Keywords
Last Name

Lindsay Farrer, PhD

TitleProfessor
InstitutionBoston University School of Medicine
DepartmentMedicine
DivisionBiomedical Genetics
Address72 E. Concord St Instructional (L)
Boston MA 02118
Phone(617) 638-5393
ORCID ORCID Icon0000-0001-5533-4225
Other Positions
TitleSection Chief
InstitutionBoston University School of Medicine
DepartmentMedicine
DivisionBiomedical Genetics

TitleBoston University Distinguished Professor of Genetics
InstitutionBoston University School of Medicine
DepartmentMedicine
DivisionBiomedical Genetics

TitleProfessor
InstitutionBoston University School of Medicine
DepartmentOphthalmology

TitleProfessor
InstitutionBoston University School of Medicine
DepartmentNeurology

TitleProfessor
InstitutionBoston University School of Public Health
DepartmentBiostatistics

TitleProfessor
InstitutionBoston University School of Public Health
DepartmentEpidemiology

TitleGraduate Faculty (Primary Mentor of Grad Students)
InstitutionBoston University School of Medicine, Division of Graduate Medical Sciences

TitleMember
InstitutionBoston University
DepartmentBioinformatics Graduate Program

 Research Expertise & Professional Interests
Dr. Lindsay Farrer is a medical geneticist at Boston University Schools of Medicine and Public Health where he is Chief of Biomedical Genetics and a Professor of Medicine, Neurology, Ophthalmology, Genetics & Genomics, Epidemiology, and Biostatistics. Dr. Farrer is a graduate of the University of North Carolina in Chapel Hill, received his Ph.D. from the Indiana University School of Medicine, and gained additional training in genetic epidemiology at Yale University. He holds adjunct faculty positions at Harvard Medical School, Massachusetts General Hospital, and the Veterans Administration Medical Center in Bedford, Massachusetts. He is a Founding Fellow of the American College of Medical Genetics. Dr. Farrer teaches several courses in human genetics and genetic epidemiology at Boston University, directs Boston University’s Molecular Genetics Core Facility which offers DNA genotyping and sequencing services to investigators at the Boston Medical Center, and provides genetic counseling and testing to patients with a variety of inherited conditions.

Dr. Farrer’s research has lead to more than 300 publications on genetic risk factors for several familial neurodegenerative and other chronic diseases. In collaboration with other laboratories worldwide, his group has localized genes causing a variety of rare and common disorders including Alzheimer disease (AD), Wilson disease, Machado-Joseph disease, Waardenburg syndrome, hypertension, sensorineural deafness, and osteoarthritis. His group identified a functional genetic variant in the complement factor H gene which accounts for more than 30% of the attributable risk for age-related macular degeneration (AMD), the leading cause of progressive vision loss and blindness in the elderly. In collaboration with other researchers, Dr. Farrer is conducting genome wide association studies (GWAS) for several disorders including AD, substance dependence (cocaine, opiates, nicotine and alcohol), AMD and vasculitis. Dr. Farrer’s team is also developing methods for locating genes that influence the natural history of complex diseases and pharmacogenetic response.

Under Dr. Farrer’s leadership, the MIRAGE Project, a multi-center study of AD funded since 1991 by the National Institute on Aging, has made several important contributions to our understanding of the interactions between genetic and environmental factors for the disorder. This study has a particular emphasis on the genetics of AD in African Americans. Thus far, detailed family histories, risk factor data, and DNA specimens from more than 2,500 AD families have been collected as a part of this program. MIRAGE was the first study to demonstrate that genetic factors have a major role in the development of AD and that APOE e4 is more weakly associated with disease in men and persons older than 75 years. Dr. Farrer co-directed the international effort which demonstrated that SORL1 is genetically and functionally associated with AD, thus implicating intracellular protein trafficking as integral pathway in AD. His laboratory conducted genome wide association studies (GWAS) for AD in several populations including African Americans and an inbred Israeli-Arab community. Dr. Farrer serves on the Executive Committee of the national Alzheimer Disease Genetics Consortium and co-directs the data analysis effort for this large NIH-funded project. He and his colleagues recently discovered four new Alzheimer genes in the largest GWAS of AD to date.

 Self-Described Keywords
  • age-related macular degeneration
  • Alzheimer disease
  • gene mapping
  • genetic epidemiology
  • illicit drug dependence
 Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Desikan RS, Fan CC, Wang Y, Schork AJ, Cabral HJ, Cupples LA, Thompson WK, Besser L, Kukull WA, Holland D, Chen CH, Brewer JB, Karow DS, Kauppi K, Witoelar A, Karch CM, Bonham LW, Yokoyama JS, Rosen HJ, Miller BL, Dillon WP, Wilson DM, Hess CP, Pericak-Vance M, Haines JL, Farrer LA, Mayeux R, Hardy J, Goate AM, Hyman BT, Schellenberg GD, McEvoy LK, Andreassen OA, Dale AM. Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score. PLoS Med. 2017 Mar; 14(3):e1002258. PMID: 28323831.
    View in: PubMed
  2. Deming Y, Li Z, Kapoor M, Harari O, Del-Aguila JL, Black K, Carrell D, Cai Y, Fernandez MV, Budde J, Ma S, Saef B, Howells B, Huang KL, Bertelsen S, Fagan AM, Holtzman DM, Morris JC, Kim S, Saykin AJ, De Jager PL, Albert M, Moghekar A, O'Brien R, Riemenschneider M, Petersen RC, Blennow K, Zetterberg H, Minthon L, Van Deerlin VM, Lee VM, Shaw LM, Trojanowski JQ, Schellenberg G, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Peskind ER, Li G, Di Narzo AF. Genome-wide association study identifies four novel loci associated with Alzheimer's endophenotypes and disease modifiers. Acta Neuropathol. 2017 May; 133(5):839-856. PMID: 28247064.
    View in: PubMed
  3. Adkins AE, Hack LM, Bigdeli TB, Williamson VS, McMichael GO, Mamdani M, Edwards AC, Aliev F, Chan RF, Bhandari P, Raabe RC, Alaimo JT, Blackwell GG, Moscati A, Poland RS, Rood B, Patterson DG, Walsh D. Genomewide Association Study of Alcohol Dependence Identifies Risk Loci Altering Ethanol-Response Behaviors in Model Organisms. Alcohol Clin Exp Res. 2017 Feb 22. PMID: 28226201.
    View in: PubMed
  4. Jun GR, Chung J, Mez J, Barber R, Beecham GW, Bennett DA, Buxbaum JD, Byrd GS, Carrasquillo MM, Crane PK, Cruchaga C, De Jager P, Ertekin-Taner N, Evans D, Fallin MD, Foroud TM, Friedland RP, Goate AM, Graff-Radford NR, Hendrie H, Hall KS, Hamilton-Nelson KL, Inzelberg R, Kamboh MI, Kauwe JS, Kukull WA, Kunkle BW, Kuwano R, Larson EB, Logue MW, Manly JJ, Martin ER, Montine TJ, Mukherjee S, Naj A, Reiman EM, Reitz C, Sherva R, St George-Hyslop PH, Thornton T, Younkin SG, Vardarajan BN, Wang LS, Wendlund JR, Winslow AR. Transethnic genome-wide scan identifies novel Alzheimer's disease loci. Alzheimers Dement. 2017 Feb 07. PMID: 28183528.
    View in: PubMed
  5. Smith AH, Jensen KP, Li J, Nunez Y, Farrer LA, Hakonarson H, Cook-Sather SD, Kranzler HR, Gelernter J. Genome-wide association study of therapeutic opioid dosing identifies a novel locus upstream of OPRM1. Mol Psychiatry. 2017 Mar; 22(3):346-352. PMID: 28115739.
    View in: PubMed
  6. Haddick PC, Larson JL, Rathore N, Bhangale TR, Phung QT, Srinivasan K, Hansen DV, Lill JR. A Common Variant of IL-6R is Associated with Elevated IL-6 Pathway Activity in Alzheimer's Disease Brains. J Alzheimers Dis. 2017; 56(3):1037-1054. PMID: 28106546.
    View in: PubMed
  7. Wachman EM, Hayes MJ, Sherva R, Brown MS, Shrestha H, Logan BA, Heller NA, Nielsen DA, Farrer LA. Association of maternal and infant variants in PNOC and COMT genes with neonatal abstinence syndrome severity. Am J Addict. 2017 Jan; 26(1):42-49. PMID: 27983768.
    View in: PubMed
  8. Mez J, Chung J, Jun G, Kriegel J, Bourlas AP, Sherva R, Logue MW, Barnes LL, Bennett DA, Buxbaum JD, Byrd GS, Crane PK, Ertekin-Taner N, Evans D, Fallin MD, Foroud T, Goate A, Graff-Radford NR, Hall KS, Kamboh MI, Kukull WA, Larson EB, Manly JJ. Two novel loci, COBL and SLC10A2, for Alzheimer's disease in African Americans. Alzheimers Dement. 2017 Feb; 13(2):119-129. PMID: 27770636.
    View in: PubMed
  9. Wang Q, Polimanti R, Kranzler HR, Farrer LA, Zhao H, Gelernter J. Genetic factor common to schizophrenia and HIV infection is associated with risky sexual behavior: antagonistic vs. synergistic pleiotropic SNPs enriched for distinctly different biological functions. Hum Genet. 2017 Jan; 136(1):75-83. PMID: 27752767.
    View in: PubMed
  10. Vathipadiekal V, Farrell JJ, Wang S, Edward HL, Shappell H, Al-Rubaish AM, Al-Muhanna F, Naserullah Z, Alsuliman A, Qutub HO, Simkin I, Farrer LA, Jiang Z, Luo HY, Huang S, Mostoslavsky G, Murphy GJ, Patra PK, Chui DH, Alsultan A, Al-Ali AK, Sebastiani P, Steinberg MH. A candidate transacting modulator of fetal hemoglobin gene expression in the Arab-Indian haplotype of sickle cell anemia. Am J Hematol. 2016 Nov; 91(11):1118-1122. PMID: 27501013.
    View in: PubMed
  11. Polimanti R, Wang Q, Meda SA, Patel KT, Pearlson GD, Zhao H, Farrer LA, Kranzler HR, Gelernter J. The Interplay Between Risky Sexual Behaviors and Alcohol Dependence: Genome-Wide Association and Neuroimaging Support for LHPP as a Risk Gene. Neuropsychopharmacology. 2017 Feb; 42(3):598-605. PMID: 27531626.
    View in: PubMed
  12. Jaeger PA, Lucin KM, Britschgi M, Vardarajan B, Huang RP, Kirby ED, Abbey R, Boeve BF, Boxer AL, Farrer LA, Finch N, Graff-Radford NR, Head E, Hofree M, Huang R, Johns H, Karydas A, Knopman DS, Loboda A, Masliah E, Narasimhan R, Petersen RC, Podtelezhnikov A, Pradhan S, Rademakers R, Sun CH, Younkin SG, Miller BL, Ideker T, Wyss-Coray T. Erratum to: Network-driven plasma proteomics expose molecular changes in the Alzheimer's brain. Mol Neurodegener. 2016 May 23; 11(1):42. PMID: 27216421.
    View in: PubMed
  13. Cukier HN, Kunkle BW, Vardarajan BN, Rolati S, Hamilton-Nelson KL, Kohli MA, Whitehead PL, Dombroski BA, Van Booven D, Lang R, Dykxhoorn DM, Farrer LA, Cuccaro ML, Vance JM, Gilbert JR, Beecham GW, Martin ER, Carney RM, Mayeux R, Schellenberg GD, Byrd GS, Haines JL, Pericak-Vance MA. ABCA7 frameshift deletion associated with Alzheimer disease in African Americans. Neurol Genet. 2016 Jun; 2(3):e79. PMID: 27231719.
    View in: PubMed
  14. Chen J, Bacanu SA, Yu H, Zhao Z, Jia P, Kendler KS, Kranzler HR, Gelernter J, Farrer L, Minica C, Pool R, Milaneschi Y, Boomsma DI, Penninx BW, Tyndale RF, Ware JJ, Vink JM, Kaprio J, Munafò M, Chen X. Genetic Relationship between Schizophrenia and Nicotine Dependence. Sci Rep. 2016 May 10; 6:25671. PMID: 27164557.
    View in: PubMed
  15. Sherva R, Wang Q, Kranzler H, Zhao H, Koesterer R, Herman A, Farrer LA, Gelernter J. Genome-wide Association Study of Cannabis Dependence Severity, Novel Risk Variants, and Shared Genetic Risks. JAMA Psychiatry. 2016 May 01; 73(5):472-80. PMID: 27028160.
    View in: PubMed
  16. Vathipadiekal V, Alsultan A, Baltrusaitis K, Farrell JJ, Al-Rubaish AM, Al-Muhanna F, Naserullah Z, Suliman A, Patra PK, Milton JN, Farrer LA, Chui DH, Al-Ali AK, Sebastiani P, Steinberg MH. Homozygosity for a haplotype in the HBG2-OR51B4 region is exclusive to Arab-Indian haplotype sickle cell anemia. Am J Hematol. 2016 Jun; 91(6):E308-11. PMID: 27185208.
    View in: PubMed
  17. Jaeger PA, Lucin KM, Britschgi M, Vardarajan B, Huang RP, Kirby ED, Abbey R, Boeve BF, Boxer AL, Farrer LA, Finch N, Graff-Radford NR, Head E, Hoffree M, Huang R, Johns H, Karydas A, Knopman DS, Loboda A, Masliah E, Narasimhan R, Petersen RC, Podtelezhnikov A, Pradhan S, Rademakers R, Sun CH, Younkin SG, Miller BL, Ideker T, Wyss-Coray T. Network-driven plasma proteomics expose molecular changes in the Alzheimer's brain. Mol Neurodegener. 2016 Apr 26; 11:31. PMID: 27112350.
    View in: PubMed
  18. Jensen KP, Smith AH, Herman AI, Farrer LA, Kranzler HR, Sofuoglu M, Gelernter J. A protocadherin gene cluster regulatory variant is associated with nicotine withdrawal and the urge to smoke. Mol Psychiatry. 2017 Feb; 22(2):242-249. PMID: 27067016.
    View in: PubMed
  19. Fan Q, Verhoeven VJ, Wojciechowski R, Barathi VA, Hysi PG, Guggenheim JA, Höhn R, Vitart V, Khawaja AP, Yamashiro K, Hosseini SM, Lehtimäki T, Lu Y, Haller T, Xie J, Delcourt C, Pirastu M, Wedenoja J, Gharahkhani P, Venturini C, Miyake M, Hewitt AW, Guo X, Mazur J, Huffman JE, Williams KM, Polasek O, Campbell H, Rudan I, Vatavuk Z, Wilson JF, Joshi PK, McMahon G, St Pourcain B, Evans DM, Simpson CL, Schwantes-An TH, Igo RP, Mirshahi A, Cougnard-Gregoire A, Bellenguez C, Blettner M, Raitakari O, Kähönen M, Seppala I, Zeller T, Meitinger T. Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error. Nat Commun. 2016; 7:11008. PMID: 27020472.
    View in: PubMed
  20. Ridge PG, Hoyt KB, Boehme K, Mukherjee S, Crane PK, Haines JL, Mayeux R, Farrer LA, Pericak-Vance MA, Schellenberg GD, Kauwe JS. Assessment of the genetic variance of late-onset Alzheimer's disease. Neurobiol Aging. 2016 May; 41:200.e13-20. PMID: 27036079.
    View in: PubMed
  21. Kohli MA, Cukier HN, Hamilton-Nelson KL, Rolati S, Kunkle BW, Whitehead PL, Züchner SL, Farrer LA, Martin ER, Beecham GW, Haines JL, Vance JM, Cuccaro ML, Gilbert JR, Schellenberg GD, Carney RM, Pericak-Vance MA. Segregation of a rare TTC3 variant in an extended family with late-onset Alzheimer disease. Neurol Genet. 2016 Feb; 2(1):e41. PMID: 27066578.
    View in: PubMed
  22. Fritsche LG, Igl W, Bailey JN, Grassmann F, Sengupta S, Bragg-Gresham JL, Burdon KP, Hebbring SJ, Wen C, Gorski M, Kim IK, Cho D, Zack D, Souied E, Scholl HP, Bala E, Lee KE, Hunter DJ, Sardell RJ, Mitchell P, Merriam JE, Cipriani V, Hoffman JD, Schick T, Lechanteur YT, Guymer RH, Johnson MP, Jiang Y, Stanton CM, Buitendijk GH, Zhan X, Kwong AM, Boleda A, Brooks M, Gieser L, Ratnapriya R, Branham KE, Foerster JR, Heckenlively JR, Othman MI, Vote BJ, Liang HH, Souzeau E, McAllister IL, Isaacs T, Hall J, Lake S, Mackey DA, Constable IJ, Craig JE, Kitchner TE, Yang Z, Su Z, Luo H, Chen D, Ouyang H, Flagg K, Lin D, Mao G, Ferreyra H, Stark K, von Strachwitz CN, Wolf A, Brandl C, Rudolph G, Olden M, Morrison MA, Morgan DJ, Schu M, Ahn J, Silvestri G, Tsironi EE, Park KH, Farrer LA, Orlin A, Brucker A, Li M, Curcio CA, Mohand-Saïd S, Sahel JA, Audo I, Benchaboune M, Cree AJ, Rennie CA, Goverdhan SV, Grunin M, Hagbi-Levi S, Campochiaro P, Katsanis N, Holz FG, Blond F, Blanché H, Deleuze JF, Igo RP, Truitt B, Peachey NS, Meuer SM, Myers CE, Moore EL, Klein R, Hauser MA, Postel EA, Courtenay MD, Schwartz SG, Kovach JL, Scott WK, Liew G, Tan AG, Gopinath B, Merriam JC, Smith RT, Khan JC, Shahid H, Moore AT, McGrath JA, Laux R, Brantley MA, Agarwal A, Ersoy L, Caramoy A, Langmann T, Saksens NT, de Jong EK, Hoyng CB, Cain MS, Richardson AJ, Martin TM, Blangero J, Weeks DE, Dhillon B, van Duijn CM, Doheny KF, Romm J, Klaver CC, Hayward C, Gorin MB, Klein ML, Baird PN, den Hollander AI, Fauser S, Yates JR, Allikmets R, Wang JJ, Schaumberg DA, Klein BE, Hagstrom SA, Chowers I, Lotery AJ, Léveillard T, Zhang K, Brilliant MH, Hewitt AW, Swaroop A, Chew EY, Pericak-Vance MA, DeAngelis M, Stambolian D, Haines JL, Iyengar SK, Weber BH, Abecasis GR, Heid IM. A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants. Nat Genet. 2016 Feb; 48(2):134-43. PMID: 26691988.
    View in: PubMed
  23. Hohman TJ, Bush WS, Jiang L, Brown-Gentry KD, Torstenson ES, Dudek SM, Mukherjee S, Naj A, Kunkle BW, Ritchie MD, Martin ER, Schellenberg GD, Mayeux R, Farrer LA, Pericak-Vance MA, Haines JL, Thornton-Wells TA. Discovery of gene-gene interactions across multiple independent data sets of late onset Alzheimer disease from the Alzheimer Disease Genetics Consortium. Neurobiol Aging. 2016 Feb; 38:141-50. PMID: 26827652.
    View in: PubMed
  24. Ghani M, Reitz C, Cheng R, Vardarajan BN, Jun G, Sato C, Naj A, Rajbhandary R, Wang LS, Valladares O, Lin CF, Larson EB, Graff-Radford NR, Evans D, De Jager PL, Crane PK, Buxbaum JD, Murrell JR, Raj T, Ertekin-Taner N, Logue M, Baldwin CT, Green RC, Barnes LL, Cantwell LB, Fallin MD, Go RC, Griffith PA, Obisesan TO, Manly JJ, Lunetta KL, Kamboh MI, Lopez OL, Bennett DA, Hendrie H, Hall KS, Goate AM, Byrd GS, Kukull WA, Foroud TM, Haines JL, Farrer LA, Pericak-Vance MA, Lee JH, Schellenberg GD, St George-Hyslop P, Mayeux R, Rogaeva E. Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals. JAMA Neurol. 2015 Nov; 72(11):1313-23. PMID: 26366463.
    View in: PubMed
  25. Polimanti R, Zhang H, Smith AH, Zhao H, Farrer LA, Kranzler HR, Gelernter J. Genome-wide association study of body mass index in subjects with alcohol dependence. Addict Biol. 2017 Mar; 22(2):535-549. PMID: 26458734.
    View in: PubMed
  26. Hancock DB, Reginsson GW, Gaddis NC, Chen X, Saccone NL, Lutz SM, Qaiser B, Sherva R, Steinberg S, Zink F, Stacey SN, Glasheen C, Chen J, Gu F, Frederiksen BN, Loukola A, Gudbjartsson DF, Brüske I, Landi MT, Bickeböller H, Madden P, Farrer L, Kaprio J, Kranzler HR, Gelernter J, Baker TB, Kraft P, Amos CI, Caporaso NE, Hokanson JE, Bierut LJ, Thorgeirsson TE, Johnson EO, Stefansson K. Genome-wide meta-analysis reveals common splice site acceptor variant in CHRNA4 associated with nicotine dependence. Transl Psychiatry. 2015; 5:e651. PMID: 26440539.
    View in: PubMed
  27. Barral S, Cheng R, Reitz C, Vardarajan B, Lee J, Kunkle B, Beecham G, Cantwell LS, Pericak-Vance MA, Farrer LA, Haines JL, Goate AM, Foroud T, Boerwinkle E, Schellenberg GD, Mayeux R. Linkage analyses in Caribbean Hispanic families identify novel loci associated with familial late-onset Alzheimer's disease. Alzheimers Dement. 2015 Dec; 11(12):1397-406. PMID: 26433351.
    View in: PubMed
  28. Nho K, Farrer LA, Saykin AJ. Reply: To PMID 25559091. Ann Neurol. 2015 Nov; 78(5):836-7. PMID: 26284454.
    View in: PubMed
  29. Kunkle BW, Jaworski J, Barral S, Vardarajan B, Beecham GW, Martin ER, Cantwell LS, Partch A, Bird TD, Raskind WH, DeStefano AL, Carney RM, Cuccaro M, Vance JM, Farrer LA, Goate AM, Foroud T, Mayeux RP, Schellenberg GD, Haines JL, Pericak-Vance MA. Genome-wide linkage analyses of non-Hispanic white families identify novel loci for familial late-onset Alzheimer's disease. Alzheimers Dement. 2016 Jan; 12(1):2-10. PMID: 26365416.
