Nicole Spartano, PhD is an Assistant Professor of Medicine in Endocrinology, Diabetes, Nutrition and Weight Management at the Chobanian and Avedisian School of Medicine. She serves as the Director of the Glucose Monitoring Station at the Framingham Heart Study. This study is funded through an R01 from the National Institute of Diabetes and Digestive and Kidney Diseases (Spartano, PI) to use continuous glucose monitors in a non-diabetic population to measure glucose patterns that may predict the development of diabetes. She also serves as the Co-Director of the Physical Activity Station at the Framingham Heart Study, overseeing data collection using accelerometers (fitness trackers). She has received funding from the American Heart Association and Alzheimer's Association to understand the impact of physical activity throughout the lifecourse on brain health and the risk for dementia and Alzheimer's disease.
Dr. Spartano also has a major research interest in using mobile health technology to improve health in underserved patient populations at Boston Medical Center. She is exploring the use of continuous glucose monitors as a tool for enhancing lifestyle interventions in patients with and without diabetes mellitus. She shares a MPI role on a Focused Research Project funded by Boston University’s Hariri Institute, which facilitates collaborations of clinical and computational investigators. This team is developing a software platform that can continuously collect mobile health data from research participants and patients. The goal of creating this platform is to address challenges in privacy and in providing timely communication to medically vulnerable patients.
Dr. Spartano also teaches courses for Boston University Graduate Medical Sciences, School of Public Health, and Sargent College of Health Sciences.
Diversity, Equity, Inclusion and Accessibility
My experiences as a foster parent have provided a lens through which I recognize the impact of structural inequality and the potential power of public policies and programs that would help to stabilize and uplift marginalized people. What has been very clear through my experiences fostering children, is that biological families love their kids and most often want to keep their families intact. However, these parents are struggling and are not properly supported by a system that should be assisting them, but often offers inadequate care, especially for mental health and substance use disorders. Through this experience, I have learned that it is only by supporting underserved adults through policies and structures that we will truly support vulnerable children.
In my research using mobile health technology, I am working with the BU CTSI Community Engagement Program to develop strategies to use continuous glucose monitors as a tool for enhancing weight- and diabetes-management interventions in underserved patients. I serve as one of the PIs of a Focused Research Project, funded by the Hariri Institute, Application of machine learning approaches to continuously collected mobile health data among medically vulnerable patients and large cohort populations. One of the goals of this project is to identify challenges and strategies to implementing mobile health research in underrepresented and underserved populations. The promises of technology to improve healthcare are not now distributed equally among marginalized populations. Therefore, this work is important so that advances in health technology reach marginalized populations and do not, instead, worsen health disparities.
My eventual goal is to meld my personal interest in supporting families struggling with mental health disorders with my research using mobile health technology. I am slowly making progress toward that end and I am very interested in collaborating on this topic. In the classroom, I am committed to learning how best to teach lessons on health disparities by framing this topic with discussions about the influence of structural inequities and to support and mentor students who may have faced these inequities.
How to become a foster parent:
If you have ever thought about fostering, please feel free to reach out to me! The Department of Child and Family Services provides a training course to prepare you before you take a placement. You can start with minimal commitment to provide “respite” (short-term placements for a weekend or a few nights for a foster family that may have other commitments during that time). You can specify child ages that you are open to and you can always say “no” if you are not comfortable with a situation. If you live in MA, the website is here to learn more: https://www.mass.gov/how-to/apply-to-become-a-dcf-foster-parent
My partner and I chose this lifestyle because we felt it the best way we can serve our community, and as a way to teach our sons the value of supporting families at their most pivotal time of need. There are many flaws to the foster care system, but the most immediate problem is the extreme shortage of foster homes. Many children end up sleeping at the DCF offices, in the backseat of social worker’s cars, or worse, they are placed in group homes or medical facilities because there are not enough foster families. I hope that someone who stumbles onto this page may see foster care as an option for them.
Investigator
Framingham Heart Study
Member
Boston University
Evans Center for Interdisciplinary Biomedical Research
Graduate Faculty (Primary Mentor of Grad Students)
Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences
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- Data is sorted by project end date, and updated monthly.
This tab shows grant data from BU Sponsored Research. It includes:
- Grant title
- Project period and this person’s role on the grant
- PI name, if this person is not the PI (the name will link if PI has a BU Profile)
- Funding source(s). An arrow indicates the flow of funding if multiple sponsors.
- Some grants will show an agency award/project number, and may be a link.
- Data is sorted by project end date, and updated monthly.
This tab shows grant data that did not automatically get imported into Profiles
from BU or BMC sources.
- Grant title
- Project period and this person’s role on the grant
- PI name, if this person is not the PI (the name will link if PI has a BU Profile)
- Funding source(s). An arrow indicates the flow of funding if multiple sponsors.
- Some grants will show an agency award/project number, and may be a link.
- Data is sorted by project end date, and updated monthly.
This tab shows grant data from the Boston VA. We are only showing grant title, and only for people in the role of PI.
