Martin Steinberg | Profiles RNS

Martin H. Steinberg, MD

Professor

Boston University Chobanian & Avedisian School of Medicine

Medicine

Hematology & Medical Oncology

MD, Tufts University School of Medicine
AB, Cornell University

Websites

	Center of Excellence in Sickle Cell Disease
	Hematology & Medical Oncology Faculty
	Boston Medical Center Provider Profile
	Google Scholar

ORCID : 0000-0001-8800-8020

Martin H Steinberg, MD, is a hematologist/internist whose clinical and research focus has been on disorders of the red blood cell with special emphasis on sickle cell disease. He has published 450 articles and 3 textbooks on the science and clinical features of sickle cell disease and related disorders. A graduate of Cornell University and Tufts University School of Medicine he completed post-graduate training in New York and Boston. He conducts basic, translational and clinical studies devoted to understanding the pathophysiology and genetic basis of sickle cell phenotypic heterogeneity. He modeled the HbF concentration among red blood cells showing that only patients with very high HbF levels were likely to have major benefit, therefor setting a standard for HbF induction therapies. He identified cis- and trans-acting elements that help explain the high HbF levels of Saudi patients from the Eastern Province whose sickle hemoglobin gene is associated with the Arab-Indian haplotype. Using candidate gene, genome-wide association studies and next-generation sequencing to understand the genetic determinants of sickle cell disease heterogeneity, Dr. Steinberg and his coworkers modeled disease severity and selected subphenotypes of disease to discover hitherto unsuspected genetic associations. He has also reimagined the pathophysiologic features of sickle cell anemia, establishing with his collaborators a new widely accepted paradigm that the pathophysiology of sickle cell disease is a combination of both sickle vasoocclusion and intravascular hemolysis that has important prognostic and therapeutic implications. He also reported the first of a new class of hemoglobin disorders, the thalassemic hemoglobinopathies, wherein a single exonic mutation causes both a variant hemoglobin but also phenotype of thalassemia because of hemoglobin hyper-instability and catabolism.

Diversity, Equity, Inclusion and Accessibility

Dr. Steinberg champions equal opportunity and treatment for everybody.

Professor
Boston University Chobanian & Avedisian School of Medicine
Pathology & Laboratory Medicine

Professor
Boston University Chobanian & Avedisian School of Medicine
Pediatrics

Member
Boston University
Center for Regenerative Medicine

Member
Boston University
Center for Excellence in Sickle Cell Disease

Member
Boston University
Evans Center for Interdisciplinary Biomedical Research

Member
Boston University
Genome Science Institute

Graduate Faculty (Primary Mentor of Grad Students)
Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences

Research Training in Blood Diseases and Resources
06/01/2014 - 05/31/2021 (Multi-PI)
PI: Martin H. Steinberg, MD
NIH/National Heart, Lung, and Blood Institute
5T32HL007501-36

Mechanisms of cis-acting HbF regulation in sickle cell anemia
04/01/2017 - 03/31/2021 (Multi-PI)
PI: Martin H. Steinberg, MD
Boston Medical Center Corporation NIH NHLBI
5R01HL133350-04

Severity Index for Sickle Cell anemia in the Eastern Province of Saudi Arabia
01/01/2013 - 12/31/2018 (PI)
King Faisal University

A prototype diagnostic for cellular fetal hemoglobin in sickle cell disease
08/01/2016 - 01/31/2018 (Multi-PI)
PI: Martin H. Steinberg, MD
MyoSyntax Corporation NIH NHLBI
1R43HL134529-01

Globin Gene Expression in Sickle Cell Genotype-Specific iPS cells
07/05/2011 - 06/30/2017 (Multi-PI)
PI: Martin H. Steinberg, MD
NIH/National Heart, Lung, and Blood Institute
5U01HL107443-05

Genetic Basis of Fetal Hemoglobin in Saudi Sickle Cell Anemia
01/02/2012 - 12/31/2016 (PI)
University of Dammam Saudi Arabia

Globin Gene Expression in Sickle Cell Genotype-Specific iPS cells
07/05/2011 - 06/30/2016 (PI)
NIH/National Heart, Lung, and Blood Institute
1U01HL107443-01

A prototype diagnostic for cellular fetal hemoglobin in sickle cell disease
08/15/2014 - 01/30/2016 (Subcontract PI)
MyoSyntax Corporation NIH NHLBI
1R43HL124679-01

Gene Polymorphism in Chronic Sickle Cell Lung Disease
01/01/2005 - 12/31/2009 (Dept Sponsor)
NIH/National Heart, Lung, and Blood Institute
5 K23 HL79003 05

Genetic Modulation of Sickle Cell Anemia
05/01/2006 - 04/30/2009 (PI)
NIH/Fogarty International Center
5 R03 TW07189 03

Showing 10 of 13 results. Show All Results

BTRP Admin Core
04/01/2008 - 03/31/2012 (PI)
NIH-NHLBI
5U54 HL070819-08

BTRP Clinical Trials
04/01/2008 - 03/31/2012 (PI)
NIH-NHLBI
5U54 HL070819-07

BTRP Research Scholar
04/01/2008 - 03/31/2012 (PI)
NIH-NHLBI
5U54 HL070819-07

BTRP Subcontracts
04/01/2008 - 03/31/2012 (PI)
NIH-NHLBI
5U54 HL070819-08

BTRP Training Supplement
04/01/2008 - 03/31/2012 (PI)
NIH-NHLBI
2U54 HL070819-06

CSSC Admin Core
04/01/2008 - 03/31/2012 (PI)
NIH-NHLBI
2U54 HL070819-06

CSSC Butyrate
04/01/2008 - 03/31/2012 (PI)
NIH-NHLBI
2U54 HL070819-06

CSSC Clinical Core
04/01/2008 - 03/31/2012 (PI)
NIH-NHLBI
2U54 HL070819-06

CSSC Geno-Pheno Core Lab
04/01/2008 - 03/31/2012 (PI)
NIH-NHLBI
2U54 HL070819-06

CSSC Patient Service Core
04/01/2008 - 03/31/2012 (PI)
NIH-NHLBI
2U54 HL070819-06

Showing 10 of 18 results. Show All Results

Title

Yr	Title	Project-Sub Proj	Pubs
2020	Mechanisms of cis-acting HbF regulation in sickle cell anemia	5R01HL133350-04	11
2019	Mechanisms of cis-acting HbF regulation in sickle cell anemia	5R01HL133350-03	11
2018	Mechanisms of cis-acting HbF regulation in sickle cell anemia	5R01HL133350-02	11
2018	Research Training in Blood Diseases and Resources	5T32HL007501-36	119
2017	Mechanisms of cis-acting HbF regulation in sickle cell anemia	1R01HL133350-01A1	11
2017	Research Training in Blood Diseases and Resources	5T32HL007501-35	119
2016	A prototype diagnostic for cellular fetal hemoglobin in sickle cell disease	1R43HL134529-01
2016	Research Training in Blood Diseases and Resources	5T32HL007501-34	119
2015	Globin Gene Expression in Sickle Cell Genotype-Specific iPS cells	5U01HL107443-05	16
2015	Research Training in Blood Diseases and Resources	5T32HL007501-33	119

Showing 10 of 73 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

McManus M, Frangoul H, Steinberg MH. Crispr-based gene therapy for the induction of fetal hemoglobin in sickle cell disease. Expert Rev Hematol. 2024 Nov 13. PMID: 39535263

Sun Y, Benmhammed H, Al Abdullatif S, Habara A, Fu E, Brady J, Williams C, Ilinski A, Sharma A, Mahdaviani K, Alekseyev YO, Campbell JD, Steinberg MH, Cui S. PGC-1a agonism induces fetal hemoglobin and exerts antisickling effects in sickle cell disease. Sci Adv. 2024 Aug 02; 10(31):eadn8750.View Related Profiles.

Benmhammed, Hajar
Campbell, Joshua
Mahdaviani, Kiana
Steinberg, Martin
Cui, Shuaiying
Alekseyev, Yuriy

PMID: 39083598; PMCID: PMC11290485; DOI: 10.1126/sciadv.adn8750;

Frangoul H, Locatelli F, Sharma A, Bhatia M, Mapara M, Molinari L, Wall D, Liem RI, Telfer P, Shah AJ, Cavazzana M, Corbacioglu S, Rondelli D, Meisel R, Dedeken L, Lobitz S, de Montalembert M, Steinberg MH, Walters MC, Eckrich MJ, Imren S, Bower L, Simard C, Zhou W, Xuan F, Morrow PK, Hobbs WE, Grupp SA. Exagamglogene Autotemcel for Severe Sickle Cell Disease. N Engl J Med. 2024 May 09; 390(18):1649-1662.View Related Profiles.

Sharma, Akshay
Steinberg, Martin

PMID: 38661449

Heitzer AM, Rashkin SR, Trpchevska A, Longoria JN, Rampersaud E, Olufadi Y, Wang WC, Raches D, Potter B, Steinberg MH, King AA, Kang G, Takemoto CM, Hankins JS. Catechol-O-methyltransferase gene (COMT) is associated with neurocognitive functioning in patients with sickle cell disease. Curr Res Transl Med. 2024 Jun; 72(2):103433. PMID: 38244277; PMCID: PMC11106217; DOI: 10.1016/j.retram.2023.103433;

Steinberg MH, Gladwin MT. "Severity" in adult sickle cell disease. Am J Hematol. 2023 Oct; 98(10):1508-1511. PMID: 37449407

Ribeil JA, Pollock G, Frangoul H, Steinberg MH. An integrated therapeutic approach to sickle cell disease management beyond infancy. Am J Hematol. 2023 Jul; 98(7):1087-1096.View Related Profiles.

Pollock, Galia
Steinberg, Martin

PMID: 37170801

Sebastiani P, Steinberg MH. Fetal hemoglobin per erythrocyte (HbF/F-cell) after gene therapy for sickle cell anemia. Am J Hematol. 2023 Feb; 98(2):E32-E34.View Related Profiles.

Steinberg, Martin
Sebastiani, Paola

PMID: 36420999

Cyrus C, Vatte C, Al-Nafie A, Chathoth S, Akhtar MS, Darwish M, Almohazey D, AlDubayan SH, Steinberg MH, Al-Ali A. miRNA Expression Associated with HbF in Saudi Sickle Cell Anemia. Medicina (Kaunas). 2022 Oct 17; 58(10). PMID: 36295630; PMCID: PMC9611475; DOI: 10.3390/medicina58101470;

Minniti C, Brugnara C, Steinberg MH. HbSC disease: A time for progress. Am J Hematol. 2022 Nov; 97(11):1390-1393. PMID: 36073655

Steinberg MH. World Sickle Cell Day 2022: Progress & prospects. Indian J Med Res. 2022 Jul; 156(1):10-13. PMID: 35946231; PMCID: PMC9903380; DOI: 10.4103/ijmr.ijmr_1049_22;

Showing 10 of 365 results. Show More

Steinberg MH. Targeting fetal hemoglobin expression to treat ß hemoglobinopathies. Expert Opin Ther Targets. 2022 Apr; 26(4):347-359. PMID: 35418266

Steinberg MH. Fetal hemoglobin in ß hemoglobinopathies: Is enough too much? Am J Hematol. 2022 Jun 01; 97(6):676-678. PMID: 35253929

Heitzer AM, Longoria J, Rampersaud E, Rashkin SR, Estepp JH, Okhomina VI, Wang WC, Raches D, Potter B, Steinberg MH, King AA, Kang G, Hankins JS. Fetal hemoglobin modulates neurocognitive performance in sickle cell anemia?,??. Curr Res Transl Med. 2022 Jul; 70(3):103335. PMID: 35303690; PMCID: PMC9086114; DOI: 10.1016/j.retram.2022.103335;

Steinberg MH. Fetal-like Hemoglobin in Sickle Cell Anemia. N Engl J Med. 2022 02 17; 386(7):689-691. PMID: 35172060

Klings ES, Steinberg MH. Acute chest syndrome of sickle cell disease: genetics, risk factors, prognosis, and management. Expert Rev Hematol. 2022 Feb; 15(2):117-125.View Related Profiles.

Klings, Elizabeth
Steinberg, Martin

PMID: 35143368

Sun Y, Habara A, Le CQ, Nguyen N, Chen R, Murphy GJ, Chui DHK, Steinberg MH, Cui S. Pharmacologic induction of PGC-1a stimulates fetal haemoglobin gene expression. Br J Haematol. 2022 Apr; 197(1):97-109.View Related Profiles.

Le, Cuong
Chui, David
Murphy, George
Steinberg, Martin
Cui, Shuaiying

PMID: 35118652

Patrinos GP, Chui DHK, Hardison RC, Steinberg MH. Strategies to improve pharmacogenomic-guided treatment options for patients with ß-hemoglobinopathies. Expert Rev Hematol. 2021 10; 14(10):883-885.View Related Profiles.

Chui, David
Steinberg, Martin

PMID: 34490838; PMCID: PMC9306350; DOI: 10.1080/17474086.2021.1977117;

Steinberg MH. HbA2 induction: the merit of pancellularity in sickle cell disease. Br J Haematol. 2021 06; 193(6):1032-1033. PMID: 34060070

Alnafie AN, Alateeq SA, Al-Muhanna FA, Alsulaiman AM, Alfarhan M, Buali W, Vatte CB, Cyrus C, Keating B, Al-Ali AK, Steinberg MH. Exome sequencing in high and low fetal haemoglobin Arab-Indian haplotype sickle cell disease. Br J Haematol. 2021 07; 194(2):e61-e64. PMID: 34041755

Al-Ali AK, Alsulaiman A, Alfarhan M, Safaya S, Vatte CB, Albuali WM, Qutub HO, Alzahrani AJ, Milton JN, Steinberg MH. Sickle cell disease in the Eastern Province of Saudi Arabia: Clinical and laboratory features. Am J Hematol. 2021 04 01; 96(4):E117-E121.View Related Profiles.

Alsulaiman, Ahmed
Steinberg, Martin

PMID: 33460474

Frangoul H, Altshuler D, Cappellini MD, Chen YS, Domm J, Eustace BK, Foell J, de la Fuente J, Grupp S, Handgretinger R, Ho TW, Kattamis A, Kernytsky A, Lekstrom-Himes J, Li AM, Locatelli F, Mapara MY, de Montalembert M, Rondelli D, Sharma A, Sheth S, Soni S, Steinberg MH, Wall D, Yen A, Corbacioglu S. CRISPR-Cas9 Gene Editing for Sickle Cell Disease and ß-Thalassemia. N Engl J Med. 2021 01 21; 384(3):252-260.View Related Profiles.

Sharma, Akshay
Steinberg, Martin

PMID: 33283989

Steinberg MH. Fetal Hemoglobin in Sickle Hemoglobinopathies: High HbF Genotypes and Phenotypes. J Clin Med. 2020 Nov 23; 9(11). PMID: 33238542; PMCID: PMC7700170; DOI: 10.3390/jcm9113782;

Steinberg MH. Fetal hemoglobin in sickle cell anemia. Blood. 2020 11 19; 136(21):2392-2400. PMID: 32808012; PMCID: PMC7685210; DOI: 10.1182/blood.2020007645;

Al-Ali AK, Alsulaiman A, Alzahrani AJ, Obeid OT, Vatte CB, Cyrus C, Alnafie AN, Alali RA, Alfarhan M, Mozeleski B, Steinberg MH. Prevalence and Diversity of Haplotypes of Sickle Cell Disease in the Eastern Province of Saudi Arabia. Hemoglobin. 2020 Mar; 44(2):78-81.View Related Profiles.

Alsulaiman, Ahmed
Steinberg, Martin

PMID: 32448003

Kanchan K, Iyer K, Yanek LR, Carcamo-Orive I, Taub MA, Malley C, Baldwin K, Becker LC, Broeckel U, Cheng L, Cowan C, D'Antonio M, Frazer KA, Quertermous T, Mostoslavsky G, Murphy G, Rabinovitch M, Rader DJ, Steinberg MH, Topol E, Yang W, Knowles JW, Jaquish CE, Ruczinski I, Mathias RA. Genomic integrity of human induced pluripotent stem cells across nine studies in the NHLBI NextGen program. Stem Cell Res. 2020 07; 46:101803.View Related Profiles.

