Keywords
Last Name

David Hing-Kwei Chui, MD

TitleProfessor
InstitutionBoston University School of Medicine
DepartmentMedicine
DivisionHematology & Medical Oncology
Address75 E. Newton St Evans Building
Boston MA 02118
Phone(617) 414-1018
ORCID ORCID Icon0000-0002-1475-7309
Other Positions
TitleProfessor
InstitutionBoston University School of Medicine
DepartmentPathology & Laboratory Medicine

TitleActive Staff Hospital Privileges
InstitutionBoston Medical Center
DepartmentPathology & Laboratory Medicine

 Awards and Honors

Start-EndDescription
1970-NowRoyal College of Physicians of Canada: Fellow
1971-1976Medical Research Council of Canada: Scholar
1980American Society for Clinical Investigation: elected to membership
1980-1984BLOOD: Editorial Board member
1987-1991NIH: Hematology Study Section
1991Association of American Physicians: elected to membership
2000-2002The Thalassemia Foundation of Canada: Chair, Medical Advisory Board
2002The Thalassemia Foundation of Canada: Hour Glass Award
2007-2016The Best Doctors in America
2011McGill University Alumni Association: D. Lorne Gales Award
 Research Expertise & Professional Interests
Expertise includes: Globin gene mutations; Hemoglobin diseases; Thalassmeias; and Regulation of fetal hemoglobin expression.

 Self-Described Keywords
  • Genetics
 Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Jiang Z, Luo HY, Farrell JJ, Zhang Z, Schulz VP, Albarawi D, Steinberg MH, Al-Allawi NA, Gallagher PG, Forget BG, Chui DH. A variant Sp1 (R218Q) transcription factor might enhance HbF expression in ß0 -thalassaemia homozygotes. Br J Haematol. 2017 Feb 27. PMID: 28240767.
    View in: PubMed
  2. Luo HY, Chui DH. Diverse hematological phenotypes of ß-thalassemia carriers. Ann N Y Acad Sci. 2016 Mar; 1368(1):49-55. PMID: 27123947.
    View in: PubMed
  3. Jiang Z, Luo HY, Huang S, Farrell JJ, Davis L, Théberge R, Benson KA, Riolueang S, Viprakasit V, Al-Allawi NA, Ünal S, Gümrük F, Akar N, Basak AN, Osorio L, Badens C, Pissard S, Joly P, Campbell AD, Gallagher PG, Steinberg MH, Forget BG, Chui DH. The genetic basis of asymptomatic codon 8 frame-shift (HBB:c25_26delAA) ß(0) -thalassaemia homozygotes. Br J Haematol. 2016 Mar; 172(6):958-65. PMID: 26771086.
    View in: PubMed
  4. Akinbami AO, Campbell AD, Han ZJ, Luo HY, Chui DH, Steinberg MH. Hereditary Persistence of Fetal Hemoglobin Caused by Single Nucleotide Promoter Mutations in Sickle Cell Trait and Hb SC Disease. Hemoglobin. 2016; 40(1):64-5. PMID: 26372199.
    View in: PubMed
  5. Edward HL, Pisani LA, Rodriguez-Romero WE, Chaves-Villalobos J, Garcia-Quesada J, Harris NS, Luo HY, Steinberg MH, Forget BG, Chui DH. Hb Youngstown [ß101(G3)Glu???Ala; HBB: c.305A > C]: An unstable hemoglobin variant causing severe hemolytic anemia. Hemoglobin. 2014; 38(6):381-4. PMID: 25347256.
    View in: PubMed
  6. Griffin PJ, Sebastiani P, Edward H, Baldwin CT, Gladwin MT, Gordeuk VR, Chui DH, Steinberg MH. The genetics of hemoglobin A2 regulation in sickle cell anemia. Am J Hematol. 2014 Nov; 89(11):1019-23. PMID: 25042611.