Continuous glucose monitoring: determinants and prediction of diabetes mellitus development in the Framingham Heart Study04/01/2022 - 03/31/2027 (PI)
NIH/National Diabetes & Digestive & Kidney Diseases5R01DK129305-03
The Longitudinal Influence of Midlife Physical Activity and Sedentary Time on Vascular Brain Injury07/01/2016 - 06/30/2019 (PI)
American Heart Association
Massachusetts AI and Technology Center for Connected Care in Aging and Alzheimer's Disease09/01/2023 - 05/31/2025 (Subcontract PI)
PI:
Nicole Spartano, PhDUniversity of Massachusetts / UMASS NIH NIA
Physical Inactivity, Epigenetic Aging, and Preclinical Dementia12/01/2020 - 05/31/2022 (PI)
Alzheimer’s Association
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Publications listed below are automatically derived from MEDLINE/PubMed and other
sources, which might result in incorrect or missing publications. Faculty can
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Klonoff DC, Freckmann G, Pleus S, Kovatchev BP, Kerr D, Tse CC, Li C, Agus MSD, Dungan K, Voglová Hagerf B, Krouwer JS, Lee WA, Misra S, Rhee SY, Sabharwal A, Seley JJ, Shah VN, Tran NK, Waki K, Worth C, Tian T, Aaron RE, Rutledge K, Ho CN, Ayers AT, Adler A, Ahn DT, Aktürk HK, Al-Sofiani ME, Bailey TS, Baker M, Bally L, Bannuru RR, Bauer EM, Bee YM, Blanchette JE, Cengiz E, Chase JG, Y Chen K, Cherñavvsky D, Clements M, Cote GL, Dhatariya KK, Drincic A, Ejskjaer N, Espinoza J, Fabris C, Fleming GA, Gabbay MAL, Galindo RJ, Gómez-Medina AM, Heinemann L, Hermanns N, Hoang T, Hussain S, Jacobs PG, Jendle J, Joshi SR, Koliwad SK, Lal RA, Leiter LA, Lind M, Mader JK, Maran A, Masharani U, Mathioudakis N, McShane M, Mehta C, Moon SJ, Nichols JH, O'Neal DN, Pasquel FJ, Peters AL, Pfützner A, Pop-Busui R, Ranjitkar P, Rhee CM, Sacks DB, Schmidt S, Schwaighofer SM, Sheng B, Simonson GD, Sode K, Spanakis EK, Spartano NL, Umpierrez GE, Vareth M, Vesper HW, Wang J, Wright E, Wu AHB, Yeshiwas S, Zilbermint M, Kohn MA. The Diabetes Technology Society Error Grid and Trend Accuracy Matrix for Glucose Monitors. J Diabetes Sci Technol. 2024 Nov; 18(6):1346-1361. PMID: 39369312; PMCID: PMC11531029; DOI: 10.1177/19322968241275701;
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Spartano NL, Sultana N, Lin H, Cheng H, Lu S, Fei D, Murabito JM, Walker ME, Wolpert HA, Steenkamp DW. Defining continuous glucose monitor time in range in a large community-based cohort without diabetes. J Clin Endocrinol Metab. 2024 Sep 11.View Related Profiles. PMID: 39257191; DOI: 10.1210/clinem/dgae626;
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Spartano NL, Zhang Y, Liu C, Chernofsky A, Lin H, Trinquart L, Borrelli B, Pathiravasan CH, Kheterpal V, Nowak C, Vasan RS, Benjamin EJ, McManus DD, Murabito JM. Agreement Between Apple Watch and Actical Step Counts in a Community Setting: Cross-Sectional Investigation From the Framingham Heart Study. JMIR Biomed Eng. 2024 Jul 24; 9:e54631.View Related Profiles. PMID: 39047284; PMCID: PMC11306942; DOI: 10.2196/54631;
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Grech J, Nkambule BB, Thibord F, Chan MV, Lachapelle AR, Vasan R, Spartano NL, Chen MH, Nayor M, Lewis GD, Johnson AD. Cardiorespiratory Fitness Is Associated with Decreased Platelet Reactivity. Med Sci Sports Exerc. 2024 Nov 01; 56(11):2195-2202.View Related Profiles. PMID: 38913957
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Zhang Y, Wang X, Pathiravasan CH, Spartano NL, Lin H, Borrelli B, Benjamin EJ, McManus DD, Larson MG, Vasan RS, Shah RV, Lewis GD, Liu C, Murabito JM, Nayor M. Association of Smartwatch-Based Heart Rate and Physical Activity With Cardiorespiratory Fitness Measures in the Community: Cohort Study. J Med Internet Res. 2024 Jun 13; 26:e56676.View Related Profiles. PMID: 38870519; PMCID: PMC11216017; DOI: 10.2196/56676;
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Alver SK, Pan S, Mossavar-Rahmani Y, Sotres-Alvarez D, Evenson KR, Floyd JS, Xanthakis V, Lin J, Cuthbertson C, Gallo LC, Cai J, Penedo FJ, Llabre MM, Matsushita K, Talavera GA, Pirzada A, Spartano N, Daviglus ML, Vasan RS, Kaplan RC. Physical Activity, Cardiovascular Status, Mortality, and Prediabetes in Hispanic and Non-Hispanic Adults. JAMA Netw Open. 2024 Jun 03; 7(6):e2415094.View Related Profiles. PMID: 38842811; PMCID: PMC11157354; DOI: 10.1001/jamanetworkopen.2024.15094;