Murphy, George
Mostoslavsky, Gustavo
Steinberg, Martin

PMID: 32442913; PMCID: PMC7575060; DOI: 10.1016/j.scr.2020.101803;

Willen SM, McNeil JB, Rodeghier M, Kerchberger VE, Shaver CM, Bastarache JA, Steinberg MH, DeBaun MR, Ware LB. Haptoglobin genotype predicts severe acute vaso-occlusive pain episodes in children with sickle cell anemia. Am J Hematol. 2020 04; 95(4):E92-E95. PMID: 31919880; PMCID: PMC7343605; DOI: 10.1002/ajh.25728;

Steinberg MH. Treating sickle cell anemia: A new era dawns. Am J Hematol. 2020 04; 95(4):338-342. PMID: 31925819

Steinberg MH, Kumar S, Murphy GJ, Vanuytsel K. Sickle cell disease in the era of precision medicine: looking to the future. Expert Rev Precis Med Drug Dev. 2019; 4(6):357-367.View Related Profiles.

Murphy, George
Vanuytsel, Kim
Steinberg, Martin

PMID: 33015364; PMCID: PMC7531762; DOI: 10.1080/23808993.2019.1688658;

Dai Y, Shaikho EM, Perez J, Wilson CA, Liu LY, White MR, Farrell JJ, Chui DHK, Sebastiani P, Steinberg MH. BCL2L1 is associated with ?-globin gene expression. Blood Adv. 2019 10 22; 3(20):2995-3001.View Related Profiles.

Chui, David
Steinberg, Martin
Sebastiani, Paola
Dai, Yan

PMID: 31648320; PMCID: PMC6849934; DOI: 10.1182/bloodadvances.2019032243;

Steinberg MH. "Sickling" in vertebrates: Animal studies vs. sickle cell disease. Blood Rev. 2019 07; 36:88-94. PMID: 31084943

Steinberg MH. Primary polymerization prevention. Blood. 2019 04 25; 133(17):1797-1798. PMID: 31023742

Le CQ, Myers G, Habara A, Jearawiriyapaisarn N, Murphy GJ, Chui DHK, Steinberg MH, Engel JD, Cui S. Inhibition of LSD1 by small molecule inhibitors stimulates fetal hemoglobin synthesis. Blood. 2019 05 30; 133(22):2455-2459.View Related Profiles.

Le, Cuong
Chui, David
Murphy, George
Steinberg, Martin
Cui, Shuaiying

PMID: 30992270; PMCID: PMC6543516; DOI: 10.1182/blood.2018892737;

Milton JN, Shaikho EM, Steinberg MH. Haemolysis in sickle cell anaemia: effects of polymorphisms in a-globin gene regulatory elements. Br J Haematol. 2019 07; 186(2):363-364.View Related Profiles.

Hicks, Jacqueline
Steinberg, Martin

PMID: 30854637; PMCID: PMC6606385; DOI: 10.1111/bjh.15852;

Steinberg MH, Schechter AN. Airlie House legend. Am J Hematol. 2018 12; 93(12):1566-1567. PMID: 30242871

Steinberg MH. A New Trans-Acting Modulator of Fetal Hemoglobin? Acta Haematol. 2018; 140(2):112-113. PMID: 30227393

Vanuytsel K, Matte T, Leung A, Naing ZH, Morrison T, Chui DHK, Steinberg MH, Murphy GJ. Induced pluripotent stem cell-based mapping of ß-globin expression throughout human erythropoietic development. Blood Adv. 2018 08 14; 2(15):1998-2011.View Related Profiles.

Chui, David
Murphy, George
Vanuytsel, Kim
Steinberg, Martin
Matte, Taylor

PMID: 30108108; PMCID: PMC6093724; DOI: 10.1182/bloodadvances.2018020560;

Du M, Van Ness S, Gordeuk V, Nouraie SM, Nekhai S, Gladwin M, Steinberg MH, Sebastiani P. Biomarker signatures of sickle cell disease severity. Blood Cells Mol Dis. 2018 09; 72:1-9.View Related Profiles.

Steinberg, Martin
Sebastiani, Paola

PMID: 29778312; PMCID: PMC6087499; DOI: 10.1016/j.bcmd.2018.05.001;

Leung A, Zulick E, Skvir N, Vanuytsel K, Morrison TA, Naing ZH, Wang Z, Dai Y, Chui DHK, Steinberg MH, Sherr DH, Murphy GJ. Notch and Aryl Hydrocarbon Receptor Signaling Impact Definitive Hematopoiesis from Human Pluripotent Stem Cells. Stem Cells. 2018 07; 36(7):1004-1019.View Related Profiles.

Sherr, David
Chui, David
Murphy, George
Vanuytsel, Kim
Steinberg, Martin
Morrison, Tasha
Dai, Yan
Wang, Zhongyan

PMID: 29569827; PMCID: PMC6099224; DOI: 10.1002/stem.2822;

Akinbami AO, Sobota AE, Luo HY, Chui DHK, Steinberg MH. A Mild Phenotype of Severe ß+ Thalassemia in a 16-Month-Old Boy. J Pediatr Hematol Oncol. 2018 04; 40(3):e145-e147.View Related Profiles.

Sobota, Amy
Chui, David
Steinberg, Martin

PMID: 29309373

Morrison TA, Wilcox I, Luo HY, Farrell JJ, Kurita R, Nakamura Y, Murphy GJ, Cui S, Steinberg MH, Chui DHK. A long noncoding RNA from the HBS1L-MYB intergenic region on chr6q23 regulates human fetal hemoglobin expression. Blood Cells Mol Dis. 2018 03; 69:1-9.View Related Profiles.

Chui, David
Murphy, George
Luo, Hong
Steinberg, Martin
Cui, Shuaiying
Morrison, Tasha

PMID: 29227829; PMCID: PMC5783741; DOI: 10.1016/j.bcmd.2017.11.003;

Dai Y, Chen T, Ijaz H, Cho EH, Steinberg MH. SIRT1 activates the expression of fetal hemoglobin genes. Am J Hematol. 2017 Nov; 92(11):1177-1186.View Related Profiles.

Steinberg, Martin
Dai, Yan

PMID: 28776729; PMCID: PMC5648331; DOI: 10.1002/ajh.24879;

Habara AH, Shaikho EM, Steinberg MH. Fetal hemoglobin in sickle cell anemia: The Arab-Indian haplotype and new therapeutic agents. Am J Hematol. 2017 Nov; 92(11):1233-1242. PMID: 28736939; PMCID: PMC5647233; DOI: 10.1002/ajh.24872;

Shaikho EM, Farrell JJ, Alsultan A, Qutub H, Al-Ali AK, Figueiredo MS, Chui DHK, Farrer LA, Murphy GJ, Mostoslavsky G, Sebastiani P, Steinberg MH. A phased SNP-based classification of sickle cell anemia HBB haplotypes. BMC Genomics. 2017 Aug 11; 18(1):608.View Related Profiles.

Chui, David
Murphy, George
Mostoslavsky, Gustavo
Farrer, Lindsay
Steinberg, Martin
Sebastiani, Paola

PMID: 28800727; PMCID: PMC5553663; DOI: 10.1186/s12864-017-4013-y;

Piel FB, Steinberg MH, Rees DC. Sickle Cell Disease. N Engl J Med. 2017 07 20; 377(3):305. PMID: 28723338

Shaikho EM, Farrell JJ, Alsultan A, Sebastiani P, Steinberg MH. Genetic determinants of HbF in Saudi Arabian and African Benin haplotype sickle cell anemia. Am J Hematol. 2017 09; 92(9):E555-E557.View Related Profiles.

Steinberg, Martin
Sebastiani, Paola

PMID: 28612458; PMCID: PMC5546992; DOI: 10.1002/ajh.24822;

Chaturvedi S, Bhatnagar P, Bean CJ, Steinberg MH, Milton JN, Casella JF, Barron-Casella E, Arking DE, DeBaun MR. Genome-wide association study to identify variants associated with acute severe vaso-occlusive pain in sickle cell anemia. Blood. 2017 08 03; 130(5):686-688.View Related Profiles.

Hicks, Jacqueline
Steinberg, Martin

PMID: 28584135; PMCID: PMC5542853; DOI: 10.1182/blood-2017-02-769661;

Piel FB, Steinberg MH, Rees DC. Sickle Cell Disease. N Engl J Med. 2017 04 20; 376(16):1561-1573. PMID: 28423290; DOI: 10.1056/NEJMra1510865;

Aleluia MM, Santiago RP, da Guarda CC, Fonseca TC, Neves FI, Quinto RS, Figueiredo CV, Yahouédéhou SC, Oliveira RM, Ferreira JR, Cerqueira BA, Barbosa CG, Milton JN, Steinberg MH, de Souza Gonçalves M. Genetic modulation of fetal hemoglobin in hydroxyurea-treated sickle cell anemia. Am J Hematol. 2017 May; 92(5):E70-E72.View Related Profiles.

Hicks, Jacqueline
Steinberg, Martin

PMID: 28195442; PMCID: PMC5389903; DOI: 10.1002/ajh.24680;

Kato GJ, Steinberg MH, Gladwin MT. Intravascular hemolysis and the pathophysiology of sickle cell disease. J Clin Invest. 2017 Mar 01; 127(3):750-760. PMID: 28248201; PMCID: PMC5330745; DOI: 10.1172/JCI89741;

Jiang Z, Luo HY, Farrell JJ, Zhang Z, Schulz VP, Albarawi D, Steinberg MH, Al-Allawi NAS, Gallagher PG, Forget BG, Chui DHK. A variant Sp1 (R218Q) transcription factor might enhance HbF expression in ß0 -thalassaemia homozygotes. Br J Haematol. 2018 03; 180(5):755-757.View Related Profiles.

Chui, David
Luo, Hong
Steinberg, Martin
Jiang, Zhihua

PMID: 28240767; DOI: 10.1111/bjh.14445;

Cyrus C, Vatte C, Borgio JF, Al-Rubaish A, Chathoth S, Nasserullah ZA, Jarrash SA, Sulaiman A, Qutub H, Alsaleem H, Alzahrani AJ, Steinberg MH, Ali AK. Existence of HbF Enhancer Haplotypes at HBS1L-MYB Intergenic Region in Transfusion-Dependent Saudi ß-Thalassemia Patients. Biomed Res Int. 2017; 2017:1972429. PMID: 28280727; PMCID: PMC5322420; DOI: 10.1155/2017/1972429;

Steinberg MH. Go with the Flow. N Engl J Med. 2017 02 02; 376(5):485-487. PMID: 28146663; DOI: 10.1056/NEJMe1615651;

Park S, Gianotti-Sommer A, Molina-Estevez FJ, Vanuytsel K, Skvir N, Leung A, Rozelle SS, Shaikho EM, Weir I, Jiang Z, Luo HY, Chui DHK, Figueiredo MS, Alsultan A, Al-Ali A, Sebastiani P, Steinberg MH, Mostoslavsky G, Murphy GJ. A Comprehensive, Ethnically Diverse Library of Sickle Cell Disease-Specific Induced Pluripotent Stem Cells. Stem Cell Reports. 2017 Apr 11; 8(4):1076-1085.View Related Profiles.

Chui, David
Murphy, George
Mostoslavsky, Gustavo
Luo, Hong
Vanuytsel, Kim
Steinberg, Martin
Sebastiani, Paola
Jiang, Zhihua

PMID: 28111279; PMCID: PMC5390092; DOI: 10.1016/j.stemcr.2016.12.017;

Dai Y, Sangerman J, Nouraie M, Faller AD, Oneal P, Rock A, Owoyemi O, Niu X, Nekhai S, Maharaj D, Cui S, Taylor R, Steinberg M, Perrine S. Effects of hydroxyurea on F-cells in sickle cell disease and potential impact of a second fetal globin inducer. Am J Hematol. 2017 Jan; 92(1):E10-E11.View Related Profiles.

Sangerman, Jose
Steinberg, Martin
Cui, Shuaiying
Dai, Yan

PMID: 27766663; PMCID: PMC5167623; DOI: 10.1002/ajh.24590;

Vathipadiekal V, Farrell JJ, Wang S, Edward HL, Shappell H, Al-Rubaish AM, Al-Muhanna F, Naserullah Z, Alsuliman A, Qutub HO, Simkin I, Farrer LA, Jiang Z, Luo HY, Huang S, Mostoslavsky G, Murphy GJ, Patra PK, Chui DH, Alsultan A, Al-Ali AK, Sebastiani P, Steinberg MH. A candidate transacting modulator of fetal hemoglobin gene expression in the Arab-Indian haplotype of sickle cell anemia. Am J Hematol. 2016 Nov; 91(11):1118-1122.View Related Profiles.

Chui, David
Murphy, George
Mostoslavsky, Gustavo
Luo, Hong
Farrer, Lindsay
Steinberg, Martin
Sebastiani, Paola
Vathipadiekal, Vinod
Jiang, Zhihua

PMID: 27501013; PMCID: PMC5072989; DOI: 10.1002/ajh.24527;

Bae H, Monti S, Montano M, Steinberg MH, Perls TT, Sebastiani P. Learning Bayesian Networks from Correlated Data. Sci Rep. 2016 05 05; 6:25156.View Related Profiles.

Steinberg, Martin
Sebastiani, Paola
Monti, Stefano
Perls, Thomas

PMID: 27146517; PMCID: PMC4857179; DOI: 10.1038/srep25156;

Vathipadiekal V, Alsultan A, Baltrusaitis K, Farrell JJ, Al-Rubaish AM, Al-Muhanna F, Naserullah Z, Suliman A, Patra PK, Milton JN, Farrer LA, Chui DH, Al-Ali AK, Sebastiani P, Steinberg MH. Homozygosity for a haplotype in the HBG2-OR51B4 region is exclusive to Arab-Indian haplotype sickle cell anemia. Am J Hematol. 2016 06; 91(6):E308-11.View Related Profiles.

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PMID: 27185208; PMCID: PMC4874527; DOI: 10.1002/ajh.24368;

Shaikho EM, Habara AH, Alsultan A, Al-Rubaish AM, Al-Muhanna F, Naserullah Z, Alsuliman A, Qutub HO, Patra PK, Sebastiani P, Baltrusaitis K, Farrell JJ, Jiang Z, Luo HY, Chui DH, Al-Ali AK, Steinberg MH. Variants of ZBTB7A (LRF) and its ß-globin gene cluster binding motifs in sickle cell anemia. Blood Cells Mol Dis. 2016 07; 59:49-51.View Related Profiles.

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Liu L, Pertsemlidis A, Ding LH, Story MD, Steinberg MH, Sebastiani P, Hoppe C, Ballas SK, Pace BS. Original Research: A case-control genome-wide association study identifies genetic modifiers of fetal hemoglobin in sickle cell disease. Exp Biol Med (Maywood). 2016 Apr; 241(7):706-18.View Related Profiles.

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Habara A, Steinberg MH. Minireview: Genetic basis of heterogeneity and severity in sickle cell disease. Exp Biol Med (Maywood). 2016 Apr; 241(7):689-96. PMID: 26936084; PMCID: PMC4950383; DOI: 10.1177/1535370216636726;

Borgio JF, AbdulAzeez S, Naserullah ZA, Al-Jarrash S, Al-Ali RA, Al-Madan MS, Al-Muhanna F, Al-Suliman AM, Al-Nafie A, Steinberg MH, Al-Ali AK. Mutations in the ß-globin gene from a Saudi population: an update. Int J Lab Hematol. 2016 Apr; 38(2):e38-40. PMID: 26822801; DOI: 10.1111/ijlh.12463;

Jiang Z, Luo HY, Huang S, Farrell JJ, Davis L, Théberge R, Benson KA, Riolueang S, Viprakasit V, Al-Allawi NA, Ünal S, Gümrük F, Akar N, Basak AN, Osorio L, Badens C, Pissard S, Joly P, Campbell AD, Gallagher PG, Steinberg MH, Forget BG, Chui DH. The genetic basis of asymptomatic codon 8 frame-shift (HBB:c25_26delAA) ß(0) -thalassaemia homozygotes. Br J Haematol. 2016 Mar; 172(6):958-65.View Related Profiles.

