Mark Grinstaff | Profiles RNS

Mark Grinstaff, PhD

William Fairfield Warren Distinguished Professor

Boston University

PhD, University of Illinois
AB, Occidental College

Websites

	Grinstaff Group
	Biomedical Engineering Faculty
	Chemistry Faculty
	Public Relations - BU Experts
	BU Nanotechnology Innovation Center (BUnano)
	Research Gate
	Google Scholar
	LinkedIn
	Twitter
	Wikipedia

ORCID : 0000-0002-5453-3668

Mark W. Grinstaff is a Distinguished Professor of Translational Research, Biomedical Engineering, Chemistry, Materials Science and Engineering, and Medicine as well as the Director of the NIH T32 Program in Biomaterials and the Director of the Nanotechnology Innovation Center at Boston University.

Mark received his Ph.D. from the University of Illinois under the mentorship of Professor Kenneth S. Suslick and was an NIH postdoctoral fellow at the California Institute of Technology with Professor Harry B. Gray. Mark's awards include the ACS Nobel Laureate Signature Award, NSF Career Award, Pew Scholar in the Biomedical Sciences, Camille Dreyfus Teacher- Scholar, Alfred P. Sloan Research Fellowship, the Edward M. Kennedy Award for Health Care Innovation, and a Founding Fellow of the National Academy of Inventors. He is an author or co-author on more than 225 peer-reviewed manuscripts, given more than 300 oral presentations, and an inventor or co- inventor on more than 200 issued patents or pending applications. His students and fellows have given more than 125 oral presentations and 350 posters at national and international meetings.

Mark's current research activities involve the synthesis of new macromolecules and biomaterials, self-assembly chemistry, imaging contrast agents, drug delivery, and wound repair. His group pursues highly interdisciplinary research in the areas of biomedical engineering and macromolecular chemistry. The major goal in these research projects is to elucidate the underlying fundamental chemistry and engineering principles and to use that insight to direct our creative and scientific efforts. In one of their current research projects, they are designing, synthesizing, and characterizing novel dendrimers, termed “biodendrimers,” for tissue engineering and biotechnological applications. Currently, they are evaluating these novel biomaterials for the repair of corneal lacerations, for the delivery of anti-cancer drugs, for the delivery of DNA, and as temporary biodegradable scaffolds for cartilage repair. In a second project, they are creating novel polymeric coatings termed “interfacial biomaterials” that control biology on plastic, metal, and ceramic surfaces. In a third project, they are designing new polymeric films and nanoparticles loaded with anticancer drugs for the prevention of recurrent cancer after surgical resection.

Mark is a co-founder of several companies that are commercializing his ideas, and he has several products being sold and used in the clinic.

Professor
Boston University College of Arts and Sciences
Chemistry

Director
Boston University
Nanotechnology Innovation Center (BUnano)

Professor
Boston University College of Engineering
Biomedical Engineering

Professor
Boston University Chobanian & Avedisian School of Medicine
Medicine
Pulmonary, Allergy, Sleep & Critical Care Medicine

Associate Director for Engineering & Sciences
Boston University
BU-BMC Cancer Center

Member
Boston University
Pulmonary Center

Member
Boston University
Evans Center for Interdisciplinary Biomedical Research

Member
Boston University
Genome Science Institute

Graduate Faculty (Primary Mentor of Grad Students)
Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences

BU Research
NIH RePORTER Research

Modified saRNA Encoded BiTEs for Lung Cancer
01/01/2025 - 12/31/2029 (PI)
NIH/National Cancer Institute
1R01CA296810-01

A Bio-orthogonal Targeting System for Precision Drug Delivery to Vascular Endothelium in Transplanted Organs
09/30/2024 - 09/29/2029 (Key Person / Mentor)
NIH/National Heart, Lung, and Blood Institute
1F30HL176145-01

Lysosomal Regeneration (LysoGen) and Rescue as a Treatment for Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
09/20/2024 - 07/31/2029 (PI)
NIH/National Diabetes & Digestive & Kidney Diseases
1R01DK141923-01

A Relaxin-loaded Hydrogel for the Treatment of Hypertrophic Scars
07/01/2024 - 06/30/2029 (Multi-PI)
PI: Mark Grinstaff, PhD
NIH/National Institute of Arthritis & Musculoskeletal & Skin Diseases
1R01AR083161-01A1

Trailblazer: Solving the Grand Self-Amplifying RNA (saRNA) Challenge
09/01/2024 - 08/31/2027 (PI)
National Science Foundation
EFMA-2421692

Translational Research in Biomaterials
09/01/2022 - 08/31/2027 (Multi-PI)
PI: Mark Grinstaff, PhD
NIH/National Institute of Biomedical Imaging & Bioengineering
5T32EB006359-15

Supratherapeutic PTX Buttresses Reduce Locoregional Recurrence Rates Following Surgery for Soft Tissue Sarcomas
08/01/2022 - 07/31/2027 (Multi-PI)
PI: Mark Grinstaff, PhD
The Brigham and Women's Hospital, Inc. NIH NCI
5R01CA272637-03

The Conundrum of Absentee Receptors: Efficacy Potentiation Through Drug-Receptor Modulation
09/21/2022 - 06/30/2027 (PI)
NIH/National Institute of Arthritis & Musculoskeletal & Skin Diseases
5R01AR081264-03

Arthroscopic Raman Monitoring of Cartilage Content for PTOA Diagnosis and Chondroregenerative Treatment Response
08/02/2022 - 05/31/2027 (Co-Investigator)
NIH/National Institute of Arthritis & Musculoskeletal & Skin Diseases
5R01AR081393-03

Sustained Release Relaxin-2 for the Treatment of Frozen Shoulder
08/01/2022 - 05/31/2027 (PI)
NIH/National Institute of Arthritis & Musculoskeletal & Skin Diseases
5R01AR079489-03

Showing 10 of 66 results. Show All Results

Title

Yr	Title	Project-Sub Proj
2025	Modified saRNA Encoded BiTEs for Lung Cancer	1R01CA296810-01
2024	Lysosomal Regeneration (LysoGen) and Rescue as a Treatment for Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)	1R01DK141923-01
2024	A Relaxin-loaded Hydrogel for the Treatment of Hypertrophic Scars	1R01AR083161-01A1
2024	The Conundrum of Absentee Receptors: Efficacy Potentiation Through Drug-Receptor Modulation	5R01AR081264-03
2024	Biodegradable, Biocompatible Pressure Sensitive Adhesives	5R01HL159644-03
2024	Supratherapeutic PTX Buttresses Reduce Locoregional Recurrence Rates Following Surgery for Soft Tissue Sarcomas	5R01CA272637-03
2024	Sustained Release Relaxin-2 for the Treatment of Frozen Shoulder	5R01AR079489-03
2024	Sulfated Poly-Amido-Saccharide (sulPAS) Biomaterials as Anticoagulants	5R01HL164650-03
2024	Precise tumor targeting with logic CAR circuits	5U01CA265713-04
2024	Translational Research in Biomaterials	5T32EB006359-15

Showing 10 of 113 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Paakkari P, Inkinen SI, Mohammadi A, Nieminen MT, Joenathan A, Grinstaff MW, Töyräs J, Mäkelä JTA, Honkanen JTJ. Photon-counting in dual-contrast-enhanced computed tomography: a proof-of-concept quantitative biomechanical assessment of articular cartilage. Sci Rep. 2024 Dec 02; 14(1):29956. PMID: 39622931; PMCID: PMC11612382; DOI: 10.1038/s41598-024-78237-1;

Xie L, Wu Q, Li K, Khan MAS, Zhang A, Sinha B, Li S, Chang SL, Brody DL, Grinstaff MW, Zhou S, Alterovitz G, Liu P, Wang X. Tryptophan Metabolism in Alzheimer's Disease with the Involvement of Microglia and Astrocyte Crosstalk and Gut-Brain Axis. Aging Dis. 2024 Oct 01; 15(5):2168-2190.View Related Profiles.