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Gonzales MM, Kojis D, Spartano NL, Thibault EG, DeCarli CS, El Fakhri G, Johnson KA, Beiser AS, Seshadri S. Associations of Physical Activity Engagement with Cerebral Amyloid-ß and Tau from Midlife. J Alzheimers Dis. 2024; 100(3):935-943.View Related Profiles. PMID: 39031362
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Mossavar-Rahmani Y, Lin J, Pan S, Song RJ, Xue X, Spartano NL, Xanthakis V, Sotres-Alvarez D, Marquez DX, Daviglus M, Carlson JA, Parada H, Evenson KR, Talavera AC, Gellman M, Perreira KM, Gallo LC, Vasan RS, Kaplan RC. Characterizing longitudinal change in accelerometry-based moderate-to-vigorous physical activity in the Hispanic Community Health Study/Study of Latinos and the Framingham Heart Study. BMC Public Health. 2023 Aug 24; 23(1):1614.View Related Profiles. PMID: 37620824; PMCID: PMC10464120; DOI: 10.1186/s12889-023-16442-9;
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Wang X, Pathiravasan CH, Zhang Y, Trinquart L, Borrelli B, Spartano NL, Lin H, Nowak C, Kheterpal V, Benjamin EJ, McManus DD, Murabito JM, Liu C. Association of Depressive Symptom Trajectory With Physical Activity Collected by mHealth Devices in the Electronic Framingham Heart Study: Cohort Study. JMIR Ment Health. 2023 Jul 14; 10:e44529.View Related Profiles. PMID: 37450333; PMCID: PMC10382951; DOI: 10.2196/44529;
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Perry AS, Dooley EE, Master H, Spartano NL, Brittain EL, Pettee Gabriel K. Physical Activity Over the Lifecourse and Cardiovascular Disease. Circ Res. 2023 Jun 09; 132(12):1725-1740. PMID: 37289900; PMCID: PMC10254078; DOI: 10.1161/CIRCRESAHA.123.322121;
Showing 10 of 68 results.
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Shapira-Daniels A, Kornej J, Spartano NL, Wang X, Zhang Y, Pathiravasan CH, Liu C, Trinquart L, Borrelli B, McManus DD, Murabito JM, Benjamin EJ, Lin H. Step Count, Self-reported Physical Activity, and Predicted 5-Year Risk of Atrial Fibrillation: Cross-sectional Analysis. J Med Internet Res. 2023 Mar 06; 25:e43123.View Related Profiles. PMID: 36877540; PMCID: PMC10028513; DOI: 10.2196/43123;
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Trinquart L, Liu C, McManus DD, Nowak C, Lin H, Spartano NL, Borrelli B, Benjamin EJ, Murabito JM. Increasing Engagement in the Electronic Framingham Heart Study: Factorial Randomized Controlled Trial. J Med Internet Res. 2023 Jan 20; 25:e40784.View Related Profiles. PMID: 36662544; PMCID: PMC9898831; DOI: 10.2196/40784;
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Spartano NL, Wang R, Yang Q, Chernofsky A, Murabito JM, Levy D, Vasan RS, DeCarli C, Maillard P, Seshadri S, Beiser AS. Association of Physical Inactivity with MRI Markers of Brain Aging: Assessing Mediation by Cardiometabolic and Epigenetic Factors. J Alzheimers Dis. 2023; 95(2):561-572.View Related Profiles. PMID: 37574733
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Pathiravasan CH, Zhang Y, Wang X, Trinquart L, Benjamin EJ, Borrelli B, McManus DD, Kheterpal V, Lin H, Spartano NL, Schramm E, Liu C, Murabito JM. Factors associated with long-term use of digital devices in the electronic Framingham Heart Study. NPJ Digit Med. 2022 Dec 27; 5(1):195.View Related Profiles. PMID: 36572707; PMCID: PMC9792462; DOI: 10.1038/s41746-022-00735-1;
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Paluch AE, Bajpai S, Ballin M, Bassett DR, Buford TW, Carnethon MR, Chernofsky A, Dooley EE, Ekelund U, Evenson KR, Galuska DA, Jefferis BJ, Kong L, Kraus WE, Larson MG, Lee IM, Matthews CE, Newton RL, Nordström A, Nordström P, Palta P, Patel AV, Pettee Gabriel K, Pieper CF, Pompeii L, Rees-Punia E, Spartano NL, Vasan RS, Whincup PH, Yang S, Fulton JE. Prospective Association of Daily Steps With Cardiovascular Disease: A Harmonized Meta-Analysis. Circulation. 2023 Jan 10; 147(2):122-131.View Related Profiles. PMID: 36537288; PMCID: PMC9839547; DOI: 10.1161/CIRCULATIONAHA.122.061288;
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Spartano NL, Wang R, Yang Q, Chernofsky A, Murabito JM, Vasan RS, Levy D, Beiser AS, Seshadri S. Association of Accelerometer-Measured Physical Activity and Sedentary Time with Epigenetic Markers of Aging. Med Sci Sports Exerc. 2023 Feb 01; 55(2):264-272.View Related Profiles. PMID: 36107108; PMCID: PMC9840651; DOI: 10.1249/MSS.0000000000003041;