    View in: PubMed
  7. Alsultan A, Alabdulaali MK, Griffin PJ, Alsuliman AM, Ghabbour HA, Sebastiani P, Albuali WH, Al-Ali AK, Chui DH, Steinberg MH. Sickle cell disease in Saudi Arabia: the phenotype in adults with the Arab-Indian haplotype is not benign. Br J Haematol. 2014 Feb; 164(4):597-604. PMID: 24224700.
    View in: PubMed
  8. Steinberg MH, Chui DH, Dover GJ, Sebastiani P, Alsultan A. Fetal hemoglobin in sickle cell anemia: a glass half full? Blood. 2014 Jan 23; 123(4):481-5. PMID: 24222332.
    View in: PubMed
  9. Croteau SE, Luo HY, Lehmann LE, Chui DH, Neufeld EJ. Novel dominant ß-thalassemia: Hb Boston-Kuwait [codon 139/140(+T)]. Pediatr Blood Cancer. 2013 Oct; 60(10):E131-4. PMID: 23776097.
    View in: PubMed
  10. Ngo D, Bae H, Steinberg MH, Sebastiani P, Solovieff N, Baldwin CT, Melista E, Safaya S, Farrer LA, Al-Suliman AM, Albuali WH, Al Bagshi MH, Naserullah Z, Akinsheye I, Gallagher P, Luo HY, Chui DH, Farrell JJ, Al-Ali AK, Alsultan A. Fetal hemoglobin in sickle cell anemia: genetic studies of the Arab-Indian haplotype. Blood Cells Mol Dis. 2013 Jun; 51(1):22-6. PMID: 23465615.
    View in: PubMed
  11. Marks A, Luo HY, Chui DH, Greenberg J. Hemoglobin Shady Grove: a novel fetal methemoglobin variant. Pediatr Blood Cancer. 2013 Aug; 60(8):E55-6. PMID: 23460588.
    View in: PubMed
  12. Whyte D, Forget B, Chui DH, Luo HY, Pashankar F. Massive splenic infarction in an adolescent with hemoglobin S-HPFH. Pediatr Blood Cancer. 2013 Jul; 60(7):E49-51. PMID: 23281181.
    View in: PubMed
  13. Verhovsek MM, Chui DH. Pulse oximetry screening for critical congenital heart defects. Lancet. 2012 Oct 13; 380(9850):1305-6; author reply 1306. PMID: 23063278.
    View in: PubMed
  14. Verhovsek M, Shah NR, Wilcox I, Koenig SC, Barros T, Thornburg CD, Steinberg MH, Luo HY, Chui DH. Severe fetal and neonatal hemolytic anemia due to a 198 kb deletion removing the complete ß-globin gene cluster. Pediatr Blood Cancer. 2012 Nov; 59(5):941-4. PMID: 22294483.
    View in: PubMed
  15. Akinsheye I, Solovieff N, Ngo D, Malek A, Sebastiani P, Steinberg MH, Chui DH. Fetal hemoglobin in sickle cell anemia: molecular characterization of the unusually high fetal hemoglobin phenotype in African Americans. Am J Hematol. 2012 Feb; 87(2):217-9. PMID: 22139998.
    View in: PubMed
  16. Verhovsek M, So CC, O'Shea T, Gibney GT, Ma ES, Steinberg MH, Chui DH. Is HbA2 level a reliable diagnostic measurement for ß-thalassemia trait in people with iron deficiency? Am J Hematol. 2012 Jan; 87(1):114-6. PMID: 22038702.
    View in: PubMed
  17. Ngo DA, Aygun B, Akinsheye I, Hankins JS, Bhan I, Luo HY, Steinberg MH, Chui DH. Fetal haemoglobin levels and haematological characteristics of compound heterozygotes for haemoglobin S and deletional hereditary persistence of fetal haemoglobin. Br J Haematol. 2012 Jan; 156(2):259-64. PMID: 22017641.
