Keywords
Last Name

Vinod Vathipadiekal, PhD

TitleHTP Fellow
InstitutionBoston University School of Medicine
DepartmentMedicine
DivisionThe Center of Excellence in Sickle Cell Disease
Address72 E. Concord Street
Boston MA 02118
Phone(617) 638-7527
ORCID ORCID Icon0000-0002-8181-6890
 Awards and Honors

Start-EndDescription
2012American Association for Cancer Research: AACR-Bristol-Myers Squibb Oncology Scholar-in-Training Award
2011-2012MGH Cancer Center, Boston: von der Luft Award for Ovarian Cancer Research
2011MGH's Executive Committee On Research, Boston: Poster of Distinction Award
2006International Union of Biochemistry and Molecular Biology: IUBMB Young Scientists Award
2005Department of Science and Technology, Govt. of India: Department of Science and Technology Award
2004National Chemical Laboratory, CSIR, India: Best Research Scholar Award
2004Biotechnology Society of India: Best Poster Award
2002National Chemical Laboratory, CSIR, India : Best Research Paper Award
 Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Vathipadiekal V, Farrell JJ, Wang S, Edward HL, Shappell H, Al-Rubaish AM, Al-Muhanna F, Naserullah Z, Alsuliman A, Qutub HO, Simkin I, Farrer LA, Jiang Z, Luo HY, Huang S, Mostoslavsky G, Murphy GJ, Patra PK, Chui DH, Alsultan A, Al-Ali AK, Sebastiani P, Steinberg MH. A candidate transacting modulator of fetal hemoglobin gene expression in the Arab-Indian haplotype of sickle cell anemia. Am J Hematol. 2016 Nov; 91(11):1118-1122. PMID: 27501013.
    View in: PubMed
  2. Sosulski A, Horn H, Zhang L, Coletti C, Vathipadiekal V, Castro CM, Birrer MJ, Nagano O, Saya H, Lage K, Donahoe PK, Pépin D. CD44 Splice Variant v8-10 as a Marker of Serous Ovarian Cancer Prognosis. PLoS One. 2016; 11(6):e0156595. PMID: 27253518.
    View in: PubMed
  3. Vathipadiekal V, Alsultan A, Baltrusaitis K, Farrell JJ, Al-Rubaish AM, Al-Muhanna F, Naserullah Z, Suliman A, Patra PK, Milton JN, Farrer LA, Chui DH, Al-Ali AK, Sebastiani P, Steinberg MH. Homozygosity for a haplotype in the HBG2-OR51B4 region is exclusive to Arab-Indian haplotype sickle cell anemia. Am J Hematol. 2016 Jun; 91(6):E308-11. PMID: 27185208.
    View in: PubMed
  4. Pépin D, Sosulski A, Zhang L, Wang D, Vathipadiekal V, Hendren K, Coletti CM, Yu A, Castro CM, Birrer MJ, Gao G, Donahoe PK. AAV9 delivering a modified human Mullerian inhibiting substance as a gene therapy in patient-derived xenografts of ovarian cancer. Proc Natl Acad Sci U S A. 2015 Aug 11; 112(32):E4418-27. PMID: 26216943.
    View in: PubMed
  5. Vathipadiekal V, Wang V, Wei W, Waldron L, Drapkin R, Gillette M, Skates S, Birrer M. Creation of a Human Secretome: A Novel Composite Library of Human Secreted Proteins: Validation Using Ovarian Cancer Gene Expression Data and a Virtual Secretome Array. Clin Cancer Res. 2015 Nov 1; 21(21):4960-9. PMID: 25944803.
    View in: PubMed
  6. Tyekucheva S, Martin NE, Stack EC, Wei W, Vathipadiekal V, Waldron L, Fiorentino M, Lis RT, Stampfer MJ, Loda M, Parmigiani G, Mucci LA, Birrer M. Comparing Platforms for Messenger RNA Expression Profiling of Archival Formalin-Fixed, Paraffin-Embedded Tissues. J Mol Diagn. 2015 Jul; 17(4):374-81. PMID: 25937617.
    View in: PubMed
  7. Sebastiani P, Farrell JJ, Alsultan A, Wang S, Edward HL, Shappell H, Bae H, Milton JN, Baldwin CT, Al-Rubaish AM, Naserullah Z, Al-Muhanna F, Alsuliman A, Patra PK, Farrer LA, Ngo D, Vathipadiekal V, Chui DH, Al-Ali AK, Steinberg MH. BCL11A enhancer haplotypes and fetal hemoglobin in sickle cell anemia. Blood Cells Mol Dis. 2015 Mar; 54(3):224-30. PMID: 25703683.
    View in: PubMed
  8. Wei W, Dizon D, Vathipadiekal V, Birrer MJ. Ovarian cancer: genomic analysis. Ann Oncol. 2013 Dec; 24 Suppl 10:x7-15. PMID: 24265410.