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Walker ME, Spartano NL. Identifying Ultraprocessed Foods in Nutrition Research: What a Process! Neurology. 2022 Sep 06; 99(10):411-412.View Related Profiles. PMID: 36219799
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Walker ME, Spartano NL. Identifying Ultra-processed Foods in Nutrition Research: What a Proccess! Neurology. 2022 Jul 27.View Related Profiles. PMID: 35896435
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Almohamad M, Krall Kaye E, Mofleh D, Spartano NL. The association of sedentary behaviour and physical activity with periodontal disease in NHANES 2011-2012. J Clin Periodontol. 2022 Aug; 49(8):758-767. PMID: 35634657
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Kaplan RC, Song RJ, Lin J, Xanthakis V, Hua S, Chernofsky A, Evenson KR, Walker ME, Cuthbertson C, Murabito JM, Cordero C, Daviglus M, Perreira KM, Gellman M, Sotres-Alvarez D, Vasan RS, Xue X, Spartano NL, Mossavar-Rahmani Y. Predictors of incident diabetes in two populations: framingham heart study and hispanic community health study / study of latinos. BMC Public Health. 2022 May 26; 22(1):1053.View Related Profiles. PMID: 35619100; PMCID: PMC9137165; DOI: 10.1186/s12889-022-13463-8;
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Nayor M, Chernofsky A, Miller PE, Spartano NL, Murthy VL, Malhotra R, Houstis NE, Murabito JM, Clish CB, Larson MG, Vasan RS, Shah RV, Lewis GD. Integrative Analysis of Circulating Metabolite Levels That Correlate With Physical Activity and Cardiorespiratory Fitness. Circ Genom Precis Med. 2022 Jun; 15(3):e003592.View Related Profiles. PMID: 35536222; PMCID: PMC9233103; DOI: 10.1161/CIRCGEN.121.003592;
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Hammond MM, Zhang Y, Pathiravasan CH, Lin H, Sardana M, Trinquart L, Benjamin EJ, Borrelli B, Manders ES, Fusco K, Kornej J, Spartano NL, Kheterpal V, Nowak C, McManus DD, Liu C, Murabito JM. Relations Between BMI Trajectories and Habitual Physical Activity Measured by a Smartwatch in the Electronic Cohort of the Framingham Heart Study: Cohort Study. JMIR Cardio. 2022 Apr 27; 6(1):e32348.View Related Profiles. PMID: 35476038; PMCID: PMC9096636; DOI: 10.2196/32348;
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Paluch AE, Bajpai S, Bassett DR, Carnethon MR, Ekelund U, Evenson KR, Galuska DA, Jefferis BJ, Kraus WE, Lee IM, Matthews CE, Omura JD, Patel AV, Pieper CF, Rees-Punia E, Dallmeier D, Klenk J, Whincup PH, Dooley EE, Pettee Gabriel K, Palta P, Pompeii LA, Chernofsky A, Larson MG, Vasan RS, Spartano N, Ballin M, Nordström P, Nordström A, Anderssen SA, Hansen BH, Cochrane JA, Dwyer T, Wang J, Ferrucci L, Liu F, Schrack J, Urbanek J, Saint-Maurice PF, Yamamoto N, Yoshitake Y, Newton RL, Yang S, Shiroma EJ, Fulton JE. Daily steps and all-cause mortality: a meta-analysis of 15 international cohorts. Lancet Public Health. 2022 03; 7(3):e219-e228.View Related Profiles. PMID: 35247352; PMCID: PMC9289978; DOI: 10.1016/S2468-2667(21)00302-9;
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Zhang Y, Pathiravasan CH, Hammond MM, Liu H, Lin H, Sardana M, Trinquart L, Borrelli B, Manders ES, Kornej J, Spartano NL, Nowak C, Kheterpal V, Benjamin EJ, McManus DD, Murabito JM, Liu C. Comparison of Daily Routines Between Middle-aged and Older Participants With and Those Without Diabetes in the Electronic Framingham Heart Study: Cohort Study. JMIR Diabetes. 2022 Jan 07; 7(1):e29107.View Related Profiles. PMID: 34994694; PMCID: PMC8783285; DOI: 10.2196/29107;
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Trethewey RE, Spartano NL, Vasan RS, Larson MG, O'Connor GT, Esliger DW, Petherick ES, Steiner MC. Body mass index across adulthood and the development of airflow obstruction and emphysema. Chron Respir Dis. 2022; 19:14799731221139294.View Related Profiles. PMID: 36351077; PMCID: PMC9661572; DOI: 10.1177/14799731221139294;
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Spartano NL, Himali JJ, Trinquart L, Yang Q, Weinstein G, Satizabal CL, Dukes KA, Beiser AS, Murabito JM, Vasan RS, Seshadri S. Accelerometer-Measured, Habitual Physical Activity and Circulating Brain-Derived Neurotrophic Factor: A Cross-Sectional Study. J Alzheimers Dis. 2022; 85(2):805-814.View Related Profiles. PMID: 34864673; DOI: 10.3233/JAD-215109;
