Marc Lenburg, PhD
Professor
Boston University Chobanian & Avedisian School of Medicine
Medicine
Computational Biomedicine

PhD, University of California San Francisco
BA, Wesleyan University

Pronouns: he/him/his



Expertise in computational approaches to leverage genome-wide datasets (especially genome-wide gene-expression) for clinical and biological insight. Interests include developing and applying these tools for translational research.

Professor
Boston University Chobanian & Avedisian School of Medicine
Pathology & Laboratory Medicine


Member
Boston University
BU-BMC Cancer Center


Member
Boston University
Pulmonary Center


Member
Boston University
Evans Center for Interdisciplinary Biomedical Research


Member
Boston University
Genome Science Institute


Member
Boston University
Bioinformatics Graduate Program


Graduate Faculty (Primary Mentor of Grad Students)
Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences




Integrating imaging and biopsy-derived molecular markers for the pre-surgical detection of indolent and aggressive early stage lung adenocarcinoma
07/10/2023 - 06/30/2028 (PI)
NIH/National Cancer Institute
1R01CA275015-01A1

The Boston University - UCLA Lung Cancer Biomarker Characterization Center
09/01/2022 - 07/31/2027 (Multi-PI)
PI: Marc Lenburg, PhD
NIH/National Cancer Institute
5U2CCA271898-02

The Boston University Clinical and Transitional Science Institute
04/15/2020 - 03/31/2025 (Key Person)
PI: Megan H. Bair-Merritt, MD, MSCE
NIH/National Center for Advancing Translational Sciences
3UL1TR001430-08S1

Sequencing of nasal RNA from individuals at high risk for lung cancer
01/01/2023 - 12/31/2024 (PI)
Inova Health Care Services


Transitions from Impaired Respiratory Health to Lung Disease
01/01/2020 - 06/30/2024 (Subcontract PI)
Northwestern University NIH NHLBI
5R01HL122477-07

The American Lung Association (ALA) Lung Health Cohort
06/15/2019 - 06/30/2024 (Subcontract PI)
Northwestern University NIH NHLBI
5U01HL146408-05

Improving Outcomes After Lung Cancer Surgery
01/01/2022 - 12/31/2023 (PI)
Ellison Foundation


mRNA expression sequencing analysis of nasal swabs from workers exposed to electronic waste processing in Accra, Ghana (CAS: 10821)
09/21/2022 - 09/20/2023 (PI)
NIH/National Cancer Institute
75N91022P00843

Impact of smoking and its cessation on systemic and airway immune activation
07/01/2022 - 08/31/2023 (Subcontract PI)
Boston Medical Center Corporation NIH NIDA
5 R01 DA042685-05

Molecular and Imaging biomarkers for early lung cancer detection in the setting of Indeterminate Pulmonary Nodules
09/23/2016 - 08/31/2023 (PI)
NIH/National Cancer Institute
5R01CA210360-06

Showing 10 of 18 results. Show All Results


Title


Yr Title Project-Sub Proj Pubs
2023 Integrating imaging and biopsy-derived molecular markers for the pre-surgical detection of indolent and aggressive early stage lung adenocarcinoma 1R01CA275015-01A1
2023 The Boston University - UCLA Lung Cancer Biomarker Characterization Center 5U2CCA271898-02
2023 Admin Core 5U2CCA271898-02-6879
2022 Admin Core 1U2CCA271898-01-5084
2022 The Boston University - UCLA Lung Cancer Biomarker Characterization Center 1U2CCA271898-01
2021 Molecular and Imaging Biomarkers for Early Lung Cancer Detection in the Setting of Indeterminate Pulmonary Nodules 5R01CA210360-06 4
2021 The Boston University-UCLA Lung Cancer Biomarker Development Lab 3U01CA214182-05S1 7
2020 Molecular and Imaging Biomarkers for Early Lung Cancer Detection in the Setting of Indeterminate Pulmonary Nodules 5R01CA210360-05 4
2020 The Boston University-UCLA Lung Cancer Biomarker Development Lab 5U01CA214182-05 7
2020 Integrated Molecular, Cellular, and Imaging Characterization of Screen-Detected Lung Cancer 3U01CA196408-05S1 7
Showing 10 of 43 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Menon AA, Lee M, Ke X, Putman RK, Hino T, Rose JA, Duan F, Ash SY, Cho MH, O'Connor GT, Dupuis J, Hatabu H, Lenburg ME, Billatos ES, Hunninghake GM. Bronchial epithelial gene expression and interstitial lung abnormalities. Respir Res. 2023 Oct 10; 24(1):245.View Related Profiles. PMID: 37817229; PMCID: PMC10566143; DOI: 10.1186/s12931-023-02536-w;
     
  2. Yanagawa J, Tran LM, Salehi-Rad R, Lim RJ, Dumitras C, Fung E, Wallace WD, Prosper AE, Fishbein G, Shea C, Hong R, Kahangi B, Deng JJ, Gower AC, Liu B, Campbell JD, Mazzilli SA, Beane JE, Kadara H, Lenburg ME, Spira AE, Aberle DR, Krysan K, Dubinett SM. Single-Cell Characterization of Pulmonary Nodules Implicates Suppression of Immunosurveillance across Early Stages of Lung Adenocarcinoma. Cancer Res. 2023 Oct 02; 83(19):3305-3319.View Related Profiles. PMID: 37477508; PMCID: PMC10544016; DOI: 10.1158/0008-5472.CAN-23-0128;
     
