Nicole Spartano | Profiles RNS

Nicole Spartano, PhD

Assistant Professor

Boston University Chobanian & Avedisian School of Medicine

Medicine

Endocrinology, Diabetes, Nutrition & Weight Management

PhD, Tufts University
MS, Tufts University
BS, Syracuse University

Websites

ResearchGate

ORCID : 0000-0002-0724-8629

Nicole Spartano, PhD is an Assistant Professor of Medicine in Endocrinology, Diabetes, Nutrition and Weight Management at the Chobanian and Avedisian School of Medicine. She serves as the Director of the Glucose Monitoring Station at the Framingham Heart Study. This study is funded through an R01 from the National Institute of Diabetes and Digestive and Kidney Diseases (Spartano, PI) to use continuous glucose monitors in a non-diabetic population to measure glucose patterns that may predict the development of diabetes. She also serves as the Co-Director of the Physical Activity Station at the Framingham Heart Study, overseeing data collection using accelerometers (fitness trackers). She has received funding from the American Heart Association and Alzheimer's Association to understand the impact of physical activity throughout the lifecourse on brain health and the risk for dementia and Alzheimer's disease.

Dr. Spartano also has a major research interest in using mobile health technology to improve health in underserved patient populations at Boston Medical Center. She is exploring the use of continuous glucose monitors as a tool for enhancing lifestyle interventions in patients with and without diabetes mellitus. She shares a MPI role on a Focused Research Project funded by Boston University’s Hariri Institute, which facilitates collaborations of clinical and computational investigators. This team is developing a software platform that can continuously collect mobile health data from research participants and patients. The goal of creating this platform is to address challenges in privacy and in providing timely communication to medically vulnerable patients.

Dr. Spartano also teaches courses for Boston University Graduate Medical Sciences, School of Public Health, and Sargent College of Health Sciences.

Investigator
Framingham Heart Study

Member
Boston University
Evans Center for Interdisciplinary Biomedical Research

Graduate Faculty (Primary Mentor of Grad Students)
Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences

BU Research
BMC Research

Continuous glucose monitoring: determinants and prediction of diabetes mellitus development in the Framingham Heart Study
04/01/2022 - 03/31/2027 (PI)
NIH/National Diabetes & Digestive & Kidney Diseases
5R01DK129305-03

The Longitudinal Influence of Midlife Physical Activity and Sedentary Time on Vascular Brain Injury
07/01/2016 - 06/30/2019 (PI)
American Heart Association

Massachusetts AI and Technology Center for Connected Care in Aging and Alzheimer's Disease
09/01/2023 - 05/31/2025 (Subcontract PI)
PI: Nicole Spartano, PhD
University of Massachusetts / UMASS NIH NIA

Physical Inactivity, Epigenetic Aging, and Preclinical Dementia
12/01/2020 - 05/31/2022 (PI)
Alzheimer’s Association

Title

Yr	Title	Project-Sub Proj	Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Alexanian SM, Cheney MC, Spartano NL, Bello-Ramos JC, Reddy N, Malik A, Murati J, Wolpert HA, Steenkamp DW. Comparing Postprandial Glycemic Control Using Fiasp vs Insulin Aspart in Hospitalized Patients With Type 2 Diabetes. Endocr Pract. 2024 Dec 04.View Related Profiles.

Steenkamp, Devin
Wolpert, Howard
Cheney, Michael
Spartano, Nicole
Alexanian, Sara

PMID: 39643003; DOI: 10.1016/j.eprac.2024.11.015;

Klonoff DC, Freckmann G, Pleus S, Kovatchev BP, Kerr D, Tse CC, Li C, Agus MSD, Dungan K, Voglová Hagerf B, Krouwer JS, Lee WA, Misra S, Rhee SY, Sabharwal A, Seley JJ, Shah VN, Tran NK, Waki K, Worth C, Tian T, Aaron RE, Rutledge K, Ho CN, Ayers AT, Adler A, Ahn DT, Aktürk HK, Al-Sofiani ME, Bailey TS, Baker M, Bally L, Bannuru RR, Bauer EM, Bee YM, Blanchette JE, Cengiz E, Chase JG, Y Chen K, Cherñavvsky D, Clements M, Cote GL, Dhatariya KK, Drincic A, Ejskjaer N, Espinoza J, Fabris C, Fleming GA, Gabbay MAL, Galindo RJ, Gómez-Medina AM, Heinemann L, Hermanns N, Hoang T, Hussain S, Jacobs PG, Jendle J, Joshi SR, Koliwad SK, Lal RA, Leiter LA, Lind M, Mader JK, Maran A, Masharani U, Mathioudakis N, McShane M, Mehta C, Moon SJ, Nichols JH, O'Neal DN, Pasquel FJ, Peters AL, Pfützner A, Pop-Busui R, Ranjitkar P, Rhee CM, Sacks DB, Schmidt S, Schwaighofer SM, Sheng B, Simonson GD, Sode K, Spanakis EK, Spartano NL, Umpierrez GE, Vareth M, Vesper HW, Wang J, Wright E, Wu AHB, Yeshiwas S, Zilbermint M, Kohn MA. The Diabetes Technology Society Error Grid and Trend Accuracy Matrix for Glucose Monitors. J Diabetes Sci Technol. 2024 Nov; 18(6):1346-1361. PMID: 39369312; PMCID: PMC11531029; DOI: 10.1177/19322968241275701;

Spartano NL, Sultana N, Lin H, Cheng H, Lu S, Fei D, Murabito JM, Walker ME, Wolpert HA, Steenkamp DW. Defining continuous glucose monitor time in range in a large community-based cohort without diabetes. J Clin Endocrinol Metab. 2024 Sep 11.View Related Profiles.