    View in: PubMed
  30. Sulovari A, Kranzler HR, Farrer LA, Gelernter J, Li D. Further analyses support the association between light eye color and alcohol dependence. Am J Med Genet B Neuropsychiatr Genet. 2015 Dec; 168(8):757-60. PMID: 26290254.
    View in: PubMed
  31. Nelson EC, Agrawal A, Heath AC, Bogdan R, Sherva R, Zhang B, Al-Hasani R, Bruchas MR, Chou YL, Demers CH, Carey CE, Conley ED, Fakira AK, Farrer LA, Goate A, Gordon S, Henders AK, Hesselbrock V, Kapoor M, Lynskey MT, Madden PA, Moron JA, Rice JP, Saccone NL, Schwab SG, Shand FL, Todorov AA, Wallace L, Wang T, Wray NR, Zhou X, Degenhardt L, Martin NG, Hariri AR, Kranzler HR, Gelernter J, Bierut LJ, Clark DJ, Montgomery GW. Evidence of CNIH3 involvement in opioid dependence. Mol Psychiatry. 2016 May; 21(5):608-14. PMID: 26239289.
    View in: PubMed
  32. Morrison MA, Magalhaes TR, Ramke J, Smith SE, Ennis S, Simpson CL, Portas L, Murgia F, Ahn J, Dardenne C, Mayne K, Robinson R, Morgan DJ, Brian G, Lee L, Woo SJ, Zacharaki F, Tsironi EE, Miller JW, Kim IK, Park KH, Bailey-Wilson JE, Farrer LA, Stambolian D, DeAngelis MM. Ancestry of the Timorese: age-related macular degeneration associated genotype and allele sharing among human populations from throughout the world. Front Genet. 2015; 6:238. PMID: 26217379.
    View in: PubMed
  33. Wachman EM, Hayes MJ, Sherva R, Brown MS, Davis JM, Farrer LA, Nielsen DA. Variations in opioid receptor genes in neonatal abstinence syndrome. Drug Alcohol Depend. 2015 Oct 1; 155:253-9. PMID: 26233486.
    View in: PubMed
  34. Farrer LA. Expanding the genomic roadmap of Alzheimer's disease. Lancet Neurol. 2015 Aug; 14(8):783-5. PMID: 26141618.
    View in: PubMed
  35. Tosto G, Fu H, Vardarajan BN, Lee JH, Cheng R, Reyes-Dumeyer D, Lantigua R, Medrano M, Jimenez-Velazquez IZ, Elkind MS, Wright CB, Sacco RL, Pericak-Vance M, Farrer L, Rogaeva E, St George-Hyslop P, Reitz C, Mayeux R. F-box/LRR-repeat protein 7 is genetically associated with Alzheimer's disease. Ann Clin Transl Neurol. 2015 Aug; 2(8):810-20. PMID: 26339675.
    View in: PubMed
  36. Hohman TJ, Cooke-Bailey JN, Reitz C, Jun G, Naj A, Beecham GW, Liu Z, Carney RM, Vance JM, Cuccaro ML, Rajbhandary R, Vardarajan BN, Wang LS, Valladares O, Lin CF, Larson EB, Graff-Radford NR, Evans D, De Jager PL, Crane PK, Buxbaum JD, Murrell JR, Raj T, Ertekin-Taner N, Logue MW, Baldwin CT, Green RC, Barnes LL, Cantwell LB, Fallin MD, Go RC, Griffith P, Obisesan TO, Manly JJ, Lunetta KL, Kamboh MI, Lopez OL, Bennett DA, Hardy J, Hendrie HC, Hall KS, Goate AM, Lang R, Byrd GS, Kukull WA, Foroud TM, Farrer LA, Martin ER, Pericak-Vance MA, Schellenberg GD, Mayeux R, Haines JL, Thornton-Wells TA. Global and local ancestry in African-Americans: Implications for Alzheimer's disease risk. Alzheimers Dement. 2016 Mar; 12(3):233-43. PMID: 26092349.
    View in: PubMed
  37. Xu K, Kranzler HR, Sherva R, Sartor CE, Almasy L, Koesterer R, Zhao H, Farrer LA, Gelernter J. Genomewide Association Study for Maximum Number of Alcoholic Drinks in European Americans and African Americans. Alcohol Clin Exp Res. 2015 Jul; 39(7):1137-47. PMID: 26036284.
    View in: PubMed
  38. Zhdanova IV, Rogers J, González-Martínez J, Farrer LA. The ticking clock of Cayo Santiago macaques and its implications for understanding human circadian rhythm disorders. Am J Primatol. 2016 Jan; 78(1):117-26. PMID: 25940511.
    View in: PubMed
  39. Sulovari A, Kranzler HR, Farrer LA, Gelernter J, Li D. Eye color: A potential indicator of alcohol dependence risk in European Americans. Am J Med Genet B Neuropsychiatr Genet. 2015 Jul; 168B(5):347-53. PMID: 25921801.
    View in: PubMed
  40. Desikan RS, Schork AJ, Wang Y, Thompson WK, Dehghan A, Ridker PM, Chasman DI, McEvoy LK, Holland D, Chen CH, Karow DS, Brewer JB, Hess CP, Williams J, Sims R, O'Donovan MC, Choi SH, Bis JC, Ikram MA, Gudnason V, DeStefano AL, van der Lee SJ, Psaty BM, van Duijn CM, Launer L, Seshadri S, Pericak-Vance MA, Mayeux R, Haines JL, Farrer LA, Hardy J, Ulstein ID, Aarsland D, Fladby T, White LR, Sando SB, Rongve A, Witoelar A, Djurovic S, Hyman BT, Snaedal J, Steinberg S, Stefansson H, Stefansson K, Schellenberg GD, Andreassen OA, Dale AM. Polygenic Overlap Between C-Reactive Protein, Plasma Lipids, and Alzheimer Disease. Circulation. 2015 Jun 9; 131(23):2061-9. PMID: 25862742.
    View in: PubMed
  41. Clarke TK, Smith AH, Gelernter J, Kranzler HR, Farrer LA, Hall LS, Fernandez-Pujals AM, MacIntyre DJ, Smith BH, Hocking LJ, Padmanabhan S, Hayward C, Thomson PA, Porteous DJ, Deary IJ, McIntosh AM. Polygenic risk for alcohol dependence associates with alcohol consumption, cognitive function and social deprivation in a population-based cohort. Addict Biol. 2016 Mar; 21(2):469-80. PMID: 25865819.
    View in: PubMed
  42. Hart AB, Lynch KG, Farrer L, Gelernter J, Kranzler HR. Which alcohol use disorder criteria contribute to the association of ADH1B with alcohol dependence? Addict Biol. 2016 Jul; 21(4):924-38. PMID: 25828809.
    View in: PubMed
  43. Jun G, Ibrahim-Verbaas CA, Vronskaya M, Lambert JC, Chung J, Naj AC, Kunkle BW, Wang LS, Bis JC, Bellenguez C, Harold D, Lunetta KL, Destefano AL, Grenier-Boley B, Sims R, Beecham GW, Smith AV, Chouraki V, Hamilton-Nelson KL, Ikram MA, Fievet N, Denning N, Martin ER, Schmidt H, Kamatani Y, Dunstan ML, Valladares O, Laza AR, Zelenika D, Ramirez A, Foroud TM, Choi SH, Boland A, Becker T, Kukull WA, van der Lee SJ, Pasquier F, Cruchaga C, Beekly D, Fitzpatrick AL, Hanon O, Gill M, Barber R, Gudnason V, Campion D, Love S, Bennett DA, Amin N, Berr C, Tsolaki M, Buxbaum JD, Lopez OL, Deramecourt V, Fox NC, Cantwell LB, Tárraga L, Dufouil C, Hardy J, Crane PK, Eiriksdottir G, Hannequin D, Clarke R, Evans D, Mosley TH, Letenneur L, Brayne C, Maier W, De Jager P, Emilsson V, Dartigues JF, Hampel H, Kamboh MI, de Bruijn RF, Tzourio C, Pastor P, Larson EB, Rotter JI, O'Donovan MC, Montine TJ, Nalls MA, Mead S, Reiman EM, Jonsson PV, Holmes C, St George-Hyslop PH, Boada M, Passmore P, Wendland JR, Schmidt R, Morgan K, Winslow AR, Powell JF, Carasquillo M, Younkin SG, Jakobsdóttir J, Kauwe JS, Wilhelmsen KC, Rujescu D, Nöthen MM, Hofman A, Jones L. A novel Alzheimer disease locus located near the gene encoding tau protein. Mol Psychiatry. 2016 Jan; 21(1):108-17. PMID: 25778476.
    View in: PubMed
  44. Desikan RS, Schork AJ, Wang Y, Witoelar A, Sharma M, McEvoy LK, Holland D, Brewer JB, Chen CH, Thompson WK, Harold D, Williams J, Owen MJ, O'Donovan MC, Pericak-Vance MA, Mayeux R, Haines JL, Farrer LA, Schellenberg GD, Heutink P, Singleton AB, Brice A, Wood NW, Hardy J, Martinez M, Choi SH, DeStefano A, Ikram MA, Bis JC, Smith A, Fitzpatrick AL, Launer L, van Duijn C, Seshadri S, Ulstein ID, Aarsland D, Fladby T, Djurovic S, Hyman BT, Snaedal J, Stefansson H, Stefansson K, Gasser T, Andreassen OA, Dale AM. Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus. Mol Psychiatry. 2015 Dec; 20(12):1588-95. PMID: 25687773.
    View in: PubMed
  45. Nho K, Kim S, Risacher SL, Shen L, Corneveaux JJ, Swaminathan S, Lin H, Ramanan VK, Liu Y, Foroud TM, Inlow MH, Siniard AL, Reiman RA, Aisen PS, Petersen RC, Green RC, Jack CR, Weiner MW, Baldwin CT, Lunetta KL, Farrer LA. Protective variant for hippocampal atrophy identified by whole exome sequencing. Ann Neurol. 2015 Mar; 77(3):547-52. PMID: 25559091.
    View in: PubMed
  46. Wang LS, Naj AC, Graham RR, Crane PK, Kunkle BW, Cruchaga C, Murcia JD, Cannon-Albright L, Baldwin CT, Zetterberg H, Blennow K, Kukull WA, Faber KM, Schupf N, Norton MC, Tschanz JT, Munger RG, Corcoran CD, Rogaeva E. Rarity of the Alzheimer disease-protective APP A673T variant in the United States. JAMA Neurol. 2015 Feb; 72(2):209-16. PMID: 25531812.
    View in: PubMed
  47. Sebastiani P, Farrell JJ, Alsultan A, Wang S, Edward HL, Shappell H, Bae H, Milton JN, Baldwin CT, Al-Rubaish AM, Naserullah Z, Al-Muhanna F, Alsuliman A, Patra PK, Farrer LA, Ngo D, Vathipadiekal V, Chui DH, Al-Ali AK, Steinberg MH. BCL11A enhancer haplotypes and fetal hemoglobin in sickle cell anemia. Blood Cells Mol Dis. 2015 Mar; 54(3):224-30. PMID: 25703683.
    View in: PubMed
  48. Inzelberg R, Massarwa M, Schechtman E, Strugatsky R, Farrer LA, Friedland RP. Estimating the risk for conversion from mild cognitive impairment to Alzheimer's disease in an elderly Arab community. J Alzheimers Dis. 2015; 45(3):865-71. PMID: 25624416.
    View in: PubMed
  49. Wetzel-Smith MK, Hunkapiller J, Bhangale TR, Srinivasan K, Maloney JA, Atwal JK, Sa SM, Yaylaoglu MB, Foreman O, Ortmann W, Rathore N, Hansen DV, Tessier-Lavigne M. A rare mutation in UNC5C predisposes to late-onset Alzheimer's disease and increases neuronal cell death. Nat Med. 2014 Dec; 20(12):1452-7. PMID: 25419706.
    View in: PubMed
  50. Naj AC, Jun G, Reitz C, Kunkle BW, Perry W, Park YS, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang LS, Kauwe JS, Huentelman MJ, Myers AJ, Bird TD, Boeve BF, Baldwin CT, Jarvik GP, Crane PK, Rogaeva E, Barmada MM, Demirci FY, Cruchaga C, Kramer PL, Ertekin-Taner N, Hardy J, Graff-Radford NR, Green RC, Larson EB, St George-Hyslop PH, Buxbaum JD, Evans DA, Schneider JA, Lunetta KL, Kamboh MI, Saykin AJ, Reiman EM, De Jager PL, Bennett DA, Morris JC, Montine TJ, Goate AM, Blacker D, Tsuang DW, Hakonarson H, Kukull WA, Foroud TM, Martin ER, Haines JL, Mayeux RP, Farrer LA, Schellenberg GD, Pericak-Vance MA. Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study. JAMA Neurol. 2014 Nov; 71(11):1394-404. PMID: 25199842.
    View in: PubMed
  51. Levey DF, Le-Niculescu H, Frank J, Ayalew M, Jain N, Kirlin B, Learman R, Winiger E, Rodd Z, Shekhar A, Schork N, Kiefe F, Wodarz N, Müller-Myhsok B, Dahmen N. Genetic risk prediction and neurobiological understanding of alcoholism. Transl Psychiatry. 2014; 4:e456. PMID: 25268260.
    View in: PubMed
  52. Li D, Zhao H, Kranzler HR, Li MD, Jensen KP, Zayats T, Farrer LA, Gelernter J. Genome-wide association study of copy number variations (CNVs) with opioid dependence. Neuropsychopharmacology. 2015 Mar; 40(4):1016-26. PMID: 25345593.
    View in: PubMed
  53. Richardson TG, Minica C, Heron J, Tavare J, MacKenzie A, Day I, Lewis G, Hickman M, Vink JM, Gelernter J, Kranzler HR, Farrer LA, Munafò M, Wynick D. Evaluating the role of a galanin enhancer genotype on a range of metabolic, depressive and addictive phenotypes. Am J Med Genet B Neuropsychiatr Genet. 2014 Dec; 165B(8):654-64. PMID: 25228436.
    View in: PubMed
  54. Gelernter J, Kranzler HR, Sherva R, Almasy L, Herman AI, Koesterer R, Zhao H, Farrer LA. Genome-wide association study of nicotine dependence in American populations: identification of novel risk loci in both African-Americans and European-Americans. Biol Psychiatry. 2015 Mar 1; 77(5):493-503. PMID: 25555482.
    View in: PubMed
  55. Beecham GW, Hamilton K, Naj AC, Martin ER, Huentelman M, Myers AJ, Corneveaux JJ, Hardy J, Vonsattel JP, Younkin SG, Bennett DA, De Jager PL, Larson EB, Crane PK, Kamboh MI, Kofler JK, Mash DC, Duque L, Gilbert JR, Gwirtsman H, Buxbaum JD, Kramer P, Dickson DW, Farrer LA, Frosch MP, Ghetti B, Haines JL, Hyman BT, Kukull WA, Mayeux RP, Pericak-Vance MA, Schneider JA, Trojanowski JQ, Reiman EM. Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias. PLoS Genet. 2014 Sep; 10(9):e1004606. PMID: 25188341.
    View in: PubMed
  56. Repunte-Canonigo V, Herman MA, Kawamura T, Kranzler HR, Sherva R, Gelernter J, Farrer LA, Roberto M, Sanna PP. Nf1 regulates alcohol dependence-associated excessive drinking and gamma-aminobutyric acid release in the central amygdala in mice and is associated with alcohol dependence in humans. Biol Psychiatry. 2015 May 15; 77(10):870-9. PMID: 25483400.
    View in: PubMed
  57. Jun G, Asai H, Zeldich E, Drapeau E, Chen C, Chung J, Park JH, Kim S, Haroutunian V, Foroud T, Kuwano R, Haines JL, Pericak-Vance MA, Schellenberg GD, Lunetta KL, Kim JW, Buxbaum JD, Mayeux R, Ikezu T, Abraham CR, Farrer LA. PLXNA4 is associated with Alzheimer disease and modulates tau phosphorylation. Ann Neurol. 2014 Sep; 76(3):379-92. PMID: 25043464.
    View in: PubMed
  58. Allen M, Kachadoorian M, Quicksall Z, Zou F, Chai HS, Younkin C, Crook JE, Pankratz VS, Carrasquillo MM, Krishnan S, Nguyen T, Ma L, Malphrus K, Lincoln S, Bisceglio G, Kolbert CP, Jen J, Mukherjee S, Kauwe JK, Crane PK, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD, Parisi JE, Petersen RC, Graff-Radford NR, Dickson DW, Younkin SG, Ertekin-Taner N. Association of MAPT haplotypes with Alzheimer's disease risk and MAPT brain gene expression levels. Alzheimers Res Ther. 2014; 6(4):39. PMID: 25324900.
    View in: PubMed
  59. Escott-Price V, Bellenguez C, Wang LS, Choi SH, Harold D, Jones L, Holmans P, Gerrish A, Vedernikov A, Richards A, DeStefano AL, Lambert JC, Ibrahim-Verbaas CA, Naj AC, Sims R, Jun G, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thornton-Wells TA, Denning N, Smith AV, Chouraki V, Thomas C, Ikram MA, Zelenika D, Vardarajan BN, Kamatani Y, Lin CF, Schmidt H, Kunkle B, Dunstan ML, Vronskaya M. Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease. PLoS One. 2014; 9(6):e94661. PMID: 24922517.
    View in: PubMed
  60. Ratnapriya R, Zhan X, Fariss RN, Branham KE, Zipprer D, Chakarova CF, Sergeev YV, Campos MM, Othman M, Friedman JS, Maminishkis A, Waseem NH, Brooks M, Rajasimha HK, Edwards AO, Lotery A, Klein BE, Truitt BJ, Li B, Schaumberg DA, Morgan DJ, Morrison MA, Souied E, Tsironi EE, Grassmann F, Fishman GA, Silvestri G, Scholl HP, Kim IK, Ramke J, Tuo J, Merriam JE, Merriam JC, Park KH, Olson LM, Farrer LA, Johnson MP, Peachey NS, Lathrop M, Baron RV, Igo RP, Klein R, Hagstrom SA, Kamatani Y, Martin TM, Jiang Y, Conley Y, Sahel JA, Zack DJ, Chan CC, Pericak-Vance MA, Jacobson SG, Gorin MB, Klein ML, Allikmets R, Iyengar SK, Weber BH, Haines JL, Léveillard T, Deangelis MM, Stambolian D, Weeks DE, Bhattacharya SS, Chew EY, Heckenlively JR, Abecasis GR, Swaroop A. Rare and common variants in extracellular matrix gene Fibrillin 2 (FBN2) are associated with macular degeneration. Hum Mol Genet. 2014 Nov 1; 23(21):5827-37. PMID: 24899048.
    View in: PubMed
  61. Shen L, Thompson PM, Potkin SG, Bertram L, Farrer LA, Foroud TM, Green RC, Hu X, Huentelman MJ, Kim S, Kauwe JS, Li Q, Liu E, Macciardi F, Moore JH, Munsie L, Nho K, Ramanan VK, Risacher SL, Stone DJ, Swaminathan S, Toga AW, Weiner MW, Saykin AJ. Genetic analysis of quantitative phenotypes in AD and MCI: imaging, cognition and biomarkers. Brain Imaging Behav. 2014 Jun; 8(2):183-207. PMID: 24092460.
    View in: PubMed
  62. Levey DF, Le-Niculescu H, Frank J, Ayalew M, Jain N, Kirlin B, Learman R, Winiger E, Rodd Z, Shekhar A, Schork N, Kiefer F, Kiefe F, Wodarz N, Müller-Myhsok B, Dahmen N. Genetic risk prediction and neurobiological understanding of alcoholism. Transl Psychiatry. 2014; 4:e391. PMID: 24844177.
    View in: PubMed
  63. Conway KP, Vullo GC, Kennedy AP, Finger MS, Agrawal A, Bjork JM, Farrer LA, Hancock DB, Hussong A, Wakim P, Huggins W, Hendershot T, Nettles DS, Pratt J, Maiese D, Junkins HA, Ramos EM, Strader LC, Hamilton CM, Sher KJ. Data compatibility in the addiction sciences: an examination of measure commonality. Drug Alcohol Depend. 2014 Aug 1; 141:153-8. PMID: 24954640.
    View in: PubMed
  64. Owen LA, Morrison MA, Ahn J, Woo SJ, Sato H, Robinson R, Morgan DJ, Zacharaki F, Simeonova M, Uehara H, Chakravarthy U, Hogg RE, Ambati BK, Kotoula M, Baehr W, Haider NB, Silvestri G, Miller JW, Tsironi EE, Farrer LA, Kim IK, Park KH, DeAngelis MM. FLT1 genetic variation predisposes to neovascular AMD in ethnically diverse populations and alters systemic FLT1 expression. Invest Ophthalmol Vis Sci. 2014 Jun; 55(6):3543-54. PMID: 24812550.
    View in: PubMed
  65. Farrer LA, Sherva R, Merkel PA, Siminovitch KA. Reply: To PMID 23740775. Arthritis Rheumatol. 2014 May; 66(5):1401. PMID: 24469994.
    View in: PubMed
  66. Nelson PT, Estus S, Abner EL, Parikh I, Malik M, Neltner JH, Ighodaro E, Wang WX, Wilfred BR, Wang LS, Kukull WA, Nandakumar K, Farman ML, Poon WW, Corrada MM, Kawas CH, Cribbs DH, Bennett DA, Schneider JA, Larson EB, Crane PK, Valladares O, Schmitt FA, Kryscio RJ, Jicha GA, Smith CD, Scheff SW, Sonnen JA, Haines JL, Pericak-Vance MA, Mayeux R, Farrer LA, Van Eldik LJ, Horbinski C, Green RC, Gearing M, Poon LW, Kramer PL, Woltjer RL, Montine TJ, Partch AB, Rajic AJ, Richmire K, Monsell SE. ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology. Acta Neuropathol. 2014; 127(6):825-43. PMID: 24770881.
