Frank Schembri, MD
Assistant Professor
Boston University School of Medicine
Dept of Medicine
Pulmonary, Allergy, Sleep & Critical Care Medicine Section

MD, University of Medicine and Dentistry of New Jersey



Expertise in collecting, processing and storage of clinical specimens from the upper and lower airways of patients.

Active Staff Privileges
Boston Medical Center
Department of Medicine




IMPACT OF SYMBICORT IN AIRWAY EPITHELIAL GENE EXPRESSION
12/01/2010 - 09/30/2014 (PI)
AstraZeneca

Impact of Symbicort on Airway Epithelial Gene Expression
12/01/2010 - 06/30/2012 (PI)
AstraZeneca

Microarray Cell Line Standardization
08/15/2008 - 08/14/2009 (PI)
Allegro Diagnostics




Yr Title Project-Sub Proj Pubs
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Perdomo C, Campbell JD, Gerrein J, Tellez CS, Garrison CB, Walser TC, Drizik E, Si H, Gower AC, Vick J, Anderlind C, Jackson GR, Mankus C, Schembri F, O''Hara C, Gomperts BN, Dubinett SM, Hayden P, Belinsky SA, Lenburg ME, Spira A. MicroRNA 4423 is a primate-specific regulator of airway epithelial cell differentiation and lung carcinogenesis. Proc Natl Acad Sci U S A. 2013 Nov 19; 110(47):18946-51.View Related Profiles. PMID: 24158479; PMCID: PMC3839685; DOI: 10.1073/pnas.1220319110;.
  2. Stevenson E, Schembri F, Green DM, Burns JD. Serotonin syndrome associated with clozapine withdrawal. JAMA Neurol. 2013 Aug; 70(8):1054-5.View Related Profiles. PMID: 23753931; DOI: 10.1001/jamaneurol.2013.95;.
  3. Beane J, Vick J, Schembri F, Anderlind C, Gower A, Campbell J, Luo L, Zhang XH, Xiao J, Alekseyev YO, Wang S, Levy S, Massion PP, Lenburg M, Spira A. Characterizing the impact of smoking and lung cancer on the airway transcriptome using RNA-Seq. Cancer Prev Res (Phila). 2011 Jun; 4(6):803-17.View Related Profiles. PMID: 21636547; PMCID: PMC3694393; DOI: 10.1158/1940-6207.CAPR-11-0212;.
  4. Perdomo C, Spira A, Schembri F. MiRNAs as regulators of the response to inhaled environmental toxins and airway carcinogenesis. Mutat Res. 2011 Dec 1; 717(1-2):32-7.View Related Profiles. PMID: 21549133; DOI: 10.1016/j.mrfmmm.2011.04.005;.
  5. Zhang X, Sebastiani P, Liu G, Schembri F, Zhang X, Dumas YM, Langer EM, Alekseyev Y, O'Connor GT, Brooks DR, Lenburg ME, Spira A. Similarities and differences between smoking-related gene expression in nasal and bronchial epithelium. Physiol Genomics. 2010 Mar 3; 41(1):1-8.View Related Profiles. PMID: 19952278; PMCID: PMC2841495; DOI: 10.1152/physiolgenomics.00167.2009;.
  6. Schembri F, Sridhar S, Perdomo C, Gustafson AM, Zhang X, Ergun A, Lu J, Liu G, Zhang X, Bowers J, Vaziri C, Ott K, Sensinger K, Collins JJ, Brody JS, Getts R, Lenburg ME, Spira A. MicroRNAs as modulators of smoking-induced gene expression changes in human airway epithelium. Proc Natl Acad Sci U S A. 2009 Feb 17; 106(7):2319-24.View Related Profiles. PMID: 19168627; PMCID: PMC2650144; DOI: 10.1073/pnas.0806383106;.
  7. Sridhar S, Schembri F, Zeskind J, Shah V, Gustafson AM, Steiling K, Liu G, Dumas YM, Zhang X, Brody JS, Lenburg ME, Spira A. Smoking-induced gene expression changes in the bronchial airway are reflected in nasal and buccal epithelium. BMC Genomics. 2008; 9:259.View Related Profiles. PMID: 18513428; PMCID: PMC2435556; DOI: 10.1186/1471-2164-9-259;.
  8. Spira A, Beane JE, Shah V, Steiling K, Liu G, Schembri F, Gilman S, Dumas YM, Calner P, Sebastiani P, Sridhar S, Beamis J, Lamb C, Anderson T, Gerry N, Keane J, Lenburg ME, Brody JS. Airway epithelial gene expression in the diagnostic evaluation of smokers with suspect lung cancer. Nat Med. 2007 Mar; 13(3):361-6.View Related Profiles. PMID: 17334370.
  9. Schembri F, Sridhar S, Liu G, Zhang S, Brody J, Spira A. The impact of smoking on airway epithelial microRNA expression. Pulmonary Center, Boston University School of Medicine, Pathology Program, Graduate Medical Sciences, Boston University [Oral presentation, ATS]. 2007.
  10. Spira A, Beane J, Shah V, Liu G, Schembri F, Yang X, Palma J, Brody JS. Effects of cigarette smoke on the human airway epithelial cell transcriptome. Proc Natl Acad Sci U S A. 2004 Jul 6; 101(27):10143-8.View Related Profiles. PMID: 15210990; PMCID: PMC454179.
Showing 10 of 13 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 13 publications over 7 distinct years, with a maximum of 3 publications in 2004

YearPublications
19991
20043
20072
20081
20092
20112
20132
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Bronchial airway
Gene expression

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