Nicole Spartano, PhD
Research Assistant Professor
Boston University School of Medicine
Dept of Medicine
Endocrinology, Diabetes, Nutrition & Weight Management

PhD, Tufts University
MS, Tufts University

Nicole Spartano, PhD is a Research Assistant Professor of Medicine in Endocrinology, Diabetes, Nutrition and Weight Management at the Boston University School of Medicine. She also serves as the Co-Director of the Physical Activity Station at the Framingham Heart Study, overseeing data collection using accelerometers (fitness trackers). She has received funding from the American Heart Association and Alzheimer's Association to understand the impact of physical activity throughout the lifecourse on brain health and the risk for dementia and Alzheimer's disease.

She also has a major research interest in using mobile health technology to improve health in underserved patient populations at Boston Medical Center. She is exploring the use of continuous glucose monitors as a tool for enhancing lifestyle interventions in patients with and without diabetes mellitus. She shares a MPI role on a Focused Research Project funded by Boston University’s Hariri Institute, which facilitates collaborations of clinical and computational investigators. This team is developing a software platform that can continuously collect mobile health data from research participants and patients. The goal of creating this platform is to address challenges in privacy and in providing timely communication to medically vulnerable patients.

Dr. Spartano also teaches courses for Boston University Graduate Medical Sciences, School of Public Health, and Sargent College of Health Sciences.

Framingham Heart Study

Boston University
Evans Center for Interdisciplinary Biomedical Research

Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Graduate Medical Sciences

2018 American Heart Association: Sandra A. Daugherty Award, Finalist
2017 American Heart Association Specialty Conferences : Best of American Heart Association Specialty Conferences
2016 American Heart Association: Early Investigator Travel Award
2015 American Heart Association Specialty Conferences: Best of American Heart Association Specialty Conferences
2015 Boston University Professional Development & Postdoctoral Affairs: Travel Award
2014-2016 NIH/NHLBI: Postdoctoral Training Grant award
2009-2012 NIH/NHLBI: Pre-doctoral Training Grant award
2007-2009 Tufts University: Friedman School of Nutrition Scholarship
2006 Syracuse University: Biology Award for Research Excellence

The Longitudinal Influence of Midlife Physical Activity and Sedentary Time on Vascular Brain Injury
07/01/2016 - 06/30/2019 (PI)
American Heart Association

Physical Inactivity, Epigenetic Aging, and Preclinical Dementia
12/01/2018 - 11/30/2021 (PI)
Alzheimer's Association


Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Zhang Y, Pathiravasan CH, Hammond MM, Liu H, Lin H, Sardana M, Trinquart L, Borrelli B, Manders ES, Kornej J, Spartano NL, Nowak C, Kheterpal V, Benjamin EJ, McManus DD, Murabito JM, Liu C. Comparison of Daily Routines Between Middle-aged and Older Participants With and Those Without Diabetes in the Electronic Framingham Heart Study: Cohort Study. JMIR Diabetes. 2022 Jan 07; 7(1):e29107.View Related Profiles. PMID: 34994694; DOI: 10.2196/29107;
  2. Tarp J, Fagerland MW, Dalene KE, Johannessen JS, Hansen BH, Jefferis BJ, Whincup PH, Diaz KM, Hooker S, Howard VJ, Chernofsky A, Larson MG, Spartano NL, Vasan RS, Dohrn IM, Hagströmer M, Edwardson C, Yates T, Shiroma EJ, Dempsey PC, Wijndaele K, Anderssen SA, Lee IM, Ekelund U. Device-measured physical activity, adiposity and mortality: a harmonised meta-analysis of eight prospective cohort studies. Br J Sports Med. 2021 Dec 07.View Related Profiles. PMID: 34876405
  3. Spartano NL, Himali JJ, Trinquart L, Yang Q, Weinstein G, Satizabal CL, Dukes KA, Beiser AS, Murabito JM, Vasan RS, Seshadri S. Accelerometer-Measured, Habitual Physical Activity and Circulating Brain-Derived Neurotrophic Factor: A Cross-Sectional Study. J Alzheimers Dis. 2021 Nov 29.View Related Profiles. PMID: 34864673; DOI: 10.3233/JAD-215109;
  4. Nayor M, Chernofsky A, Spartano NL, Tanguay M, Blodgett JB, Murthy VL, Malhotra R, Houstis NE, Velagaleti RS, Murabito JM, Larson MG, Vasan RS, Shah RV, Lewis GD. Physical activity and fitness in the community: the Framingham Heart Study. Eur Heart J. 2021 11 21; 42(44):4565-4575.View Related Profiles. PMID: 34436560; PMCID: PMC8633734; DOI: 10.1093/eurheartj/ehab580;
  5. Spartano NL. What Are the Next Steps for Developing a National Steps Guideline? JAMA Netw Open. 2021 09 01; 4(9):e2125267. PMID: 34477855
  6. Sardana M, Lin H, Zhang Y, Liu C, Trinquart L, Benjamin EJ, Manders ES, Fusco K, Kornej J, Hammond MM, Spartano N, Pathiravasan CH, Kheterpal V, Nowak C, Borrelli B, Murabito JM, McManus DD. Association of Habitual Physical Activity With Home Blood Pressure in the Electronic Framingham Heart Study (eFHS): Cross-sectional Study. J Med Internet Res. 2021 06 24; 23(6):e25591.View Related Profiles. PMID: 34185019; PMCID: PMC8277303; DOI: 10.2196/25591;
  7. Barone Gibbs B, Hivert MF, Jerome GJ, Kraus WE, Rosenkranz SK, Schorr EN, Spartano NL, Lobelo F. Physical Activity as a Critical Component of First-Line Treatment for Elevated Blood Pressure or Cholesterol: Who, What, and How?: A Scientific Statement From the American Heart Association. Hypertension. 2021 08; 78(2):e26-e37. PMID: 34074137
  8. Lee J, Walker ME, Bourdillon MT, Spartano NL, Rogers GT, Jacques PF, Vasan RS, Xanthakis V. Conjoint Associations of Adherence to Physical Activity and Dietary Guidelines With Cardiometabolic Health: The Framingham Heart Study. J Am Heart Assoc. 2021 04 06; 10(7):e019800.View Related Profiles. PMID: 33784828; PMCID: PMC8174320; DOI: 10.1161/JAHA.120.019800;
  9. Pathiravasan CH, Zhang Y, Trinquart L, Benjamin EJ, Borrelli B, McManus DD, Kheterpal V, Lin H, Sardana M, Hammond MM, Spartano NL, Dunn AL, Schramm E, Nowak C, Manders ES, Liu H, Kornej J, Liu C, Murabito JM. Adherence of Mobile App-Based Surveys and Comparison With Traditional Surveys: eCohort Study. J Med Internet Res. 2021 01 20; 23(1):e24773.View Related Profiles. PMID: 33470944; PMCID: PMC7857942; DOI: 10.2196/24773;
  10. Spartano NL, Pantoni L. What Can Longitudinal Observational Studies of Physical Activity Teach Us About Prevention of Dementia? Neurology. 2021 02 16; 96(7):297-298. PMID: 33408143
Showing 10 of 43 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 43 publications over 10 distinct years, with a maximum of 9 publications in 2021