    View in: PubMed
  67. Furman CD, Earnshaw LA, Doukas DJ, Farrer LA, Friedland RP. A case of inappropriate apolipoprotein e testing in Alzheimer's disease due to lack of an informed consent discussion. Am J Alzheimers Dis Other Demen. 2014 Nov; 29(7):590-5. PMID: 24615498.
    View in: PubMed
  68. Ruiz A, Heilmann S, Becker T, Hernández I, Wagner H, Thelen M, Mauleón A, Rosende-Roca M, Bellenguez C, Bis JC, Harold D, Gerrish A, Sims R, Sotolongo-Grau O, Espinosa A, Alegret M, Arrieta JL, Lacour A, Leber M, Becker J, Lafuente A, Ruiz S, Vargas L, Rodríguez O, Ortega G, Dominguez MA. Follow-up of loci from the International Genomics of Alzheimer's Disease Project identifies TRIP4 as a novel susceptibility gene. Transl Psychiatry. 2014; 4:e358. PMID: 24495969.
    View in: PubMed
  69. Jensen KP, Stein MB, Kranzler HR, Yang BZ, Farrer LA, Gelernter J. The a-endomannosidase gene (MANEA) is associated with panic disorder and social anxiety disorder. Transl Psychiatry. 2014; 4:e353. PMID: 24473444.
    View in: PubMed
  70. Benitez BA, Jin SC, Guerreiro R, Graham R, Lord J, Harold D, Sims R, Lambert JC, Gibbs JR, Bras J, Sassi C, Harari O, Bertelsen S, Lupton MK, Powell J, Bellenguez C, Brown K, Medway C, Haddick PC, van der Brug MP, Bhangale T, Ortmann W, Behrens T, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD, Haines JL, Turton J, Braae A, Barber I, Fagan AM, Holtzman DM, Morris JC. Missense variant in TREML2 protects against Alzheimer's disease. Neurobiol Aging. 2014 Jun; 35(6):1510.e19-26. PMID: 24439484.
    View in: PubMed
  71. Logue MW, Schu M, Vardarajan BN, Farrell J, Lunetta KL, Jun G, Baldwin CT, Deangelis MM, Farrer LA. Search for age-related macular degeneration risk variants in Alzheimer disease genes and pathways. Neurobiol Aging. 2014 Jun; 35(6):1510.e7-18. PMID: 24439028.
    View in: PubMed
  72. Yang C, Li C, Kranzler HR, Farrer LA, Zhao H, Gelernter J. Exploring the genetic architecture of alcohol dependence in African-Americans via analysis of a genomewide set of common variants. Hum Genet. 2014 May; 133(5):617-24. PMID: 24297757.
    View in: PubMed
  73. Wang LS, Jiao Y, Huang Y, Liu XY, Gibson G, Bennett B, Hamre KM, Li DW, Zhao HY, Gelernter J, Kranzler HR, Farrer LA, Lu L, Wang YJ, Gu WK. Critical evaluation of transcription factor Atf2 as a candidate modulator of alcohol preference in mouse and human populations. Genet Mol Res. 2013; 12(4):5992-6005. PMID: 24338393.
    View in: PubMed
  74. Han S, Yang BZ, Kranzler HR, Liu X, Zhao H, Farrer LA, Boerwinkle E, Potash JB, Gelernter J. Integrating GWASs and human protein interaction networks identifies a gene subnetwork underlying alcohol dependence. Am J Hum Genet. 2013 Dec 5; 93(6):1027-34. PMID: 24268660.
    View in: PubMed
  75. Li Y, Lu SH, Tsai CJ, Bohm C, Qamar S, Dodd RB, Meadows W, Jeon A, McLeod A, Chen F, Arimon M, Berezovska O, Hyman BT, Tomita T, Iwatsubo T, Johnson CM, Farrer LA, Schmitt-Ulms G, Fraser PE, St George-Hyslop PH. Structural interactions between inhibitor and substrate docking sites give insight into mechanisms of human PS1 complexes. Structure. 2014 Jan 7; 22(1):125-35. PMID: 24210759.
    View in: PubMed
  76. Gelernter J, Kranzler HR, Sherva R, Almasy L, Koesterer R, Smith AH, Anton R, Preuss UW, Ridinger M, Rujescu D, Wodarz N, Zill P, Zhao H, Farrer LA. Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci. Mol Psychiatry. 2014 Jan; 19(1):41-9. PMID: 24166409.
    View in: PubMed
  77. Lambert JC, Ibrahim-Verbaas CA, Harold D, Naj AC, Sims R, Bellenguez C, DeStafano AL, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thorton-Wells TA, Jones N, Smith AV, Chouraki V, Thomas C, Ikram MA, Zelenika D, Vardarajan BN, Kamatani Y, Lin CF, Gerrish A, Schmidt H, Kunkle B, Dunstan ML, Ruiz A, Bihoreau MT, Choi SH, Reitz C, Pasquier F, Cruchaga C, Craig D, Amin N, Berr C, Lopez OL, De Jager PL, Deramecourt V, Johnston JA, Evans D, Lovestone S, Letenneur L, Morón FJ, Rubinsztein DC, Eiriksdottir G, Sleegers K, Goate AM, Fiévet N, Huentelman MW, Gill M, Brown K, Kamboh MI, Keller L, Barberger-Gateau P, McGuiness B, Larson EB, Green R, Myers AJ, Dufouil C, Todd S, Wallon D, Love S, Rogaeva E, Gallacher J, St George-Hyslop P, Clarimon J, Lleo A, Bayer A, Tsuang DW, Yu L, Tsolaki M, Bossù P, Spalletta G, Proitsi P, Collinge J, Sorbi S, Sanchez-Garcia F, Fox NC, Hardy J, Deniz Naranjo MC, Bosco P, Clarke R, Brayne C, Galimberti D, Mancuso M, Matthews F. Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nat Genet. 2013 Dec; 45(12):1452-8. PMID: 24162737.
    View in: PubMed
  78. Gelernter J, Kranzler HR, Sherva R, Koesterer R, Almasy L, Zhao H, Farrer LA. Genome-wide association study of opioid dependence: multiple associations mapped to calcium and potassium pathways. Biol Psychiatry. 2014 Jul 1; 76(1):66-74. PMID: 24143882.
    View in: PubMed
  79. Zhan X, Larson DE, Wang C, Koboldt DC, Sergeev YV, Fulton RS, Fulton LL, Fronick CC, Branham KE, Bragg-Gresham J, Jun G, Hu Y, Kang HM, Liu D, Othman M, Brooks M, Ratnapriya R, Boleda A, Grassmann F, von Strachwitz C, Olson LM, Buitendijk GH, Hofman A, van Duijn CM, Cipriani V, Moore AT, Shahid H, Jiang Y, Conley YP, Morgan DJ, Kim IK, Johnson MP, Cantsilieris S, Richardson AJ, Guymer RH, Luo H, Ouyang H, Licht C, Pluthero FG, Zhang MM, Zhang K, Baird PN, Blangero J, Klein ML, Farrer LA, DeAngelis MM, Weeks DE, Gorin MB, Yates JR, Klaver CC, Pericak-Vance MA, Haines JL, Weber BH, Wilson RK, Heckenlively JR, Chew EY, Stambolian D, Mardis ER, Swaroop A, Abecasis GR. Identification of a rare coding variant in complement 3 associated with age-related macular degeneration. Nat Genet. 2013 Nov; 45(11):1375-9. PMID: 24036949.
    View in: PubMed
  80. Xie G, Roshandel D, Sherva R, Monach PA, Lu EY, Kung T, Carrington K, Zhang SS, Pulit SL, Ripke S, Carette S, Dellaripa PF, Edberg JC, Hoffman GS, Khalidi N, Langford CA, Mahr AD, St Clair EW, Seo P, Specks U, Spiera RF, Stone JH, Ytterberg SR, Raychaudhuri S, de Bakker PI, Farrer LA, Amos CI, Merkel PA, Siminovitch KA. Association of granulomatosis with polyangiitis (Wegener's) with HLA-DPB1*04 and SEMA6A gene variants: evidence from genome-wide analysis. Arthritis Rheum. 2013 Sep; 65(9):2457-68. PMID: 23740775.
    View in: PubMed
  81. Gelernter J, Sherva R, Koesterer R, Almasy L, Zhao H, Kranzler HR, Farrer L. Genome-wide association study of cocaine dependence and related traits: FAM53B identified as a risk gene. Mol Psychiatry. 2014 Jun; 19(6):717-23. PMID: 23958962.
    View in: PubMed
  82. Xie P, Kranzler HR, Krystal JH, Farrer LA, Zhao H, Gelernter J. Deep resequencing of 17 glutamate system genes identifies rare variants in DISC1 and GRIN2B affecting risk of opioid dependence. Addict Biol. 2014 Sep; 19(5):955-64. PMID: 23855403.
    View in: PubMed
  83. Schilling S, DeStefano AL, Sachdev PS, Choi SH, Mather KA, DeCarli CD, Wen W, Høgh P, Raz N, Au R, Beiser A, Wolf PA, Romero JR, Zhu YC, Lunetta KL, Farrer L, Dufouil C, Kuller LH, Mazoyer B, Seshadri S, Tzourio C, Debette S. APOE genotype and MRI markers of cerebrovascular disease: systematic review and meta-analysis. Neurology. 2013 Jul 16; 81(3):292-300. PMID: 23858411.
    View in: PubMed
  84. Nho K, Corneveaux JJ, Kim S, Lin H, Risacher SL, Shen L, Swaminathan S, Ramanan VK, Liu Y, Foroud T, Inlow MH, Siniard AL, Reiman RA, Aisen PS, Petersen RC, Green RC, Jack CR, Weiner MW, Baldwin CT, Lunetta K, Farrer LA. Identification of functional variants from whole-exome sequencing, combined with neuroimaging genetics. Mol Psychiatry. 2013 Jul; 18(7):739. PMID: 23787478.
    View in: PubMed
  85. Xie P, Kranzler HR, Yang C, Zhao H, Farrer LA, Gelernter J. Genome-wide association study identifies new susceptibility loci for posttraumatic stress disorder. Biol Psychiatry. 2013 Nov 1; 74(9):656-63. PMID: 23726511.
    View in: PubMed
  86. Reitz C, Tosto G, Vardarajan B, Rogaeva E, Ghani M, Rogers RS, Conrad C, Haines JL, Pericak-Vance MA, Fallin MD, Foroud T, Farrer LA, Schellenberg GD, George-Hyslop PS, Mayeux R. Independent and epistatic effects of variants in VPS10-d receptors on Alzheimer disease risk and processing of the amyloid precursor protein (APP). Transl Psychiatry. 2013; 3:e256. PMID: 23673467.
    View in: PubMed
  87. Nho K, Corneveaux JJ, Kim S, Lin H, Risacher SL, Shen L, Swaminathan S, Ramanan VK, Liu Y, Foroud T, Inlow MH, Siniard AL, Reiman RA, Aisen PS, Petersen RC, Green RC, Jack CR, Weiner MW, Baldwin CT, Lunetta K, Farrer LA. Whole-exome sequencing and imaging genetics identify functional variants for rate of change in hippocampal volume in mild cognitive impairment. Mol Psychiatry. 2013 Jul; 18(7):781-7. PMID: 23608917.
    View in: PubMed
  88. Reitz C, Jun G, Naj A, Rajbhandary R, Vardarajan BN, Wang LS, Valladares O, Lin CF, Larson EB, Graff-Radford NR, Evans D, De Jager PL, Crane PK, Buxbaum JD, Murrell JR, Raj T, Ertekin-Taner N, Logue M, Baldwin CT, Green RC, Barnes LL, Cantwell LB, Fallin MD, Go RC, Griffith P, Obisesan TO, Manly JJ, Lunetta KL, Kamboh MI, Lopez OL, Bennett DA, Hendrie H, Hall KS, Goate AM, Byrd GS, Kukull WA, Foroud TM, Haines JL, Farrer LA, Pericak-Vance MA, Schellenberg GD, Mayeux R. Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ?4,and the risk of late-onset Alzheimer disease in African Americans. JAMA. 2013 Apr 10; 309(14):1483-92. PMID: 23571587.
    View in: PubMed
  89. Cruchaga C, Kauwe JS, Harari O, Jin SC, Cai Y, Karch CM, Benitez BA, Jeng AT, Skorupa T, Carrell D, Bertelsen S, Bailey M, McKean D, Shulman JM, De Jager PL, Chibnik L, Bennett DA, Arnold SE, Harold D, Sims R, Gerrish A, Williams J, Van Deerlin VM, Lee VM, Shaw LM, Trojanowski JQ, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD, Peskind ER, Galasko D, Fagan AM, Holtzman DM, Morris JC. GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease. Neuron. 2013 Apr 24; 78(2):256-68. PMID: 23562540.
    View in: PubMed
  90. Miyashita A, Koike A, Jun G, Wang LS, Takahashi S, Matsubara E, Kawarabayashi T, Shoji M, Tomita N, Arai H, Asada T, Harigaya Y, Ikeda M, Amari M, Hanyu H, Higuchi S, Ikeuchi T, Nishizawa M, Suga M, Kawase Y, Akatsu H, Kosaka K, Yamamoto T, Imagawa M, Hamaguchi T, Yamada M, Moriaha T, Takeda M, Takao T, Nakata K, Fujisawa Y, Sasaki K, Watanabe K, Nakashima K, Urakami K, Ooya T, Takahashi M, Yuzuriha T, Serikawa K, Yoshimoto S, Nakagawa R, Kim JW, Ki CS, Won HH, Na DL, Seo SW, Mook-Jung I. SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians. PLoS One. 2013; 8(4):e58618. PMID: 23565137.
    View in: PubMed
  91. Sherva R, Tripodis Y, Bennett DA, Chibnik LB, Crane PK, de Jager PL, Farrer LA, Saykin AJ, Shulman JM, Naj A, Green RC. Genome-wide association study of the rate of cognitive decline in Alzheimer's disease. Alzheimers Dement. 2014 Jan; 10(1):45-52. PMID: 23535033.
    View in: PubMed
  92. Ngo D, Bae H, Steinberg MH, Sebastiani P, Solovieff N, Baldwin CT, Melista E, Safaya S, Farrer LA, Al-Suliman AM, Albuali WH, Al Bagshi MH, Naserullah Z, Akinsheye I, Gallagher P, Luo HY, Chui DH, Farrell JJ, Al-Ali AK, Alsultan A. Fetal hemoglobin in sickle cell anemia: genetic studies of the Arab-Indian haplotype. Blood Cells Mol Dis. 2013 Jun; 51(1):22-6. PMID: 23465615.
    View in: PubMed
  93. Fritsche LG, Chen W, Schu M, Yaspan BL, Yu Y, Thorleifsson G, Zack DJ, Arakawa S, Cipriani V, Ripke S, Igo RP, Buitendijk GH, Sim X, Weeks DE, Guymer RH, Merriam JE, Francis PJ, Hannum G, Agarwal A, Armbrecht AM, Audo I, Aung T, Barile GR, Benchaboune M, Bird AC, Bishop PN, Branham KE, Brooks M, Brucker AJ, Cade WH, Cain MS, Campochiaro PA, Chan CC, Cheng CY, Chew EY, Chin KA, Chowers I, Clayton DG, Cojocaru R, Conley YP, Cornes BK, Daly MJ, Dhillon B, Edwards AO, Evangelou E, Fagerness J, Ferreyra HA, Friedman JS, Geirsdottir A, George RJ, Gieger C, Gupta N, Hagstrom SA, Harding SP, Haritoglou C, Heckenlively JR, Holz FG, Hughes G, Ioannidis JP, Ishibashi T, Joseph P, Jun G, Kamatani Y, Katsanis N, N Keilhauer C, Khan JC, Kim IK, Kiyohara Y, Klein BE, Klein R, Kovach JL, Kozak I, Lee CJ, Lee KE, Lichtner P, Lotery AJ, Meitinger T, Mitchell P, Mohand-Saïd S, Moore AT, Morgan DJ, Morrison MA, Myers CE, Naj AC, Nakamura Y, Okada Y, Orlin A, Ortube MC, Othman MI, Pappas C, Park KH, Pauer GJ, Peachey NS, Poch O, Priya RR, Reynolds R, Richardson AJ, Ripp R, Rudolph G, Ryu E, Sahel JA, Schaumberg DA, Scholl HP, Schwartz SG, Scott WK, Shahid H, Sigurdsson H, Silvestri G, Sivakumaran TA, Smith RT, Sobrin L, Souied EH, Stambolian DE, Stefansson H, Sturgill-Short GM, Takahashi A, Tosakulwong N, Truitt BJ, Tsironi EE, Uitterlinden AG, van Duijn CM, Vijaya L, Vingerling JR, Vithana EN, Webster AR, Wichmann HE, Winkler TW, Wong TY, Wright AF, Zelenika D, Zhang M, Zhao L, Zhang K, Klein ML, Hageman GS, Lathrop GM, Stefansson K, Allikmets R, Baird PN, Gorin MB, Wang JJ, Klaver CC, Seddon JM, Pericak-Vance MA, Iyengar SK, Yates JR, Swaroop A, Weber BH, Kubo M, Deangelis MM, Léveillard T, Thorsteinsdottir U, Haines JL, Farrer LA, Heid IM, Abecasis GR. Seven new loci associated with age-related macular degeneration. Nat Genet. 2013 Apr; 45(4):433-9, 439e1-2. PMID: 23455636.
    View in: PubMed
  94. Inzelberg R, Afgin AE, Massarwa M, Schechtman E, Israeli-Korn SD, Strugatsky R, Abuful A, Kravitz E, Farrer LA, Friedland RP. Prayer at midlife is associated with reduced risk of cognitive decline in Arabic women. Curr Alzheimer Res. 2013 Mar; 10(3):340-6. PMID: 23116476.
    View in: PubMed
  95. Vardarajan B, Vergote D, Tissir F, Logue M, Yang J, Daude N, Ando K, Rogaeva E, Lee J, Cheng R, Brion JP, Ghani M, Shi B, Baldwin CT, Kar S, Mayeux R, Fraser P, Goffinet AM, George-Hyslop PS, Farrer LA, Westaway D. Role of p73 in Alzheimer disease: lack of association in mouse models or in human cohorts. Mol Neurodegener. 2013; 8:10. PMID: 23414597.
    View in: PubMed
  96. Holton P, Ryten M, Nalls M, Trabzuni D, Weale ME, Hernandez D, Crehan H, Gibbs JR, Mayeux R, Haines JL, Farrer LA, Pericak-Vance MA, Schellenberg GD. Initial assessment of the pathogenic mechanisms of the recently identified Alzheimer risk Loci. Ann Hum Genet. 2013 Mar; 77(2):85-105. PMID: 23360175.
    View in: PubMed
  97. Zayats T, Yang BZ, Xie P, Poling J, Farrer LA, Gelernter J. A complex interplay between personality domains, marital status and a variant in CHRNA5 on the risks of cocaine, nicotine dependences and cocaine-induced paranoia. PLoS One. 2013; 8(1):e49368. PMID: 23308091.
    View in: PubMed
  98. Whitcomb DC, LaRusch J, Krasinskas AM, Klei L, Smith JP, Brand RE, Neoptolemos JP, Lerch MM, Tector M, Sandhu BS, Guda NM, Orlichenko L. Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis. Nat Genet. 2012 Dec; 44(12):1349-54. PMID: 23143602.
    View in: PubMed
  99. Friedland RP, Shah JJ, Farrer LA, Vardarajan B, Rebolledo-Mendez JD, Mok K, Hardy J. Behavioral variant frontotemporal lobar degeneration with amyotrophic lateral sclerosis with a chromosome 9p21 hexanucleotide repeat. Front Neurol. 2012; 3:136. PMID: 23060854.
    View in: PubMed
  100. Jun G, Vardarajan BN, Buros J, Yu CE, Hawk MV, Dombroski BA, Crane PK, Larson EB. Comprehensive search for Alzheimer disease susceptibility loci in the APOE region. Arch Neurol. 2012 Oct; 69(10):1270-9. PMID: 22869155.
    View in: PubMed
  101. Jun G, Moncaster JA, Koutras C, Seshadri S, Buros J, McKee AC, Levesque G, Wolf PA, St George-Hyslop P, Goldstein LE, Farrer LA. d-Catenin is genetically and biologically associated with cortical cataract and future Alzheimer-related structural and functional brain changes. PLoS One. 2012; 7(9):e43728. PMID: 22984439.
    View in: PubMed
  102. Peer K, Rennert L, Lynch KG, Farrer L, Gelernter J, Kranzler HR. Prevalence of DSM-IV and DSM-5 alcohol, cocaine, opioid, and cannabis use disorders in a largely substance dependent sample. Drug Alcohol Depend. 2013 Jan 1; 127(1-3):215-9. PMID: 22884164.
    View in: PubMed
  103. Melville SA, Buros J, Parrado AR, Vardarajan B, Logue MW, Shen L, Risacher SL, Kim S, Jun G, DeCarli C, Lunetta KL, Baldwin CT, Saykin AJ, Farrer LA. Multiple loci influencing hippocampal degeneration identified by genome scan. Ann Neurol. 2012 Jul; 72(1):65-75. PMID: 22745009.
    View in: PubMed
  104. Allen M, Zou F, Chai HS, Younkin CS, Crook J, Pankratz VS, Carrasquillo MM, Rowley CN, Nair AA, Middha S, Maharjan S, Nguyen T, Ma L, Malphrus KG, Palusak R, Lincoln S, Bisceglio G, Georgescu C, Schultz D, Rakhshan F, Kolbert CP, Jen J, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD. Novel late-onset Alzheimer disease loci variants associate with brain gene expression. Neurology. 2012 Jul 17; 79(3):221-8. PMID: 22722634.
    View in: PubMed
  105. Xie P, Kranzler HR, Farrer L, Gelernter J. Serotonin transporter 5-HTTLPR genotype moderates the effects of childhood adversity on posttraumatic stress disorder risk: a replication study. Am J Med Genet B Neuropsychiatr Genet. 2012 Sep; 159B(6):644-52. PMID: 22693124.
