Vinod Vathipadiekal | Profiles RNS

Vinod Vathipadiekal, PhD

HTP Fellow (previously held)

Boston University Chobanian & Avedisian School of Medicine

Medicine

The Center of Excellence in Sickle Cell Disease

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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LaFargue CJ, Amero P, Noh K, Mangala LS, Wen Y, Bayraktar E, Umamaheswaran S, Stur E, Dasari SK, Ivan C, Pradeep S, Yoo W, Lu C, Jennings NB, Vathipadiekal V, Hu W, Chelariu-Raicu A, Ku Z, Deng H, Xiong W, Choi HJ, Hu M, Kiyama T, Mao CA, Ali-Fehmi R, Birrer MJ, Liu J, Zhang N, Lopez-Berestein G, de Franciscis V, An Z, Sood AK. Overcoming adaptive resistance to anti-VEGF therapy by targeting CD5L. Nat Commun. 2023 Apr 26; 14(1):2407. PMID: 37100807; PMCID: PMC10133315; DOI: 10.1038/s41467-023-36910-5;

Byrne M, Vathipadiekal V, Apponi L, Iwamoto N, Kandasamy P, Longo K, Liu F, Looby R, Norwood L, Shah A, Shelke JD, Shivalila C, Yang H, Yin Y, Guo L, Bowman K, Vargeese C. Stereochemistry Enhances Potency, Efficacy, and Durability of Malat1 Antisense Oligonucleotides In Vitro and In Vivo in Multiple Species. Transl Vis Sci Technol. 2021 01; 10(1):23. PMID: 33510962; PMCID: PMC7804567; DOI: 10.1167/tvst.10.1.23;

Vathipadiekal V, Farrell JJ, Wang S, Edward HL, Shappell H, Al-Rubaish AM, Al-Muhanna F, Naserullah Z, Alsuliman A, Qutub HO, Simkin I, Farrer LA, Jiang Z, Luo HY, Huang S, Mostoslavsky G, Murphy GJ, Patra PK, Chui DH, Alsultan A, Al-Ali AK, Sebastiani P, Steinberg MH. A candidate transacting modulator of fetal hemoglobin gene expression in the Arab-Indian haplotype of sickle cell anemia. Am J Hematol. 2016 Nov; 91(11):1118-1122.View Related Profiles.

Chui, David
Murphy, George
Mostoslavsky, Gustavo
Luo, Hong
Farrer, Lindsay
Steinberg, Martin
Sebastiani, Paola
Vathipadiekal, Vinod
Jiang, Zhihua

PMID: 27501013; PMCID: PMC5072989; DOI: 10.1002/ajh.24527;

Sosulski A, Horn H, Zhang L, Coletti C, Vathipadiekal V, Castro CM, Birrer MJ, Nagano O, Saya H, Lage K, Donahoe PK, Pépin D. CD44 Splice Variant v8-10 as a Marker of Serous Ovarian Cancer Prognosis. PLoS One. 2016; 11(6):e0156595. PMID: 27253518; PMCID: PMC4890777; DOI: 10.1371/journal.pone.0156595;

Vathipadiekal V, Alsultan A, Baltrusaitis K, Farrell JJ, Al-Rubaish AM, Al-Muhanna F, Naserullah Z, Suliman A, Patra PK, Milton JN, Farrer LA, Chui DH, Al-Ali AK, Sebastiani P, Steinberg MH. Homozygosity for a haplotype in the HBG2-OR51B4 region is exclusive to Arab-Indian haplotype sickle cell anemia. Am J Hematol. 2016 06; 91(6):E308-11.View Related Profiles.

Chui, David
Hicks, Jacqueline
Farrer, Lindsay
Steinberg, Martin
Sebastiani, Paola
Vathipadiekal, Vinod

PMID: 27185208; PMCID: PMC4874527; DOI: 10.1002/ajh.24368;

Pépin D, Sosulski A, Zhang L, Wang D, Vathipadiekal V, Hendren K, Coletti CM, Yu A, Castro CM, Birrer MJ, Gao G, Donahoe PK. AAV9 delivering a modified human Mullerian inhibiting substance as a gene therapy in patient-derived xenografts of ovarian cancer. Proc Natl Acad Sci U S A. 2015 Aug 11; 112(32):E4418-27. PMID: 26216943; PMCID: PMC4538667; DOI: 10.1073/pnas.1510604112;

