Marc Lenburg, PhD
Professor
Boston University School of Medicine
Dept of Medicine
Computational Biomedicine

PhD, University of California San Francisco




Expertise in computational approaches to leverage genome-wide datasets (especially genome-wide gene-expression) for clinical and biological insight. Interests include developing and applying these tools for translational research.

Professor
Boston University School of Medicine
Pathology & Laboratory Medicine


Member
Boston University
BU-BMC Cancer Center


Member
Boston University
Pulmonary Center


Member
Boston University
Evans Center for Interdisciplinary Biomedical Research


Member
Boston University
Genome Science Institute


Member
Boston University
Bioinformatics Graduate Program


Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Graduate Medical Sciences




DECAMP 1 PLUS: Prediction of Lung Cancer Using Noninvasive Biomarkers
03/01/2019 - 03/01/2023 (Co-Investigator)
PI: Ehab Billatos, MD
Johnson & Johnson


Molecular and Imaging biomarkers for early lung cancer detection in the setting of Indeterminate Pulmonary Nodules
09/23/2016 - 08/31/2022 (PI)
NIH/National Cancer Institute
5R01CA210360-05

The Boston University-UCLA Lung Cancer Biomarker Development Lab
09/20/2016 - 08/31/2021 (PI)
NIH/National Cancer Institute
5U01CA214182-05

Integrated molecular, cellular and imaging characterization of screen-detected lung cancer
09/16/2015 - 08/31/2021 (Subcontract PI)
University of California, Los Angeles NIH NCI
5U01CA196408-05

Transitions from Impaired Respiratory Health to Lung Disease
01/01/2020 - 06/30/2021 (Subcontract PI)
Northwestern University NIH NHLBI
2R01HL122477-06A1

The American Lung Association (ALA) Lung Health Cohort
06/15/2019 - 04/30/2021 (Subcontract PI)
Northwestern University NIH NHLBI
5U01HL146408-02

Study BET inhibitors in COPD
12/18/2017 - 02/28/2019 (PI)
AstraZeneca AB


Integrative Omics to Discover Molecular Determinants of COPD
06/01/2016 - 05/31/2018 (Multi-PI)
PI: Marc Lenburg, PhD
NIH/National Heart, Lung, and Blood Institute
4R01HL118542-04

Molecular biomarkers of airway and lung linking COPD and Lung Cancer
09/15/2011 - 07/31/2016 (Multi-PI)
PI: Marc Lenburg, PhD
NIH/National Cancer Institute
5R01CA164783-04

Integrative Omics to Discover Molecular Determinants of COPD
08/15/2013 - 05/31/2016 (Multi-PI)
PI: Marc Lenburg, PhD
NIH/National Heart, Lung, and Blood Institute
5R01HL118542-03

Showing 10 of 11 results. Show All Results


Title


Yr Title Project-Sub Proj Pubs
2021 Molecular and Imaging Biomarkers for Early Lung Cancer Detection in the Setting of Indeterminate Pulmonary Nodules 5R01CA210360-06 4
2021 The Boston University-UCLA Lung Cancer Biomarker Development Lab 3U01CA214182-05S1 7
2020 Molecular and Imaging Biomarkers for Early Lung Cancer Detection in the Setting of Indeterminate Pulmonary Nodules 5R01CA210360-05 4
2020 The Boston University-UCLA Lung Cancer Biomarker Development Lab 5U01CA214182-05 7
2020 Integrated Molecular, Cellular, and Imaging Characterization of Screen-Detected Lung Cancer 3U01CA196408-05S1 7
2019 Molecular and Imaging Biomarkers for Early Lung Cancer Detection in the Setting of Indeterminate Pulmonary Nodules 5R01CA210360-04 4
2019 The Boston University-UCLA Lung Cancer Biomarker Development Lab 5U01CA214182-04 7
2019 Integrated Molecular, Cellular, and Imaging Characterization of Screen-Detected Lung Cancer 5U01CA196408-05 7
2018 Data Processing, Analysis, and Modeling Unit 1U2CCA233238-01-8065 1
2018 Molecular and Imaging Biomarkers for Early Lung Cancer Detection in the Setting of Indeterminate Pulmonary Nodules 5R01CA210360-03 4
Showing 10 of 38 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Maoz A, Merenstein C, Koga Y, Potter A, Gower AC, Liu G, Zhang S, Liu H, Stevenson C, Spira A, Reid ME, Campbell JD, Mazzilli SA, Lenburg ME, Beane J. Elevated T cell repertoire diversity is associated with progression of lung squamous cell premalignant lesions. J Immunother Cancer. 2021 Sep; 9(9).View Related Profiles. PMID: 34580161; PMCID: PMC8477334; DOI: 10.1136/jitc-2021-002647;
     
  2. Hicks-Berthet J, Ning B, Federico A, Tilston-Lunel A, Matschulat A, Ai X, Lenburg ME, Beane J, Monti S, Varelas X. Yap/Taz inhibit goblet cell fate to maintain lung epithelial homeostasis. Cell Rep. 2021 Jul 13; 36(2):109347.View Related Profiles. PMID: 34260916; PMCID: PMC8346236; DOI: 10.1016/j.celrep.2021.109347;
     
  3. Becker EJ, Faiz A, van den Berge M, Timens W, Hiemstra PS, Clark K, Liu G, Xiao X, Alekseyev YO, O'Connor G, Lam S, Spira A, Lenburg ME, Steiling K. Bronchial gene expression signature associated with rate of subsequent FEV1 decline in individuals with and at risk of COPD. Thorax. 2021 May 10.View Related Profiles. PMID: 33972452
     