Steenkamp, Devin
Lin, Honghuang
Wolpert, Howard
Cheng, Huimin
Murabito, Joanne
Walker, Maura
Spartano, Nicole

PMID: 39257191; DOI: 10.1210/clinem/dgae626;

Spartano NL, Zhang Y, Liu C, Chernofsky A, Lin H, Trinquart L, Borrelli B, Pathiravasan CH, Kheterpal V, Nowak C, Vasan RS, Benjamin EJ, McManus DD, Murabito JM. Agreement Between Apple Watch and Actical Step Counts in a Community Setting: Cross-Sectional Investigation From the Framingham Heart Study. JMIR Biomed Eng. 2024 Jul 24; 9:e54631.View Related Profiles.

Borrelli, Belinda
Pathiravasan, Chathurangi
Liu, Chunyu
Benjamin, Emelia
Lin, Honghuang
Murabito, Joanne
Trinquart, Ludovic
Spartano, Nicole

PMID: 39047284; PMCID: PMC11306942; DOI: 10.2196/54631;

Grech J, Nkambule BB, Thibord F, Chan MV, Lachapelle AR, Vasan R, Spartano NL, Chen MH, Nayor M, Lewis GD, Johnson AD. Cardiorespiratory Fitness Is Associated with Decreased Platelet Reactivity. Med Sci Sports Exerc. 2024 Nov 01; 56(11):2195-2202.View Related Profiles.

Nayor, Matthew
Spartano, Nicole

PMID: 38913957

Zhang Y, Wang X, Pathiravasan CH, Spartano NL, Lin H, Borrelli B, Benjamin EJ, McManus DD, Larson MG, Vasan RS, Shah RV, Lewis GD, Liu C, Murabito JM, Nayor M. Association of Smartwatch-Based Heart Rate and Physical Activity With Cardiorespiratory Fitness Measures in the Community: Cohort Study. J Med Internet Res. 2024 Jun 13; 26:e56676.View Related Profiles.

Borrelli, Belinda
Pathiravasan, Chathurangi
Liu, Chunyu
Benjamin, Emelia
Lin, Honghuang
Murabito, Joanne
Larson, Martin
Nayor, Matthew
Spartano, Nicole

PMID: 38870519; PMCID: PMC11216017; DOI: 10.2196/56676;

Alver SK, Pan S, Mossavar-Rahmani Y, Sotres-Alvarez D, Evenson KR, Floyd JS, Xanthakis V, Lin J, Cuthbertson C, Gallo LC, Cai J, Penedo FJ, Llabre MM, Matsushita K, Talavera GA, Pirzada A, Spartano N, Daviglus ML, Vasan RS, Kaplan RC. Physical Activity, Cardiovascular Status, Mortality, and Prediabetes in Hispanic and Non-Hispanic Adults. JAMA Netw Open. 2024 Jun 03; 7(6):e2415094.View Related Profiles.

Spartano, Nicole
Xanthakis, Vanessa

PMID: 38842811; PMCID: PMC11157354; DOI: 10.1001/jamanetworkopen.2024.15094;

Gonzales MM, Kojis D, Spartano NL, Thibault EG, DeCarli CS, El Fakhri G, Johnson KA, Beiser AS, Seshadri S. Associations of Physical Activity Engagement with Cerebral Amyloid-ß and Tau from Midlife. J Alzheimers Dis. 2024; 100(3):935-943.View Related Profiles.

Beiser, Alexa
Spartano, Nicole
Seshadri, Sudha

PMID: 39031362

Mossavar-Rahmani Y, Lin J, Pan S, Song RJ, Xue X, Spartano NL, Xanthakis V, Sotres-Alvarez D, Marquez DX, Daviglus M, Carlson JA, Parada H, Evenson KR, Talavera AC, Gellman M, Perreira KM, Gallo LC, Vasan RS, Kaplan RC. Characterizing longitudinal change in accelerometry-based moderate-to-vigorous physical activity in the Hispanic Community Health Study/Study of Latinos and the Framingham Heart Study. BMC Public Health. 2023 Aug 24; 23(1):1614.View Related Profiles.

Spartano, Nicole
Xanthakis, Vanessa

PMID: 37620824; PMCID: PMC10464120; DOI: 10.1186/s12889-023-16442-9;

Wang X, Pathiravasan CH, Zhang Y, Trinquart L, Borrelli B, Spartano NL, Lin H, Nowak C, Kheterpal V, Benjamin EJ, McManus DD, Murabito JM, Liu C. Association of Depressive Symptom Trajectory With Physical Activity Collected by mHealth Devices in the Electronic Framingham Heart Study: Cohort Study. JMIR Ment Health. 2023 Jul 14; 10:e44529.View Related Profiles.

Borrelli, Belinda
Pathiravasan, Chathurangi
Liu, Chunyu
Benjamin, Emelia
Lin, Honghuang
Murabito, Joanne
Trinquart, Ludovic
Spartano, Nicole

PMID: 37450333; PMCID: PMC10382951; DOI: 10.2196/44529;

Showing 10 of 69 results. Show More

Perry AS, Dooley EE, Master H, Spartano NL, Brittain EL, Pettee Gabriel K. Physical Activity Over the Lifecourse and Cardiovascular Disease. Circ Res. 2023 Jun 09; 132(12):1725-1740. PMID: 37289900; PMCID: PMC10254078; DOI: 10.1161/CIRCRESAHA.123.322121;

Shapira-Daniels A, Kornej J, Spartano NL, Wang X, Zhang Y, Pathiravasan CH, Liu C, Trinquart L, Borrelli B, McManus DD, Murabito JM, Benjamin EJ, Lin H. Step Count, Self-reported Physical Activity, and Predicted 5-Year Risk of Atrial Fibrillation: Cross-sectional Analysis. J Med Internet Res. 2023 Mar 06; 25:e43123.View Related Profiles.

