Marc Lenburg, PhD
Professor
Boston University School of Medicine
Dept of Medicine
Computational Biomedicine

PhD, University of California San Francisco




Expertise in computational approaches to leverage genome-wide datasets (especially genome-wide gene-expression) for clinical and biological insight. Interests include developing and applying these tools for translational research.

Professor
Boston University School of Medicine
Pathology & Laboratory Medicine


Member
Boston University
BU-BMC Cancer Center


Member
Boston University
Pulmonary Center


Member
Boston University
Evans Center for Interdisciplinary Biomedical Research


Member
Boston University
Genome Science Institute


Member
Boston University
Bioinformatics Graduate Program


Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Graduate Medical Sciences




DECAMP 1 PLUS: Prediction of Lung Cancer Using Noninvasive Biomarkers
03/01/2019 - 03/01/2023 (Co-PI)
PI: Ehab Billatos, MD
Johnson & Johnson


Molecular and Imaging biomarkers for early lung cancer detection in the setting of Indeterminate Pulmonary Nodules
09/23/2016 - 08/31/2022 (PI)
NIH/National Cancer Institute
5R01CA210360-04

The Boston University-UCLA Lung Cancer Biomarker Development Lab
09/20/2016 - 08/31/2021 (PI)
NIH/National Cancer Institute
5U01CA214182-04

The American Lung Association (ALA) Lung Health Cohort
06/15/2019 - 04/30/2020 (Subcontract PI)
Northwestern University NIH NHLBI
1U01HL146408-01

Study BET inhibitors in COPD
12/18/2017 - 02/28/2019 (PI)
AstraZeneca AB


Integrative Omics to Discover Molecular Determinants of COPD
06/01/2016 - 05/31/2018 (Multi-PI)
PI: Marc Lenburg, PhD
NIH/National Heart, Lung, and Blood Institute
4R01HL118542-04

Molecular biomarkers of airway and lung linking COPD and Lung Cancer
09/15/2011 - 07/31/2016 (Multi-PI)
PI: Marc Lenburg, PhD
NIH/National Cancer Institute
5R01CA164783-04

Integrative Omics to Discover Molecular Determinants of COPD
08/15/2013 - 05/31/2016 (Multi-PI)
PI: Marc Lenburg, PhD
NIH/National Heart, Lung, and Blood Institute
5R01HL118542-03

Validation of a Genomic Biomarker of Responses to Environmental Tobacco Smoke
08/08/2011 - 06/30/2015 (Multi-PI)
PI: Marc Lenburg, PhD
NIH/National Institute of Environmental Health Sciences
5R01ES020425-02



Title


Yr Title Project-Sub Proj Pubs
2019 Molecular and Imaging Biomarkers for Early Lung Cancer Detection in the Setting of Indeterminate Pulmonary Nodules 5R01CA210360-04 4
2019 The Boston University-UCLA Lung Cancer Biomarker Development Lab 5U01CA214182-04 7
2018 Data Processing, Analysis, and Modeling Unit 1U2CCA233238-01-8065 1
2018 Molecular and Imaging Biomarkers for Early Lung Cancer Detection in the Setting of Indeterminate Pulmonary Nodules 5R01CA210360-03 4
2018 The Boston University-UCLA Lung Cancer Biomarker Development Lab 5U01CA214182-03 7
2017 Molecular and Imaging Biomarkers for Early Lung Cancer Detection in the Setting of Indeterminate Pulmonary Nodules 5R01CA210360-02 4
2017 The Boston University-UCLA Lung Cancer Biomarker Development Lab 5U01CA214182-02 7
2016 Molecular and Imaging Biomarkers for Early Lung Cancer Detection in the Setting of Indeterminate Pulmonary Nodules 1R01CA210360-01 4
2016 The Boston University-UCLA Lung Cancer Biomarker Development Lab 1U01CA214182-01 7
2016 Integrative Omics to Discover Molecular Determinants of COPD 4R01HL118542-04 4
Showing 10 of 32 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Drizik E, Corbett S, Zheng Y, Vermeulen R, Dai Y, Hu W, Ren D, Duan H, Niu Y, Xu J, Fu W, Meliefste K, Zhou B, Zhang X, Yang J, Bassig B, Liu H, Ye M, Liu G, Jia X, Meng T, Bin P, Zhang J, Silverman D, Spira A, Rothman N, Lenburg ME, Lan Q. Transcriptomic changes in the nasal epithelium associated with diesel engine exhaust exposure. Environ Int. 2020 Apr; 137:105506.View Related Profiles. PMID: 32044442
     