Sinha, Bharati
Grinstaff, Mark

PMID: 38916729; PMCID: PMC11346405; DOI: 10.14336/AD.2024.0134;

El-Arid S, Lenihan JM, Beeler AB, Grinstaff MW. Truxinates and truxillates: building blocks for architecturally complex polymers and advanced materials. Polym Chem. 2024 Oct 08; 15(39):3935-3953.View Related Profiles.

Beeler, Aaron
Grinstaff, Mark

PMID: 39310896; PMCID: PMC11414186; DOI: 10.1039/d4py00548a;

Sabatelle RC, Geller A, Li S, Van Heest A, Sachdeva UM, Bressler E, Korunes-Miller J, Tfayli B, Tal-Mason A, Kharroubi H, Colson YL, Grinstaff MW. Synthesis of Amphiphilic Amino Poly-Amido-Saccharide and Poly(lactic) Acid Block Copolymers and Fabrication of Paclitaxel-Loaded Mucoadhesive Nanoparticles. Bioconjug Chem. 2024 Sep 18; 35(9):1429-1440. PMID: 39159059

Martin A, Zhang S, Williamson A, Tingley B, Pickus M, Zurakowski D, Nia HT, Shirihai O, Han X, Grinstaff MW. Dispersion indices for universal quantification of fluorescently-labelled subcellular structure spatial distributions. bioRxiv. 2024 Aug 19.View Related Profiles.

Nia, Hadi
Grinstaff, Mark

PMID: 39229224; PMCID: PMC11370428; DOI: 10.1101/2024.08.18.608451;

Tuppurainen J, Paakkari P, Jäntti J, Nissinen MT, Fugazzola MC, van Weeren R, Ylisiurua S, Nieminen MT, Kröger H, Snyder BD, Joenathan A, Grinstaff MW, Matikka H, Korhonen RK, Mäkelä JTA. Revealing Detailed Cartilage Function Through Nanoparticle Diffusion Imaging: A Computed Tomography & Finite Element Study. Ann Biomed Eng. 2024 Sep; 52(9):2584-2595. PMID: 39012563; PMCID: PMC11329549; DOI: 10.1007/s10439-024-03552-7;

McGee JE, Kirsch JR, Kenney D, Cerbo F, Chavez EC, Shih TY, Douam F, Wong WW, Grinstaff MW. Complete substitution with modified nucleotides in self-amplifying RNA suppresses the interferon response and increases potency. Nat Biotechnol. 2024 Jul 08.View Related Profiles.

Douam, Florian
Grinstaff, Mark

PMID: 38977924

Sabatelle RC, Colson YL, Sachdeva U, Grinstaff MW. Drug Delivery Opportunities in Esophageal Cancer: Current Treatments and Future Prospects. Mol Pharm. 2024 Jul 01; 21(7):3103-3120. PMID: 38888089; PMCID: PMC11331583; DOI: 10.1021/acs.molpharmaceut.4c00246;

Zhang T, Li K, Cheung YH, Grinstaff MW, Liu P. Photo-reduction facilitated stachydrine oxidative N-demethylation reaction: A case study of Rieske non-heme iron oxygenase Stc2 from Sinorhizobium meliloti. Methods Enzymol. 2024; 703:263-297. PMID: 39260999

DeMoya CD, Joenathan A, Lawson TB, Felson DT, Schaer TP, Bais M, Albro MB, Mäkelä J, Snyder BD, Grinstaff MW. Advances in viscosupplementation and tribosupplementation for early-stage osteoarthritis therapy. Nat Rev Rheumatol. 2024 Jul; 20(7):432-451.View Related Profiles.

Felson, David
Grinstaff, Mark

PMID: 38858605; PMCID: PMC11348290; DOI: 10.1038/s41584-024-01125-5;

Showing 10 of 409 results. Show More

Lo CH, O'Connor LM, Loi GWZ, Saipuljumri EN, Indajang J, Lopes KM, Shirihai OS, Grinstaff MW, Zeng J. Acidic Nanoparticles Restore Lysosomal Acidification and Rescue Metabolic Dysfunction in Pancreatic ß-Cells under Lipotoxic Conditions. ACS Nano. 2024 Jun 18; 18(24):15452-15467. PMID: 38830624; PMCID: PMC11192035; DOI: 10.1021/acsnano.3c09206;

Nelson BB, Mäkelä JTA, Lawson TB, Patwa AN, Snyder BD, McIlwraith CW, Grinstaff MW, Seabaugh KA, Barrett MF, Goodrich LR, Kawcak CE. Longitudinal in vivo cationic contrast-enhanced computed tomography classifies equine articular cartilage injury and repair. J Orthop Res. 2024 Oct; 42(10):2264-2276. PMID: 38715519

Nourmahnad A, Javad Shariyate M, Khak M, Grinstaff MW, Nazarian A, Rodriguez EK. Relaxin as a treatment for musculoskeletal fibrosis: What we know and future directions. Biochem Pharmacol. 2024 Jul; 225:116273. PMID: 38729446; PMCID: PMC11179965; DOI: 10.1016/j.bcp.2024.116273;

Adams SC, Nambiar AK, Bressler EM, Raut CP, Colson YL, Wong WW, Grinstaff MW. Immunotherapies for locally aggressive cancers. Adv Drug Deliv Rev. 2024 Jul; 210:115331. PMID: 38729264; PMCID: PMC11228555; DOI: 10.1016/j.addr.2024.115331;

El-Arid S, Lenihan JM, Jacobsen A, Beeler AB, Grinstaff MW. Accessing Cyclobutane Polymers: Overcoming Synthetic Challenges via Efficient Continuous Flow [2 + 2] Photopolymerization. ACS Macro Lett. 2024 May 21; 13(5):607-613.View Related Profiles.

Beeler, Aaron
Grinstaff, Mark

PMID: 38695337; PMCID: PMC11414449; DOI: 10.1021/acsmacrolett.4c00083;

Sankar K, Kuzmanovic U, Schaus SE, Galagan JE, Grinstaff MW. Strategy, Design, and Fabrication of Electrochemical Biosensors: A Tutorial. ACS Sens. 2024 May 24; 9(5):2254-2274.View Related Profiles.

Galagan, James
Grinstaff, Mark
Schaus, Scott

PMID: 38636962

Stewart HL, Gilbert D, Stefanovski D, Garman Z, Albro MB, Bais M, Grinstaff MW, Snyder BD, Schaer TP. A missed opportunity: A scoping review of the effect of sex and age on osteoarthritis using large animal models. Osteoarthritis Cartilage. 2024 May; 32(5):501-513.View Related Profiles.

