David Chui | Profiles RNS

David Hing-Kwei Chui, MD

Emeritus Professor

Boston University Chobanian & Avedisian School of Medicine

Medicine

Hematology & Medical Oncology

MD, McGill University
BSc, University of Maryland

Websites

	Boston Medical Center Provider Profile
	American Society for Clinical investigation Profile

ORCID : 0000-0002-1475-7309

Dr. Chui is a physician-scientist with a long standing clinical and research interest in hemoglobin disorders. He has contributed to the field ranging from population genetics, genotype-phenotype correlation, genetic modifiers, and regulation of HbF expression. He received MD,CM degree from McGill University, Montreal, Canada in 1963. In 1970, he joined the Faculty at the McMaster University, Hamilton, Ontario, Canada, and rose to become a full Professor in 1982. He has always enjoyed teaching and mentoring students, residents and fellows. He served on the Editorial Board of BLOOD (1980-84), American Society of Hematology (ASH) Committee on Educational Affairs and Training (1984-87), NIH Hematology Study Section (1987-91), ASH Scientific Affairs Subcommittee on Hemoglobin/Red Cell (1989-1991), and Chair of Medical Advisory Board, the Thalassemia Foundation of Canada (2000-2002). He was elected to two honorific societies, the American Society for Clinical Investigation (1980) and the Association of American Physicians (1991). In 2003, Dr. Chui joined Chobanian and Avedisian School of Medicine, and was appointed a full Professor of Medicine, Pathology and Laboratory Medicine.

Expertise includes: Globin gene mutations; Hemoglobin diseases; Thalassmeias; and Regulation of fetal hemoglobin expression.

Member
Boston University
Center for Regenerative Medicine

Member
Boston University
Center of Excellence in Sickle Cell Disease

Member
Boston University
Evans Center for Interdisciplinary Biomedical Research

Globin Gene Expression in Sickle Cell Genotype-Specific iPS cells
07/05/2011 - 06/30/2017 (Multi-PI)
PI: David Hing-Kwei Chui, MD
NIH/National Heart, Lung, and Blood Institute
5U01HL107443-05

Globin Gene Expression in Sickle Cell Genotype-Specific iPS cells
07/05/2011 - 06/30/2016 (Co-Investigator)
PI: Martin H. Steinberg, MD
NIH/National Heart, Lung, and Blood Institute
1U01HL107443-01

Sickle Cell - Research Scholar
04/01/2003 - 03/31/2008 (PI)
NIH-NHLBI
5 U54 HL070819-05 (A)

Title

Yr	Title	Project-Sub Proj	Pubs
2015	Globin Gene Expression in Sickle Cell Genotype-Specific iPS cells	5U01HL107443-05	16
2014	Globin Gene Expression in Sickle Cell Genotype-Specific iPS cells	5U01HL107443-04	16
2013	Globin Gene Expression in Sickle Cell Genotype-Specific iPS cells	5U01HL107443-03	16
2012	Globin Gene Expression in Sickle Cell Genotype-Specific iPS cells	5U01HL107443-02	16
2011	Globin Gene Expression in Sickle Cell Genotype-Specific iPS cells	1U01HL107443-01	16
2009	Genetic Modulation of HbF in Beta Thalassemia	5R01DK069646-05	16
2008	AUTOMATED ID OF PROTEINS, VARIANTS &POST-TRANSLATIONAL MODIFICATIONS	5P41RR010888-12-5180	259
2008	Genetic Modulation of HbF in Beta Thalassemia	5R01DK069646-04	16
2007	AUTOMATED ID OF PROTEINS, VARIANTS &POST-TRANSLATIONAL MODIFICATIONS	2P41RR010888-11-8001	259
2007	Genetic Modulation of HbF in Beta Thalassemia	5R01DK069646-03	16

Showing 10 of 15 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Sun Y, Habara A, Le CQ, Nguyen N, Chen R, Murphy GJ, Chui DHK, Steinberg MH, Cui S. Pharmacologic induction of PGC-1a stimulates fetal haemoglobin gene expression. Br J Haematol. 2022 Apr; 197(1):97-109.View Related Profiles.

Le, Cuong
Chui, David
Murphy, George
Steinberg, Martin
Cui, Shuaiying

PMID: 35118652

Aygun B, Bello A, Thompson AA, Davis L, Sun Y, Luo HY, Cui S, Chui DHK. Clinical phenotypes of three children with sickle cell disease caused by HbS/Sicilian (dß)0 -thalassemia deletion. Am J Hematol. 2022 04; 97(4):E156-E158.View Related Profiles.

Chui, David
Cui, Shuaiying

PMID: 35045200; DOI: 10.1002/ajh.26470;

Patrinos GP, Chui DHK, Hardison RC, Steinberg MH. Strategies to improve pharmacogenomic-guided treatment options for patients with ß-hemoglobinopathies. Expert Rev Hematol. 2021 10; 14(10):883-885.View Related Profiles.

Chui, David
Steinberg, Martin

PMID: 34490838; PMCID: PMC9306350; DOI: 10.1080/17474086.2021.1977117;

Atroshi SD, Al-Allawi N, Chui DHK, Najmabadi H, Khailany RA. A Novel ß0-Thalassemia Mutation, HBB: c.356_357delTT [Codon 118 (-TT)] in an Iraqi Kurd. Hemoglobin. 2021 May; 45(3):212-214. PMID: 34167424; DOI: 10.1080/03630269.2021.1941082;

Harris NS, Kavesh M, Beal SG, Winter WE, Chui DHK. When Hemoglobin Reported to Be A, S, and F Are Neither A, S, Nor F: A Tale of Two Patients. J Appl Lab Med. 2021 03 01; 6(2):543-549. PMID: 32995874; DOI: 10.1093/jalm/jfaa087;

Solano-Vargas M, Chui DHK, Rodriguez-Romero W. Alpha-thalassemia. Case report alpha-thalassemia in a Costa Rican family, A case report. Clin Case Rep. 2021 Jan; 9(1):291-293. PMID: 33489176; PMCID: PMC7813090; DOI: 10.1002/ccr3.3518;

Dai Y, Shaikho EM, Perez J, Wilson CA, Liu LY, White MR, Farrell JJ, Chui DHK, Sebastiani P, Steinberg MH. BCL2L1 is associated with ?-globin gene expression. Blood Adv. 2019 10 22; 3(20):2995-3001.View Related Profiles.

Chui, David
Steinberg, Martin
Sebastiani, Paola
Dai, Yan

PMID: 31648320; PMCID: PMC6849934; DOI: 10.1182/bloodadvances.2019032243;

Homsy E, Alghothani L, Chui DHK, Sood N. An Unusual Case of Low Hemoglobin Oxygen Saturation. Ann Am Thorac Soc. 2019 06; 16(6):756-759. PMID: 31149860; DOI: 10.1513/AnnalsATS.201811-829CC;

Le CQ, Myers G, Habara A, Jearawiriyapaisarn N, Murphy GJ, Chui DHK, Steinberg MH, Engel JD, Cui S. Inhibition of LSD1 by small molecule inhibitors stimulates fetal hemoglobin synthesis. Blood. 2019 05 30; 133(22):2455-2459.View Related Profiles.

