Umit Tapan | Profiles RNS

Umit Tapan, MD

Assistant Professor

Boston University Chobanian & Avedisian School of Medicine

Medicine

Hematology & Medical Oncology

MD, Hacettepe University

Websites

	Boston Medical Center Provider Profile
	LinkedIn
	ResearchGate
	Google Scholar
	MyNCBI

ORCID : 0000-0002-3906-3004

Dr. Umit Tapan is an Assistant Professor of Medicine at Chobanian and Avedisian School of Medicine and practicing Thoracic Oncologist at Boston Medical Center. His clinical interests are Non-small cell lung cancer, Small cell lung cancer, Mesothelioma, Immunotherapy, Targeted therapy/Precision Medicine. His research interests include Circulating tumor DNA, Gut microbiome and Cancer Immunotherapy, Racial Disparities in Cancer Care and Outcomes.

Dr. Tapan completed his fellowship in Hematology & Oncology at Boston Univesity Medical Center, in which he was Chief Fellow in Hematology & Oncology. Dr. Tapan completed his internship and residency at Steward Carney Hospital. He earned his medical degree from Hacettepe University School of Medicine, Ankara, Turkey.

Diversity, Equity, Inclusion and Accessibility

I am honored to be working with my colleagues in providing exceptional care without exception. I have dedicated my research efforts to improving access to state-of-the art testing (also called "molecular profiling") and innovative treatments (including immunotherapy and personalized medicine) in lung cancer patients. I am an international medical graduate and I have been welcomed by the multicultural environment in the United States since my arrival in 2009. I strive to improve my understanding of the diverse cultures and backgrounds, in healthcare and in the society at large. Furthering the efforts to reduce disparities in lung cancer care, I have joined a National Thoracic Cancer Clinical Trial Working Group, with the goal of increasing enrollment of diverse patient populations to the clinical trials.

Member
Boston University
BU-BMC Cancer Center

Member
Boston University
Evans Center for Interdisciplinary Biomedical Research

BMC Research

SUNRAY-01, A Global Pivotal Study in Participants with KRAS G12C-Mutant, Locally Advanced or Metastatic Non-Small Cell Lung Cancer Comparing First-Line Treatment of LY3537982 and Pembrolizumab vs Placebo and Pembrolizumab in those with PD-L1 expression =5
05/06/2024 - 05/05/2027 (PI)
Lilly USA, LLC

LCMC LEADER Neoadjuvant Screening Trial: LCMC4 Evaluation of Actionable Drivers in Early Stage Lung Cancers
01/22/2024 - 01/21/2027 (PI)
Lung Cancer Research Foundation

A Phase 2, Open-Label, Parallel Cohort Study of Subcutaneous Amivantamab in Multiple Regimens in Patients with Advanced or Metastatic Solid Tumors including EGFR-mutated Non-Small Cell Lung Cancer
12/15/2023 - 12/14/2026 (PI)
Janssen Research and Development, LLC

ML41591 NAUTIKA 1
10/25/2023 - 10/24/2026 (PI)
Genentech, Inc.

Janssen 73841937NSC1001: An Open-label Phase 1/1b Study to Evaluate the Safety and Pharmacokinetics of JNJ-73841937 (Lazertinib), a Third Generation EGFR-TKI, as Monotherapy or in Combinations With JNJ-61186372, a Human Bispecific EGFR and cMet Antibody i
02/12/2021 - 09/30/2026 (PI)
Janssen Research and Development, LLC

GSK213824
07/20/2023 - 07/19/2026 (PI)
GlaxoSmithKline

MK-7684A-006-00
07/06/2023 - 07/05/2026 (PI)
Merck

SKY06/ BO42592:A Phase II/III, Randomized, Double-blind, Placebo-controlled Study of Tiragolumab in Combination with Atezolizumab Plus Pemetrexed and Carboplatin/Cisplatin Versus Pembrolizumab Plus Pemetrexed and Carboplatin/Cisplatin in Patients with Pre
09/29/2022 - 09/28/2025 (PI)
Genentech, Inc.

DF/HCC- 19-523: Pilot study of serial plasma genotyping to guide the adaptive treatment of advanced NSCLC receiving immunotherapy.
09/02/2020 - 09/01/2024 (PI)
Dana Farber Cancer Institute

MS200095-0031: A Phase II, two-arm study to investigate tepotinib combined with osimertinib in MET amplified, advanced or metastatic non-small cell lung cancer (NSCLC) harboring activating EGFR mutations and having acquired resistance to prior osimertinib
09/30/2020 - 09/29/2023 (PI)
EMD Serono Research & Development Institute

Title

Yr	Title	Project-Sub Proj	Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Burns L, Tukachinsky H, Raskina K, Huang RSP, Schrock AB, Sands J, Kulke MH, Oxnard GR, Tapan U. Real-World comprehensive genomic profiling data for diagnostic clarity in pulmonary Large-Cell neuroendocrine carcinoma. Lung Cancer. 2024 Feb; 188:107454.View Related Profiles.