    View in: PubMed
  18. Alsultan A, Solovieff N, Aleem A, AlGahtani FH, Al-Shehri A, Osman ME, Kurban K, Bahakim H, Al-Momen AK, Baldwin CT, Chui DH, Steinberg MH. Fetal hemoglobin in sickle cell anemia: Saudi patients from the Southwestern province have similar HBB haplotypes but higher HbF levels than African Americans. Am J Hematol. 2011 Jul; 86(7):612-4. PMID: 21630302.
    View in: PubMed
  19. Akinsheye I, Alsultan A, Solovieff N, Ngo D, Baldwin CT, Sebastiani P, Chui DH, Steinberg MH. Fetal hemoglobin in sickle cell anemia. Blood. 2011 Jul 7; 118(1):19-27. PMID: 21490337.
    View in: PubMed
  20. Giardine B, Borg J, Higgs DR, Peterson KR, Philipsen S, Maglott D, Singleton BK, Anstee DJ, Basak AN, Clark B, Costa FC, Faustino P, Fedosyuk H, Felice AE, Francina A, Galanello R, Gallivan MV, Georgitsi M, Gibbons RJ, Giordano PC, Harteveld CL, Hoyer JD, Jarvis M, Joly P, Kanavakis E, Kollia P, Menzel S, Miller W, Moradkhani K, Old J, Papachatzopoulou A, Papadakis MN, Papadopoulos P, Pavlovic S, Perseu L, Radmilovic M, Riemer C, Satta S, Schrijver I, Stojiljkovic M, Thein SL, Traeger-Synodinos J, Tully R, Wada T, Waye JS, Wiemann C, Zukic B, Chui DH, Wajcman H, Hardison RC, Patrinos GP. Systematic documentation and analysis of human genetic variation in hemoglobinopathies using the microattribution approach. Nat Genet. 2011 Apr; 43(4):295-301. PMID: 21423179.
    View in: PubMed
  21. Farrell JJ, Sherva RM, Chen ZY, Luo HY, Chu BF, Ha SY, Li CK, Lee AC, Li RC, Li CK, Yuen HL, So JC, Ma ES, Chan LC, Chan V, Sebastiani P, Farrer LA, Baldwin CT, Steinberg MH, Chui DH. A 3-bp deletion in the HBS1L-MYB intergenic region on chromosome 6q23 is associated with HbF expression. Blood. 2011 May 5; 117(18):4935-45. PMID: 21385855.
    View in: PubMed
  22. Wang W, Brugnara C, Snyder C, Wynn L, Rogers Z, Kalinyak K, Brown C, Qureshi A, Bigelow C, Neumayr L, Smith-Whitley K, Chui DH, Delahunty M, Woolson R, Steinberg M, Telen M, Kesler K. The effects of hydroxycarbamide and magnesium on haemoglobin SC disease: results of the multi-centre CHAMPS trial. Br J Haematol. 2011 Mar; 152(6):771-6. PMID: 21275961.
    View in: PubMed
  23. So CC, Chan AY, Luo HY, Verhovsek M, Chui DH, Ling SC, Chan LC. Hb A2 Hong Kong - A novel d-globin variant in a Chinese family masks the diagnosis of ß-thalassemia trait. Hemoglobin. 2011; 35(2):162-5. PMID: 21417575.
    View in: PubMed
  24. Verhovsek M, Henderson MP, Cox G, Luo HY, Steinberg MH, Chui DH. Unexpectedly low pulse oximetry measurements associated with variant hemoglobins: a systematic review. Am J Hematol. 2010 Nov; 85(11):882-5. PMID: 20890907.
    View in: PubMed
  25. Perrine SP, Castaneda SA, Chui DH, Faller DV, Berenson RJ, Siritanaratku N, Fucharoen S. Fetal globin gene inducers: novel agents and new potential. Ann N Y Acad Sci. 2010 Aug; 1202:158-64. PMID: 20712788.