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PMID: 26771086; DOI: 10.1111/bjh.13909;

Maron BJ, Harris KM, Thompson PD, Eichner ER, Steinberg MH. Eligibility and Disqualification Recommendations for Competitive Athletes With Cardiovascular Abnormalities: Task Force 14: Sickle Cell Trait: A Scientific Statement From the American Heart Association and American College of Cardiology. J Am Coll Cardiol. 2015 Dec 1; 66(21):2444-6. PMID: 26542668; DOI: 10.1016/j.jacc.2015.09.046;

Maron BJ, Harris KM, Thompson PD, Eichner ER, Steinberg MH. Eligibility and Disqualification Recommendations for Competitive Athletes With Cardiovascular Abnormalities: Task Force 14: Sickle Cell Trait: A Scientific Statement From the American Heart Association and American College of Cardiology. Circulation. 2015 Dec 1; 132(22):e343-5. PMID: 26527715; DOI: 10.1161/CIR.0000000000000250;

Akinbami AO, Campbell AD, Han ZJ, Luo HY, Chui DH, Steinberg MH. Hereditary Persistence of Fetal Hemoglobin Caused by Single Nucleotide Promoter Mutations in Sickle Cell Trait and Hb SC Disease. Hemoglobin. 2016; 40(1):64-5.View Related Profiles.

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Ngo DA, Steinberg MH. Genomic approaches to identifying targets for treating ß hemoglobinopathies. BMC Med Genomics. 2015; 8:44.View Related Profiles.

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Steinberg MH, Rodgers GP. HbA2 : biology, clinical relevance and a possible target for ameliorating sickle cell disease. Br J Haematol. 2015 Sep; 170(6):781-7. PMID: 26104837; DOI: 10.1111/bjh.13570;

Zhang X, Zhang W, Saraf SL, Nouraie M, Han J, Gowhari M, Hassan J, Miasnikova G, Sergueeva A, Nekhai S, Kittles R, Machado RF, Garcia JG, Gladwin MT, Steinberg MH, Sebastiani P, McClain DA, Gordeuk VR. Genetic polymorphism of APOB is associated with diabetes mellitus in sickle cell disease. Hum Genet. 2015 Aug; 134(8):895-904.View Related Profiles.

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Sobota A, Sabharwal V, Fonebi G, Steinberg M. How we prevent and manage infection in sickle cell disease. Br J Haematol. 2015 Sep; 170(6):757-67.View Related Profiles.

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Al-Nafie AN, Borgio JF, AbdulAzeez S, Al-Suliman AM, Qaw FS, Naserullah ZA, Al-Jarrash S, Al-Madan MS, Al-Ali RA, AlKhalifah MA, Al-Muhanna F, Steinberg MH, Al-Ali AK. Co-inheritance of novel ATRX gene mutation and globin (a & ß) gene mutations in transfusion dependent beta-thalassemia patients. Blood Cells Mol Dis. 2015 Jun; 55(1):27-9. PMID: 25976463; DOI: 10.1016/j.bcmd.2015.03.008;

Bae H, Perls T, Steinberg M, Sebastiani P. Bayesian Polynomial Regression Models to Fit Multiple Genetic Models for Quantitative Traits. Bayesian Anal. 2015 Mar; 10(1):53-74.View Related Profiles.

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Sebastiani P, Farrell JJ, Alsultan A, Wang S, Edward HL, Shappell H, Bae H, Milton JN, Baldwin CT, Al-Rubaish AM, Naserullah Z, Al-Muhanna F, Alsuliman A, Patra PK, Farrer LA, Ngo D, Vathipadiekal V, Chui DH, Al-Ali AK, Steinberg MH. BCL11A enhancer haplotypes and fetal hemoglobin in sickle cell anemia. Blood Cells Mol Dis. 2015 Mar; 54(3):224-30.View Related Profiles.

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Milton JN, Steinberg MH, Sebastiani P. Evaluation of an ensemble of genetic models for prediction of a quantitative trait. Front Genet. 2014; 5:474.View Related Profiles.

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Steinberg MH. Nitric oxide-based treatment for sickle cell leg ulcers? Lancet Haematol. 2014 Dec; 1(3):e86-7. PMID: 27029231; DOI: 10.1016/S2352-3026(14)00020-9;

Edward HL, Pisani LA, Rodriguez-Romero WE, Chaves-Villalobos J, Garcia-Quesada J, Harris NS, Luo HY, Steinberg MH, Forget BG, Chui DH. Hb Youngstown [ß101(G3)Glu???Ala; HBB: c.305A > C]: An unstable hemoglobin variant causing severe hemolytic anemia. Hemoglobin. 2014; 38(6):381-4.View Related Profiles.

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Buch K, Watanabe M, Elias EJ, Liao JH, Jara H, Nadgir RN, Saito N, Steinberg MH, Sakai O. Quantitative magnetic resonance imaging analysis of the lacrimal gland in sickle cell disease. J Comput Assist Tomogr. 2014 Sep-Oct; 38(5):674-80.View Related Profiles.

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Steinberg MH. More blood for sickle cell anemia? N Engl J Med. 2014 Aug 21; 371(8):775-6. PMID: 25140964; DOI: 10.1056/NEJMe1405776;

Griffin PJ, Sebastiani P, Edward H, Baldwin CT, Gladwin MT, Gordeuk VR, Chui DH, Steinberg MH. The genetics of hemoglobin A2 regulation in sickle cell anemia. Am J Hematol. 2014 Nov; 89(11):1019-23.View Related Profiles.

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Borgio JF, AbdulAzeez S, Al-Nafie AN, Naserullah ZA, Al-Jarrash S, Al-Madan MS, Al-Muhanna F, Steinberg MH, Al-Ali AK. A novel HBA2 gene conversion in cis or trans: "a12 allele" in a Saudi population. Blood Cells Mol Dis. 2014 Dec; 53(4):199-203. PMID: 25065854; DOI: 10.1016/j.bcmd.2014.07.001;

Klings ES, Machado RF, Morris CR, Gordeuk VR, Kato GJ, Ataga KI, Castro O, Hsu L, Telen MJ, Krishnamurti L, Steinberg MH, Gladwin MT. Reply: Practice guideline for pulmonary hypertension in sickle cell: direct evidence needed before universal adoption. Am J Respir Crit Care Med. 2014 Jul 15; 190(2):238-40.View Related Profiles.

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Calvaruso G, Vitrano A, Di Maggio R, Ballas S, Steinberg MH, Rigano P, Sacco M, Telfer P, Renda D, Barone R, Maggio A. Deferiprone versus deferoxamine in sickle cell disease: results from a 5-year long-term Italian multi-center randomized clinical trial. Blood Cells Mol Dis. 2014 Dec; 53(4):265-71. PMID: 24814618; DOI: 10.1016/j.bcmd.2014.04.004;

Ngo D, Steinberg M. Hematology clinic. Sickle cell disease. Hematology. 2014 Jun; 19(4):244-5.View Related Profiles.

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Klings ES, Machado RF, Barst RJ, Morris CR, Mubarak KK, Gordeuk VR, Kato GJ, Ataga KI, Gibbs JS, Castro O, Rosenzweig EB, Sood N, Hsu L, Wilson KC, Telen MJ, Decastro LM, Krishnamurti L, Steinberg MH, Badesch DB, Gladwin MT. An official American Thoracic Society clinical practice guideline: diagnosis, risk stratification, and management of pulmonary hypertension of sickle cell disease. Am J Respir Crit Care Med. 2014 Mar 15; 189(6):727-40.View Related Profiles.

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Milton JN, Gordeuk VR, Taylor JG, Gladwin MT, Steinberg MH, Sebastiani P. Prediction of fetal hemoglobin in sickle cell anemia using an ensemble of genetic risk prediction models. Circ Cardiovasc Genet. 2014 Apr; 7(2):110-5.View Related Profiles.

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PMID: 24585758; PMCID: PMC3994553; DOI: 10.1161/CIRCGENETICS.113.000387;

Zhang X, Zhang W, Ma SF, Desai AA, Saraf S, Miasniakova G, Sergueeva A, Ammosova T, Xu M, Nekhai S, Abbasi T, Casanova NG, Steinberg MH, Baldwin CT, Sebastiani P, Prchal JT, Kittles R, Garcia JG, Machado RF, Gordeuk VR. Hypoxic response contributes to altered gene expression and precapillary pulmonary hypertension in patients with sickle cell disease. Circulation. 2014 Apr 22; 129(16):1650-8.View Related Profiles.

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PMID: 24515990; PMCID: PMC4287376; DOI: 10.1161/CIRCULATIONAHA.113.005296;

Belfer I, Youngblood V, Darbari DS, Wang Z, Diaw L, Freeman L, Desai K, Dizon M, Allen D, Cunnington C, Channon KM, Milton J, Hartley SW, Nolan V, Kato GJ, Steinberg MH, Goldman D, Taylor JG. A GCH1 haplotype confers sex-specific susceptibility to pain crises and altered endothelial function in adults with sickle cell anemia. Am J Hematol. 2014 Feb; 89(2):187-93.View Related Profiles.

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Steinberg MH, Chui DH. HbC disorders. Blood. 2013 Nov 21; 122(22):3698.View Related Profiles.

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PMID: 24263962; DOI: 10.1182/blood-2013-09-526764;

Alsultan A, Alabdulaali MK, Griffin PJ, Alsuliman AM, Ghabbour HA, Sebastiani P, Albuali WH, Al-Ali AK, Chui DH, Steinberg MH. Sickle cell disease in Saudi Arabia: the phenotype in adults with the Arab-Indian haplotype is not benign. Br J Haematol. 2014 Feb; 164(4):597-604.View Related Profiles.

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PMID: 24224700; PMCID: PMC4094128; DOI: 10.1111/bjh.12650;

Steinberg MH, Chui DH, Dover GJ, Sebastiani P, Alsultan A. Fetal hemoglobin in sickle cell anemia: a glass half full? Blood. 2014 Jan 23; 123(4):481-5.View Related Profiles.

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PMID: 24222332; DOI: 10.1182/blood-2013-09-528067;

Pecoraro A, Rigano P, Troia A, Calzolari R, Scazzone C, Maggio A, Steinberg MH, Di Marzo R. Quantification of HBG mRNA in primary erythroid cultures: prediction of the response to hydroxyurea in sickle cell and beta-thalassemia. Eur J Haematol. 2014 Jan; 92(1):66-72. PMID: 24112139; DOI: 10.1111/ejh.12204;

Bhatnagar P, Barron-Casella E, Bean CJ, Milton JN, Baldwin CT, Steinberg MH, Debaun M, Casella JF, Arking DE. Genome-wide meta-analysis of systolic blood pressure in children with sickle cell disease. PLoS One. 2013; 8(9):e74193.View Related Profiles.

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Barbosa CG, Aleluia AC, Pacheco AP, Paz SS, Zanette AM, Lyra IM, Steinberg MH, Milton JN, Goncalves MS. Genetic modulation of HbF in Brazilians with HbSC disease and sickle cell anemia. Am J Hematol. 2013 Oct; 88(10):923-4.View Related Profiles.

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PMID: 23828430; PMCID: PMC3787949; DOI: 10.1002/ajh.23538;

Rigano P, Pecoraro A, Calvaruso G, Steinberg MH, Iannello S, Maggio A. Cerebrovascular events in sickle cell-beta thalassemia treated with hydroxyurea: a single center prospective survey in adult Italians. Am J Hematol. 2013 Nov; 88(11):E261-4. PMID: 23828131; DOI: 10.1002/ajh.23531;

Smith BW, Rozelle SS, Leung A, Ubellacker J, Parks A, Nah SK, French D, Gadue P, Monti S, Chui DH, Steinberg MH, Frelinger AL, Michelson AD, Theberge R, McComb ME, Costello CE, Kotton DN, Mostoslavsky G, Sherr DH, Murphy GJ. The aryl hydrocarbon receptor directs hematopoietic progenitor cell expansion and differentiation. Blood. 2013 Jul 18; 122(3):376-85.View Related Profiles.

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PMID: 23723449; PMCID: PMC3716202; DOI: 10.1182/blood-2012-11-466722;

Alsultan A, Ngo D, Bae H, Sebastiani P, Baldwin CT, Melista E, Suliman AM, Albuali WH, Nasserullah Z, Luo HY, Chui DH, Steinberg MH, Al-Ali AK. Genetic studies of fetal hemoglobin in the Arab-Indian haplotype sickle cell-ß(0) thalassemia. Am J Hematol. 2013 Jun; 88(6):531-2.View Related Profiles.

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PMID: 23483609; DOI: 10.1002/ajh.23434;

Ngo D, Bae H, Steinberg MH, Sebastiani P, Solovieff N, Baldwin CT, Melista E, Safaya S, Farrer LA, Al-Suliman AM, Albuali WH, Al Bagshi MH, Naserullah Z, Akinsheye I, Gallagher P, Luo HY, Chui DH, Farrell JJ, Al-Ali AK, Alsultan A. Fetal hemoglobin in sickle cell anemia: genetic studies of the Arab-Indian haplotype. Blood Cells Mol Dis. 2013 Jun; 51(1):22-6.View Related Profiles.

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PMID: 23465615; PMCID: PMC3647015; DOI: 10.1016/j.bcmd.2012.12.005;

Milton JN, Rooks H, Drasar E, McCabe EL, Baldwin CT, Melista E, Gordeuk VR, Nouraie M, Kato GR, Minniti C, Taylor J, Campbell A, Luchtman-Jones L, Rana S, Castro O, Zhang Y, Thein SL, Sebastiani P, Gladwin MT, Steinberg MH. Genetic determinants of haemolysis in sickle cell anaemia. Br J Haematol. 2013 Apr; 161(2):270-8.View Related Profiles.

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Watanabe M, Saito N, Nadgir RN, Liao JH, Flower EN, Steinberg MH, Sakai O. Craniofacial bone infarcts in sickle cell disease: clinical and radiological manifestations. J Comput Assist Tomogr. 2013 Jan-Feb; 37(1):91-7.View Related Profiles.

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PMID: 23321839; DOI: 10.1097/RCT.0b013e3182752967;

Liao J, Saito N, Ozonoff A, Jara H, Steinberg M, Sakai O. Quantitative MRI analysis of salivary glands in sickle cell disease. Dentomaxillofac Radiol. 2012 Dec; 41(8):630-6.View Related Profiles.

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PMID: 23166360; PMCID: PMC3528199; DOI: 10.1259/dmfr/31672000;

Liao JH, Jara H, Nadgir R, Elias E, Nowrouzi N, Saito N, Steinberg MH, Sakai O. qMRI relaxometry of mandibular bone marrow: a monomodal distribution in sickle cell disease. J Magn Reson Imaging. 2013 May; 37(5):1182-8.View Related Profiles.

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PMID: 23086731; DOI: 10.1002/jmri.23887;

Hartley SW, Monti S, Liu CT, Steinberg MH, Sebastiani P. Bayesian methods for multivariate modeling of pleiotropic SNP associations and genetic risk prediction. Front Genet. 2012; 3:176.View Related Profiles.

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PMID: 22973300; PMCID: PMC3438684; DOI: 10.3389/fgene.2012.00176;

Bae HT, Baldwin CT, Sebastiani P, Telen MJ, Ashley-Koch A, Garrett M, Hooper WC, Bean CJ, Debaun MR, Arking DE, Bhatnagar P, Casella JF, Keefer JR, Barron-Casella E, Gordeuk V, Kato GJ, Minniti C, Taylor J, Campbell A, Luchtman-Jones L, Hoppe C, Gladwin MT, Zhang Y, Steinberg MH. Meta-analysis of 2040 sickle cell anemia patients: BCL11A and HBS1L-MYB are the major modifiers of HbF in African Americans. Blood. 2012 Aug 30; 120(9):1961-2.View Related Profiles.