Bais, Manish
Grinstaff, Mark

PMID: 38408635; PMCID: PMC11534084; DOI: 10.1016/j.joca.2024.02.009;

Sabatelle RC, Chu NQ, Blessing W, Kharroubi H, Bressler E, Tsai L, Shih A, Grinstaff MW, Colson Y. Decreased Lung Metastasis in Triple Negative Breast Cancer Following Locally Delivered Supratherapeutic Paclitaxel-Loaded Polyglycerol Carbonate Nanoparticle Therapy. Biomacromolecules. 2024 Mar 11; 25(3):1800-1809. PMID: 38380618; PMCID: PMC11331584; DOI: 10.1021/acs.biomac.3c01258;

Jäntti J, Joenathan A, Fugazzola M, Tuppurainen J, Honkanen JTJ, Töyräs J, van Weeren R, Snyder BD, Grinstaff MW, Matikka H, Mäkelä JTA. Cationic tantalum oxide nanoparticle contrast agent for micro computed tomography reveals articular cartilage proteoglycan distribution and collagen architecture alterations. Osteoarthritis Cartilage. 2024 Mar; 32(3):299-309. PMID: 38061579

Cooper BG, DeMoya CD, Sikes KJ, Frisbie DD, Phillips N, Nelson BB, McIlwraith CW, Kawcak CE, Goodrich LR, Snyder BD, Grinstaff MW. A polymer network architecture provides superior cushioning and lubrication of soft tissue compared to a linear architecture. Biomater Sci. 2023 Nov 07; 11(22):7339-7345.View Related Profiles.

Cooper, Benjamin
Grinstaff, Mark

PMID: 37847186; PMCID: PMC11500756; DOI: 10.1039/d3bm00753g;

Grazon C, Garanger E, Lalanne P, Ibarboure E, Galagan JE, Grinstaff MW, Lecommandoux S. Transcription-Factor-Induced Aggregation of Biomimetic Oligonucleotide-b-Protein Micelles. Biomacromolecules. 2023 Nov 13; 24(11):5027-5034.View Related Profiles.

Galagan, James
Grinstaff, Mark

PMID: 37877162

Mahvi DA, Korunes-Miller J, Bordeianu C, Chu NQ, Geller AD, Sabatelle R, Berry S, Hung YP, Colson YL, Grinstaff MW, Raut CP. High dose, dual-release polymeric films for extended surgical bed paclitaxel delivery. J Control Release. 2023 Nov; 363:682-691. PMID: 37776906; PMCID: PMC10990290; DOI: 10.1016/j.jconrel.2023.09.048;

McGee JE, Kirsch JR, Kenney D, Chavez E, Shih TY, Douam F, Wong WW, Grinstaff MW. Complete substitution with modified nucleotides suppresses the early interferon response and increases the potency of self-amplifying RNA. bioRxiv. 2023 Sep 17.View Related Profiles.

Douam, Florian
Grinstaff, Mark

PMID: 37745375; PMCID: PMC10516017; DOI: 10.1101/2023.09.15.557994;

Orava H, Paakkari P, Jäntti J, Honkanen MKM, Honkanen JTJ, Virén T, Joenathan A, Tanska P, Korhonen RK, Grinstaff MW, Töyräs J, Mäkelä JTA. Triple contrast computed tomography reveals site-specific biomechanical differences in the human knee joint-A proof of concept study. J Orthop Res. 2024 Feb; 42(2):415-424. PMID: 37593815

Zhang S, Grifno G, Passaro R, Regan K, Zheng S, Hadzipasic M, Banerji R, O'Connor L, Chu V, Kim SY, Yang J, Shi L, Karrobi K, Roblyer D, Grinstaff MW, Nia HT. Intravital measurements of solid stresses in tumours reveal length-scale and microenvironmentally dependent force transmission. Nat Biomed Eng. 2023 Nov; 7(11):1473-1492.View Related Profiles.

Roblyer, Darren
Nia, Hadi
Grinstaff, Mark

PMID: 37640900; PMCID: PMC10836235; DOI: 10.1038/s41551-023-01080-8;

Bressler EM, Adams S, Liu R, Colson YL, Wong WW, Grinstaff MW. Boolean logic in synthetic biology and biomaterials: Towards living materials in mammalian cell therapeutics. Clin Transl Med. 2023 Jul; 13(7):e1244. PMID: 37386762; PMCID: PMC10310979; DOI: 10.1002/ctm2.1244;

Fitzgerald DM, Zhang H, Bordeianu C, Colson YL, Grinstaff MW. Synthesis of Polyethylene Glycol-Poly(glycerol carbonate) Block Copolymeric Micelles as Surfactant-Free Drug Delivery Systems. ACS Macro Lett. 2023 Jul 18; 12(7):974-979. PMID: 37390500; PMCID: PMC11331582; DOI: 10.1021/acsmacrolett.3c00275;

Zhang S, Regan K, Najera J, Grinstaff MW, Datta M, Nia HT. The peritumor microenvironment: physics and immunity. Trends Cancer. 2023 Aug; 9(8):609-623.View Related Profiles.

Nia, Hadi
Grinstaff, Mark

PMID: 37156677; PMCID: PMC10523902; DOI: 10.1016/j.trecan.2023.04.004;

Zeng J, Acin-Perez R, Assali EA, Martin A, Brownstein AJ, Petcherski A, Fernández-Del-Rio L, Xiao R, Lo CH, Shum M, Liesa M, Han X, Shirihai OS, Grinstaff MW. Restoration of lysosomal acidification rescues autophagy and metabolic dysfunction in non-alcoholic fatty liver disease. Nat Commun. 2023 May 04; 14(1):2573. PMID: 37142604; PMCID: PMC10160018; DOI: 10.1038/s41467-023-38165-6;

Fitzgerald DM, Colson YL, Grinstaff MW. Synthetic Pressure Sensitive Adhesives for Biomedical Applications. Prog Polym Sci. 2023 Jul; 142. PMID: 37273788; PMCID: PMC10237363; DOI: 10.1016/j.progpolymsci.2023.101692;

Hu X, Grinstaff MW. Advances in Hydrogel Adhesives for Gastrointestinal Wound Closure and Repair. Gels. 2023 Mar 31; 9(4). PMID: 37102894; PMCID: PMC10138019; DOI: 10.3390/gels9040282;

Altinbasak I, Kocak S, Colby AH, Alp Y, Sanyal R, Grinstaff MW, Sanyal A. pH-Responsive nanofiber buttresses as local drug delivery devices. Biomater Sci. 2023 Jan 31; 11(3):813-821.View Related Profiles.

Colby, Aaron
Grinstaff, Mark

PMID: 36408890; PMCID: PMC9930888; DOI: 10.1039/d2bm01199a;

Colby AH, Kirsch J, Patwa AN, Liu R, Hollister B, McCulloch W, Burdette JE, Pearce CJ, Oberliels NH, Colson YL, Liu K, Grinstaff MW. Radiolabeled Biodistribution of Expansile Nanoparticles: Intraperitoneal Administration Results in Tumor Specific Accumulation. ACS Nano. 2023 Feb 14; 17(3):2212-2221.View Related Profiles.