Le, Cuong
Chui, David
Murphy, George
Steinberg, Martin
Cui, Shuaiying

PMID: 30992270; PMCID: PMC6543516; DOI: 10.1182/blood.2018892737;

Xu S, Luk K, Yao Q, Shen AH, Zeng J, Wu Y, Luo HY, Brendel C, Pinello L, Chui DHK, Wolfe SA, Bauer DE. Editing aberrant splice sites efficiently restores ß-globin expression in ß-thalassemia. Blood. 2019 05 23; 133(21):2255-2262. PMID: 30704988; PMCID: PMC6533605; DOI: 10.1182/blood-2019-01-895094;

Showing 10 of 136 results. Show More

Al-Allawi N, Qadir SMA, Puehringer H, Chui DHK, Farrell JJ, Oberkanins C. The association of HBG2, BCL11A, and HMIP polymorphisms with fetal hemoglobin and clinical phenotype in Iraqi Kurds with sickle cell disease. Int J Lab Hematol. 2019 Feb; 41(1):87-93. PMID: 30216683; DOI: 10.1111/ijlh.12927;

Vanuytsel K, Matte T, Leung A, Naing ZH, Morrison T, Chui DHK, Steinberg MH, Murphy GJ. Induced pluripotent stem cell-based mapping of ß-globin expression throughout human erythropoietic development. Blood Adv. 2018 08 14; 2(15):1998-2011.View Related Profiles.

Chui, David
Murphy, George
Vanuytsel, Kim
Steinberg, Martin

PMID: 30108108; PMCID: PMC6093724; DOI: 10.1182/bloodadvances.2018020560;

Kim JT, Winter WE, Luo HY, Chui DHK, Harris NS. Interference of Hemoglobin A1c Due to Hemoglobin Franklin Park. J Appl Lab Med. 2019 03; 3(5):911-913. PMID: 31639767; DOI: 10.1373/jalm.2018.026781;

Singh SA, Sarangi S, Appiah-Kubi A, Hsu P, Smith WB, Gallagher PG, Glader B, Chui DHK. Hb Adana (HBA2 or HBA1: c.179G > A) and alpha thalassemia: Genotype-phenotype correlation. Pediatr Blood Cancer. 2018 09; 65(9):e27220. PMID: 29749692

Akinbami AO, Sobota AE, Luo HY, Chui DHK, Steinberg MH. A Mild Phenotype of Severe ß+ Thalassemia in a 16-Month-Old Boy. J Pediatr Hematol Oncol. 2018 04; 40(3):e145-e147.View Related Profiles.

Sobota, Amy
Chui, David
Steinberg, Martin

PMID: 29309373

Leung A, Zulick E, Skvir N, Vanuytsel K, Morrison TA, Naing ZH, Wang Z, Dai Y, Chui DHK, Steinberg MH, Sherr DH, Murphy GJ. Notch and Aryl Hydrocarbon Receptor Signaling Impact Definitive Hematopoiesis from Human Pluripotent Stem Cells. Stem Cells. 2018 07; 36(7):1004-1019.View Related Profiles.

Sherr, David
Chui, David
Murphy, George
Vanuytsel, Kim
Steinberg, Martin
Morrison, Tasha
Dai, Yan
Wang, Zhongyan

PMID: 29569827; PMCID: PMC6099224; DOI: 10.1002/stem.2822;

Morrison TA, Wilcox I, Luo HY, Farrell JJ, Kurita R, Nakamura Y, Murphy GJ, Cui S, Steinberg MH, Chui DHK. A long noncoding RNA from the HBS1L-MYB intergenic region on chr6q23 regulates human fetal hemoglobin expression. Blood Cells Mol Dis. 2018 03; 69:1-9.View Related Profiles.

Chui, David
Murphy, George
Luo, Hong
Steinberg, Martin
Cui, Shuaiying
Morrison, Tasha

PMID: 29227829; PMCID: PMC5783741; DOI: 10.1016/j.bcmd.2017.11.003;

Shaikho EM, Farrell JJ, Alsultan A, Qutub H, Al-Ali AK, Figueiredo MS, Chui DHK, Farrer LA, Murphy GJ, Mostoslavsky G, Sebastiani P, Steinberg MH. A phased SNP-based classification of sickle cell anemia HBB haplotypes. BMC Genomics. 2017 Aug 11; 18(1):608.View Related Profiles.

Chui, David
Murphy, George
Mostoslavsky, Gustavo
Farrer, Lindsay
Steinberg, Martin
Sebastiani, Paola

PMID: 28800727; PMCID: PMC5553663; DOI: 10.1186/s12864-017-4013-y;

Cancio MI, Aygun B, Chui DHK, Rothman JA, Scott JP, Estepp JH, Hankins JS. The clinical severity of hemoglobin S/Black (A ?dß)0 -thalassemia. Pediatr Blood Cancer. 2017 Nov; 64(11). PMID: 28453928; PMCID: PMC6615052; DOI: 10.1002/pbc.26596;

Pernudy-Ubau A, Salinas-Molina J, Requenez Y, Ortiz-Lopez M, Puller AC, García-Rosales K, Rodríguez-Estrada A, Rodríguez-Romero W, Mejía-Baltodano G, Luo HY, Chui DHK. Hb Presbyterian (HBB: c.327C>G) in a Nicaraguan Family. Hemoglobin. 2017 Jan; 41(1):50-52. PMID: 28395541

Jiang Z, Luo HY, Farrell JJ, Zhang Z, Schulz VP, Albarawi D, Steinberg MH, Al-Allawi NAS, Gallagher PG, Forget BG, Chui DHK. A variant Sp1 (R218Q) transcription factor might enhance HbF expression in ß0 -thalassaemia homozygotes. Br J Haematol. 2018 03; 180(5):755-757.View Related Profiles.

Chui, David
Luo, Hong
Steinberg, Martin
Jiang, Zhihua

PMID: 28240767; DOI: 10.1111/bjh.14445;

Park S, Gianotti-Sommer A, Molina-Estevez FJ, Vanuytsel K, Skvir N, Leung A, Rozelle SS, Shaikho EM, Weir I, Jiang Z, Luo HY, Chui DHK, Figueiredo MS, Alsultan A, Al-Ali A, Sebastiani P, Steinberg MH, Mostoslavsky G, Murphy GJ. A Comprehensive, Ethnically Diverse Library of Sickle Cell Disease-Specific Induced Pluripotent Stem Cells. Stem Cell Reports. 2017 Apr 11; 8(4):1076-1085.View Related Profiles.

Chui, David
Murphy, George
Mostoslavsky, Gustavo
Luo, Hong
Vanuytsel, Kim
Steinberg, Martin
Sebastiani, Paola
Jiang, Zhihua

PMID: 28111279; PMCID: PMC5390092; DOI: 10.1016/j.stemcr.2016.12.017;

Vathipadiekal V, Farrell JJ, Wang S, Edward HL, Shappell H, Al-Rubaish AM, Al-Muhanna F, Naserullah Z, Alsuliman A, Qutub HO, Simkin I, Farrer LA, Jiang Z, Luo HY, Huang S, Mostoslavsky G, Murphy GJ, Patra PK, Chui DH, Alsultan A, Al-Ali AK, Sebastiani P, Steinberg MH. A candidate transacting modulator of fetal hemoglobin gene expression in the Arab-Indian haplotype of sickle cell anemia. Am J Hematol. 2016 Nov; 91(11):1118-1122.View Related Profiles.

Chui, David
Murphy, George
Mostoslavsky, Gustavo
Luo, Hong
Farrer, Lindsay
Steinberg, Martin
Sebastiani, Paola
Vathipadiekal, Vinod
Jiang, Zhihua

PMID: 27501013; PMCID: PMC5072989; DOI: 10.1002/ajh.24527;

Boucher MO, Chui DH, Woda BA, Newburger PE. Mild Microcytic Anemia in an Infant with a Compound Heterozygosity for Hb C (HBB: c.19G?>?A) and Hb Osu Christiansborg (HBB: c.157G?>?A). Hemoglobin. 2016 Jun; 40(3):208-9. PMID: 27117572; DOI: 10.3109/03630269.2016.1165245;

Vathipadiekal V, Alsultan A, Baltrusaitis K, Farrell JJ, Al-Rubaish AM, Al-Muhanna F, Naserullah Z, Suliman A, Patra PK, Milton JN, Farrer LA, Chui DH, Al-Ali AK, Sebastiani P, Steinberg MH. Homozygosity for a haplotype in the HBG2-OR51B4 region is exclusive to Arab-Indian haplotype sickle cell anemia. Am J Hematol. 2016 06; 91(6):E308-11.View Related Profiles.