Shapira-Daniels, Ayelet
Borrelli, Belinda
Pathiravasan, Chathurangi
Liu, Chunyu
Benjamin, Emelia
Lin, Honghuang
Murabito, Joanne
Trinquart, Ludovic
Spartano, Nicole

PMID: 36877540; PMCID: PMC10028513; DOI: 10.2196/43123;

Trinquart L, Liu C, McManus DD, Nowak C, Lin H, Spartano NL, Borrelli B, Benjamin EJ, Murabito JM. Increasing Engagement in the Electronic Framingham Heart Study: Factorial Randomized Controlled Trial. J Med Internet Res. 2023 Jan 20; 25:e40784.View Related Profiles.

Borrelli, Belinda
Liu, Chunyu
Benjamin, Emelia
Lin, Honghuang
Murabito, Joanne
Trinquart, Ludovic
Spartano, Nicole

PMID: 36662544; PMCID: PMC9898831; DOI: 10.2196/40784;

Spartano NL, Wang R, Yang Q, Chernofsky A, Murabito JM, Levy D, Vasan RS, DeCarli C, Maillard P, Seshadri S, Beiser AS. Association of Physical Inactivity with MRI Markers of Brain Aging: Assessing Mediation by Cardiometabolic and Epigenetic Factors. J Alzheimers Dis. 2023; 95(2):561-572.View Related Profiles.

Beiser, Alexa
Murabito, Joanne
Spartano, Nicole
Yang, Qiong
Seshadri, Sudha

PMID: 37574733; PMCID: PMC11694349; DOI: 10.3233/JAD-230289;

Pathiravasan CH, Zhang Y, Wang X, Trinquart L, Benjamin EJ, Borrelli B, McManus DD, Kheterpal V, Lin H, Spartano NL, Schramm E, Liu C, Murabito JM. Factors associated with long-term use of digital devices in the electronic Framingham Heart Study. NPJ Digit Med. 2022 Dec 27; 5(1):195.View Related Profiles.

Borrelli, Belinda
Pathiravasan, Chathurangi
Liu, Chunyu
Benjamin, Emelia
Lin, Honghuang
Murabito, Joanne
Trinquart, Ludovic
Spartano, Nicole

PMID: 36572707; PMCID: PMC9792462; DOI: 10.1038/s41746-022-00735-1;

Paluch AE, Bajpai S, Ballin M, Bassett DR, Buford TW, Carnethon MR, Chernofsky A, Dooley EE, Ekelund U, Evenson KR, Galuska DA, Jefferis BJ, Kong L, Kraus WE, Larson MG, Lee IM, Matthews CE, Newton RL, Nordström A, Nordström P, Palta P, Patel AV, Pettee Gabriel K, Pieper CF, Pompeii L, Rees-Punia E, Spartano NL, Vasan RS, Whincup PH, Yang S, Fulton JE. Prospective Association of Daily Steps With Cardiovascular Disease: A Harmonized Meta-Analysis. Circulation. 2023 Jan 10; 147(2):122-131.View Related Profiles.

Larson, Martin
Spartano, Nicole

PMID: 36537288; PMCID: PMC9839547; DOI: 10.1161/CIRCULATIONAHA.122.061288;

Spartano NL, Wang R, Yang Q, Chernofsky A, Murabito JM, Vasan RS, Levy D, Beiser AS, Seshadri S. Association of Accelerometer-Measured Physical Activity and Sedentary Time with Epigenetic Markers of Aging. Med Sci Sports Exerc. 2023 Feb 01; 55(2):264-272.View Related Profiles.

Beiser, Alexa
Murabito, Joanne
Spartano, Nicole
Yang, Qiong
Seshadri, Sudha

PMID: 36107108; PMCID: PMC9840651; DOI: 10.1249/MSS.0000000000003041;

Walker ME, Spartano NL. Identifying Ultra-processed Foods in Nutrition Research: What a Proccess! Neurology. 2022 Jul 27.View Related Profiles.

Walker, Maura
Spartano, Nicole

PMID: 35896435

Walker ME, Spartano NL. Identifying Ultraprocessed Foods in Nutrition Research: What a Process! Neurology. 2022 Sep 06; 99(10):411-412.View Related Profiles.

Walker, Maura
Spartano, Nicole

PMID: 36219799

Almohamad M, Krall Kaye E, Mofleh D, Spartano NL. The association of sedentary behaviour and physical activity with periodontal disease in NHANES 2011-2012. J Clin Periodontol. 2022 Aug; 49(8):758-767. PMID: 35634657

Kaplan RC, Song RJ, Lin J, Xanthakis V, Hua S, Chernofsky A, Evenson KR, Walker ME, Cuthbertson C, Murabito JM, Cordero C, Daviglus M, Perreira KM, Gellman M, Sotres-Alvarez D, Vasan RS, Xue X, Spartano NL, Mossavar-Rahmani Y. Predictors of incident diabetes in two populations: framingham heart study and hispanic community health study / study of latinos. BMC Public Health. 2022 May 26; 22(1):1053.View Related Profiles.

Murabito, Joanne
Walker, Maura
Spartano, Nicole
Xanthakis, Vanessa

PMID: 35619100; PMCID: PMC9137165; DOI: 10.1186/s12889-022-13463-8;

Nayor M, Chernofsky A, Miller PE, Spartano NL, Murthy VL, Malhotra R, Houstis NE, Murabito JM, Clish CB, Larson MG, Vasan RS, Shah RV, Lewis GD. Integrative Analysis of Circulating Metabolite Levels That Correlate With Physical Activity and Cardiorespiratory Fitness. Circ Genom Precis Med. 2022 Jun; 15(3):e003592.View Related Profiles.