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PMID: 22936743; PMCID: PMC3433099; DOI: 10.1182/blood-2012-06-432849;

Elias EJ, Liao JH, Jara H, Watanabe M, Nadgir RN, Sakai Y, Erbay K, Saito N, Ozonoff A, Steinberg MH, Sakai O. Quantitative MRI analysis of craniofacial bone marrow in patients with sickle cell disease. AJNR Am J Neuroradiol. 2013 Mar; 34(3):622-7.View Related Profiles.

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PMID: 22878006; PMCID: PMC7964925; DOI: 10.3174/ajnr.A3240;

Alsultan A, Ngo DA, Farrell JJ, Akinsheye I, Solovieff N, Ghabbour HA, Al-Ali A, Alsuliman A, Al-Baghshi M, Albu-Ali W, Alabdulaali M, Baldwin CT, Farrer LA, Luo H, Melista E, Safaya S, Nwaru M, Chui DH, Steinberg MH. A functional promoter polymorphism of the d-globin gene is a specific marker of the Arab-Indian haplotype. Am J Hematol. 2012 Aug; 87(8):824-6.View Related Profiles.

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PMID: 22641398; PMCID: PMC4562292; DOI: 10.1002/ajh.23232;

Milton JN, Sebastiani P, Solovieff N, Hartley SW, Bhatnagar P, Arking DE, Dworkis DA, Casella JF, Barron-Casella E, Bean CJ, Hooper WC, DeBaun MR, Garrett ME, Soldano K, Telen MJ, Ashley-Koch A, Gladwin MT, Baldwin CT, Steinberg MH, Klings ES. A genome-wide association study of total bilirubin and cholelithiasis risk in sickle cell anemia. PLoS One. 2012; 7(4):e34741.View Related Profiles.

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PMID: 22558097; PMCID: PMC3338756; DOI: 10.1371/journal.pone.0034741;

Goldsmith JC, Bonham VL, Joiner CH, Kato GJ, Noonan AS, Steinberg MH. Framing the research agenda for sickle cell trait: building on the current understanding of clinical events and their potential implications. Am J Hematol. 2012 Mar; 87(3):340-6. PMID: 22307997; PMCID: PMC3513289; DOI: 10.1002/ajh.22271;

Verhovsek M, Shah NR, Wilcox I, Koenig SC, Barros T, Thornburg CD, Steinberg MH, Luo HY, Chui DH. Severe fetal and neonatal hemolytic anemia due to a 198 kb deletion removing the complete ß-globin gene cluster. Pediatr Blood Cancer. 2012 Nov; 59(5):941-4.View Related Profiles.

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Safaya S, Steinberg MH, Klings ES. Monocytes from sickle cell disease patients induce differential pulmonary endothelial gene expression via activation of NF-?B signaling pathway. Mol Immunol. 2012 Feb; 50(1-2):117-23.View Related Profiles.

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Sebastiani P, Solovieff N, Dewan AT, Walsh KM, Puca A, Hartley SW, Melista E, Andersen S, Dworkis DA, Wilk JB, Myers RH, Steinberg MH, Montano M, Baldwin CT, Hoh J, Perls TT. Genetic signatures of exceptional longevity in humans. PLoS One. 2012; 7(1):e29848.View Related Profiles.

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Sebastiani P, Riva A, Montano M, Pham P, Torkamani A, Scherba E, Benson G, Milton JN, Baldwin CT, Andersen S, Schork NJ, Steinberg MH, Perls TT. Whole genome sequences of a male and female supercentenarian, ages greater than 114?years. Front Genet. 2011; 2:90.View Related Profiles.

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Akinsheye I, Solovieff N, Ngo D, Malek A, Sebastiani P, Steinberg MH, Chui DH. Fetal hemoglobin in sickle cell anemia: molecular characterization of the unusually high fetal hemoglobin phenotype in African Americans. Am J Hematol. 2012 Feb; 87(2):217-9.View Related Profiles.

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Verhovsek M, So CC, O'Shea T, Gibney GT, Ma ES, Steinberg MH, Chui DH. Is HbA2 level a reliable diagnostic measurement for ß-thalassemia trait in people with iron deficiency? Am J Hematol. 2012 Jan; 87(1):114-6.View Related Profiles.

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Ngo DA, Aygun B, Akinsheye I, Hankins JS, Bhan I, Luo HY, Steinberg MH, Chui DH. Fetal haemoglobin levels and haematological characteristics of compound heterozygotes for haemoglobin S and deletional hereditary persistence of fetal haemoglobin. Br J Haematol. 2012 Jan; 156(2):259-64.View Related Profiles.

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Saito N, Watanabe M, Liao J, Flower EN, Nadgir RN, Steinberg MH, Sakai O. Clinical and radiologic findings of inner ear involvement in sickle cell disease. AJNR Am J Neuroradiol. 2011 Dec; 32(11):2160-4.View Related Profiles.

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Sakai, Osamu

PMID: 21960497; PMCID: PMC7964392; DOI: 10.3174/ajnr.A2720;

Steinberg MH. In the clinic. Sickle cell disease. Ann Intern Med. 2011 Sep 6; 155(5):ITC31-15; quiz ITC316. PMID: 21893620; DOI: 10.1059/0003-4819-155-5-201109060-01003;

Sebastiani P, Solovieff N, Puca A, Hartley SW, Melista E, Andersen S, Dworkis DA, Wilk JB, Myers RH, Steinberg MH, Montano M, Baldwin CT, Perls TT. Retraction. Science. 2011 Jul 22; 333(6041):404.View Related Profiles.

Baldwin, Clinton
Steinberg, Martin
Sebastiani, Paola
Myers, Richard
Andersen, Stacy
Perls, Thomas

PMID: 21778381; DOI: 10.1126/science.333.6041.404-a;

Castro OL, Gordeuk VR, Gladwin MT, Steinberg MH. Senicapoc trial results support the existence of different sub-phenotypes of sickle cell disease with possible drug-induced phenotypic shifts. Br J Haematol. 2011 Dec; 155(5):636-8. PMID: 21732927; DOI: 10.1111/j.1365-2141.2011.08758.x;

Alsultan A, Solovieff N, Aleem A, AlGahtani FH, Al-Shehri A, Osman ME, Kurban K, Bahakim H, Al-Momen AK, Baldwin CT, Chui DH, Steinberg MH. Fetal hemoglobin in sickle cell anemia: Saudi patients from the Southwestern province have similar HBB haplotypes but higher HbF levels than African Americans. Am J Hematol. 2011 Jul; 86(7):612-4.View Related Profiles.

Baldwin, Clinton
Chui, David
Steinberg, Martin

PMID: 21630302; DOI: 10.1002/ajh.22032;

Solovieff N, Hartley SW, Baldwin CT, Klings ES, Gladwin MT, Taylor JG, Kato GJ, Farrer LA, Steinberg MH, Sebastiani P. Ancestry of African Americans with sickle cell disease. Blood Cells Mol Dis. 2011 Jun 15; 47(1):41-5.View Related Profiles.

Baldwin, Clinton
Klings, Elizabeth
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PMID: 21546286; PMCID: PMC3116635; DOI: 10.1016/j.bcmd.2011.04.002;

Akinsheye I, Alsultan A, Solovieff N, Ngo D, Baldwin CT, Sebastiani P, Chui DH, Steinberg MH. Fetal hemoglobin in sickle cell anemia. Blood. 2011 Jul 7; 118(1):19-27.View Related Profiles.

Baldwin, Clinton
Chui, David
Ngo, Duyen
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PMID: 21490337; PMCID: PMC3139383; DOI: 10.1182/blood-2011-03-325258;

Smith WR, Ballas SK, McCarthy WF, Bauserman RL, Swerdlow PS, Steinberg MH, Waclawiw MA. The association between hydroxyurea treatment and pain intensity, analgesic use, and utilization in ambulatory sickle cell anemia patients. Pain Med. 2011 May; 12(5):697-705. PMID: 21481164; PMCID: PMC6818651; DOI: 10.1111/j.1526-4637.2011.01096.x;

Farrell JJ, Sherva RM, Chen ZY, Luo HY, Chu BF, Ha SY, Li CK, Lee AC, Li RC, Li CK, Yuen HL, So JC, Ma ES, Chan LC, Chan V, Sebastiani P, Farrer LA, Baldwin CT, Steinberg MH, Chui DH. A 3-bp deletion in the HBS1L-MYB intergenic region on chromosome 6q23 is associated with HbF expression. Blood. 2011 May 5; 117(18):4935-45.View Related Profiles.

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Sebastiani, Paola
Sherva, Richard

PMID: 21385855; PMCID: PMC3100700; DOI: 10.1182/blood-2010-11-317081;

Miller ST, Milton J, Steinberg MH. G6PD deficiency and stroke in the CSSCD. Am J Hematol. 2011 Mar; 86(3):331.View Related Profiles.

Hicks, Jacqueline
Steinberg, Martin

PMID: 21328436; DOI: 10.1002/ajh.21958;

Dworkis DA, Klings ES, Solovieff N, Li G, Milton JN, Hartley SW, Melista E, Parente J, Sebastiani P, Steinberg MH, Baldwin CT. Severe sickle cell anemia is associated with increased plasma levels of TNF-R1 and VCAM-1. Am J Hematol. 2011 Feb; 86(2):220-3.View Related Profiles.

Baldwin, Clinton
Klings, Elizabeth
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PMID: 21264913; PMCID: PMC3078643; DOI: 10.1002/ajh.21928;

Wang W, Brugnara C, Snyder C, Wynn L, Rogers Z, Kalinyak K, Brown C, Qureshi A, Bigelow C, Neumayr L, Smith-Whitley K, Chui DH, Delahunty M, Woolson R, Steinberg M, Telen M, Kesler K. The effects of hydroxycarbamide and magnesium on haemoglobin SC disease: results of the multi-centre CHAMPS trial. Br J Haematol. 2011 Mar; 152(6):771-6.View Related Profiles.

Chui, David
Steinberg, Martin

PMID: 21275961; DOI: 10.1111/j.1365-2141.2010.08523.x;

Solovieff N, Hartley SW, Baldwin CT, Perls TT, Steinberg MH, Sebastiani P. Clustering by genetic ancestry using genome-wide SNP data. BMC Genet. 2010; 11:108.View Related Profiles.

Baldwin, Clinton
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PMID: 21143920; PMCID: PMC3018397; DOI: 10.1186/1471-2156-11-108;

Verhovsek M, Henderson MP, Cox G, Luo HY, Steinberg MH, Chui DH. Unexpectedly low pulse oximetry measurements associated with variant hemoglobins: a systematic review. Am J Hematol. 2010 Nov; 85(11):882-5.View Related Profiles.

Chui, David
Luo, Hong
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PMID: 20890907; DOI: 10.1002/ajh.21810;

Minniti CP, Eckman J, Sebastiani P, Steinberg MH, Ballas SK. Leg ulcers in sickle cell disease. Am J Hematol. 2010 Oct; 85(10):831-3.View Related Profiles.

Steinberg, Martin
Sebastiani, Paola

PMID: 20872960; PMCID: PMC2953786; DOI: 10.1002/ajh.21838;

Gladwin MT, Barst RJ, Castro OL, Gordeuk VR, Hillery CA, Kato GJ, Kim-Shapiro DB, Machado R, Morris CR, Steinberg MH, Vichinsky EP. Pulmonary hypertension and NO in sickle cell. Blood. 2010 Aug 5; 116(5):852-4. PMID: 20688967; PMCID: PMC2918336; DOI: 10.1182/blood-2010-04-282095;

Sebastiani P, Solovieff N, Puca A, Hartley SW, Melista E, Andersen S, Dworkis DA, Wilk JB, Myers RH, Steinberg MH, Montano M, Baldwin CT, Perls TT. Genetic signatures of exceptional longevity in humans. Science. 2010 Jul 1; 2010.View Related Profiles.

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Steinberg, Martin
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Perls, Thomas

PMID: 20595579; DOI: 10.1126/science.1190532;

Steinberg MH, McCarthy WF, Castro O, Ballas SK, Armstrong FD, Smith W, Ataga K, Swerdlow P, Kutlar A, DeCastro L, Waclawiw MA. The risks and benefits of long-term use of hydroxyurea in sickle cell anemia: A 17.5 year follow-up. Am J Hematol. 2010 Jun; 85(6):403-8. PMID: 20513116; PMCID: PMC2879711; DOI: 10.1002/ajh.21699;

Rao V, Rosenberg P, Miles QS, Patadia D, Treiber K, Bertrand M, Norton M, Steinberg M, Tschanz J, Lyketsos C. Neuropsychiatric symptoms in dementia patients with and without a history of traumatic brain injury. J Neuropsychiatry Clin Neurosci. 2010; 22(2):166-72. PMID: 20463110; PMCID: PMC2928219; DOI: 10.1176/appi.neuropsych.22.2.166;

Sebastiani P, Solovieff N, Hartley SW, Milton JN, Riva A, Dworkis DA, Melista E, Klings ES, Garrett ME, Telen MJ, Ashley-Koch A, Baldwin CT, Steinberg MH. Genetic modifiers of the severity of sickle cell anemia identified through a genome-wide association study. Am J Hematol. 2010 Jan; 85(1):29-35.View Related Profiles.

Baldwin, Clinton
Klings, Elizabeth
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Steinberg, Martin
Sebastiani, Paola

PMID: 20029952; PMCID: PMC2903007; DOI: 10.1002/ajh.21572;

Solovieff N, Milton JN, Hartley SW, Sherva R, Sebastiani P, Dworkis DA, Klings ES, Farrer LA, Garrett ME, Ashley-Koch A, Telen MJ, Fucharoen S, Ha SY, Li CK, Chui DH, Baldwin CT, Steinberg MH. Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5' olfactory receptor gene cluster. Blood. 2010 Mar 4; 115(9):1815-22.View Related Profiles.

Baldwin, Clinton
Chui, David
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Hicks, Jacqueline
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Sebastiani, Paola
Sherva, Richard

PMID: 20018918; PMCID: PMC2832816; DOI: 10.1182/blood-2009-08-239517;

Sebastiani P, Montano M, Puca A, Solovieff N, Kojima T, Wang MC, Melista E, Meltzer M, Fischer SE, Andersen S, Hartley SH, Sedgewick A, Arai Y, Bergman A, Barzilai N, Terry DF, Riva A, Anselmi CV, Malovini A, Kitamoto A, Sawabe M, Arai T, Gondo Y, Steinberg MH, Hirose N, Atzmon G, Ruvkun G, Baldwin CT, Perls TT. RNA editing genes associated with extreme old age in humans and with lifespan in C. elegans. PLoS One. 2009; 4(12):e8210.View Related Profiles.

Baldwin, Clinton
Terry, Dellara
Steinberg, Martin
Montano, Monty
Sebastiani, Paola
Andersen, Stacy
Perls, Thomas

PMID: 20011587; PMCID: PMC2788130; DOI: 10.1371/journal.pone.0008210;

Koenig SC, Becirevic E, Hellberg MS, Li MY, So JC, Hankins JS, Ware RE, McMahon L, Steinberg MH, Luo HY, Chui DH. Sickle cell disease caused by heterozygosity for Hb S and novel LCR deletion: Report of two patients. Am J Hematol. 2009 Sep; 84(9):603-6.View Related Profiles.

Chui, David
Luo, Hong
Steinberg, Martin

PMID: 19650141; DOI: 10.1002/ajh.21480;

Kato GJ, Hebbel RP, Steinberg MH, Gladwin MT. Vasculopathy in sickle cell disease: Biology, pathophysiology, genetics, translational medicine, and new research directions. Am J Hematol. 2009 Sep; 84(9):618-25. PMID: 19610078; PMCID: PMC3209715; DOI: 10.1002/ajh.21475;

Smith WR, Bauserman RL, Ballas SK, McCarthy WF, Steinberg MH, Swerdlow PS, Waclawiw MA, Barton BA. Climatic and geographic temporal patterns of pain in the Multicenter Study of Hydroxyurea. Pain. 2009 Nov; 146(1-2):91-8. PMID: 19683393; DOI: 10.1016/j.pain.2009.07.008;

Sebastiani P, Timofeev N, Dworkis DA, Perls TT, Steinberg MH. Genome-wide association studies and the genetic dissection of complex traits. Am J Hematol. 2009 Aug; 84(8):504-15.View Related Profiles.