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Tarp J, Fagerland MW, Dalene KE, Johannessen JS, Hansen BH, Jefferis BJ, Whincup PH, Diaz KM, Hooker S, Howard VJ, Chernofsky A, Larson MG, Spartano NL, Vasan RS, Dohrn IM, Hagströmer M, Edwardson C, Yates T, Shiroma EJ, Dempsey PC, Wijndaele K, Anderssen SA, Lee IM, Ekelund U. Device-measured physical activity, adiposity and mortality: a harmonised meta-analysis of eight prospective cohort studies. Br J Sports Med. 2022 Jul; 56(13):725-732.View Related Profiles. PMID: 34876405; PMCID: PMC9209690; DOI: 10.1136/bjsports-2021-104827;
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Kornej J, Murabito JM, Zhang Y, Liu C, Trinquart L, Sardana M, Manders ES, Hammond MM, Spartano NL, Pathiravasan CH, Wang X, Borrelli B, McManus DD, Benjamin EJ, Lin H. No evidence of association between habitual physical activity and ECG traits: Insights from the electronic Framingham Heart Study. Cardiovasc Digit Health J. 2022 Feb; 3(1):56-58.View Related Profiles. PMID: 35265935; PMCID: PMC8890067; DOI: 10.1016/j.cvdhj.2021.11.004;
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Nayor M, Chernofsky A, Spartano NL, Tanguay M, Blodgett JB, Murthy VL, Malhotra R, Houstis NE, Velagaleti RS, Murabito JM, Larson MG, Vasan RS, Shah RV, Lewis GD. Physical activity and fitness in the community: the Framingham Heart Study. Eur Heart J. 2021 11 21; 42(44):4565-4575.View Related Profiles. PMID: 34436560; PMCID: PMC8633734; DOI: 10.1093/eurheartj/ehab580;
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Spartano NL. What Are the Next Steps for Developing a National Steps Guideline? JAMA Netw Open. 2021 09 01; 4(9):e2125267. PMID: 34477855
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Sardana M, Lin H, Zhang Y, Liu C, Trinquart L, Benjamin EJ, Manders ES, Fusco K, Kornej J, Hammond MM, Spartano N, Pathiravasan CH, Kheterpal V, Nowak C, Borrelli B, Murabito JM, McManus DD. Association of Habitual Physical Activity With Home Blood Pressure in the Electronic Framingham Heart Study (eFHS): Cross-sectional Study. J Med Internet Res. 2021 06 24; 23(6):e25591.View Related Profiles. PMID: 34185019; PMCID: PMC8277303; DOI: 10.2196/25591;
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Barone Gibbs B, Hivert MF, Jerome GJ, Kraus WE, Rosenkranz SK, Schorr EN, Spartano NL, Lobelo F. Physical Activity as a Critical Component of First-Line Treatment for Elevated Blood Pressure or Cholesterol: Who, What, and How?: A Scientific Statement From the American Heart Association. Hypertension. 2021 08; 78(2):e26-e37. PMID: 34074137
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Lee J, Walker ME, Bourdillon MT, Spartano NL, Rogers GT, Jacques PF, Vasan RS, Xanthakis V. Conjoint Associations of Adherence to Physical Activity and Dietary Guidelines With Cardiometabolic Health: The Framingham Heart Study. J Am Heart Assoc. 2021 04 06; 10(7):e019800.View Related Profiles. PMID: 33784828; PMCID: PMC8174320; DOI: 10.1161/JAHA.120.019800;
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Pathiravasan CH, Zhang Y, Trinquart L, Benjamin EJ, Borrelli B, McManus DD, Kheterpal V, Lin H, Sardana M, Hammond MM, Spartano NL, Dunn AL, Schramm E, Nowak C, Manders ES, Liu H, Kornej J, Liu C, Murabito JM. Adherence of Mobile App-Based Surveys and Comparison With Traditional Surveys: eCohort Study. J Med Internet Res. 2021 01 20; 23(1):e24773.View Related Profiles. PMID: 33470944; PMCID: PMC7857942; DOI: 10.2196/24773;
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Spartano NL, Pantoni L. What Can Longitudinal Observational Studies of Physical Activity Teach Us About Prevention of Dementia? Neurology. 2021 02 16; 96(7):297-298. PMID: 33408143
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Ekelund U, Tarp J, Fagerland MW, Johannessen JS, Hansen BH, Jefferis BJ, Whincup PH, Diaz KM, Hooker S, Howard VJ, Chernofsky A, Larson MG, Spartano N, Vasan RS, Dohrn IM, Hagströmer M, Edwardson C, Yates T, Shiroma EJ, Dempsey P, Wijndaele K, Anderssen SA, Lee IM. Joint associations of accelero-meter measured physical activity and sedentary time with all-cause mortality: a harmonised meta-analysis in more than 44 000 middle-aged and older individuals. Br J Sports Med. 2020 Dec; 54(24):1499-1506.View Related Profiles. PMID: 33239356; PMCID: PMC7719907; DOI: 10.1136/bjsports-2020-103270;
