Marc Lenburg, PhD
Professor
Boston University School of Medicine
Dept of Medicine
Computational Biomedicine

PhD, University of California San Francisco




Expertise in computational approaches to leverage genome-wide datasets (especially genome-wide gene-expression) for clinical and biological insight. Interests include developing and applying these tools for translational research.

Professor
Boston University School of Medicine
Pathology & Laboratory Medicine


Member
Boston University
BU-BMC Cancer Center


Member
Boston University
Pulmonary Center


Member
Boston University
Evans Center for Interdisciplinary Biomedical Research


Member
Boston University
Genome Science Institute


Member
Boston University
Bioinformatics Graduate Program


Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Graduate Medical Sciences




DECAMP 1 PLUS: Prediction of Lung Cancer Using Noninvasive Biomarkers
03/01/2019 - 03/01/2023 (Co-Investigator)
PI: Ehab Billatos, MD
Johnson & Johnson


Improving Outcomes After Lung Cancer Surgery
01/01/2022 - 12/31/2022 (PI)
Ellison Foundation


The Boston University-UCLA Lung Cancer Biomarker Development Lab
09/20/2016 - 09/30/2022 (PI)
NIH/National Cancer Institute
3U01CA214182-05S1

Molecular and Imaging biomarkers for early lung cancer detection in the setting of Indeterminate Pulmonary Nodules
09/23/2016 - 08/31/2022 (PI)
NIH/National Cancer Institute
5R01CA210360-06

Transitions from Impaired Respiratory Health to Lung Disease
01/01/2020 - 06/30/2022 (Subcontract PI)
Northwestern University NIH NHLBI
5R01HL122477-07

The American Lung Association (ALA) Lung Health Cohort
06/15/2019 - 04/30/2022 (Subcontract PI)
Northwestern University NIH NHLBI
5U01HL146408-03

Integrated molecular, cellular and imaging characterization of screen-detected lung cancer
09/16/2015 - 08/31/2021 (Subcontract PI)
University of California, Los Angeles NIH NCI
3U01CA196408-05S1

Study BET inhibitors in COPD
12/18/2017 - 02/28/2019 (PI)
AstraZeneca AB


Integrative Omics to Discover Molecular Determinants of COPD
06/01/2016 - 05/31/2018 (Multi-PI)
PI: Marc Lenburg, PhD
NIH/National Heart, Lung, and Blood Institute
4R01HL118542-04

Molecular biomarkers of airway and lung linking COPD and Lung Cancer
09/15/2011 - 07/31/2016 (Multi-PI)
PI: Marc Lenburg, PhD
NIH/National Cancer Institute
5R01CA164783-04

Showing 10 of 12 results. Show All Results


Title


Yr Title Project-Sub Proj Pubs
2022 The Boston University - UCLA Lung Cancer Biomarker Characterization Center 1U2CCA271898-01
2022 Admin Core 1U2CCA271898-01-5084
2021 Molecular and Imaging Biomarkers for Early Lung Cancer Detection in the Setting of Indeterminate Pulmonary Nodules 5R01CA210360-06 4
2021 The Boston University-UCLA Lung Cancer Biomarker Development Lab 3U01CA214182-05S1 7
2020 Molecular and Imaging Biomarkers for Early Lung Cancer Detection in the Setting of Indeterminate Pulmonary Nodules 5R01CA210360-05 4
2020 The Boston University-UCLA Lung Cancer Biomarker Development Lab 5U01CA214182-05 7
2020 Integrated Molecular, Cellular, and Imaging Characterization of Screen-Detected Lung Cancer 3U01CA196408-05S1 7
2019 Molecular and Imaging Biomarkers for Early Lung Cancer Detection in the Setting of Indeterminate Pulmonary Nodules 5R01CA210360-04 4
2019 The Boston University-UCLA Lung Cancer Biomarker Development Lab 5U01CA214182-04 7
2019 Integrated Molecular, Cellular, and Imaging Characterization of Screen-Detected Lung Cancer 5U01CA196408-05 7
Showing 10 of 40 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Xu F, Vasilescu DM, Kinose D, Tanabe N, Ng KW, Coxson HO, Cooper JD, Hackett TL, Verleden SE, Vanaudenaerde BM, Stevenson CS, Lenburg ME, Spira A, Tan WC, Sin DD, Ng RT, Hogg JC. The molecular and cellular mechanisms associated with the destruction of terminal bronchioles in COPD. Eur Respir J. 2022 May; 59(5).View Related Profiles. PMID: 34675046
     
  2. You X, Dadwal UC, Lenburg ME, Kacena MA, Charles JF. Murine Gut Microbiome Meta-analysis Reveals Alterations in Carbohydrate Metabolism in Response to Aging. mSystems. 2022 Apr 26; 7(2):e0124821. PMID: 35400171; PMCID: PMC9040766; DOI: 10.1128/msystems.01248-21;
     