Chui, David
Hicks, Jacqueline
Farrer, Lindsay
Steinberg, Martin
Sebastiani, Paola
Vathipadiekal, Vinod

PMID: 27185208; PMCID: PMC4874527; DOI: 10.1002/ajh.24368;

Luo HY, Chui DH. Diverse hematological phenotypes of ß-thalassemia carriers. Ann N Y Acad Sci. 2016 Mar; 1368(1):49-55.View Related Profiles.

Chui, David
Luo, Hong

PMID: 27123947; DOI: 10.1111/nyas.13056;

Shaikho EM, Habara AH, Alsultan A, Al-Rubaish AM, Al-Muhanna F, Naserullah Z, Alsuliman A, Qutub HO, Patra PK, Sebastiani P, Baltrusaitis K, Farrell JJ, Jiang Z, Luo HY, Chui DH, Al-Ali AK, Steinberg MH. Variants of ZBTB7A (LRF) and its ß-globin gene cluster binding motifs in sickle cell anemia. Blood Cells Mol Dis. 2016 07; 59:49-51.View Related Profiles.

Chui, David
Luo, Hong
Steinberg, Martin
Sebastiani, Paola
Jiang, Zhihua

PMID: 27282567; PMCID: PMC6733020; DOI: 10.1016/j.bcmd.2016.04.001;

Jiang Z, Luo HY, Huang S, Farrell JJ, Davis L, Théberge R, Benson KA, Riolueang S, Viprakasit V, Al-Allawi NA, Ünal S, Gümrük F, Akar N, Basak AN, Osorio L, Badens C, Pissard S, Joly P, Campbell AD, Gallagher PG, Steinberg MH, Forget BG, Chui DH. The genetic basis of asymptomatic codon 8 frame-shift (HBB:c25_26delAA) ß(0) -thalassaemia homozygotes. Br J Haematol. 2016 Mar; 172(6):958-65.View Related Profiles.

Chui, David
Luo, Hong
Benson, Katherine
Steinberg, Martin
Theberge, Roger
Jiang, Zhihua

PMID: 26771086; DOI: 10.1111/bjh.13909;

Dai Y, Sangerman J, Luo HY, Fucharoen S, Chui DH, Faller DV, Perrine SP. Therapeutic fetal-globin inducers reduce transcriptional repression in hemoglobinopathy erythroid progenitors through distinct mechanisms. Blood Cells Mol Dis. 2016 Jan; 56(1):62-9.View Related Profiles.

Chui, David
Faller, Douglas
Luo, Hong
Perrine-Faller, Susan
Dai, Yan

PMID: 26603726; PMCID: PMC4667977; DOI: 10.1016/j.bcmd.2015.10.004;

Akinbami AO, Campbell AD, Han ZJ, Luo HY, Chui DH, Steinberg MH. Hereditary Persistence of Fetal Hemoglobin Caused by Single Nucleotide Promoter Mutations in Sickle Cell Trait and Hb SC Disease. Hemoglobin. 2016; 40(1):64-5.View Related Profiles.

Chui, David
Luo, Hong
Steinberg, Martin

PMID: 26372199; DOI: 10.3109/03630269.2015.1080725;

Théberge R, Dikler S, Heckendorf C, Chui DH, Costello CE, McComb ME. MALDI-ISD Mass Spectrometry Analysis of Hemoglobin Variants: a Top-Down Approach to the Characterization of Hemoglobinopathies. J Am Soc Mass Spectrom. 2015 Aug; 26(8):1299-310.View Related Profiles.

Costello, Catherine
Chui, David
McComb, Mark
Theberge, Roger

PMID: 26002792; PMCID: PMC4496427; DOI: 10.1007/s13361-015-1164-4;

Unal S, Chui DH, Gumruk F. Fanconi's Anemia Effect or Sickle Cell Anemia Effect: That is the Question. Hemoglobin. 2015; 39(4):287-9. PMID: 25976779; DOI: 10.3109/03630269.2015.1041036;

Sebastiani P, Farrell JJ, Alsultan A, Wang S, Edward HL, Shappell H, Bae H, Milton JN, Baldwin CT, Al-Rubaish AM, Naserullah Z, Al-Muhanna F, Alsuliman A, Patra PK, Farrer LA, Ngo D, Vathipadiekal V, Chui DH, Al-Ali AK, Steinberg MH. BCL11A enhancer haplotypes and fetal hemoglobin in sickle cell anemia. Blood Cells Mol Dis. 2015 Mar; 54(3):224-30.View Related Profiles.

Chui, David
Ngo, Doan
Ngo, Duyen
Hicks, Jacqueline
Farrer, Lindsay
Steinberg, Martin
Sebastiani, Paola
Vathipadiekal, Vinod

PMID: 25703683; PMCID: PMC4341902; DOI: 10.1016/j.bcmd.2015.01.001;

Unal S, Chui DH, Luo HY, Okur H, Oymak Y, Gumruk F. The first report of a homozygous codons 9/10 (+T) ß-thalassemia mutation in a Turkish patient. Hemoglobin. 2015; 39(1):66-8. PMID: 25572182; DOI: 10.3109/03630269.2014.982255;

Edward HL, Pisani LA, Rodriguez-Romero WE, Chaves-Villalobos J, Garcia-Quesada J, Harris NS, Luo HY, Steinberg MH, Forget BG, Chui DH. Hb Youngstown [ß101(G3)Glu???Ala; HBB: c.305A > C]: An unstable hemoglobin variant causing severe hemolytic anemia. Hemoglobin. 2014; 38(6):381-4.View Related Profiles.

Chui, David
Luo, Hong
Steinberg, Martin

PMID: 25347256; DOI: 10.3109/03630269.2014.971960;

Griffin PJ, Sebastiani P, Edward H, Baldwin CT, Gladwin MT, Gordeuk VR, Chui DH, Steinberg MH. The genetics of hemoglobin A2 regulation in sickle cell anemia. Am J Hematol. 2014 Nov; 89(11):1019-23.View Related Profiles.

Chui, David
Steinberg, Martin
Sebastiani, Paola

PMID: 25042611; PMCID: PMC4298130; DOI: 10.1002/ajh.23811;

Patthamalai P, Fuchareon S, Chaneiam N, Ghalie RG, Chui DH, Boosalis MS, Perrine SP. A phase 2 trial of HQK-1001 in HbE-ß thalassemia demonstrates HbF induction and reduced anemia. Blood. 2014 Mar 20; 123(12):1956-7.View Related Profiles.

Chui, David
Perrine-Faller, Susan

PMID: 24652964; PMCID: PMC3962168; DOI: 10.1182/blood-2013-11-538470;

Steinberg MH, Chui DH. HbC disorders. Blood. 2013 Nov 21; 122(22):3698.View Related Profiles.

Chui, David
Steinberg, Martin

PMID: 24263962; DOI: 10.1182/blood-2013-09-526764;

Inati A, Kahale M, Perrine SP, Chui DH, Taher AT, Koussa S, Abi Nasr T, Abbas HA, Ghalie RG. A phase 2 study of HQK-1001, an oral fetal haemoglobin inducer, in ß-thalassaemia intermedia. Br J Haematol. 2014 Feb; 164(3):456-8.View Related Profiles.