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Chen GC, Qi Q, Hua S, Moon JY, Spartano NL, Vasan RS, Sotres-Alvarez D, Castaneda SF, Evenson KR, Perreira KM, Gallo LC, Pirzada A, Diaz KM, Daviglus ML, Gellman MD, Kaplan RC, Xue X, Mossavar-Rahmani Y. Accelerometer-assessed physical activity and incident diabetes in a population covering the adult life span: the Hispanic Community Health Study/Study of Latinos. Am J Clin Nutr. 2020 11 11; 112(5):1318-1327. PMID: 32910816; PMCID: PMC7657343; DOI: 10.1093/ajcn/nqaa232;
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Lin H, Sardana M, Zhang Y, Liu C, Trinquart L, Benjamin EJ, Manders ES, Fusco K, Kornej J, Hammond MM, Spartano NL, Pathiravasan CH, Kheterpal V, Nowak C, Borrelli B, Murabito JM, McManus DD. Association of Habitual Physical Activity With Cardiovascular Disease Risk. Circ Res. 2020 10 23; 127(10):1253-1260.View Related Profiles. PMID: 32842915; PMCID: PMC7581630; DOI: 10.1161/CIRCRESAHA.120.317578;
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Lin HP, Lynk N, Moore LL, Cabral HJ, Heffernan KS, Dumas AK, Hruska B, Zajdel RA, Gump BB, Spartano NL. A pragmatic approach to the comparison of wrist-based cutpoints of physical activity intensity for the MotionWatch8 accelerometer in children. PLoS One. 2020; 15(6):e0234725.View Related Profiles. PMID: 32559207; PMCID: PMC7304605; DOI: 10.1371/journal.pone.0234725;
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Lefferts WK, Augustine JA, Spartano NL, Hughes WE, Babcock MC, Heenan BK, Heffernan KS. Effects of Whey Protein Supplementation on Aortic Stiffness, Cerebral Blood Flow, and Cognitive Function in Community-Dwelling Older Adults: Findings from the ANCHORS A-WHEY Clinical Trial. Nutrients. 2020 Apr 10; 12(4). PMID: 32290271; PMCID: PMC7230701; DOI: 10.3390/nu12041054;
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Virani SS, Alonso A, Benjamin EJ, Bittencourt MS, Callaway CW, Carson AP, Chamberlain AM, Chang AR, Cheng S, Delling FN, Djousse L, Elkind MSV, Ferguson JF, Fornage M, Khan SS, Kissela BM, Knutson KL, Kwan TW, Lackland DT, Lewis TT, Lichtman JH, Longenecker CT, Loop MS, Lutsey PL, Martin SS, Matsushita K, Moran AE, Mussolino ME, Perak AM, Rosamond WD, Roth GA, Sampson UKA, Satou GM, Schroeder EB, Shah SH, Shay CM, Spartano NL, Stokes A, Tirschwell DL, VanWagner LB, Tsao CW. Heart Disease and Stroke Statistics-2020 Update: A Report From the American Heart Association. Circulation. 2020 03 03; 141(9):e139-e596.View Related Profiles. PMID: 31992061
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Spartano NL, Demissie S, Himali JJ, Dukes KA, Murabito JM, Vasan RS, Beiser AS, Seshadri S. Accelerometer-determined physical activity and cognitive function in middle-aged and older adults from two generations of the Framingham Heart Study. Alzheimers Dement (N Y). 2019; 5:618-626.View Related Profiles. PMID: 31660424; PMCID: PMC6807299; DOI: 10.1016/j.trci.2019.08.007;
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Spartano NL, Lin H, Sun F, Lunetta KL, Trinquart L, Valentino M, Manders ES, Pletcher MJ, Marcus GM, McManus DD, Benjamin EJ, Fox CS, Olgin JE, Murabito JM. Comparison of On-Site Versus Remote Mobile Device Support in the Framingham Heart Study Using the Health eHeart Study for Digital Follow-up: Randomized Pilot Study Set Within an Observational Study Design. JMIR Mhealth Uhealth. 2019 09 30; 7(9):e13238.View Related Profiles. PMID: 31573928; PMCID: PMC6792023; DOI: 10.2196/13238;
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Ekelund U, Tarp J, Steene-Johannessen J, Hansen BH, Jefferis B, Fagerland MW, Whincup P, Diaz KM, Hooker SP, Chernofsky A, Larson MG, Spartano N, Vasan RS, Dohrn IM, Hagströmer M, Edwardson C, Yates T, Shiroma E, Anderssen SA, Lee IM. Dose-response associations between accelerometry measured physical activity and sedentary time and all cause mortality: systematic review and harmonised meta-analysis. BMJ. 2019 08 21; 366:l4570.View Related Profiles. PMID: 31434697; PMCID: PMC6699591; DOI: 10.1136/bmj.l4570;
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Spartano NL, Davis-Plourde KL, Himali JJ, Andersson C, Pase MP, Maillard P, DeCarli C, Murabito JM, Beiser AS, Vasan RS, Seshadri S. Association of Accelerometer-Measured Light-Intensity Physical Activity With Brain Volume: The Framingham Heart Study. JAMA Netw Open. 2019 04 05; 2(4):e192745.View Related Profiles. PMID: 31002329; PMCID: PMC6481600; DOI: 10.1001/jamanetworkopen.2019.2745;