    View in: PubMed
  26. Phylipsen M, Harteveld CL, de Metz M, Gallivan MV, Arkesteijn SG, Luo HY, Chui DH, Giordano PC. New and known ß-thalassemia determinants masked by known and new d gene defects [Hb A(2)-Ramallah or d6(A3)Glu?Gln, GAG>>CAG]. Hemoglobin. 2010; 34(5):445-50. PMID: 20854118.
    View in: PubMed
  27. Koenig SC, Becirevic E, Hellberg MS, Li MY, So JC, Hankins JS, Ware RE, McMahon L, Steinberg MH, Luo HY, Chui DH. Sickle cell disease caused by heterozygosity for Hb S and novel LCR deletion: Report of two patients. Am J Hematol. 2009 Sep; 84(9):603-6. PMID: 19650141.
    View in: PubMed
  28. Thornburg CD, Steinberg MH, Chui DH. Hemoglobin SE disease in Maine, and severe thalassemia in New Hampshire. J Pediatr Hematol Oncol. 2009 Apr; 31(4):307. PMID: 19346889.
    View in: PubMed
  29. Chen Z, Luo HY, Steinberg MH, Chui DH. BCL11A represses HBG transcription in K562 cells. Blood Cells Mol Dis. 2009 Mar-Apr; 42(2):144-9. PMID: 19153051.
    View in: PubMed
  30. Wilcox I, Boettger K, Greene L, Malek A, Davis L, Steinberg MH, Luo HY, Chui DH. Hemoglobin Kenya composed of alpha- and ((A)gammabeta)-fusion-globin chains, associated with hereditary persistence of fetal hemoglobin. Am J Hematol. 2009 Jan; 84(1):55-8. PMID: 19006227.
    View in: PubMed
  31. Moradkhani K, Préhu C, Old J, Henderson S, Balamitsa V, Luo HY, Poon MC, Chui DH, Wajcman H, Patrinos GP. Mutations in the paralogous human alpha-globin genes yielding identical hemoglobin variants. Ann Hematol. 2009 Jun; 88(6):535-43. PMID: 18923834.
    View in: PubMed
  32. Sedgewick AE, Timofeev N, Sebastiani P, So JC, Ma ES, Chan LC, Fucharoen G, Fucharoen S, Barbosa CG, Vardarajan BN, Farrer LA, Baldwin CT, Steinberg MH, Chui DH. BCL11A is a major HbF quantitative trait locus in three different populations with beta-hemoglobinopathies. Blood Cells Mol Dis. 2008 Nov-Dec; 41(3):255-8. PMID: 18691915.
    View in: PubMed
  33. Gibney GT, Panhuysen CI, So JC, Ma ES, Ha SY, Li CK, Lee AC, Li CK, Yuen HL, Lau YL, Johnson DM, Farrell JJ, Bisbee AB, Farrer LA, Steinberg MH, Chan LC, Chui DH. Variation and heritability of Hb F and F-cells among beta-thalassemia heterozygotes in Hong Kong. Am J Hematol. 2008 Jun; 83(6):458-64. PMID: 18266208.
    View in: PubMed
  34. Chen Z, Luo HY, Basran RK, Hsu TH, Mang DW, Nuntakarn L, Rosenfield CG, Patrinos GP, Hardison RC, Steinberg MH, Chui DH. A T-to-G transversion at nucleotide -567 upstream of HBG2 in a GATA-1 binding motif is associated with elevated hemoglobin F. Mol Cell Biol. 2008 Jul; 28(13):4386-93. PMID: 18443038.
    View in: PubMed
  35. Basran RK, Reiss UM, Luo HY, Ware RE, Chui DH. Beta-thalassemia intermedia due to compound heterozygosity for two beta-globin gene promoter mutations, including a novel TATA box deletion. Pediatr Blood Cancer. 2008 Feb; 50(2):363-6. PMID: 16732578.