Oxnard, Geoffrey
Burns, Laura
Kulke, Matthew
Tapan, Umit

PMID: 38159439

Dudipala H, Burns L, Jani CT, Radwan A, Al Omari O, Patel M, Kilic S, Zhao J, Mak K, Suzuki K, Tapan U. Disparities in Lung Cancer Clinical Trial Discussion and Enrollment at a Safety Net Hospital. Community Health Equity Res Policy. 2023 Dec 12; 2752535X231221394.View Related Profiles.

Zhao, Jenny
Mak, Kimberley
Burns, Laura
Tapan, Umit

PMID: 38087807

Burns L, Hsu CY, Whisenant JG, Marmarelis ME, Presley CJ, Reckamp KL, Khan H, Jo Fidler M, Bestvina CM, Brahmer J, Puri S, Patel JD, Halmos B, Hirsch FR, Liu SV, Costa DB, Goldberg SB, Feldman LE, Mamdani H, Puc M, Mansfield AS, Islam N, Scilla KA, Garassino MC, Horn L, Peters S, Wakelee HA, Charlot M, Tapan U. Disparities in outcomes between Black and White patients in North America with thoracic malignancies and COVID-19 infection (TERAVOLT). Lung Cancer. 2023 Dec; 186:107423.View Related Profiles.

Burns, Laura
Tapan, Umit

PMID: 37995456

Kilic S, Zhao J, Okut H, Jani CT, Radwan A, Dudipala H, Burns L, Tapan U. Disparities in US Lung Cancer Clinical Trial Enrollment. J Racial Ethn Health Disparities. 2024 Oct; 11(5):3201-3209.View Related Profiles.

Burns, Laura
Tapan, Umit

PMID: 37651069

Al Omari O, Jani C, Ahmed A, Singh H, Radwan A, Bhatt P, Walker A, Agarwal L, Goodall R, Shalhoub J, Marshall DC, Thomson CC, Salciccioli JD, Tapan U. Lung Cancer Mortality in the United States between 1999 and 2019: An Observational Analysis of Disparities by Sex and Race. Ann Am Thorac Soc. 2023 Apr; 20(4):612-616. PMID: 36476451; PMCID: PMC10112410; DOI: 10.1513/AnnalsATS.202206-510RL;

Qureshi MM, Kam A, Suzuki K, Litle V, Tapan U, Balasubramaniyan R, Dyer MA, Truong MT, Mak KS. Association between hospital safety-net burden and receipt of trimodality therapy and survival for patients with esophageal cancer. Surgery. 2023 May; 173(5):1153-1161.View Related Profiles.

Mak, Kimberley
Truong, Minh
Qureshi, Muhammad
Balasubramaniyan, Ramkumar
Tapan, Umit
Litle, Virginia

PMID: 36774317

Siddiqi N, Pan G, Liu A, Lin Y, Jenkins K, Zhao J, Mak K, Tapan U, Suzuki K. Timeliness of Lung Cancer Care From the Point of Suspicious Image at an Urban Safety Net Hospital. Clin Lung Cancer. 2023 Mar; 24(2):e87-e93.View Related Profiles.

Pan, Gilbert
Zhao, Jenny
Mak, Kimberley
Tapan, Umit

PMID: 36642641

Liu A, Siddiqi N, Tapan U, Mak KS, Steiling KA, Suzuki K. Black Race Remains Associated with Lower Eligibility for Screening Using 2021 US Preventive Services Task Force Recommendations Among Lung Cancer Patients at an Urban Safety Net Hospital. J Racial Ethn Health Disparities. 2023 Dec; 10(6):2836-2843.View Related Profiles.

Steiling, Katrina
Mak, Kimberley
Tapan, Umit

PMID: 36441493

Burns L, Jani C, Radwan A, Omari OA, Patel M, Oxnard GR, Tapan U. Implementation Challenges and Disparities in Molecular Testing for Patients With Stage IV NSCLC: Perspectives from an Urban Safety-Net Hospital. Clin Lung Cancer. 2023 Mar; 24(2):e69-e77.View Related Profiles.

