Marc Lenburg, PhD
Professor
Boston University School of Medicine
Dept of Medicine
Computational Biomedicine

PhD, University of California San Francisco




Expertise in computational approaches to leverage genome-wide datasets (especially genome-wide gene-expression) for clinical and biological insight. Interests include developing and applying these tools for translational research.

Professor
Boston University School of Medicine
Pathology & Laboratory Medicine


Member
Boston University
BU-BMC Cancer Center


Member
Boston University
Pulmonary Center


Member
Boston University
Evans Center for Interdisciplinary Biomedical Research


Member
Boston University
Genome Science Institute


Member
Boston University
Bioinformatics Graduate Program


Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Graduate Medical Sciences




DECAMP 1 PLUS: Prediction of Lung Cancer Using Noninvasive Biomarkers
03/01/2019 - 03/01/2023 (Co-PI)
PI: Ehab Billatos, MD
Johnson & Johnson


Molecular and Imaging biomarkers for early lung cancer detection in the setting of Indeterminate Pulmonary Nodules
09/23/2016 - 08/31/2022 (PI)
NIH/National Cancer Institute
5R01CA210360-05

The Boston University-UCLA Lung Cancer Biomarker Development Lab
09/20/2016 - 08/31/2021 (PI)
NIH/National Cancer Institute
5U01CA214182-05

The American Lung Association (ALA) Lung Health Cohort
06/15/2019 - 04/30/2021 (Subcontract PI)
Northwestern University NIH NHLBI
5U01HL146408-02

Transitions from Impaired Respiratory Health to Lung Disease
01/01/2020 - 12/31/2020 (Subcontract PI)
Northwestern University NIH NHLBI
2R01HL122477-06A1

Integrated molecular, cellular and imaging characterization of screen-detected lung cancer
09/16/2015 - 08/31/2020 (Subcontract PI)
University of California, Los Angeles NIH NCI
5U01CA196408-05

Study BET inhibitors in COPD
12/18/2017 - 02/28/2019 (PI)
AstraZeneca AB


Integrative Omics to Discover Molecular Determinants of COPD
06/01/2016 - 05/31/2018 (Multi-PI)
PI: Marc Lenburg, PhD
NIH/National Heart, Lung, and Blood Institute
4R01HL118542-04

Molecular biomarkers of airway and lung linking COPD and Lung Cancer
09/15/2011 - 07/31/2016 (Multi-PI)
PI: Marc Lenburg, PhD
NIH/National Cancer Institute
5R01CA164783-04

Integrative Omics to Discover Molecular Determinants of COPD
08/15/2013 - 05/31/2016 (Multi-PI)
PI: Marc Lenburg, PhD
NIH/National Heart, Lung, and Blood Institute
5R01HL118542-03

Showing 10 of 11 results. Show All Results


Title


Yr Title Project-Sub Proj Pubs
2020 Molecular and Imaging Biomarkers for Early Lung Cancer Detection in the Setting of Indeterminate Pulmonary Nodules 5R01CA210360-05 4
2020 The Boston University-UCLA Lung Cancer Biomarker Development Lab 5U01CA214182-05 7
2020 Integrated Molecular, Cellular, and Imaging Characterization of Screen-Detected Lung Cancer 3U01CA196408-05S1 7
2019 Molecular and Imaging Biomarkers for Early Lung Cancer Detection in the Setting of Indeterminate Pulmonary Nodules 5R01CA210360-04 4
2019 The Boston University-UCLA Lung Cancer Biomarker Development Lab 5U01CA214182-04 7
2018 Data Processing, Analysis, and Modeling Unit 1U2CCA233238-01-8065 1
2018 Molecular and Imaging Biomarkers for Early Lung Cancer Detection in the Setting of Indeterminate Pulmonary Nodules 5R01CA210360-03 4
2018 The Boston University-UCLA Lung Cancer Biomarker Development Lab 5U01CA214182-03 7
2017 Molecular and Imaging Biomarkers for Early Lung Cancer Detection in the Setting of Indeterminate Pulmonary Nodules 5R01CA210360-02 4
2017 The Boston University-UCLA Lung Cancer Biomarker Development Lab 5U01CA214182-02 7
Showing 10 of 35 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Choi Y, Qu J, Wu S, Hao Y, Zhang J, Ning J, Yang X, Lofaro L, Pankratz DG, Babiarz J, Walsh PS, Billatos E, Lenburg ME, Kennedy GC, McAuliffe J, Huang J. Improving lung cancer risk stratification leveraging whole transcriptome RNA sequencing and machine learning across multiple cohorts. BMC Med Genomics. 2020 Oct 22; 13(Suppl 10):151.View Related Profiles. PMID: 33087128
     
  2. Faiz A, Imkamp K, van der Wiel E, Boudewijn IM, Koppelman GH, Brandsma CA, Kerstjens HAM, Timens W, Vroegop S, Pasma HR, Boersma WG, Wielders P, van den Elshout F, Mansour K, Steiling K, Spira A, Lenburg ME, Heijink IH, Postma DS, van den Berge M. Identifying a nasal gene expression signature associated with hyperinflation and treatment response in severe COPD. Sci Rep. 2020 10 15; 10(1):17415.View Related Profiles. PMID: 33060632
     