Murabito, Joanne
Larson, Martin
Nayor, Matthew
Spartano, Nicole

PMID: 35536222; PMCID: PMC9233103; DOI: 10.1161/CIRCGEN.121.003592;

Hammond MM, Zhang Y, Pathiravasan CH, Lin H, Sardana M, Trinquart L, Benjamin EJ, Borrelli B, Manders ES, Fusco K, Kornej J, Spartano NL, Kheterpal V, Nowak C, McManus DD, Liu C, Murabito JM. Relations Between BMI Trajectories and Habitual Physical Activity Measured by a Smartwatch in the Electronic Cohort of the Framingham Heart Study: Cohort Study. JMIR Cardio. 2022 Apr 27; 6(1):e32348.View Related Profiles.

Borrelli, Belinda
Pathiravasan, Chathurangi
Liu, Chunyu
Benjamin, Emelia
Lin, Honghuang
Murabito, Joanne
Trinquart, Ludovic
Spartano, Nicole

PMID: 35476038; PMCID: PMC9096636; DOI: 10.2196/32348;

Paluch AE, Bajpai S, Bassett DR, Carnethon MR, Ekelund U, Evenson KR, Galuska DA, Jefferis BJ, Kraus WE, Lee IM, Matthews CE, Omura JD, Patel AV, Pieper CF, Rees-Punia E, Dallmeier D, Klenk J, Whincup PH, Dooley EE, Pettee Gabriel K, Palta P, Pompeii LA, Chernofsky A, Larson MG, Vasan RS, Spartano N, Ballin M, Nordström P, Nordström A, Anderssen SA, Hansen BH, Cochrane JA, Dwyer T, Wang J, Ferrucci L, Liu F, Schrack J, Urbanek J, Saint-Maurice PF, Yamamoto N, Yoshitake Y, Newton RL, Yang S, Shiroma EJ, Fulton JE. Daily steps and all-cause mortality: a meta-analysis of 15 international cohorts. Lancet Public Health. 2022 03; 7(3):e219-e228.View Related Profiles.

Dallmeier Rojas, Dhayana
Larson, Martin
Spartano, Nicole

PMID: 35247352; PMCID: PMC9289978; DOI: 10.1016/S2468-2667(21)00302-9;

Zhang Y, Pathiravasan CH, Hammond MM, Liu H, Lin H, Sardana M, Trinquart L, Borrelli B, Manders ES, Kornej J, Spartano NL, Nowak C, Kheterpal V, Benjamin EJ, McManus DD, Murabito JM, Liu C. Comparison of Daily Routines Between Middle-aged and Older Participants With and Those Without Diabetes in the Electronic Framingham Heart Study: Cohort Study. JMIR Diabetes. 2022 Jan 07; 7(1):e29107.View Related Profiles.

Borrelli, Belinda
Pathiravasan, Chathurangi
Liu, Chunyu
Benjamin, Emelia
Lin, Honghuang
Murabito, Joanne
Trinquart, Ludovic
Spartano, Nicole

PMID: 34994694; PMCID: PMC8783285; DOI: 10.2196/29107;

Trethewey RE, Spartano NL, Vasan RS, Larson MG, O'Connor GT, Esliger DW, Petherick ES, Steiner MC. Body mass index across adulthood and the development of airflow obstruction and emphysema. Chron Respir Dis. 2022; 19:14799731221139294.View Related Profiles.

O'Connor, George
Larson, Martin
Spartano, Nicole

PMID: 36351077; PMCID: PMC9661572; DOI: 10.1177/14799731221139294;

Spartano NL, Himali JJ, Trinquart L, Yang Q, Weinstein G, Satizabal CL, Dukes KA, Beiser AS, Murabito JM, Vasan RS, Seshadri S. Accelerometer-Measured, Habitual Physical Activity and Circulating Brain-Derived Neurotrophic Factor: A Cross-Sectional Study. J Alzheimers Dis. 2022; 85(2):805-814.View Related Profiles.

Beiser, Alexa
Satizabal, Claudia
Weinstein, Galit
Himali, Jayandra
Murabito, Joanne
Dukes, Kimberly Ann
Trinquart, Ludovic
Spartano, Nicole
Yang, Qiong
Seshadri, Sudha

PMID: 34864673; DOI: 10.3233/JAD-215109;

Tarp J, Fagerland MW, Dalene KE, Johannessen JS, Hansen BH, Jefferis BJ, Whincup PH, Diaz KM, Hooker S, Howard VJ, Chernofsky A, Larson MG, Spartano NL, Vasan RS, Dohrn IM, Hagströmer M, Edwardson C, Yates T, Shiroma EJ, Dempsey PC, Wijndaele K, Anderssen SA, Lee IM, Ekelund U. Device-measured physical activity, adiposity and mortality: a harmonised meta-analysis of eight prospective cohort studies. Br J Sports Med. 2022 Jul; 56(13):725-732.View Related Profiles.

Larson, Martin
Spartano, Nicole

PMID: 34876405; PMCID: PMC9209690; DOI: 10.1136/bjsports-2021-104827;

Kornej J, Murabito JM, Zhang Y, Liu C, Trinquart L, Sardana M, Manders ES, Hammond MM, Spartano NL, Pathiravasan CH, Wang X, Borrelli B, McManus DD, Benjamin EJ, Lin H. No evidence of association between habitual physical activity and ECG traits: Insights from the electronic Framingham Heart Study. Cardiovasc Digit Health J. 2022 Feb; 3(1):56-58.View Related Profiles.

