Keywords
Last Name

Louis C. Gerstenfeld, PhD

TitleProfessor
InstitutionBoston University School of Medicine
DepartmentOrthopaedic Surgery
Address72 E. Concord St Housman (R)
Boston MA 02118
Phone(617) 414-1660
ORCID ORCID Icon0000-0002-0477-1211
Other Positions
TitleGraduate Faculty (Primary Mentor of Grad Students)
InstitutionBoston University School of Medicine, Division of Graduate Medical Sciences

TitleResearch Professor
InstitutionBoston University School of Medicine
DepartmentBiochemistry

 Research Expertise & Professional Interests
My expertise is in the area of skeletal tissue biology. I have studied skeletal biology for more than 30 years and have broad knowledge across many areas in the field, including metabolic bone disease and orthopedic-related diseases. I have carried out numerous preclinical assessments of pharmacological compounds as they relate to safety and efficacy in the treatment of fracture and osteoporosis. I have expertise in skeletal tissue structure and the histomorphometric assessment of skeletal tissues. I was among the first four labs in the United States to develop in vitro osteoblast cultures and helped to establish the standard time dependent sequence of osteogenic differentiation in vitro. My laboratory also was one of four to initially isolate the proteins and clone the major extracellular matrix proteins of bone. I have served on the NIH IRG for Orthopedics, NASA review panels for skeletal tissue biology and the DOD review panels for orthopedic related research.

 Self-Described Keywords
  • Bone Histomorphometry
  • Cell Biology of Skeletal Tissues
  • Extracellular Matrix
  • Fracture Healing
  • Osteoporosis
 Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Baker AH, Wu TH, Bolt AM, Gerstenfeld LC, Mann KK, Schlezinger JJ. Tributyltin alters the bone marrow microenvironment and suppresses B cell development. Toxicol Sci. 2017 Apr 07. PMID: 28398592.
    View in: PubMed
  2. Lim JC, Ko KI, Mattos M, Fang M, Zhang C, Feinberg D, Sindi H, Li S, Alblowi J, Kayal RA, Einhorn TA, Gerstenfeld LC, Graves DT. TNFa contributes to diabetes impaired angiogenesis in fracture healing. Bone. 2017 Mar 08; 99:26-38. PMID: 28285015.
    View in: PubMed
  3. Ko FC, Martins JS, Reddy P, Bragdon B, Hussein AI, Gerstenfeld LC, Demay MB. Acute Phosphate Restriction Impairs Bone Formation and Increases Marrow Adipose Tissue in Growing Mice. J Bone Miner Res. 2016 Dec; 31(12):2204-2214. PMID: 27324177.
    View in: PubMed
  4. Morgan EF, Pittman J, DeGiacomo A, Cusher D, de Bakker CM, Mroszczyk KA, Grinstaff MW, Gerstenfeld LC. BMPR1A antagonist differentially affects cartilage and bone formation during fracture healing. J Orthop Res. 2016 Dec; 34(12):2096-2105. PMID: 26990682.
    View in: PubMed
  5. Alsofi L, Daley E, Hornstra I, Morgan EF, Mason ZD, Acevedo JF, Word RA, Gerstenfeld LC, Trackman PC. Sex-Linked Skeletal Phenotype of Lysyl Oxidase Like-1 Mutant Mice. Calcif Tissue Int. 2016 Feb; 98(2):172-85. PMID: 26538021.
    View in: PubMed
  6. Baker AH, Watt J, Huang CK, Gerstenfeld LC, Schlezinger JJ. Tributyltin engages multiple nuclear receptor pathways and suppresses osteogenesis in bone marrow multipotent stromal cells. Chem Res Toxicol. 2015 Jun 15; 28(6):1156-66. PMID: 25932594.
    View in: PubMed
  7. Galatz LM, Gerstenfeld L, Heber-Katz E, Rodeo SA. Tendon regeneration and scar formation: The concept of scarless healing. J Orthop Res. 2015 Jun; 33(6):823-31. PMID: 25676657.
    View in: PubMed
  8. Miller GJ, Gerstenfeld LC, Morgan EF. Mechanical microenvironments and protein expression associated with formation of different skeletal tissues during bone healing. Biomech Model Mechanobiol. 2015 Nov; 14(6):1239-53. PMID: 25822264.
    View in: PubMed
  9. Bragdon B, Lybrand K, Gerstenfeld L. Overview of biological mechanisms and applications of three murine models of bone repair: closed fracture with intramedullary fixation, distraction osteogenesis, and marrow ablation by reaming. Curr Protoc Mouse Biol. 2015; 5(1):21-34. PMID: 25727198.
    View in: PubMed
  10. Lybrand K, Bragdon B, Gerstenfeld L. Mouse models of bone healing: fracture, marrow ablation, and distraction osteogenesis. Curr Protoc Mouse Biol. 2015; 5(1):35-49. PMID: 25727199.
    View in: PubMed
  11. Bragdon B, Burns R, Baker AH, Belkina AC, Morgan EF, Denis GV, Gerstenfeld LC, Schlezinger JJ. Intrinsic Sex-Linked Variations in Osteogenic and Adipogenic Differentiation Potential of Bone Marrow Multipotent Stromal Cells. J Cell Physiol. 2015 Feb; 230(2):296-307. PMID: 24962433.
    View in: PubMed
  12. Ko KI, Coimbra LS, Tian C, Alblowi J, Kayal RA, Einhorn TA, Gerstenfeld LC, Pignolo RJ, Graves DT. Diabetes reduces mesenchymal stem cells in fracture healing through a TNFa-mediated mechanism. Diabetologia. 2015 Mar; 58(3):633-42. PMID: 25563724.
    View in: PubMed
  13. Einhorn TA, Gerstenfeld LC. Fracture healing: mechanisms and interventions. Nat Rev Rheumatol. 2015 Jan; 11(1):45-54. PMID: 25266456.
    View in: PubMed
  14. Al-Sebaei MO, Daukss DM, Belkina AC, Kakar S, Wigner NA, Cusher D, Graves D, Einhorn T, Morgan E, Gerstenfeld LC. Role of Fas and Treg cells in fracture healing as characterized in the fas-deficient (lpr) mouse model of lupus. J Bone Miner Res. 2014 Jun; 29(6):1478-91. PMID: 24677136.
    View in: PubMed
  15. De Giacomo A, Morgan EF, Gerstenfeld LC. Generation of closed transverse fractures in small animals. Methods Mol Biol. 2014; 1130:35-44. PMID: 24482163.
    View in: PubMed
  16. Morgan EF, De Giacomo A, Gerstenfeld LC. Overview of skeletal repair (fracture healing and its assessment). Methods Mol Biol. 2014; 1130:13-31. PMID: 24482162.
    View in: PubMed
  17. Wigner NA, Soung do Y, Einhorn TA, Drissi H, Gerstenfeld LC. Functional role of Runx3 in the regulation of aggrecan expression during cartilage development. J Cell Physiol. 2013 Nov; 228(11):2232-42. PMID: 23625810.
