Marc Lenburg, PhD
Professor
Boston University School of Medicine
Dept of Medicine
Computational Biomedicine Section

PhD, University of California, San Francisco



Expertise in computational approaches to leverage genome-wide datasets (especially genome-wide gene-expression) for clinical and biological insight. Interests include developing and applying these tools for translational research.

Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Division of Graduate Medical Sciences


Professor
Boston University School of Medicine
Department of Pathology & Laboratory Medicine


Member
Boston University
Department of Bioinformatics Graduate Program




Molecular and Imaging biomarkers for early lung cancer detection in the setting of Indeterminate Pulmonary Nodu
09/23/2016 - 08/31/2017 (PI)
NIH/National Cancer Institute
1R01CA210360-01

The Boston University-UCLA Lung Cancer Biomarker Development Lab
09/20/2016 - 08/31/2017 (Co-PI)
PI: Avrum Spira, MD
NIH/National Cancer Institute
1U01CA214182-01

Integrative Omics to Discover Molecular Determinants of COPD
06/01/2016 - 05/31/2017 (PI)
NIH/National Heart, Lung, and Blood Institute
4R01HL118542-04

Molecular biomarkers of airway and lung linking COPD and Lung Cancer
09/15/2011 - 07/31/2016 (SP Co-PI of Sub-Project / SP)
NIH/National Cancer Institute
5R01CA164783-04

Integrative Omics to Discover Molecular Determinants of COPD
08/15/2013 - 05/31/2016 (PI)
NIH/National Heart, Lung, and Blood Institute
5R01HL118542-03

Validation of a Genomic Biomarker of Responses to Environmental Tobacco Smoke
08/08/2011 - 06/30/2015 (PI)
NIH/National Institute of Environmental Health Sciences
5R01ES020425-02