Chui, David
Perrine-Faller, Susan

PMID: 24224649; PMCID: PMC3904791; DOI: 10.1111/bjh.12635;

Alsultan A, Alabdulaali MK, Griffin PJ, Alsuliman AM, Ghabbour HA, Sebastiani P, Albuali WH, Al-Ali AK, Chui DH, Steinberg MH. Sickle cell disease in Saudi Arabia: the phenotype in adults with the Arab-Indian haplotype is not benign. Br J Haematol. 2014 Feb; 164(4):597-604.View Related Profiles.

Chui, David
Steinberg, Martin
Sebastiani, Paola

PMID: 24224700; PMCID: PMC4094128; DOI: 10.1111/bjh.12650;

Steinberg MH, Chui DH, Dover GJ, Sebastiani P, Alsultan A. Fetal hemoglobin in sickle cell anemia: a glass half full? Blood. 2014 Jan 23; 123(4):481-5.View Related Profiles.

Chui, David
Steinberg, Martin
Sebastiani, Paola

PMID: 24222332; DOI: 10.1182/blood-2013-09-528067;

Shi Y, Kulbacki E, Chui DH, Wang E. Gigantic splenomegaly in a 27-year-old male of South-East Asian descent with concurrent diagnosis of myeloproliferative neoplasm and hemoglobin H disease. Eur J Haematol. 2013 Sep; 91(3):284-5. PMID: 23672282; DOI: 10.1111/ejh.12137;

Croteau SE, Luo HY, Lehmann LE, Chui DH, Neufeld EJ. Novel dominant ß-thalassemia: Hb Boston-Kuwait [codon 139/140(+T)]. Pediatr Blood Cancer. 2013 Oct; 60(10):E131-4.View Related Profiles.

Chui, David
Luo, Hong

PMID: 23776097; DOI: 10.1002/pbc.24611;

Smith BW, Rozelle SS, Leung A, Ubellacker J, Parks A, Nah SK, French D, Gadue P, Monti S, Chui DH, Steinberg MH, Frelinger AL, Michelson AD, Theberge R, McComb ME, Costello CE, Kotton DN, Mostoslavsky G, Sherr DH, Murphy GJ. The aryl hydrocarbon receptor directs hematopoietic progenitor cell expansion and differentiation. Blood. 2013 Jul 18; 122(3):376-85.View Related Profiles.

Leung, Amy
Costello, Catherine
Kotton, Darrell
Sherr, David
Chui, David
Murphy, George
Mostoslavsky, Gustavo
McComb, Mark
Steinberg, Martin
Theberge, Roger
Monti, Stefano

PMID: 23723449; PMCID: PMC3716202; DOI: 10.1182/blood-2012-11-466722;

Alsultan A, Ngo D, Bae H, Sebastiani P, Baldwin CT, Melista E, Suliman AM, Albuali WH, Nasserullah Z, Luo HY, Chui DH, Steinberg MH, Al-Ali AK. Genetic studies of fetal hemoglobin in the Arab-Indian haplotype sickle cell-ß(0) thalassemia. Am J Hematol. 2013 Jun; 88(6):531-2.View Related Profiles.

Baldwin, Clinton
Chui, David
Ngo, Duyen
Steinberg, Martin
Sebastiani, Paola

PMID: 23483609; DOI: 10.1002/ajh.23434;

Ngo D, Bae H, Steinberg MH, Sebastiani P, Solovieff N, Baldwin CT, Melista E, Safaya S, Farrer LA, Al-Suliman AM, Albuali WH, Al Bagshi MH, Naserullah Z, Akinsheye I, Gallagher P, Luo HY, Chui DH, Farrell JJ, Al-Ali AK, Alsultan A. Fetal hemoglobin in sickle cell anemia: genetic studies of the Arab-Indian haplotype. Blood Cells Mol Dis. 2013 Jun; 51(1):22-6.View Related Profiles.

Baldwin, Clinton
Chui, David
Ngo, Duyen
Luo, Hong
Farrer, Lindsay
Steinberg, Martin
Sebastiani, Paola

PMID: 23465615; PMCID: PMC3647015; DOI: 10.1016/j.bcmd.2012.12.005;

Marks A, Luo HY, Chui DH, Greenberg J. Hemoglobin Shady Grove: a novel fetal methemoglobin variant. Pediatr Blood Cancer. 2013 Aug; 60(8):E55-6. PMID: 23460588; DOI: 10.1002/pbc.24503;

Inati A, Abbas HA, Al-Danaf J, Souaid M, Kahale M, Koussa S, Abou Nasr T, Davis L, Luo HY, Chui DH. Identification of the first mutation in a BRE motif of the ß-globin gene and its inheritance with two other a-globin gene mutations in a Lebanese family. Hemoglobin. 2013; 37(2):171-5. PMID: 23470150; DOI: 10.3109/03630269.2013.772523;

Whyte D, Forget B, Chui DH, Luo HY, Pashankar F. Massive splenic infarction in an adolescent with hemoglobin S-HPFH. Pediatr Blood Cancer. 2013 Jul; 60(7):E49-51. PMID: 23281181; DOI: 10.1002/pbc.24444;

Verhovsek MM, Chui DH. Pulse oximetry screening for critical congenital heart defects. Lancet. 2012 Oct 13; 380(9850):1305-6; author reply 1306. PMID: 23063278; DOI: 10.1016/S0140-6736(12)61754-1;

Alsultan A, Ngo DA, Farrell JJ, Akinsheye I, Solovieff N, Ghabbour HA, Al-Ali A, Alsuliman A, Al-Baghshi M, Albu-Ali W, Alabdulaali M, Baldwin CT, Farrer LA, Luo H, Melista E, Safaya S, Nwaru M, Chui DH, Steinberg MH. A functional promoter polymorphism of the d-globin gene is a specific marker of the Arab-Indian haplotype. Am J Hematol. 2012 Aug; 87(8):824-6.View Related Profiles.

Baldwin, Clinton
Chui, David
Ngo, Duyen
Farrer, Lindsay
Steinberg, Martin

PMID: 22641479; DOI: 10.1002/ajh.23239;

Han ZJ, Lapuz C, Rovenger JF, Dreyfus PA, Vispo BG, Ou CN, Luo HY, Chui DH, Gallivan MV. Compound heterozygosity for Hb S [ß6(A3)Glu?Val] and Hb Kenya (A?81Leu-ß86Ala) in a Ugandan woman. Hemoglobin. 2012; 36(3):270-5. PMID: 22384817; DOI: 10.3109/03630269.2012.658483;

Verhovsek M, Shah NR, Wilcox I, Koenig SC, Barros T, Thornburg CD, Steinberg MH, Luo HY, Chui DH. Severe fetal and neonatal hemolytic anemia due to a 198 kb deletion removing the complete ß-globin gene cluster. Pediatr Blood Cancer. 2012 Nov; 59(5):941-4.View Related Profiles.

Chui, David
Luo, Hong
Steinberg, Martin

PMID: 22294483; DOI: 10.1002/pbc.24094;

Jiang Z, Yu N, Kuang P, Chen M, Shao F, Martin G, Chui DH, Cardoso WV, Ai X, Lü J. Trinucleotide repeat containing 6a (Tnrc6a)-mediated microRNA function is required for development of yolk sac endoderm. J Biol Chem. 2012 Feb 17; 287(8):5979-87.View Related Profiles.

Chui, David
Lu, Jining
Cardoso, Wellington
Ai, Xingbin
Jiang, Zhihua

PMID: 22187428; PMCID: PMC3285365; DOI: 10.1074/jbc.M111.297937;

Akinsheye I, Solovieff N, Ngo D, Malek A, Sebastiani P, Steinberg MH, Chui DH. Fetal hemoglobin in sickle cell anemia: molecular characterization of the unusually high fetal hemoglobin phenotype in African Americans. Am J Hematol. 2012 Feb; 87(2):217-9.View Related Profiles.