    View in: PubMed
  18. Marsell R, Steen B, Bais MV, Mortlock DP, Einhorn TA, Gerstenfeld LC. Skeletal trauma generates systemic BMP2 activation that is temporally related to the mobilization of CD73+ cells. J Orthop Res. 2014 Jan; 32(1):17-23. PMID: 24018651.
    View in: PubMed
  19. Alblowi J, Tian C, Siqueira MF, Kayal RA, McKenzie E, Behl Y, Gerstenfeld L, Einhorn TA, Graves DT. Chemokine expression is upregulated in chondrocytes in diabetic fracture healing. Bone. 2013 Mar; 53(1):294-300. PMID: 23262028.
    View in: PubMed
  20. Sagi HC, Young ML, Gerstenfeld L, Einhorn TA, Tornetta P. Qualitative and quantitative differences between bone graft obtained from the medullary canal (with a Reamer/Irrigator/Aspirator) and the iliac crest of the same patient. J Bone Joint Surg Am. 2012 Dec 5; 94(23):2128-35. PMID: 23224383.
    View in: PubMed
  21. Hayward LN, de Bakker CM, Gerstenfeld LC, Grinstaff MW, Morgan EF. Assessment of contrast-enhanced computed tomography for imaging of cartilage during fracture healing. J Orthop Res. 2013 Apr; 31(4):567-73. PMID: 23165442.
    View in: PubMed
  22. Clarkin CE, Gerstenfeld LC. VEGF and bone cell signalling: an essential vessel for communication? Cell Biochem Funct. 2013 Jan; 31(1):1-11. PMID: 23129289.
    View in: PubMed
  23. Morgan EF, Hussein AI, Al-Awadhi BA, Hogan DE, Matsubara H, Al-Alq Z, Fitch J, Andre B, Hosur K, Gerstenfeld LC. Vascular development during distraction osteogenesis proceeds by sequential intramuscular arteriogenesis followed by intraosteal angiogenesis. Bone. 2012 Sep; 51(3):535-45. PMID: 22617817.
    View in: PubMed
  24. Carroll SH, Wigner NA, Kulkarni N, Johnston-Cox H, Gerstenfeld LC, Ravid K. A2B adenosine receptor promotes mesenchymal stem cell differentiation to osteoblasts and bone formation in vivo. J Biol Chem. 2012 May 4; 287(19):15718-27. PMID: 22403399.
    View in: PubMed
  25. Wigner NA, Kulkarni N, Yakavonis M, Young M, Tinsley B, Meeks B, Einhorn TA, Gerstenfeld LC. Urine matrix metalloproteinases (MMPs) as biomarkers for the progression of fracture healing. Injury. 2012 Mar; 43(3):274-8. PMID: 21689817.
    View in: PubMed
  26. Matsubara H, Hogan DE, Morgan EF, Mortlock DP, Einhorn TA, Gerstenfeld LC. Vascular tissues are a primary source of BMP2 expression during bone formation induced by distraction osteogenesis. Bone. 2012 Jul; 51(1):168-80. PMID: 22391215.
    View in: PubMed
  27. Bais MV, Shabin ZM, Young M, Einhorn TA, Kotton DN, Gerstnefeld LC. Role of Nanog in the maintenance of marrow stromal stem cells during post natal bone regeneration. Biochem Biophys Res Commun. 2012 Jan 6; 417(1):211-6. PMID: 22142851.
    View in: PubMed
  28. Grimes R, Jepsen KJ, Fitch JL, Einhorn TA, Gerstenfeld LC. The transcriptome of fracture healing defines mechanisms of coordination of skeletal and vascular development during endochondral bone formation. J Bone Miner Res. 2011 Nov; 26(11):2597-609. PMID: 21826735.
    View in: PubMed
  29. Hayward LN, de Bakker CM, Lusic H, Gerstenfeld LC, Grinstaff MW, Morgan EF. MRT letter: Contrast-enhanced computed tomographic imaging of soft callus formation in fracture healing. Microsc Res Tech. 2012 Jan; 75(1):7-14. PMID: 22038692.
    View in: PubMed
  30. Bauzá G, Miller G, Kaseje N, Wigner NA, Wang Z, Gerstenfeld LC, Burke PA. The effects of injury magnitude on the kinetics of the acute phase response. J Trauma. 2011 Apr; 70(4):948-53. PMID: 20693926.
    View in: PubMed
  31. Baloul SS, Gerstenfeld LC, Morgan EF, Carvalho RS, Van Dyke TE, Kantarci A. Mechanism of action and morphologic changes in the alveolar bone in response to selective alveolar decortication-facilitated tooth movement. Am J Orthod Dentofacial Orthop. 2011 Apr; 139(4 Suppl):S83-101. PMID: 21435543.
    View in: PubMed
  32. Siqueira MF, Flowers S, Bhattacharya R, Faibish D, Behl Y, Kotton DN, Gerstenfeld L, Moran E, Graves DT. FOXO1 modulates osteoblast differentiation. Bone. 2011 May 1; 48(5):1043-51. PMID: 21281751.
    View in: PubMed
  33. Iftikhar M, Hurtado P, Bais MV, Wigner N, Stephens DN, Gerstenfeld LC, Trackman PC. Lysyl oxidase-like-2 (LOXL2) is a major isoform in chondrocytes and is critically required for differentiation. J Biol Chem. 2011 Jan 14; 286(2):909-18. PMID: 21071451.
    View in: PubMed
  34. Kayal RA, Siqueira M, Alblowi J, McLean J, Krothapalli N, Faibish D, Einhorn TA, Gerstenfeld LC, Graves DT. TNF-alpha mediates diabetes-enhanced chondrocyte apoptosis during fracture healing and stimulates chondrocyte apoptosis through FOXO1. J Bone Miner Res. 2010 Jul; 25(7):1604-15. PMID: 20200974.
    View in: PubMed
  35. Wigner NA, Luderer HF, Cox MK, Sooy K, Gerstenfeld LC, Demay MB. Acute phosphate restriction leads to impaired fracture healing and resistance to BMP-2. J Bone Miner Res. 2010 Apr; 25(4):724-33. PMID: 19839770.
    View in: PubMed
  36. Salisbury Palomares KT, Gerstenfeld LC, Wigner NA, Lenburg ME, Einhorn TA, Morgan EF. Transcriptional profiling and biochemical analysis of mechanically induced cartilaginous tissues in a rat model. Arthritis Rheum. 2010 Apr; 62(4):1108-18. PMID: 20131271.
    View in: PubMed
  37. Gerstenfeld LC, McLean J, Healey DS, Stapleton SN, Silkman LJ, Price C, Jepsen KJ. Genetic variation in the structural pattern of osteoclast activity during post-natal growth of mouse femora. Bone. 2010 Jun; 46(6):1546-54. PMID: 20178867.