  3. Lu D, Demissie S, Horowitz NB, Gower AC, Lenburg ME, Alekseyev YO, Hussein AI, Bragdon B, Liu Y, Daukss D, Page JM, Webster MZ, Schlezinger JJ, Morgan EF, Gerstenfeld LC. Temporal and Quantitative Transcriptomic Differences Define Sexual Dimorphism in Murine Postnatal Bone Aging. JBMR Plus. 2022 Feb; 6(2):e10579.View Related Profiles. PMID: 35229061; PMCID: PMC8861981; DOI: 10.1002/jbm4.10579;
     
  4. Burks EJ, Zhang J, Sullivan TB, Shi X, Sands JM, Regis SM, McKee BJ, McKee AB, Zhang S, Liu H, Liu G, Spira A, Beane J, Lenburg ME, Rieger-Christ KM. Pathologic and gene expression comparison of CT- screen detected and routinely detected stage I/0 lung adenocarcinoma in NCCN risk-matched cohorts. Cancer Treat Res Commun. 2021; 29:100486.View Related Profiles. PMID: 34794107; PMCID: PMC8713084; DOI: 10.1016/j.ctarc.2021.100486;
     
  5. Xu K, Shi X, Husted C, Hong R, Wang Y, Ning B, Sullivan T, Rieger-Christ K, Duan F, Marques H, Gower A, Xiao X, Liu H, Liu G, Duclos G, Platt M, Spira A, Mazzilli S, Billatos E, Lenburg M, Campbell J, Beane J. Smoking Modulates Different Secretory Subpopulations Expressing SARS-CoV-2 Entry Genes in the Nasal and Bronchial Airways. Res Sq. 2021 Oct 28.View Related Profiles. PMID: 34729557; PMCID: PMC8562543; DOI: 10.21203/rs.3.rs-887718/v1;
     
  6. Maoz A, Merenstein C, Koga Y, Potter A, Gower AC, Liu G, Zhang S, Liu H, Stevenson C, Spira A, Reid ME, Campbell JD, Mazzilli SA, Lenburg ME, Beane J. Elevated T cell repertoire diversity is associated with progression of lung squamous cell premalignant lesions. J Immunother Cancer. 2021 09; 9(9).View Related Profiles. PMID: 34580161; PMCID: PMC8477334; DOI: 10.1136/jitc-2021-002647;
     
  7. Hicks-Berthet J, Ning B, Federico A, Tilston-Lunel A, Matschulat A, Ai X, Lenburg ME, Beane J, Monti S, Varelas X. Yap/Taz inhibit goblet cell fate to maintain lung epithelial homeostasis. Cell Rep. 2021 07 13; 36(2):109347.View Related Profiles. PMID: 34260916; PMCID: PMC8346236; DOI: 10.1016/j.celrep.2021.109347;
     
  8. Becker EJ, Faiz A, van den Berge M, Timens W, Hiemstra PS, Clark K, Liu G, Xiao X, Alekseyev YO, O'Connor G, Lam S, Spira A, Lenburg ME, Steiling K. Bronchial gene expression signature associated with rate of subsequent FEV1 decline in individuals with and at risk of COPD. Thorax. 2022 01; 77(1):31-39.View Related Profiles. PMID: 33972452
     
  9. Xu F, Tanabe N, Vasilescu DM, McDonough JE, Coxson HO, Ikezoe K, Kinose D, Ng KW, Verleden SE, Wuyts WA, Vanaudenaerde BM, Verschakelen J, Cooper JD, Lenburg ME, Morshead KB, Abbas AR, Arron JR, Spira A, Hackett TL, Colby TV, Ryerson CJ, Ng RT, Hogg JC. The transition from normal lung anatomy to minimal and established fibrosis in idiopathic pulmonary fibrosis (IPF). EBioMedicine. 2021 Apr; 66:103325.View Related Profiles. PMID: 33862585; PMCID: PMC8054143; DOI: 10.1016/j.ebiom.2021.103325;
     
  10. Choi Y, Qu J, Wu S, Hao Y, Zhang J, Ning J, Yang X, Lofaro L, Pankratz DG, Babiarz J, Walsh PS, Billatos E, Lenburg ME, Kennedy GC, McAuliffe J, Huang J. Improving lung cancer risk stratification leveraging whole transcriptome RNA sequencing and machine learning across multiple cohorts. BMC Med Genomics. 2020 10 22; 13(Suppl 10):151.View Related Profiles. PMID: 33087128; PMCID: PMC7579926; DOI: 10.1186/s12920-020-00782-1;
     
Showing 10 of 192 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 192 publications over 25 distinct years, with a maximum of 22 publications in 2012

YearPublications
19921
19931
19942
19961
20011
20031
20041
20054
20063
20077
20088
200913
201013
201120
201222
201311
201416
201516
201615
201714
20183
20195
20205
20217
20222
Contact for Mentoring:

75 E. Newton St Evans Building
Boston MA 02118
Google Map


Lenburg's Networks
Click the "See All" links for more information and interactive visualizations
Concepts
_
Media Mentions
_
Co-Authors
_
Similar People
_
Same Department