Malek, Anita
Chui, David
Ngo, Duyen
Steinberg, Martin
Sebastiani, Paola

PMID: 22139998; PMCID: PMC3302931; DOI: 10.1002/ajh.22221;

Verhovsek M, So CC, O'Shea T, Gibney GT, Ma ES, Steinberg MH, Chui DH. Is HbA2 level a reliable diagnostic measurement for ß-thalassemia trait in people with iron deficiency? Am J Hematol. 2012 Jan; 87(1):114-6.View Related Profiles.

Chui, David
Steinberg, Martin

PMID: 22038702; DOI: 10.1002/ajh.22188;

Ngo DA, Aygun B, Akinsheye I, Hankins JS, Bhan I, Luo HY, Steinberg MH, Chui DH. Fetal haemoglobin levels and haematological characteristics of compound heterozygotes for haemoglobin S and deletional hereditary persistence of fetal haemoglobin. Br J Haematol. 2012 Jan; 156(2):259-64.View Related Profiles.

Chui, David
Ngo, Duyen
Luo, Hong
Steinberg, Martin

PMID: 22017641; PMCID: PMC6605093; DOI: 10.1111/j.1365-2141.2011.08916.x;

Alsultan A, Solovieff N, Aleem A, AlGahtani FH, Al-Shehri A, Osman ME, Kurban K, Bahakim H, Al-Momen AK, Baldwin CT, Chui DH, Steinberg MH. Fetal hemoglobin in sickle cell anemia: Saudi patients from the Southwestern province have similar HBB haplotypes but higher HbF levels than African Americans. Am J Hematol. 2011 Jul; 86(7):612-4.View Related Profiles.

Baldwin, Clinton
Chui, David
Steinberg, Martin

PMID: 21630302; DOI: 10.1002/ajh.22032;

Akinsheye I, Alsultan A, Solovieff N, Ngo D, Baldwin CT, Sebastiani P, Chui DH, Steinberg MH. Fetal hemoglobin in sickle cell anemia. Blood. 2011 Jul 7; 118(1):19-27.View Related Profiles.

Baldwin, Clinton
Chui, David
Ngo, Duyen
Steinberg, Martin
Sebastiani, Paola

PMID: 21490337; PMCID: PMC3139383; DOI: 10.1182/blood-2011-03-325258;

Giardine B, Borg J, Higgs DR, Peterson KR, Philipsen S, Maglott D, Singleton BK, Anstee DJ, Basak AN, Clark B, Costa FC, Faustino P, Fedosyuk H, Felice AE, Francina A, Galanello R, Gallivan MV, Georgitsi M, Gibbons RJ, Giordano PC, Harteveld CL, Hoyer JD, Jarvis M, Joly P, Kanavakis E, Kollia P, Menzel S, Miller W, Moradkhani K, Old J, Papachatzopoulou A, Papadakis MN, Papadopoulos P, Pavlovic S, Perseu L, Radmilovic M, Riemer C, Satta S, Schrijver I, Stojiljkovic M, Thein SL, Traeger-Synodinos J, Tully R, Wada T, Waye JS, Wiemann C, Zukic B, Chui DH, Wajcman H, Hardison RC, Patrinos GP. Systematic documentation and analysis of human genetic variation in hemoglobinopathies using the microattribution approach. Nat Genet. 2011 Apr; 43(4):295-301. PMID: 21423179; PMCID: PMC3878152; DOI: 10.1038/ng.785;

Farrell JJ, Sherva RM, Chen ZY, Luo HY, Chu BF, Ha SY, Li CK, Lee AC, Li RC, Li CK, Yuen HL, So JC, Ma ES, Chan LC, Chan V, Sebastiani P, Farrer LA, Baldwin CT, Steinberg MH, Chui DH. A 3-bp deletion in the HBS1L-MYB intergenic region on chromosome 6q23 is associated with HbF expression. Blood. 2011 May 5; 117(18):4935-45.View Related Profiles.

Baldwin, Clinton
Chui, David
Luo, Hong
Farrer, Lindsay
Steinberg, Martin
Sebastiani, Paola
Sherva, Richard

PMID: 21385855; PMCID: PMC3100700; DOI: 10.1182/blood-2010-11-317081;

Wang W, Brugnara C, Snyder C, Wynn L, Rogers Z, Kalinyak K, Brown C, Qureshi A, Bigelow C, Neumayr L, Smith-Whitley K, Chui DH, Delahunty M, Woolson R, Steinberg M, Telen M, Kesler K. The effects of hydroxycarbamide and magnesium on haemoglobin SC disease: results of the multi-centre CHAMPS trial. Br J Haematol. 2011 Mar; 152(6):771-6.View Related Profiles.

Chui, David
Steinberg, Martin

PMID: 21275961; DOI: 10.1111/j.1365-2141.2010.08523.x;

So CC, Chan AY, Luo HY, Verhovsek M, Chui DH, Ling SC, Chan LC. Hb A2 Hong Kong - A novel d-globin variant in a Chinese family masks the diagnosis of ß-thalassemia trait. Hemoglobin. 2011; 35(2):162-5. PMID: 21417575; DOI: 10.3109/03630269.2011.557172;

Verhovsek M, Henderson MP, Cox G, Luo HY, Steinberg MH, Chui DH. Unexpectedly low pulse oximetry measurements associated with variant hemoglobins: a systematic review. Am J Hematol. 2010 Nov; 85(11):882-5.View Related Profiles.

Chui, David
Luo, Hong
Steinberg, Martin

PMID: 20890907; DOI: 10.1002/ajh.21810;

Perrine SP, Castaneda SA, Chui DH, Faller DV, Berenson RJ, Siritanaratku N, Fucharoen S. Fetal globin gene inducers: novel agents and new potential. Ann N Y Acad Sci. 2010 Aug; 1202:158-64.View Related Profiles.

Chui, David
Faller, Douglas
Castaneda, Serguei
Perrine-Faller, Susan

PMID: 20712788; PMCID: PMC3913055; DOI: 10.1111/j.1749-6632.2010.05593.x;

Phylipsen M, Harteveld CL, de Metz M, Gallivan MV, Arkesteijn SG, Luo HY, Chui DH, Giordano PC. New and known ß-thalassemia determinants masked by known and new d gene defects [Hb A(2)-Ramallah or d6(A3)Glu?Gln, GAG>>CAG]. Hemoglobin. 2010; 34(5):445-50.View Related Profiles.

Chui, David
Luo, Hong

PMID: 20854118; DOI: 10.3109/03630269.2010.511591;

Solovieff N, Milton JN, Hartley SW, Sherva R, Sebastiani P, Dworkis DA, Klings ES, Farrer LA, Garrett ME, Ashley-Koch A, Telen MJ, Fucharoen S, Ha SY, Li CK, Chui DH, Baldwin CT, Steinberg MH. Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5' olfactory receptor gene cluster. Blood. 2010 Mar 4; 115(9):1815-22.View Related Profiles.

Baldwin, Clinton
Chui, David
Klings, Elizabeth
Hicks, Jacqueline
Farrer, Lindsay
Steinberg, Martin
Sebastiani, Paola
Sherva, Richard

PMID: 20018918; PMCID: PMC2832816; DOI: 10.1182/blood-2009-08-239517;

Koenig SC, Becirevic E, Hellberg MS, Li MY, So JC, Hankins JS, Ware RE, McMahon L, Steinberg MH, Luo HY, Chui DH. Sickle cell disease caused by heterozygosity for Hb S and novel LCR deletion: Report of two patients. Am J Hematol. 2009 Sep; 84(9):603-6.View Related Profiles.