Oxnard, Geoffrey
Burns, Laura
Tapan, Umit

PMID: 36464575

Edwards CV, Sheikh AR, Dennis MJ, Hunter A, Mackay ZP, Catudal EC, Elias R, Cabral HJ, Sarosiek SR, Tapan U. The impact of substance use on health care utilization, treatment, and outcomes in patients with non-small cell lung cancer. J Thorac Dis. 2022 Oct; 14(10):3865-3875.View Related Profiles.

Edwards, Camille
Catudal, Evan
Cabral, Howard
Tapan, Umit

PMID: 36389291; PMCID: PMC9641327; DOI: 10.21037/jtd-21-1992;

Showing 10 of 34 results. Show More

Lee MH, Qureshi MM, Suzuki K, Everett P, Tapan U, Mak KS. Small cell lung cancer in young patients: trends in sociodemographic factors, diagnosis, treatment, and survival. J Thorac Dis. 2022 Aug; 14(8):2880-2893.View Related Profiles.

Mak, Kimberley
Lee, Michelle
Qureshi, Muhammad
Everett, Peter
Tapan, Umit

PMID: 36071763; PMCID: PMC9442513; DOI: 10.21037/jtd-22-210;

Whisenant JG, Baena J, Cortellini A, Huang LC, Lo Russo G, Porcu L, Wong SK, Bestvina CM, Hellmann MD, Roca E, Rizvi H, Monnet I, Boudjemaa A, Rogado J, Pasello G, Leighl NB, Arrieta O, Aujayeb A, Batra U, Azzam AY, Unk M, Azab MA, Zhumagaliyeva AN, Gomez-Martin C, Blaquier JB, Geraedts E, Mountzios G, Serrano-Montero G, Reinmuth N, Coate L, Marmarelis M, Presley CJ, Hirsch FR, Garrido P, Khan H, Baggi A, Mascaux C, Halmos B, Ceresoli GL, Fidler MJ, Scotti V, Métivier AC, Falchero L, Felip E, Genova C, Mazieres J, Tapan U, Brahmer J, Bria E, Puri S, Popat S, Reckamp KL, Morgillo F, Nadal E, Mazzoni F, Agustoni F, Bar J, Grosso F, Avrillon V, Patel JD, Gomes F, Ibrahim E, Trama A, Bettini AC, Barlesi F, Dingemans AM, Wakelee H, Peters S, Horn L, Garassino MC, Torri V. A Definitive Prognostication System for Patients With Thoracic Malignancies Diagnosed With Coronavirus Disease 2019: An Update From the TERAVOLT Registry. J Thorac Oncol. 2022 May; 17(5):661-674. PMID: 35121086; PMCID: PMC8804493; DOI: 10.1016/j.jtho.2021.12.015;

Jani C, Al Omari O, Singh H, Walker A, Patel K, Mouchati C, Radwan A, Pandit Z, Hanbury G, Crowley C, Marshall DC, Goodall R, Shalhoub J, Salciccioli JD, Tapan U. Trends of HIV-Related Cancer Mortality between 2001 and 2018: An Observational Analysis. Trop Med Infect Dis. 2021 Dec 20; 6(4). PMID: 34941669; PMCID: PMC8707967; DOI: 10.3390/tropicalmed6040213;

Annesi CA, Poulson MR, Mak KS, Tapan U, Dechert TA, Litle VR, Suzuki K. The Impact of Residential Racial Segregation on Non-Small Cell Lung Cancer Treatment and Outcomes. Ann Thorac Surg. 2022 04; 113(4):1291-1298.View Related Profiles.

Suzuki, Kei
Mak, Kimberley
Poulson, Michael
Dechert, Tracey
Tapan, Umit
Litle, Virginia

PMID: 34033745

Tapan U, Furtado VF, Qureshi MM, Everett P, Suzuki K, Mak KS. Racial and Other Healthcare Disparities in Patients With Extensive-Stage SCLC. JTO Clin Res Rep. 2021 Jan; 2(1):100109.View Related Profiles.

Suzuki, Kei
Mak, Kimberley
Qureshi, Muhammad
Everett, Peter
Tapan, Umit

PMID: 34589974; PMCID: PMC8474393; DOI: 10.1016/j.jtocrr.2020.100109;

Kumaradevan S, Lee SY, Richards S, Lyle C, Zhao Q, Tapan U, Jiangliu Y, Ghumman S, Walker J, Belghasem M, Arinze N, Kuhnen A, Weinberg J, Francis J, Hartshorn K, Kolachalama VB, Cifuentes D, Rahimi N, Chitalia VC. c-Cbl Expression Correlates with Human Colorectal Cancer Survival and Its Wnt/ß-Catenin Suppressor Function Is Regulated by Tyr371 Phosphorylation. Am J Pathol. 2018 08; 188(8):1921-1933.View Related Profiles.