    View in: PubMed
  36. Tubman VN, Bennett CM, Luo HY, Chui DH, Heeney MM. Sickle cell disease caused by Hb S/Québec-CHORI: treatment with hydroxyurea and response. Pediatr Blood Cancer. 2007 Aug; 49(2):207-10. PMID: 17551985.
    View in: PubMed
  37. Masiello D, Heeney MM, Adewoye AH, Eung SH, Luo HY, Steinberg MH, Chui DH. Hemoglobin SE disease: a concise review. Am J Hematol. 2007 Jul; 82(7):643-9. PMID: 17278112.
    View in: PubMed
  38. Andersson BA, Wering ME, Luo HY, Basran RK, Steinberg MH, Smith HP, Chui DH. Sickle cell disease due to compound heterozygosity for Hb S and a novel 7.7-kb beta-globin gene deletion. Eur J Haematol. 2007 Jan; 78(1):82-5. PMID: 17038017.
    View in: PubMed
  39. Luo HY, Heeney M, Wang WC, Eung SH, Ware RE, Steinberg MH, Chui DH. Hemoglobinopathies mimicking Hb S/beta-thalassemia: Hb S/S with alpha-thalassemia and Hb S/Volga. Am J Hematol. 2006 May; 81(5):361-5. PMID: 16628724.
    View in: PubMed
  40. Law HY, Luo HY, Wang W, Ho JF, Najmabadi H, Ng IS, Steinberg MH, Chui DH, Chong SS. Determining the cause of patchwork HBA1 and HBA2 genes: recurrent gene conversion or crossing over fixation events. Haematologica. 2006 Mar; 91(3):297-302. PMID: 16503550.
    View in: PubMed
  41. Luo HY, Tang W, Eung SH, Coad JE, Canfield P, Keller F, Crowell EH, Steinberg MH, Chui DH. Dominantly inherited beta thalassaemia intermedia caused by a new single nucleotide deletion in exon 2 of the beta globin gene: Hb morgantown (beta91 CTG>CG). J Clin Pathol. 2005 Oct; 58(10):1110-2. PMID: 16189162.
    View in: PubMed
  42. Luo HY, Boudreaux J, Steinberg MH, Chui DH. Patients with thalassemia in the United States. Blood. 2005 Jun 15; 105(12):4896-7. PMID: 15933066.
    View in: PubMed
  43. Chui DH. Alpha-thalassaemia and population health in Southeast Asia. Ann Hum Biol. 2005 Mar-Apr; 32(2):123-30. PMID: 16096207.
    View in: PubMed
  44. Lau ET, Kwok YK, Luo HY, Leung KY, Lee CP, Lam YH, Chui DH, Tang MH. Simple non-invasive prenatal detection of Hb Bart's disease by analysis of fetal erythrocytes in maternal blood. Prenat Diagn. 2005 Feb; 25(2):123-8. PMID: 15712347.
    View in: PubMed
  45. Chui DH. Alpha-thalassemia: Hb H disease and Hb Barts hydrops fetalis. Ann N Y Acad Sci. 2005; 1054:25-32. PMID: 16339648.
    View in: PubMed
  46. Basran RK, Patterson M, Walker L, Nakamura LM, Eng B, Chui DH, Waye JS. Prenatal diagnosis of hemoglobinopathies in Ontario, Canada. Ann N Y Acad Sci. 2005; 1054:507-10. PMID: 16339708.
    View in: PubMed
  47. Luo HY, Adewoye AH, Eung SH, Skelton TP, Quillen K, McMahon L, Steinberg MH, Chui DH. A novel sickle hemoglobin: hemoglobin S-south end. J Pediatr Hematol Oncol. 2004 Nov; 26(11):773-6. PMID: 15543018.