Vathipadiekal V, Wang V, Wei W, Waldron L, Drapkin R, Gillette M, Skates S, Birrer M. Creation of a Human Secretome: A Novel Composite Library of Human Secreted Proteins: Validation Using Ovarian Cancer Gene Expression Data and a Virtual Secretome Array. Clin Cancer Res. 2015 Nov 1; 21(21):4960-9. PMID: 25944803; DOI: 10.1158/1078-0432.CCR-14-3173;

Tyekucheva S, Martin NE, Stack EC, Wei W, Vathipadiekal V, Waldron L, Fiorentino M, Lis RT, Stampfer MJ, Loda M, Parmigiani G, Mucci LA, Birrer M. Comparing Platforms for Messenger RNA Expression Profiling of Archival Formalin-Fixed, Paraffin-Embedded Tissues. J Mol Diagn. 2015 Jul; 17(4):374-81. PMID: 25937617; PMCID: PMC4483460; DOI: 10.1016/j.jmoldx.2015.02.002;

Sebastiani P, Farrell JJ, Alsultan A, Wang S, Edward HL, Shappell H, Bae H, Milton JN, Baldwin CT, Al-Rubaish AM, Naserullah Z, Al-Muhanna F, Alsuliman A, Patra PK, Farrer LA, Ngo D, Vathipadiekal V, Chui DH, Al-Ali AK, Steinberg MH. BCL11A enhancer haplotypes and fetal hemoglobin in sickle cell anemia. Blood Cells Mol Dis. 2015 Mar; 54(3):224-30.View Related Profiles.

Chui, David
Ngo, Doan
Ngo, Duyen
Hicks, Jacqueline
Farrer, Lindsay
Steinberg, Martin
Sebastiani, Paola
Vathipadiekal, Vinod

PMID: 25703683; PMCID: PMC4341902; DOI: 10.1016/j.bcmd.2015.01.001;

Wei W, Dizon D, Vathipadiekal V, Birrer MJ. Ovarian cancer: genomic analysis. Ann Oncol. 2013 Dec; 24 Suppl 10:x7-15. PMID: 24265410; PMCID: PMC3836569; DOI: 10.1093/annonc/mdt462;

Showing 10 of 37 results. Show More

He L, Guo L, Vathipadiekal V, Sergent PA, Growdon WB, Engler DA, Rueda BR, Birrer MJ, Orsulic S, Mohapatra G. Identification of LMX1B as a novel oncogene in human ovarian cancer. Oncogene. 2014 Aug 14; 33(33):4226-35. PMID: 24056967; DOI: 10.1038/onc.2013.375;

Farley J, Brady WE, Vathipadiekal V, Lankes HA, Coleman R, Morgan MA, Mannel R, Yamada SD, Mutch D, Rodgers WH, Birrer M, Gershenson DM. Selumetinib in women with recurrent low-grade serous carcinoma of the ovary or peritoneum: an open-label, single-arm, phase 2 study. Lancet Oncol. 2013 Feb; 14(2):134-40. PMID: 23261356; PMCID: PMC3627419; DOI: 10.1016/S1470-2045(12)70572-7;

May T, Shoni M, Crum CP, Xian W, Vathipadiekal V, Birrer M, Rosen B, Tone A, Murphy KJ. Low-grade and high-grade serous Mullerian carcinoma: review and analysis of publicly available gene expression profiles. Gynecol Oncol. 2013 Mar; 128(3):488-92. PMID: 23253401; DOI: 10.1016/j.ygyno.2012.12.009;

Sethi G, Pathak HB, Zhang H, Zhou Y, Einarson MB, Vathipadiekal V, Gunewardena S, Birrer MJ, Godwin AK. An RNA interference lethality screen of the human druggable genome to identify molecular vulnerabilities in epithelial ovarian cancer. PLoS One. 2012; 7(10):e47086. PMID: 23056589; PMCID: PMC3467214; DOI: 10.1371/journal.pone.0047086;

Li H, Cai Q, Wu H, Vathipadiekal V, Dobbin ZC, Li T, Hua X, Landen CN, Birrer MJ, Sánchez-Beato M, Zhang R. SUZ12 promotes human epithelial ovarian cancer by suppressing apoptosis via silencing HRK. Mol Cancer Res. 2012 Nov; 10(11):1462-72. PMID: 22964433; PMCID: PMC3501543; DOI: 10.1158/1541-7786.MCR-12-0335;

Verma A, White M, Vathipadiekal V, Tripathi S, Mbianda J, Ieong M, Qi L, Taubenberger JK, Takahashi K, Jensenius JC, Thiel S, Hartshorn KL. Human H-ficolin inhibits replication of seasonal and pandemic influenza A viruses. J Immunol. 2012 Sep 1; 189(5):2478-87.View Related Profiles.