    View in: PubMed
  38. Steen, B, Gerstenfeld, LC , and Einhorn, TA. Chapter 12: The Role of the Immune System in Fracture Healing 2010. Osteoimmunology (ed by Joseph Lorenzo, Yongwon Choi, Mark Horowitz and Hiroshi Takayanagi ). Elsevier. Amsterdam, Netherlands. 2010.
  39. Evans CH, Liu FJ, Glatt V, Hoyland JA, Kirker-Head C, Walsh A, Betz O, Wells JW, Betz V, Porter RM, Saad FA, Gerstenfeld LC, Einhorn TA, Harris MB, Vrahas MS. Use of genetically modified muscle and fat grafts to repair defects in bone and cartilage. Eur Cell Mater. 2009; 18:96-111. PMID: 20073015.
    View in: PubMed
  40. Alblowi J, Kayal RA, Siqueira M, Siqueria M, McKenzie E, Krothapalli N, McLean J, Conn J, Nikolajczyk B, Einhorn TA, Gerstenfeld L, Graves DT. High levels of tumor necrosis factor-alpha contribute to accelerated loss of cartilage in diabetic fracture healing. Am J Pathol. 2009 Oct; 175(4):1574-85. PMID: 19745063.
    View in: PubMed
  41. Palomares KT, Gleason RE, Mason ZD, Cullinane DM, Einhorn TA, Gerstenfeld LC, Morgan EF. Mechanical stimulation alters tissue differentiation and molecular expression during bone healing. J Orthop Res. 2009 Sep; 27(9):1123-32. PMID: 19242967.
    View in: PubMed
  42. Bais M, McLean J, Sebastiani P, Young M, Wigner N, Smith T, Kotton DN, Einhorn TA, Gerstenfeld LC. Transcriptional analysis of fracture healing and the induction of embryonic stem cell-related genes. PLoS One. 2009; 4(5):e5393. PMID: 19415118.
    View in: PubMed
  43. Bais MV, Wigner N, Young M, Toholka R, Graves DT, Morgan EF, Gerstenfeld LC, Einhorn TA. BMP2 is essential for post natal osteogenesis but not for recruitment of osteogenic stem cells. Bone. 2009 Aug; 45(2):254-66. PMID: 19398045.
    View in: PubMed
  44. Gerstenfeld LC, Sacks DJ, Pelis M, Mason ZD, Graves DT, Barrero M, Ominsky MS, Kostenuik PJ, Morgan EF, Einhorn TA. Comparison of effects of the bisphosphonate alendronate versus the RANKL inhibitor denosumab on murine fracture healing. J Bone Miner Res. 2009 Feb; 24(2):196-208. PMID: 19016594.
    View in: PubMed
  45. Hunter DJ, Gerstenfeld L, Bishop G, Davis AD, Mason ZD, Einhorn TA, Maciewicz RA, Newham P, Foster M, Jackson S, Morgan EF. Bone marrow lesions from osteoarthritis knees are characterized by sclerotic bone that is less well mineralized. Arthritis Res Ther. 2009; 11(1):R11. PMID: 19171047.
    View in: PubMed
  46. Kayal RA, Alblowi J, McKenzie E, Krothapalli N, Silkman L, Gerstenfeld L, Einhorn TA, Graves DT. Diabetes causes the accelerated loss of cartilage during fracture repair which is reversed by insulin treatment. Bone. 2009 Feb; 44(2):357-63. PMID: 19010456.
    View in: PubMed
  47. Morgan EF, Mason ZD, Chien KB, Pfeiffer AJ, Barnes GL, Einhorn TA, Gerstenfeld LC. Micro-computed tomography assessment of fracture healing: relationships among callus structure, composition, and mechanical function. Bone. 2009 Feb; 44(2):335-44. PMID: 19013264.
    View in: PubMed
  48. Wan C, Gilbert SR, Wang Y, Cao XM, Shen X, Ramaswamy G, Jacobsen KA, Alaql ZS, Gerstenfeld LC, Einhorn TA, Eberhardt AW, Deng L, Guldberg RE, Clemens TL. Role of hypoxia inducible factor-1 alpha pathway in bone regeneration. J Musculoskelet Neuronal Interact. 2008 Oct-Dec; 8(4):323-4. PMID: 19147958.
    View in: PubMed
  49. Morgan EF, Mason ZD, Bishop G, Davis AD, Wigner NA, Gerstenfeld LC, Einhorn TA. Combined effects of recombinant human BMP-7 (rhBMP-7) and parathyroid hormone (1-34) in metaphyseal bone healing. Bone. 2008 Dec; 43(6):1031-8. PMID: 18761113.
    View in: PubMed
  50. Jepsen KJ, Price C, Silkman LJ, Nicholls FH, Nasser P, Hu B, Hadi N, Alapatt M, Stapleton SN, Kakar S, Einhorn TA, Gerstenfeld LC. Genetic variation in the patterns of skeletal progenitor cell differentiation and progression during endochondral bone formation affects the rate of fracture healing. J Bone Miner Res. 2008 Aug; 23(8):1204-16. PMID: 18348700.
    View in: PubMed
  51. Jacobsen KA, Al-Aql ZS, Wan C, Fitch JL, Stapleton SN, Mason ZD, Cole RM, Gilbert SR, Clemens TL, Morgan EF, Einhorn TA, Gerstenfeld LC. Bone formation during distraction osteogenesis is dependent on both VEGFR1 and VEGFR2 signaling. J Bone Miner Res. 2008 May; 23(5):596-609. PMID: 18433297.
    View in: PubMed
  52. Hincke MT, Chien YC, Gerstenfeld LC, McKee MD. Colloidal-gold immunocytochemical localization of osteopontin in avian eggshell gland and eggshell. J Histochem Cytochem. 2008 May; 56(5):467-76. PMID: 18256019.
    View in: PubMed
  53. Barnes GL, Kakar S, Vora S, Morgan EF, Gerstenfeld LC, Einhorn TA. Stimulation of fracture-healing with systemic intermittent parathyroid hormone treatment. J Bone Joint Surg Am. 2008 Feb; 90 Suppl 1:120-7. PMID: 18292366.
    View in: PubMed
  54. Ai-Aql ZS, Alagl AS, Graves DT, Gerstenfeld LC, Einhorn TA. Molecular mechanisms controlling bone formation during fracture healing and distraction osteogenesis. J Dent Res. 2008 Feb; 87(2):107-18. PMID: 18218835.
    View in: PubMed
  55. Wan C, Gilbert SR, Wang Y, Cao X, Shen X, Ramaswamy G, Jacobsen KA, Alaql ZS, Eberhardt AW, Gerstenfeld LC, Einhorn TA, Deng L, Clemens TL. Activation of the hypoxia-inducible factor-1alpha pathway accelerates bone regeneration. Proc Natl Acad Sci U S A. 2008 Jan 15; 105(2):686-91. PMID: 18184809.