    View in: PubMed
  106. Zou F, Chai HS, Younkin CS, Allen M, Crook J, Pankratz VS, Carrasquillo MM, Rowley CN, Nair AA, Middha S, Maharjan S, Nguyen T, Ma L, Malphrus KG, Palusak R, Lincoln S, Bisceglio G, Georgescu C, Kouri N, Kolbert CP, Jen J, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD. Brain expression genome-wide association study (eGWAS) identifies human disease-associated variants. PLoS Genet. 2012; 8(6):e1002707. PMID: 22685416.
    View in: PubMed
  107. Vardarajan BN, Bruesegem SY, Harbour ME, Inzelberg R, Friedland R, St George-Hyslop P, Seaman MN, Farrer LA. Identification of Alzheimer disease-associated variants in genes that regulate retromer function. Neurobiol Aging. 2012 Sep; 33(9):2231.e15-2231.e30. PMID: 22673115.
    View in: PubMed
  108. Alsultan A, Ngo DA, Farrell JJ, Akinsheye I, Solovieff N, Ghabbour HA, Al-Ali A, Alsuliman A, Al-Baghshi M, Albu-Ali W, Alabdulaali M, Baldwin CT, Farrer LA, Luo H, Melista E, Safaya S, Nwaru M, Chui DH, Steinberg MH. A functional promoter polymorphism of the d-globin gene is a specific marker of the Arab-Indian haplotype. Am J Hematol. 2012 Aug; 87(8):824-6. PMID: 22641479.
    View in: PubMed
  109. Sun J, Bi J, Chan G, Oslin D, Farrer L, Gelernter J, Kranzler HR. Improved methods to identify stable, highly heritable subtypes of opioid use and related behaviors. Addict Behav. 2012 Oct; 37(10):1138-44. PMID: 22694982.
    View in: PubMed
  110. Kamboh MI, Demirci FY, Wang X, Minster RL, Carrasquillo MM, Pankratz VS, Younkin SG, Saykin AJ. Genome-wide association study of Alzheimer's disease. Transl Psychiatry. 2012; 2:e117. PMID: 22832961.
    View in: PubMed
  111. Coppola G, Chinnathambi S, Lee JJ, Dombroski BA, Baker MC, Soto-Ortolaza AI, Lee SE, Klein E, Huang AY, Sears R, Lane JR, Karydas AM, Kenet RO, Biernat J, Wang LS, Cotman CW, Decarli CS, Levey AI, Ringman JM, Mendez MF, Chui HC, Le Ber I, Brice A, Lupton MK, Preza E, Lovestone S, Powell J, Graff-Radford N, Petersen RC, Boeve BF, Lippa CF, Bigio EH, Mackenzie I, Finger E, Kertesz A, Caselli RJ, Gearing M, Juncos JL, Ghetti B, Spina S, Bordelon YM, Tourtellotte WW, Frosch MP, Vonsattel JP, Zarow C, Beach TG, Albin RL, Lieberman AP, Lee VM, Trojanowski JQ, Van Deerlin VM, Bird TD, Galasko DR, Masliah E, White CL, Troncoso JC, Hannequin D, Boxer AL, Geschwind MD, Kumar S, Mandelkow EM, Wszolek ZK, Uitti RJ, Dickson DW, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA. Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases. Hum Mol Genet. 2012 Aug 1; 21(15):3500-12. PMID: 22556362.
    View in: PubMed
  112. Han S, Yang BZ, Kranzler HR, Oslin D, Anton R, Farrer LA, Gelernter J. Linkage analysis followed by association show NRG1 associated with cannabis dependence in African Americans. Biol Psychiatry. 2012 Oct 15; 72(8):637-44. PMID: 22520967.
    View in: PubMed
  113. Chen XD, Xiong DH, Yang TL, Pei YF, Guo YF, Li J, Yang F, Pan F, Tan LJ, Yan H, Liu XG, Lei SF, Li X, Ning LL, Zhu XZ, Levy S, Kranzler HR, Farrer LA, Gelernter J, Recker RR, Deng HW. ANKRD7 and CYTL1 are novel risk genes for alcohol drinking behavior. Chin Med J (Engl). 2012 Mar; 125(6):1127-34. PMID: 22613542.
    View in: PubMed
  114. Yang BZ, Han S, Kranzler HR, Farrer LA, Elston RC, Gelernter J. Autosomal linkage scan for loci predisposing to comorbid dependence on multiple substances. Am J Med Genet B Neuropsychiatr Genet. 2012 Jun; 159B(4):361-9. PMID: 22354695.
    View in: PubMed
  115. Li D, Zhao H, Kranzler HR, Oslin D, Anton RF, Farrer LA, Gelernter J. Association of COL25A1 with comorbid antisocial personality disorder and substance dependence. Biol Psychiatry. 2012 Apr 15; 71(8):733-40. PMID: 22297151.
    View in: PubMed
  116. Farrer L, Logue M. Collection of clinical and epidemiological data for genetic linkage and association studies. Curr Protoc Hum Genet. 2012 Jan; Chapter 1:Unit1.1. PMID: 22241654.
    View in: PubMed
  117. Afgin AE, Massarwa M, Schechtman E, Israeli-Korn SD, Strugatsky R, Abuful A, Farrer LA, Friedland RP, Inzelberg R. High prevalence of mild cognitive impairment and Alzheimer's disease in arabic villages in northern Israel: impact of gender and education. J Alzheimers Dis. 2012; 29(2):431-9. PMID: 22233764.
    View in: PubMed
  118. Chen J, Brunzell DH, Jackson K, van der Vaart A, Ma JZ, Payne TJ, Sherva R, Farrer LA, Gejman P, Levinson DF, Holmans P, Aggen SH, Damaj I, Kuo PH, Webb BT, Anton R, Kranzler HR, Gelernter J, Li MD, Kendler KS, Chen X. ACSL6 is associated with the number of cigarettes smoked and its expression is altered by chronic nicotine exposure. PLoS One. 2011; 6(12):e28790. PMID: 22205969.
    View in: PubMed
  119. Arias AJ, Chan G, Gelernter J, Farrer L, Kranzler HR. Variation in OPRM1 and risk of suicidal behavior in drug-dependent individuals. Am J Addict. 2012 Jan-Feb; 21(1):5-10. PMID: 22211341.
    View in: PubMed
  120. Logue MW, Schu M, Vardarajan BN, Buros J, Green RC, Go RC, Griffith P, Obisesan TO, Shatz R, Borenstein A, Cupples LA, Lunetta KL, Fallin MD, Baldwin CT, Farrer LA. A comprehensive genetic association study of Alzheimer disease in African Americans. Arch Neurol. 2011 Dec; 68(12):1569-79. PMID: 22159054.
    View in: PubMed
  121. Granada M, Wilk JB, Tuzova M, Strachan DP, Weidinger S, Albrecht E, Gieger C, Heinrich J, Himes BE, Hunninghake GM, Celedón JC, Weiss ST, Cruikshank WW, Farrer LA, Center DM, O'Connor GT. A genome-wide association study of plasma total IgE concentrations in the Framingham Heart Study. J Allergy Clin Immunol. 2012 Mar; 129(3):840-845.e21. PMID: 22075330.
    View in: PubMed
  122. Xie P, Kranzler HR, Zhang H, Oslin D, Anton RF, Farrer LA, Gelernter J. Childhood adversity increases risk for nicotine dependence and interacts with a5 nicotinic acetylcholine receptor genotype specifically in males. Neuropsychopharmacology. 2012 Feb; 37(3):669-76. PMID: 22012472.
    View in: PubMed
  123. Kranzler HR, Feinn R, Nelson EC, Covault J, Anton RF, Farrer L, Gelernter J. A CRHR1 haplotype moderates the effect of adverse childhood experiences on lifetime risk of major depressive episode in African-American women. Am J Med Genet B Neuropsychiatr Genet. 2011 Dec; 156B(8):960-8. PMID: 21998007.
    View in: PubMed
  124. Jun G, Nicolaou M, Morrison MA, Buros J, Morgan DJ, Radeke MJ, Yonekawa Y, Tsironi EE, Kotoula MG, Zacharaki F, Mollema N, Yuan Y, Miller JW, Haider NB, Hageman GS, Kim IK, Schaumberg DA, Farrer LA, DeAngelis MM. Influence of ROBO1 and RORA on risk of age-related macular degeneration reveals genetically distinct phenotypes in disease pathophysiology. PLoS One. 2011; 6(10):e25775. PMID: 21998696.
    View in: PubMed
  125. Morrison MA, Silveira AC, Huynh N, Jun G, Smith SE, Zacharaki F, Sato H, Loomis S, Andreoli MT, Adams SM, Radeke MJ, Jelcick AS, Yuan Y, Tsiloulis AN, Chatzoulis DZ, Silvestri G, Kotoula MG, Tsironi EE, Hollis BW, Chen R, Haider NB, Miller JW, Farrer LA, Hageman GS, Kim IK, Schaumberg DA, DeAngelis MM. Systems biology-based analysis implicates a novel role for vitamin D metabolism in the pathogenesis of age-related macular degeneration. Hum Genomics. 2011 Oct; 5(6):538-68. PMID: 22155603.
    View in: PubMed
  126. Douglas K, Chan G, Gelernter J, Arias AJ, Anton RF, Poling J, Farrer L, Kranzler HR. 5-HTTLPR as a potential moderator of the effects of adverse childhood experiences on risk of antisocial personality disorder. Psychiatr Genet. 2011 Oct; 21(5):240-8. PMID: 21399568.
    View in: PubMed
  127. Ittiwut C, Yang BZ, Kranzler HR, Anton RF, Hirunsatit R, Weiss RD, Covault J, Farrer LA, Gelernter J. GABRG1 and GABRA2 variation associated with alcohol dependence in African Americans. Alcohol Clin Exp Res. 2012 Apr; 36(4):588-93. PMID: 21919924.
    View in: PubMed
  128. Chang SC, Xie P, Anton RF, De Vivo I, Farrer LA, Kranzler HR, Oslin D, Purcell SM, Roberts AL, Smoller JW, Uddin M, Gelernter J, Koenen KC. No association between ADCYAP1R1 and post-traumatic stress disorder in two independent samples. Mol Psychiatry. 2012 Mar; 17(3):239-41. PMID: 21912390.
    View in: PubMed
  129. Yang BZ, Han S, Kranzler HR, Farrer LA, Gelernter J. A genomewide linkage scan of cocaine dependence and major depressive episode in two populations. Neuropsychopharmacology. 2011 Nov; 36(12):2422-30. PMID: 21849985.
    View in: PubMed
  130. Hamilton CM, Strader LC, Pratt JG, Maiese D, Hendershot T, Kwok RK, Hammond JA, Huggins W, Jackman D, Pan H, Nettles DS, Beaty TH, Farrer LA, Kraft P, Marazita ML, Ordovas JM, Pato CN, Spitz MR, Wagener D, Williams M, Junkins HA, Harlan WR, Ramos EM, Haines J. The PhenX Toolkit: get the most from your measures. Am J Epidemiol. 2011 Aug 1; 174(3):253-60. PMID: 21749974.
    View in: PubMed
  131. Hamilton CM, Strader LC, Pratt JG, Maiese D, Hendershot T, Kwok RK, Hammond JA, Huggins W, Jackman D, Pan H, Nettles DS, Beaty TH, Farrer LA, Kraft P, Marazita ML, Ordovas JM, Pato CN, Spitz MR, Wagener D, Williams M, Junkins HA, Harlan WR, Ramos EM, Haines J. Hamilton et al. Respond to "Consolidating Data Harmonization" Am J Epidemiol. 2011 Jul 11. PMID: 21749970.
    View in: PubMed
  132. Logue MW, Posner H, Green RC, Moline M, Cupples LA, Lunetta KL, Zou H, Hurt SW, Farrer LA, Decarli C. Magnetic resonance imaging-measured atrophy and its relationship to cognitive functioning in vascular dementia and Alzheimer's disease patients. Alzheimers Dement. 2011 Sep; 7(5):493-500. PMID: 21723205.
    View in: PubMed
  133. Xie P, Kranzler HR, Krauthammer M, Cosgrove KP, Oslin D, Anton RF, Farrer LA, Picciotto MR, Krystal JH, Zhao H, Gelernter J. Rare nonsynonymous variants in alpha-4 nicotinic acetylcholine receptor gene protect against nicotine dependence. Biol Psychiatry. 2011 Sep 15; 70(6):528-36. PMID: 21683344.
    View in: PubMed
  134. Ittiwut R, Listman JB, Ittiwut C, Cubells JF, Weiss RD, Brady K, Oslin D, Farrer LA, Kranzler HR, Gelernter J. Association between polymorphisms in catechol-O-methyltransferase (COMT) and cocaine-induced paranoia in European-American and African-American populations. Am J Med Genet B Neuropsychiatr Genet. 2011 Sep; 156B(6):651-60. PMID: 21656904.
    View in: PubMed
  135. Reitz C, Rogaeva E, Foroud T, Farrer LA. Genetics and genomics of late-onset Alzheimer's disease and its endophenotypes. Int J Alzheimers Dis. 2011; 2011:284728. PMID: 21660206.
    View in: PubMed
  136. Solovieff N, Hartley SW, Baldwin CT, Klings ES, Gladwin MT, Taylor JG, Kato GJ, Farrer LA, Steinberg MH, Sebastiani P. Ancestry of African Americans with sickle cell disease. Blood Cells Mol Dis. 2011 Jun 15; 47(1):41-5. PMID: 21546286.
    View in: PubMed
  137. Hodoglugil U, Williamson DW, Yu Y, Farrer LA, Mahley RW. Glucuronic acid epimerase is associated with plasma triglyceride and high-density lipoprotein cholesterol levels in Turks. Ann Hum Genet. 2011 May; 75(3):398-417. PMID: 21488854.
    View in: PubMed
  138. Chan G, Gelernter J, Oslin D, Farrer L, Kranzler HR. Empirically derived subtypes of opioid use and related behaviors. Addiction. 2011 Jun; 106(6):1146-54. PMID: 21306596.
    View in: PubMed
  139. Naj AC, Jun G, Beecham GW, Wang LS, Vardarajan BN, Buros J, Gallins PJ, Buxbaum JD, Jarvik GP, Crane PK, Larson EB, Bird TD, Boeve BF, Graff-Radford NR, De Jager PL, Evans D, Schneider JA, Carrasquillo MM, Ertekin-Taner N, Younkin SG, Cruchaga C, Kauwe JS, Nowotny P, Kramer P, Hardy J, Huentelman MJ, Myers AJ, Barmada MM, Demirci FY, Baldwin CT, Green RC, Rogaeva E, St George-Hyslop P, Arnold SE, Barber R, Beach T, Bigio EH, Bowen JD, Boxer A, Burke JR, Cairns NJ, Carlson CS, Carney RM, Carroll SL, Chui HC, Clark DG, Corneveaux J, Cotman CW, Cummings JL, DeCarli C, DeKosky ST, Diaz-Arrastia R, Dick M, Dickson DW, Ellis WG, Faber KM, Fallon KB, Farlow MR, Ferris S, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Gilman S, Giordani B, Glass JD, Growdon JH, Hamilton RL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jicha GA, Jin LW, Johnson N, Karlawish J, Karydas A, Kaye JA, Kim R, Koo EH, Kowall NW, Lah JJ, Levey AI, Lieberman AP, Lopez OL, Mack WJ, Marson DC, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Parisi JE, Perl DP, Peskind E, Petersen RC, Poon WW, Quinn JF, Rajbhandary RA, Raskind M, Reisberg B, Ringman JM, Roberson ED, Rosenberg RN, Sano M, Schneider LS, Seeley W, Shelanski ML, Slifer MA, Smith CD, Sonnen JA, Spina S, Stern RA, Tanzi RE, Trojanowski JQ, Troncoso JC, Van Deerlin VM, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Williamson J, Woltjer RL, Cantwell LB, Dombroski BA, Beekly D, Lunetta KL, Martin ER, Kamboh MI, Saykin AJ, Reiman EM, Bennett DA, Morris JC, Montine TJ, Goate AM, Blacker D, Tsuang DW, Hakonarson H, Kukull WA, Foroud TM, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD. Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat Genet. 2011 May; 43(5):436-41. PMID: 21460841.
    View in: PubMed
  140. Sherva R, Farrer LA. Power and pitfalls of the genome-wide association study approach to identify genes for Alzheimer's disease. Curr Psychiatry Rep. 2011 Apr; 13(2):138-46. PMID: 21312009.
    View in: PubMed
  141. Farrell JJ, Sherva RM, Chen ZY, Luo HY, Chu BF, Ha SY, Li CK, Lee AC, Li RC, Li CK, Yuen HL, So JC, Ma ES, Chan LC, Chan V, Sebastiani P, Farrer LA, Baldwin CT, Steinberg MH, Chui DH. A 3-bp deletion in the HBS1L-MYB intergenic region on chromosome 6q23 is associated with HbF expression. Blood. 2011 May 5; 117(18):4935-45. PMID: 21385855.
    View in: PubMed
  142. Leventhal AM, Gelernter J, Oslin D, Anton RF, Farrer LA, Kranzler HR. Agitated depression in substance dependence. Drug Alcohol Depend. 2011 Jul 1; 116(1-3):163-9. PMID: 21277711.
    View in: PubMed
  143. Reitz C, Cheng R, Rogaeva E, Lee JH, Tokuhiro S, Zou F, Bettens K, Sleegers K, Tan EK, Kimura R, Shibata N, Arai H, Kamboh MI, Prince JA, Maier W, Riemenschneider M, Owen M, Harold D, Hollingworth P, Cellini E, Sorbi S, Nacmias B, Takeda M, Pericak-Vance MA, Haines JL, Younkin S, Williams J, van Broeckhoven C, Farrer LA, St George-Hyslop PH, Mayeux R. Meta-analysis of the association between variants in SORL1 and Alzheimer disease. Arch Neurol. 2011 Jan; 68(1):99-106. PMID: 21220680.
    View in: PubMed
  144. Sherva R, Baldwin CT, Inzelberg R, Vardarajan B, Cupples LA, Lunetta K, Bowirrat A, Naj A, Pericak-Vance M, Friedland RP, Farrer LA. Identification of novel candidate genes for Alzheimer's disease by autozygosity mapping using genome wide SNP data. J Alzheimers Dis. 2011; 23(2):349-59. PMID: 21098978.
    View in: PubMed
  145. Reitz C, Tokuhiro S, Clark LN, Conrad C, Vonsattel JP, Hazrati LN, Palotás A, Lantigua R, Medrano M, Z Jiménez-Velázquez I, Vardarajan B, Simkin I, Haines JL, Pericak-Vance MA, Farrer LA, Lee JH, Rogaeva E, George-Hyslop PS, Mayeux R. SORCS1 alters amyloid precursor protein processing and variants may increase Alzheimer's disease risk. Ann Neurol. 2011 Jan; 69(1):47-64. PMID: 21280075.
    View in: PubMed
  146. Khachaturian AS, Chapman J, Farrer L, Friedland RP, Ebstein R, Grossman I, Hendler T, Hermann B, Inzelberg R, Johnson S, Khachaturian ZS, Lichter-Shapira I, Makeeva O, Mayrl R, Mizrahi E, Roses AD, Sager M, Fraifeld S. Healthy aging and preclinical dementia: the United States-Israel Longitudinal Database project. Alzheimers Dement. 2010 Nov; 6(6):475-81. PMID: 21044777.
    View in: PubMed
  147. Erlich PM, Lunetta KL, Cupples LA, Abraham CR, Green RC, Baldwin CT, Farrer LA. Serum paraoxonase activity is associated with variants in the PON gene cluster and risk of Alzheimer disease. Neurobiol Aging. 2012 May; 33(5):1015.e7-23. PMID: 20980077.
    View in: PubMed
  148. Jun G, Naj AC, Beecham GW, Wang LS, Buros J, Gallins PJ, Buxbaum JD, Ertekin-Taner N, Fallin MD, Friedland R, Inzelberg R, Kramer P, Rogaeva E, St George-Hyslop P. Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes. Arch Neurol. 2010 Dec; 67(12):1473-84. PMID: 20697030.
    View in: PubMed
  149. Perneczky R, Wagenpfeil S, Lunetta KL, Cupples LA, Green RC, Decarli C, Farrer LA, Kurz A. Head circumference, atrophy, and cognition: implications for brain reserve in Alzheimer disease. Neurology. 2010 Jul 13; 75(2):137-42. PMID: 20625166.
    View in: PubMed
  150. Sherva R, Kranzler HR, Yu Y, Logue MW, Poling J, Arias AJ, Anton RF, Oslin D, Farrer LA, Gelernter J. Variation in nicotinic acetylcholine receptor genes is associated with multiple substance dependence phenotypes. Neuropsychopharmacology. 2010 Aug; 35(9):1921-31. PMID: 20485328.
    View in: PubMed
  151. Seshadri S, Fitzpatrick AL, Ikram MA, DeStefano AL, Gudnason V, Boada M, Bis JC, Smith AV, Carassquillo MM, Lambert JC, Harold D, Schrijvers EM, Ramirez-Lorca R, Debette S, Longstreth WT, Janssens AC, Pankratz VS, Dartigues JF, Hollingworth P, Aspelund T, Hernandez I, Beiser A, Kuller LH, Koudstaal PJ, Dickson DW, Tzourio C, Abraham R, Antunez C, Du Y, Rotter JI, Aulchenko YS, Harris TB, Petersen RC, Berr C, Owen MJ, Lopez-Arrieta J, Varadarajan BN, Becker JT, Rivadeneira F, Nalls MA, Graff-Radford NR, Campion D, Auerbach S, Rice K, Hofman A, Jonsson PV, Schmidt H, Lathrop M, Mosley TH, Au R, Psaty BM, Uitterlinden AG, Farrer LA, Lumley T, Ruiz A, Williams J, Amouyel P, Younkin SG, Wolf PA, Launer LJ, Lopez OL, van Duijn CM, Breteler MM. Genome-wide analysis of genetic loci associated with Alzheimer disease. JAMA. 2010 May 12; 303(18):1832-40. PMID: 20460622.
    View in: PubMed
  152. Saykin AJ, Shen L, Foroud TM, Potkin SG, Swaminathan S, Kim S, Risacher SL, Nho K, Huentelman MJ, Craig DW, Thompson PM, Stein JL, Moore JH, Farrer LA, Green RC, Bertram L, Jack CR, Weiner MW. Alzheimer's Disease Neuroimaging Initiative biomarkers as quantitative phenotypes: Genetics core aims, progress, and plans. Alzheimers Dement. 2010 May; 6(3):265-73. PMID: 20451875.
