Marc Lenburg, PhD
Professor
Boston University Chobanian & Avedisian School of Medicine
Medicine
Computational Biomedicine

PhD, University of California San Francisco
BA, Wesleyan University

Pronouns: he/him/his



Expertise in computational approaches to leverage genome-wide datasets (especially genome-wide gene-expression) for clinical and biological insight. Interests include developing and applying these tools for translational research.

Professor
Boston University Chobanian & Avedisian School of Medicine
Pathology & Laboratory Medicine


Member
Boston University
BU-BMC Cancer Center


Member
Boston University
Pulmonary Center


Member
Boston University
Evans Center for Interdisciplinary Biomedical Research


Member
Boston University
Genome Science Institute


Member
Boston University
Bioinformatics Graduate Program


Graduate Faculty (Primary Mentor of Grad Students)
Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences




The Boston University - UCLA Lung Cancer Biomarker Characterization Center
09/01/2022 - 07/31/2027 (Multi-PI)
PI: Marc Lenburg, PhD
NIH/National Cancer Institute
1U2CCA271898-01

The Boston University Clinical and Transitional Science Institute
04/15/2020 - 03/31/2025 (Key Person)
PI: Megan H. Bair-Merritt, MD, MSCE
NIH/National Center for Advancing Translational Sciences
3UL1TR001430-07S1

Improving Outcomes After Lung Cancer Surgery
01/01/2022 - 12/31/2023 (PI)
Ellison Foundation


mRNA expression sequencing analysis of nasal swabs from workers exposed to electronic waste processing in Accra, Ghana (CAS: 10821)
09/21/2022 - 09/20/2023 (PI)
NIH/National Cancer Institute
75N91022P00843

Molecular and Imaging biomarkers for early lung cancer detection in the setting of Indeterminate Pulmonary Nodules
09/23/2016 - 08/31/2023 (PI)
NIH/National Cancer Institute
5R01CA210360-06

Impact of smoking and its cessation on systemic and airway immune activation
07/01/2022 - 06/30/2023 (Subcontract PI)
Boston Medical Center Corporation NIH NIDA
5 R01 DA042685-05

Transitions from Impaired Respiratory Health to Lung Disease
01/01/2020 - 06/30/2023 (Subcontract PI)
Northwestern University NIH NHLBI
5R01HL122477-07

The American Lung Association (ALA) Lung Health Cohort
06/15/2019 - 06/30/2023 (Subcontract PI)
Northwestern University NIH NHLBI
5U01HL146408-04

DECAMP 1 PLUS: Prediction of Lung Cancer Using Noninvasive Biomarkers
03/01/2019 - 03/01/2023 (Co-Investigator)
PI: Ehab Billatos, MD
Johnson & Johnson


The Boston University-UCLA Lung Cancer Biomarker Development Lab
09/20/2016 - 09/30/2022 (PI)
NIH/National Cancer Institute
3U01CA214182-05S1

Showing 10 of 16 results. Show All Results


Title


Yr Title Project-Sub Proj Pubs
2022 The Boston University - UCLA Lung Cancer Biomarker Characterization Center 1U2CCA271898-01
2022 Admin Core 1U2CCA271898-01-5084
2021 Molecular and Imaging Biomarkers for Early Lung Cancer Detection in the Setting of Indeterminate Pulmonary Nodules 5R01CA210360-06 4
2021 The Boston University-UCLA Lung Cancer Biomarker Development Lab 3U01CA214182-05S1 7
2020 Molecular and Imaging Biomarkers for Early Lung Cancer Detection in the Setting of Indeterminate Pulmonary Nodules 5R01CA210360-05 4
2020 The Boston University-UCLA Lung Cancer Biomarker Development Lab 5U01CA214182-05 7
2020 Integrated Molecular, Cellular, and Imaging Characterization of Screen-Detected Lung Cancer 3U01CA196408-05S1 7
2019 Molecular and Imaging Biomarkers for Early Lung Cancer Detection in the Setting of Indeterminate Pulmonary Nodules 5R01CA210360-04 4
2019 The Boston University-UCLA Lung Cancer Biomarker Development Lab 5U01CA214182-04 7
2019 Integrated Molecular, Cellular, and Imaging Characterization of Screen-Detected Lung Cancer 5U01CA196408-05 7
Showing 10 of 40 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Ning B, Tilston-Lunel AM, Simonetti J, Hicks-Berthet J, Matschulat A, Pfefferkorn R, Spira A, Edwards M, Mazzilli S, Lenburg ME, Beane JE, Varelas X. Convergence of YAP/TAZ, TEAD and TP63 activity is associated with bronchial premalignant severity and progression. J Exp Clin Cancer Res. 2023 May 08; 42(1):116.View Related Profiles. PMID: 37150829; PMCID: PMC10165825; DOI: 10.1186/s13046-023-02674-5;
     
  2. Xu K, Diaz AA, Duan F, Lee M, Xiao X, Liu H, Liu G, Cho MH, Gower AC, Alekseyev YO, Spira A, Aberle DR, Washko GR, Billatos E, Lenburg ME. Bronchial gene expression alterations associated with radiological bronchiectasis. Eur Respir J. 2023 Jan; 61(1).View Related Profiles. PMID: 36229050; PMCID: PMC9881226; DOI: 10.1183/13993003.00120-2022;
     