    View in: PubMed
  56. Kakar S, Einhorn TA, Vora S, Miara LJ, Hon G, Wigner NA, Toben D, Jacobsen KA, Al-Sebaei MO, Song M, Trackman PC, Morgan EF, Gerstenfeld LC, Barnes GL. Enhanced chondrogenesis and Wnt signaling in PTH-treated fractures. J Bone Miner Res. 2007 Dec; 22(12):1903-12. PMID: 17680724.
    View in: PubMed
  57. Betz VM, Betz OB, Glatt V, Gerstenfeld LC, Einhorn TA, Bouxsein ML, Vrahas MS, Evans CH. Healing of segmental bone defects by direct percutaneous gene delivery: effect of vector dose. Hum Gene Ther. 2007 Oct; 18(10):907-15. PMID: 17910523.
    View in: PubMed
  58. Tsiridis E, Morgan EF, Bancroft JM, Song M, Kain M, Gerstenfeld L, Einhorn TA, Bouxsein ML, Tornetta P. Effects of OP-1 and PTH in a new experimental model for the study of metaphyseal bone healing. J Orthop Res. 2007 Sep; 25(9):1193-203. PMID: 17506507.
    View in: PubMed
  59. Wang Y, Wan C, Deng L, Liu X, Cao X, Gilbert SR, Bouxsein ML, Faugere MC, Guldberg RE, Gerstenfeld LC, Haase VH, Johnson RS, Schipani E, Clemens TL. The hypoxia-inducible factor alpha pathway couples angiogenesis to osteogenesis during skeletal development. J Clin Invest. 2007 Jun; 117(6):1616-26. PMID: 17549257.
    View in: PubMed
  60. Betz OB, Betz VM, Nazarian A, Egermann M, Gerstenfeld LC, Einhorn TA, Vrahas MS, Bouxsein ML, Evans CH. Delayed administration of adenoviral BMP-2 vector improves the formation of bone in osseous defects. Gene Ther. 2007 Jul; 14(13):1039-44. PMID: 17460719.
    View in: PubMed
  61. Kayal RA, Tsatsas D, Bauer MA, Allen B, Al-Sebaei MO, Kakar S, Leone CW, Morgan EF, Gerstenfeld LC, Einhorn TA, Graves DT. Diminished bone formation during diabetic fracture healing is related to the premature resorption of cartilage associated with increased osteoclast activity. J Bone Miner Res. 2007 Apr; 22(4):560-8. PMID: 17243865.
    View in: PubMed
  62. Cho TJ, Kim JA, Chung CY, Yoo WJ, Gerstenfeld LC, Einhorn TA, Choi IH. Expression and role of interleukin-6 in distraction osteogenesis. Calcif Tissue Int. 2007 Mar; 80(3):192-200. PMID: 17340223.
    View in: PubMed
  63. Edgar CM, Chakravarthy V, Barnes G, Kakar S, Gerstenfeld LC, Einhorn TA. Autogenous regulation of a network of bone morphogenetic proteins (BMPs) mediates the osteogenic differentiation in murine marrow stromal cells. Bone. 2007 May; 40(5):1389-98. PMID: 17303481.
    View in: PubMed
  64. Gerstenfeld LC, Al-Ghawas M, Alkhiary YM, Cullinane DM, Krall EA, Fitch JL, Webb EG, Thiede MA, Einhorn TA. Selective and nonselective cyclooxygenase-2 inhibitors and experimental fracture-healing. Reversibility of effects after short-term treatment. J Bone Joint Surg Am. 2007 Jan; 89(1):114-25. PMID: 17200318.
    View in: PubMed
  65. Tsuji K, Bandyopadhyay A, Harfe BD, Cox K, Kakar S, Gerstenfeld L, Einhorn T, Tabin CJ, Rosen V. BMP2 activity, although dispensable for bone formation, is required for the initiation of fracture healing. Nat Genet. 2006 Dec; 38(12):1424-9. PMID: 17099713.
    View in: PubMed
  66. Alikhani M, Alikhani Z, Boyd C, MacLellan CM, Raptis M, Liu R, Pischon N, Trackman PC, Gerstenfeld L, Graves DT. Advanced glycation end products stimulate osteoblast apoptosis via the MAP kinase and cytosolic apoptotic pathways. Bone. 2007 Feb; 40(2):345-53. PMID: 17064973.
    View in: PubMed
  67. Gerstenfeld LC, Alkhiary YM, Krall EA, Nicholls FH, Stapleton SN, Fitch JL, Bauer M, Kayal R, Graves DT, Jepsen KJ, Einhorn TA. Three-dimensional reconstruction of fracture callus morphogenesis. J Histochem Cytochem. 2006 Nov; 54(11):1215-28. PMID: 16864894.
    View in: PubMed
  68. Boes M, Kain M, Kakar S, Nicholls F, Cullinane D, Gerstenfeld L, Einhorn TA, Tornetta P. Osteogenic effects of traumatic brain injury on experimental fracture-healing. J Bone Joint Surg Am. 2006 Apr; 88(4):738-43. PMID: 16595463.
    View in: PubMed
  69. Wang K, Vishwanath P, Eichler GS, Al-Sebaei MO, Edgar CM, Einhorn TA, Smith TF, Gerstenfeld LC. Analysis of fracture healing by large-scale transcriptional profile identified temporal relationships between metalloproteinase and ADAMTS mRNA expression. Matrix Biol. 2006 Jul; 25(5):271-81. PMID: 16584876.
    View in: PubMed
  70. Betz OB, Betz VM, Nazarian A, Pilapil CG, Vrahas MS, Bouxsein ML, Gerstenfeld LC, Einhorn TA, Evans CH. Direct percutaneous gene delivery to enhance healing of segmental bone defects. J Bone Joint Surg Am. 2006 Feb; 88(2):355-65. PMID: 16452748.
    View in: PubMed
  71. Gerstenfeld LC and Einhorn TA. Fracture Healing: The Biology of Bone Repair and Regeneration. 6th Edition of Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism. American Society of Bone and Mineral Research. 2006.
  72. Gerstenfeld LC, Wronski TJ, Hollinger JO, Einhorn TA. Application of histomorphometric methods to the study of bone repair. J Bone Miner Res. 2005 Oct; 20(10):1715-22. PMID: 16160729.
    View in: PubMed
  73. Alkhiary YM, Gerstenfeld LC, Krall E, Westmore M, Sato M, Mitlak BH, Einhorn TA. Enhancement of experimental fracture-healing by systemic administration of recombinant human parathyroid hormone (PTH 1-34). J Bone Joint Surg Am. 2005 Apr; 87(4):731-41. PMID: 15805200.
