Katrina Steiling, MD
Assistant Professor
Boston University School of Medicine
Dept of Medicine
Computational Biomedicine Section

MD, Boston University School of Medicine
MSc, Boston University



Dr. Steiling is an Assistant Professor of Medicine. She sees patients in the multidisciplinary Thoracic Oncology Clinic and attends in the Medical Intensive Care Unit at Boston Medical Center.

Dr. Steiling’s research focuses on applying high-throughput genomic tools and emerging computational methods to develop improved diagnostics, prognostics, and risk stratification tools for phenotypically complex lung diseases such as chronic obstructive pulmonary disease (COPD) and lung cancer. Dr. Steiling’s primary research involves gene expression profiling of the airway epithelium from individuals with COPD in order to understand the molecular mechanisms of this disease and its relationship to lung cancer. She has also worked to apply airway gene expression profiling to the diagnosis of lung cancer, to understand the relationship between smoking-induced changes in gene expression in the bronchial airway and the upper airway, and to elucidate the relationship between smoking-induced changes in airway gene and protein expression.

Research interests include:
-Airway gene expression
-Bioinformatics
-Chronic Obstructive Pulmonary Disease (COPD)
-Lung Cancer

Clinical interests include:
-Thoracic Oncology
-Pulmonary Medicine
-Critical Care Medicine

Member
Boston University
Department of Bioinformatics Graduate Program




Nasal Transcriptomic Biomarkers for the Diagnostic Evaluation of Lung Nodules Found by LDCT Screening
08/01/2014 - 07/31/2018 (PI)
Lahey Clinic, Inc. Am Thorac./LUNGevity

Characterizing Molecular Subphenotypes of chronic obstructive Pulmonary Disease
09/15/2015 - 09/15/2016 (PI)
The CHEST Foundation

Nasal Biomarker for the Early Detection of Lung Cancer in Patients with COPD
03/01/2014 - 09/30/2015 (PI)
Center for Integration of Medicine and Innovative Technology

Boston University Clinical and Translational Science Award (CTSA) Program KL2
05/01/2012 - 04/30/2014 (SP Co-PI of Sub-Project / SP)
PI: David M. Center, MD
NIH/National Center for Health Research Resources
3KL2TR000158-05S1

Airway Genomic Biomarkers for the Early Detection of Lung Cancer
07/01/2011 - 06/30/2013 (PI)
American Association for Cancer Research

Airway Genomic Biomarkers for the Early Detection of Lung Cancer
07/01/2011 - 06/30/2012 (PI)
AACR (American Association for Cancer Research )




Yr Title Project-Sub Proj Pubs
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Christenson SA, Steiling K. Shifting from Correlation to Causation: Challenges for the Future of Unbiased Molecular Studies in Inflammatory Lung Disease. Am J Respir Crit Care Med. 2017 Jan 01; 195(1):5-7. PMID: 28035851; DOI: 10.1164/rccm.201608-1751ED;.
  2. Bhatt N, Sloan JM, O'Hara CJ, Oommen R, Steiling K, Litle VR. Extranodal Marginal Zone Endobronchial Lymphoma Associated With Hepatitis C. Ann Thorac Surg. 2016 Nov; 102(5):e407-e408.View Related Profiles. PMID: 27772593; DOI: 10.1016/j.athoracsur.2016.04.060;.
  3. Wang TW, Vermeulen RC, Hu W, Liu G, Xiao X, Alekseyev Y, Xu J, Reiss B, Steiling K, Downward GS, Silverman DT, Wei F, Wu G, Li J, Lenburg ME, Rothman N, Spira A, Lan Q. Gene-expression profiling of buccal epithelium among non-smoking women exposed to household air pollution from smoky coal. Carcinogenesis. 2015 Dec; 36(12):1494-501.View Related Profiles. PMID: 26468118; PMCID: PMC4675833; DOI: 10.1093/carcin/bgv150;.
  4. Steiling K, Christenson SA. Targeting ''types: Precision Medicine in Pulmonary Disease. Am J Respir Crit Care Med. 2015 May 15; 191(10):1093-4. PMID: 25978565; DOI: 10.1164/rccm.201503-0613ED;.
  5. Grayson PC, Steiling K, Platt M, Berman JS, Zhang X, Xiao J, Alekseyev YO, Liu G, Monach PA, Kaplan MJ, Spira A, Merkel PA. Defining the nasal transcriptome in granulomatosis with polyangiitis (Wegener''s). Arthritis Rheumatol. 2015 May; 67(8):2233-9.View Related Profiles. PMID: 25939343; PMCID: PMC4519398; DOI: 10.1002/art.39185;.
  6. Christenson SA, Steiling K, van den Berge M, Hijazi K, Hiemstra PS, Postma DS, Lenburg ME, Spira A, Woodruff PG. Asthma-COPD overlap. Clinical relevance of genomic signatures of type 2 inflammation in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2015 Apr 1; 191(7):758-66.View Related Profiles. PMID: 25611785; PMCID: PMC4407484; DOI: 10.1164/rccm.201408-1458OC;.
  7. Gesthalter YB, Vick J, Steiling K, Spira A. Translating the transcriptome into tools for the early detection and prevention of lung cancer. Thorax. 2015 May; 70(5):476-81.View Related Profiles. PMID: 25628310; DOI: 10.1136/thoraxjnl-2014-206605;.
  8. Stevenson EK, Sloan KA, Narsule CK, Kretschman DM, Sarita-Reyes CD, Steiling K, Ebright MI. Catamenial hemothorax in a patient with multiple sclerosis. Am J Respir Crit Care Med. 2014 Dec 15; 190(12):e69-70.View Related Profiles. PMID: 25496111; DOI: 10.1164/rccm.201407-1283IM;.
  9. Lamontagne M, Timens W, Hao K, Bossé Y, Laviolette M, Steiling K, Campbell JD, Couture C, Conti M, Sherwood K, Hogg JC, Brandsma CA, van den Berge M, Sandford A, Lam S, Lenburg ME, Spira A, Paré PD, Nickle D, Sin DD, Postma DS. Genetic regulation of gene expression in the lung identifies CST3 and CD22 as potential causal genes for airflow obstruction. Thorax. 2014 Nov; 69(11):997-1004.View Related Profiles. PMID: 25182044; DOI: 10.1136/thoraxjnl-2014-205630;.
  10. Kathuria H, Gesthalter Y, Spira A, Brody JS, Steiling K. Updates and controversies in the rapidly evolving field of lung cancer screening, early detection, and chemoprevention. Cancers (Basel). 2014; 6(2):1157-79.View Related Profiles. PMID: 24840047; DOI: 10.3390/cancers6021157;.
Showing 10 of 22 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 22 publications over 9 distinct years, with a maximum of 5 publications in 2015

YearPublications
20071
20083
20092
20112
20133
20144
20155
20161
20171
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Computational Biology
Gene Expression Profiling
Gene Expresssion
Genomics
Lung Neoplasms
Pulmonary Disease, Chronic Obstructive

Available to Mentor as: (Review Mentor Role Definitions):
  • Co-Mentor or Peer Mentor
  • Project Mentor
  • Research / Scholarly Mentor
Contact for Mentoring:
  • Email (see 'Contact Info')


75 E. Newton St Evans Building
Boston MA 02118
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