Steinberg, Martin
Sebastiani, Paola
Perls, Thomas

PMID: 19569043; PMCID: PMC2895326; DOI: 10.1002/ajh.21440;

Thornburg CD, Steinberg MH, Chui DH. Hemoglobin SE disease in Maine, and severe thalassemia in New Hampshire. J Pediatr Hematol Oncol. 2009 Apr; 31(4):307.View Related Profiles.

Chui, David
Steinberg, Martin

PMID: 19346889; DOI: 10.1097/MPH.0b013e31819af9db;

Safaya S, Klings ES, Odhiambo A, Li G, Farber HW, Steinberg MH. Effect of sodium butyrate on lung vascular TNFSF15 (TL1A) expression: differential expression patterns in pulmonary artery and microvascular endothelial cells. Cytokine. 2009 Apr; 46(1):72-8.View Related Profiles.

Klings, Elizabeth
Farber, Harrison
Steinberg, Martin

PMID: 19251437; PMCID: PMC2702851; DOI: 10.1016/j.cyto.2008.12.013;

Chen Z, Luo HY, Steinberg MH, Chui DH. BCL11A represses HBG transcription in K562 cells. Blood Cells Mol Dis. 2009 Mar-Apr; 42(2):144-9.View Related Profiles.

Chui, David
Luo, Hong
Steinberg, Martin

PMID: 19153051; DOI: 10.1016/j.bcmd.2008.12.003;

Steinberg MH. Genetic etiologies for phenotypic diversity in sickle cell anemia. ScientificWorldJournal. 2009; 9:46-67. PMID: 19151898; PMCID: PMC5823205; DOI: 10.1100/tsw.2009.10;

Wilcox I, Boettger K, Greene L, Malek A, Davis L, Steinberg MH, Luo HY, Chui DH. Hemoglobin Kenya composed of alpha- and ((A)gammabeta)-fusion-globin chains, associated with hereditary persistence of fetal hemoglobin. Am J Hematol. 2009 Jan; 84(1):55-8.View Related Profiles.

Malek, Anita
Chui, David
Luo, Hong
Steinberg, Martin

PMID: 19006227; DOI: 10.1002/ajh.21308;

Steinberg MH, Forget BG, Higgs DR, Weatherall DJ eds. Disorders of Hemoglobin: Genetics, Pathophysiology, Clinical Management, 2nd ed. Cambridge University Press. Cambridge. 2009; 826.

Steinberg MH. Sickle cell anemia, the first molecular disease: overview of molecular etiology, pathophysiology, and therapeutic approaches. ScientificWorldJournal. 2008; 8:1295-324. PMID: 19112541; PMCID: PMC5848659; DOI: 10.1100/tsw.2008.157;

Zhao Z, Timofeev N, Hartley SW, Chui DH, Fucharoen S, Perls TT, Steinberg MH, Baldwin CT, Sebastiani P. Imputation of missing genotypes: an empirical evaluation of IMPUTE. BMC Genet. 2008; 9:85.View Related Profiles.

Baldwin, Clinton
Chui, David
Steinberg, Martin
Sebastiani, Paola
Perls, Thomas

PMID: 19077279; PMCID: PMC2636842; DOI: 10.1186/1471-2156-9-85;

Nolan VG, Zhang Y, Lash T, Sebastiani P, Steinberg MH. Association between wind speed and the occurrence of sickle cell acute painful episodes: results of a case-crossover study. Br J Haematol. 2008 Nov; 143(3):433-8.View Related Profiles.

Steinberg, Martin
Sebastiani, Paola
Zhang, Yuqing

PMID: 18729854; PMCID: PMC4347894; DOI: 10.1111/j.1365-2141.2008.07354.x;

Sedgewick AE, Timofeev N, Sebastiani P, So JC, Ma ES, Chan LC, Fucharoen G, Fucharoen S, Barbosa CG, Vardarajan BN, Farrer LA, Baldwin CT, Steinberg MH, Chui DH. BCL11A is a major HbF quantitative trait locus in three different populations with beta-hemoglobinopathies. Blood Cells Mol Dis. 2008 Nov-Dec; 41(3):255-8.View Related Profiles.

Baldwin, Clinton
Chui, David
Farrer, Lindsay
Steinberg, Martin
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PMID: 18691915; PMCID: PMC4100606; DOI: 10.1016/j.bcmd.2008.06.007;

Klings ES, Anton Bland D, Rosenman D, Princeton S, Odhiambo A, Li G, Bernard SA, Steinberg MH, Farber HW. Pulmonary arterial hypertension and left-sided heart disease in sickle cell disease: clinical characteristics and association with soluble adhesion molecule expression. Am J Hematol. 2008 Jul; 83(7):547-53.View Related Profiles.

Klings, Elizabeth
Farber, Harrison
Steinberg, Martin
Bernard, Sheilah

PMID: 18383329; DOI: 10.1002/ajh.21187;

Steinberg MH. SNPing away at sickle cell pathophysiology. Blood. 2008 Jun 15; 111(12):5420-1. PMID: 18544690; PMCID: PMC2424143; DOI: 10.1182/blood-2008-01-135392;

Gibney GT, Panhuysen CI, So JC, Ma ES, Ha SY, Li CK, Lee AC, Li CK, Yuen HL, Lau YL, Johnson DM, Farrell JJ, Bisbee AB, Farrer LA, Steinberg MH, Chan LC, Chui DH. Variation and heritability of Hb F and F-cells among beta-thalassemia heterozygotes in Hong Kong. Am J Hematol. 2008 Jun; 83(6):458-64.View Related Profiles.

Chui, David
Farrer, Lindsay
Steinberg, Martin

PMID: 18266208; DOI: 10.1002/ajh.21150;

Taylor JG, Nolan VG, Mendelsohn L, Kato GJ, Gladwin MT, Steinberg MH. Chronic hyper-hemolysis in sickle cell anemia: association of vascular complications and mortality with less frequent vasoocclusive pain. PLoS One. 2008; 3(5):e2095. PMID: 18461136; PMCID: PMC2330070; DOI: 10.1371/journal.pone.0002095;

Chen Z, Luo HY, Basran RK, Hsu TH, Mang DW, Nuntakarn L, Rosenfield CG, Patrinos GP, Hardison RC, Steinberg MH, Chui DH. A T-to-G transversion at nucleotide -567 upstream of HBG2 in a GATA-1 binding motif is associated with elevated hemoglobin F. Mol Cell Biol. 2008 Jul; 28(13):4386-93.View Related Profiles.

Chui, David
Luo, Hong
Steinberg, Martin
Basran, Raveen
Hsu, Tien

PMID: 18443038; PMCID: PMC2447137; DOI: 10.1128/MCB.00071-08;

Adewoye AH, Chen TC, Ma Q, McMahon L, Mathieu J, Malabanan A, Steinberg MH, Holick MF. Sickle cell bone disease: response to vitamin D and calcium. Am J Hematol. 2008 Apr; 83(4):271-4.View Related Profiles.

Malabanan, Alan
Steinberg, Martin
Holick, Michael
Chen, Tai

PMID: 17924548

Sebastiani P, Wang L, Nolan VG, Melista E, Ma Q, Baldwin CT, Steinberg MH. Fetal hemoglobin in sickle cell anemia: Bayesian modeling of genetic associations. Am J Hematol. 2008 Mar; 83(3):189-95.View Related Profiles.

Baldwin, Clinton
Steinberg, Martin
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PMID: 17918249

Sebastiani P, Zhao Z, Abad-Grau MM, Riva A, Hartley SW, Sedgewick AE, Doria A, Montano M, Melista E, Terry D, Perls TT, Steinberg MH, Baldwin CT. A hierarchical and modular approach to the discovery of robust associations in genome-wide association studies from pooled DNA samples. BMC Genet. 2008; 9:6.View Related Profiles.

Baldwin, Clinton
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PMID: 18194558; PMCID: PMC2248205; DOI: 10.1186/1471-2156-9-6;

Steinberg MH. Clinical trials in sickle cell disease: adopting the combination chemotherapy paradigm. Am J Hematol. 2008 Jan; 83(1):1-3. PMID: 17724701

Morris CR, Suh JH, Hagar W, Larkin S, Bland DA, Steinberg MH, Vichinsky EP, Shigenaga M, Ames B, Kuypers FA, Klings ES. Erythrocyte glutamine depletion, altered redox environment, and pulmonary hypertension in sickle cell disease. Blood. 2008 Jan 1; 111(1):402-10.View Related Profiles.

Klings, Elizabeth
Steinberg, Martin

PMID: 17848621; PMCID: PMC2200820; DOI: 10.1182/blood-2007-04-081703;

Masiello D, Heeney MM, Adewoye AH, Eung SH, Luo HY, Steinberg MH, Chui DH. Hemoglobin SE disease: a concise review. Am J Hematol. 2007 Jul; 82(7):643-9.View Related Profiles.

Chui, David
Steinberg, Martin

PMID: 17278112

Sebastiani P, Nolan VG, Baldwin CT, Abad-Grau MM, Wang L, Adewoye AH, McMahon LC, Farrer LA, Taylor JG, Kato GJ, Gladwin MT, Steinberg MH. A network model to predict the risk of death in sickle cell disease. Blood. 2007 Oct 1; 110(7):2727-35.View Related Profiles.

Baldwin, Clinton
Farrer, Lindsay
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PMID: 17600133; PMCID: PMC1988954; DOI: 10.1182/blood-2007-04-084921;

Adewoye AH, Nolan V, McMahon L, Ma Q, Steinberg MH. Effectiveness of a dedicated day hospital for management of acute sickle cell pain. Haematologica. 2007 Jun; 92(6):854-5. PMID: 17550862

Steinberg MH. Pneumococcus and sickle cell disease: the beginning of the end? Clin Infect Dis. 2007 Jun 1; 44(11):1434-5. PMID: 17479938

Nolan VG, Ma Q, Cohen HT, Adewoye A, Rybicki AC, Baldwin C, Mahabir RN, Homan EP, Wyszynski DF, Fabry ME, Nagel RL, Farrer LA, Steinberg MH. Estimated glomerular filtration rate in sickle cell anemia is associated with polymorphisms of bone morphogenetic protein receptor 1B. Am J Hematol. 2007 Mar; 82(3):179-84.View Related Profiles.

Baldwin, Clinton
Cohen, Herbert
Farrer, Lindsay
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PMID: 17034027

Ma Q, Wyszynski DF, Farrell JJ, Kutlar A, Farrer LA, Baldwin CT, Steinberg MH. Fetal hemoglobin in sickle cell anemia: genetic determinants of response to hydroxyurea. Pharmacogenomics J. 2007 Dec; 7(6):386-94.View Related Profiles.

Baldwin, Clinton
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PMID: 17299377

Luo HY, Adewoye AH, Pilichowska M, Li MY, Basran RK, Steinberg MH, Chui DH. Two new alpha-thalassemia frameshift mutations. Hemoglobin. 2007; 31(2):135-9.View Related Profiles.

Luo, Hong
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PMID: 17486494

Odhiambo A, Perlman DH, Huang H, Costello CE, Farber HW, Steinberg MH, McComb ME, Klings ES. Identification of oxidative post-translational modification of serum albumin in patients with idiopathic pulmonary arterial hypertension and pulmonary hypertension of sickle cell anemia. Rapid Commun Mass Spectrom. 2007; 21(14):2195-203.View Related Profiles.

Costello, Catherine
Klings, Elizabeth
Farber, Harrison
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PMID: 17569101

Kato GJ, Gladwin MT, Steinberg MH. Deconstructing sickle cell disease: reappraisal of the role of hemolysis in the development of clinical subphenotypes. Blood Rev. 2007 Jan; 21(1):37-47. PMID: 17084951; PMCID: PMC2048670; DOI: 10.1016/j.blre.2006.07.001;

Adewoye AH, Ramsey J, McMahon L, Sakai O, Steinberg MH. Lacrimal gland enlargement in sickle cell disease. Am J Hematol. 2006 Nov; 81(11):888-9.View Related Profiles.

Ramsey, Jean
Steinberg, Martin
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PMID: 16929543

Andersson BA, Wering ME, Luo HY, Basran RK, Steinberg MH, Smith HP, Chui DH. Sickle cell disease due to compound heterozygosity for Hb S and a novel 7.7-kb beta-globin gene deletion. Eur J Haematol. 2007 Jan; 78(1):82-5.View Related Profiles.

Chui, David
Smith, Hedy
Luo, Hong
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Basran, Raveen

PMID: 17038017

Machado RF, Anthi A, Steinberg MH, Bonds D, Sachdev V, Kato GJ, Taveira-DaSilva AM, Ballas SK, Blackwelder W, Xu X, Hunter L, Barton B, Waclawiw M, Castro O, Gladwin MT. N-terminal pro-brain natriuretic peptide levels and risk of death in sickle cell disease. JAMA. 2006 Jul 19; 296(3):310-8. PMID: 16849664

Adewoye AH, Nolan VG, Ma Q, Baldwin C, Wyszynski DF, Farrell JJ, Farrer LA, Steinberg MH. Association of polymorphisms of IGF1R and genes in the transforming growth factor- beta /bone morphogenetic protein pathway with bacteremia in sickle cell anemia. Clin Infect Dis. 2006 Sep 1; 43(5):593-8.View Related Profiles.

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PMID: 16886151

Nolan VG, Adewoye A, Baldwin C, Wang L, Ma Q, Wyszynski DF, Farrell JJ, Sebastiani P, Farrer LA, Steinberg MH. Sickle cell leg ulcers: associations with haemolysis and SNPs in Klotho, TEK and genes of the TGF-beta/BMP pathway. Br J Haematol. 2006 Jun; 133(5):570-8.View Related Profiles.

Baldwin, Clinton
Farrer, Lindsay
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PMID: 16681647; PMCID: PMC1679888; DOI: 10.1111/j.1365-2141.2006.06074.x;

Luo HY, Heeney M, Wang WC, Eung SH, Ware RE, Steinberg MH, Chui DH. Hemoglobinopathies mimicking Hb S/beta-thalassemia: Hb S/S with alpha-thalassemia and Hb S/Volga. Am J Hematol. 2006 May; 81(5):361-5.View Related Profiles.

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Luo, Hong
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PMID: 16628724

Steinberg MH, Adewoye AH. Modifier genes and sickle cell anemia. Curr Opin Hematol. 2006 May; 13(3):131-6. PMID: 16567954

Klings ES, Wyszynski DF, Nolan VG, Steinberg MH. Abnormal pulmonary function in adults with sickle cell anemia. Am J Respir Crit Care Med. 2006 Jun 1; 173(11):1264-9.View Related Profiles.

Klings, Elizabeth
Steinberg, Martin

PMID: 16556694; PMCID: PMC2662970; DOI: 10.1164/rccm.200601-125OC;

Steinberg MH. Pathophysiologically based drug treatment of sickle cell disease. Trends Pharmacol Sci. 2006 Apr; 27(4):204-10. PMID: 16530854

Law HY, Luo HY, Wang W, Ho JF, Najmabadi H, Ng IS, Steinberg MH, Chui DH, Chong SS. Determining the cause of patchwork HBA1 and HBA2 genes: recurrent gene conversion or crossing over fixation events. Haematologica. 2006 Mar; 91(3):297-302.View Related Profiles.

Chui, David
Steinberg, Martin

PMID: 16503550

Chui DH, Cunningham MJ, Luo HY, Wolfe LC, Neufeld EJ, Steinberg MH. Screening and counseling for thalassemia. Blood. 2006 Feb 15; 107(4):1735-7. PMID: 16461765; PMCID: PMC1895412; DOI: 10.1182/blood-2005-09-3557;

Luo HY, Tang W, Eung SH, Coad JE, Canfield P, Keller F, Crowell EH, Steinberg MH, Chui DH. Dominantly inherited beta thalassaemia intermedia caused by a new single nucleotide deletion in exon 2 of the beta globin gene: Hb morgantown (beta91 CTG>CG). J Clin Pathol. 2005 Oct; 58(10):1110-2.View Related Profiles.