Borrelli, Belinda
Pathiravasan, Chathurangi
Liu, Chunyu
Benjamin, Emelia
Lin, Honghuang
Murabito, Joanne
Trinquart, Ludovic
Spartano, Nicole

PMID: 35265935; PMCID: PMC8890067; DOI: 10.1016/j.cvdhj.2021.11.004;

Nayor M, Chernofsky A, Spartano NL, Tanguay M, Blodgett JB, Murthy VL, Malhotra R, Houstis NE, Velagaleti RS, Murabito JM, Larson MG, Vasan RS, Shah RV, Lewis GD. Physical activity and fitness in the community: the Framingham Heart Study. Eur Heart J. 2021 11 21; 42(44):4565-4575.View Related Profiles.

Murabito, Joanne
Larson, Martin
Nayor, Matthew
Spartano, Nicole
Velagaleti, Raghava

PMID: 34436560; PMCID: PMC8633734; DOI: 10.1093/eurheartj/ehab580;

Spartano NL. What Are the Next Steps for Developing a National Steps Guideline? JAMA Netw Open. 2021 09 01; 4(9):e2125267. PMID: 34477855

Sardana M, Lin H, Zhang Y, Liu C, Trinquart L, Benjamin EJ, Manders ES, Fusco K, Kornej J, Hammond MM, Spartano N, Pathiravasan CH, Kheterpal V, Nowak C, Borrelli B, Murabito JM, McManus DD. Association of Habitual Physical Activity With Home Blood Pressure in the Electronic Framingham Heart Study (eFHS): Cross-sectional Study. J Med Internet Res. 2021 06 24; 23(6):e25591.View Related Profiles.

Borrelli, Belinda
Pathiravasan, Chathurangi
Liu, Chunyu
Benjamin, Emelia
Lin, Honghuang
Murabito, Joanne
Trinquart, Ludovic
Spartano, Nicole

PMID: 34185019; PMCID: PMC8277303; DOI: 10.2196/25591;

Barone Gibbs B, Hivert MF, Jerome GJ, Kraus WE, Rosenkranz SK, Schorr EN, Spartano NL, Lobelo F. Physical Activity as a Critical Component of First-Line Treatment for Elevated Blood Pressure or Cholesterol: Who, What, and How?: A Scientific Statement From the American Heart Association. Hypertension. 2021 08; 78(2):e26-e37. PMID: 34074137

Lee J, Walker ME, Bourdillon MT, Spartano NL, Rogers GT, Jacques PF, Vasan RS, Xanthakis V. Conjoint Associations of Adherence to Physical Activity and Dietary Guidelines With Cardiometabolic Health: The Framingham Heart Study. J Am Heart Assoc. 2021 04 06; 10(7):e019800.View Related Profiles.

Walker, Maura
Bourdillon , Max
Spartano, Nicole
Xanthakis, Vanessa

PMID: 33784828; PMCID: PMC8174320; DOI: 10.1161/JAHA.120.019800;

Pathiravasan CH, Zhang Y, Trinquart L, Benjamin EJ, Borrelli B, McManus DD, Kheterpal V, Lin H, Sardana M, Hammond MM, Spartano NL, Dunn AL, Schramm E, Nowak C, Manders ES, Liu H, Kornej J, Liu C, Murabito JM. Adherence of Mobile App-Based Surveys and Comparison With Traditional Surveys: eCohort Study. J Med Internet Res. 2021 01 20; 23(1):e24773.View Related Profiles.

Borrelli, Belinda
Pathiravasan, Chathurangi
Liu, Chunyu
Benjamin, Emelia
Lin, Honghuang
Murabito, Joanne
Trinquart, Ludovic
Spartano, Nicole

PMID: 33470944; PMCID: PMC7857942; DOI: 10.2196/24773;

Spartano NL, Pantoni L. What Can Longitudinal Observational Studies of Physical Activity Teach Us About Prevention of Dementia? Neurology. 2021 02 16; 96(7):297-298. PMID: 33408143

Ekelund U, Tarp J, Fagerland MW, Johannessen JS, Hansen BH, Jefferis BJ, Whincup PH, Diaz KM, Hooker S, Howard VJ, Chernofsky A, Larson MG, Spartano N, Vasan RS, Dohrn IM, Hagströmer M, Edwardson C, Yates T, Shiroma EJ, Dempsey P, Wijndaele K, Anderssen SA, Lee IM. Joint associations of accelero-meter measured physical activity and sedentary time with all-cause mortality: a harmonised meta-analysis in more than 44 000 middle-aged and older individuals. Br J Sports Med. 2020 Dec; 54(24):1499-1506.View Related Profiles.

Larson, Martin
Spartano, Nicole

PMID: 33239356; PMCID: PMC7719907; DOI: 10.1136/bjsports-2020-103270;

Chen GC, Qi Q, Hua S, Moon JY, Spartano NL, Vasan RS, Sotres-Alvarez D, Castaneda SF, Evenson KR, Perreira KM, Gallo LC, Pirzada A, Diaz KM, Daviglus ML, Gellman MD, Kaplan RC, Xue X, Mossavar-Rahmani Y. Accelerometer-assessed physical activity and incident diabetes in a population covering the adult life span: the Hispanic Community Health Study/Study of Latinos. Am J Clin Nutr. 2020 11 11; 112(5):1318-1327. PMID: 32910816; PMCID: PMC7657343; DOI: 10.1093/ajcn/nqaa232;

Lin H, Sardana M, Zhang Y, Liu C, Trinquart L, Benjamin EJ, Manders ES, Fusco K, Kornej J, Hammond MM, Spartano NL, Pathiravasan CH, Kheterpal V, Nowak C, Borrelli B, Murabito JM, McManus DD. Association of Habitual Physical Activity With Cardiovascular Disease Risk. Circ Res. 2020 10 23; 127(10):1253-1260.View Related Profiles.