Chui, David
Luo, Hong
Steinberg, Martin

PMID: 19650141; DOI: 10.1002/ajh.21480;

Thornburg CD, Steinberg MH, Chui DH. Hemoglobin SE disease in Maine, and severe thalassemia in New Hampshire. J Pediatr Hematol Oncol. 2009 Apr; 31(4):307.View Related Profiles.

Chui, David
Steinberg, Martin

PMID: 19346889; DOI: 10.1097/MPH.0b013e31819af9db;

Chen Z, Luo HY, Steinberg MH, Chui DH. BCL11A represses HBG transcription in K562 cells. Blood Cells Mol Dis. 2009 Mar-Apr; 42(2):144-9.View Related Profiles.

Chui, David
Luo, Hong
Steinberg, Martin

PMID: 19153051; DOI: 10.1016/j.bcmd.2008.12.003;

Wilcox I, Boettger K, Greene L, Malek A, Davis L, Steinberg MH, Luo HY, Chui DH. Hemoglobin Kenya composed of alpha- and ((A)gammabeta)-fusion-globin chains, associated with hereditary persistence of fetal hemoglobin. Am J Hematol. 2009 Jan; 84(1):55-8.View Related Profiles.

Malek, Anita
Chui, David
Luo, Hong
Steinberg, Martin

PMID: 19006227; DOI: 10.1002/ajh.21308;

Zhao Z, Timofeev N, Hartley SW, Chui DH, Fucharoen S, Perls TT, Steinberg MH, Baldwin CT, Sebastiani P. Imputation of missing genotypes: an empirical evaluation of IMPUTE. BMC Genet. 2008; 9:85.View Related Profiles.

Baldwin, Clinton
Chui, David
Steinberg, Martin
Sebastiani, Paola
Perls, Thomas

PMID: 19077279; PMCID: PMC2636842; DOI: 10.1186/1471-2156-9-85;

Moradkhani K, Préhu C, Old J, Henderson S, Balamitsa V, Luo HY, Poon MC, Chui DH, Wajcman H, Patrinos GP. Mutations in the paralogous human alpha-globin genes yielding identical hemoglobin variants. Ann Hematol. 2009 Jun; 88(6):535-43.View Related Profiles.

Chui, David
Luo, Hong

PMID: 18923834; PMCID: PMC2690850; DOI: 10.1007/s00277-008-0624-3;

Sedgewick AE, Timofeev N, Sebastiani P, So JC, Ma ES, Chan LC, Fucharoen G, Fucharoen S, Barbosa CG, Vardarajan BN, Farrer LA, Baldwin CT, Steinberg MH, Chui DH. BCL11A is a major HbF quantitative trait locus in three different populations with beta-hemoglobinopathies. Blood Cells Mol Dis. 2008 Nov-Dec; 41(3):255-8.View Related Profiles.

Baldwin, Clinton
Chui, David
Farrer, Lindsay
Steinberg, Martin
Sebastiani, Paola

PMID: 18691915; PMCID: PMC4100606; DOI: 10.1016/j.bcmd.2008.06.007;

Gibney GT, Panhuysen CI, So JC, Ma ES, Ha SY, Li CK, Lee AC, Li CK, Yuen HL, Lau YL, Johnson DM, Farrell JJ, Bisbee AB, Farrer LA, Steinberg MH, Chan LC, Chui DH. Variation and heritability of Hb F and F-cells among beta-thalassemia heterozygotes in Hong Kong. Am J Hematol. 2008 Jun; 83(6):458-64.View Related Profiles.

Chui, David
Farrer, Lindsay
Steinberg, Martin

PMID: 18266208; DOI: 10.1002/ajh.21150;

Chen Z, Luo HY, Basran RK, Hsu TH, Mang DW, Nuntakarn L, Rosenfield CG, Patrinos GP, Hardison RC, Steinberg MH, Chui DH. A T-to-G transversion at nucleotide -567 upstream of HBG2 in a GATA-1 binding motif is associated with elevated hemoglobin F. Mol Cell Biol. 2008 Jul; 28(13):4386-93.View Related Profiles.

Chui, David
Luo, Hong
Steinberg, Martin
Basran, Raveen
Hsu, Tien

PMID: 18443038; PMCID: PMC2447137; DOI: 10.1128/MCB.00071-08;

Basran RK, Reiss UM, Luo HY, Ware RE, Chui DH. Beta-thalassemia intermedia due to compound heterozygosity for two beta-globin gene promoter mutations, including a novel TATA box deletion. Pediatr Blood Cancer. 2008 Feb; 50(2):363-6.View Related Profiles.

Chui, David
Luo, Hong
Basran, Raveen

PMID: 16732578

Tubman VN, Bennett CM, Luo HY, Chui DH, Heeney MM. Sickle cell disease caused by Hb S/Québec-CHORI: treatment with hydroxyurea and response. Pediatr Blood Cancer. 2007 Aug; 49(2):207-10. PMID: 17551985

Masiello D, Heeney MM, Adewoye AH, Eung SH, Luo HY, Steinberg MH, Chui DH. Hemoglobin SE disease: a concise review. Am J Hematol. 2007 Jul; 82(7):643-9.View Related Profiles.

Chui, David
Steinberg, Martin

PMID: 17278112

Waye JS, Chui DH. Hb Evora [alpha 2-35, Ser-->Pro], a novel hemoglobin variant associated with an alpha-thalassemia phenotype. Haematologica. 2007 May; 92(5):e68. PMID: 17562600

Giardine B, van Baal S, Kaimakis P, Riemer C, Miller W, Samara M, Kollia P, Anagnou NP, Chui DH, Wajcman H, Hardison RC, Patrinos GP. HbVar database of human hemoglobin variants and thalassemia mutations: 2007 update. Hum Mutat. 2007 Feb; 28(2):206. PMID: 17221864

Shinoda G, Umeda K, Heike T, Arai M, Niwa A, Ma F, Suemori H, Luo HY, Chui DH, Torii R, Shibuya M, Nakatsuji N, Nakahata T. alpha4-Integrin(+) endothelium derived from primate embryonic stem cells generates primitive and definitive hematopoietic cells. Blood. 2007 Mar 15; 109(6):2406-15. PMID: 17090646

Andersson BA, Wering ME, Luo HY, Basran RK, Steinberg MH, Smith HP, Chui DH. Sickle cell disease due to compound heterozygosity for Hb S and a novel 7.7-kb beta-globin gene deletion. Eur J Haematol. 2007 Jan; 78(1):82-5.View Related Profiles.

Chui, David
Smith, Hedy
Luo, Hong
Steinberg, Martin
Basran, Raveen

PMID: 17038017

Luo HY, Heeney M, Wang WC, Eung SH, Ware RE, Steinberg MH, Chui DH. Hemoglobinopathies mimicking Hb S/beta-thalassemia: Hb S/S with alpha-thalassemia and Hb S/Volga. Am J Hematol. 2006 May; 81(5):361-5.View Related Profiles.

Chui, David
Luo, Hong
Steinberg, Martin

PMID: 16628724

Law HY, Luo HY, Wang W, Ho JF, Najmabadi H, Ng IS, Steinberg MH, Chui DH, Chong SS. Determining the cause of patchwork HBA1 and HBA2 genes: recurrent gene conversion or crossing over fixation events. Haematologica. 2006 Mar; 91(3):297-302.View Related Profiles.