  3. Kern JG, Tilston-Lunel AM, Federico A, Ning B, Mueller A, Peppler GB, Stampouloglou E, Cheng N, Johnson RL, Lenburg ME, Beane JE, Monti S, Varelas X. Inactivation of LATS1/2 drives luminal-basal plasticity to initiate basal-like mammary carcinomas. Nat Commun. 2022 Nov 28; 13(1):7198.View Related Profiles. PMID: 36443313; PMCID: PMC9705439; DOI: 10.1038/s41467-022-34864-8;
     
  4. Moreira JD, Gower AC, Xue L, Alekseyev Y, Smith KK, Choi SH, Ayalon N, Farb MG, Tenan K, LeClerc A, Levy D, Benjamin EJ, Lenburg ME, Mitchell RN, Padera RF, Fetterman JL, Gopal DM. Systematic dissection, preservation, and multiomics in whole human and bovine hearts. Cardiovasc Pathol. 2023; 63:107495.View Related Profiles. PMID: 36334690; PMCID: PMC10031913; DOI: 10.1016/j.carpath.2022.107495;
     
  5. Xu K, Shi X, Husted C, Hong R, Wang Y, Ning B, Sullivan TB, Rieger-Christ KM, Duan F, Marques H, Gower AC, Xiao X, Liu H, Liu G, Duclos G, Platt M, Spira AE, Mazzilli SA, Billatos E, Lenburg ME, Campbell JD, Beane JE. Smoking modulates different secretory subpopulations expressing SARS-CoV-2 entry genes in the nasal and bronchial airways. Sci Rep. 2022 Oct 28; 12(1):18168.View Related Profiles. PMID: 36307504; PMCID: PMC9615627; DOI: 10.1038/s41598-022-17832-6;
     
  6. Xu F, Vasilescu DM, Kinose D, Tanabe N, Ng KW, Coxson HO, Cooper JD, Hackett TL, Verleden SE, Vanaudenaerde BM, Stevenson CS, Lenburg ME, Spira A, Tan WC, Sin DD, Ng RT, Hogg JC. The molecular and cellular mechanisms associated with the destruction of terminal bronchioles in COPD. Eur Respir J. 2022 May; 59(5).View Related Profiles. PMID: 34675046
     
  7. You X, Dadwal UC, Lenburg ME, Kacena MA, Charles JF. Murine Gut Microbiome Meta-analysis Reveals Alterations in Carbohydrate Metabolism in Response to Aging. mSystems. 2022 Apr 26; 7(2):e0124821. PMID: 35400171; PMCID: PMC9040766; DOI: 10.1128/msystems.01248-21;
     
  8. Lu D, Demissie S, Horowitz NB, Gower AC, Lenburg ME, Alekseyev YO, Hussein AI, Bragdon B, Liu Y, Daukss D, Page JM, Webster MZ, Schlezinger JJ, Morgan EF, Gerstenfeld LC. Temporal and Quantitative Transcriptomic Differences Define Sexual Dimorphism in Murine Postnatal Bone Aging. JBMR Plus. 2022 Feb; 6(2):e10579.View Related Profiles. PMID: 35229061; PMCID: PMC8861981; DOI: 10.1002/jbm4.10579;
     
  9. Burks EJ, Zhang J, Sullivan TB, Shi X, Sands JM, Regis SM, McKee BJ, McKee AB, Zhang S, Liu H, Liu G, Spira A, Beane J, Lenburg ME, Rieger-Christ KM. Pathologic and gene expression comparison of CT- screen detected and routinely detected stage I/0 lung adenocarcinoma in NCCN risk-matched cohorts. Cancer Treat Res Commun. 2021; 29:100486.View Related Profiles. PMID: 34794107; PMCID: PMC8713084; DOI: 10.1016/j.ctarc.2021.100486;
     
  10. Xu K, Shi X, Husted C, Hong R, Wang Y, Ning B, Sullivan T, Rieger-Christ K, Duan F, Marques H, Gower A, Xiao X, Liu H, Liu G, Duclos G, Platt M, Spira A, Mazzilli S, Billatos E, Lenburg M, Campbell J, Beane J. Smoking Modulates Different Secretory Subpopulations Expressing SARS-CoV-2 Entry Genes in the Nasal and Bronchial Airways. Res Sq. 2021 Oct 28.View Related Profiles. PMID: 34729557; PMCID: PMC8562543; DOI: 10.21203/rs.3.rs-887718/v1;
     
Showing 10 of 197 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 197 publications over 26 distinct years, with a maximum of 22 publications in 2012

YearPublications
19921
19931
19942
19961
20011
20031
20041
20054
20063
20077
20088
200913
201013
201120
201222
201311
201416
201516
201615
201714
20183
20195
20205
20217
20225
20232
Contact for Mentoring:

75 E. Newton St Evans Building
Boston MA 02118
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