    View in: PubMed
  153. Xie P, Kranzler HR, Poling J, Stein MB, Anton RF, Farrer LA, Gelernter J. Interaction of FKBP5 with childhood adversity on risk for post-traumatic stress disorder. Neuropsychopharmacology. 2010 Jul; 35(8):1684-92. PMID: 20393453.
    View in: PubMed
  154. Chen W, Stambolian D, Edwards AO, Branham KE, Othman M, Jakobsdottir J, Tosakulwong N, Pericak-Vance MA, Campochiaro PA, Klein ML, Tan PL, Conley YP, Kanda A, Kopplin L, Li Y, Augustaitis KJ, Karoukis AJ, Scott WK, Agarwal A, Kovach JL, Schwartz SG, Postel EA, Brooks M, Baratz KH, Brown WL. Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration. Proc Natl Acad Sci U S A. 2010 Apr 20; 107(16):7401-6. PMID: 20385819.
    View in: PubMed
  155. Sherva R, Sripichai O, Abel K, Ma Q, Whitacre J, Angkachatchai V, Makarasara W, Winichagoon P, Svasti S, Fucharoen S, Braun A, Farrer LA. Genetic modifiers of Hb E/beta0 thalassemia identified by a two-stage genome-wide association study. BMC Med Genet. 2010; 11:51. PMID: 20353593.
    View in: PubMed
  156. Panhuysen CI, Kranzler HR, Yu Y, Weiss RD, Brady K, Poling J, Farrer LA, Gelernter J. Confirmation and generalization of an alcohol-dependence locus on chromosome 10q. Neuropsychopharmacology. 2010 May; 35(6):1325-32. PMID: 20147890.
    View in: PubMed
  157. Sweet RA, Bennett DA, Graff-Radford NR, Mayeux R. Assessment and familial aggregation of psychosis in Alzheimer's disease from the National Institute on Aging Late Onset Alzheimer's Disease Family Study. Brain. 2010 Apr; 133(Pt 4):1155-62. PMID: 20147454.
    View in: PubMed
  158. Israeli-Korn SD, Massarwa M, Schechtman E, Strugatsky R, Avni S, Farrer LA, Friedland RP, Inzelberg R. Mild cognitive impairment is associated with mild parkinsonian signs in a door-to-door study. J Alzheimers Dis. 2010; 22(3):1005-13. PMID: 20930290.
    View in: PubMed
  159. Solovieff N, Milton JN, Hartley SW, Sherva R, Sebastiani P, Dworkis DA, Klings ES, Farrer LA, Garrett ME, Ashley-Koch A, Telen MJ, Fucharoen S, Ha SY, Li CK, Chui DH, Baldwin CT, Steinberg MH. Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5' olfactory receptor gene cluster. Blood. 2010 Mar 4; 115(9):1815-22. PMID: 20018918.
    View in: PubMed
  160. Israeli-Korn SD, Masarwa M, Schechtman E, Abuful A, Strugatsky R, Avni S, Farrer LA, Friedland RP, Inzelberg R. Hypertension increases the probability of Alzheimer's disease and of mild cognitive impairment in an Arab community in northern Israel. Neuroepidemiology. 2010; 34(2):99-105. PMID: 20016220.
    View in: PubMed
  161. Kalayasiri R, Gelernter J, Farrer L, Weiss R, Brady K, Gueorguieva R, Kranzler HR, Malison RT. Adolescent cannabis use increases risk for cocaine-induced paranoia. Drug Alcohol Depend. 2010 Mar 1; 107(2-3):196-201. PMID: 19944543.
    View in: PubMed
  162. Xie P, Kranzler HR, Poling J, Stein MB, Anton RF, Brady K, Weiss RD, Farrer L, Gelernter J. Interactive effect of stressful life events and the serotonin transporter 5-HTTLPR genotype on posttraumatic stress disorder diagnosis in 2 independent populations. Arch Gen Psychiatry. 2009 Nov; 66(11):1201-9. PMID: 19884608.
    View in: PubMed
  163. Silveira AC, Morrison MA, Ji F, Xu H, Reinecke JB, Adams SM, Arneberg TM, Janssian M, Lee JE, Yuan Y, Schaumberg DA, Kotoula MG, Tsironi EE, Tsiloulis AN, Chatzoulis DZ, Miller JW, Kim IK, Hageman GS, Farrer LA, Haider NB, DeAngelis MM. Convergence of linkage, gene expression and association data demonstrates the influence of the RAR-related orphan receptor alpha (RORA) gene on neovascular AMD: a systems biology based approach. Vision Res. 2010 Mar 31; 50(7):698-715. PMID: 19786043.
    View in: PubMed
  164. Tang YL, Kranzler HR, Gelernter J, Farrer LA, Pearson D, Cubells JF. Transient cocaine-associated behavioral symptoms rated with a new instrument, the scale for assessment of positive symptoms for cocaine-induced psychosis (SAPS-CIP). Am J Addict. 2009 Sep-Oct; 18(5):339-45. PMID: 19874151.
    View in: PubMed
  165. Douglas KR, Chan G, Gelernter J, Arias AJ, Anton RF, Weiss RD, Brady K, Poling J, Farrer L, Kranzler HR. Adverse childhood events as risk factors for substance dependence: partial mediation by mood and anxiety disorders. Addict Behav. 2010 Jan; 35(1):7-13. PMID: 19720467.
    View in: PubMed
  166. Niciu MJ, Chan G, Gelernter J, Arias AJ, Douglas K, Weiss R, Anton RF, Farrer L, Cubells JF, Kranzler HR. Subtypes of major depression in substance dependence. Addiction. 2009 Oct; 104(10):1700-9. PMID: 19681804.
    View in: PubMed
  167. Green RC, Roberts JS, Cupples LA, Relkin NR, Whitehouse PJ, Brown T, Eckert SL, Butson M, Sadovnick AD, Quaid KA, Chen C, Cook-Deegan R, Farrer LA. Disclosure of APOE genotype for risk of Alzheimer's disease. N Engl J Med. 2009 Jul 16; 361(3):245-54. PMID: 19605829.
    View in: PubMed
  168. Feinn R, Gelernter J, Cubells JF, Farrer L, Kranzler HR. Sources of unreliability in the diagnosis of substance dependence. J Stud Alcohol Drugs. 2009 May; 70(3):475-81. PMID: 19371499.
    View in: PubMed
  169. Cuenco KT, Friedland R, Baldwin CT, Guo J, Vardarajan B, Lunetta KL, Cupples LA, Green RC, DeCarli C, Farrer LA. Association of TTR polymorphisms with hippocampal atrophy in Alzheimer disease families. Neurobiol Aging. 2011 Feb; 32(2):249-56. PMID: 19328595.
    View in: PubMed
  170. Meng YA, Yu Y, Cupples LA, Farrer LA, Lunetta KL. Performance of random forest when SNPs are in linkage disequilibrium. BMC Bioinformatics. 2009; 10:78. PMID: 19265542.
    View in: PubMed
  171. Farrer LA, Kranzler HR, Yu Y, Weiss RD, Brady KT, Anton R, Cubells JF, Gelernter J. Association of variants in MANEA with cocaine-related behaviors. Arch Gen Psychiatry. 2009 Mar; 66(3):267-74. PMID: 19255376.
    View in: PubMed
  172. Zhang H, Kranzler HR, Weiss RD, Luo X, Brady KT, Anton RF, Farrer LA, Gelernter J. Pro-opiomelanocortin gene variation related to alcohol or drug dependence: evidence and replications across family- and population-based studies. Biol Psychiatry. 2009 Jul 15; 66(2):128-36. PMID: 19217079.
    View in: PubMed
  173. Glik A, Masarwa M, Abuful A, Deeb A, Strugatsky R, Farrer LA, Friedland RP, Inzelberg R. Essential tremor might be less frequent than Parkinson's disease in North Israel Arab villages. Mov Disord. 2009 Jan 15; 24(1):119-22. PMID: 18823047.
    View in: PubMed
  174. Perneczky R, Wagenpfeil S, Lunetta KL, Cupples LA, Green RC, DeCarli C, Farrer LA, Kurz A. Education attenuates the effect of medial temporal lobe atrophy on cognitive function in Alzheimer's disease: the MIRAGE study. J Alzheimers Dis. 2009; 17(4):855-62. PMID: 19542606.
    View in: PubMed
  175. Zuo L, Kranzler HR, Luo X, Yang BZ, Weiss R, Brady K, Poling J, Farrer L, Gelernter J. Interaction between two independent CNR1 variants increases risk for cocaine dependence in European Americans: a replication study in family-based sample and population-based sample. Neuropsychopharmacology. 2009 May; 34(6):1504-13. PMID: 19052543.
    View in: PubMed
  176. T Cuenco K, Lunetta KL, Baldwin CT, McKee AC, Guo J, Cupples LA, Green RC, St George-Hyslop PH, Chui H, DeCarli C, Farrer LA. Association of distinct variants in SORL1 with cerebrovascular and neurodegenerative changes related to Alzheimer disease. Arch Neurol. 2008 Dec; 65(12):1640-8. PMID: 19064752.
    View in: PubMed
  177. Gelernter J, Kranzler HR, Panhuysen C, Weiss RD, Brady K, Poling J, Farrer L. Dense genomewide linkage scan for alcohol dependence in African Americans: significant linkage on chromosome 10. Biol Psychiatry. 2009 Jan 15; 65(2):111-5. PMID: 18930185.
    View in: PubMed
  178. Ford JD, Gelernter J, DeVoe JS, Zhang W, Weiss RD, Brady K, Farrer L, Kranzler HR. Association of psychiatric and substance use disorder comorbidity with cocaine dependence severity and treatment utilization in cocaine-dependent individuals. Drug Alcohol Depend. 2009 Jan 1; 99(1-3):193-203. PMID: 18775607.
    View in: PubMed
  179. Sedgewick AE, Timofeev N, Sebastiani P, So JC, Ma ES, Chan LC, Fucharoen G, Fucharoen S, Barbosa CG, Vardarajan BN, Farrer LA, Baldwin CT, Steinberg MH, Chui DH. BCL11A is a major HbF quantitative trait locus in three different populations with beta-hemoglobinopathies. Blood Cells Mol Dis. 2008 Nov-Dec; 41(3):255-8. PMID: 18691915.
    View in: PubMed
  180. Cuenco KT, Green RC, Zhang J, Lunetta K, Erlich PM, Cupples LA, Farrer LA, DeCarli C. Magnetic resonance imaging traits in siblings discordant for Alzheimer disease. J Neuroimaging. 2008 Jul; 18(3):268-75. PMID: 18808654.
    View in: PubMed
  181. Gibney GT, Panhuysen CI, So JC, Ma ES, Ha SY, Li CK, Lee AC, Li CK, Yuen HL, Lau YL, Johnson DM, Farrell JJ, Bisbee AB, Farrer LA, Steinberg MH, Chan LC, Chui DH. Variation and heritability of Hb F and F-cells among beta-thalassemia heterozygotes in Hong Kong. Am J Hematol. 2008 Jun; 83(6):458-64. PMID: 18266208.
    View in: PubMed
  182. Arias AJ, Gelernter J, Chan G, Weiss RD, Brady KT, Farrer L, Kranzler HR. Correlates of co-occurring ADHD in drug-dependent subjects: prevalence and features of substance dependence and psychiatric disorders. Addict Behav. 2008 Sep; 33(9):1199-207. PMID: 18558465.
    View in: PubMed
  183. Yu Y, Kranzler HR, Panhuysen C, Weiss RD, Poling J, Farrer LA, Gelernter J. Substance dependence low-density whole genome association study in two distinct American populations. Hum Genet. 2008 Jun; 123(5):495-506. PMID: 18438686.
    View in: PubMed
  184. Lee JH, Cheng R, Rogaeva E, Meng Y, Stern Y, Santana V, Lantigua R, Medrano M, Jimenez-Velazquez IZ, Farrer LA, St George-Hyslop P, Mayeux R. Further examination of the candidate genes in chromosome 12p13 locus for late-onset Alzheimer disease. Neurogenetics. 2008 May; 9(2):127-38. PMID: 18340469.
    View in: PubMed
  185. Christensen KD, Roberts JS, Royal CD, Fasaye GA, Obisesan T, Cupples LA, Whitehouse PJ, Butson MB, Linnenbringer E, Relkin NR, Farrer L, Cook-Deegan R, Green RC. Incorporating ethnicity into genetic risk assessment for Alzheimer disease: the REVEAL study experience. Genet Med. 2008 Mar; 10(3):207-14. PMID: 18344711.
    View in: PubMed
  186. Meng Y, Lee JH, Cheng R, St George-Hyslop P, Mayeux R, Farrer LA. Association between SORL1 and Alzheimer's disease in a genome-wide study. Neuroreport. 2007 Nov 19; 18(17):1761-4. PMID: 18090307.
    View in: PubMed
  187. Ma Q, Abel K, Sripichai O, Whitacre J, Angkachatchai V, Makarasara W, Winichagoon P, Fucharoen S, Braun A, Farrer LA. Beta-globin gene cluster polymorphisms are strongly associated with severity of HbE/beta(0)-thalassemia. Clin Genet. 2007 Dec; 72(6):497-505. PMID: 17894837.
    View in: PubMed
  188. Tang YL, Kranzler HR, Gelernter J, Farrer LA, Cubells JF. Comorbid psychiatric diagnoses and their association with cocaine-induced psychosis in cocaine-dependent subjects. Am J Addict. 2007 Sep-Oct; 16(5):343-51. PMID: 17882604.
    View in: PubMed
  189. Sebastiani P, Nolan VG, Baldwin CT, Abad-Grau MM, Wang L, Adewoye AH, McMahon LC, Farrer LA, Taylor JG, Kato GJ, Gladwin MT, Steinberg MH. A network model to predict the risk of death in sickle cell disease. Blood. 2007 Oct 1; 110(7):2727-35. PMID: 17600133.
    View in: PubMed
  190. Pierucci-Lagha A, Gelernter J, Chan G, Arias A, Cubells JF, Farrer L, Kranzler HR. Reliability of DSM-IV diagnostic criteria using the semi-structured assessment for drug dependence and alcoholism (SSADDA). Drug Alcohol Depend. 2007 Nov 2; 91(1):85-90. PMID: 17590536.
    View in: PubMed
  191. Kranzler HR, Wilcox M, Weiss RD, Brady K, Hesselbrock V, Rounsaville B, Farrer L, Gelernter J. The validity of cocaine dependence subtypes. Addict Behav. 2008 Jan; 33(1):41-53. PMID: 17582692.
    View in: PubMed
  192. Faison WE, Schultz SK, Aerssens J, Alvidrez J, Anand R, Farrer LA, Jarvik L, Manly J, McRae T, Murphy GM, Olin JT, Regier D, Sano M, Mintzer JE. Potential ethnic modifiers in the assessment and treatment of Alzheimer's disease: challenges for the future. Int Psychogeriatr. 2007 Jun; 19(3):539-58. PMID: 17451614.
    View in: PubMed
  193. Lunetta KL, Erlich PM, Cuenco KT, Cupples LA, Green RC, Farrer LA, Decarli C. Heritability of magnetic resonance imaging (MRI) traits in Alzheimer disease cases and their siblings in the MIRAGE study. Alzheimer Dis Assoc Disord. 2007 Apr-Jun; 21(2):85-91. PMID: 17545732.
    View in: PubMed
  194. Lee JH, Cheng R, Schupf N, Manly J, Lantigua R, Stern Y, Rogaeva E, Wakutani Y, Farrer L, St George-Hyslop P, Mayeux R. The association between genetic variants in SORL1 and Alzheimer disease in an urban, multiethnic, community-based cohort. Arch Neurol. 2007 Apr; 64(4):501-6. PMID: 17420311.
    View in: PubMed
  195. Nolan VG, Ma Q, Cohen HT, Adewoye A, Rybicki AC, Baldwin C, Mahabir RN, Homan EP, Wyszynski DF, Fabry ME, Nagel RL, Farrer LA, Steinberg MH. Estimated glomerular filtration rate in sickle cell anemia is associated with polymorphisms of bone morphogenetic protein receptor 1B. Am J Hematol. 2007 Mar; 82(3):179-84. PMID: 17034027.
    View in: PubMed
  196. Ma Q, Wyszynski DF, Farrell JJ, Kutlar A, Farrer LA, Baldwin CT, Steinberg MH. Fetal hemoglobin in sickle cell anemia: genetic determinants of response to hydroxyurea. Pharmacogenomics J. 2007 Dec; 7(6):386-94. PMID: 17299377.
    View in: PubMed
  197. Rogaeva E, Meng Y, Lee JH, Gu Y, Kawarai T, Zou F, Katayama T, Baldwin CT, Cheng R, Hasegawa H, Chen F, Shibata N, Lunetta KL, Pardossi-Piquard R, Bohm C, Wakutani Y, Cupples LA, Cuenco KT, Green RC, Pinessi L, Rainero I, Sorbi S, Bruni A, Duara R, Friedland RP, Inzelberg R, Hampe W, Bujo H, Song YQ, Andersen OM, Willnow TE, Graff-Radford N, Petersen RC, Dickson D, Der SD, Fraser PE, Schmitt-Ulms G, Younkin S, Mayeux R, Farrer LA, St George-Hyslop P. The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease. Nat Genet. 2007 Feb; 39(2):168-77. PMID: 17220890.
    View in: PubMed
  198. Thal L, Kuller L, Bowman K, Breitner J, Evans D, Farrer L, Frank R, Khachaturian AS, Khachaturian ZS, Kukull W, Nieto J, Petersen R, Sager M, Scherr P, Bain LJ. The Nevada Vital Aging Initiative: a private-public partnership to study early predictors of dementia. Alzheimers Dement. 2007 Jan; 3(1):62-7. PMID: 19595919.
    View in: PubMed
  199. Gelernter J, Yu Y, Weiss R, Brady K, Panhuysen C, Yang BZ, Kranzler HR, Farrer L. Haplotype spanning TTC12 and ANKK1, flanked by the DRD2 and NCAM1 loci, is strongly associated to nicotine dependence in two distinct American populations. Hum Mol Genet. 2006 Dec 15; 15(24):3498-507. PMID: 17085484.
    View in: PubMed
  200. Gelernter J, Panhuysen C, Weiss R, Brady K, Poling J, Krauthammer M, Farrer L, Kranzler HR. Genomewide linkage scan for nicotine dependence: identification of a chromosome 5 risk locus. Biol Psychiatry. 2007 Jan 1; 61(1):119-26. PMID: 17081504.
    View in: PubMed
  201. Akomolafe A, Beiser A, Meigs JB, Au R, Green RC, Farrer LA, Wolf PA, Seshadri S. Diabetes mellitus and risk of developing Alzheimer disease: results from the Framingham Study. Arch Neurol. 2006 Nov; 63(11):1551-5. PMID: 17101823.
    View in: PubMed
  202. Inzelberg R, Schechtman E, Abuful A, Masarwa M, Mazarib A, Strugatsky R, Farrer LA, Green RC, Friedland RP. Education effects on cognitive function in a healthy aged Arab population. Int Psychogeriatr. 2007 Jun; 19(3):593-603. PMID: 17052375.
    View in: PubMed
  203. Terry DF, Wyszynski DF, Nolan VG, Atzmon G, Schoenhofen EA, Pennington JY, Andersen SL, Wilcox MA, Farrer LA, Barzilai N, Baldwin CT, Asea A. Serum heat shock protein 70 level as a biomarker of exceptional longevity. Mech Ageing Dev. 2006 Nov; 127(11):862-8. PMID: 17027907.
    View in: PubMed
  204. Adewoye AH, Nolan VG, Ma Q, Baldwin C, Wyszynski DF, Farrell JJ, Farrer LA, Steinberg MH. Association of polymorphisms of IGF1R and genes in the transforming growth factor- beta /bone morphogenetic protein pathway with bacteremia in sickle cell anemia. Clin Infect Dis. 2006 Sep 1; 43(5):593-8. PMID: 16886151.
    View in: PubMed
  205. Shibata N, Kawarai T, Meng Y, Lee JH, Lee HS, Wakutani Y, Shibata E, Pathan N, Bi A, Sato C, Sorbi S, Bruni AC, Duara R, Mayeux R, Farrer LA, George-Hyslop PS, Rogaeva E. Association studies between the plasmin genes and late-onset Alzheimer's disease. Neurobiol Aging. 2007 Jul; 28(7):1041-3. PMID: 16828203.
    View in: PubMed
  206. Akomolafe A, Lunetta KL, Erlich PM, Cupples LA, Baldwin CT, Huyck M, Green RC, Farrer LA. Genetic association between endothelial nitric oxide synthase and Alzheimer disease. Clin Genet. 2006 Jul; 70(1):49-56. PMID: 16813604.
    View in: PubMed
  207. Yu Y, Panhuysen C, Kranzler HR, Hesselbrock V, Rounsaville B, Weiss R, Brady K, Farrer LA, Gelernter J. Intronic variants in the dopa decarboxylase (DDC) gene are associated with smoking behavior in European-Americans and African-Americans. Hum Mol Genet. 2006 Jul 15; 15(14):2192-9. PMID: 16740595.
    View in: PubMed
  208. Nolan VG, Adewoye A, Baldwin C, Wang L, Ma Q, Wyszynski DF, Farrell JJ, Sebastiani P, Farrer LA, Steinberg MH. Sickle cell leg ulcers: associations with haemolysis and SNPs in Klotho, TEK and genes of the TGF-beta/BMP pathway. Br J Haematol. 2006 Jun; 133(5):570-8. PMID: 16681647.
    View in: PubMed
  209. Green RC, McNagny SE, Jayakumar P, Cupples LA, Benke K, Farrer LA. Statin use and the risk of Alzheimer's disease: the MIRAGE study. Alzheimers Dement. 2006 Apr; 2(2):96-103. PMID: 19595865.
    View in: PubMed
  210. Gelernter J, Panhuysen C, Wilcox M, Hesselbrock V, Rounsaville B, Poling J, Weiss R, Sonne S, Zhao H, Farrer L, Kranzler HR. Genomewide linkage scan for opioid dependence and related traits. Am J Hum Genet. 2006 May; 78(5):759-69. PMID: 16642432.