Colby, Aaron
Grinstaff, Mark

PMID: 36701244; PMCID: PMC9933882; DOI: 10.1021/acsnano.2c08451;

Cook KA, Martinez-Lozano E, Sheridan R, Rodriguez EK, Nazarian A, Grinstaff MW. Hydrogels for the management of second-degree burns: currently available options and future promise. Burns Trauma. 2022; 10:tkac047. PMID: 36518878; PMCID: PMC9733594; DOI: 10.1093/burnst/tkac047;

Bressler EM, Chu NQ, Sabatelle RC, Mahvi DA, Korunes-Miller JT, Nagashima F, Ichinose F, Liu R, Grinstaff MW, Colson YL, Raut CP. Doxorubicin-Loaded Polymeric Meshes Prevent Local Recurrence after Sarcoma Resection While Avoiding Cardiotoxicity. Cancer Res. 2022 Dec 02; 82(23):4474-4484. PMID: 36169924; PMCID: PMC9948765; DOI: 10.1158/0008-5472.CAN-22-0734;

Fitzgerald DM, Colson YL, Grinstaff MW. Advancing pressure-sensitive adhesives for internal wound closure. Nat Rev Mater. 2023 Jan; 8(1):3-5. PMID: 37206300; PMCID: PMC10193518; DOI: 10.1038/s41578-022-00516-y;

Hu WY, Li K, Weitz A, Wen A, Kim H, Murray JC, Cheng R, Chen B, Naowarojna N, Grinstaff MW, Elliott SJ, Chen JS, Liu P. Light-driven Oxidative Demethylation Reaction Catalyzed by a Rieske-type Non-heme Iron Enzyme Stc2. ACS Catal. 2022 Dec 02; 12(23):14559-14570.View Related Profiles.

Grinstaff, Mark
Elliott, Sean

PMID: 37168530; PMCID: PMC10168674; DOI: 10.1021/acscatal.2c04232;

Tsai LL, Fitzgerald DM, Liu R, Korunes-Miller JT, Neal E, Hung YP, Bilton S, Hata A, Grinstaff MW, Colson YL. Porous Paclitaxel Mesh Reduces Local Recurrence in Patient-Derived Xenograft Resection Model. Ann Thorac Surg. 2023 Jul; 116(1):181-188. PMID: 36376135; PMCID: PMC10172394; DOI: 10.1016/j.athoracsur.2022.09.048;

Blessing WA, Digesu CS, Liu R, Mahvi DA, Tal-Mason A, Kumar A, Hachey KJ, Colby AH, Korunes-Miller JT, Agar N, Regan MS, Shih A, Raut CP, Grinstaff MW, Colson YL. Sustained Supratherapeutic Paclitaxel Delivery Enhances Irreversible Sarcoma Cell Death. Mol Cancer Ther. 2022 Nov 03; 21(11):1663-1673.View Related Profiles.

Colby, Aaron
Digesu, Christopher
Grinstaff, Mark

PMID: 36031342; PMCID: PMC9633561; DOI: 10.1158/1535-7163.MCT-21-0750;

Kirsch JR, Williamson AK, Yeritsyan D, Blessing WA, Momenzadeh K, Leach TR, Williamson PM, Korunes-Miller JT, DeAngelis JP, Zurakowski D, Nazarian RM, Rodriguez EK, Nazarian A, Grinstaff MW. Minimally invasive, sustained-release relaxin-2 microparticles reverse arthrofibrosis. Sci Transl Med. 2022 Oct 12; 14(666):eabo3357. PMID: 36223449; PMCID: PMC9948766; DOI: 10.1126/scitranslmed.abo3357;

Sockett KA, Loffredo M, Korunes-Miller J, Varghese M, Grinstaff MW. Synthesis and characterization of carbohydrate-based biosurfactant mimetics. Carbohydr Res. 2022 Dec; 522:108697. PMID: 36272207; PMCID: PMC10211081; DOI: 10.1016/j.carres.2022.108697;

Varghese M, Grinstaff MW. Beyond nylon 6: polyamides via ring opening polymerization of designer lactam monomers for biomedical applications. Chem Soc Rev. 2022 Oct 03; 51(19):8258-8275. PMID: 36047318; PMCID: PMC9856205; DOI: 10.1039/d1cs00930c;

Scott KM, Cohen DJ, Nielson DW, Kim G, Olson LC, McClure MJ, Grinstaff MW, Boyan BD, Schwartz Z. Prophylactic administration of miR-451 inhibitor decreases osteoarthritis severity in rats. Sci Rep. 2022 Sep 27; 12(1):16068. PMID: 36167718; PMCID: PMC9513290; DOI: 10.1038/s41598-022-20415-0;

Xiao R, Zeng J, Bressler EM, Lu W, Grinstaff MW. Synthesis of bioactive (1?6)-ß-glucose branched poly-amido-saccharides that stimulate and induce M1 polarization in macrophages. Nat Commun. 2022 Aug 09; 13(1):4661. PMID: 35945224; PMCID: PMC9363418; DOI: 10.1038/s41467-022-32346-5;

Al Subeh ZY, Poschel DB, Redd PS, Klement JD, Merting AD, Yang D, Mehta M, Shi H, Colson YL, Oberlies NH, Pearce CJ, Colby AH, Grinstaff MW, Liu K. Lipid Nanoparticle Delivery of Fas Plasmid Restores Fas Expression to Suppress Melanoma Growth In Vivo. ACS Nano. 2022 Aug 23; 16(8):12695-12710.View Related Profiles.

Colby, Aaron
Grinstaff, Mark

PMID: 35939651; PMCID: PMC9721370; DOI: 10.1021/acsnano.2c04420;

Martinez-Lozano E, Beeram I, Yeritsyan D, Grinstaff MW, Snyder BD, Nazarian A, Rodriguez EK. Management of arthrofibrosis in neuromuscular disorders: a review. BMC Musculoskelet Disord. 2022 Jul 29; 23(1):725. PMID: 35906570; PMCID: PMC9336011; DOI: 10.1186/s12891-022-05677-z;

Chan DD, Mashiatulla M, Li J, Ross RD, Pendyala M, Patwa A, Grinstaff MW, Plaas A, Sumner DR. Contrast-enhanced micro-computed tomography of compartment and time-dependent changes in femoral cartilage and subchondral plate in a murine model of osteoarthritis. Anat Rec (Hoboken). 2023 Jan; 306(1):92-109. PMID: 35751529; PMCID: PMC10084428; DOI: 10.1002/ar.25027;

Muruganandan S, Pierce R, Teguh DA, Perez RF, Bell N, Nguyen B, Hohl K, Snyder BD, Grinstaff MW, Alberico H, Woods D, Kong Y, Sima C, Bhagat S, Ho K, Rosen V, Gamer L, Ionescu AM. A FoxA2+ long-term stem cell population is necessary for growth plate cartilage regeneration after injury. Nat Commun. 2022 May 06; 13(1):2515. PMID: 35523895; PMCID: PMC9076650; DOI: 10.1038/s41467-022-30247-1;

Grazon C, Chern M, Lally P, Baer RC, Fan A, Lecommandoux S, Klapperich C, Dennis AM, Galagan JE, Grinstaff MW. The quantum dot vs. organic dye conundrum for ratiometric FRET-based biosensors: which one would you chose? Chem Sci. 2022 Jun 07; 13(22):6715-6731.View Related Profiles.

