jackson Laboratory NIH NIA

Exceptional Aging Across the Life Span: Framingham Study
05/01/2008 - 04/30/2015 (PI)
NIH/National Institute on Aging

The Long Life Family Study
12/30/2013 - 04/30/2014 (PI)
The Washington University NIH NIA

Showing 10 of 13 results. Show All Results

Yr Title Project-Sub Proj Pubs
2019 FHS-NEXT - Framingham Novel EXam using Technology 1R01HL141434-01A1
2016 IGF::OT::IGF FRAMINGHAM HEART STUDY (FHS) - TASK ORDER 02 268201500001I-0-26800003-1
2016 Identifying epigenetic mechanisms underlying age-related disease risk in CHARGE 5U34AG051418-02 1
2016 Identifying epigenetic mechanisms underlying age-related disease risk in CHARGE 3U34AG051418-02S1 1
2015 Identifying epigenetic mechanisms underlying age-related disease risk in CHARGE 1U34AG051418-01 1
2015 Novel multi-omics approach to the biology of healthy aging: Framingham Study 2R56AG029451-05A1 5
2011 Exceptional Aging Across the Life Span: Framingham Study 5R01AG029451-04 24
2010 Exceptional Aging Across the Life Span: Framingham Study 5R01AG029451-03 24
2009 Genetics of Reproductive Life Period and Health Outcomes 5R21AG032598-02 12
2009 Exceptional Aging Across the Life Span: Framingham Study 5R01AG029451-02 24
Showing 10 of 12 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. McManus DD, Trinquart L, Benjamin EJ, Manders ES, Fusco K, Jung LS, Spartano NL, Kheterpal V, Nowak C, Sardana M, Murabito JM. Design and Preliminary Findings From a New Electronic Cohort Embedded in the Framingham Heart Study. J Med Internet Res. 2019 Mar 01; 21(3):e12143.View Related Profiles. PMID: 30821691.
  2. Orkaby AR, Lunetta KL, Sun FJ, Driver JA, Benjamin EJ, Hamburg NM, Mitchell GF, Vasan RS, Murabito JM. Cross-Sectional Association of Frailty and Arterial Stiffness in Community-Dwelling Older Adults: The Framingham Heart Study. J Gerontol A Biol Sci Med Sci. 2019 Feb 15; 74(3):373-379.View Related Profiles. PMID: 29917058.
  3. Spartano NL, Lyass A, Larson MG, Tran T, Andersson C, Blease SJ, Esliger DW, Vasan RS, Murabito JM. Objective physical activity and physical performance in middle-aged and older adults. Exp Gerontol. 2019 May; 119:203-211.View Related Profiles. PMID: 30771463.
  4. Spartano NL, Davis-Plourde KL, Himali JJ, Murabito JM, Vasan RS, Beiser AS, Seshadri S. Self-Reported Physical Activity and Relations to Growth and Neurotrophic Factors in Diabetes Mellitus: The Framingham Offspring Study. J Diabetes Res. 2019; 2019:2718465.View Related Profiles. PMID: 30729134; DOI: 10.1155/2019/2718465;.
  5. Lin H, Lunetta KL, Zhao Q, Mandaviya PR, Rong J, Benjamin EJ, Joehanes R, Levy D, van Meurs JBJ, Larson MG, Murabito JM. Whole Blood Gene Expression Associated With Clinical Biological Age. J Gerontol A Biol Sci Med Sci. 2019 Jan 01; 74(1):81-88.View Related Profiles. PMID: 30010802.
  6. Murabito JM, Zhao Q, Larson MG, Rong J, Lin H, Benjamin EJ, Levy D, Lunetta KL. Measures of Biologic Age in a Community Sample Predict Mortality and Age-Related Disease: The Framingham Offspring Study. J Gerontol A Biol Sci Med Sci. 2018 May 09; 73(6):757-762.View Related Profiles. PMID: 28977464.
  7. Mendelson MM, Johannes R, Liu C, Huan T, Yao C, Miao X, Murabito JM, Dupuis J, Levy D, Benjamin EJ, Lin H. Epigenome-Wide Association Study of Soluble Tumor Necrosis Factor Receptor 2 Levels in the Framingham Heart Study. Front Pharmacol. 2018; 9:207.View Related Profiles. PMID: 29740313; DOI: 10.3389/fphar.2018.00207;.
  8. Sarnowski C, Kavousi M, Isaacs S, Demerath EW, Broer L, Muka T, Franco OH, Ikram MA, Uitterlinden A, Franceschini N, Lunetta KL, Murabito JM. Genetic variants associated with earlier age at menopause increase the risk of cardiovascular events in women. Menopause. 2018 04; 25(4):451-457.View Related Profiles. PMID: 29112599.
  9. Haljas K, Amare AT, Alizadeh BZ, Hsu YH, Mosley T, Newman A, Murabito J, Tiemeier H, Tanaka T, van Duijn C, Ding J, Llewellyn DJ, Bennett DA, Terracciano A, Launer L, Ladwig KH, Cornelis MC, Teumer A, Grabe H, Kardia SLR, Ware EB, Smith JA, Snieder H, Eriksson JG, Groop L, Räikkönen K, Lahti J. Bivariate Genome-Wide Association Study of Depressive Symptoms With Type 2 Diabetes and Quantitative Glycemic Traits. Psychosom Med. 2018 04; 80(3):242-251. PMID: 29280852.
  10. Eriksson AL, Perry JRB, Coviello AD, Delgado GE, Ferrucci L, Hoffman AR, Huhtaniemi IT, Ikram MA, Karlsson MK, Kleber ME, Laughlin GA, Liu Y, Lorentzon M, Lunetta KL, Mellström D, Murabito JM, Murray A, Nethander M, Nielson CM, Prokopenko I, Pye SR, Raffel LJ, Rivadeneira F, Srikanth P, Stolk L, Teumer A, Travison TG, Uitterlinden AG, Vaidya D, Vanderschueren D, Zmuda JM, März W, Orwoll ES, Ouyang P, Vandenput L, Wu FCW, de Jong FH, Bhasin S, Kiel DP, Ohlsson C. Genetic Determinants of Circulating Estrogen Levels and Evidence of a Causal Effect of Estradiol on Bone Density in Men. J Clin Endocrinol Metab. 2018 03 01; 103(3):991-1004.View Related Profiles. PMID: 29325096.
Showing 10 of 211 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 211 publications over 26 distinct years, with a maximum of 24 publications in 2013 and 2015

In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Cardiovascular disease
Genetic Epidemiology

Available to Mentor as: (Review Mentor Role Definitions):
  • Research / Scholarly Mentor
Contact for Mentoring:

Framingham Heart Study 73 Mt Wayte Ave
Framingham MA 01702-5827
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