    View in: PubMed
  9. He L, Guo L, Vathipadiekal V, Sergent PA, Growdon WB, Engler DA, Rueda BR, Birrer MJ, Orsulic S, Mohapatra G. Identification of LMX1B as a novel oncogene in human ovarian cancer. Oncogene. 2014 Aug 14; 33(33):4226-35. PMID: 24056967.
    View in: PubMed
  10. Farley J, Brady WE, Vathipadiekal V, Lankes HA, Coleman R, Morgan MA, Mannel R, Yamada SD, Mutch D, Rodgers WH, Birrer M, Gershenson DM. Selumetinib in women with recurrent low-grade serous carcinoma of the ovary or peritoneum: an open-label, single-arm, phase 2 study. Lancet Oncol. 2013 Feb; 14(2):134-40. PMID: 23261356.
    View in: PubMed
  11. May T, Shoni M, Crum CP, Xian W, Vathipadiekal V, Birrer M, Rosen B, Tone A, Murphy KJ. Low-grade and high-grade serous Mullerian carcinoma: review and analysis of publicly available gene expression profiles. Gynecol Oncol. 2013 Mar; 128(3):488-92. PMID: 23253401.
    View in: PubMed
  12. Sethi G, Pathak HB, Zhang H, Zhou Y, Einarson MB, Vathipadiekal V, Gunewardena S, Birrer MJ, Godwin AK. An RNA interference lethality screen of the human druggable genome to identify molecular vulnerabilities in epithelial ovarian cancer. PLoS One. 2012; 7(10):e47086. PMID: 23056589.
    View in: PubMed
  13. Li H, Cai Q, Wu H, Vathipadiekal V, Dobbin ZC, Li T, Hua X, Landen CN, Birrer MJ, Sánchez-Beato M, Zhang R. SUZ12 promotes human epithelial ovarian cancer by suppressing apoptosis via silencing HRK. Mol Cancer Res. 2012 Nov; 10(11):1462-72. PMID: 22964433.
    View in: PubMed
  14. Verma A, White M, Vathipadiekal V, Tripathi S, Mbianda J, Ieong M, Qi L, Taubenberger JK, Takahashi K, Jensenius JC, Thiel S, Hartshorn KL. Human H-ficolin inhibits replication of seasonal and pandemic influenza A viruses. J Immunol. 2012 Sep 1; 189(5):2478-87. PMID: 22851708.
    View in: PubMed
  15. Vathipadiekal V, Saxena D, Mok SC, Hauschka PV, Ozbun L, Birrer MJ. Identification of a potential ovarian cancer stem cell gene expression profile from advanced stage papillary serous ovarian cancer. PLoS One. 2012; 7(1):e29079. PMID: 22272227.
    View in: PubMed
  16. Li H, Bitler BG, Vathipadiekal V, Maradeo ME, Slifker M, Creasy CL, Tummino PJ, Cairns P, Birrer MJ, Zhang R. ALDH1A1 is a novel EZH2 target gene in epithelial ovarian cancer identified by genome-wide approaches. Cancer Prev Res (Phila). 2012 Mar; 5(3):484-91. PMID: 22144423.
    View in: PubMed
  17. McCann CK, Growdon WB, Kulkarni-Datar K, Curley MD, Friel AM, Proctor JL, Sheikh H, Deyneko I, Ferguson JA, Vathipadiekal V, Birrer MJ, Borger DR, Mohapatra G, Zukerberg LR, Foster R, Macdougall JR, Rueda BR. Inhibition of Hedgehog signaling antagonizes serous ovarian cancer growth in a primary xenograft model. PLoS One. 2011; 6(11):e28077. PMID: 22140510.
    View in: PubMed
  18. Stany MP, Vathipadiekal V, Ozbun L, Stone RL, Mok SC, Xue H, Kagami T, Wang Y, McAlpine JN, Bowtell D, Gout PW, Miller DM, Gilks CB, Huntsman DG, Ellard SL, Wang YZ, Vivas-Mejia P, Lopez-Berestein G, Sood AK, Birrer MJ. Identification of novel therapeutic targets in microdissected clear cell ovarian cancers. PLoS One. 2011; 6(7):e21121. PMID: 21754983.
    View in: PubMed
  19. Vathipadiekal V, Rao M, . Encyclopedia of Nanoscience and Nanotechnology. Nanobiocomposites for Baiocatalysis. American Scientific Publishers. 2011; 16:539.
  20. Mok SC, Bonome T, Vathipadiekal V, Bell A, Johnson ME, Wong KK, Park DC, Hao K, Yip DK, Donninger H, Ozbun L, Samimi G, Brady J, Randonovich M, Pise-Masison CA, Barrett JC, Wong WH, Welch WR, Berkowitz RS, Birrer MJ. A gene signature predictive for outcome in advanced ovarian cancer identifies a survival factor: microfibril-associated glycoprotein 2. Cancer Cell. 2009 Dec 8; 16(6):521-32. PMID: 19962670.