    View in: PubMed
  211. Meng Y, Baldwin CT, Bowirrat A, Waraska K, Inzelberg R, Friedland RP, Farrer LA. Association of polymorphisms in the Angiotensin-converting enzyme gene with Alzheimer disease in an Israeli Arab community. Am J Hum Genet. 2006 May; 78(5):871-7. PMID: 16642441.
    View in: PubMed
  212. Kalayasiri R, Kranzler HR, Weiss R, Brady K, Gueorguieva R, Panhuysen C, Yang BZ, Farrer L, Gelernter J, Malison RT. Risk factors for cocaine-induced paranoia in cocaine-dependent sibling pairs. Drug Alcohol Depend. 2006 Sep 1; 84(1):77-84. PMID: 16413147.
    View in: PubMed
  213. Tsai DH, Green RC, Benke KS, Silliman RA, Farrer LA. Predictors of subjective memory complaint in cognitively normal relatives of patients with Alzheimer's disease. J Neuropsychiatry Clin Neurosci. 2006; 18(3):384-8. PMID: 16963588.
    View in: PubMed
  214. Burkart KM, Barton SJ, Holloway JW, Yang IA, Cakebread JA, Cruikshank W, Little F, Jin X, Farrer LA, Clough JB, Keith TP, Holgate S, Center DM, O'Connor GT. Association of asthma with a functional promoter polymorphism in the IL16 gene. J Allergy Clin Immunol. 2006 Jan; 117(1):86-91. PMID: 16387589.
    View in: PubMed
  215. Ma Q, Yu Y, Meng Y, Farrell J, Farrer LA, Wilcox MA. Genome-wide linkage analysis for alcohol dependence: a comparison between single-nucleotide polymorphism and microsatellite marker assays. BMC Genet. 2005; 6 Suppl 1:S8. PMID: 16451694.
    View in: PubMed
  216. Meng Y, Ma Q, Yu Y, Farrell J, Farrer LA, Wilcox MA. Multifactor-dimensionality reduction versus family-based association tests in detecting susceptibility loci in discordant sib-pair studies. BMC Genet. 2005; 6 Suppl 1:S146. PMID: 16451606.
    View in: PubMed
  217. Yu Y, Meng Y, Ma Q, Farrell J, Farrer LA, Wilcox MA. Whole-genome variance components linkage analysis using single-nucleotide polymorphisms versus microsatellites on quantitative traits of derived phenotypes from factor analysis of electroencephalogram waves. BMC Genet. 2005; 6 Suppl 1:S15. PMID: 16451610.
    View in: PubMed
  218. Pierucci-Lagha A, Gelernter J, Feinn R, Cubells JF, Pearson D, Pollastri A, Farrer L, Kranzler HR. Diagnostic reliability of the Semi-structured Assessment for Drug Dependence and Alcoholism (SSADDA). Drug Alcohol Depend. 2005 Dec 12; 80(3):303-12. PMID: 15896927.
    View in: PubMed
  219. Erlich PM, Lunetta KL, Cupples LA, Huyck M, Green RC, Baldwin CT, Farrer LA. Polymorphisms in the PON gene cluster are associated with Alzheimer disease. Hum Mol Genet. 2006 Jan 1; 15(1):77-85. PMID: 16319130.
    View in: PubMed
  220. Cubells JF, Feinn R, Pearson D, Burda J, Tang Y, Farrer LA, Gelernter J, Kranzler HR. Rating the severity and character of transient cocaine-induced delusions and hallucinations with a new instrument, the Scale for Assessment of Positive Symptoms for Cocaine-Induced Psychosis (SAPS-CIP). Drug Alcohol Depend. 2005 Oct 1; 80(1):23-33. PMID: 15894433.
    View in: PubMed
  221. Yu Y, Wyszynski DF, Waterworth DM, Wilton SD, Barter PJ, Kesäniemi YA, Mahley RW, McPherson R, Waeber G, Bersot TP, Ma Q, Sharma SS, Montgomery DS, Middleton LT, Sundseth SS, Mooser V, Grundy SM, Farrer LA. Multiple QTLs influencing triglyceride and HDL and total cholesterol levels identified in families with atherogenic dyslipidemia. J Lipid Res. 2005 Oct; 46(10):2202-13. PMID: 16061952.
    View in: PubMed
  222. Yip AG, McKee AC, Green RC, Wells J, Young H, Cupples LA, Farrer LA. APOE, vascular pathology, and the AD brain. Neurology. 2005 Jul 26; 65(2):259-65. PMID: 16043796.
    View in: PubMed
  223. Gelernter J, Panhuysen C, Weiss R, Brady K, Hesselbrock V, Rounsaville B, Poling J, Wilcox M, Farrer L, Kranzler HR. Genomewide linkage scan for cocaine dependence and related traits: significant linkages for a cocaine-related trait and cocaine-induced paranoia. Am J Med Genet B Neuropsychiatr Genet. 2005 Jul 5; 136B(1):45-52. PMID: 15909294.
    View in: PubMed
  224. Nolan VG, Wyszynski DF, Farrer LA, Steinberg MH. Hemolysis-associated priapism in sickle cell disease. Blood. 2005 Nov 1; 106(9):3264-7. PMID: 15985542.
    View in: PubMed
  225. Baldwin C, Nolan VG, Wyszynski DF, Ma QL, Sebastiani P, Embury SH, Bisbee A, Farrell J, Farrer L, Steinberg MH. Association of klotho, bone morphogenic protein 6, and annexin A2 polymorphisms with sickle cell osteonecrosis. Blood. 2005 Jul 1; 106(1):372-5. PMID: 15784727.
    View in: PubMed
  226. Edwards AO, Ritter R, Abel KJ, Manning A, Panhuysen C, Farrer LA. Complement factor H polymorphism and age-related macular degeneration. Science. 2005 Apr 15; 308(5720):421-4. PMID: 15761121.
    View in: PubMed
  227. Bowirrat A, Cui J, Waraska K, Friedland RP, Oscar-Berman M, Farrer LA, Korczyn A, Baldwin CT. Lack of association between angiotensin-converting enzyme and dementia of the Alzheimer's type in an elderly Arab population in Wadi Ara, Israel. Neuropsychiatr Dis Treat. 2005 Mar; 1(1):73-6. PMID: 18568123.
    View in: PubMed
  228. Sato C, Morgan A, Lang AE, Salehi-Rad S, Kawarai T, Meng Y, Ray PN, Farrer LA, St George-Hyslop P, Rogaeva E. Analysis of the glucocerebrosidase gene in Parkinson's disease. Mov Disord. 2005 Mar; 20(3):367-70. PMID: 15517592.
    View in: PubMed
  229. Wyszynski DF, Waterworth DM, Barter PJ, Cohen J, Kesäniemi YA, Mahley RW, McPherson R, Waeber G, Bersot TP, Sharma SS, Nolan V, Middleton LT, Sundseth SS, Farrer LA, Mooser V, Grundy SM. Relation between atherogenic dyslipidemia and the Adult Treatment Program-III definition of metabolic syndrome (Genetic Epidemiology of Metabolic Syndrome Project). Am J Cardiol. 2005 Jan 15; 95(2):194-8. PMID: 15642551.
    View in: PubMed
  230. Yip AG, Green RC, Huyck M, Cupples LA, Farrer LA. Nonsteroidal anti-inflammatory drug use and Alzheimer's disease risk: the MIRAGE Study. BMC Geriatr. 2005; 5:2. PMID: 15647106.
    View in: PubMed
  231. Wyszynski DF, Farrer LA. . Genetics of atherosclerosis in humans. In Loscalzo J (ed). Molecular Mechanisms of Artherosclerosis. Taylor & Francis. London,UK. 2005.
  232. Henderson VW, Benke KS, Green RC, Cupples LA, Farrer LA. Postmenopausal hormone therapy and Alzheimer's disease risk: interaction with age. J Neurol Neurosurg Psychiatry. 2005 Jan; 76(1):103-5. PMID: 15608005.
    View in: PubMed
  233. Zhou XF, Cui J, DeStefano AL, Chazaro I, Farrer LA, Manolis AJ, Gavras H, Baldwin CT. Polymorphisms in the promoter region of catalase gene and essential hypertension. Dis Markers. 2005; 21(1):3-7. PMID: 15735318.
    View in: PubMed
  234. Nolan VG, Baldwin C, Ma Q, Wyszynski DF, Amirault Y, Farrell JJ, Bisbee A, Embury SH, Farrer LA, Steinberg MH. Association of single nucleotide polymorphisms in klotho with priapism in sickle cell anaemia. Br J Haematol. 2005 Jan; 128(2):266-72. PMID: 15638863.
    View in: PubMed
  235. Roberts JS, Barber M, Brown TM, Cupples LA, Farrer LA, LaRusse SA, Post SG, Quaid KA, Ravdin LD, Relkin NR, Sadovnick AD, Whitehouse PJ, Woodard JL, Green RC. Who seeks genetic susceptibility testing for Alzheimer's disease? Findings from a multisite, randomized clinical trial. Genet Med. 2004 Jul-Aug; 6(4):197-203. PMID: 15266207.
    View in: PubMed
  236. Cupples LA, Farrer LA, Sadovnick AD, Relkin N, Whitehouse P, Green RC. Estimating risk curves for first-degree relatives of patients with Alzheimer's disease: the REVEAL study. Genet Med. 2004 Jul-Aug; 6(4):192-6. PMID: 15266206.
    View in: PubMed
  237. Saleh M, Vaillancourt JP, Graham RK, Huyck M, Srinivasula SM, Alnemri ES, Steinberg MH, Nolan V, Baldwin CT, Hotchkiss RS, Buchman TG, Zehnbauer BA, Hayden MR, Farrer LA, Roy S, Nicholson DW. Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms. Nature. 2004 May 6; 429(6987):75-9. PMID: 15129283.
    View in: PubMed
  238. Farrer L. Collection of clinical and epidemiological data for linkage studies. Curr Protoc Hum Genet. 2004 May; Chapter 1:Unit 1.1. PMID: 18428351.
    View in: PubMed
  239. Wyszynski DF, Baldwin CT, Cleves MA, Amirault Y, Nolan VG, Farrell JJ, Bisbee A, Kutlar A, Farrer LA, Steinberg MH. Polymorphisms near a chromosome 6q QTL area are associated with modulation of fetal hemoglobin levels in sickle cell anemia. Cell Mol Biol (Noisy-le-grand). 2004 Feb; 50(1):23-33. PMID: 15040424.
    View in: PubMed
  240. Wyszynski DF, Panhuysen CI, Ma Q, Yip AG, Wilcox M, Erlich P, Farrer LA. Genome-wide screen for heavy alcohol consumption. BMC Genet. 2003; 4 Suppl 1:S106. PMID: 14975174.
    View in: PubMed
  241. Wilcox MA, Wyszynski DF, Panhuysen CI, Ma Q, Yip A, Farrell J, Farrer LA. Empirically derived phenotypic subgroups - qualitative and quantitative trait analyses. BMC Genet. 2003; 4 Suppl 1:S15. PMID: 14975083.
    View in: PubMed
  242. Yip AG, Ma Q, Wilcox M, Panhuysen CI, Farrell J, Farrer LA, Wyszynski DF. Search for genetic factors predisposing to atherogenic dyslipidemia. BMC Genet. 2003; 4 Suppl 1:S100. PMID: 14975168.
    View in: PubMed
  243. Kennedy JL, Farrer LA, Andreasen NC, Mayeux R, St George-Hyslop P. The genetics of adult-onset neuropsychiatric disease: complexities and conundra? Science. 2003 Oct 31; 302(5646):822-6. PMID: 14593167.
    View in: PubMed
  244. Green RC, Cupples LA, Kurz A, Auerbach S, Go R, Sadovnick D, Duara R, Kukull WA, Chui H, Edeki T, Griffith PA, Friedland RP, Bachman D, Farrer L. Depression as a risk factor for Alzheimer disease: the MIRAGE Study. Arch Neurol. 2003 May; 60(5):753-9. PMID: 12756140.
    View in: PubMed
  245. Erlich PM, Cui J, Chazaro I, Farrer LA, Baldwin CT, Gavras H, DeStefano AL. Genetic variants of WNK4 in whites and African Americans with hypertension. Hypertension. 2003 Jun; 41(6):1191-5. PMID: 12719438.
    View in: PubMed
  246. Bachman DL, Green RC, Benke KS, Cupples LA, Farrer LA. Comparison of Alzheimer's disease risk factors in white and African American families. Neurology. 2003 Apr 22; 60(8):1372-4. PMID: 12707449.
    View in: PubMed
  247. Roberts JS, LaRusse SA, Katzen H, Whitehouse PJ, Barber M, Post SG, Relkin N, Quaid K, Pietrzak RH, Cupples LA, Farrer LA, Brown T, Green RC. Reasons for seeking genetic susceptibility testing among first-degree relatives of people with Alzheimer disease. Alzheimer Dis Assoc Disord. 2003 Apr-Jun; 17(2):86-93. PMID: 12794385.
    View in: PubMed
  248. Farrer LA, Bowirrat A, Friedland RP, Waraska K, Korczyn AD, Baldwin CT. Identification of multiple loci for Alzheimer disease in a consanguineous Israeli-Arab community. Hum Mol Genet. 2003 Feb 15; 12(4):415-22. PMID: 12566388.
    View in: PubMed
  249. Farrer LA, Friedland RP, Bowirrat A, Waraska K, Korczyn A, Baldwin CT. Genetic and environmental epidemiology of Alzheimer's disease in arabs residing in Israel. J Mol Neurosci. 2003; 20(3):207-12. PMID: 14500999.
    View in: PubMed
  250. Hipps YG, Roberts JS, Farrer LA, Green RC. Differences between African Americans and Whites in their attitudes toward genetic testing for Alzheimer's disease. Genet Test. 2003; 7(1):39-44. PMID: 12820701.
    View in: PubMed
  251. Bowirrat A, Friedland RP, Farrer L, Baldwin C, Korczyn A. Genetic and environmental risk factors for Alzheimer's disease in Israeli Arabs. J Mol Neurosci. 2002 Aug-Oct; 19(1-2):239-45. PMID: 12212789.
    View in: PubMed
  252. Graff-Radford NR, Green RC, Go RC, Hutton ML, Edeki T, Bachman D, Adamson JL, Griffith P, Willis FB, Williams M, Hipps Y, Haines JL, Cupples LA, Farrer LA. Association between apolipoprotein E genotype and Alzheimer disease in African American subjects. Arch Neurol. 2002 Apr; 59(4):594-600. PMID: 11939894.
    View in: PubMed
  253. Green RC, Cupples LA, Go R, Benke KS, Edeki T, Griffith PA, Williams M, Hipps Y, Graff-Radford N, Bachman D, Farrer LA. Risk of dementia among white and African American relatives of patients with Alzheimer disease. JAMA. 2002 Jan 16; 287(3):329-36. PMID: 11790212.
    View in: PubMed
  254. Friedland RP, Petot GJ, Farrer LA. Alzheimer’s disease and diet. Arab J Psychiatry. 2002; 13:10-17.
  255. Friedland RP, Korczyn A, Farrer LA . Genetic and environmental risk factors for Alzheimer’s disease in Arabs residing in Israel. In: Fillit HM, O’Connell AW (eds). Drug Discovery and Development for Alzheimer’s Disease, 2000. Springer Publishing Co. New York,NY. 2002; 13-16.
  256. Riazanskaia N, Lukiw WJ, Grigorenko A, Korovaitseva G, Dvoryanchikov G, Moliaka Y, Nicolaou M, Farrer L, Bazan NG, Rogaev E. Regulatory region variability in the human presenilin-2 (PSEN2) gene: potential contribution to the gene activity and risk for AD. Mol Psychiatry. 2002; 7(8):891-8. PMID: 12232783.
    View in: PubMed
  257. Nicolaou M, Song YQ, Sato CA, Orlacchio A, Kawarai T, Medeiros H, Liang Y, Sorbi S, Richard E, Rogaev EI, Moliaka Y, Bruni AC, Jorge R, Percy M, Duara R, Farrer LA, St Georg-Hyslop P, Rogaeva EA. Mutations in the open reading frame of the beta-site APP cleaving enzyme (BACE) locus are not a common cause of Alzheimer's disease. Neurogenetics. 2001 Oct; 3(4):203-6. PMID: 11714100.
    View in: PubMed
  258. Lebo RV, Maher T, Farrer L, Fenerci EY, Milunsky JM. Highly polymorphic short tandem repeat analyses clarify complex molecular test results. Diagn Mol Pathol. 2001 Sep; 10(3):179-89. PMID: 11552721.
    View in: PubMed
  259. DeStefano AL, Gavras H, Heard-Costa N, Bursztyn M, Manolis A, Farrer LA, Baldwin CT, Gavras I, Schwartz F. Maternal component in the familial aggregation of hypertension. Clin Genet. 2001 Jul; 60(1):13-21. PMID: 11531965.
    View in: PubMed
  260. Ishii K, Lippa C, Tomiyama T, Miyatake F, Ozawa K, Tamaoka A, Hasegawa T, Fraser PE, Shoji S, Nee LE, Pollen DA, St George-Hyslop PH, Ii K, Ohtake T, Kalaria RN, Rossor MN, Lantos PL, Cairns NJ, Farrer LA, Mori H. Distinguishable effects of presenilin-1 and APP717 mutations on amyloid plaque deposition. Neurobiol Aging. 2001 May-Jun; 22(3):367-76. PMID: 11378241.
    View in: PubMed
  261. Demissie S, Green RC, Mucci L, Tziavas S, Martelli K, Bang K, Coons L, Bourque S, Buchillon D, Johnson K, Smith T, Sharrow N, Lautenschlager N, Friedland R, Cupples LA, Farrer LA. Reliability of information collected by proxy in family studies of Alzheimer's disease. Neuroepidemiology. 2001 May; 20(2):105-11. PMID: 11359077.
    View in: PubMed
  262. Shcherbatykh TV, Kiryanov SA, Korovaitseva GI, Selezneva ND, Voskresenskaya NI, Golimbet VE, Farrer L, Gavrilova SI, Rogaev EI. The angiotensin-converting enzyme gene as a possible risk or protective factor in Alzheimer's disease. Neurosci Behav Physiol. 2001 Mar-Apr; 31(2):179-81. PMID: 11388371.
    View in: PubMed
  263. Farrer LA. Intercontinental epidemiology of Alzheimer disease: a global approach to bad gene hunting. JAMA. 2001 Feb 14; 285(6):796-8. PMID: 11176918.
    View in: PubMed
  264. Myers RH, Cupples LA, Taylor CA, Saint-Hilaire MH, Auerbach SA, Feldman RG, Farrer LA. The genetic component in Parkinson disease is half that of Alzheimer disease. Alzheimers Reports. 2001; 4:9-15.
  265. Yu G, Nishimura M, Arawaka S, Levitan D, Zhang L, Tandon A, Song YQ, Rogaeva E, Chen F, Kawarai T, Supala A, Levesque L, Yu H, Yang DS, Holmes E, Milman P, Liang Y, Zhang DM, Xu DH, Sato C, Rogaev E, Smith M, Janus C, Zhang Y, Aebersold R, Farrer LS, Sorbi S, Bruni A, Fraser P, St George-Hyslop P. Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing. Nature. 2000 Sep 7; 407(6800):48-54. PMID: 10993067.
    View in: PubMed
  266. Guo Z, Cupples LA, Kurz A, Auerbach SH, Volicer L, Chui H, Green RC, Sadovnick AD, Duara R, DeCarli C, Johnson K, Go RC, Growdon JH, Haines JL, Kukull WA, Farrer LA. Head injury and the risk of AD in the MIRAGE study. Neurology. 2000 Mar 28; 54(6):1316-23. PMID: 10746604.
    View in: PubMed
  267. Nicolaou M, DeStefano AL, Gavras I, Cupples LA, Manolis AJ, Baldwin CT, Gavras H, Farrer LA. Genetic predisposition to stroke in relatives of hypertensives. Stroke. 2000 Feb; 31(2):487-92. PMID: 10657427.
    View in: PubMed
  268. Farrer LA, Sherbatich T, Keryanov SA, Korovaitseva GI, Rogaeva EA, Petruk S, Premkumar S, Moliaka Y, Song YQ, Pei Y, Sato C, Selezneva ND, Voskresenskaya S, Golimbet V, Sorbi S, Duara R, Gavrilova S, St George-Hyslop PH, Rogaev EI. Association between angiotensin-converting enzyme and Alzheimer disease. Arch Neurol. 2000 Feb; 57(2):210-4. PMID: 10681079.
    View in: PubMed
  269. St. George-Hyslop PH, Farrer LA, Goedert M . Alzheimer disease and the fronto-temporal dementias: diseases with cerebral deposition of fibrillar proteins. In Molecular and Metabolic Basis of Inherited Disease, 8th edition. chapter 234. McGraw-Hill, Inc. 2000; 4:5785-5899.
  270. Farrer LA. Familial risk for Alzheimer disease in ethnic minorities: nondiscriminating genes. Arch Neurol. 2000 Jan; 57(1):28-9. PMID: 10634429.
    View in: PubMed
  271. Cupples LA, Weinberg J, Beiser A, Auerbach SH, Volicer L, Cipolloni PB, Wells J, Growdon JH, D’Agostino R, Wolf PA, Farrer LA. Effects of smoking, alcohol and APOE genotype on Alzheimer disease: The MIRAGE Study. Alzheimers Reports. 2000; 3:105-113.
  272. Small GW, Scott WK, Komo S, Yamaoka LH, Farrer LA, Auerbach SH, Saunders AM, Roses AD, Haines JL, Pericak-Vance MA. No association between the HLA-A2 allele and Alzheimer disease. Neurogenetics. 1999 Sep; 2(3):177-82. PMID: 10541592.
    View in: PubMed
  273. Baldwin CT, Schwartz F, Baima J, Burzstyn M, DeStefano AL, Gavras I, Handy DE, Joost O, Martel T, Manolis A, Nicolaou M, Bresnahan M, Farrer L, Gavras H. Identification of a polymorphic glutamic acid stretch in the alpha2B-adrenergic receptor and lack of linkage with essential hypertension. Am J Hypertens. 1999 Sep; 12(9 Pt 1):853-7. PMID: 10509541.