    View in: PubMed
  74. Lehmann W, Edgar CM, Wang K, Cho TJ, Barnes GL, Kakar S, Graves DT, Rueger JM, Gerstenfeld LC, Einhorn TA. Tumor necrosis factor alpha (TNF-alpha) coordinately regulates the expression of specific matrix metalloproteinases (MMPS) and angiogenic factors during fracture healing. Bone. 2005 Feb; 36(2):300-10. PMID: 15780956.
    View in: PubMed
  75. Javed A, Barnes GL, Pratap J, Antkowiak T, Gerstenfeld LC, van Wijnen AJ, Stein JL, Lian JB, Stein GS. Impaired intranuclear trafficking of Runx2 (AML3/CBFA1) transcription factors in breast cancer cells inhibits osteolysis in vivo. Proc Natl Acad Sci U S A. 2005 Feb 1; 102(5):1454-9. PMID: 15665096.
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  76. Jacobsen KA, Carvalho RS, Tsiridis E, Kakar S, Einhorn TA and Gerstenfeld LC. Bone formation during distraction osteogenesis requires VEGF receptor signaling. Proceedings of the Eighth International Conference on the Chemistry and Biology of Mineralized Tissues. ( eds. WJ Landis and J Sodek). University of Toronto Press. Toronto, Canada. 2005.
  77. Gerstenfeld LC, Edgar CM, Kakar S, Jacobsen K, Einhorn TA . Osteogenic Growth Factors and Cytokines and Their Role in Bone Repair. Engineering of Functional Skeletal Tissues, Volume 3 in Topics in Bone Biology (ed. by Mary C Farach-Carson, Antonios G Mikos and Felix Bronner). Springer-Verlag Ltd. London. 2005.
  78. Lehmann W, Schinke T, Schilling AF, Catalá-Lehnen P, Gebauer M, Pogoda P, Gerstenfeld LC, Rueger JM, Einhorn TA, Amling M. Absence of mouse pleiotrophin does not affect bone formation in vivo. Bone. 2004 Dec; 35(6):1247-55. PMID: 15589206.
    View in: PubMed
  79. Kim HK, Bian H, Randall T, Garces A, Gerstenfeld LC, Einhorn TA. Increased VEGF expression in the epiphyseal cartilage after ischemic necrosis of the capital femoral epiphysis. J Bone Miner Res. 2004 Dec; 19(12):2041-8. PMID: 15537448.
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  80. Barnes GL, Hebert KE, Kamal M, Javed A, Einhorn TA, Lian JB, Stein GS, Gerstenfeld LC. Fidelity of Runx2 activity in breast cancer cells is required for the generation of metastases-associated osteolytic disease. Cancer Res. 2004 Jul 1; 64(13):4506-13. PMID: 15231660.
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  81. Barroug A, Kuhn LT, Gerstenfeld LC, Glimcher MJ. Interactions of cisplatin with calcium phosphate nanoparticles: in vitro controlled adsorption and release. J Orthop Res. 2004 Jul; 22(4):703-8. PMID: 15183424.
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  82. Carvalho RS, Einhorn TA, Lehmann W, Edgar C, Al-Yamani A, Apazidis A, Pacicca D, Clemens TL, Gerstenfeld LC. The role of angiogenesis in a murine tibial model of distraction osteogenesis. Bone. 2004 May; 34(5):849-61. PMID: 15121017.
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  83. Gerstenfeld LC, Einhorn TA. COX inhibitors and their effects on bone healing. Expert Opin Drug Saf. 2004 Mar; 3(2):131-6. PMID: 15006719.
    View in: PubMed
  84. Kacena MA, Todd P, Gerstenfeld LC, Landis WJ. Experiments with osteoblasts cultured under hypergravity conditions. Microgravity Sci Technol. 2004; 15(1):28-34. PMID: 15773019.
    View in: PubMed
  85. Shea CM, Edgar CM, Einhorn TA, Gerstenfeld LC. BMP treatment of C3H10T1/2 mesenchymal stem cells induces both chondrogenesis and osteogenesis. J Cell Biochem. 2003 Dec 15; 90(6):1112-27. PMID: 14635186.
    View in: PubMed
  86. Gerstenfeld LC, Einhorn TA. Developmental aspects of fracture healing and the use of pharmacological agents to alter healing. J Musculoskelet Neuronal Interact. 2003 Dec; 3(4):297-303; discussion 320-1. PMID: 15758304.
    View in: PubMed
  87. Pacicca DM, Patel N, Lee C, Salisbury K, Lehmann W, Carvalho R, Gerstenfeld LC, Einhorn TA. Expression of angiogenic factors during distraction osteogenesis. Bone. 2003 Dec; 33(6):889-98. PMID: 14678848.
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  88. He H, Liu R, Desta T, Leone C, Gerstenfeld LC, Graves DT. Diabetes causes decreased osteoclastogenesis, reduced bone formation, and enhanced apoptosis of osteoblastic cells in bacteria stimulated bone loss. Endocrinology. 2004 Jan; 145(1):447-52. PMID: 14525917.
    View in: PubMed
  89. Cho TJ, Lehmann W, Edgar C, Sadeghi C, Hou A, Einhorn TA, Gerstenfeld LC. Tumor necrosis factor alpha activation of the apoptotic cascade in murine articular chondrocytes is associated with the induction of metalloproteinases and specific pro-resorptive factors. Arthritis Rheum. 2003 Oct; 48(10):2845-54. PMID: 14558090.
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  90. Gerstenfeld LC, Cho TJ, Kon T, Aizawa T, Tsay A, Fitch J, Barnes GL, Graves DT, Einhorn TA. Impaired fracture healing in the absence of TNF-alpha signaling: the role of TNF-alpha in endochondral cartilage resorption. J Bone Miner Res. 2003 Sep; 18(9):1584-92. PMID: 12968667.
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  91. Gerstenfeld LC, Thiede M, Seibert K, Mielke C, Phippard D, Svagr B, Cullinane D, Einhorn TA. Differential inhibition of fracture healing by non-selective and cyclooxygenase-2 selective non-steroidal anti-inflammatory drugs. J Orthop Res. 2003 Jul; 21(4):670-5. PMID: 12798067.
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  92. Cullinane DM, Salisbury KT, Alkhiary Y, Eisenberg S, Gerstenfeld L, Einhorn TA. Effects of the local mechanical environment on vertebrate tissue differentiation during repair: does repair recapitulate development? J Exp Biol. 2003 Jul; 206(Pt 14):2459-71. PMID: 12796461.
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  93. Barnes GL, Javed A, Waller SM, Kamal MH, Hebert KE, Hassan MQ, Bellahcene A, Van Wijnen AJ, Young MF, Lian JB, Stein GS, Gerstenfeld LC. Osteoblast-related transcription factors Runx2 (Cbfa1/AML3) and MSX2 mediate the expression of bone sialoprotein in human metastatic breast cancer cells. Cancer Res. 2003 May 15; 63(10):2631-7. PMID: 12750290.