    View in: PubMed
  21. Vathipadiekal V, Umasankar PK, Patole MS, Rao M. Molecular cloning, over expression, and activity studies of a peptidic HIV-1 protease inhibitor: designed synthetic gene to functional recombinant peptide. Peptides. 2010 Jan; 31(1):16-21. PMID: 19818820.
    View in: PubMed
  22. Ozbun L, Vathipadiekal V, Radonovich ME, Pise-Masison C, Saxena D, Hauschka PV, Mok SC, Birrer MJ. Cancer stem cell gene signature of ovarian tumor side populations. J Clin Oncol. 2008 May 20; 26(15_suppl):5546. PMID: 27950484.
    View in: PubMed
  23. Vinod VP, Phadtare S, Joshi HM, Sastry M, Rao M. Fabrication, characterization, and enzymatic activity of fungal protease--nanogold membrane bioconjugate. J Nanosci Nanotechnol. 2007 Aug; 7(8):2767-73. PMID: 17685295.
    View in: PubMed
  24. Vathipadiekal V, Verma A, Rao M. Glycine-assisted enhancement of 1,4-beta-d-xylan xylanohydrolase activity at alkaline pH with a pH optimum shift. Biol Chem. 2007 Jan; 388(1):61-5. PMID: 17214550.
    View in: PubMed
  25. Vinod VP, Shinde S, D'Britto V, Shukla PG, Rao M. Preparation and characterization of urea-formaldehyde-pepsin bioconjugate: a new biocatalyst system. Biotechnol Prog. 2006 Nov-Dec; 22(6):1585-90. PMID: 17137305.
    View in: PubMed
  26. Kulkarni MJ, Vinod VP, Umasankar PK, Patole MS, Rao M. Intact cell matrix-assisted laser desorption/ionization mass spectrometry as a tool to screen drugs in vivo for regulation of protein expression. Rapid Commun Mass Spectrom. 2006; 20(18):2769-72. PMID: 16921561.
    View in: PubMed
  27. Vathipadiekal V, Prem NP, Rao M. Adv. Biotech. Beta-Secretase: A potential therapeutic target in Alzheimer’s disease. 2005; 12.
  28. Vathipadiekal V, Rao M. Inhibition of 1,4-beta-D-xylan xylanohydrolase by the specific aspartic protease inhibitor pepstatin: probing the two-step inhibition mechanism. J Biol Chem. 2004 Nov 5; 279(45):47024-33. PMID: 15317808.
    View in: PubMed
  29. Phadtare S, Vinod VP, Wadgaonkar PP, Rao M, Sastry M. Free-standing nanogold membranes as scaffolds for enzyme immobilization. Langmuir. 2004 Apr 27; 20(9):3717-23. PMID: 15875405.
    View in: PubMed
  30. Phadtare S, Vinod VP, Mukhopadhyay K, Kumar A, Rao M, Chaudhari RV, Sastry M. Immobilization and biocatalytic activity of fungal protease on gold nanoparticle-loaded zeolite microspheres. Biotechnol Bioeng. 2004 Mar 20; 85(6):629-37. PMID: 14966804.
    View in: PubMed
  31. Vathipadiekal V, Phadtare, S, Sastry, M, Rao M. Plant, Microbes and Biotechnology. Pointer Publishers. 2004; 1-13.
  32. Phadtare S, Kumar A, Vinod VP, Dash C, Palaskar DV, Rao M, Shukla PG, Sivaram S, Sastry M . Direct Assembly of Gold Nanoparticle “Shells” on Polyurethane Microsphere “Cores” and Their Application as Enzyme Immobilization Templates. Chem. Mater. 2003; 10(15):1944–1949.
  33. Kausik Mukhopadhyay, Sumant Phadtare, V. P. Vinod, Ashavani Kumar, Mala Rao, Raghunath V. Chaudhari, and Murali Sastry. Gold Nanoparticles Assembled on Amine-Functionalized Na-Y Zeolite:? A Biocompatible Surface for Enzyme Immobilization. Langmuir. 2003; 9(19):3858–3863.
  34. Phadtare S, Dash C, Gole A, Vinod VP, Rao M, Sastry M. Improved performance of preordered fungal protease-stearic acid biocomposites: enhanced catalytic activity, reusability, and temporal stability. Biotechnol Prog. 2002 Jul-Aug; 18(4):700-5. PMID: 12153301.
    View in: PubMed
  35. Dash C, Vathipadiekal V, George SP, Rao M. Slow-tight binding inhibition of xylanase by an aspartic protease inhibitor: kinetic parameters and conformational changes that determine the affinity and selectivity of the bifunctional nature of the inhibitor. J Biol Chem. 2002 May 17; 277(20):17978-86. PMID: 11844793.
    View in: PubMed
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