Kuhnen, Angela
Cifuentes, Daniel
Weinberg, Janice
Francis, Jean
Walker, Joshua
Hartshorn, Kevan
Belghasem, Mostafa
Rahimi, Nader
Arinze , Nkiruka
Zhao, Qing
Tapan, Umit
Kolachalama, Vijaya
Chitalia, Vipul

PMID: 30029779; PMCID: PMC6099425; DOI: 10.1016/j.ajpath.2018.05.007;

Tapan U, Lee SY, Weinberg J, Kolachalama VB, Francis J, Charlot M, Hartshorn K, Chitalia V. Racial differences in colorectal cancer survival at a safety net hospital. Cancer Epidemiol. 2017 08; 49:30-37.View Related Profiles.

Weinberg, Janice
Francis, Jean
Hartshorn, Kevan
Charlot, Marjory
Tapan, Umit
Kolachalama, Vijaya
Chitalia, Vipul

PMID: 28538169; PMCID: PMC5656256; DOI: 10.1016/j.canep.2017.05.003;

Shashar M, Siwak J, Tapan U, Lee SY, Meyer RD, Parrack P, Tan J, Khatami F, Francis J, Zhao Q, Hartshorn K, Kolachalama VB, Rahimi N, Chitalia V. c-Cbl mediates the degradation of tumorigenic nuclear ß-catenin contributing to the heterogeneity in Wnt activity in colorectal tumors. Oncotarget. 2016 11 01; 7(44):71136-71150.View Related Profiles.

Francis, Jean
Tan, Josenia
Hartshorn, Kevan
Rahimi, Nader
Zhao, Qing
Tapan, Umit
Kolachalama, Vijaya
Chitalia, Vipul

PMID: 27661103; PMCID: PMC5342068; DOI: 10.18632/oncotarget.12107;

Yuksel M, Yildiz A, Tapan U, Ertas F, Alan S. Resolution of Extensive Coronary Thrombosis under Rivaroxaban Treatment. Arq Bras Cardiol. 2015 Dec; 105(6):642-6. PMID: 26761372; PMCID: PMC4693669; DOI: 10.5935/abc.20150052;

Eliacik E, Yildirim T, Sahin U, Kizilarslanoglu C, Tapan U, Aybal-Kutlugun A, Hascelik G, Arici M. Potassium abnormalities in current clinical practice: frequency, causes, severity and management. Med Princ Pract. 2015; 24(3):271-5. PMID: 25766276; PMCID: PMC5588203; DOI: 10.1159/000376580;

Pamuk GE, Uyanik MS, Top MS, Tapan U, Ak R, Uyanik V. Gastrointestinal symptoms are closely associated with depression in iron deficiency anemia: a comparative study. Ann Saudi Med. 2015 Jan-Feb; 35(1):31-5. PMID: 26142935; PMCID: PMC6152543; DOI: 10.5144/0256-4947.2015.31;

Tapan U, Bolla S, Daglilar ES, Chang S, Kozyreva O. Outcome of patients with positive heparin-platelet factor-4 antibodies: A retrospective multi-institutional observational study. Platelets. 2015; 26(7):661-4.View Related Profiles.

Kozyreva, Olga
Tapan, Umit

PMID: 25383658; DOI: 10.3109/09537104.2014.977243;

Pamuk GE, Uyanik MS, Pamuk ON, Maden M, Tapan U. Decreased dickkopf-1 levels in chronic lymphocytic leukemia and increased osteopontin levels in non-Hodgkin's lymphoma at initial diagnosis: Could they be playing roles in pathogenesis? Hematology. 2015 Jun; 20(5):267-71. PMID: 25271869; DOI: 10.1179/1607845414Y.0000000205;

Tapan U, Ozbayrak M, Tatli S. MRI in local staging of rectal cancer: an update. Diagn Interv Radiol. 2014 Sep-Oct; 20(5):390-8. PMID: 25010367; PMCID: PMC4463328; DOI: 10.5152/dir.2014.13265;

Tapan U, Pestana JB, Lee JC, Lerner A. Epstein-Barr virus-associated diffuse large B-cell lymphoma arising in atrial myxoma: a proposal for a modified therapeutic approach. Leuk Lymphoma. 2015 Feb; 56(2):505-7.View Related Profiles.