    View in: PubMed
  48. Ding C, Chiu RW, Lau TK, Leung TN, Chan LC, Chan AY, Charoenkwan P, Ng IS, Law HY, Ma ES, Xu X, Wanapirak C, Sanguansermsri T, Liao C, Ai MA, Chui DH, Cantor CR, Lo YM. MS analysis of single-nucleotide differences in circulating nucleic acids: Application to noninvasive prenatal diagnosis. Proc Natl Acad Sci U S A. 2004 Jul 20; 101(29):10762-7. PMID: 15247415.
    View in: PubMed
  49. Wang W, Ma ES, Chan AY, Prior J, Erber WN, Chan LC, Chui DH, Chong SS. Single-tube multiplex-PCR screen for anti-3.7 and anti-4.2 alpha-globin gene triplications. Clin Chem. 2003 Oct; 49(10):1679-82. PMID: 14500599.
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  50. Lafferty JD, Waye JS, Chui DH, Crawford L, Raby A, Richardson H. Good practice guidelines for laboratory investigation of hemoglobinopathies. Lab Hematol. 2003; 9(4):237-45. PMID: 14649467.
    View in: PubMed
  51. Chiu RW, Lau TK, Leung TN, Chow KC, Chui DH, Lo YM. Prenatal exclusion of beta thalassaemia major by examination of maternal plasma. Lancet. 2002 Sep 28; 360(9338):998-1000. PMID: 12383672.
    View in: PubMed
  52. Chui DH, Fucharoen S, Chan V. Hemoglobin H disease: not necessarily a benign disorder. Blood. 2003 Feb 1; 101(3):791-800. PMID: 12393486.
    View in: PubMed
  53. Hardison RC, Chui DH, Giardine B, Riemer C, Patrinos GP, Anagnou N, Miller W, Wajcman H. HbVar: A relational database of human hemoglobin variants and thalassemia mutations at the globin gene server. Hum Mutat. 2002 Mar; 19(3):225-33. PMID: 11857738.
    View in: PubMed
  54. Lorey F, Charoenkwan P, Witkowska HE, Lafferty J, Patterson M, Eng B, Waye JS, Finklestein JZ, Chui DH. Hb H hydrops foetalis syndrome: a case report and review of literature. Br J Haematol. 2001 Oct; 115(1):72-8. PMID: 11722414.
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  55. Su YY, Gordon CT, Ye TZ, Perkins AC, Chui DH. Human ERMAP: an erythroid adhesion/receptor transmembrane protein. Blood Cells Mol Dis. 2001 Sep-Oct; 27(5):938-49. PMID: 11783959.
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  56. Waye JS, Eng B, Patterson M, Walker L, Carcao MD, Olivieri NF, Chui DH. Hemoglobin H (Hb H) disease in Canada: molecular diagnosis and review of 116 cases. Am J Hematol. 2001 Sep; 68(1):11-5. PMID: 11559931.
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  57. Lau ET, Kwok YK, Chui DH, Wong HS, Luo HY, Tang MH. Embryonic and fetal globins are expressed in adult erythroid progenitor cells and in erythroid cell cultures. Prenat Diagn. 2001 Jul; 21(7):529-39. PMID: 11494285.
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  58. Chan LC, Ma SK, Chan AY, Ha SY, Waye JS, Lau YL, Chui DH. Should we screen for globin gene mutations in blood samples with mean corpuscular volume (MCV) greater than 80 fL in areas with a high prevalence of thalassaemia? J Clin Pathol. 2001 Apr; 54(4):317-20. PMID: 11304851.
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  59. Horsley SW, Daniels RJ, Anguita E, Raynham HA, Peden JF, Villegas A, Vickers MA, Green S, Waye JS, Chui DH, Ayyub H, MacCarthy AB, Buckle VJ, Gibbons RJ, Kearney L, Higgs DR. Monosomy for the most telomeric, gene-rich region of the short arm of human chromosome 16 causes minimal phenotypic effects. Eur J Hum Genet. 2001 Mar; 9(3):217-25. PMID: 11313762.