    View in: PubMed
  274. Korovaitseva GI, Premkumar S, Grigorenko A, Molyaka Y, Galimbet V, Selezneva N, Gavrilova SI, Farrer LA, Rogaev EI. Alpha-2 macroglobulin gene in early- and late-onset Alzheimer disease. Neurosci Lett. 1999 Aug 20; 271(2):129-31. PMID: 10477119.
    View in: PubMed
  275. Baima J, Nicolaou M, Schwartz F, DeStefano AL, Manolis A, Gavras I, Laffer C, Elijovich F, Farrer L, Baldwin CT, Gavras H. Evidence for linkage between essential hypertension and a putative locus on human chromosome 17. Hypertension. 1999 Jul; 34(1):4-7. PMID: 10406815.
    View in: PubMed
  276. Rogaeva EA, Premkumar S, Grubber J, Serneels L, Scott WK, Kawarai T, Song Y, Hill DL, Abou-Donia SM, Martin ER, Vance JJ, Yu G, Orlacchio A, Pei Y, Nishimura M, Supala A, Roberge B, Saunders AM, Roses AD, Schmechel D, Crane-Gatherum A, Sorbi S, Bruni A, Small GW, Conneally PM, Haines JL, Van Leuven F, St George-Hyslop PH, Farrer LA, Pericak-Vance MA. An alpha-2-macroglobulin insertion-deletion polymorphism in Alzheimer disease. Nat Genet. 1999 May; 22(1):19-22. PMID: 10319855.
    View in: PubMed
  277. Bailey JM, Pillard RC, Dawood K, Miller MB, Farrer LA, Trivedi S, Murphy RL. A family history study of male sexual orientation using three independent samples. Behav Genet. 1999 Mar; 29(2):79-86. PMID: 10405456.
    View in: PubMed
  278. Farrer LA. Locating genetic modifiers for inherited neurodegenerative diseases. In Peters A, Morrison JH, (eds). Cerebral Cortex, volume 14. Neurodegenerative and Age-Related Changes in Structure and Function of the Cerebral Cortex. Chapter 12. Plenum Publishing Co. New York,NY. 1999; 14:433-459.
  279. Nicolaou M, Premkumar S, DeStefano AL, Farrer LA, Cupples LA. Power of concordant versus discordant sib pairs at different penetrance levels. Genet Epidemiol. 1999; 17 Suppl 1:S679-84. PMID: 10597513.
    View in: PubMed
  280. Wilk JB, Premkumar S, Nicolaou M, Myers RH, Maher NE, Harmon MD, Farrer LA, DeStefano AL, Cupples LA, Couropmitree NN. Stratification techniques to explore genotype environment interactions. Genet Epidemiol. 1999; 17 Suppl 1:S761-6. PMID: 10597527.
    View in: PubMed
  281. Farrer LA, Abraham CR, Haines JL, Rogaeva EA, Song Y, McGraw WT, Brindle N, Premkumar S, Scott WK, Yamaoka LH, Saunders AM, Roses AD, Auerbach SA, Sorbi S, Duara R, Pericak-Vance MA, St George-Hyslop PH. Association between bleomycin hydrolase and Alzheimer's disease in caucasians. Ann Neurol. 1998 Nov; 44(5):808-11. PMID: 9818937.
    View in: PubMed
  282. DeStefano AL, Baldwin CT, Burzstyn M, Gavras I, Handy DE, Joost O, Martel T, Nicolaou M, Schwartz F, Streeten DH, Farrer LA, Gavras H. Autosomal dominant orthostatic hypotensive disorder maps to chromosome 18q. Am J Hum Genet. 1998 Nov; 63(5):1425-30. PMID: 9792870.
    View in: PubMed
  283. Friedland RP, Farrer LA, Cupples LA, Debanne SM, Lerner AJ. Smoking and risk of Alzheimer's disease. MIRAGE Study Group. Lancet. 1998 Sep 5; 352(9130):819. PMID: 9737315.
    View in: PubMed
  284. Rogaeva E, Premkumar S, Song Y, Sorbi S, Brindle N, Paterson A, Duara R, Levesque G, Yu G, Nishimura M, Ikeda M, O'Toole C, Kawarai T, Jorge R, Vilarino D, Bruni AC, Farrer LA, St George-Hyslop PH. Evidence for an Alzheimer disease susceptibility locus on chromosome 12 and for further locus heterogeneity. JAMA. 1998 Aug 19; 280(7):614-8. PMID: 9718052.
    View in: PubMed
  285. Song YQ, Rogaeva E, Premkumar S, Brindle N, Kawarai T, Orlacchio A, Yu G, Levesque G, Nishimura M, Ikeda M, Pei Y, O'Toole C, Duara R, Barker W, Sorbi S, Freedman M, Farrer L, St George-Hyslop P. Absence of association between Alzheimer disease and the -491 regulatory region polymorphism of APOE. Neurosci Lett. 1998 Jul 10; 250(3):189-92. PMID: 9708864.
    View in: PubMed
  286. Brindle N, Song Y, Rogaeva E, Premkumar S, Levesque G, Yu G, Ikeda M, Nishimura M, Paterson A, Sorbi S, Duara R, Farrer L, St George-Hyslop P. Analysis of the butyrylcholinesterase gene and nearby chromosome 3 markers in Alzheimer disease. Hum Mol Genet. 1998 May; 7(5):933-5. PMID: 9536099.
    View in: PubMed
  287. DeStefano AL, Cupples LA, Arnos KS, Asher JH, Baldwin CT, Blanton S, Carey ML, da Silva EO, Friedman TB, Greenberg J, Lalwani AK, Milunsky A, Nance WE, Pandya A, Ramesar RS, Read AP, Tassabejhi M, Wilcox ER, Farrer LA. Correlation between Waardenburg syndrome phenotype and genotype in a population of individuals with identified PAX3 mutations. Hum Genet. 1998 May; 102(5):499-506. PMID: 9654197.
    View in: PubMed
  288. Tamaoka A, Fraser PE, Ishii K, Sahara N, Ozawa K, Ikeda M, Saunders AM, Komatsuzaki Y, Sherrington R, Levesque G, Yu G, Rogaeva E, Shoji S, Nee LE, Pollen DA, Hendriks L, Martin JJ, Van Broeckhoven C, Roses AD, Farrer LA, St George-Hyslop PH, Mori H. Amyloid-beta-protein isoforms in brain of subjects with PS1-linked, beta APP-linked and sporadic Alzheimer disease. Brain Res Mol Brain Res. 1998 May; 56(1-2):178-85. PMID: 9602117.
    View in: PubMed
  289. Scott WK, Yamaoka LH, Bass MP, Gaskell PC, Conneally PM, Small GW, Farrer LA, Auerbach SA, Saunders AM, Roses AD, Haines JL, Pericak-Vance MA. No genetic association between the LRP receptor and sporadic or late-onset familial Alzheimer disease. Neurogenetics. 1998 Mar; 1(3):179-83. PMID: 10737120.
    View in: PubMed
  290. Farrer LA, Cupples LA . Determining the genetic component of a disease. In: Haines JL, Pericak-Vance MA (eds). Approaches to Gene Mapping Studies in Complex Human Diseases. Chapter 5. John Wiley & Sons. New York,NY. 1998; 93-130.
  291. Kalinsky H, Funes A, Zeldin A, Pel-Or Y, Korostishevsky M, Gershoni-Baruch R, Farrer LA, Bonne-Tamir B. Novel ATP7B mutations causing Wilson disease in several Israeli ethnic groups. Hum Mutat. 1998; 11(2):145-51. PMID: 9482578.
    View in: PubMed
  292. Farrer LA, Cupples LA, Haines JL, Hyman B, Kukull WA, Mayeux R, Myers RH, Pericak-Vance MA, Risch N, van Duijn CM. Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium. JAMA. 1997 Oct 22-29; 278(16):1349-56. PMID: 9343467.
    View in: PubMed
  293. Korovaitseva GI, Bukina A, Farrer LA, Rogaev EI. Presenilin polymorphisms in Alzheimer's disease. Lancet. 1997 Sep 27; 350(9082):959. PMID: 9314893.
    View in: PubMed
  294. Scott WK, Saunders AM, Gaskell PC, Locke PA, Growdon JH, Farrer LA, Auerbach SA, Roses AD, Haines JL, Pericak-Vance MA. Apolipoprotein E epsilon2 does not increase risk of early-onset sporadic Alzheimer's disease. Ann Neurol. 1997 Sep; 42(3):376-8. PMID: 9307262.
    View in: PubMed
  295. Post SG, Whitehouse PJ, Binstock RH, Bird TD, Eckert SK, Farrer LA, Fleck LM, Gaines AD, Juengst ET, Karlinsky H, Miles S, Murray TH, Quaid KA, Relkin NR, Roses AD, St George-Hyslop PH, Sachs GA, Steinbock B, Truschke EF, Zinn AB. The clinical introduction of genetic testing for Alzheimer disease. An ethical perspective. JAMA. 1997 Mar 12; 277(10):832-6. PMID: 9052715.
    View in: PubMed
  296. Farrer LA. Genetics and the dementia patient. Neurologist. 1997; 3:13-30.
  297. Farrer LA, Cupples LA, Kukull WA, Volicer L, Wells JM, Kurz A, Green RC, Chui H, Duara R, Auerbach SA, Larson E, Lautenschlager N, Wolf PA, D’Agostino R, Ordovas J, Schaefer E, Growdon JH, Haines JL. Risk of Alzheimer disease is associated with parental age among apolipoprotein E e4 heterozygotes. Alzheimer’s Research. 1997; 3:83-91.
  298. Scott WK, Yamaoka LH, Locke PA, Rosi BL, Gaskell PC, Saunders AM, Conneally PM, Small GW, Farrer LA, Growdon JH, Roses AD, Pericak-Vance MA, Haines JL. No association or linkage between an intronic polymorphism of presenilin-1 and sporadic or late-onset familial Alzheimer disease. Genet Epidemiol. 1997; 14(3):307-15. PMID: 9181359.
    View in: PubMed
  299. DeStefano AL, Cupples LA, Myers RH, Farrer LA. Detecting linkage for a complex disease using simulated extended pedigrees. Genet Epidemiol. 1997; 14(6):981-6. PMID: 9433611.
    View in: PubMed
  300. Haines JL, Pritchard ML, Saunders AM, Schildkraut JM, Growdon JH, Gaskell PC, Farrer LA, Auerbach SA, Gusella JF, Locke PA, Rosi BL, Yamaoka L, Small GW, Conneally PM, Roses AD, Pericak-Vance M. No association between alpha 1-antichymotrypsin and familial Alzheimer's disease. Ann N Y Acad Sci. 1996 Dec 16; 802:35-41. PMID: 8993482.
    View in: PubMed
  301. Gaspar C, Lopes-Cendes I, DeStefano AL, Maciel P, Silveira I, Coutinho P, MacLeod P, Sequeiros J, Farrer LA, Rouleau GA. Linkage disequilibrium analysis in Machado-Joseph disease patients of different ethnic origins. Hum Genet. 1996 Nov; 98(5):620-4. PMID: 8882886.
    View in: PubMed
  302. Rao VS, Cupples A, van Duijn CM, Kurz A, Green RC, Chui H, Duara R, Auerbach SA, Volicer L, Wells J, van Broeckhoven C, Growdon JH, Haines JL, Farrer LA. Evidence for major gene inheritance of Alzheimer disease in families of patients with and without apolipoprotein E epsilon 4. Am J Hum Genet. 1996 Sep; 59(3):664-75. PMID: 8751868.
    View in: PubMed
  303. DeStefano AL, Cupples LA, Maciel P, Gaspar C, Radvany J, Dawson DM, Sudarsky L, Corwin L, Coutinho P, MacLeod P, et al. A familial factor independent of CAG repeat length influences age at onset of Machado-Joseph disease. Am J Hum Genet. 1996 Jul; 59(1):119-27. PMID: 8659514.
    View in: PubMed
  304. Lautenschlager NT, Milunsky A, DeStefano A, Farrer L, Baldwin CT. A novel mutation in the MITF gene causes Waardenburg syndrome type 2. Genet Anal. 1996 Jul; 13(2):43-4. PMID: 8880147.
    View in: PubMed
  305. Bonné-Tamir B, DeStefano AL, Briggs CE, Adair R, Franklyn B, Weiss S, Korostishevsky M, Frydman M, Baldwin CT, Farrer LA. Linkage of congenital recessive deafness (gene DFNB10) to chromosome 21q22.3. Am J Hum Genet. 1996 Jun; 58(6):1254-9. PMID: 8651303.
    View in: PubMed
  306. Rogaev EI, Rogaeva EA, Korovaitseva GI, Farrer LA, Petrin AN, Keryanov SA, Turaeva S, Chumakov I, St George-Hyslop P, Ginter EK. Linkage of polymorphic congenital cataract to the gamma-crystallin gene locus on human chromosome 2q33-35. Hum Mol Genet. 1996 May; 5(5):699-703. PMID: 8733140.
    View in: PubMed
  307. Haines JL, Pritchard ML, Saunders AM, Schildkraut JM, Growdon JH, Gaskell PC, Farrer LA, Auerbach SA, Gusella JF, Locke PA, Rosi BL, Yamaoka L, Small GW, Conneally PM, Roses AD, Pericak-Vance MA. No genetic effect of alpha1-antichymotrypsin in Alzheimer disease. Genomics. 1996 Apr 1; 33(1):53-6. PMID: 8617509.
    View in: PubMed
  308. Lautenschlager NT, Cupples LA, Rao VS, Auerbach SA, Becker R, Burke J, Chui H, Duara R, Foley EJ, Glatt SL, Green RC, Jones R, Karlinsky H, Kukull WA, Kurz A, Larson EB, Martelli K, Sadovnick AD, Volicer L, Waring SC, Growdon JH, Farrer LA. Risk of dementia among relatives of Alzheimer's disease patients in the MIRAGE study: What is in store for the oldest old? Neurology. 1996 Mar; 46(3):641-50. PMID: 8618660.
    View in: PubMed
  309. National Institute on Aging/Alzheimer’s Association Working Group (Tanzi R, Breitner J, Farrer L, Gandy S, Haines J, Hyman B, Mullan M, Poirier J, Strittmatter W, Folstein M, Farlow M, Mayeux R, Petersen R, Roses A, Schenk D, Small G, van Gool W, Cook-Degan R, Fleck L, Kapp M, Karlinsky H, Pericak-Vance M, Post S, Wolpert C, Berg L, Blass J, Fletcher J, Hegele R, Khachaturian Z, Selkoe D, Thal L, Whitehouse P . Apolipoprotein E genotyping in Alzheimer’s disease. Lancet. 1996; 347:1091-1095.
  310. Farrer LA, Abraham CR, Volicer L, Foley EJ, Kowall NW, McKee AC, Wells JM. Allele epsilon 4 of apolipoprotein E shows a dose effect on age at onset of Pick disease. Exp Neurol. 1995 Dec; 136(2):162-70. PMID: 7498406.
    View in: PubMed
  311. Farrer LA, Cupples LA, van Duijn CM, Kurz A, Zimmer R, Müller U, Green RC, Clarke V, Shoffner J, Wallace DC, et al. Apolipoprotein E genotype in patients with Alzheimer's disease: implications for the risk of dementia among relatives. Ann Neurol. 1995 Nov; 38(5):797-808. PMID: 7486872.
    View in: PubMed
  312. Statement on use of apolipoprotein E testing for Alzheimer disease. American College of Medical Genetics/American Society of Human Genetics Working Group on ApoE and Alzheimer disease. JAMA. 1995 Nov 22-29; 274(20):1627-9. PMID: 7474250.
    View in: PubMed
  313. DeStefano AL, Farrer LA, Maciel P, Gaspar C, Rouleau GA, Coutinho P, Sequeiros J. Gender equality in Machado-Joseph disease. Nat Genet. 1995 Oct; 11(2):118-9. PMID: 7550334.
    View in: PubMed
  314. Baldwin CT, Weiss S, Farrer LA, De Stefano AL, Adair R, Franklyn B, Kidd KK, Korostishevsky M, Bonné-Tamir B. Linkage of congenital, recessive deafness (DFNB4) to chromosome 7q31 and evidence for genetic heterogeneity in the Middle Eastern Druze population. Hum Mol Genet. 1995 Sep; 4(9):1637-42. PMID: 8541853.
    View in: PubMed
  315. Farrer LA, Cupples LA, van Duijn CM, Connor-Lacke L, Kiely DK, Growdon JH. Rate of progression of Alzheimer's disease is associated with genetic risk. Arch Neurol. 1995 Sep; 52(9):918-23. PMID: 7661731.
    View in: PubMed
  316. Van Camp G, Van Thienen MN, Handig I, Van Roy B, Rao VS, Milunsky A, Read AP, Baldwin CT, Farrer LA, Bonduelle M, et al. Chromosome 13q deletion with Waardenburg syndrome: further evidence for a gene involved in neural crest function on 13q. J Med Genet. 1995 Jul; 32(7):531-6. PMID: 7562965.
    View in: PubMed
  317. Maciel P, Gaspar C, DeStefano AL, Silveira I, Coutinho P, Radvany J, Dawson DM, Sudarsky L, Guimarães J, Loureiro JE, et al. Correlation between CAG repeat length and clinical features in Machado-Joseph disease. Am J Hum Genet. 1995 Jul; 57(1):54-61. PMID: 7611296.
    View in: PubMed
  318. Baldwin CT, Farrer LA, Adair R, Dharmavaram R, Jimenez S, Anderson L. Linkage of early-onset osteoarthritis and chondrocalcinosis to human chromosome 8q. Am J Hum Genet. 1995 Mar; 56(3):692-7. PMID: 7887424.
    View in: PubMed
  319. Twist EC, Casaubon LK, Ruttledge MH, Rao VS, Macleod PM, Radvany J, Zhao Z, Rosenberg RN, Farrer LA, Rouleau GA. Machado Joseph disease maps to the same region of chromosome 14 as the spinocerebellar ataxia type 3 locus. J Med Genet. 1995 Jan; 32(1):25-31. PMID: 7897622.
    View in: PubMed
  320. Rao VS, Cupples LA, Auerbach SA, Becker R, Burke J, Chui H, Duara R, Foley EJ, Glatt S, Green RC, Growdon JH, Karlinsky H, Kukull W, Kurz A, Jones R, Larson EB, Martelli K, Sadovnick AD, Smith GE, Volicer L, Farrer LA . Age at onset of Alzheimer Disease is influenced by multiple genetic and non-genetic factors: The MIRAGE Study. Alzheimer's Research. 1995; 1:159-168.
  321. Rao VS, van Duijn CM, Connor-Lacke L, Cupples LA, Growdon JH, Farrer LA. Multiple etiologies for Alzheimer disease are revealed by segregation analysis. Am J Hum Genet. 1994 Nov; 55(5):991-1000. PMID: 7977363.
    View in: PubMed
  322. Farrer LA, Arnos KS, Asher JH, Baldwin CT, Diehl SR, Friedman TB, Greenberg J, Grundfast KM, Hoth C, Lalwani AK, et al. Locus heterogeneity for Waardenburg syndrome is predictive of clinical subtypes. Am J Hum Genet. 1994 Oct; 55(4):728-37. PMID: 7942851.
    View in: PubMed
  323. van Duijn CM, Hendriks L, Farrer LA, Backhovens H, Cruts M, Wehnert A, Hofman A, Van Broeckhoven C. A population-based study of familial Alzheimer disease: linkage to chromosomes 14, 19, and 21. Am J Hum Genet. 1994 Oct; 55(4):714-27. PMID: 7942850.
    View in: PubMed
  324. Lautenschlager N, Foley EJ, Haupt M, Zimmer R, Farrer LA, Kurz A. [A systematic genetic-epidemiologic family study of patients with Alzheimer disease--experience with the MIRAGE study in Germany]. Z Gerontol. 1994 Sep-Oct; 27(5):341-5. PMID: 7810203.
    View in: PubMed
  325. Farrer LA, Cupples LA, Blackburn S, Kiely DK, Auerbach S, Growdon JH, Connor-Lacke L, Karlinsky H, Thibert A, Burke JR, et al. Interrater agreement for diagnosis of Alzheimer's disease: the MIRAGE study. Neurology. 1994 Apr; 44(4):652-6. PMID: 8164819.
    View in: PubMed
  326. Rogaev EI, Rogaeva EA, Ginter EK, Korovaitseva GI, Farrer L, Shlenskii AB, Prytkov AN, St George-Hyslop P, Mordovtsev VN. [Mapping the gene for palmoplantar hyperkeratosis (thylosis) to chromosome 17 in the 17q12-q24 region]. Genetika. 1994 Mar; 30(3):326-9. PMID: 7514555.
    View in: PubMed
  327. Twist EC, Farrer LA, Macleod PM, Radvany J, Chamberlain S, Rosenberg RN, Rouleau GA. Machado Joseph disease is not an allele of the spinocerebellar ataxia 2 locus. Hum Genet. 1994 Mar; 93(3):335-8. PMID: 8125487.
    View in: PubMed
  328. Farrer LA, Cupples LA. Estimating the probability for major gene Alzheimer disease. Am J Hum Genet. 1994 Feb; 54(2):374-83. PMID: 8304352.
    View in: PubMed
  329. Bowcock AM, Tomfohrde J, Weissenbach J, Bonne-Tamir B, St George-Hyslop P, Giagheddu M, Cavalli-Sforza LL, Farrer LA. Refining the position of Wilson disease by linkage disequilibrium with polymorphic microsatellites. Am J Hum Genet. 1994 Jan; 54(1):79-87. PMID: 8279473.
    View in: PubMed
  330. Farrer LA . Collection of clinical and epidemiological information. In: Current Protocols in Human Genetics (Chapter 1: Genetic Mapping). Greene Publishing Assoc. New York,NY. 1994; 136-155.
  331. Farrer LA. . Neurogenetics of Aging. In: Albert ML, Knoefel JE (eds). Clinical Neurology of Aging, 2nd edition. Oxford University Press. New York,NY. 1994; 136-155.
  332. White A, Tomfohrde J, Stewart E, Barnes R, Le Paslier D, Weissenbach J, Cavalli-Sforza L, Farrer L, Bowcock A. A 4.5-megabase yeast artificial chromosome contig from human chromosome 13q14.3 ordering 9 polymorphic microsatellites (22 sequence-tagged sites) tightly linked to the Wilson disease locus. Proc Natl Acad Sci U S A. 1993 Nov 1; 90(21):10105-9. PMID: 8234264.