Lerner, Adam
Tapan, Umit

PMID: 24794809; DOI: 10.3109/10428194.2014.919632;

Pamuk GE, Tapan U, Aksoy S, Umit H. An adult patient with common B-cell acute lymphoblastic leukaemia who presented with pancreatic involvement, description of the second adult case and review of paediatric cases. BMJ Case Rep. 2014 May 22; 2014. PMID: 24855096; PMCID: PMC4039778; DOI: 10.1136/bcr-2013-200817;

Tatli S, Tapan U, Morrison PR, Silverman SG. Radiofrequency ablation: technique and clinical applications. Diagn Interv Radiol. 2012 Sep-Oct; 18(5):508-16. PMID: 22407695

Tapan U, Kutlugun AA, Arici M, Altun B. Postural epigastric pain: a challenging symptom for cytomegalovirus (CMV) gastritis. Ren Fail. 2012; 34(2):235-6. PMID: 22251042

Tapan U, Dizdar O, Bulut N, Celik I. Multimodality treatment in the management of anorectal melanoma: a case report and review of the literature. Eurasian J Med. 2011 Dec; 43(3):189-91. PMID: 25610191; PMCID: PMC4261398; DOI: 10.5152/eajm.2011.40;

Tapan U, May SK, Fiore J, Kozyreva O. Reactivation of hepatitis B virus following bendamustine-containing chemotherapy in a patient with multiple myeloma. Leuk Lymphoma. 2011 May; 52(5):916-8.View Related Profiles.

Kozyreva, Olga
Tapan, Umit

PMID: 21306291

Tapan U, Seldin DC, Finn KT, Fennessey S, Shelton A, Zeldis JB, Sanchorawala V. Increases in B-type natriuretic peptide (BNP) during treatment with lenalidomide in AL amyloidosis. Blood. 2010 Dec 2; 116(23):5071-2.View Related Profiles.

Seldin, David
Tapan, Umit
Sanchorawala, Vaishali

PMID: 21127185; DOI: 10.1182/blood-2010-09-305136;

Serefhanoglu S, Tapan U, Ertenli I, Kalyoncu U, Uner A. Primary thyroid marginal zone B-cell lymphoma MALT-type in a patient with rheumatoid arthritis. Med Oncol. 2010 Sep; 27(3):826-32. PMID: 19705304; DOI: 10.1007/s12032-009-9293-x;

Dizdar O, Harputluoglu H, Tapan U, Altundag K. Efficacy of chemotherapy for brain metastases from breast carcinoma: in regard to Le Scodan et al. (Int J Radiat Oncol Biol Phys 2007;69:839-845). Int J Radiat Oncol Biol Phys. 2008 Apr 01; 70(5):1615. PMID: 18374237; DOI: 10.1016/j.ijrobp.2007.07.2362;

Dizdar O, Tapan U, Aksoy S, Harputluoglu H, Kilickap S, Barista I. Liver dysfunction after chemotherapy in lymphoma patients infected with hepatitis C. Eur J Haematol. 2008 May; 80(5):381-5. PMID: 18221389; DOI: 10.1111/j.1600-0609.2008.01039.x;

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 34 publications over 14 distinct years, with a maximum of 6 publications in 2022 and 2023

Bar chart showing 34 publications over 14 distinct years, with a maximum of 6 publications in 2022 and 2023

Year	Publications
2008	2
2009	1
2010	1
2011	2
2012	2
2014	5
2015	3
2016	1
2017	1
2018	1
2020	1
2021	2
2022	6
2023	6

Media Mentions

Recent (within 3 months)

Expanding Access to NSCLC Innovations: Challenges and Opportunities

AJMC 10/18/2024

Older

Racial, Socioeconomic Disparities in Extensive-Stage Small Cell Lung Cancer Treatment

Oncology Times 2/9/2022

Black Americans Don’t Get Screened or Treated for Lung Cancer at Same Rates as White Americans: Here’s Why, & What We Can Do About It

Survivor Net 2/16/2021

Racial and Other Disparities Persist Among Patients with Extensive-Stage Small Cell Lung Cancer

Cure Today 11/16/2020

Study Finds Racial and Socioeconomic Disparities in Chemo Treatment for ES-SCLC

Cancer Network 11/2/2020

Quality Data, Genetic Testing Can Reduce Cancer Care Disparities

Health IT Analytics 10/27/2020

US healthcare: Black people less likely to receive lung cancer chemotherapy

Open Access News 10/27/2020

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