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Benjamin EJ, Muntner P, Alonso A, Bittencourt MS, Callaway CW, Carson AP, Chamberlain AM, Chang AR, Cheng S, Das SR, Delling FN, Djousse L, Elkind MSV, Ferguson JF, Fornage M, Jordan LC, Khan SS, Kissela BM, Knutson KL, Kwan TW, Lackland DT, Lewis TT, Lichtman JH, Longenecker CT, Loop MS, Lutsey PL, Martin SS, Matsushita K, Moran AE, Mussolino ME, O'Flaherty M, Pandey A, Perak AM, Rosamond WD, Roth GA, Sampson UKA, Satou GM, Schroeder EB, Shah SH, Spartano NL, Stokes A, Tirschwell DL, Tsao CW, Turakhia MP, VanWagner LB, Wilkins JT, Wong SS, Virani SS. Heart Disease and Stroke Statistics-2019 Update: A Report From the American Heart Association. Circulation. 2019 03 05; 139(10):e56-e528.View Related Profiles. PMID: 30700139
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McManus DD, Trinquart L, Benjamin EJ, Manders ES, Fusco K, Jung LS, Spartano NL, Kheterpal V, Nowak C, Sardana M, Murabito JM. Design and Preliminary Findings From a New Electronic Cohort Embedded in the Framingham Heart Study. J Med Internet Res. 2019 03 01; 21(3):e12143.View Related Profiles. PMID: 30821691; PMCID: PMC6418484; DOI: 10.2196/12143;
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Spartano NL, Davis-Plourde KL, Himali JJ, Murabito JM, Vasan RS, Beiser AS, Seshadri S. Self-Reported Physical Activity and Relations to Growth and Neurotrophic Factors in Diabetes Mellitus: The Framingham Offspring Study. J Diabetes Res. 2019; 2019:2718465.View Related Profiles. PMID: 30729134; PMCID: PMC6343169; DOI: 10.1155/2019/2718465;
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Riffenburg KM, Spartano NL. Physical activity and weight maintenance: the utility of wearable devices and mobile health technology in research and clinical settings. Curr Opin Endocrinol Diabetes Obes. 2018 10; 25(5):310-314. PMID: 30063553
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Spartano NL, Bernhardt J. Prestroke physical activity to reduce stroke severity: Moving to lower risk with light activity. Neurology. 2018 10 16; 91(16):727-728. PMID: 30232247
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Spartano NL, Ngandu T. Fitness and dementia risk: Further evidence of the heart-brain connection. Neurology. 2018 04 10; 90(15):675-676. PMID: 29540586
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Benjamin EJ, Virani SS, Callaway CW, Chamberlain AM, Chang AR, Cheng S, Chiuve SE, Cushman M, Delling FN, Deo R, de Ferranti SD, Ferguson JF, Fornage M, Gillespie C, Isasi CR, Jiménez MC, Jordan LC, Judd SE, Lackland D, Lichtman JH, Lisabeth L, Liu S, Longenecker CT, Lutsey PL, Mackey JS, Matchar DB, Matsushita K, Mussolino ME, Nasir K, O'Flaherty M, Palaniappan LP, Pandey A, Pandey DK, Reeves MJ, Ritchey MD, Rodriguez CJ, Roth GA, Rosamond WD, Sampson UKA, Satou GM, Shah SH, Spartano NL, Tirschwell DL, Tsao CW, Voeks JH, Willey JZ, Wilkins JT, Wu JH, Alger HM, Wong SS, Muntner P. Heart Disease and Stroke Statistics-2018 Update: A Report From the American Heart Association. Circulation. 2018 03 20; 137(12):e67-e492.View Related Profiles. PMID: 29386200
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Heffernan KS, Augustine JA, Lefferts WK, Spartano NL, Hughes WE, Jorgensen RS, Gump BB. Arterial stiffness and cerebral hemodynamic pulsatility during cognitive engagement in younger and older adults. Exp Gerontol. 2018 01; 101:54-62. PMID: 29129735; DOI: 10.1016/j.exger.2017.11.004;
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Spartano NL, Stevenson MD, Xanthakis V, Larson MG, Andersson C, Murabito JM, Vasan RS. Associations of objective physical activity with insulin sensitivity and circulating adipokine profile: the Framingham Heart Study. Clin Obes. 2017 Apr; 7(2):59-69.View Related Profiles. PMID: 28112860; PMCID: PMC5339058; DOI: 10.1111/cob.12177;
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Lefferts WK, Augustine JA, Spartano NL, Atallah-Yunes NH, Heffernan KS, Gump BB. Racial differences in central hemodynamics and subclinical markers of cardiovascular disease risk in children. Journal of Pediatrics. 2017; 180:62-67.