Dennis, Allison
Klapperich, Catherine
Galagan, James
Grinstaff, Mark

PMID: 35756504; PMCID: PMC9172442; DOI: 10.1039/d1sc06921g;

Sabatelle RC, Liu R, Hung YP, Bressler E, Neal EJ, Martin A, Ekladious I, Grinstaff MW, Colson YL. Ultra-high drug loading improves nanoparticle efficacy against peritoneal mesothelioma. Biomaterials. 2022 Jun; 285:121534. PMID: 35487067; PMCID: PMC9881475; DOI: 10.1016/j.biomaterials.2022.121534;

Varghese M, Haque F, Lu W, Grinstaff MW. Synthesis and Characterization of Regioselectively Functionalized Mono-Sulfated and -Phosphorylated Anionic Poly-Amido-Saccharides. Biomacromolecules. 2022 May 09; 23(5):2075-2088. PMID: 35420791

Sankar K, Baer R, Grazon C, Sabatelle RC, Lecommandoux S, Klapperich CM, Galagan JE, Grinstaff MW. An Allosteric Transcription Factor DNA-Binding Electrochemical Biosensor for Progesterone. ACS Sens. 2022 Apr 22; 7(4):1132-1137.View Related Profiles.

Klapperich, Catherine
Galagan, James
Grinstaff, Mark

PMID: 35412319; PMCID: PMC9985479; DOI: 10.1021/acssensors.2c00133;

Lu C, Yang D, Klement JD, Colson YL, Oberlies NH, Pearce CJ, Colby AH, Grinstaff MW, Liu Z, Shi H, Ding HF, Liu K. H3K9me3 represses G6PD expression to suppress the pentose phosphate pathway and ROS production to promote human mesothelioma growth. Oncogene. 2022 Apr; 41(18):2651-2662.View Related Profiles.

Colby, Aaron
Grinstaff, Mark

PMID: 35351997; PMCID: PMC9058223; DOI: 10.1038/s41388-022-02283-0;

Cheng R, Weitz AC, Paris J, Tang Y, Zhang J, Song H, Naowarojna N, Li K, Qiao L, Lopez J, Grinstaff MW, Zhang L, Guo Y, Elliott S, Liu P. OvoAMtht from Methyloversatilis thermotolerans ovothiol biosynthesis is a bifunction enzyme: thiol oxygenase and sulfoxide synthase activities. Chem Sci. 2022 Mar 24; 13(12):3589-3598.View Related Profiles.

Grinstaff, Mark
Liu, Pinghua
Elliott, Sean

PMID: 35432880; PMCID: PMC8943887; DOI: 10.1039/d1sc05479a;

Marks HL, Cook K, Roussakis E, Cascales JP, Korunes-Miller JT, Grinstaff MW, Evans CL. Quantitative Luminescence Photography of a Swellable Hydrogel Dressing with a Traffic-Light Response to Oxygen. Adv Healthc Mater. 2022 May; 11(10):e2101605. PMID: 35120400

Zamani M, Dupaty J, Baer RC, Kuzmanovic U, Fan A, Grinstaff MW, Galagan JE, Klapperich CM. Paper-Based Progesterone Sensor Using an Allosteric Transcription Factor. ACS Omega. 2022 Feb 22; 7(7):5804-5808.View Related Profiles.

Klapperich, Catherine
Galagan, James
Grinstaff, Mark

PMID: 35224340; PMCID: PMC8867790; DOI: 10.1021/acsomega.1c05737;

Lu C, Yang D, Klement JD, Colson YL, Oberlies NH, Pearce CJ, Colby AH, Grinstaff MW, Ding HF, Shi H, Liu K. G6PD functions as a metabolic checkpoint to regulate granzyme B expression in tumor-specific cytotoxic T lymphocytes. J Immunother Cancer. 2022 01; 10(1).View Related Profiles.

Colby, Aaron
Grinstaff, Mark

PMID: 35017152; PMCID: PMC8753452; DOI: 10.1136/jitc-2021-003543;

Lawson T, Joenathan A, Patwa A, Snyder BD, Grinstaff MW. Tantalum Oxide Nanoparticles for the Quantitative Contrast-Enhanced Computed Tomography of Ex Vivo Human Cartilage: Assessment of Biochemical Composition and Biomechanics. ACS Nano. 2021 12 28; 15(12):19175-19184. PMID: 34882411

Petersen A, Chu NQ, Fitzgerald DM, McCaslin EZ, Blessing WA, Colby AH, Colson YL, Grinstaff MW. Sustainable glycerol terpolycarbonates as temporary bioadhesives. Biomater Sci. 2021 Dec 07; 9(24):8366-8372.View Related Profiles.

Colby, Aaron
Grinstaff, Mark

PMID: 34787119; PMCID: PMC9856206; DOI: 10.1039/d1bm00995h;

Boos MA, Grinstaff MW, Lamandé SR, Stok KS. Contrast-Enhanced Micro-Computed Tomography for 3D Visualization and Quantification of Glycosaminoglycans in Different Cartilage Types. Cartilage. 2021 12; 13(2_suppl):486S-494S. PMID: 34696603; PMCID: PMC8804852; DOI: 10.1177/19476035211053820;

Cook KA, Naguib N, Kirsch J, Hohl K, Colby AH, Sheridan R, Rodriguez EK, Nazarian A, Grinstaff MW. In situ gelling and dissolvable hydrogels for use as on-demand wound dressings for burns. Biomater Sci. 2021 Oct 12; 9(20):6842-6850.View Related Profiles.

Colby, Aaron
Grinstaff, Mark

PMID: 34486599; PMCID: PMC8511343; DOI: 10.1039/d1bm00711d;

Varghese M, Rokosh RS, Haller CA, Chin SL, Chen J, Dai E, Xiao R, Chaikof EL, Grinstaff MW. Sulfated poly-amido-saccharides (sulPASs) are anticoagulants in vitro and in vivo. Chem Sci. 2021 Oct 06; 12(38):12719-12725. PMID: 34703558; PMCID: PMC8494039; DOI: 10.1039/d1sc02302k;

Song J, Korunes-Miller J, Banerji R, Wu Y, Fazeli S, Zheng H, Orr B, Morgan E, Andry C, Henderson J, Miller NS, White A, Grinstaff MW. On-Site, On-Demand 3D-Printed Nasopharyngeal Swabs to Improve the Access of Coronavirus Disease-19 Testing. Glob Chall. 2021 Nov; 5(11):2100039.View Related Profiles.

Andry, Christopher
Morgan, Elise
Zheng, Hanqiao
Henderson, Joel
Grinstaff, Mark
Miller, Nancy

PMID: 34754507; PMCID: PMC8562062; DOI: 10.1002/gch2.202100039;

Kroupa KR, Wu MI, Zhang J, Jensen M, Wong W, Engiles JB, Schaer TP, Grinstaff MW, Snyder BD, Bergholt MS, Albro MB. Raman needle arthroscopy for in vivo molecular assessment of cartilage. J Orthop Res. 2022 Jun; 40(6):1338-1348. PMID: 34370873; PMCID: PMC9291802; DOI: 10.1002/jor.25155;

Gao X, Patwa AN, Deng Z, Utsunomiya H, Grinstaff MW, Ruzbarsky JJ, Snyder BD, Ravuri S, Philippon MJ, Huard J. Influence of fixation on CA4+ contrast enhanced microCT of articular cartilage and subsequent feasibility for histological evaluation. Am J Transl Res. 2021; 13(8):8921-8937. PMID: 34540005; PMCID: PMC8430171

Cook K, Naguib N, Price CE, Katharios S, Kirsch J, Cortes K, Hohl K, O'Toole GA, Grinstaff MW. Temporary In Situ Hydrogel Dressings for Colon Polypectomies. ACS Biomater Sci Eng. 2021 09 13; 7(9):4362-4370. PMID: 34342427; PMCID: PMC9493297; DOI: 10.1021/acsbiomaterials.1c00549;

Colby AH, Liu R, Doyle RP, Merting A, Zhang H, Savage N, Chu NQ, Hollister BA, McCulloch W, Burdette JE, Pearce CJ, Liu K, Oberlies NH, Colson YL, Grinstaff MW. Pilot-scale production of expansile nanoparticles: Practical methods for clinical scale-up. J Control Release. 2021 09 10; 337:144-154.View Related Profiles.