Chui, David
Luo, Hong
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PMID: 16189162; PMCID: PMC1770750; DOI: 10.1136/jcp.2004.023010;

Nolan VG, Wyszynski DF, Farrer LA, Steinberg MH. Hemolysis-associated priapism in sickle cell disease. Blood. 2005 Nov 1; 106(9):3264-7.View Related Profiles.

Farrer, Lindsay
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PMID: 15985542; PMCID: PMC1283070; DOI: 10.1182/blood-2005-04-1594;

Luo HY, Boudreaux J, Steinberg MH, Chui DH. Patients with thalassemia in the United States. Blood. 2005 Jun 15; 105(12):4896-7.View Related Profiles.

Chui, David
Steinberg, Martin

PMID: 15933066; PMCID: PMC1894999; DOI: 10.1182/blood-2005-03-0856;

Steinberg MH. Predicting clinical severity in sickle cell anaemia. Br J Haematol. 2005 May; 129(4):465-81. PMID: 15877729

Baldwin C, Nolan VG, Wyszynski DF, Ma QL, Sebastiani P, Embury SH, Bisbee A, Farrell J, Farrer L, Steinberg MH. Association of klotho, bone morphogenic protein 6, and annexin A2 polymorphisms with sickle cell osteonecrosis. Blood. 2005 Jul 1; 106(1):372-5.View Related Profiles.

Baldwin, Clinton
Farrer, Lindsay
Steinberg, Martin
Sebastiani, Paola

PMID: 15784727; PMCID: PMC1895132; DOI: 10.1182/blood-2005-02-0548;

Sebastiani P, Ramoni MF, Nolan V, Baldwin CT, Steinberg MH. Genetic dissection and prognostic modeling of overt stroke in sickle cell anemia. Nat Genet. 2005 Apr; 37(4):435-40.View Related Profiles.

Baldwin, Clinton
Steinberg, Martin
Sebastiani, Paola

PMID: 15778708; PMCID: PMC2896308; DOI: 10.1038/ng1533;

Klings ES, Safaya S, Adewoye AH, Odhiambo A, Frampton G, Lenburg M, Gerry N, Sebastiani P, Steinberg MH, Farber HW. Differential gene expression in pulmonary artery endothelial cells exposed to sickle cell plasma. Physiol Genomics. 2005 May 11; 21(3):293-8.View Related Profiles.

Klings, Elizabeth
Farber, Harrison
Lenburg, Marc
Steinberg, Martin
Sebastiani, Paola

PMID: 15741505

Adewoye AH, Klings ES, Farber HW, Palaima E, Bausero MA, McMahon L, Odhiambo A, Surinder S, Yoder M, Steinberg MH, Asea A. Sickle cell vaso-occlusive crisis induces the release of circulating serum heat shock protein-70. Am J Hematol. 2005 Mar; 78(3):240-2.View Related Profiles.

Klings, Elizabeth
Farber, Harrison
Yoder, Mark
Steinberg, Martin

PMID: 15726596; PMCID: PMC1762099; DOI: 10.1002/ajh.20292;

Zandi PP, Sparks DL, Khachaturian AS, Tschanz J, Norton M, Steinberg M, Welsh-Bohmer KA, Breitner JC. Do statins reduce risk of incident dementia and Alzheimer disease? The Cache County Study. Arch Gen Psychiatry. 2005 Feb; 62(2):217-24. PMID: 15699299

Nolan VG, Baldwin C, Ma Q, Wyszynski DF, Amirault Y, Farrell JJ, Bisbee A, Embury SH, Farrer LA, Steinberg MH. Association of single nucleotide polymorphisms in klotho with priapism in sickle cell anaemia. Br J Haematol. 2005 Jan; 128(2):266-72.View Related Profiles.

Baldwin, Clinton
Farrer, Lindsay
Steinberg, Martin

PMID: 15638863

Luo HY, Irving I, Prior J, Lim E, Eung SH, Skelton TP, Erber WN, Steinberg MH, Chui DH. Hemoglobin Titusville, a low oxygen affinity variant hemoglobin, in a family of Northern European background. Am J Hematol. 2004 Dec; 77(4):384-6.View Related Profiles.

Luo, Hong
Steinberg, Martin

PMID: 15551405

Luo HY, Adewoye AH, Eung SH, Skelton TP, Quillen K, McMahon L, Steinberg MH, Chui DH. A novel sickle hemoglobin: hemoglobin S-south end. J Pediatr Hematol Oncol. 2004 Nov; 26(11):773-6.View Related Profiles.

Chui, David
Luo, Hong
Quillen, Karen
Steinberg, Martin

PMID: 15543018

Saleh M, Vaillancourt JP, Graham RK, Huyck M, Srinivasula SM, Alnemri ES, Steinberg MH, Nolan V, Baldwin CT, Hotchkiss RS, Buchman TG, Zehnbauer BA, Hayden MR, Farrer LA, Roy S, Nicholson DW. Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms. Nature. 2004 May 6; 429(6987):75-9.View Related Profiles.

Baldwin, Clinton
Farrer, Lindsay
Steinberg, Martin

PMID: 15129283

Wyszynski DF, Baldwin CT, Cleves MA, Amirault Y, Nolan VG, Farrell JJ, Bisbee A, Kutlar A, Farrer LA, Steinberg MH. Polymorphisms near a chromosome 6q QTL area are associated with modulation of fetal hemoglobin levels in sickle cell anemia. Cell Mol Biol (Noisy-le-grand). 2004 Feb; 50(1):23-33.View Related Profiles.

Baldwin, Clinton
Farrer, Lindsay
Steinberg, Martin

PMID: 15040424

Steinberg M, Tschanz JT, Corcoran C, Steffens DC, Norton MC, Lyketsos CG, Breitner JC. The persistence of neuropsychiatric symptoms in dementia: the Cache County Study. Int J Geriatr Psychiatry. 2004 Jan; 19(1):19-26. PMID: 14716695

Ingle J, Adewoye A, Dewan R, Okoli M, Rollins L, Eung SH, Luo HY, Chui DH, Steinberg MH. Hb Hope [beta136(H14)Gly-->Asp (GGT-->GAT)]: interactions with Hb S [beta6(A3)Glu-->Val (GAG-->GTG)], other variant hemoglobins and thalassemia. Hemoglobin. 2004; 28(4):277-85.View Related Profiles.

Luo, Hong
Steinberg, Martin

PMID: 15658184

Buchanan GR, DeBaun MR, Quinn CT, Steinberg MH. Sickle cell disease. Hematology Am Soc Hematol Educ Program. 2004; 35-47. PMID: 15561675

Eberhardt RT, McMahon L, Duffy SJ, Steinberg MH, Perrine SP, Loscalzo J, Coffman JD, Vita JA. Sickle cell anemia is associated with reduced nitric oxide bioactivity in peripheral conduit and resistance vessels. Am J Hematol. 2003 Oct; 74(2):104-11.View Related Profiles.

Vita, Joseph
Steinberg, Martin
Eberhardt, Robert
Perrine-Faller, Susan

PMID: 14508796

Nagel RL, Fabry ME, Steinberg MH. The paradox of hemoglobin SC disease. Blood Rev. 2003 Sep; 17(3):167-78. PMID: 12818227

Steinberg MH. Bone marrow transplantation in sickle cell disease: indications and successes. Clin Adv Hematol Oncol. 2003 Jul; 1(7):406-7. PMID: 16258422

Steinberg MH, Barton F, Castro O, Pegelow CH, Ballas SK, Kutlar A, Orringer E, Bellevue R, Olivieri N, Eckman J, Varma M, Ramirez G, Adler B, Smith W, Carlos T, Ataga K, DeCastro L, Bigelow C, Saunthararajah Y, Telfer M, Vichinsky E, Claster S, Shurin S, Bridges K, Waclawiw M, Bonds D, Terrin M. Effect of hydroxyurea on mortality and morbidity in adult sickle cell anemia: risks and benefits up to 9 years of treatment. JAMA. 2003 Apr 2; 289(13):1645-51. PMID: 12672732

Steinberg MH. Therapies to increase fetal hemoglobin in sickle cell disease. Curr Hematol Rep. 2003 Mar; 2(2):95-101. PMID: 12901139

Steinberg MH, Voskaridou E, Kutlar A, Loukopoulos D, Koshy M, Ballas SK, Castro O, Barton F. Concordant fetal hemoglobin response to hydroxyurea in siblings with sickle cell disease. Am J Hematol. 2003 Feb; 72(2):121-6. PMID: 12555216

Steinberg MH. Hydroxyurea treatment for sickle cell disease. ScientificWorldJournal. 2002 Jun 25; 2:1706-28. PMID: 12806165

Steinberg MH, Brugnara C. Developing treatment for sickle cell disease. Expert Opin Investig Drugs. 2002 May; 11(5):645-59. PMID: 11996646

Steinberg MH, Brugnara C. Pathophysiological-based approaches to treatment of sickle cell disease. Annu Rev Med. 2003; 54:89-112. PMID: 12359829

Orringer EP, Casella JF, Ataga KI, Koshy M, Adams-Graves P, Luchtman-Jones L, Wun T, Watanabe M, Shafer F, Kutlar A, Abboud M, Steinberg M, Adler B, Swerdlow P, Terregino C, Saccente S, Files B, Ballas S, Brown R, Wojtowicz-Praga S, Grindel JM. Purified poloxamer 188 for treatment of acute vaso-occlusive crisis of sickle cell disease: A randomized controlled trial. JAMA. 2001 Nov 7; 286(17):2099-106. PMID: 11694150

Steinberg MH, Rodgers GP. Pathophysiology of sickle cell disease: role of cellular and genetic modifiers. Semin Hematol. 2001 Oct; 38(4):299-306. PMID: 11605164

Steinberg MH, Rodgers GP. Pharmacologic modulation of fetal hemoglobin. Medicine (Baltimore). 2001 Sep; 80(5):328-44. PMID: 11552087

Steinberg MH. Modulation of fetal hemoglobin in sickle cell anemia. Hemoglobin. 2001 May; 25(2):195-211. PMID: 11480781

Nagel RL, Steinberg MH. Role of epistatic (modifier) genes in the modulation of the phenotypic diversity of sickle cell anemia. Pediatr Pathol Mol Med. 2001 Mar-Apr; 20(2):123-36. PMID: 12673837

Qu G, Elkins S, Steinberg MH. Thalassemia intermedia and extramedullary hematopoiesis associated with compound heterozygosity for the 532 bp deletion of the beta-globin gene and gene deletion hereditary persistence of fetal hemoglobin. Hemoglobin. 2001 Feb; 25(1):91-6. PMID: 11300354

Steinberg MH, Forget BG, Higgs D, Nagel RL eds. Disorders of Hemoglobin: Genetics, Pathophysiology, Clinical Management. Cambridge University Press. Cambridge. 2001; 1268.

Mitchell T, Plonczynski M, McCollum A, Hardy CL, Safaya S, Steinberg MH. Gene expression profiling during erythroid differentiation of K562 cells. Blood Cells Mol Dis. 2001 Jan-Feb; 27(1):309-19. PMID: 11358393

Steinberg MH. Southern Society for Clinical Investigation Founders Medal recipient's address. Am J Med Sci. 2000 Sep; 320(3):161-2. PMID: 11014369

Kopetz S, Steele CD, Brandt J, Baker A, Kronberg M, Galik E, Steinberg M, Warren A, Lyketsos CG. Characteristics and outcomes of dementia residents in an assisted living facility. Int J Geriatr Psychiatry. 2000 Jul; 15(7):586-93. PMID: 10918338

Iyer R, Baliga R, Nagel RL, Brugnara C, Kirchner K, Hogan S, Steinberg MH. Maximum urine concentrating ability in children with Hb SC disease: effects of hydroxyurea. Am J Hematol. 2000 May; 64(1):47-52. PMID: 10815787

Swedberg K, Bergh CH, Dickstein K, McNay J, Steinberg M. The effects of moxonidine, a novel imidazoline, on plasma norepinephrine in patients with congestive heart failure. Moxonidine Investigators. J Am Coll Cardiol. 2000 Feb; 35(2):398-404. PMID: 10676687

Rosse WF, Narla M, Petz LD, Steinberg MH. New Views of Sickle Cell Disease Pathophysiology and Treatment. Hematology Am Soc Hematol Educ Program. 2000; 2-17. PMID: 11701532

Steinberg MH, Mitchell TE. Novel approaches to treatment of sickle cell anaemia. Expert Opin Investig Drugs. 1999 Nov; 8(11):1823-1836. PMID: 11139827; DOI: 10.1517/13543784.8.11.1823;

Plonczynski M, Hardy CL, Safaya S, Harrell A, McCoy L, Brinson A, Agwarangbo L, Steinberg MH. Induction of globin synthesis in K562 cells is associated with differential expression of transcription factor genes. Blood Cells Mol Dis. 1999 Jun-Aug; 25(3-4):156-65. PMID: 10575541

Belcher JD, Marker PH, Geiger P, Girotti AW, Steinberg MH, Hebbel RP, Vercellotti GM. Low-density lipoprotein susceptibility to oxidation and cytotoxicity to endothelium in sickle cell anemia. J Lab Clin Med. 1999 Jun; 133(6):605-12. PMID: 10360636

Solovey A, Gui L, Ramakrishnan S, Steinberg MH, Hebbel RP. Sickle cell anemia as a possible state of enhanced anti-apoptotic tone: survival effect of vascular endothelial growth factor on circulating and unanchored endothelial cells. Blood. 1999 Jun 1; 93(11):3824-30. PMID: 10339489

Rhodes SL, Plonczynski M, Harrell A, Li J, Safaya S, Files JC, Steinberg MH. Double heterozygosity for the codon beta 39 C-to-T nonsense mutation and a triplicate alpha-globin gene locus can cause "dominantly" inherited beta-thalassemia intermedia. Am J Med Sci. 1999 May; 317(5):341-5. PMID: 10334122

Steinberg MH. Management of sickle cell disease. N Engl J Med. 1999 Apr 1; 340(13):1021-30. PMID: 10099145

Li J, Wilson D, Plonczynski M, Harrell A, Cook CB, Scheer WD, Zeng YT, Coleman MB, Steinberg MH. Genetic studies suggest a multicentric origin for Hb G-Coushatta [beta22(B4)Glu-->Ala]. Hemoglobin. 1999 Feb; 23(1):57-67. PMID: 10081986

Steinberg MH, Lu ZH, Nagel RL, Venkataramani S, Milner PF, Huey L, Safaya S, Rieder RF. Hematological effects of atypical and Cameroon beta-globin gene haplotypes in adult sickle cell anemia. Am J Hematol. 1998 Oct; 59(2):121-6. PMID: 9766796

Li J, Plonczynski M, Steinberg MH, Kheradpour A, Alter BP. Severe Hb S-beta+ thalassemia caused by IVS-I splice site mutations. Hemoglobin. 1998 Jul; 22(4):383-6. PMID: 9730369

Steinberg MH. Pathophysiology of sickle cell disease. Baillieres Clin Haematol. 1998 Mar; 11(1):163-84. PMID: 10872477

Steinberg MH, Nagel RL, Brugnara C. Cellular effects of hydroxyurea in Hb SC disease. Br J Haematol. 1997 Sep; 98(4):838-44. PMID: 9326175

Adams-Graves P, Kedar A, Koshy M, Steinberg M, Veith R, Ward D, Crawford R, Edwards S, Bustrack J, Emanuele M. RheothRx (poloxamer 188) injection for the acute painful episode of sickle cell disease: a pilot study. Blood. 1997 Sep 1; 90(5):2041-6. PMID: 9292541