Chui, David
Steinberg, Martin

PMID: 16503550

Luo HY, Tang W, Eung SH, Coad JE, Canfield P, Keller F, Crowell EH, Steinberg MH, Chui DH. Dominantly inherited beta thalassaemia intermedia caused by a new single nucleotide deletion in exon 2 of the beta globin gene: Hb morgantown (beta91 CTG>CG). J Clin Pathol. 2005 Oct; 58(10):1110-2.View Related Profiles.

Chui, David
Luo, Hong
Steinberg, Martin

PMID: 16189162; PMCID: PMC1770750; DOI: 10.1136/jcp.2004.023010;

Luo HY, Boudreaux J, Steinberg MH, Chui DH. Patients with thalassemia in the United States. Blood. 2005 Jun 15; 105(12):4896-7.View Related Profiles.

Chui, David
Steinberg, Martin

PMID: 15933066; PMCID: PMC1894999; DOI: 10.1182/blood-2005-03-0856;

Chui DH. Alpha-thalassaemia and population health in Southeast Asia. Ann Hum Biol. 2005 Mar-Apr; 32(2):123-30. PMID: 16096207

Lau ET, Kwok YK, Luo HY, Leung KY, Lee CP, Lam YH, Chui DH, Tang MH. Simple non-invasive prenatal detection of Hb Bart's disease by analysis of fetal erythrocytes in maternal blood. Prenat Diagn. 2005 Feb; 25(2):123-8. PMID: 15712347

Chui DH. Alpha-thalassemia: Hb H disease and Hb Barts hydrops fetalis. Ann N Y Acad Sci. 2005; 1054:25-32. PMID: 16339648

Basran RK, Patterson M, Walker L, Nakamura LM, Eng B, Chui DH, Waye JS. Prenatal diagnosis of hemoglobinopathies in Ontario, Canada. Ann N Y Acad Sci. 2005; 1054:507-10.View Related Profiles.

Chui, David
Basran, Raveen

PMID: 16339708

Luo HY, Adewoye AH, Eung SH, Skelton TP, Quillen K, McMahon L, Steinberg MH, Chui DH. A novel sickle hemoglobin: hemoglobin S-south end. J Pediatr Hematol Oncol. 2004 Nov; 26(11):773-6.View Related Profiles.

Chui, David
Luo, Hong
Quillen, Karen
Steinberg, Martin

PMID: 15543018

Ding C, Chiu RW, Lau TK, Leung TN, Chan LC, Chan AY, Charoenkwan P, Ng IS, Law HY, Ma ES, Xu X, Wanapirak C, Sanguansermsri T, Liao C, Ai MA, Chui DH, Cantor CR, Lo YM. MS analysis of single-nucleotide differences in circulating nucleic acids: Application to noninvasive prenatal diagnosis. Proc Natl Acad Sci U S A. 2004 Jul 20; 101(29):10762-7.View Related Profiles.

Chui, David
Xu, Xinjie

PMID: 15247415; PMCID: PMC490008

Wang W, Ma ES, Chan AY, Prior J, Erber WN, Chan LC, Chui DH, Chong SS. Single-tube multiplex-PCR screen for anti-3.7 and anti-4.2 alpha-globin gene triplications. Clin Chem. 2003 Oct; 49(10):1679-82. PMID: 14500599

Lafferty JD, Waye JS, Chui DH, Crawford L, Raby A, Richardson H. Good practice guidelines for laboratory investigation of hemoglobinopathies. Lab Hematol. 2003; 9(4):237-45. PMID: 14649467

Chiu RW, Lau TK, Leung TN, Chow KC, Chui DH, Lo YM. Prenatal exclusion of beta thalassaemia major by examination of maternal plasma. Lancet. 2002 Sep 28; 360(9338):998-1000. PMID: 12383672

Chui DH, Fucharoen S, Chan V. Hemoglobin H disease: not necessarily a benign disorder. Blood. 2003 Feb 1; 101(3):791-800. PMID: 12393486

Hardison RC, Chui DH, Giardine B, Riemer C, Patrinos GP, Anagnou N, Miller W, Wajcman H. HbVar: A relational database of human hemoglobin variants and thalassemia mutations at the globin gene server. Hum Mutat. 2002 Mar; 19(3):225-33. PMID: 11857738

Lorey F, Charoenkwan P, Witkowska HE, Lafferty J, Patterson M, Eng B, Waye JS, Finklestein JZ, Chui DH. Hb H hydrops foetalis syndrome: a case report and review of literature. Br J Haematol. 2001 Oct; 115(1):72-8. PMID: 11722414

Waye JS, Eng B, Patterson M, Walker L, Carcao MD, Olivieri NF, Chui DH. Hemoglobin H (Hb H) disease in Canada: molecular diagnosis and review of 116 cases. Am J Hematol. 2001 Sep; 68(1):11-5. PMID: 11559931

Su YY, Gordon CT, Ye TZ, Perkins AC, Chui DH. Human ERMAP: an erythroid adhesion/receptor transmembrane protein. Blood Cells Mol Dis. 2001 Sep-Oct; 27(5):938-49. PMID: 11783959

Lau ET, Kwok YK, Chui DH, Wong HS, Luo HY, Tang MH. Embryonic and fetal globins are expressed in adult erythroid progenitor cells and in erythroid cell cultures. Prenat Diagn. 2001 Jul; 21(7):529-39. PMID: 11494285

Chan LC, Ma SK, Chan AY, Ha SY, Waye JS, Lau YL, Chui DH. Should we screen for globin gene mutations in blood samples with mean corpuscular volume (MCV) greater than 80 fL in areas with a high prevalence of thalassaemia? J Clin Pathol. 2001 Apr; 54(4):317-20. PMID: 11304851; PMCID: PMC1731396

Horsley SW, Daniels RJ, Anguita E, Raynham HA, Peden JF, Villegas A, Vickers MA, Green S, Waye JS, Chui DH, Ayyub H, MacCarthy AB, Buckle VJ, Gibbons RJ, Kearney L, Higgs DR. Monosomy for the most telomeric, gene-rich region of the short arm of human chromosome 16 causes minimal phenotypic effects. Eur J Hum Genet. 2001 Mar; 9(3):217-25. PMID: 11313762

Chui DH, Dover GJ. Sickle cell disease: no longer a single gene disorder. Curr Opin Pediatr. 2001 Feb; 13(1):22-7. PMID: 11176239

Lorey F, Cunningham G, Vichinsky EP, Lubin BH, Witkowska HE, Matsunaga A, Azimi M, Sherwin J, Eastman J, Farina F, Waye JS, Chui DH. Universal newborn screening for Hb H disease in California. Genet Test. 2001; 5(2):93-100. PMID: 11551109

Lafferty JD, Crowther MA, Waye JS, Chui DH. A reliable screening test to identify adult carriers of the (--SEA) alpha zero-thalassemia deletion. Detection of embryonic zeta-globin chains by enzyme-linked immunosorbent assay. Am J Clin Pathol. 2000 Dec; 114(6):927-31. PMID: 11338482

Krishnamurti L, Chui DH, Dallaire M, LeRoy B, Waye JS, Perentesis JP. Coinheritance of alpha-thalassemia-1 and hemoglobin E/beta zero-thalassemia: practical implications for neonatal screening and genetic counseling. J Pediatr. 1998 May; 132(5):863-5. PMID: 9602201

Chui DH, Hardison R, Riemer C, Miller W, Carver MF, Molchanova TP, Efremov GD, Huisman TH. An electronic database of human hemoglobin variants on the World Wide Web. Blood. 1998 Apr 15; 91(8):2643-4. PMID: 9531571

Chui DH, Waye JS. Hydrops fetalis caused by alpha-thalassemia: an emerging health care problem. Blood. 1998 Apr 01; 91(7):2213-22. PMID: 9516118