Colby, Aaron
Grinstaff, Mark

PMID: 34280414; PMCID: PMC8489532; DOI: 10.1016/j.jconrel.2021.07.012;

Saukko AEA, Nykänen O, Sarin JK, Nissi MJ, Te Moller NCR, Weinans H, Mancini IAD, Visser J, Brommer H, van Weeren PR, Malda J, Grinstaff MW, Töyräs J. Dual-contrast computed tomography enables detection of equine posttraumatic osteoarthritis in vitro. J Orthop Res. 2022 03; 40(3):703-711. PMID: 33982283

Gromisch CM, Tan GLA, Pasion KA, Moran AM, Gromisch MS, Grinstaff MW, Carr FJ, Herrera VLM, Ruiz-Opazo N. Humanized anti-DEspR IgG4S228P antibody increases overall survival in a pancreatic cancer stem cell-xenograft peritoneal carcinomatosis ratnu/nu model. BMC Cancer. 2021 Apr 14; 21(1):407.View Related Profiles.

Gromisch, Christopher
Grinstaff, Mark
Ruiz-Opazo, Nelson
Herrera, Victoria

PMID: 33853558; PMCID: PMC8048286; DOI: 10.1186/s12885-021-08107-w;

Blessing WA, Williamson AK, Kirsch JR, Grinstaff MW. The Prognosis of Arthrofibroses: Prevalence, Clinical Shortcomings, and Future Prospects. Trends Pharmacol Sci. 2021 05; 42(5):398-415. PMID: 33795150; PMCID: PMC8529832; DOI: 10.1016/j.tips.2021.02.007;

Song J, Michas C, Chen CS, White AE, Grinstaff MW. Controlled Cell Alignment Using Two-Photon Direct Laser Writing-Patterned Hydrogels in 2D and 3D. Macromol Biosci. 2021 05; 21(5):e2100051.View Related Profiles.

Chen, Christopher
Grinstaff, Mark

PMID: 33738917

Paakkari P, Inkinen SI, Honkanen MKM, Prakash M, Shaikh R, Nieminen MT, Grinstaff MW, Mäkelä JTA, Töyräs J, Honkanen JTJ. Quantitative dual contrast photon-counting computed tomography for assessment of articular cartilage health. Sci Rep. 2021 03 10; 11(1):5556. PMID: 33692379; PMCID: PMC7946949; DOI: 10.1038/s41598-021-84800-x;

Cheng R, Lai R, Peng C, Lopez J, Li Z, Naowarojna N, Li K, Wong C, Lee N, Whelan SA, Qiao L, Grinstaff MW, Wang J, Cui Q, Liu P. Implications for an imidazol-2-yl carbene intermediate in the rhodanase-catalyzed C-S bond formation reaction of anaerobic ergothioneine biosynthesis. ACS Catal. 2021 Mar 19; 11(6):3319-3334. PMID: 34745712; PMCID: PMC8570591; DOI: 10.1021/acscatal.0c04886;

Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM, Ahumada-Castro U, Aits S, Aizawa S, Akkoc Y, Akoumianaki T, Akpinar HA, Al-Abd AM, Al-Akra L, Al-Gharaibeh A, Alaoui-Jamali MA, Alberti S, Alcocer-Gómez E, Alessandri C, Ali M, Alim Al-Bari MA, Aliwaini S, Alizadeh J, Almacellas E, Almasan A, Alonso A, Alonso GD, Altan-Bonnet N, Altieri DC, Álvarez ÉMC, Alves S, Alves da Costa C, Alzaharna MM, Amadio M, Amantini C, Amaral C, Ambrosio S, Amer AO, Ammanathan V, An Z, Andersen SU, Andrabi SA, Andrade-Silva M, Andres AM, Angelini S, Ann D, Anozie UC, Ansari MY, Antas P, Antebi A, Antón Z, Anwar T, Apetoh L, Apostolova N, Araki T, Araki Y, Arasaki K, Araújo WL, Araya J, Arden C, Arévalo MA, Arguelles S, Arias E, Arikkath J, Arimoto H, Ariosa AR, Armstrong-James D, Arnauné-Pelloquin L, Aroca A, Arroyo DS, Arsov I, Artero R, Asaro DML, Aschner M, Ashrafizadeh M, Ashur-Fabian O, Atanasov AG, Au AK, Auberger P, Auner HW, Aurelian L, Autelli R, Avagliano L, Ávalos Y, Aveic S, Aveleira CA, Avin-Wittenberg T, Aydin Y, Ayton S, Ayyadevara S, Azzopardi M, Baba M, Backer JM, Backues SK, Bae DH, Bae ON, Bae SH, Baehrecke EH, Baek A, Baek SH, Baek SH, Bagetta G, Bagniewska-Zadworna A, Bai H, Bai J, Bai X, Bai Y, Bairagi N, Baksi S, Balbi T, Baldari CT, Balduini W, Ballabio A, Ballester M, Balazadeh S, Balzan R, Bandopadhyay R, Banerjee S, Banerjee S, Bánréti Á, Bao Y, Baptista MS, Baracca A, Barbati C, Bargiela A, Barilà D, Barlow PG, Barmada SJ, Barreiro E, Barreto GE, Bartek J, Bartel B, Bartolome A, Barve GR, Basagoudanavar SH, Bassham DC, Bast RC, Basu A, Batoko H, Batten I, Baulieu EE, Baumgarner BL, Bayry J, Beale R, Beau I, Beaumatin F, Bechara LRG, Beck GR, Beers MF, Begun J, Behrends C, Behrens GMN, Bei R, Bejarano E, Bel S, Behl C, Belaid A, Belgareh-Touzé N, Bellarosa C, Belleudi F, Belló Pérez M, Bello-Morales R, Beltran JSO, Beltran S, Benbrook DM, Bendorius M, Benitez BA, Benito-Cuesta I, Bensalem J, Berchtold MW, Berezowska S, Bergamaschi D, Bergami M, Bergmann A, Berliocchi L, Berlioz-Torrent C, Bernard A, Berthoux L, Besirli CG, Besteiro S, Betin VM, Beyaert R, Bezbradica JS, Bhaskar K, Bhatia-Kissova I, Bhattacharya R, Bhattacharya S, Bhattacharyya S, Bhuiyan MS, Bhutia SK, Bi L, Bi X, Biden TJ, Bijian K, Billes VA, Binart N, Bincoletto C, Birgisdottir AB, Bjorkoy G, Blanco G, Blas-Garcia A, Blasiak J, Blomgran R, Blomgren K, Blum JS, Boada-Romero E, Boban M, Boesze-Battaglia K, Boeuf P, Boland B, Bomont P, Bonaldo P, Bonam SR, Bonfili L, Bonifacino JS, Boone BA, Bootman MD, Bordi M, Borner C, Bornhauser BC, Borthakur G, Bosch J, Bose S, Botana LM, Botas J, Boulanger CM, Boulton ME, Bourdenx M, Bourgeois B, Bourke NM, Bousquet G, Boya P, Bozhkov PV, Bozi LHM, Bozkurt TO, Brackney DE, Brandts CH, Braun RJ, Braus GH, Bravo-Sagua R, Bravo-San Pedro JM, Brest P, Bringer MA, Briones-Herrera A, Broaddus VC, Brodersen P, Brodsky JL, Brody SL, Bronson PG, Bronstein JM, Brown CN, Brown RE, Brum PC, Brumell JH, Brunetti-Pierri N, Bruno D, Bryson-Richardson RJ, Bucci C, Buchrieser C, Bueno M, Buitrago-Molina LE, Buraschi S, Buch S, Buchan JR, Buckingham EM, Budak H, Budini M, Bultynck G, Burada F, Burgoyne JR, Burón MI, Bustos V, Büttner S, Butturini E, Byrd A, Cabas I, Cabrera-Benitez S, Cadwell K, Cai J, Cai L, Cai Q, Cairó M, Calbet JA, Caldwell GA, Caldwell KA, Call JA, Calvani R, Calvo AC, Calvo-Rubio Barrera M, Camara NO, Camonis JH, Camougrand N, Campanella M, Campbell EM, Campbell-Valois FX, Campello S, Campesi I, Campos JC, Camuzard O, Cancino J, Candido de Almeida D, Canesi L, Caniggia I, Canonico B, Cantí C, Cao B, Caraglia M, Caramés B, Carchman EH, Cardenal-Muñoz E, Cardenas C, Cardenas L, Cardoso SM, Carew JS, Carle GF, Carleton G, Carloni S, Carmona-Gutierrez D, et al. GuideView Related Profiles.