    View in: PubMed
  333. Stewart EA, White A, Tomfohrde J, Osborne-Lawrence S, Prestridge L, Bonne-Tamir B, Scheinberg IH, St George-Hyslop P, Giagheddu M, Kim JW, et al. Polymorphic microsatellites and Wilson disease (WD). Am J Hum Genet. 1993 Oct; 53(4):864-73. PMID: 8213814.
    View in: PubMed
  334. Rogaev EI, Rogaeva EA, Ginter EK, Korovaitseva GI, Farrer LA, Shlensky AB, Pritkov AN, Mordovtsev VN, St George-Hyslop PH. Identification of the genetic locus for keratosis palmaris et plantaris on chromosome 17 near the RARA and keratin type I genes. Nat Genet. 1993 Oct; 5(2):158-62. PMID: 7504553.
    View in: PubMed
  335. Borgaonkar DS, Schmidt LC, Martin SE, Kanzer MD, Edelsohn L, Growdon J, Farrer LA. Linkage of late-onset Alzheimer's disease with apolipoprotein E type 4 on chromosome 19. Lancet. 1993 Sep 4; 342(8871):625. PMID: 8102761.
    View in: PubMed
  336. van Duijn CM, Farrer LA, Cupples LA, Hofman A. Genetic transmission of Alzheimer's disease among families in a Dutch population based study. J Med Genet. 1993 Aug; 30(8):640-6. PMID: 8411049.
    View in: PubMed
  337. Farrer LA, Cupples LA, Wiater P, Conneally PM, Gusella JF, Myers RH. The normal Huntington disease (HD) allele, or a closely linked gene, influences age at onset of HD. Am J Hum Genet. 1993 Jul; 53(1):125-30. PMID: 8317477.
    View in: PubMed
  338. Milunsky A, Huang X, Amos JA, Herskowitz J, Farrer LA, Wyandt HE. 46,XY/47,XYY male with the fragile X syndrome: cytogenetic and molecular studies. Am J Med Genet. 1993 Mar 1; 45(5):589-93. PMID: 8096117.
    View in: PubMed
  339. Farrer LA . Book review: Hannah's Heirs: The Quest for the Genetic Origins of Alzheimer's Disease. New Engl J Med. 1993; 329:1972-1973.
  340. Farrer LA, Stice L. Susceptibility genes for familial Alzheimer's disease on chromosomes 19 and 21: a reality check. Genet Epidemiol. 1993; 10(6):425-30. PMID: 8314038.
    View in: PubMed
  341. St George-Hyslop P, Haines J, Rogaev E, Mortilla M, Vaula G, Pericak-Vance M, Foncin JF, Montesi M, Bruni A, Sorbi S, Rainero I, Pinessi L, Pollen D, Polinsky R, Nee L, Kennedy J, Macciardi F, Rogaeva E, Liang Y, Alexandrova N, Lukiw W, Schlumpf K, Tanzi R, Tsuda T, Farrer L, Cantu JM, Duara R, Amaducci L, Bergamini L, Gusella J, Roses A, Crapper McLachlan D, et al. Genetic evidence for a novel familial Alzheimer's disease locus on chromosome 14. Nat Genet. 1992 Dec; 2(4):330-4. PMID: 1303289.
    View in: PubMed
  342. Karlinsky H, Berg JM, Lennox A, Ray PN, St George-Hyslop P, Farrer LA, Percy ME, Andrews DF, Atack EA. Monozygotic twins concordant for late-onset probable Alzheimer disease with suspected Alzheimer disease in four sibs. Am J Med Genet. 1992 Nov 15; 44(5):591-7. PMID: 1481815.
    View in: PubMed
  343. Farrer LA. Gene localization by linkage analysis. Otolaryngol Clin North Am. 1992 Oct; 25(5):907-22. PMID: 1408195.
    View in: PubMed
  344. Carson WJ, Radvany J, Farrer LA, Vincent D, Rosenberg RN, MacLeod PM, Rouleau GA. The Machado-Joseph disease locus is different from the spinocerebellar ataxia locus (SCA1). Genomics. 1992 Jul; 13(3):852-5. PMID: 1639414.
    View in: PubMed
  345. Farrer LA, Grundfast KM, Amos J, Arnos KS, Asher JH, Beighton P, Diehl SR, Fex J, Foy C, Friedman TB, et al. Waardenburg syndrome (WS) type I is caused by defects at multiple loci, one of which is near ALPP on chromosome 2: first report of the WS consortium. Am J Hum Genet. 1992 May; 50(5):902-13. PMID: 1349198.
    View in: PubMed
  346. Krawczak M, Bockel B. Does the omission of missing information bias the estimates of age-at-onset distributions? Am J Hum Genet. 1992 Mar; 50(3):652-4. PMID: 1531731.
    View in: PubMed
  347. Ridley RM, Farrer LA, Frith CD, Conneally PM. A test of the hypothesis that age at onset in Huntington disease is controlled by an X-linked recessive modifier. Am J Hum Genet. 1992 Mar; 50(3):536-43. PMID: 1531730.
    View in: PubMed
  348. Albritton LM, Bowcock AM, Eddy RL, Morton CC, Tseng L, Farrer LA, Cavalli-Sforza LL, Shows TB, Cunningham JM. The human cationic amino acid transporter (ATRC1): physical and genetic mapping to 13q12-q14. Genomics. 1992 Mar; 12(3):430-4. PMID: 1348489.
    View in: PubMed
  349. Tzourio C, Bonaiti C, Clerget-Darpoux F, Alperovitch A. Segregation analysis in Alzheimer disease: no evidence for a major gene. Am J Hum Genet. 1992 Mar; 50(3):645-8. PMID: 1539601.
    View in: PubMed
  350. Farrer LA, Cupples LA, Kiely DK, Conneally PM, Myers RH. Inverse relationship between age at onset of Huntington disease and paternal age suggests involvement of genetic imprinting. Am J Hum Genet. 1992 Mar; 50(3):528-35. PMID: 1531729.
    View in: PubMed
  351. Farrer LA, Myers RH, Cupples LA. Segregation analysis of total nevus density and estimation of lifetime risk and average onset age of melanoma. Cytogenet Cell Genet. 1992; 59(2-3):197-9. PMID: 1737499.
    View in: PubMed
  352. Farrer LA . Book review: Alzheimer's Disease and the Environment (Royal Society of Medicine Services, Round Table Series, No. 26). Neurology. 1992; 42:1648.
  353. Bowcock AM, Farrer LA, Hebert JM, Bale AE, Cavalli-Sforza L. A contiguous linkage map of chromosome 13q with 39 distinct loci separated on average by 5.1 centimorgans. Genomics. 1991 Nov; 11(3):517-29. PMID: 1685473.
    View in: PubMed
  354. Cupples LA, Risch N, Farrer LA, Myers RH. Estimation of morbid risk and age at onset with missing information. Am J Hum Genet. 1991 Jul; 49(1):76-87. PMID: 1829582.
    View in: PubMed
  355. Farrer LA, Bowcock AM, Hebert JM, Bonné-Tamir B, Sternlieb I, Giagheddu M, St George-Hyslop P, Frydman M, Lössner J, Demelia L, et al. Predictive testing for Wilson's disease using tightly linked and flanking DNA markers. Neurology. 1991 Jul; 41(7):992-9. PMID: 2067662.
    View in: PubMed
  356. Farrer LA, Myers RH, Connor L, Cupples LA, Growdon JH. Segregation analysis reveals evidence of a major gene for Alzheimer disease. Am J Hum Genet. 1991 Jun; 48(6):1026-33. PMID: 2035523.
    View in: PubMed
  357. Farrer LA, Cupples LA, Connor L, Wolf PA, Growdon JH. Association of decreased paternal age and late-onset Alzheimer's disease. An example of genetic imprinting? Arch Neurol. 1991 Jun; 48(6):599-604. PMID: 2039382.
    View in: PubMed
  358. Ridley RM, Frith CD, Farrer LA, Conneally PM. Patterns of inheritance of the symptoms of Huntington's disease suggestive of an effect of genomic imprinting. J Med Genet. 1991 Apr; 28(4):224-31. PMID: 1830339.
    View in: PubMed
  359. St. George-Hyslop PH, Haines JL, Polinsky RJ, Farrer LA, Myers RH, Gusella JF. Molecular genetics of familial Alzheimer's disease and its implications. In: Berg JM, Karlinsky H, Lowy FH (eds). Alzheimer's Disease Research: Ethical and Legal Issues. Thomson Professional Publishing. Canada. 1991; 141-149.
  360. Van Duijn CM, Farrer LA, Cupples LA, Hofman A . Risk of dementia in first degree relatives of patients with Alzheimer's disease. In: Iqbal K, McLachlan DRC, Winblad B, Wisniewski HM (eds). Alzheimer's Disease: Basic Mechanisms, Diagnosis and Therapeutic Strategies. John Wiley and Sons. New York,NY. 1991; 423-426.
  361. Hsieh CL, Bowcock AM, Farrer LA, Hebert JM, Huang KN, Cavalli-Sforza LL, Julius D, Francke U. The serotonin receptor subtype 2 locus HTR2 is on human chromosome 13 near genes for esterase D and retinoblastoma-1 and on mouse chromosome 14. Somat Cell Mol Genet. 1990 Nov; 16(6):567-74. PMID: 1980030.
    View in: PubMed
  362. St George-Hyslop PH, Haines JL, Farrer LA, Polinsky R, Van Broeckhoven C, Goate A, McLachlan DR, Orr H, Bruni AC, Sorbi S, Rainero I, Foncin JF, Pollen D, Cantu JM, Tupler R, Voskresenskaya N, Mayeux R, Growden J, Fried VA, Myers RH, Nee L, Backhovens H, Martin JJ, Rossor M, Owen MJ, Mullan M, Percy ME, Karlinsky H, Rich S, Heston L, Montesi M, Mortilla M, Nacmias N, Gusella JF, Hardy JA, et al. Genetic linkage studies suggest that Alzheimer's disease is not a single homogeneous disorder. Nature. 1990 Sep 13; 347(6289):194-7. PMID: 2395471.
    View in: PubMed
  363. Bonné-Tamir B, Frydman M, Agger MS, Bekeer R, Bowcock AM, Hebert JM, Cavalli-Sforza LL, Farrer LA. Wilson's disease in Israel: a genetic and epidemiological study. Ann Hum Genet. 1990 May; 54(Pt 2):155-68. PMID: 2382969.
    View in: PubMed
  364. Warren AC, Bowcock AM, Farrer LA, Antonarakis SE. An alpha satellite DNA polymorphism specific for the centromeric region of chromosome 13. Genomics. 1990 May; 7(1):110-4. PMID: 1970794.
    View in: PubMed
  365. Farrer LA, Myers RH, Cupples LA, St George-Hyslop PH, Bird TD, Rossor MN, Mullan MJ, Polinsky R, Nee L, Heston L, et al. Transmission and age-at-onset patterns in familial Alzheimer's disease: evidence for heterogeneity. Neurology. 1990 Mar; 40(3 Pt 1):395-403. PMID: 2314579.
    View in: PubMed
  366. Breitner JC. Estimation of familial risk in Alzheimer's disease. Ann Neurol. 1990 Mar; 27(3):338-40. PMID: 2327743.
    View in: PubMed
  367. St George-Hyslop PH, Haines JL, Polinsky RJ, Tanzi RE, Farrer L, Myers RH, Gusella JF. Molecular genetics of familial Alzheimer's disease. Can J Neurol Sci. 1989 Nov; 16(4 Suppl):465-7. PMID: 2680005.
    View in: PubMed
  368. Myers RH, Leavitt J, Farrer LA, Jagadeesh J, McFarlane H, Mastromauro CA, Mark RJ, Gusella JF. Homozygote for Huntington disease. Am J Hum Genet. 1989 Oct; 45(4):615-8. PMID: 2535231.
    View in: PubMed
  369. St George-Hyslop PH, Myers RH, Haines JL, Farrer LA, Tanzi RE, Abe K, James MF, Conneally PM, Polinsky RJ, Gusella JF. Familial Alzheimer's disease: progress and problems. Neurobiol Aging. 1989 Sep-Oct; 10(5):417-25. PMID: 2682321.
    View in: PubMed
  370. Farrer LA, O'Sullivan DM, Cupples LA, Growdon JH, Myers RH. Assessment of genetic risk for Alzheimer's disease among first-degree relatives. Ann Neurol. 1989 May; 25(5):485-93. PMID: 2774490.
    View in: PubMed
  371. Haines JL, Farrer LA, Myers RH. Linkage map of anonymous loci near the CF gene. Prog Clin Biol Res. 1989; 329:29-34. PMID: 2622958.
    View in: PubMed
  372. St George-Hyslop PH, Tanzi RE, Haines JL, Polinsky RJ, Farrer L, Myers RH, Gusella JF. Molecular genetics of familial Alzheimer's disease. Eur Neurol. 1989; 29 Suppl 3:25-7. PMID: 2693103.
    View in: PubMed
  373. Bowcock AM, Farrer LA, Hebert JM, Agger M, Sternlieb I, Schienberg IH, Buys CHCM, Scheffer H, Frydman M, Chajek-Saul T, Bonné-Tamir B, Cavalli-Sforza LL. DNA markers at 13q14-q22 linked to Wilson's disease. In: Molecular Probes. Albertini A, Paoletti R, Reisfeld RA (eds). Raven Press. New York,NY. 1989; 51-60.
  374. Farrer LA, Florio LP, Bruce ML, Leaf PJ, Weissman MM. Reliability of self-reported age at onset of major depression. J Psychiatr Res. 1989; 23(1):35-47. PMID: 2754627.
    View in: PubMed
  375. Bowcock AM, Farrer LA, Hebert JM, Agger M, Sternlieb I, Scheinberg IH, Buys CH, Scheffer H, Frydman M, Chajek-Saul T, et al. Eight closely linked loci place the Wilson disease locus within 13q14-q21. Am J Hum Genet. 1988 Nov; 43(5):664-74. PMID: 3189332.
    View in: PubMed
  376. Farrer LA, Myers RH, Cupples LA, Conneally PM. Considerations in using linkage analysis as a presymptomatic test for Huntington's disease. J Med Genet. 1988 Sep; 25(9):577-88. PMID: 2903248.
    View in: PubMed
  377. Farrer LA, Castiglione CM, Kidd JR, Myers S, Carson N, Simpson NE, Kidd KK. A linkage group of five DNA markers on human chromosome 10. Genomics. 1988 Jul; 3(1):72-7. PMID: 2906045.
    View in: PubMed
  378. Farrer LA, Bonne-Tamir B, Frydman M, Magazanik A, Kidd KK, Bowcock AM, Cavalli-Sforza LL. Predicting genotypes at loci for autosomal recessive disorders using linked genetic markers: application to Wilson's disease. Hum Genet. 1988 Jun; 79(2):109-17. PMID: 3164701.
    View in: PubMed
  379. Meissen GJ, Myers RH, Mastromauro CA, Koroshetz WJ, Klinger KW, Farrer LA, Watkins PA, Gusella JF, Bird ED, Martin JB. Predictive testing for Huntington's disease with use of a linked DNA marker. N Engl J Med. 1988 Mar 3; 318(9):535-42. PMID: 2893260.
    View in: PubMed
  380. St. George-Hyslop P, Haines J, Farrer LA, Tanzi R, Hobbs W, Polinsky RJ, Nee L, Sorbi S, Piacentini S, Amaducci L, Heston L, Orr H, Crapper-MacLachan D, Frommelt P, Foncin JF, Bruni A, Wexler N, Mayeux R, Hardy J, Goate A, Williamson R, Myers RH, Feldman R, O'Sullivan DM, Drachman D, Pollen D, Stowe R, Growdon JH, Conneally PM, Gusella JF . Molecular genetics of autosomal dominant familial Alzheimer's disease. In: Finch CE, Davies P (eds). Current Communications in Molecular Biology. Cold Spring Harbor Laboratory. New York,NY. 1988; 159-168.
  381. Farrer LA, Goodfellow PJ, White BN, Holden JJ, Kidd JR, Simpson NE, Kidd KK. Linkage analysis of multiple endocrine neoplasia type 2A (MEN-2A) and three DNA markers on chromosome 20: evidence against synteny. Cancer Genet Cytogenet. 1987 Aug; 27(2):327-34. PMID: 2885081.
    View in: PubMed
  382. Simpson NE, Kidd KK, Goodfellow PJ, McDermid H, Myers S, Kidd JR, Jackson CE, Duncan AM, Farrer LA, Brasch K, et al. Assignment of multiple endocrine neoplasia type 2A to chromosome 10 by linkage. Nature. 1987 Aug 6-12; 328(6130):528-30. PMID: 2886918.
    View in: PubMed
  383. Bowcock AM, Farrer LA, Cavalli-Sforza LL, Hebert JM, Kidd KK, Frydman M, Bonne-Tamir B. Mapping the Wilson disease locus to a cluster of linked polymorphic markers on chromosome 13. Am J Hum Genet. 1987 Jul; 41(1):27-35. PMID: 3474893.
    View in: PubMed
  384. Farrer LA, Goodfellow PJ, Lamarche CM, Franjkovic I, Myers S, White BN, Holden JJ, Kidd JR, Simpson NE, Kidd KK. An efficient strategy for gene mapping using multipoint linkage analysis: exclusion of the multiple endocrine neoplasia 2A (MEN2A) locus from chromosome 13. Am J Hum Genet. 1987 Apr; 40(4):329-37. PMID: 2883889.
    View in: PubMed
  385. Goodfellow PJ, Duncan AM, Farrer LA, Holden JJ, White BN, Kidd JR, Kidd KK, Simpson NE. Localization and linkage of three polymorphic DNA sequences on human chromosome 20. Cytogenet Cell Genet. 1987; 44(2-3):112-7. PMID: 2882953.
    View in: PubMed
  386. Farrer LA, Conneally PM. Predictability of phenotype in Huntington's disease. Arch Neurol. 1987 Jan; 44(1):109-13. PMID: 2948483.
    View in: PubMed
  387. Farrer LA . Genetic neurodegenerative disease models for human aging. Rev Biol Res Aging. 1987; 3:163-189.
  388. Bowcock AM, Farrer LA, Hebert JM, Bonne-Tamir B, Frydman M, Kidd KK, Cavalli-Sforza LL. A new human RFLP identified by 7D2 places D13S10 proximal to esterase D. Cytogenet Cell Genet. 1987; 44(4):236-7. PMID: 2884079.
    View in: PubMed
  389. Farrer LA . Letter to the Editor: Suicide and presymptomatic testing in Huntington disease. Am J Med Genet. 1987; 26:319-320.
  390. Pakstis AJ, Kidd JR, Castiglione CM, Pletcher BA, Murphy PD, Farrer LA, Genel M, Kidd KK. One large kindred excludes a locus for multiple endocrine neoplasia type 2A from about 25% of the human autosomal genetic map. Henry Ford Hosp Med J. 1987; 35(2-3):164-7. PMID: 2891651.
    View in: PubMed
  391. Meaney FJ, Farrer LA. Clinical anthropometry and medical genetics: a compilation of body measurements in genetic and congenital disorders. Am J Med Genet. 1986 Oct; 25(2):343-59. PMID: 3535502.
    View in: PubMed
  392. Farrer LA. Managing data for genetic linkage analysis. Am J Hum Genet. 1986 Jul; 39(1):146-7. PMID: 3755865.
    View in: PubMed
  393. Farrer LA. Suicide and attempted suicide in Huntington disease: implications for preclinical testing of persons at risk. Am J Med Genet. 1986 Jun; 24(2):305-11. PMID: 2940862.
    View in: PubMed
  394. Bonné-Tamir B, Farrer LA, Frydman M, Kanaaneh H. Evidence for linkage between Wilson disease and esterase D in three kindreds: detection of linkage for an autosomal recessive disorder by the family study method. Genet Epidemiol. 1986; 3(3):201-9. PMID: 3459695.
    View in: PubMed
  395. Kramer PL, Farrer LA, Pakstis AJ, Kidd KK. Development of a map of chromosome 11p. Genet Epidemiol Suppl. 1986; 1:153-8. PMID: 3471659.
    View in: PubMed
  396. Farrer LA, Meaney FJ. An anthropometric assessment of Huntington's disease patients and families. Am J Phys Anthropol. 1985 Jul; 67(3):185-94. PMID: 2932916.
    View in: PubMed
  397. Farrer LA, Yu PL. Anthropometric discrimination among affected, at-risk, and not-at-risk individuals in families with Huntington disease. Am J Med Genet. 1985 Jun; 21(2):307-16. PMID: 3160237.
    View in: PubMed
  398. Frydman M, Bonné-Tamir B, Farrer LA, Conneally PM, Magazanik A, Ashbel S, Goldwitch Z. Assignment of the gene for Wilson disease to chromosome 13: linkage to the esterase D locus. Proc Natl Acad Sci U S A. 1985 Mar; 82(6):1819-21. PMID: 3856863.
    View in: PubMed
  399. Farrer LA, Conneally PM. A genetic model for age at onset in Huntington disease. Am J Hum Genet. 1985 Mar; 37(2):350-7. PMID: 3157315.
    View in: PubMed
  400. Farrer LA, Haines JL, Yount EA. Automating data manipulation for genetic analysis using a data base management system. Hum Hered. 1985; 35(5):296-301. PMID: 3840122.
    View in: PubMed
  401. Yount EA, Farrer LA, Wallace MR . Application of database techniques in medical genetics. In: Walker RM, ed. Proceedings: Eighteenth Hawaii International Conference of System Sciences III. 1985; 30-38.
  402. Farrer LA. Diabetes mellitus in Huntington disease. Clin Genet. 1985 Jan; 27(1):62-7. PMID: 3156696.
    View in: PubMed
  403. Farrer LA, Conneally PM, Yu PL. The natural history of Huntington disease: possible role of "aging genes". Am J Med Genet. 1984 May; 18(1):115-23. PMID: 6234800.
    View in: PubMed
Lindsay's Networks
Click the "See All" links for more information and interactive visualizations!
Concepts
_
BU Co-Authors
_
Similar BU People
_
Same Department