Tang W, Lai YH, Han XD, Wong PM, Peters LL, Chui DH. Murine Hn1 on chromosome 11 is expressed in hemopoietic and brain tissues. Mamm Genome. 1997 Sep; 8(9):695-6. PMID: 9271675

Lau YL, Chan LC, Chan YY, Ha SY, Yeung CY, Waye JS, Chui DH. Prevalence and genotypes of alpha- and beta-thalassemia carriers in Hong Kong -- implications for population screening. N Engl J Med. 1997 May 01; 336(18):1298-301. PMID: 9113933; DOI: 10.1056/NEJM199705013361805;

Luo HY, Deisseroth AB, Chui DH. Human embryonic zeta-globin gene expression in mouse-human hybrid erythroid cell lines. Blood. 1995 Aug 01; 86(3):1212-7. PMID: 7620174

Chui DH, Tang W, Orkin SH. cDNA cloning of murine Nrf 2 gene, coding for a p45 NF-E2 related transcription factor. Biochem Biophys Res Commun. 1995 Apr 06; 209(1):40-6. PMID: 7726861

Tang W, Luo HY, Eng B, Waye JS, Chui DH. Immunocytological test to detect adult carriers of (--SEA/) deletional alpha-thalassaemia. Lancet. 1993 Nov 06; 342(8880):1145-7. PMID: 7901477

Waye JS, Eng B, Cai SP, Patterson M, Smith J, Tang W, Chui DH. Carrier detection and prenatal diagnosis of hemoglobinopathies in Ontario. Clin Invest Med. 1993 Oct; 16(5):358-71. PMID: 8261689

Tang W, Cai SP, Eng B, Poon MC, Waye JS, Illum N, Chui DH. Expression of embryonic zeta-globin and epsilon-globin chains in a 10-year-old girl with congenital anemia. Blood. 1993 Mar 15; 81(6):1636-40. PMID: 7680924

Tang W, Luo HY, Albitar M, Patterson M, Eng B, Waye JS, Liebhaber SA, Higgs DR, Chui DH. Human embryonic zeta-globin chain expression in deletional alpha-thalassemias. Blood. 1992 Jul 15; 80(2):517-22. PMID: 1627804

Waye JS, Eng B, Chui DH. Identification of an extensive zeta-alpha globin gene deletion in a Chinese individual. Br J Haematol. 1992 Mar; 80(3):378-80. PMID: 1581218

Chui DH, Patterson M, Dowling CE, Kazazian HH, Kendall AG. Hemoglobin Bart's disease in an Italian boy. Interaction between alpha-thalassemia and hereditary persistence of fetal hemoglobin. N Engl J Med. 1990 Jul 19; 323(3):179-82. PMID: 1694572; DOI: 10.1056/NEJM199007193230307;

Toles JF, Chui DH, Belbeck LW, Starr E, Barker JE. Hemopoietic stem cells in murine embryonic yolk sac and peripheral blood. Proc Natl Acad Sci U S A. 1989 Oct; 86(19):7456-9. PMID: 2571992; PMCID: PMC298083

Chui DH, Mentzer WC, Patterson M, Iarocci TA, Embury SH, Perrine SP, Mibashan RS, Higgs DR. Human embryonic zeta-globin chains in fetal and newborn blood. Blood. 1989 Sep; 74(4):1409-14.View Related Profiles.

Chui, David
Perrine-Faller, Susan

PMID: 2475189

Luo HY, Clarke BJ, Gauldie J, Patterson M, Liao SK, Chui DH. A novel monoclonal antibody based diagnostic test for alpha-thalassemia-1 carriers due to the (-SEA/) deletion. Blood. 1988 Nov; 72(5):1589-94. PMID: 3179441

Zhao JQ, Luo HY, Clarke BJ, Chui DH. An immunoassay to detect human embryonic epsilon globin chains by a murine monoclonal antibody. Blood. 1988 Apr; 71(4):883-7. PMID: 3162692

Wong PM, Chung SW, Chui DH, Eaves CJ. Properties of the earliest clonogenic hemopoietic precursors to appear in the developing murine yolk sac. Proc Natl Acad Sci U S A. 1986 Jun; 83(11):3851-4. PMID: 3012535; PMCID: PMC323622

Wong PM, Chung SW, Reicheld SM, Chui DH. Hemoglobin switching during murine embryonic development: evidence for two populations of embryonic erythropoietic progenitor cells. Blood. 1986 Mar; 67(3):716-21. PMID: 3947744

Chui DH, Wong SC, Chung SW, Patterson M, Bhargava S, Poon MC. Embryonic zeta-globin chains in adults: a marker for alpha-thalassemia-1 haplotype due to a greater than 17.5-kb deletion. N Engl J Med. 1986 Jan 09; 314(2):76-9. PMID: 3941693; DOI: 10.1056/NEJM198601093140203;

Chung SW, Wong SC, Clarke BJ, Patterson M, Walker WH, Chui DH. Human embryonic zeta-globin chains in adult patients with alpha-thalassemias. Proc Natl Acad Sci U S A. 1984 Oct; 81(19):6188-91. PMID: 6592610; PMCID: PMC391885

Chui DH, Clarke BJ. Abnormal erythroid progenitor cells in human preleukemia. Blood. 1982 Aug; 60(2):362-7. PMID: 6980031

Wong PM, Clarke BJ, Carr DH, Chui DH. Adult hemoglobins are synthesized in erythroid colonies in vitro derived from murine circulating hemopoietic progenitor cells during embryonic development. Proc Natl Acad Sci U S A. 1982 May; 79(9):2952-6. PMID: 6953440; PMCID: PMC346326

Chui DH, Wong SC, Enkin MW, Patterson M, Ives RA. Proportion of fetal hemoglobin synthesis decreases during erythroid cell maturation. Proc Natl Acad Sci U S A. 1980 May; 77(5):2757-61. PMID: 6156456; PMCID: PMC349483

Brotherton TW, Chui DH, Gauldie J, Patterson M. Hemoglobin ontogeny during normal mouse fetal development. Proc Natl Acad Sci U S A. 1979 Jun; 76(6):2853-7. PMID: 111244; PMCID: PMC383707

Chui DH, Liao SK, Walker K. Fetal erythropoiesis in steel mutant mice. III. Defect in differentiation from BFU-E to CFU-E during early development. Blood. 1978 Mar; 51(3):539-47. PMID: 623914

Chui DH, Sweeney GD, Patterson M, Russell ES. Hemoglobin synthesis in siderocytes of flexed-tailed mutant (f/f) fetal mice. Blood. 1977 Jul; 50(1):165-77. PMID: 559515

Chui DH, Russell ES. Fetal erythropoiesis in steel mutant mice. I. A morphological study of erythroid cell development in fetal liver. Dev Biol. 1974 Oct; 40(2):256-69. PMID: 4430409

Chui DH, Djaldetti M, Marks PA, Rifkind RA. Erythropoietin effects on fetal mouse erythroid cells. I. Cell population and hemoglobin synthesis. J Cell Biol. 1971 Dec; 51(3):585-95. PMID: 5128349; PMCID: PMC2108037

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 131 publications over 35 distinct years, with a maximum of 11 publications in 2013

Bar chart showing 131 publications over 35 distinct years, with a maximum of 11 publications in 2013

Year	Publications
1980	1
1982	2
1984	1
1986	3
1988	2
1989	2
1990	1
1992	2
1993	3
1995	2
1997	2
1998	3
2000	1
2001	8
2002	3
2003	2
2004	2
2005	6
2006	4
2007	4
2008	6
2009	5
2010	3
2011	10
2012	5
2013	11
2014	3
2015	6
2016	6
2017	6
2018	6
2019	4
2020	1
2021	3
2022	2