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  94. Carvalho RS, Kostenuik PJ, Salih E, Bumann A, Gerstenfeld LC. Selective adhesion of osteoblastic cells to different integrin ligands induces osteopontin gene expression. Matrix Biol. 2003 May; 22(3):241-9. PMID: 12853034.
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  95. Gerstenfeld LC, Cullinane DM, Barnes GL, Graves DT, Einhorn TA. Fracture healing as a post-natal developmental process: molecular, spatial, and temporal aspects of its regulation. J Cell Biochem. 2003 Apr 1; 88(5):873-84. PMID: 12616527.
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  96. Gerstenfeld LC, Barnes GL, Shea CM, Einhorn TA. Osteogenic differentiation is selectively promoted by morphogenetic signals from chondrocytes and synergized by a nutrient rich growth environment. Connect Tissue Res. 2003; 44 Suppl 1:85-91. PMID: 12952179.
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  97. Lu H, Kraut D, Gerstenfeld LC, Graves DT. Diabetes interferes with the bone formation by affecting the expression of transcription factors that regulate osteoblast differentiation. Endocrinology. 2003 Jan; 144(1):346-52. PMID: 12488363.
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  98. Kinner B, Pacicca DM, Gerstenfeld LC, Lee CA, Einhorn TA, Spector M. Expression of smooth muscle actin in cells involved in distraction osteogenesis in a rat model. J Orthop Res. 2003 Jan; 21(1):20-7. PMID: 12507576.
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  99. Kacena MA, Todd P, Gerstenfeld LC, Landis WJ. Experiments with osteoblasts cultured under varying orientations with respect to the gravity vector. Cytotechnology. 2002 Sep; 39(3):147-54. PMID: 19003307.
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  100. Cullinane DM, Fredrick A, Eisenberg SR, Pacicca D, Elman MV, Lee C, Salisbury K, Gerstenfeld LC, Einhorn TA. Induction of a neoarthrosis by precisely controlled motion in an experimental mid-femoral defect. J Orthop Res. 2002 May; 20(3):579-86. PMID: 12038634.
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  101. Kinner B, Gerstenfeld LC, Einhorn TA, Spector M. Expression of smooth muscle actin in connective tissue cells participating in fracture healing in a murine model. Bone. 2002 May; 30(5):738-45. PMID: 11996913.
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  102. Cho TJ, Gerstenfeld LC, Einhorn TA. Differential temporal expression of members of the transforming growth factor beta superfamily during murine fracture healing. J Bone Miner Res. 2002 Mar; 17(3):513-20. PMID: 11874242.
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  103. Gerstenfeld LC, Cruceta J, Shea CM, Sampath K, Barnes GL, Einhorn TA. Chondrocytes provide morphogenic signals that selectively induce osteogenic differentiation of mesenchymal stem cells. J Bone Miner Res. 2002 Feb; 17(2):221-30. PMID: 11811552.
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  104. Barnes GL, Della Torre T, Sommer B, Young MF, Gerstenfeld LC. Transcriptional regulation restricting bone sialoprotein gene expression to both hypertrophic chondrocytes and osteoblasts. J Cell Biochem. 2002; 87(4):458-69. PMID: 12397605.
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  105. Carvalho RS, Bumann A, Schaffer JL, Gerstenfeld LC. Predominant integrin ligands expressed by osteoblasts show preferential regulation in response to both cell adhesion and mechanical perturbation. J Cell Biochem. 2002; 84(3):497-508. PMID: 11813255.
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  106. Aizawa T, Kon T, Einhorn TA, Gerstenfeld LC. Induction of apoptosis in chondrocytes by tumor necrosis factor-alpha. J Orthop Res. 2001 Sep; 19(5):785-96. PMID: 11562122.
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  107. Kon T, Cho TJ, Aizawa T, Yamazaki M, Nooh N, Graves D, Gerstenfeld LC, Einhorn TA. Expression of osteoprotegerin, receptor activator of NF-kappaB ligand (osteoprotegerin ligand) and related proinflammatory cytokines during fracture healing. J Bone Miner Res. 2001 Jun; 16(6):1004-14. PMID: 11393777.
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  108. Javed A, Barnes GL, Jasanya BO, Stein JL, Gerstenfeld L, Lian JB, Stein GS. runt homology domain transcription factors (Runx, Cbfa, and AML) mediate repression of the bone sialoprotein promoter: evidence for promoter context-dependent activity of Cbfa proteins. Mol Cell Biol. 2001 Apr; 21(8):2891-905. PMID: 11283267.
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  109. Harper J, Gerstenfeld LC, Klagsbrun M. Neuropilin-1 expression in osteogenic cells: down-regulation during differentiation of osteoblasts into osteocytes. J Cell Biochem. 2001; 81(1):82-92. PMID: 11180399.
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  111. Wang J, Yang R, Gerstenfeld LC, Glimcher MJ. Characterization of demineralized bone matrix-induced osteogenesis in rat calvarial bone defects: III. Gene and protein expression. Calcif Tissue Int. 2000 Oct; 67(4):314-20. PMID: 11000346.
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  113. Landis WJ, Hodgens KJ, Block D, Toma CD, Gerstenfeld LC. Spaceflight effects on cultured embryonic chick bone cells. J Bone Miner Res. 2000 Jun; 15(6):1099-112. PMID: 10841178.
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  114. Uzel MI, Shih SD, Gross H, Kessler E, Gerstenfeld LC, Trackman PC. Molecular events that contribute to lysyl oxidase enzyme activity and insoluble collagen accumulation in osteosarcoma cell clones. J Bone Miner Res. 2000 Jun; 15(6):1189-97. PMID: 10841188.
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  115. Nah HD, Pacifici M, Gerstenfeld LC, Adams SL, Kirsch T. Transient chondrogenic phase in the intramembranous pathway during normal skeletal development. J Bone Miner Res. 2000 Mar; 15(3):522-33. PMID: 10750567.
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  116. Isogai N, Landis WJ, Mori R, Gotoh Y, Gerstenfeld LC, Upton J, Vacanti JP. Experimental use of fibrin glue to induce site-directed osteogenesis from cultured periosteal cells. Plast Reconstr Surg. 2000 Mar; 105(3):953-63. PMID: 10724255.
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  117. Ranger AM, Gerstenfeld LC, Wang J, Kon T, Bae H, Gravallese EM, Glimcher MJ, Glimcher LH. The nuclear factor of activated T cells (NFAT) transcription factor NFATp (NFATc2) is a repressor of chondrogenesis. J Exp Med. 2000 Jan 3; 191(1):9-22. PMID: 10620601.
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  118. Mueller SM, Mizuno S, Gerstenfeld LC, Glowacki J. Medium perfusion enhances osteogenesis by murine osteosarcoma cells in three-dimensional collagen sponges. J Bone Miner Res. 1999 Dec; 14(12):2118-26. PMID: 10620071.