  2. Hickson LJ, Langhi Prata LGP, Bobart SA, Evans TK, Giorgadze N, Hashmi SK, Herrmann SM, Jensen MD, Jia Q, Jordan KL, Kellogg TA, Khosla S, Koerber DM, Lagnado AB, Lawson DK, LeBrasseur NK, Lerman LO, McDonald KM, McKenzie TJ, Passos JF, Pignolo RJ, Pirtskhalava T, Saadiq IM, Schaefer KK, Textor SC, Victorelli SG, Volkman TL, Xue A, Wentworth MA, Wissler Gerdes EO, Allison DB, Dickinson SL, Ejima K, Atkinson EJ, Lenburg M, Zhu Y, Tchkonia T, Kirkland JL. Corrigendum to 'Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease' EBioMedicine 47 (2019) 446-456. EBioMedicine. 2020 Feb; 52:102595. PMID: 31982828
     
  3. Duclos GE, Teixeira VH, Autissier P, Gesthalter YB, Reinders-Luinge MA, Terrano R, Dumas YM, Liu G, Mazzilli SA, Brandsma CA, van den Berge M, Janes SM, Timens W, Lenburg ME, Spira A, Campbell JD, Beane J. Characterizing smoking-induced transcriptional heterogeneity in the human bronchial epithelium at single-cell resolution. Sci Adv. 2019 12; 5(12):eaaw3413.View Related Profiles. PMID: 31844660
     
  4. Corbett SE, Nitzberg M, Moses E, Kleerup E, Wang T, Perdomo C, Perdomo C, Liu G, Xiao X, Liu H, Elashoff DA, Brooks DR, O'Connor GT, Dubinett SM, Spira A, Lenburg ME. Gene Expression Alterations in the Bronchial Epithelium of e-Cigarette Users. Chest. 2019 10; 156(4):764-773.View Related Profiles. PMID: 31233743
     
  5. Hijazi K, Malyszko B, Steiling K, Xiao X, Liu G, Alekseyev YO, Dumas YM, Hertsgaard L, Jensen J, Hatsukami D, Brooks DR, O'Connor G, Beane J, Lenburg ME, Spira A. Tobacco-Related Alterations in Airway Gene Expression are Rapidly Reversed Within Weeks Following Smoking-Cessation. Sci Rep. 2019 05 06; 9(1):6978.View Related Profiles. PMID: 31061400
     
  6. Faiz A, Steiling K, Roffel MP, Postma DS, Spira A, Lenburg ME, Borggrewe M, Eijgenraam TR, Jonker MR, Koppelman GH, Pouwels SD, Liu G, Alekseyev YO, Lam S, Hiemstra PS, Sterk PJ, Timens W, Brandsma CA, Heijink IH, van den Berge M. Effect of long-term corticosteroid treatment on microRNA and gene-expression profiles in COPD. Eur Respir J. 2019 04; 53(4).View Related Profiles. PMID: 30846474
     
  7. Beane JE, Mazzilli SA, Campbell JD, Duclos G, Krysan K, Moy C, Perdomo C, Schaffer M, Liu G, Zhang S, Liu H, Vick J, Dhillon SS, Platero SJ, Dubinett SM, Stevenson C, Reid ME, Lenburg ME, Spira AE. Molecular subtyping reveals immune alterations associated with progression of bronchial premalignant lesions. Nat Commun. 2019 04 23; 10(1):1856.View Related Profiles. PMID: 31015447
     
  8. Billatos E, Faiz A, Gesthalter Y, LeClerc A, Alekseyev YO, Xiao X, Liu G, Ten Hacken NHT, Heijink IH, Timens W, Brandsma CA, Postma DS, van den Berge M, Spira A, Lenburg ME. Impact of acute exposure to cigarette smoke on airway gene expression. Physiol Genomics. 2018 09 01; 50(9):705-713.View Related Profiles. PMID: 29932825
     
  9. Billatos E, Vick JL, Lenburg ME, Spira AE. The Airway Transcriptome as a Biomarker for Early Lung Cancer Detection. Clin Cancer Res. 2018 07 01; 24(13):2984-2992.View Related Profiles. PMID: 29463557
     
  10. Mazzilli SA, Zhang S, Liu G, Lenburg M, Spira A, Beane J. Abstract B18: The carcinogen-induced NTCU model: A preclinical mouse model for lung cancer interception. Cancer Research. 2018; 78(10 suppl):B18. View Publication
Showing 10 of 180 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 180 publications over 23 distinct years, with a maximum of 22 publications in 2012

YearPublications
19921
19931
19942
19961
20011
20031
20041
20054
20063
20077
20088
200913
201013
201120
201222
201311
201416
201516
201615
201714
20183
20195
20202

Contact for Mentoring:

75 E. Newton St Evans Building
Boston MA 02118
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