  4. Xu F, Tanabe N, Vasilescu DM, McDonough JE, Coxson HO, Ikezoe K, Kinose D, Ng KW, Verleden SE, Wuyts WA, Vanaudenaerde BM, Verschakelen J, Cooper JD, Lenburg ME, Morshead KB, Abbas AR, Arron JR, Spira A, Hackett TL, Colby TV, Ryerson CJ, Ng RT, Hogg JC. The transition from normal lung anatomy to minimal and established fibrosis in idiopathic pulmonary fibrosis (IPF). EBioMedicine. 2021 Apr; 66:103325.View Related Profiles. PMID: 33862585; PMCID: PMC8054143; DOI: 10.1016/j.ebiom.2021.103325;
     
  5. Choi Y, Qu J, Wu S, Hao Y, Zhang J, Ning J, Yang X, Lofaro L, Pankratz DG, Babiarz J, Walsh PS, Billatos E, Lenburg ME, Kennedy GC, McAuliffe J, Huang J. Improving lung cancer risk stratification leveraging whole transcriptome RNA sequencing and machine learning across multiple cohorts. BMC Med Genomics. 2020 10 22; 13(Suppl 10):151.View Related Profiles. PMID: 33087128; PMCID: PMC7579926; DOI: 10.1186/s12920-020-00782-1;
     
  6. Faiz A, Imkamp K, van der Wiel E, Boudewijn IM, Koppelman GH, Brandsma CA, Kerstjens HAM, Timens W, Vroegop S, Pasma HR, Boersma WG, Wielders P, van den Elshout F, Mansour K, Steiling K, Spira A, Lenburg ME, Heijink IH, Postma DS, van den Berge M. Identifying a nasal gene expression signature associated with hyperinflation and treatment response in severe COPD. Sci Rep. 2020 10 15; 10(1):17415.View Related Profiles. PMID: 33060632; PMCID: PMC7562702; DOI: 10.1038/s41598-020-72551-0;
     
  7. Billatos E, Ash SY, Duan F, Xu K, Romanoff J, Marques H, Moses E, Han MK, Regan EA, Bowler RP, Mason SE, Doyle TJ, San José Estépar R, Rosas IO, Ross JC, Xiao X, Liu H, Liu G, Sukumar G, Wilkerson M, Dalgard C, Stevenson C, Whitney D, Aberle D, Spira A, San José Estépar R, Lenburg ME, Washko GR. Distinguishing Smoking-Related Lung Disease Phenotypes Via Imaging and Molecular Features. Chest. 2021 02; 159(2):549-563.View Related Profiles. PMID: 32946850; PMCID: PMC8039011; DOI: 10.1016/j.chest.2020.08.2115;
     
  8. Drizik E, Corbett S, Zheng Y, Vermeulen R, Dai Y, Hu W, Ren D, Duan H, Niu Y, Xu J, Fu W, Meliefste K, Zhou B, Zhang X, Yang J, Bassig B, Liu H, Ye M, Liu G, Jia X, Meng T, Bin P, Zhang J, Silverman D, Spira A, Rothman N, Lenburg ME, Lan Q. Transcriptomic changes in the nasal epithelium associated with diesel engine exhaust exposure. Environ Int. 2020 04; 137:105506.View Related Profiles. PMID: 32044442
     
  9. Hickson LJ, Langhi Prata LGP, Bobart SA, Evans TK, Giorgadze N, Hashmi SK, Herrmann SM, Jensen MD, Jia Q, Jordan KL, Kellogg TA, Khosla S, Koerber DM, Lagnado AB, Lawson DK, LeBrasseur NK, Lerman LO, McDonald KM, McKenzie TJ, Passos JF, Pignolo RJ, Pirtskhalava T, Saadiq IM, Schaefer KK, Textor SC, Victorelli SG, Volkman TL, Xue A, Wentworth MA, Wissler Gerdes EO, Allison DB, Dickinson SL, Ejima K, Atkinson EJ, Lenburg M, Zhu Y, Tchkonia T, Kirkland JL. Corrigendum to 'Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease' EBioMedicine 47 (2019) 446-456. EBioMedicine. 2020 Feb; 52:102595. PMID: 31982828; PMCID: PMC6994619; DOI: 10.1016/j.ebiom.2019.12.004;
     
  10. Duclos GE, Teixeira VH, Autissier P, Gesthalter YB, Reinders-Luinge MA, Terrano R, Dumas YM, Liu G, Mazzilli SA, Brandsma CA, van den Berge M, Janes SM, Timens W, Lenburg ME, Spira A, Campbell JD, Beane J. Characterizing smoking-induced transcriptional heterogeneity in the human bronchial epithelium at single-cell resolution. Sci Adv. 2019 12; 5(12):eaaw3413.View Related Profiles. PMID: 31844660; PMCID: PMC6905872; DOI: 10.1126/sciadv.aaw3413;
     
Showing 10 of 187 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 187 publications over 24 distinct years, with a maximum of 22 publications in 2012

YearPublications
19921
19931
19942
19961
20011
20031
20041
20054
20063
20077
20088
200913
201013
201120
201222
201311
201416
201516
201615
201714
20183
20195
20205
20214
Contact for Mentoring:

75 E. Newton St Evans Building
Boston MA 02118
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