Hartshorn, Kevan
Tripathi, Shweta
Vathipadiekal, Vinod

PMID: 22851708; PMCID: PMC3650843; DOI: 10.4049/jimmunol.1103786;

Vathipadiekal V, Saxena D, Mok SC, Hauschka PV, Ozbun L, Birrer MJ. Identification of a potential ovarian cancer stem cell gene expression profile from advanced stage papillary serous ovarian cancer. PLoS One. 2012; 7(1):e29079. PMID: 22272227; PMCID: PMC3260150; DOI: 10.1371/journal.pone.0029079;

Li H, Bitler BG, Vathipadiekal V, Maradeo ME, Slifker M, Creasy CL, Tummino PJ, Cairns P, Birrer MJ, Zhang R. ALDH1A1 is a novel EZH2 target gene in epithelial ovarian cancer identified by genome-wide approaches. Cancer Prev Res (Phila). 2012 Mar; 5(3):484-91. PMID: 22144423; PMCID: PMC3294119; DOI: 10.1158/1940-6207.CAPR-11-0414;

McCann CK, Growdon WB, Kulkarni-Datar K, Curley MD, Friel AM, Proctor JL, Sheikh H, Deyneko I, Ferguson JA, Vathipadiekal V, Birrer MJ, Borger DR, Mohapatra G, Zukerberg LR, Foster R, Macdougall JR, Rueda BR. Inhibition of Hedgehog signaling antagonizes serous ovarian cancer growth in a primary xenograft model. PLoS One. 2011; 6(11):e28077. PMID: 22140510; PMCID: PMC3226669; DOI: 10.1371/journal.pone.0028077;

Stany MP, Vathipadiekal V, Ozbun L, Stone RL, Mok SC, Xue H, Kagami T, Wang Y, McAlpine JN, Bowtell D, Gout PW, Miller DM, Gilks CB, Huntsman DG, Ellard SL, Wang YZ, Vivas-Mejia P, Lopez-Berestein G, Sood AK, Birrer MJ. Identification of novel therapeutic targets in microdissected clear cell ovarian cancers. PLoS One. 2011; 6(7):e21121. PMID: 21754983; PMCID: PMC3130734; DOI: 10.1371/journal.pone.0021121;

Vathipadiekal V, Rao M, . Encyclopedia of Nanoscience and Nanotechnology. Nanobiocomposites for Baiocatalysis. American Scientific Publishers. 2011; 16:539.

Mok SC, Bonome T, Vathipadiekal V, Bell A, Johnson ME, Wong KK, Park DC, Hao K, Yip DK, Donninger H, Ozbun L, Samimi G, Brady J, Randonovich M, Pise-Masison CA, Barrett JC, Wong WH, Welch WR, Berkowitz RS, Birrer MJ. A gene signature predictive for outcome in advanced ovarian cancer identifies a survival factor: microfibril-associated glycoprotein 2. Cancer Cell. 2009 Dec 8; 16(6):521-32. PMID: 19962670; PMCID: PMC3008560; DOI: 10.1016/j.ccr.2009.10.018;

Vathipadiekal V, Umasankar PK, Patole MS, Rao M. Molecular cloning, over expression, and activity studies of a peptidic HIV-1 protease inhibitor: designed synthetic gene to functional recombinant peptide. Peptides. 2010 Jan; 31(1):16-21. PMID: 19818820; DOI: 10.1016/j.peptides.2009.09.034;

Ozbun L, Vathipadiekal V, Radonovich ME, Pise-Masison C, Saxena D, Hauschka PV, Mok SC, Birrer MJ. Cancer stem cell gene signature of ovarian tumor side populations. J Clin Oncol. 2008 May 20; 26(15_suppl):5546. PMID: 27950484

Vinod VP, Phadtare S, Joshi HM, Sastry M, Rao M. Fabrication, characterization, and enzymatic activity of fungal protease--nanogold membrane bioconjugate. J Nanosci Nanotechnol. 2007 Aug; 7(8):2767-73. PMID: 17685295

Vathipadiekal V, Verma A, Rao M. Glycine-assisted enhancement of 1,4-beta-d-xylan xylanohydrolase activity at alkaline pH with a pH optimum shift. Biol Chem. 2007 Jan; 388(1):61-5. PMID: 17214550