    View in: PubMed
  60. Chui DH, Dover GJ. Sickle cell disease: no longer a single gene disorder. Curr Opin Pediatr. 2001 Feb; 13(1):22-7. PMID: 11176239.
    View in: PubMed
  61. Lorey F, Cunningham G, Vichinsky EP, Lubin BH, Witkowska HE, Matsunaga A, Azimi M, Sherwin J, Eastman J, Farina F, Waye JS, Chui DH. Universal newborn screening for Hb H disease in California. Genet Test. 2001; 5(2):93-100. PMID: 11551109.
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  62. Lafferty JD, Crowther MA, Waye JS, Chui DH. A reliable screening test to identify adult carriers of the (--SEA) alpha zero-thalassemia deletion. Detection of embryonic zeta-globin chains by enzyme-linked immunosorbent assay. Am J Clin Pathol. 2000 Dec; 114(6):927-31. PMID: 11338482.
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  63. Krishnamurti L, Chui DH, Dallaire M, LeRoy B, Waye JS, Perentesis JP. Coinheritance of alpha-thalassemia-1 and hemoglobin E/beta zero-thalassemia: practical implications for neonatal screening and genetic counseling. J Pediatr. 1998 May; 132(5):863-5. PMID: 9602201.
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  64. Chui DH, Hardison R, Riemer C, Miller W, Carver MF, Molchanova TP, Efremov GD, Huisman TH. An electronic database of human hemoglobin variants on the World Wide Web. Blood. 1998 Apr 15; 91(8):2643-4. PMID: 9531571.
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  65. Chui DH, Waye JS. Hydrops fetalis caused by alpha-thalassemia: an emerging health care problem. Blood. 1998 Apr 01; 91(7):2213-22. PMID: 9516118.
    View in: PubMed
  66. Tang W, Lai YH, Han XD, Wong PM, Peters LL, Chui DH. Murine Hn1 on chromosome 11 is expressed in hemopoietic and brain tissues. Mamm Genome. 1997 Sep; 8(9):695-6. PMID: 9271675.
    View in: PubMed
  67. Lau YL, Chan LC, Chan YY, Ha SY, Yeung CY, Waye JS, Chui DH. Prevalence and genotypes of alpha- and beta-thalassemia carriers in Hong Kong -- implications for population screening. N Engl J Med. 1997 May 01; 336(18):1298-301. PMID: 9113933.
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  68. Luo HY, Deisseroth AB, Chui DH. Human embryonic zeta-globin gene expression in mouse-human hybrid erythroid cell lines. Blood. 1995 Aug 01; 86(3):1212-7. PMID: 7620174.
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  69. Chui DH, Tang W, Orkin SH. cDNA cloning of murine Nrf 2 gene, coding for a p45 NF-E2 related transcription factor. Biochem Biophys Res Commun. 1995 Apr 06; 209(1):40-6. PMID: 7726861.
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  70. Tang W, Luo HY, Eng B, Waye JS, Chui DH. Immunocytological test to detect adult carriers of (--SEA/) deletional alpha-thalassaemia. Lancet. 1993 Nov 06; 342(8880):1145-7. PMID: 7901477.
    View in: PubMed
  71. Waye JS, Eng B, Cai SP, Patterson M, Smith J, Tang W, Chui DH. Carrier detection and prenatal diagnosis of hemoglobinopathies in Ontario. Clin Invest Med. 1993 Oct; 16(5):358-71. PMID: 8261689.
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  72. Tang W, Cai SP, Eng B, Poon MC, Waye JS, Illum N, Chui DH. Expression of embryonic zeta-globin and epsilon-globin chains in a 10-year-old girl with congenital anemia. Blood. 1993 Mar 15; 81(6):1636-40. PMID: 7680924.