Recent (within 3 months)

How to improve your fitness if you sit down all day, according to experts

Stylist 11/1/2021


How many steps should you take a day? Hitting 7,000 may reduce risk of early death, study says

USA Today 9/16/2021

Taking 7,000 Steps Or More A Day May Lower Mortality Risk

South Florida Reporter 9/12/2021

How many steps a day should you take? Study finds 7,000 can go a long way

NBC News 9/12/2021

Secret Side Effects of Exercising Just 2 Hours Per Week, Says Science

Eat This, Not That 8/3/2021

Exercise at Midlife Linked to Better Brain Health in Late Life

Medscape 1/15/2021

Midlife Physical Activity Correlates With Late-Life Brain Structure

MedPage Today 1/6/2021

AHA News: 5 Easy Ways to Keep Tabs on Heart Health

U.S. News & World Report 7/29/2020

Even a Little Exercise May Bring a Brain Boost

U.S. News & World Report 11/6/2019

Even a Little Exercise May Bring a Brain Boost

Health Day 11/6/2019

Rethinking the approach to fighting Alzheimer’s disease

The Conversation 8/13/2019

Light physical activity might help keep the brain young

Reuters 5/15/2019

Light Physical Activity Associated With Increased Brain Volume

Healio 5/3/2019

Light Is Alright: Mild Physical Activity Comes With Larger Brain

Alzheimer’s Forum 4/26/2019

Light Intensity Physical Activity Promotes Healthy Brain Aging

Coastal Ledger 4/23/2019

Doing This For Just a Few Minutes Each Day Can Improve Your Brain and Body

Thrive Global 4/23/2019

Family Chores Can Maintain Your Mind Younger: Research

Infosurhoy 4/23/2019

Every Single Minute Of Physical Activity Helps Health, Study Shows

Mother Nature Network 4/22/2019

Even a Little More Exercise Might Help Your Brain Stay Young

HealthDay News 4/19/2019

Housework Could Keep Brain Young, Research Suggests

The Guardian 4/19/2019

Even a Little Bit of Exercise Can Keep Your Brain From Shrinking, Study Suggests

Gizmodo 4/19/2019

Light Activity And Even Housework Can Keep Our Brains Young, A New Study Suggests

The National 4/19/2019

Reducing Brain Aging May Be As Simple As Light Physical Activity

Slash Gear 4/19/2019

Want to Maintain Total Cerebral Brain Volume? Keep Walking

Psychology Today 4/19/2019

15 daily habits that might be ageing you prematurely

Reader's Digest Australia 4/16/2019

15 Daily Habits That Might Be Aging You Prematurely

Reader's Digest 11/6/2018

Even light exercise might lessen severity of a future stroke

Reuters 10/4/2018

Light to Moderate Physical Activity Can Lower Stroke Severity

Neurology Live 9/25/2018

Stroke severity reduced in those who walk regularly

Medical News Today 9/20/2018

First-Time Stroke Severity Tied Partly to Physical Activity

MedPage Today 9/19/2018

Weight loss wearables most effective alongside additional efforts, researchers explain

Mobi Health News 8/15/2018

44-Year Study Ties Midlife Fitness to Lower Dementia Risk

Alzforum 3/28/2018
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