Borrelli, Belinda
Pathiravasan, Chathurangi
Liu, Chunyu
Benjamin, Emelia
Lin, Honghuang
Murabito, Joanne
Trinquart, Ludovic
Spartano, Nicole

PMID: 32842915; PMCID: PMC7581630; DOI: 10.1161/CIRCRESAHA.120.317578;

Lin HP, Lynk N, Moore LL, Cabral HJ, Heffernan KS, Dumas AK, Hruska B, Zajdel RA, Gump BB, Spartano NL. A pragmatic approach to the comparison of wrist-based cutpoints of physical activity intensity for the MotionWatch8 accelerometer in children. PLoS One. 2020; 15(6):e0234725.View Related Profiles.

Cabral, Howard
Moore, Lynn
Spartano, Nicole

PMID: 32559207; PMCID: PMC7304605; DOI: 10.1371/journal.pone.0234725;

Lefferts WK, Augustine JA, Spartano NL, Hughes WE, Babcock MC, Heenan BK, Heffernan KS. Effects of Whey Protein Supplementation on Aortic Stiffness, Cerebral Blood Flow, and Cognitive Function in Community-Dwelling Older Adults: Findings from the ANCHORS A-WHEY Clinical Trial. Nutrients. 2020 Apr 10; 12(4). PMID: 32290271; PMCID: PMC7230701; DOI: 10.3390/nu12041054;

Virani SS, Alonso A, Benjamin EJ, Bittencourt MS, Callaway CW, Carson AP, Chamberlain AM, Chang AR, Cheng S, Delling FN, Djousse L, Elkind MSV, Ferguson JF, Fornage M, Khan SS, Kissela BM, Knutson KL, Kwan TW, Lackland DT, Lewis TT, Lichtman JH, Longenecker CT, Loop MS, Lutsey PL, Martin SS, Matsushita K, Moran AE, Mussolino ME, Perak AM, Rosamond WD, Roth GA, Sampson UKA, Satou GM, Schroeder EB, Shah SH, Shay CM, Spartano NL, Stokes A, Tirschwell DL, VanWagner LB, Tsao CW. Heart Disease and Stroke Statistics-2020 Update: A Report From the American Heart Association. Circulation. 2020 03 03; 141(9):e139-e596.View Related Profiles.

Stokes, Andrew
Benjamin, Emelia
Spartano, Nicole

PMID: 31992061

Spartano NL, Demissie S, Himali JJ, Dukes KA, Murabito JM, Vasan RS, Beiser AS, Seshadri S. Accelerometer-determined physical activity and cognitive function in middle-aged and older adults from two generations of the Framingham Heart Study. Alzheimers Dement (N Y). 2019; 5:618-626.View Related Profiles.

Beiser, Alexa
Himali, Jayandra
Murabito, Joanne
Dukes, Kimberly Ann
Spartano, Nicole
Demissie, Serkalem
Seshadri, Sudha

PMID: 31660424; PMCID: PMC6807299; DOI: 10.1016/j.trci.2019.08.007;

Spartano NL, Lin H, Sun F, Lunetta KL, Trinquart L, Valentino M, Manders ES, Pletcher MJ, Marcus GM, McManus DD, Benjamin EJ, Fox CS, Olgin JE, Murabito JM. Comparison of On-Site Versus Remote Mobile Device Support in the Framingham Heart Study Using the Health eHeart Study for Digital Follow-up: Randomized Pilot Study Set Within an Observational Study Design. JMIR Mhealth Uhealth. 2019 09 30; 7(9):e13238.View Related Profiles.

Benjamin, Emelia
Lin, Honghuang
Murabito, Joanne
Lunetta, Kathryn
Trinquart, Ludovic
Spartano, Nicole

PMID: 31573928; PMCID: PMC6792023; DOI: 10.2196/13238;

Ekelund U, Tarp J, Steene-Johannessen J, Hansen BH, Jefferis B, Fagerland MW, Whincup P, Diaz KM, Hooker SP, Chernofsky A, Larson MG, Spartano N, Vasan RS, Dohrn IM, Hagströmer M, Edwardson C, Yates T, Shiroma E, Anderssen SA, Lee IM. Dose-response associations between accelerometry measured physical activity and sedentary time and all cause mortality: systematic review and harmonised meta-analysis. BMJ. 2019 08 21; 366:l4570.View Related Profiles.

Larson, Martin
Spartano, Nicole

PMID: 31434697; PMCID: PMC6699591; DOI: 10.1136/bmj.l4570;

Spartano NL, Davis-Plourde KL, Himali JJ, Andersson C, Pase MP, Maillard P, DeCarli C, Murabito JM, Beiser AS, Vasan RS, Seshadri S. Association of Accelerometer-Measured Light-Intensity Physical Activity With Brain Volume: The Framingham Heart Study. JAMA Netw Open. 2019 04 05; 2(4):e192745.View Related Profiles.