Singh, Anurag
Grinstaff, Mark
Rahimi, Nader

PMID: 33634751; PMCID: PMC7996087; DOI: 10.1080/15548627.2020.1797280;

Zhu H, Klement JD, Lu C, Redd PS, Yang D, Smith AD, Poschel DB, Zou J, Liu D, Wang PG, Ostrov D, Coant N, Hannun YA, Colby AH, Grinstaff MW, Liu K. Asah2 Represses the p53-Hmox1 Axis to Protect Myeloid-Derived Suppressor Cells from Ferroptosis. J Immunol. 2021 03 15; 206(6):1395-1404.View Related Profiles.

Colby, Aaron
Grinstaff, Mark

PMID: 33547170; PMCID: PMC7946776; DOI: 10.4049/jimmunol.2000500;

Rai P, Janardhan KS, Meacham J, Madenspacher JH, Lin WC, Karmaus PWF, Martinez J, Li QZ, Yan M, Zeng J, Grinstaff MW, Shirihai OS, Taylor GA, Fessler MB. IRGM1 links mitochondrial quality control to autoimmunity. Nat Immunol. 2021 03; 22(3):312-321.View Related Profiles.

Grinstaff, Mark
Shirihai, Orian

PMID: 33510463; PMCID: PMC7906953; DOI: 10.1038/s41590-020-00859-0;

Al Subeh ZY, Chu NQ, Korunes-Miller JT, Tsai LL, Graf TN, Hung YP, Pearce CJ, Grinstaff MW, Colby AH, Colson YL, Oberlies NH. Delivery of eupenifeldin via polymer-coated surgical buttresses prevents local lung cancer recurrence. J Control Release. 2021 03 10; 331:260-269.View Related Profiles.

Colby, Aaron
Grinstaff, Mark

PMID: 33484778; PMCID: PMC7946725; DOI: 10.1016/j.jconrel.2021.01.026;

Otto IA, Capendale PE, Garcia JP, de Ruijter M, van Doremalen RFM, Castilho M, Lawson T, Grinstaff MW, Breugem CC, Kon M, Levato R, Malda J. Biofabrication of a shape-stable auricular structure for the reconstruction of ear deformities. Mater Today Bio. 2021 Jan; 9:100094. PMID: 33665603; PMCID: PMC7903133; DOI: 10.1016/j.mtbio.2021.100094;

Zeng J, Shirihai OS, Grinstaff MW. Modulating lysosomal pH: a molecular and nanoscale materials design perspective. J Life Sci (Westlake Village). 2020 Dec; 2(4):25-37.View Related Profiles.

Grinstaff, Mark
Shirihai, Orian

PMID: 33403369; PMCID: PMC7781074; DOI: 10.36069/jols/20201204;

Scott KM, Cohen DJ, Hays M, Nielson DW, Grinstaff MW, Lawson TB, Snyder BD, Boyan BD, Schwartz Z. Regulation of inflammatory and catabolic responses to IL-1ß in rat articular chondrocytes by microRNAs miR-122 and miR-451. Osteoarthritis Cartilage. 2021 01; 29(1):113-123. PMID: 33161100

Nelson BB, Mäkelä JTA, Lawson TB, Patwa AN, Snyder BD, McIlwraith CW, Grinstaff MW, Goodrich LR, Kawcak CE. Cationic contrast-enhanced computed tomography distinguishes between reparative, degenerative, and healthy equine articular cartilage. J Orthop Res. 2021 08; 39(8):1647-1657. PMID: 33104251

Lawson TB, Mäkelä JTA, Klein T, Snyder BD, Grinstaff MW. Nanotechnology and Osteoarthritis. Part 2: Opportunities for advanced devices and therapeutics. J Orthop Res. 2021 03; 39(3):473-484. PMID: 32860444

Sonnenberg AH, Taylor E, Mondoñedo JR, Jawde SB, Amin SD, Song J, Grinstaff MW, Suki B. Breath Hold Facilitates Targeted Deposition of Aerosolized Droplets in a 3D Printed Bifurcating Airway Tree. Ann Biomed Eng. 2021 Feb; 49(2):812-821.View Related Profiles.

Suki, Bela
Mondonedo, Jarred
Grinstaff, Mark

PMID: 32959135

Balijepalli AS, McNeely JH, Hamoud A, Grinstaff MW. Guidelines for ß-Lactam Synthesis: Glycal Protecting Groups Dictate Stereoelectronics and [2+2] Cycloaddition Kinetics. J Org Chem. 2020 10 02; 85(19):12044-12057. PMID: 32844657

Chen M, Grazon C, Sensharma P, Nguyen TT, Feng Y, Chern M, Baer RC, Varongchayakul N, Cook K, Lecommandoux S, Klapperich CM, Galagan JE, Dennis AM, Grinstaff MW. Hydrogel-Embedded Quantum Dot-Transcription Factor Sensors for Quantitative Progesterone Detection. ACS Appl Mater Interfaces. 2020 Sep 30; 12(39):43513-43521.View Related Profiles.