  3. Pavel AB, Garrison C, Luo L, Liu G, Taub D, Xiao J, Juan-Guardela B, Tedrow J, Alekseyev YO, Yang IV, Geraci MW, Sciurba F, Schwartz DA, Kaminski N, Beane J, Spira A, Lenburg ME, Campbell JD. Integrative genetic and genomic networks identify microRNA associated with COPD and ILD. Sci Rep. 2023 Aug 11; 13(1):13076.View Related Profiles. PMID: 37567908; PMCID: PMC10421936; DOI: 10.1038/s41598-023-39751-w;
     
  4. Paez R, Kammer MN, Tanner NT, Shojaee S, Heideman BE, Peikert T, Balbach ML, Iams WT, Ning B, Lenburg ME, Mallow C, Yarmus L, Fong KM, Deppen S, Grogan EL, Maldonado F. Update on Biomarkers for the Stratification of Indeterminate Pulmonary Nodules. Chest. 2023 Oct; 164(4):1028-1041. PMID: 37244587; PMCID: PMC10645597; DOI: 10.1016/j.chest.2023.05.025;
     
  5. Ning B, Tilston-Lunel AM, Simonetti J, Hicks-Berthet J, Matschulat A, Pfefferkorn R, Spira A, Edwards M, Mazzilli S, Lenburg ME, Beane JE, Varelas X. Convergence of YAP/TAZ, TEAD and TP63 activity is associated with bronchial premalignant severity and progression. J Exp Clin Cancer Res. 2023 May 08; 42(1):116.View Related Profiles. PMID: 37150829; PMCID: PMC10165825; DOI: 10.1186/s13046-023-02674-5;
     
  6. Kammer MN, Mori H, Rowe DJ, Chen SC, Vasiukov G, Atwater T, Senosain MF, Antic S, Zou Y, Chen H, Peikert T, Deppen S, Grogan EL, Massion PP, Dubinett S, Lenburg M, Borowsky A, Maldonado F. Tumoral Densities of T-Cells and Mast Cells Are Associated With Recurrence in Early-Stage Lung Adenocarcinoma. JTO Clin Res Rep. 2023 Sep; 4(9):100504. PMID: 37674811; PMCID: PMC10477685; DOI: 10.1016/j.jtocrr.2023.100504;
     
  7. Xu K, Diaz AA, Duan F, Lee M, Xiao X, Liu H, Liu G, Cho MH, Gower AC, Alekseyev YO, Spira A, Aberle DR, Washko GR, Billatos E, Lenburg ME. Bronchial gene expression alterations associated with radiological bronchiectasis. Eur Respir J. 2023 Jan; 61(1).View Related Profiles. PMID: 36229050; PMCID: PMC9881226; DOI: 10.1183/13993003.00120-2022;
     
  8. Kern JG, Tilston-Lunel AM, Federico A, Ning B, Mueller A, Peppler GB, Stampouloglou E, Cheng N, Johnson RL, Lenburg ME, Beane JE, Monti S, Varelas X. Inactivation of LATS1/2 drives luminal-basal plasticity to initiate basal-like mammary carcinomas. Nat Commun. 2022 Nov 28; 13(1):7198.View Related Profiles. PMID: 36443313; PMCID: PMC9705439; DOI: 10.1038/s41467-022-34864-8;
     
  9. Moreira JD, Gower AC, Xue L, Alekseyev Y, Smith KK, Choi SH, Ayalon N, Farb MG, Tenan K, LeClerc A, Levy D, Benjamin EJ, Lenburg ME, Mitchell RN, Padera RF, Fetterman JL, Gopal DM. Systematic dissection, preservation, and multiomics in whole human and bovine hearts. Cardiovasc Pathol. 2023; 63:107495.View Related Profiles. PMID: 36334690; PMCID: PMC10031913; DOI: 10.1016/j.carpath.2022.107495;
     
  10. Xu K, Shi X, Husted C, Hong R, Wang Y, Ning B, Sullivan TB, Rieger-Christ KM, Duan F, Marques H, Gower AC, Xiao X, Liu H, Liu G, Duclos G, Platt M, Spira AE, Mazzilli SA, Billatos E, Lenburg ME, Campbell JD, Beane JE. Smoking modulates different secretory subpopulations expressing SARS-CoV-2 entry genes in the nasal and bronchial airways. Sci Rep. 2022 Oct 28; 12(1):18168.View Related Profiles. PMID: 36307504; PMCID: PMC9615627; DOI: 10.1038/s41598-022-17832-6;
     
Showing 10 of 202 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 202 publications over 26 distinct years, with a maximum of 22 publications in 2012

YearPublications
19921
19931
19942
19961
20011
20031
20041
20054
20063
20077
20088
200913
201013
201120
201222
201311
201416
201516
201615
201714
20183
20195
20205
20217
20225
20237
Contact for Mentoring:

75 E. Newton St Evans Building
Boston MA 02118
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