  3. Billatos E, Ash SY, Duan F, Xu K, Romanoff J, Marques H, Moses E, Han MK, Regan EA, Bowler RP, Mason SE, Doyle TJ, San José Estépar R, Rosas IO, Ross JC, Xiao X, Liu H, Liu G, Sukumar G, Wilkerson M, Dalgard C, Stevenson C, Whitney D, Aberle D, Spira A, San José Estépar R, Lenburg ME, Washko GR. Distinguishing Smoking-Related Lung Disease Phenotypes Via Imaging and Molecular Features. Chest. 2020 Sep 16.View Related Profiles. PMID: 32946850
     
  4. Drizik E, Corbett S, Zheng Y, Vermeulen R, Dai Y, Hu W, Ren D, Duan H, Niu Y, Xu J, Fu W, Meliefste K, Zhou B, Zhang X, Yang J, Bassig B, Liu H, Ye M, Liu G, Jia X, Meng T, Bin P, Zhang J, Silverman D, Spira A, Rothman N, Lenburg ME, Lan Q. Transcriptomic changes in the nasal epithelium associated with diesel engine exhaust exposure. Environ Int. 2020 04; 137:105506.View Related Profiles. PMID: 32044442
     
  5. Hickson LJ, Langhi Prata LGP, Bobart SA, Evans TK, Giorgadze N, Hashmi SK, Herrmann SM, Jensen MD, Jia Q, Jordan KL, Kellogg TA, Khosla S, Koerber DM, Lagnado AB, Lawson DK, LeBrasseur NK, Lerman LO, McDonald KM, McKenzie TJ, Passos JF, Pignolo RJ, Pirtskhalava T, Saadiq IM, Schaefer KK, Textor SC, Victorelli SG, Volkman TL, Xue A, Wentworth MA, Wissler Gerdes EO, Allison DB, Dickinson SL, Ejima K, Atkinson EJ, Lenburg M, Zhu Y, Tchkonia T, Kirkland JL. Corrigendum to 'Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease' EBioMedicine 47 (2019) 446-456. EBioMedicine. 2020 Feb; 52:102595. PMID: 31982828
     
  6. Duclos GE, Teixeira VH, Autissier P, Gesthalter YB, Reinders-Luinge MA, Terrano R, Dumas YM, Liu G, Mazzilli SA, Brandsma CA, van den Berge M, Janes SM, Timens W, Lenburg ME, Spira A, Campbell JD, Beane J. Characterizing smoking-induced transcriptional heterogeneity in the human bronchial epithelium at single-cell resolution. Sci Adv. 2019 12; 5(12):eaaw3413.View Related Profiles. PMID: 31844660
     
  7. Corbett SE, Nitzberg M, Moses E, Kleerup E, Wang T, Perdomo C, Perdomo C, Liu G, Xiao X, Liu H, Elashoff DA, Brooks DR, O'Connor GT, Dubinett SM, Spira A, Lenburg ME. Gene Expression Alterations in the Bronchial Epithelium of e-Cigarette Users. Chest. 2019 10; 156(4):764-773.View Related Profiles. PMID: 31233743
     
  8. Hijazi K, Malyszko B, Steiling K, Xiao X, Liu G, Alekseyev YO, Dumas YM, Hertsgaard L, Jensen J, Hatsukami D, Brooks DR, O'Connor G, Beane J, Lenburg ME, Spira A. Tobacco-Related Alterations in Airway Gene Expression are Rapidly Reversed Within Weeks Following Smoking-Cessation. Sci Rep. 2019 05 06; 9(1):6978.View Related Profiles. PMID: 31061400
     
  9. Faiz A, Steiling K, Roffel MP, Postma DS, Spira A, Lenburg ME, Borggrewe M, Eijgenraam TR, Jonker MR, Koppelman GH, Pouwels SD, Liu G, Alekseyev YO, Lam S, Hiemstra PS, Sterk PJ, Timens W, Brandsma CA, Heijink IH, van den Berge M. Effect of long-term corticosteroid treatment on microRNA and gene-expression profiles in COPD. Eur Respir J. 2019 04; 53(4).View Related Profiles. PMID: 30846474
     
  10. Beane JE, Mazzilli SA, Campbell JD, Duclos G, Krysan K, Moy C, Perdomo C, Schaffer M, Liu G, Zhang S, Liu H, Vick J, Dhillon SS, Platero SJ, Dubinett SM, Stevenson C, Reid ME, Lenburg ME, Spira AE. Molecular subtyping reveals immune alterations associated with progression of bronchial premalignant lesions. Nat Commun. 2019 04 23; 10(1):1856.View Related Profiles. PMID: 31015447
     
Showing 10 of 183 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 183 publications over 23 distinct years, with a maximum of 22 publications in 2012

YearPublications
19921
19931
19942
19961
20011
20031
20041
20054
20063
20077
20088
200913
201013
201120
201222
201311
201416
201516
201615
201714
20183
20195
20205

Contact for Mentoring:

75 E. Newton St Evans Building
Boston MA 02118
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