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  119. Barnes GL, Kostenuik PJ, Gerstenfeld LC, Einhorn TA. Growth factor regulation of fracture repair. J Bone Miner Res. 1999 Nov; 14(11):1805-15. PMID: 10571679.
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  120. Gerstenfeld LC. Osteopontin in skeletal tissue homeostasis: An emerging picture of the autocrine/paracrine functions of the extracellular matrix. J Bone Miner Res. 1999 Jun; 14(6):850-5. PMID: 10352092.
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  121. Isogai N, Landis W, Kim TH, Gerstenfeld LC, Upton J, Vacanti JP. Formation of phalanges and small joints by tissue-engineering. J Bone Joint Surg Am. 1999 Mar; 81(3):306-16. PMID: 10199268.
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  122. Gerstenfeld LC, Shih S,. George C, Mizuno S, and Glowacki J. Effect of over expression of bone sialoprotein or osteocalcin on osteosarcoma tissue growth and mineralization. The Chemistry and Biology of Mineralized Tissues (ed. M Goldberg, A Bosky, C Robinson). American Acad Orthop Surg. Chicago, IL. 1999.
  123. Pines M, Knopov V, Genina O, Hurwitz S, Faerman A, Gerstenfeld LC, Leach RM. Development of avian tibial dyschondroplasia: gene expression and protein synthesis. Calcif Tissue Int. 1998 Dec; 63(6):521-7. PMID: 9817948.
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  125. Carvalho RS, Schaffer JL, Gerstenfeld LC. Osteoblasts induce osteopontin expression in response to attachment on fibronectin: demonstration of a common role for integrin receptors in the signal transduction processes of cell attachment and mechanical stimulation. J Cell Biochem. 1998 Sep 1; 70(3):376-90. PMID: 9706875.
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  126. Meazzini MC, Toma CD, Schaffer JL, Gray ML, Gerstenfeld LC. Osteoblast cytoskeletal modulation in response to mechanical strain in vitro. J Orthop Res. 1998 Mar; 16(2):170-80. PMID: 9621891.
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  127. Gerstenfeld LC, von Deck M, Kelly C, Uskokovic M, Lian JB. 125(OH)2D3 Promotes differentiation of resting chondrocyte to hypertrophic cell in vitro: A model system for evaluating the potency of vitamin D Analogs. Vitamin D Molecular and Clinical Endocrinology ed. Norman a, Schaefer K, Grigoleit H; de Gruyter. W. Berlin. 1998.
  128. Toma CD, Schaffer JL, Meazzini MC, Zurakowski D, Nah HD, Gerstenfeld LC. Developmental restriction of embryonic calvarial cell populations as characterized by their in vitro potential for chondrogenic differentiation. J Bone Miner Res. 1997 Dec; 12(12):2024-39. PMID: 9421235.
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  129. Toma CD, Ashkar S, Gray ML, Schaffer JL, Gerstenfeld LC. Signal transduction of mechanical stimuli is dependent on microfilament integrity: identification of osteopontin as a mechanically induced gene in osteoblasts. J Bone Miner Res. 1997 Oct; 12(10):1626-36. PMID: 9333123.
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  130. Salih E, Ashkar S, Gerstenfeld LC, Glimcher MJ. Identification of the phosphorylated sites of metabolically 32P-labeled osteopontin from cultured chicken osteoblasts. J Biol Chem. 1997 May 23; 272(21):13966-73. PMID: 9153260.
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  131. Yang R, Gerstenfeld LC. Structural analysis and characterization of tissue and hormonal responsive expression of the avian bone sialoprotein (BSP) gene. J Cell Biochem. 1997 Jan; 64(1):77-93. PMID: 9015757.
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  132. Yang R, Gerstenfeld LC. Signal transduction pathways mediating parathyroid hormone stimulation of bone sialoprotein gene expression in osteoblasts. J Biol Chem. 1996 Nov 22; 271(47):29839-46. PMID: 8939923.
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  133. Salih E, Ashkar S, Gerstenfeld LC, Glimcher MJ. Protein kinases of cultured osteoblasts: selectivity for the extracellular matrix proteins of bone and their catalytic competence for osteopontin. J Bone Miner Res. 1996 Oct; 11(10):1461-73. PMID: 8889846.
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  134. Gerstenfeld LC, Zurakowski D, Schaffer JL, Nichols DP, Toma CD, Broess M, Bruder SP, Caplan AI. Variable hormone responsiveness of osteoblast populations isolated at different stages of embryogenesis and its relationship to the osteogenic lineage. Endocrinology. 1996 Sep; 137(9):3957-68. PMID: 8756572.
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  135. Gerstenfeld LC, Shapiro FD. Expression of bone-specific genes by hypertrophic chondrocytes: implication of the complex functions of the hypertrophic chondrocyte during endochondral bone development. J Cell Biochem. 1996 Jul; 62(1):1-9. PMID: 8836870.
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  136. Gerstenfeld LC, Uporova T, Schmidt J, Strauss PG, Shih SD, Huang LF, Gundberg C, Mizuno S, Glowacki J. Osteogenic potential of murine osteosarcoma cells: comparison of bone-specific gene expression in in vitro and in vivo conditions. Lab Invest. 1996 May; 74(5):895-906. PMID: 8642785.
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  137. Rey C, Kim HM, Gerstenfeld L, Glimcher MJ. Characterization of the apatite crystals of bone and their maturation in osteoblast cell culture: comparison with native bone crystals. Connect Tissue Res. 1996; 35(1-4):343-9. PMID: 9084674.
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  138. Salih E, Ashkar S, Zhou HY, Gerstenfeld L, Glimcher MJ. Protein kinases of cultured chicken osteoblasts that phosphorylate extracellular bone proteins. Connect Tissue Res. 1996; 35(1-4):207-13. PMID: 9084659.
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  139. Winnard RG, Gerstenfeld LC, Toma CD, Franceschi RT. Fibronectin gene expression, synthesis and accumulation during in vitro differentiation of chicken osteoblasts. J Bone Miner Res. 1995 Dec; 10(12):1969-77. PMID: 8619378.
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  140. Rey C, Kim HM, Gerstenfeld L, Glimcher MJ. Structural and chemical characteristics and maturation of the calcium-phosphate crystals formed during the calcification of the organic matrix synthesized by chicken osteoblasts in cell culture. J Bone Miner Res. 1995 Oct; 10(10):1577-88. PMID: 8686515.
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  141. Ashkar S, Schaffer JL, Salih E, Gerstenfeld LC, Glimcher MJ. Phosphorylation of osteopontin by Golgi kinases. Ann N Y Acad Sci. 1995 Apr 21; 760:296-8. PMID: 7785903.
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  142. Salih E, Ashkar S, Gerstenfeld LC, Glimcher MJ. Identification of the in vivo phosphorylated sites of secreted osteopontin from cultured chicken osteoblasts. Ann N Y Acad Sci. 1995 Apr 21; 760:357-60. PMID: 7785916.