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Spartano NL, Heffernan KS, Dumas AK, Gump BB. Accelerometer-determined physical activity and the cardiovascular response to mental stress in children. J Sci Med Sport. 2017 Jan; 20(1):60-65. PMID: 27283342; PMCID: PMC5133178; DOI: 10.1016/j.jsams.2016.05.008;
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Andersson C, Lyass A, Larson MG, Spartano NL, Vita JA, Benjamin EJ, Murabito JM, Esliger DW, Blease SJ, Hamburg NM, Mitchell GF, Vasan RS. Physical activity measured by accelerometry and its associations with cardiac structure and vascular function in young and middle-aged adults. J Am Heart Assoc. 2015 Mar; 4(3):e001528.View Related Profiles. PMID: 25792127; PMCID: PMC4392434; DOI: 10.1161/JAHA.114.001528;
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Heffernan KS, Spartano NL, Augustine JA, Lefferts WK, Hughes WE, Mitchell GF, Jorgensen RS, Gump BB. Carotid artery stiffness and hemodynamic pulsatility during cognitive engagement in healthy adults: a pilot investigation. Am J Hypertens. 2015 May; 28(5):615-22. PMID: 25384407; PMCID: PMC4462651; DOI: 10.1093/ajh/hpu198;
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Hughes WE, Spartano NL, Augustine JA, Lefferts WK, Heffernan KS. Sex differences in noninvasive estimates of left ventricular pressure energetics but not myocardial oxygen demand in young adults. Artery Research. 2014; 197-204.
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Spartano NL, Lamon-Fava S, Matthan NR, Ronxhi J, Greenberg AS, Obin MS, Lichtenstein AH. Regulation of ATP-binding cassette transporters and cholesterol efflux by glucose in primary human monocytes and murine bone marrow-derived macrophages. Exp Clin Endocrinol Diabetes. 2014 Sep; 122(8):463-8. PMID: 24838154; PMCID: PMC4279857; DOI: 10.1055/s-0034-1374600;
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Spartano NL, Lamon-Fava S, Matthan NR, Obin MS, Greenberg AS, Lichtenstein AH. Linoleic acid suppresses cholesterol efflux and ATP-binding cassette transporters in murine bone marrow-derived macrophages. Lipids. 2014 May; 49(5):415-22. PMID: 24595513; PMCID: PMC4009986; DOI: 10.1007/s11745-014-3890-y;
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Spartano NL, Augustine JA, Lefferts WK, Hughes WE, Redmond JG, Martin ED, Gump BB, Kuvin JT, Heffernan KS. Current Biomarker Findings. Arterial stiffness as a non-invasive tissue biomarker of cardiac target organ damage. Dove Medical Press. Auckland. 2014; 4:23-34.
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Spartano NL, Augustine JA, Lefferts WK, Gump BB, Heffernan KS. Atherosclerosis. Carotid blood pressure reactivity to mental stress predicts carotid intima-media thickness. Elsevier. Amsterdam. 2014; 236(2):227-229.
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Dillard A, Matthan NR, Spartano NL, Butkowski AE, Lichtenstein AH. Background diet and fat type alters plasma lipoprotein response but not aortic cholesterol accumulation in F1B Golden Syrian hamsters. Lipids. 2013 Dec; 48(12):1177-84. PMID: 24096944
This graph shows the total number of publications by year, by first, middle/unknown,
or last author.
| Year | Publications |
|---|
| 2013 | 1 |
| 2014 | 6 |
| 2015 | 1 |
| 2016 | 3 |
| 2017 | 4 |
| 2018 | 4 |
| 2019 | 8 |
| 2020 | 6 |
| 2021 | 9 |
| 2022 | 13 |
| 2023 | 6 |
| 2024 | 7 |
Dr. Nicole Spartano - Neurology Study
2018 American Heart Association:
Sandra A. Daugherty Award, Finalist
2017 American Heart Association Specialty Conferences :
Best of American Heart Association Specialty Conferences
2016 American Heart Association:
Early Investigator Travel Award
2015 American Heart Association Specialty Conferences:
Best of American Heart Association Specialty Conferences
2015 Boston University Professional Development & Postdoctoral Affairs:
Travel Award
2014-2016 NIH/NHLBI:
Postdoctoral Training Grant award
2009-2012 NIH/NHLBI:
Pre-doctoral Training Grant award
2007-2009 Tufts University:
Friedman School of Nutrition Scholarship
2006 Syracuse University:
Biology Award for Research Excellence