Figueiredo MS, Steinberg MH. Fetal hemoglobin in sickle cell anemia: examination of phylogenetically conserved sequences within the locus control region but outside the cores of hypersensitive sites 2 and 3. Blood Cells Mol Dis. 1997 Aug; 23(2):188-200. PMID: 9236157

Steinberg MH. Determinants of fetal hemoglobin response to hydroxyurea. Semin Hematol. 1997 Jul; 34(3 Suppl 3):8-14. PMID: 9317196

Merritt D, Jones RT, Head C, Thibodeau SN, Fairbanks VF, Steinberg MH, Coleman MB, Rodgers GP. Hb Seal Rock [(alpha 2)142 term-->Glu, codon 142 TAA-->GAA]: an extended alpha chain variant associated with anemia, microcytosis, and alpha-thalassemia-2 (-3.7 Kb). Hemoglobin. 1997 Jul; 21(4):331-44. PMID: 9255612

Steinberg MH, Lu ZH, Barton FB, Terrin ML, Charache S, Dover GJ. Fetal hemoglobin in sickle cell anemia: determinants of response to hydroxyurea. Multicenter Study of Hydroxyurea. Blood. 1997 Feb 1; 89(3):1078-88. PMID: 9028341

Pegelow CH, Colangelo L, Steinberg M, Wright EC, Smith J, Phillips G, Vichinsky E. Natural history of blood pressure in sickle cell disease: risks for stroke and death associated with relative hypertension in sickle cell anemia. Am J Med. 1997 Feb; 102(2):171-7. PMID: 9217567

Charache S, Barton FB, Moore RD, Terrin ML, Steinberg MH, Dover GJ, Ballas SK, McMahon RP, Castro O, Orringer EP. Hydroxyurea and sickle cell anemia. Clinical utility of a myelosuppressive "switching" agent. The Multicenter Study of Hydroxyurea in Sickle Cell Anemia. Medicine (Baltimore). 1996 Nov; 75(6):300-26. PMID: 8982148

Figueirido MS, Steinberg MH. 5' hypersensitive site-2 and fetal hemoglobin in Brazilians. Hemoglobin. 1996 Nov; 20(4):435-8. PMID: 8936469

Steinberg MH. Review: sickle cell disease: present and future treatment. Am J Med Sci. 1996 Oct; 312(4):166-74. PMID: 8853065

Steinberg MH, Nagel RL, Lawrence C, Swaminathan V, Lu ZH, Plonczynski M, Harrell A. Beta-globin gene haplotype in Hb SC disease. Am J Hematol. 1996 Jul; 52(3):189-91. PMID: 8756085

Browne PV, Mosher DF, Steinberg MH, Hebbel RP. Disturbance of plasma and platelet thrombospondin levels in sickle cell disease. Am J Hematol. 1996 Apr; 51(4):296-301. PMID: 8602630

Lu ZH, Steinberg MH. Fetal hemoglobin in sickle cell anemia: relation to regulatory sequences cis to the beta-globin gene. Multicenter Study of Hydroxyurea. Blood. 1996 Feb 15; 87(4):1604-11. PMID: 8608254

Steinberg MH. Modulation of the phenotypic diversity of sickle cell anemia. Hemoglobin. 1996 Feb; 20(1):1-19. PMID: 8745428

Lee T, Esterhuyse T, Steinberg M, Schneider H. Demographic modelling of the HIV/AIDS epidemic on the Soweto population--results and health policy implications. S Afr Med J. 1996 Jan; 86(1):60-3. PMID: 8685784

Steinberg MH, Ballas SK, Brunson CY, Bookchin R. Sickle cell anemia in septuagenarians. Blood. 1995 Nov 15; 86(10):3997-8. PMID: 7579371

Ware RE, Steinberg MH, Kinney TR. Hydroxyurea: an alternative to transfusion therapy for stroke in sickle cell anemia. Am J Hematol. 1995 Oct; 50(2):140-3. PMID: 7572993

Steinberg MH. Transient disappearance of sickle hemoglobin after transfusion. Blood. 1995 Jun 15; 85(12):3766-7. PMID: 7780160

Steinberg MH. Genetic modulation of sickle cell anemia. Proc Soc Exp Biol Med. 1995 May; 209(1):1-13. PMID: 7724611

Steinberg MH, Hsu H, Nagel RL, Milner PF, Adams JG, Benjamin L, Fryd S, Gillette P, Gilman J, Josifovska O, et al. Gender and haplotype effects upon hematological manifestations of adult sickle cell anemia. Am J Hematol. 1995 Mar; 48(3):175-81. PMID: 7532353

Coleman MB, Lu ZH, Smith CM, Adams JG, Harrell A, Plonczynski M, Steinberg MH. Two missense mutations in the beta-globin gene can cause severe beta thalassemia. Hemoglobin Medicine Lake (beta 32[B14]leucine-->glutamine; 98 [FG5] valine-->methionine). J Clin Invest. 1995 Feb; 95(2):503-9. PMID: 7860732; PMCID: PMC295500

Coleman MB, Adams JG, Steinberg MH, Winter WP. A four base pair deletion 5' to the A gamma T gene is associated not only with decreased expression of the A gamma T-globin gene, but also of the G gamma-globin gene in cis. Am J Hematol. 1994 Dec; 47(4):307-11. PMID: 7526681

Steinberg MH. Sickle cell anemia and fetal hemoglobin. Am J Med Sci. 1994 Nov; 308(5):259-65. PMID: 7526687

Waye JS, Eng B, Coleman MB, Steinberg MH, Alter BP. Delta beta-thalassemia in an African-American: identification of the deletion endpoints and PCR-based diagnosis. Hemoglobin. 1994 Nov; 18(6):389-99. PMID: 7713743

Lu ZH, Steinberg MH. A new alpha alpha alpha anti-3.7 alpha-globin allele. Hemoglobin. 1994 Nov; 18(6):445-8. PMID: 7713750

Wethers DL, Ramirez GM, Koshy M, Steinberg MH, Phillips G, Siegel RS, Eckman JR, Prchal JT. Accelerated healing of chronic sickle-cell leg ulcers treated with RGD peptide matrix. RGD Study Group. Blood. 1994 Sep 15; 84(6):1775-9. PMID: 8080985

Platt OS, Brambilla DJ, Rosse WF, Milner PF, Castro O, Steinberg MH, Klug PP. Mortality in sickle cell disease. Life expectancy and risk factors for early death. N Engl J Med. 1994 Jun 9; 330(23):1639-44. PMID: 7993409

Embury SH, Hebbel RP, Mohandas N, Steinberg MH, eds. . Sickle Cell Disease: Basic Principles and Clinical Practice. Raven Press. New York. 1994; 902.

Merat A, Haghshenas M, Pour ZM, Plonczynski MW, Harrell AN, Coleman MB, Steinberg MH. Beta-thalassemia in southwestern Iran. Hemoglobin. 1993 Oct; 17(5):427-37. PMID: 8294202

Steinberg MH. DNA diagnosis for the detection of sickle hemoglobinopathies. Am J Hematol. 1993 Jun; 43(2):110-5. PMID: 8342537

Steinberg MH. Sickle cell trait vs disease. Hosp Pract (Off Ed). 1993 May 15; 28(5):21. PMID: 8338571

Steinberg MH. Case report: effects of iron deficiency and the -88 C-->T mutation on HbA2 levels in beta-thalassemia. Am J Med Sci. 1993 May; 305(5):312-3. PMID: 8484391

Coleman MB, Adams JG, Steinberg MH, Plonczynski MW, Harrell AH, Castro O, Winter WP. G gamma A gamma (beta+) hereditary persistence of fetal hemoglobin: the G gamma -158 C-->T mutation in cis to the -175 T-->C mutation of the A gamma-globin gene results in increased G gamma-globin synthesis. Am J Hematol. 1993 Feb; 42(2):186-90. PMID: 7679879

Coleman MB, Adams JG, Plonczynski MW, Harrell AH, Walker AM, Fairbanks V, Steinberg MH. Beta-thalassemia intermedia with exceptionally high hemoglobin A2: relationship to mutations in the beta-gene promoter. Am J Med Sci. 1992 Aug; 304(2):73-8. PMID: 1380206

West MS, Wethers D, Smith J, Steinberg M. Laboratory profile of sickle cell disease: a cross-sectional analysis. The Cooperative Study of Sickle Cell Disease. J Clin Epidemiol. 1992 Aug; 45(8):893-909. PMID: 1624972

Coleman MB, Steinberg MH, Harrell AH, Plonczynski MW, Walker AM, Adams JG. The -87 (C----A) beta(+)-thalassemia mutation in a black family. Hemoglobin. 1992; 16(5):399-401. PMID: 1428943

Gupta AK, Kirchner KA, Nicholson R, Adams JG, Schechter AN, Noguchi CT, Steinberg MH. Effects of alpha-thalassemia and sickle polymerization tendency on the urine-concentrating defect of individuals with sickle cell trait. J Clin Invest. 1991 Dec; 88(6):1963-8. PMID: 1752955; PMCID: PMC295777

Coleman MB, Steinberg MH, Adams JG. A four-base deletion 5' to the A gamma globin gene is a common polymorphism. Blood. 1991 Nov 1; 78(9):2473-4. PMID: 1681964

Steinberg MH, Adams JG. Hemoglobin A2: origin, evolution, and aftermath. Blood. 1991 Nov 1; 78(9):2165-77. PMID: 1932737

Steinberg MH. Prospects of gene therapy for hemoglobinopathies. Am J Med Sci. 1991 Nov; 302(5):298-303. PMID: 1750450

Steinberg MH, Coleman MB, Adams JG, Waye JS, Chui DH. High hemoglobin A2 beta-thalassemia. J Lab Clin Med. 1991 Oct; 118(4):382. PMID: 1940581

Waye JS, Chui DH, Eng B, Cai SP, Coleman MB, Adams JG, Steinberg MH. Hb S/beta zero-thalassemia due to the approximately 1.4-kb deletion is associated with a relatively mild phenotype. Am J Hematol. 1991 Oct; 38(2):108-12. PMID: 1719807

Adams JG, Hardy CL, Steinberg MH. Disappearance of the protein of a somatic mutation: a possible example of stem cell inactivation. Am J Physiol. 1991 Sep; 261(3 Pt 1):C448-54. PMID: 1887872

Steinberg MH. The interactions of alpha-thalassemia with hemoglobinopathies. Hematol Oncol Clin North Am. 1991 Jun; 5(3):453-73. PMID: 1864819

Steinberg MH. Erythropoietin for anemia of renal failure in sickle cell disease. N Engl J Med. 1991 May 9; 324(19):1369-70. PMID: 1759999

Tsevat J, Wong JB, Pauker SG, Steinberg MH. Neonatal screening for sickle cell disease: a cost-effectiveness analysis. J Pediatr. 1991 Apr; 118(4 Pt 1):546-54. PMID: 1901081

Coleman MB, Steinberg MH, Adams JG. Hemoglobin Terre Haute arginine beta 106. A posthumous correction to the original structure of hemoglobin Indianapolis. J Biol Chem. 1991 Mar 25; 266(9):5798-800. PMID: 2005117

Waye JS, Cai SP, Eng B, Clark C, Adams JG, Chui DH, Steinberg MH. High hemoglobin A2 beta 0-thalassemia due to a 532-basepair deletion of the 5' beta-globin gene region. Blood. 1991 Mar 1; 77(5):1100-3. PMID: 1995096

Rieder RF, Safaya S, Gillette P, Fryd S, Hsu H, Adams JG, Steinberg MH. Effect of beta-globin gene cluster haplotype on the hematological and clinical features of sickle cell anemia. Am J Hematol. 1991 Mar; 36(3):184-9. PMID: 1996558

Steinberg MH. Sickle cell anemia: pathophysiology, management, and prospects for the future. J Clin Apher. 1991; 6(4):221-3. PMID: 1816243

Weiss I, Cash FE, Coleman MB, Pressley A, Adams JG, Sanguansermsri T, Liebhaber SA, Steinberg MH. Molecular basis for alpha-thalassemia associated with the structural mutant hemoglobin Suan-Dok (alpha 2 109leu----arg) Blood. 1990 Dec 15; 76(12):2630-6. PMID: 2265255

Adams JG, Steinberg MH, Kazazian HH. Isolation and characterization of the translation product of a beta-globin gene nonsense mutation (beta 121 GAA----TAA). Br J Haematol. 1990 Aug; 75(4):561-7. PMID: 2207008

Steinberg MH. Sickle cell anaemia in a septuagenarian. Br J Haematol. 1989 Feb; 71(2):297-8. PMID: 2923816

Steinberg MH. Thalassemia: molecular pathology and management. Am J Med Sci. 1988 Nov; 296(5):308-21. PMID: 3057912

Kennedy AP, Williams B, Meydrech EF, Steinberg MH. Regional and temporal variation in oscillatory blood flow in sickle cell disease. Am J Hematol. 1988 Jun; 28(2):92-4. PMID: 2969189

Steinberg MH, West MS, Gallagher D, Mentzer W. Effects of glucose-6-phosphate dehydrogenase deficiency upon sickle cell anemia. Blood. 1988 Mar; 71(3):748-52. PMID: 3345344

Liebhaber SA, Coleman MB, Adams JG, Cash FE, Steinberg MH. Molecular basis for nondeletion alpha-thalassemia in American blacks. Alpha 2(116GAG----UAG). J Clin Invest. 1987 Jul; 80(1):154-9. PMID: 3597771; PMCID: PMC442213

Meyer LM, Adams JG, Steinberg MH, Miller IE, Stokes N. Screening for sickle cell trait: the Veterans Administration National Sickle Cell Program. Am J Hematol. 1987 Apr; 24(4):429-32. PMID: 3551591

Steinberg MH, Adams JG, Morrison WT, Pullen DJ, Abney R, Ibrahim A, Rieder RF. Hemoglobin Mississippi (beta 44ser----cys). Studies of the thalassemic phenotype in a mixed heterozygote with beta +-thalassemia. J Clin Invest. 1987 Mar; 79(3):826-32. PMID: 2434529; PMCID: PMC424211

Steinberg MH. Determinants of vaso-occlusive severity in sickle cell disease. Prog Clin Biol Res. 1987; 240:413-28. PMID: 3303060

Adams JG, Morrison WT, Barlow RL, Steinberg MH. Hb Mississippi [beta 44(CD3)Ser----Arg]: a new variant with anomalous properties. Hemoglobin. 1987; 11(5):435-52. PMID: 3429243

Steinberg MH, Embury SH. Alpha-thalassemia in blacks: interactions with the sickle hemoglobin gene. Birth Defects Orig Artic Ser. 1987; 23(5A):43-8. PMID: 3689929

Adams JG, Newman MV, Steinberg MH, DeSimone J. Effect of lead and ethanol upon gamma-globin synthesis in sickle reticulocytes. Am J Med Sci. 1986 Nov; 292(5):299-305. PMID: 2430453

Steinberg MH, Embury SH. Alpha-thalassemia in blacks: genetic and clinical aspects and interactions with the sickle hemoglobin gene. Blood. 1986 Nov; 68(5):985-90. PMID: 3533181

Steinberg MH, Gill F, Emanuel BS. Expression of two G-6-PD genes in an XX phenotypic male. Br J Haematol. 1986 Sep; 64(1):107-10. PMID: 3756097

Kennedy AP, Walsh DA, Nicholson R, Adams JG, Steinberg MH. Influence of HbS levels upon the hematological and clinical characteristics of sickle cell trait. Am J Hematol. 1986 May; 22(1):51-4. PMID: 3953566

Steinberg MH, Coleman MB, Adams JG, Hartmann RC, Saba H, Anagnou NP. A new gene deletion in the alpha-like globin gene cluster as the molecular basis for the rare alpha-thalassemia-1(--/alpha alpha) in blacks: HbH disease in sickle cell trait. Blood. 1986 Feb; 67(2):469-73. PMID: 3942832

Adams JG, Coleman MB, Hayes J, Morrison WT, Steinberg MH. Modulation of fetal hemoglobin synthesis by iron deficiency. N Engl J Med. 1985 Nov 28; 313(22):1402-5. PMID: 2414661