Vinod VP, Shinde S, D'Britto V, Shukla PG, Rao M. Preparation and characterization of urea-formaldehyde-pepsin bioconjugate: a new biocatalyst system. Biotechnol Prog. 2006 Nov-Dec; 22(6):1585-90. PMID: 17137305; DOI: 10.1021/bp0602247;

Kulkarni MJ, Vinod VP, Umasankar PK, Patole MS, Rao M. Intact cell matrix-assisted laser desorption/ionization mass spectrometry as a tool to screen drugs in vivo for regulation of protein expression. Rapid Commun Mass Spectrom. 2006; 20(18):2769-72. PMID: 16921561; DOI: 10.1002/rcm.2675;

Vathipadiekal V, Prem NP, Rao M. Adv. Biotech. Beta-Secretase: A potential therapeutic target in Alzheimer’s disease. 2005; 12.

Vathipadiekal V, Rao M. Inhibition of 1,4-beta-D-xylan xylanohydrolase by the specific aspartic protease inhibitor pepstatin: probing the two-step inhibition mechanism. J Biol Chem. 2004 Nov 5; 279(45):47024-33. PMID: 15317808

Phadtare S, Vinod VP, Wadgaonkar PP, Rao M, Sastry M. Free-standing nanogold membranes as scaffolds for enzyme immobilization. Langmuir. 2004 Apr 27; 20(9):3717-23. PMID: 15875405

Phadtare S, Vinod VP, Mukhopadhyay K, Kumar A, Rao M, Chaudhari RV, Sastry M. Immobilization and biocatalytic activity of fungal protease on gold nanoparticle-loaded zeolite microspheres. Biotechnol Bioeng. 2004 Mar 20; 85(6):629-37. PMID: 14966804; DOI: 10.1002/bit.10856;

Vathipadiekal V, Phadtare, S, Sastry, M, Rao M. Plant, Microbes and Biotechnology. Pointer Publishers. 2004; 1-13.
Phadtare S, Kumar A, Vinod VP, Dash C, Palaskar DV, Rao M, Shukla PG, Sivaram S, Sastry M . Direct Assembly of Gold Nanoparticle “Shells” on Polyurethane Microsphere “Cores” and Their Application as Enzyme Immobilization Templates. Chem. Mater. 2003; 10(15):1944–1949.
Kausik Mukhopadhyay, Sumant Phadtare, V. P. Vinod, Ashavani Kumar, Mala Rao, Raghunath V. Chaudhari, and Murali Sastry. Gold Nanoparticles Assembled on Amine-Functionalized Na-Y Zeolite:? A Biocompatible Surface for Enzyme Immobilization. Langmuir. 2003; 9(19):3858–3863.

Phadtare S, Dash C, Gole A, Vinod VP, Rao M, Sastry M. Improved performance of preordered fungal protease-stearic acid biocomposites: enhanced catalytic activity, reusability, and temporal stability. Biotechnol Prog. 2002 Jul-Aug; 18(4):700-5. PMID: 12153301; DOI: 10.1021/bp025538i;

Dash C, Vathipadiekal V, George SP, Rao M. Slow-tight binding inhibition of xylanase by an aspartic protease inhibitor: kinetic parameters and conformational changes that determine the affinity and selectivity of the bifunctional nature of the inhibitor. J Biol Chem. 2002 May 17; 277(20):17978-86. PMID: 11844793

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 37 publications over 15 distinct years, with a maximum of 6 publications in 2012

Bar chart showing 37 publications over 15 distinct years, with a maximum of 6 publications in 2012

Year	Publications
2002	2
2003	2
2004	4
2005	1
2006	2
2007	2
2008	1
2009	2
2011	4
2012	6
2013	2
2015	4
2016	3
2021	1
2023	1

2012 American Association for Cancer Research: AACR-Bristol-Myers Squibb Oncology Scholar-in-Training Award

2011 MGH's Executive Committee On Research, Boston: Poster of Distinction Award

2011-2012 MGH Cancer Center, Boston: von der Luft Award for Ovarian Cancer Research

2006 International Union of Biochemistry and Molecular Biology: IUBMB Young Scientists Award

2005 Department of Science and Technology, Govt. of India: Department of Science and Technology Award

2004 National Chemical Laboratory, CSIR, India: Best Research Scholar Award

2004 Biotechnology Society of India: Best Poster Award

2002 National Chemical Laboratory, CSIR, India : Best Research Paper Award

Contact for Mentoring:

650 Albany St Evans Biomed Research Ctr
Boston MA 02118
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617.638.7521

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