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  73. Tang W, Luo HY, Albitar M, Patterson M, Eng B, Waye JS, Liebhaber SA, Higgs DR, Chui DH. Human embryonic zeta-globin chain expression in deletional alpha-thalassemias. Blood. 1992 Jul 15; 80(2):517-22. PMID: 1627804.
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  74. Waye JS, Eng B, Chui DH. Identification of an extensive zeta-alpha globin gene deletion in a Chinese individual. Br J Haematol. 1992 Mar; 80(3):378-80. PMID: 1581218.
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  75. Chui DH, Patterson M, Dowling CE, Kazazian HH, Kendall AG. Hemoglobin Bart's disease in an Italian boy. Interaction between alpha-thalassemia and hereditary persistence of fetal hemoglobin. N Engl J Med. 1990 Jul 19; 323(3):179-82. PMID: 1694572.
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  76. Toles JF, Chui DH, Belbeck LW, Starr E, Barker JE. Hemopoietic stem cells in murine embryonic yolk sac and peripheral blood. Proc Natl Acad Sci U S A. 1989 Oct; 86(19):7456-9. PMID: 2571992.
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  77. Chui DH, Mentzer WC, Patterson M, Iarocci TA, Embury SH, Perrine SP, Mibashan RS, Higgs DR. Human embryonic zeta-globin chains in fetal and newborn blood. Blood. 1989 Sep; 74(4):1409-14. PMID: 2475189.
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  78. Luo HY, Clarke BJ, Gauldie J, Patterson M, Liao SK, Chui DH. A novel monoclonal antibody based diagnostic test for alpha-thalassemia-1 carriers due to the (-SEA/) deletion. Blood. 1988 Nov; 72(5):1589-94. PMID: 3179441.
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  79. Zhao JQ, Luo HY, Clarke BJ, Chui DH. An immunoassay to detect human embryonic epsilon globin chains by a murine monoclonal antibody. Blood. 1988 Apr; 71(4):883-7. PMID: 3162692.
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  80. Wong PM, Chung SW, Chui DH, Eaves CJ. Properties of the earliest clonogenic hemopoietic precursors to appear in the developing murine yolk sac. Proc Natl Acad Sci U S A. 1986 Jun; 83(11):3851-4. PMID: 3012535.
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  81. Wong PM, Chung SW, Reicheld SM, Chui DH. Hemoglobin switching during murine embryonic development: evidence for two populations of embryonic erythropoietic progenitor cells. Blood. 1986 Mar; 67(3):716-21. PMID: 3947744.
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  82. Chui DH, Wong SC, Chung SW, Patterson M, Bhargava S, Poon MC. Embryonic zeta-globin chains in adults: a marker for alpha-thalassemia-1 haplotype due to a greater than 17.5-kb deletion. N Engl J Med. 1986 Jan 09; 314(2):76-9. PMID: 3941693.
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  83. Chung SW, Wong SC, Clarke BJ, Patterson M, Walker WH, Chui DH. Human embryonic zeta-globin chains in adult patients with alpha-thalassemias. Proc Natl Acad Sci U S A. 1984 Oct; 81(19):6188-91. PMID: 6592610.
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  84. Chui DH, Clarke BJ. Abnormal erythroid progenitor cells in human preleukemia. Blood. 1982 Aug; 60(2):362-7. PMID: 6980031.
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  85. Wong PM, Clarke BJ, Carr DH, Chui DH. Adult hemoglobins are synthesized in erythroid colonies in vitro derived from murine circulating hemopoietic progenitor cells during embryonic development. Proc Natl Acad Sci U S A. 1982 May; 79(9):2952-6. PMID: 6953440.
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  86. Chui DH, Wong SC, Enkin MW, Patterson M, Ives RA. Proportion of fetal hemoglobin synthesis decreases during erythroid cell maturation. Proc Natl Acad Sci U S A. 1980 May; 77(5):2757-61. PMID: 6156456.
    View in: PubMed
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