Steinberg MH. Sickle cell trait and splenic syndrome. JAMA. 1985 Oct 11; 254(14):1901-2. PMID: 4046113

Steinberg MH. Role of hemoglobin instability in premature red cell destruction. Prog Clin Biol Res. 1985; 195:149-57. PMID: 4059266

Steinberg MH, Coleman MB, Adams JG, Rosenstock W. Interaction between HBS-beta-o-thalassemia and alpha-thalassemia. Am J Med Sci. 1984 Dec; 288(5):195-9. PMID: 6083725

Steinberg MH. Review: the sickle hemoglobinopathies--genetic analyses of common phenocopies and new molecular approaches to treatment. Am J Med Sci. 1984 Nov; 288(4):169-74. PMID: 6208780

Dreiling BJ, Steinberg MH. Neglected iron deficiency. J Miss State Med Assoc. 1984 Sep; 25(9):231-3. PMID: 6492150

Steinberg MH, Rosenstock W, Coleman MB, Adams JG, Platica O, Cedeno M, Rieder RF, Wilson JT, Milner P, West S. Effects of thalassemia and microcytosis on the hematologic and vasoocclusive severity of sickle cell anemia. Blood. 1984 Jun; 63(6):1353-60. PMID: 6722353

Balducci L, Hardy C, Dreiling B, Tavassoli M, Steinberg MH. Pure red blood cell aplasia associated with paraproteinemia: in vitro studies of erythropoiesis. Haematologia (Budap). 1984; 17(3):353-7. PMID: 6442912

Balducci L, Little DD, Khansur T, Steinberg MH. Carcinomatous meningitis in small cell lung cancer. Am J Med Sci. 1984 Jan-Feb; 287(1):31-3. PMID: 6322586

Steinberg MH, Adams JG. Thalassemic hemoglobinopathies. Am J Pathol. 1983 Dec; 113(3):396-409. PMID: 6359893; PMCID: PMC1916350

Steinberg MH, Coleman MB, Adams JG, Platica O, Gillette P, Rieder RF. The effects of alpha-thalassaemia in HbSC disease. Br J Haematol. 1983 Nov; 55(3):487-92. PMID: 6639890

Steinberg MH, Gatling RR, Tavassoli M. Evidence of hyposplenism in the presence of splenomegaly. Scand J Haematol. 1983 Nov; 31(5):437-9. PMID: 6685914

Steinberg MH, Hebbel RP. Clinical diversity of sickle cell anemia: genetic and cellular modulation of disease severity. Am J Hematol. 1983 Jun; 14(4):405-16. PMID: 6190397

Balducci L, Little DD, Glover NG, Hardy CS, Steinberg MH. Granulocyte reserve in cancer and malnutrition. Ann Intern Med. 1983 May; 98(5 Pt 1):610-1. PMID: 6405668

Teetson W, Cartwright C, Dreiling BJ, Steinberg MH. The leukocyte composition of peripheral blood buffy coat. Am J Clin Pathol. 1983 Apr; 79(4):500-1. PMID: 6837515

Smith CM, Hedlund B, Cich JA, Tukey DP, Olson M, Steinberg MH, Adams JG. Hemoglobin North Shore: a variant hemoglobin associated with the phenotype of beta-thalassemia. Blood. 1983 Feb; 61(2):378-83. PMID: 6821704

Steinberg MH, Dreiling BJ. Microcytosis. Its significance and evaluation. JAMA. 1983 Jan 7; 249(1):85-7. PMID: 6848788

Steinberg MH, Adams JG. beta-thalassemia-? Selected pseudogenes. Med Hypotheses. 1982 Dec; 9(6):599-604. PMID: 6820119

Hebbel RP, Eaton JW, Balasingam M, Steinberg MH. Spontaneous oxygen radical generation by sickle erythrocytes. J Clin Invest. 1982 Dec; 70(6):1253-9. PMID: 6294138; PMCID: PMC370342

Steinberg MH. Sickle cell anemia and iron deficiency. JAMA. 1982 Nov 5; 248(17):2112-3. PMID: 7120637

Steinberg MH, Adams JG, Hendrix R. Sickle cell-beta-thalassemia: a common phenocopy of sickle cell anemia. J Miss State Med Assoc. 1982 Nov; 23(11):319-21. PMID: 7175930

Adams JG, Morrison WT, Steinberg MH. Hemoglobin Parchman: double crossover within a single human gene. Science. 1982 Oct 15; 218(4569):291-3. PMID: 7123235

Steinberg MH, Coleman MB, Adams JG. Beta-thalassemia with exceptionally high hemoglobin A2. Differential expression of the delta-globin gene in the presence of beta-thalassemia. J Lab Clin Med. 1982 Oct; 100(4):548-57. PMID: 6288819

Steinberg MH, Adams JG. Thalassemia: recent insights into molecular mechanisms. Am J Hematol. 1982 Feb; 12(1):81-92. PMID: 6278929

Hebbel RP, Eaton JW, Steinberg MH, White JG. Erythrocyte/endothelial interactions in the pathogenesis of sickle-cell disease: a "real logical" assessment. Blood Cells. 1982; 8(1):163-73. PMID: 7115974

Hebbel RP, Moldow CF, Steinberg MH. Modulation of erythrocyte-endothelial interactions and the vasocclusive severity of sickling disorders. Blood. 1981 Nov; 58(5):947-52. PMID: 7296004

Hebbel RP, Steinberg MH, Eaton JW. Erythrocyte calcium abnormalities in sickle cell disease. Prog Clin Biol Res. 1981; 51:321-32. PMID: 7022473

Adams JG, Steinberg MH, Newman MV, Morrison WT, Benz EJ, Iyer R. beta-Thalassemia present in cis to a new beta-chain structural variant, Hb Vicksburg [beta 75 (E19)Leu leads to 0]. Proc Natl Acad Sci U S A. 1981 Jan; 78(1):469-73. PMID: 6165992; PMCID: PMC319075

Steinberg MH, Coleman MB, Garver FA, Grenett HE, Pressley A, Adams JG. Effects of dexamethasone on fetal hemoglobin synthesis in peripheral blood erythroid burst-forming units. Am J Hematol. 1981; 10(1):37-45. PMID: 6167163

Adams JG, Steinberg MH. Low output hemoglobins which produce the phenotype of thalassemia. Prog Clin Biol Res. 1981; 55:81-98. PMID: 6895257

Steinberg MH, Coleman MB, Pressley A, Adams JG. Globin biosynthesis in erythroid bursts of heterozygous alpha or beta thalassaemia. Br J Haematol. 1981 Jan; 47(1):57-65. PMID: 7437346

Hebbel RP, Eaton JW, Steinberg MH, White JG. Erythrocyte/endothelial interactions and the vasocclusive severity of sickle cell disease. Prog Clin Biol Res. 1981; 55:145-62. PMID: 7291188

Balducci L, Steinberg MH. Prolonged remission of metastatic rhabdomyosarcoma: The use of chemotherapy and nutritional support. J Miss State Med Assoc. 1980 Sep; 21(9):181-3. PMID: 6777498

Hebbel RP, Boogaerts MA, Eaton JW, Steinberg MH. Erythrocyte adherence to endothelium in sickle-cell anemia. A possible determinant of disease severity. N Engl J Med. 1980 May 1; 302(18):992-5. PMID: 7366623

Hebbel RP, Boogaerts MA, Koresawa S, Jacob HS, Eaton JW, Steinberg MH. Erytrocyte adherence to endothelium as a determinant of vasocclusive severity in sickle cell disease. Trans Assoc Am Physicians. 1980; 93:94-9. PMID: 7245585

Balducci L, Dreiling B, Steinberg MH, Kakaiya RM, Morrison FS. Multifocal eosinophilic granuloma: description of an unusual case. South Med J. 1979 Jul; 72(7):884-5. PMID: 451705

Adams JG, Steinberg MH, Boxer LA, Baehner RL, Forget BG, Tsistrakis GA. The structure of hemoglobin Indianapolis [beta112(G14) arginine]. An unstable variant detectable only by isotopic labeling. J Biol Chem. 1979 May 10; 254(9):3479-82. PMID: 429365

Adams JG, Boxer LA, Baehner RL, Forget BG, Tsistrakis GA, Steinberg MH. Hemoglobin Indianapolis (beta 112[G14] arginine). An unstable beta-chain variant producing the phenotype of severe beta-thalassemia. J Clin Invest. 1979 May; 63(5):931-8. PMID: 447835; PMCID: PMC372034

Coleman MB, Steinberg MH, Oelshlegel FJ, Larson AD, Hart LT. Isolation of Plasmodium berghei by hemolysin lysis of infected erythrocytes and evidence for a parasite hexokinase. J Parasitol. 1979 Apr; 65(2):222-5. PMID: 376819

Steinberg MH, Coleman MF, Pennebaker JB. Diamond-Blackfan syndrome: evidence for T-cell mediated suppression of erythroid development and a serum blocking factor associated with remission. Br J Haematol. 1979 Jan; 41(1):57-68. PMID: 311222

Steinberg MH, Eaton JW, Berger E, Coleman MB, Oelshlegel FJ. Erythrocyte calcium abnormalities and the clinical severity of sickling disorders. Br J Haematol. 1978 Dec; 40(4):533-39. PMID: 728370

Steinberg MH, Adams JG. Laboratory Diagnosis of sickling hemoglobinopathies. South Med J. 1978 Apr; 71(4):413-6. PMID: 635620

Newcomb MM, Balducci L, Coleman MB, Steinberg MH. Erythroleukemia: in vitro studies of erythropoiesis. Am J Hematol. 1978; 5(4):291-5. PMID: 288310

Steinberg MH, Adams JG. Hemoglobin F levels do not change during the painful crisis of sickle cell anemia. Am J Obstet Gynecol. 1977 Nov 15; 129(6):712-3. PMID: 920775

Udomratn T, Steinberg MH, Campbell GD, Oelshlegel FJ. Effects of ascorbic acid on glucose-6-phosphate dehydrogenase-deficient erythrocytes: studies in an animal model. Blood. 1977 Mar; 49(3):471-5. PMID: 836955

Adams JG, Steinberg MH. Alpha-thalassemia. Am J Hematol. 1977; 2(3):317-25. PMID: 596373

Steinberg MH, Dreiling BJ, Lovell WJ. Sickle cell anemia: erythrokinetics, blood volumes, and a study of possible determinants of severity. Am J Hematol. 1977; 2(1):17-23. PMID: 868865

Steinberg MH, Coleman M, Dreiling B. Unbalanced globin chain synthesis in erythroid precursor cells of heterozygous alpha-thalassaemia. Br J Haematol. 1976 Sep; 34(1):55-60. PMID: 952769

Steinberg MH, Lovell WJ, Wells S, Coleman M, Dreiling BJ, Adams JG. Hemoglobin Hope: studies of oxygen equilibrium in heterozygotes, hemoglobin S-Hope disease, and isolated hemoglobin Hope. J Lab Clin Med. 1976 Jul; 88(1):125-31. PMID: 932531

Udomratn T, Steinberg MH, Dreiling BJ, Lockhard V. Circulating micromegakaryocytes signaling blast transformation of chronic myeloid leukaemia. Scand J Haematol. 1976 May; 16(5):394-400. PMID: 1065956

Steinberg MH, Dreiling BJ. Clinical, hematologic and biosynthetic studies in sickle cell-betao-thalassemia: a comparison with sickle cell anemia. Am J Hematol. 1976; 1(1):35-44. PMID: 984035

Steinberg MH. Haemoglobin C/alpha thalassaemia: haematological and biosynthetic studies. Br J Haematol. 1975 Jul; 30(3):337-42. PMID: 1201216

Campbell GD, Steinberg MH, Bower JD. Letter: Ascorbic acid-induced hemolysis in G-6-PD deficiency. Ann Intern Med. 1975 Jun; 82(6):810. PMID: 1138591

Steinberg MH, Adams JG, Dreiling BJ. Alpha thalassaemia in adults with sickle-cell trait. Br J Haematol. 1975 May; 30(1):31-7. PMID: 1191571

Steinberg MH, Adams JG, Thigpen JT, Morrison FS, Dreiling BJ. Hemoglobin Hope (alpha 2 beta 2(136-gly-asp))-S disease: clinical and biochemical studies. J Lab Clin Med. 1974 Nov; 84(5):632-42. PMID: 4283785

Steinberg MH. Letter: Leukocyte alkaline phosphatase. Ann Intern Med. 1974 Aug; 81(2):274. PMID: 4843592

Steinberg MH, Dreiling BJ. Glucose-6-phosphate dehydrogenase deficiency in Sickle-cell anemia. A study in adults. Ann Intern Med. 1974 Feb; 80(2):217-20. PMID: 4811795

Thigpen JT, Steinberg MH, Beutler E, Gillespie GT, Dreiling BJ, Morrison FS. Glucose-6-phosphate dehydrogenase Jackson. A new variant associated with hemolytic anemia. Acta Haematol. 1974; 51(5):310-4. PMID: 4209318

Steinberg MH, Breiling BJ. Vascular lesions in hemophilia B. N Engl J Med. 1973 Sep 13; 289(11):592. PMID: 4723113

Willard RF, Lovell WJ, Dreiling BJ, Steinberg MH. Electrophoresis of hemoglobin on polyacrylamide gels: precise method for measurement of hemoglobin A2. Clin Chem. 1973 Sep; 19(9):1082-4. PMID: 4744815

Steinberg MH, Dreiling BJ. Chronic granulocytic leukemia. Prolonged survival, muscle infiltration and sea-blue histiocytosis. Am J Med. 1973 Jul; 55(1):93-8. PMID: 4123736

Steinberg MH, Dreiling BJ, Morrison FS, Necheles TF. Mild sickle cell disease. Clinical and laboratory studies. JAMA. 1973 Apr 16; 224(3):317-21. PMID: 4739533

Steinberg MH, Dreiling BJ, Robinson F, Hallford C. The ultrastructure of developing bone marrow implants: a scanning electron microscope study. Acta Anat (Basel). 1973; 84(1):1-9. PMID: 4265082

Morrison FS, Tatum WT, Dreiling BJ, Steinberg MH. Hodgkin's disease--a curable malignancy. J Miss State Med Assoc. 1972 Feb; 13(2):45-7. PMID: 5059229

Steinberg MH, Charm SE. Effect of high concentrations of leukocytes on whole blood viscosity. Blood. 1971 Sep; 38(3):299-301. PMID: 5289281

Steinberg MH, Necheles TF. Erythrocyte glutathione peroxidase deficiency. Biochemical studies on the mechanisms of drug-induced hemolysis. Am J Med. 1971 Apr; 50(4):542-6. PMID: 5572598

Necheles TF, Steinberg MH, Cameron D. Erythrocyte glutathione-peroxidase deficiency. Br J Haematol. 1970 Nov; 19(5):605-12. PMID: 5481505

Steinberg MH, Geary CG, Crosby WH. Acute granulocytic leukemia complicating Hodgkin's disease. Arch Intern Med. 1970 Mar; 125(3):496-8. PMID: 5264513

Steinberg M, Brauer MJ, Necheles TF. Acute hemolytic anemia associated with erythrocyte glutathione-peroxidase deficiency. Arch Intern Med. 1970 Feb; 125(2):302-3. PMID: 5412019

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 331 publications over 45 distinct years, with a maximum of 15 publications in 2011

Bar chart showing 331 publications over 45 distinct years, with a maximum of 15 publications in 2011

Year	Publications
1980	3
1981	7
1982	8
1983	8
1984	6
1985	3
1986	5
1987	6
1988	3
1989	1
1990	2
1991	14
1992	3
1993	5
1994	7
1995	6
1996	8
1997	7
1998	3
1999	7
2000	5
2001	9
2002	2
2003	6
2004	7
2005	10
2006	12
2007	9
2008	13
2009	12
2010	8
2011	15
2012	13
2013	12
2014	13
2015	11
2016	9
2017	14
2018	6
2019	6
2020	7
2021	4
2022	10
2023	3
2024	3

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fetal hemoglobin
genomics
sickle cell
SNPs

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