Beiser, Alexa
Himali, Jayandra
Murabito, Joanne
Spartano, Nicole
Seshadri, Sudha

PMID: 31002329; PMCID: PMC6481600; DOI: 10.1001/jamanetworkopen.2019.2745;

Benjamin EJ, Muntner P, Alonso A, Bittencourt MS, Callaway CW, Carson AP, Chamberlain AM, Chang AR, Cheng S, Das SR, Delling FN, Djousse L, Elkind MSV, Ferguson JF, Fornage M, Jordan LC, Khan SS, Kissela BM, Knutson KL, Kwan TW, Lackland DT, Lewis TT, Lichtman JH, Longenecker CT, Loop MS, Lutsey PL, Martin SS, Matsushita K, Moran AE, Mussolino ME, O'Flaherty M, Pandey A, Perak AM, Rosamond WD, Roth GA, Sampson UKA, Satou GM, Schroeder EB, Shah SH, Spartano NL, Stokes A, Tirschwell DL, Tsao CW, Turakhia MP, VanWagner LB, Wilkins JT, Wong SS, Virani SS. Heart Disease and Stroke Statistics-2019 Update: A Report From the American Heart Association. Circulation. 2019 03 05; 139(10):e56-e528.View Related Profiles.

Stokes, Andrew
Benjamin, Emelia
Spartano, Nicole

PMID: 30700139

McManus DD, Trinquart L, Benjamin EJ, Manders ES, Fusco K, Jung LS, Spartano NL, Kheterpal V, Nowak C, Sardana M, Murabito JM. Design and Preliminary Findings From a New Electronic Cohort Embedded in the Framingham Heart Study. J Med Internet Res. 2019 03 01; 21(3):e12143.View Related Profiles.

Benjamin, Emelia
Murabito, Joanne
Trinquart, Ludovic
Spartano, Nicole

PMID: 30821691; PMCID: PMC6418484; DOI: 10.2196/12143;

Spartano NL, Lyass A, Larson MG, Tran T, Andersson C, Blease SJ, Esliger DW, Vasan RS, Murabito JM. Objective physical activity and physical performance in middle-aged and older adults. Exp Gerontol. 2019 05; 119:203-211.View Related Profiles.

Murabito, Joanne
Larson, Martin
Spartano, Nicole

PMID: 30771463; PMCID: PMC9728559; DOI: 10.1016/j.exger.2019.02.003;

Spartano NL, Davis-Plourde KL, Himali JJ, Murabito JM, Vasan RS, Beiser AS, Seshadri S. Self-Reported Physical Activity and Relations to Growth and Neurotrophic Factors in Diabetes Mellitus: The Framingham Offspring Study. J Diabetes Res. 2019; 2019:2718465.View Related Profiles.

Beiser, Alexa
Himali, Jayandra
Murabito, Joanne
Spartano, Nicole
Seshadri, Sudha

PMID: 30729134; PMCID: PMC6343169; DOI: 10.1155/2019/2718465;

Riffenburg KM, Spartano NL. Physical activity and weight maintenance: the utility of wearable devices and mobile health technology in research and clinical settings. Curr Opin Endocrinol Diabetes Obes. 2018 10; 25(5):310-314. PMID: 30063553

Spartano NL, Bernhardt J. Prestroke physical activity to reduce stroke severity: Moving to lower risk with light activity. Neurology. 2018 10 16; 91(16):727-728. PMID: 30232247

Spartano NL, Ngandu T. Fitness and dementia risk: Further evidence of the heart-brain connection. Neurology. 2018 04 10; 90(15):675-676. PMID: 29540586

Benjamin EJ, Virani SS, Callaway CW, Chamberlain AM, Chang AR, Cheng S, Chiuve SE, Cushman M, Delling FN, Deo R, de Ferranti SD, Ferguson JF, Fornage M, Gillespie C, Isasi CR, Jiménez MC, Jordan LC, Judd SE, Lackland D, Lichtman JH, Lisabeth L, Liu S, Longenecker CT, Lutsey PL, Mackey JS, Matchar DB, Matsushita K, Mussolino ME, Nasir K, O'Flaherty M, Palaniappan LP, Pandey A, Pandey DK, Reeves MJ, Ritchey MD, Rodriguez CJ, Roth GA, Rosamond WD, Sampson UKA, Satou GM, Shah SH, Spartano NL, Tirschwell DL, Tsao CW, Voeks JH, Willey JZ, Wilkins JT, Wu JH, Alger HM, Wong SS, Muntner P. Heart Disease and Stroke Statistics-2018 Update: A Report From the American Heart Association. Circulation. 2018 03 20; 137(12):e67-e492.View Related Profiles.

Benjamin, Emelia
Spartano, Nicole

PMID: 29386200

Heffernan KS, Augustine JA, Lefferts WK, Spartano NL, Hughes WE, Jorgensen RS, Gump BB. Arterial stiffness and cerebral hemodynamic pulsatility during cognitive engagement in younger and older adults. Exp Gerontol. 2018 01; 101:54-62. PMID: 29129735; DOI: 10.1016/j.exger.2017.11.004;

Tan ZS, Spartano NL, Beiser AS, DeCarli C, Auerbach SH, Vasan RS, Seshadri S. Physical Activity, Brain Volume, and Dementia Risk: The Framingham Study. J Gerontol A Biol Sci Med Sci. 2017 Jun 01; 72(6):789-795.View Related Profiles.

Beiser, Alexa
Spartano, Nicole
Auerbach, Sanford
Seshadri, Sudha
Ramachandran, Vasan

PMID: 27422439; PMCID: PMC6075525; DOI: 10.1093/gerona/glw130;

Spartano NL, Stevenson MD, Xanthakis V, Larson MG, Andersson C, Murabito JM, Vasan RS. Associations of objective physical activity with insulin sensitivity and circulating adipokine profile: the Framingham Heart Study. Clin Obes. 2017 Apr; 7(2):59-69.View Related Profiles.

Murabito, Joanne
Larson, Martin
Spartano, Nicole
Xanthakis, Vanessa
Ramachandran, Vasan

PMID: 28112860; PMCID: PMC5339058; DOI: 10.1111/cob.12177;

Lefferts WK, Augustine JA, Spartano NL, Atallah-Yunes NH, Heffernan KS, Gump BB. Racial differences in central hemodynamics and subclinical markers of cardiovascular disease risk in children. Journal of Pediatrics. 2017; 180:62-67.