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  143. Gerstenfeld LC, Uporova T, Ashkar S, Salih E, Gotoh Y, McKee MD, Nanci A, Glimcher MJ. Regulation of avian osteopontin pre- and posttranscriptional expression in skeletal tissues. Ann N Y Acad Sci. 1995 Apr 21; 760:67-82. PMID: 7785927.
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  144. Yang R, Gotoh Y, Moore MA, Rafidi K, Gerstenfeld LC. Characterization of an avian bone sialoprotein (BSP) cDNA: comparisons to mammalian BSP and identification of conserved structural domains. J Bone Miner Res. 1995 Apr; 10(4):632-40. PMID: 7610935.
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  145. Gotoh Y, Salih E, Glimcher MJ, Gerstenfeld LC. Characterization of the major non-collagenous proteins of chicken bone: identification of a novel 60 kDa non-collagenous phosphoprotein. Biochem Biophys Res Commun. 1995 Mar 17; 208(2):863-70. PMID: 7695644.
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  146. Broess M, Riva A, Gerstenfeld LC. Inhibitory effects of 1,25(OH)2 vitamin D3 on collagen type I, osteopontin, and osteocalcin gene expression in chicken osteoblasts. J Cell Biochem. 1995 Mar; 57(3):440-51. PMID: 7768979.
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  147. Neugebauer BM, Moore MA, Broess M, Gerstenfeld LC, Hauschka PV. Characterization of structural sequences in the chicken osteocalcin gene: expression of osteocalcin by maturing osteoblasts and by hypertrophic chondrocytes in vitro. J Bone Miner Res. 1995 Jan; 10(1):157-63. PMID: 7747623.
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  148. Schaffer JL, Rizen M, L'Italien GJ, Benbrahim A, Megerman J, Gerstenfeld LC, Gray ML. Device for the application of a dynamic biaxially uniform and isotropic strain to a flexible cell culture membrane. J Orthop Res. 1994 Sep; 12(5):709-19. PMID: 7931788.
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  149. Gerstenfeld LC, Feng M, Gotoh Y, Glimcher MJ. Selective extractability of noncollagenous proteins from chicken bone. Calcif Tissue Int. 1994 Sep; 55(3):230-5. PMID: 7987738.
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  150. Rafidi K, Simkina I, Johnson E, Moore MA, Gerstenfeld LC. Characterization of the chicken osteopontin-encoding gene. Gene. 1994 Mar 25; 140(2):163-9. PMID: 8144023.
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  151. Davidovitch M and Gerstenfeld LC. Differential Effects of PTH on cAMP and Collagen I-RNA Production by Chick Osteoblasts. The Biological Mechanisms of Tooth Eruption, Resorption and Replacement by Implants (ed. Ze'ev Davidovitch). Harvard Society for the Advancement of Orthodontics, EBSCO, Media. Birmingham, AL. 1994; pg. 239-252.
  152. Schaffer JL, Toma CD, Meazzini MC, Gray ML and Gerstenfeld LC. Mechanical stimulation of osteopontin gene expression and its relationship to microfilament structure. The Biological Mechanisms of Tooth Movement and Cranial Facial Adaptation (ed Ze'ev Davidovitch and Louis Norton ). Harvard Society for the Advancement of Orthodontics, EBSCO, Media. Birmingham, AL. 1994; pg. 113-121.
  153. Gerstenfeld LC, Riva A, Hodgens K, Eyre DR, Landis WJ. Post-translational control of collagen fibrillogenesis in mineralizing cultures of chick osteoblasts. J Bone Miner Res. 1993 Sep; 8(9):1031-43. PMID: 8237472.
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  154. Lian JB, McKee MD, Todd AM, Gerstenfeld LC. Induction of bone-related proteins, osteocalcin and osteopontin, and their matrix ultrastructural localization with development of chondrocyte hypertrophy in vitro. J Cell Biochem. 1993 Jun; 52(2):206-19. PMID: 8366137.
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  155. Gerstenfeld LC, Broess M, Bruder S, Caplan A, Landis WJ. Regulation of osteoblast extracellular matrix formation: posttranslational regulation of extracellular matrix deposition and relationship between embryonic development and hormonal response. Chemistry and Biology of Mineralized Tissues (ed. H. Slavkin and P. Price). Elsevier. Amsterdam, Netherlands. 1992; pg. 287-295.
  156. Tassinari MS, Gerstenfeld LC, Stein GS, Lian JB. Effect of caffeine on parameters of osteoblast growth and differentiation of a mineralized extracellular matrix in vitro. J Bone Miner Res. 1991 Oct; 6(10):1029-36. PMID: 1796750.
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  164. Aronow MA, Gerstenfeld LC, Owen TA, Tassinari MS, Stein GS, Lian JB. Factors that promote progressive development of the osteoblast phenotype in cultured fetal rat calvaria cells. J Cell Physiol. 1990 May; 143(2):213-21. PMID: 2332447.
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  167. Gerstenfeld LC, Kelly CM, Von Deck M, Lian JB. Comparative morphological and biochemical analysis of hypertrophic, non-hypertrophic and 1,25(OH)2D3 treated non-hypertrophic chondrocytes. Connect Tissue Res. 1990; 24(1):29-39. PMID: 1692522.
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  176. Finer MH, Aho S, Gerstenfeld LC, Boedtker H, Doty P. Unusual DNA sequences located within the promoter region and the first intron of the chicken pro-alpha 1(I) collagen gene. J Biol Chem. 1987 Sep 25; 262(27):13323-32. PMID: 2820966.
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  178. Mackowiak S, Gerstenfeld L, Hauschka PV, Lian JB. Cell-free translation of the vitamin K-dependent bone protein osteocalcin. Biochem Biophys Res Commun. 1985 Oct 15; 132(1):240-4. PMID: 3877507.
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  179. Gerstenfeld LC, Finer MH, Boedtker H. Altered beta-actin gene expression in phorbol myristate acetate-treated chondrocytes and fibroblasts. Mol Cell Biol. 1985 Jun; 5(6):1425-33. PMID: 4033660.
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  181. Gerstenfeld LC, Crawford DR, Boedtker H, Doty P. Expression of type I and III collagen genes during differentiation of embryonic chicken myoblasts in culture. Mol Cell Biol. 1984 Aug; 4(8):1483-92. PMID: 6548546.
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  182. Gerstenfeld L, Beldekas JC, Sonenshein GE, Franzblau C. Processing of procollagen types III and I in cultured bovine smooth muscle cells. J Biol Chem. 1984 Jul 25; 259(14):9158-62. PMID: 6746644.
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  183. Gerstenfeld L, Beldekas JC, Franzblau C, Sonenshein GE. Cell-free translation of calf type III collagen. Effect of magnesium on ribosome movement during elongation. J Biol Chem. 1983 Oct 10; 258(19):12058-63. PMID: 6619153.
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