Yr Title Project-Sub Proj Pubs
2016 Molecular and Imaging Biomarkers for Early Lung Cancer Detection in the Setting of Indeterminate Pulmonary Nodules 1R01CA210360-01
2016 The Boston University-UCLA Lung Cancer Biomarker Development Lab 1U01CA214182-01
2016 Integrative Omics to Discover Molecular Determinants of COPD 4R01HL118542-04 1
2015 The UCLA - Boston University Lung Cancer Biomarker Development Laboratory 3U01CA152751-05S2 12
2014 Integrative Omics to Discover Molecular Determinants of COPD 5R01HL118542-02 1
2014 Molecular biomarkers of airway and lung linking COPD and Lung Cancer 5R01CA164783-04 10
2014 The UCLA - Boston University Lung Cancer Biomarker Development Laboratory 5U01CA152751-05 12
2013 Integrative Omics to Discover Molecular Determinants of COPD 1R01HL118542-01 1
2013 Molecular biomarkers of airway and lung linking COPD and Lung Cancer 5R01CA164783-03 10
2013 Molecular biomarkers of airway and lung linking COPD and lung cancer 3R01CA164783-03S1 10
Showing 10 of 24 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Shared Gene Expression Alterations in Nasal and Bronchial Epithelium for Lung Cancer Detection. J Natl Cancer Inst. 2017 Jul 01; 109(7). PMID: 28376173; DOI: 10.1093/jnci/djw327;.
  2. Hu Z, Mao JH, Curtis C, Huang G, Gu S, Heiser L, Lenburg ME, Korkola JE, Bayani N, Samarajiwa S, Seoane JA, Dane MA, Esch A, Feiler HS, Wang NJ, Hardwicke MA, Laquerre S, Jackson J, Wood KW, Weber B, Spellman PT, Aparicio S, Wooster R, Caldas C, Gray JW. Erratum to: Genome co-amplification upregulates a mitotic gene network activity that predicts outcome and response to mitotic protein inhibitors in breast cancer. Breast Cancer Res. 2017 Feb 09; 19(1):17. PMID: 28183333; DOI: 10.1186/s13058-017-0809-6;.
  3. Vasilescu DM, Phillion AB, Tanabe N, Kinose D, Paige DF, Kantrowitz JJ, Liu G, Liu H, Fishbane N, Verleden SE, Vanaudenaerde BM, Lenburg M, Stevenson CS, Spira A, Cooper JD, Hackett TL, Hogg JC. Nondestructive cryomicro-CT imaging enables structural and molecular analysis of human lung tissue. J Appl Physiol (1985). 2017 Jan 01; 122(1):161-169.View Related Profiles. PMID: 27856720; DOI: 10.1152/japplphysiol.00838.2016;.
  4. Kusko RL, Brothers JF, Tedrow J, Pandit K, Huleihel L, Perdomo C, Liu G, Juan-Guardela B, Kass D, Zhang S, Lenburg M, Martinez F, Quackenbush J, Sciurba F, Limper A, Geraci M, Yang I, Schwartz DA, Beane J, Spira A, Kaminski N. Integrated Genomics Reveals Convergent Transcriptomic Networks Underlying Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2016 Oct 15; 194(8):948-960.View Related Profiles. PMID: 27104832.
  5. Moses E, Wang T, Corbett S, Jackson GR, Drizik E, Perdomo C, Perdomo C, Kleerup E, Brooks D, O''Connor G, Dubinett S, Hayden P, Lenburg ME, Spira A. Molecular Impact of Electronic Cigarette Aerosol Exposure in Human Bronchial Epithelium. Toxicol Sci. 2017 Jan; 155(1):248-257.View Related Profiles. PMID: 27701119; DOI: 10.1093/toxsci/kfw198;.
  6. Lam S, Mandrekar SJ, Gesthalter Y, Allen Ziegler KL, Seisler DK, Midthun DE, Mao JT, Aubry MC, McWilliams A, Sin DD, Shaipanich T, Liu G, Johnson E, Bild A, Lenburg ME, Ionescu DN, Mayo J, Yi JE, Tazelaar H, Harmsen WS, Smith J, Spira AE, Beane J, Limburg PJ, Szabo E. A Randomized Phase IIb Trial of myo-Inositol in Smokers with Bronchial Dysplasia. Cancer Prev Res (Phila). 2016 Dec; 9(12):906-914.View Related Profiles. PMID: 27658890.
  7. Hu Z, Mao JH, Curtis C, Huang G, Gu S, Heiser L, Lenburg ME, Korkola JE, Bayani N, Samarajiwa S, Seoane JA, A Dane M, Esch A, Feiler HS, Wang NJ, Hardwicke MA, Laquerre S, Jackson J, W Wood K, Weber B, Spellman PT, Aparicio S, Wooster R, Caldas C, Gray JW. Genome co-amplification upregulates a mitotic gene network activity that predicts outcome and response to mitotic protein inhibitors in breast cancer. Breast Cancer Res. 2016 Jul 01; 18(1):70. PMID: 27368372; PMCID: PMC4930593; DOI: 10.1186/s13058-016-0728-y;.
  8. Vachani A, Whitney DH, Parsons EC, Lenburg M, Ferguson JS, Silvestri GA, Spira A. Clinical Utility of a Bronchial Genomic Classifier in Patients With Suspected Lung Cancer. Chest. 2016 Jul; 150(1):210-8.View Related Profiles. PMID: 26896702; DOI: 10.1016/j.chest.2016.02.636;.
  9. Wang TW, Vermeulen RC, Hu W, Liu G, Xiao X, Alekseyev Y, Xu J, Reiss B, Steiling K, Downward GS, Silverman DT, Wei F, Wu G, Li J, Lenburg ME, Rothman N, Spira A, Lan Q. Gene-expression profiling of buccal epithelium among non-smoking women exposed to household air pollution from smoky coal. Carcinogenesis. 2015 Dec; 36(12):1494-501.View Related Profiles. PMID: 26468118; PMCID: PMC4675833; DOI: 10.1093/carcin/bgv150;.
  10. Sze MA, Dimitriu PA, Suzuki M, McDonough JE, Campbell JD, Brothers JF, Erb-Downward JR, Huffnagle GB, Hayashi S, Elliott WM, Cooper J, Sin DD, Lenburg ME, Spira A, Mohn WW, Hogg JC. Host Response to the Lung Microbiome in Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2015 Aug 15; 192(4):438-45.View Related Profiles. PMID: 25945594; PMCID: PMC4595667; DOI: 10.1164/rccm.201502-0223OC;.
Showing 10 of 78 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 78 publications over 20 distinct years, with a maximum of 9 publications in 2010

YearPublications
19921
19931
19942
19961
20011
20031
20041
20053
20063
20075
20086
20098
20109
20115
20125
20136
20146
20156
20166
20172
Contact for Mentoring:


75 E. Newton St Evans Building
Boston MA 02118
Google Map


Lenburg's Networks
Click the "See All" links for more information and interactive visualizations
Concepts
_
Co-Authors
_
Similar People
_
Same Department