Spartano NL, Heffernan KS, Dumas AK, Gump BB. Accelerometer-determined physical activity and the cardiovascular response to mental stress in children. J Sci Med Sport. 2017 Jan; 20(1):60-65. PMID: 27283342; PMCID: PMC5133178; DOI: 10.1016/j.jsams.2016.05.008;

Spartano NL, Lyass A, Larson MG, Lewis GD, Vasan RS. Submaximal Exercise Systolic Blood Pressure and Heart Rate at 20 Years of Follow-up: Correlates in the Framingham Heart Study. J Am Heart Assoc. 2016 May 27; 5(6).View Related Profiles.

Larson, Martin
Spartano, Nicole
Ramachandran, Vasan

PMID: 27233297; PMCID: PMC4937245; DOI: 10.1161/JAHA.115.002821;

Spartano NL, Himali JJ, Beiser AS, Lewis GD, DeCarli C, Vasan RS, Seshadri S. Midlife exercise blood pressure, heart rate, and fitness relate to brain volume 2 decades later. Neurology. 2016 Apr 5; 86(14):1313-9.View Related Profiles.

Beiser, Alexa
Himali, Jayandra
Spartano, Nicole
Seshadri, Sudha
Ramachandran, Vasan

PMID: 26865519; PMCID: PMC4826343; DOI: 10.1212/WNL.0000000000002415;

Andersson C, Lyass A, Larson MG, Spartano NL, Vita JA, Benjamin EJ, Murabito JM, Esliger DW, Blease SJ, Hamburg NM, Mitchell GF, Vasan RS. Physical activity measured by accelerometry and its associations with cardiac structure and vascular function in young and middle-aged adults. J Am Heart Assoc. 2015 Mar; 4(3):e001528.View Related Profiles.

Benjamin, Emelia
Murabito, Joanne
Vita, Joseph
Larson, Martin
Hamburg, Naomi
Spartano, Nicole
Ramachandran, Vasan

PMID: 25792127; PMCID: PMC4392434; DOI: 10.1161/JAHA.114.001528;

Heffernan KS, Spartano NL, Augustine JA, Lefferts WK, Hughes WE, Mitchell GF, Jorgensen RS, Gump BB. Carotid artery stiffness and hemodynamic pulsatility during cognitive engagement in healthy adults: a pilot investigation. Am J Hypertens. 2015 May; 28(5):615-22. PMID: 25384407; PMCID: PMC4462651; DOI: 10.1093/ajh/hpu198;

Hughes WE, Spartano NL, Augustine JA, Lefferts WK, Heffernan KS. Sex differences in noninvasive estimates of left ventricular pressure energetics but not myocardial oxygen demand in young adults. Artery Research. 2014; 197-204.

Spartano NL, Lamon-Fava S, Matthan NR, Ronxhi J, Greenberg AS, Obin MS, Lichtenstein AH. Regulation of ATP-binding cassette transporters and cholesterol efflux by glucose in primary human monocytes and murine bone marrow-derived macrophages. Exp Clin Endocrinol Diabetes. 2014 Sep; 122(8):463-8. PMID: 24838154; PMCID: PMC4279857; DOI: 10.1055/s-0034-1374600;

Spartano NL, Lamon-Fava S, Matthan NR, Obin MS, Greenberg AS, Lichtenstein AH. Linoleic acid suppresses cholesterol efflux and ATP-binding cassette transporters in murine bone marrow-derived macrophages. Lipids. 2014 May; 49(5):415-22. PMID: 24595513; PMCID: PMC4009986; DOI: 10.1007/s11745-014-3890-y;

Spartano NL, Augustine JA, Lefferts WK, Hughes WE, Redmond JG, Martin ED, Gump BB, Kuvin JT, Heffernan KS. Current Biomarker Findings. Arterial stiffness as a non-invasive tissue biomarker of cardiac target organ damage. Dove Medical Press. Auckland. 2014; 4:23-34.
Spartano NL, Augustine JA, Lefferts WK, Gump BB, Heffernan KS. Atherosclerosis. Carotid blood pressure reactivity to mental stress predicts carotid intima-media thickness. Elsevier. Amsterdam. 2014; 236(2):227-229.

Dillard A, Matthan NR, Spartano NL, Butkowski AE, Lichtenstein AH. Background diet and fat type alters plasma lipoprotein response but not aortic cholesterol accumulation in F1B Golden Syrian hamsters. Lipids. 2013 Dec; 48(12):1177-84. PMID: 24096944

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 69 publications over 12 distinct years, with a maximum of 13 publications in 2022

Bar chart showing 69 publications over 12 distinct years, with a maximum of 13 publications in 2022

Year	Publications
2013	1
2014	6
2015	1
2016	3
2017	4
2018	4
2019	8
2020	6
2021	9
2022	13
2023	6
2024	8

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2018 American Heart Association: Sandra A. Daugherty Award, Finalist

2017 American Heart Association Specialty Conferences : Best of American Heart Association Specialty Conferences

2016 American Heart Association: Early Investigator Travel Award

2015 American Heart Association Specialty Conferences: Best of American Heart Association Specialty Conferences

2015 Boston University Professional Development & Postdoctoral Affairs: Travel Award

2014-2016 NIH/NHLBI: Postdoctoral Training Grant award

2009-2012 NIH/NHLBI: Pre-doctoral Training Grant award

2007-2009 Tufts University: Friedman School of Nutrition Scholarship

2006 Syracuse University: Biology Award for Research Excellence

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