Dennis, Allison
Klapperich, Catherine
Galagan, James
Grinstaff, Mark
Baer, R

PMID: 32893612

Lawson TB, Mäkelä JTA, Klein T, Snyder BD, Grinstaff MW. Nanotechnology and osteoarthritis; part 1: Clinical landscape and opportunities for advanced diagnostics. J Orthop Res. 2021 03; 39(3):465-472. PMID: 32827322

Balijepalli AS, Grinstaff MW. Poly-Amido-Saccharides (PASs): Functional Synthetic Carbohydrate Polymers Inspired by Nature. Acc Chem Res. 2020 10 20; 53(10):2167-2179. PMID: 32892620

Bhattarai A, Mäkelä JTA, Pouran B, Kröger H, Weinans H, Grinstaff MW, Töyräs J, Turunen MJ. Effects of human articular cartilage constituents on simultaneous diffusion of cationic and nonionic contrast agents. J Orthop Res. 2021 04; 39(4):771-779. PMID: 32767676; PMCID: PMC8048551; DOI: 10.1002/jor.24824;

Sonnenberg AH, Herrmann J, Grinstaff MW, Suki B. A Markov chain model of particle deposition in the lung. Sci Rep. 2020 08 11; 10(1):13573.View Related Profiles.

Suki, Bela
Grinstaff, Mark

PMID: 32782272; PMCID: PMC7419522; DOI: 10.1038/s41598-020-70171-2;

Chen M, Nguyen TT, Varongchayakul N, Grazon C, Chern M, Baer RC, Lecommandoux S, Klapperich CM, Galagan JE, Dennis AM, Grinstaff MW. Surface Immobilized Nucleic Acid-Transcription Factor Quantum Dots for Biosensing. Adv Healthc Mater. 2020 09; 9(17):e2000403.View Related Profiles.

Dennis, Allison
Klapperich, Catherine
Galagan, James
Grinstaff, Mark
Baer, R

PMID: 32691962

Cheng R, Wu L, Lai R, Peng C, Naowarojna N, Hu W, Li X, Whelan SA, Lee N, Lopez J, Zhao C, Yong Y, Xue J, Jiang X, Grinstaff MW, Deng Z, Chen J, Cui Q, Zhou J, Liu P. Single-step Replacement of an Unreactive C-H Bond by a C-S Bond Using Polysulfide as the Direct Sulfur Source in Anaerobic Ergothioneine Biosynthesis. ACS Catal. 2020 Aug 21; 10(16):8981-8994. PMID: 34306804; PMCID: PMC8302205; DOI: 10.1021/acscatal.0c01809;

Bhattarai A, Pouran B, Mäkelä JTA, Shaikh R, Honkanen MKM, Prakash M, Kröger H, Grinstaff MW, Weinans H, Jurvelin JS, Töyräs J. Dual contrast in computed tomography allows earlier characterization of articular cartilage over single contrast. J Orthop Res. 2020 10; 38(10):2230-2238. PMID: 32525582

Anilkumar P, Lawson TB, Abbina S, Mäkelä JTA, Sabatelle RC, Takeuchi LE, Snyder BD, Grinstaff MW, Kizhakkedathu JN. Mega macromolecules as single molecule lubricants for hard and soft surfaces. Nat Commun. 2020 05 01; 11(1):2139. PMID: 32358489; PMCID: PMC7195476; DOI: 10.1038/s41467-020-15975-6;

Gromisch C, Qadan M, Machado MA, Liu K, Colson Y, Grinstaff MW. Pancreatic Adenocarcinoma: Unconventional Approaches for an Unconventional Disease. Cancer Res. 2020 08 15; 80(16):3179-3192.View Related Profiles.

Gromisch, Christopher
Grinstaff, Mark

PMID: 32220831; PMCID: PMC7755309; DOI: 10.1158/0008-5472.CAN-19-2731;

Grazon C, Baer RC, Kuzmanovic U, Nguyen T, Chen M, Zamani M, Chern M, Aquino P, Zhang X, Lecommandoux S, Fan A, Cabodi M, Klapperich C, Grinstaff MW, Dennis AM, Galagan JE. A progesterone biosensor derived from microbial screening. Nat Commun. 2020 03 09; 11(1):1276.View Related Profiles.

Dennis, Allison
Klapperich, Catherine
Galagan, James
Cabodi, Mario
Grinstaff, Mark
Baer, R

PMID: 32152281; PMCID: PMC7062782; DOI: 10.1038/s41467-020-14942-5;

Stoiber P, Ekladious I, Zhao Q, Colson YL, Schaus SE, Hansen U, Grinstaff MW. Expansile Nanoparticles Encapsulate Factor Quinolinone Inhibitor 1 and Accumulate in Murine Liver upon Intravenous Administration. Biomacromolecules. 2020 04 13; 21(4):1499-1506.View Related Profiles.

Grinstaff, Mark
Schaus, Scott

PMID: 32101401

Roussakis E, Cascales JP, Marks HL, Li X, Grinstaff M, Evans CL. Humidity-Insensitive Tissue Oxygen Tension Sensing for Wearable Devices†. Photochem Photobiol. 2020 03; 96(2):373-379. PMID: 31869435

Chu NQ, Liu R, Colby A, de Forcrand C, Padera RF, Grinstaff MW, Colson YL. Paclitaxel-loaded expansile nanoparticles improve survival following cytoreductive surgery in pleural mesothelioma xenografts. J Thorac Cardiovasc Surg. 2020 Sep; 160(3):e159-e168.View Related Profiles.

Colby, Aaron
Grinstaff, Mark

PMID: 32044093; PMCID: PMC7354899; DOI: 10.1016/j.jtcvs.2019.12.076;

Salvi A, Amrine CSM, Austin JR, Kilpatrick K, Russo A, Lantvit D, Calderon-Gierszal E, Mattes Z, Pearce CJ, Grinstaff MW, Colby AH, Oberlies NH, Burdette JE. Verticillin A Causes Apoptosis and Reduces Tumor Burden in High-Grade Serous Ovarian Cancer by Inducing DNA Damage. Mol Cancer Ther. 2020 01; 19(1):89-100.View Related Profiles.

Colby, Aaron
Grinstaff, Mark

PMID: 31909733; PMCID: PMC6951445; DOI: 10.1158/1535-7163.MCT-19-0205;

Beharaj A, McCaslin EZ, Blessing WA, Grinstaff MW. Sustainable polycarbonate adhesives for dry and aqueous conditions with thermoresponsive properties. Nat Commun. 2019 12 02; 10(1):5478. PMID: 31792214; PMCID: PMC6889139; DOI: 10.1038/s41467-019-13449-y;

Balijepalli AS, Sabatelle RC, Chen M, Suki B, Grinstaff MW. A Synthetic Bioinspired Carbohydrate Polymer with Mucoadhesive Properties. Angew Chem Int Ed Engl. 2020 01 07; 59(2):704-710.View Related Profiles.

Suki, Bela
Grinstaff, Mark

PMID: 31701611; PMCID: PMC7754715; DOI: 10.1002/anie.201911720;

Grazon C, Salas-Ambrosio P, Ibarboure E, Buol A, Garanger E, Grinstaff MW, Lecommandoux S, Bonduelle C. Aqueous Ring-Opening Polymerization-Induced Self-Assembly (ROPISA) of N-Carboxyanhydrides. Angew Chem Int Ed Engl. 2020 01 07; 59(2):622-626. PMID: 31650664

Song J, Michas C, Chen CS, White AE, Grinstaff MW. From Simple to Architecturally Complex Hydrogel Scaffolds for Cell and Tissue Engineering Applications: Opportunities Presented by Two-Photon Polymerization. Adv Healthc Mater. 2020 01; 9(1):e1901217.View Related Profiles.

Chen, Christopher
Grinstaff, Mark

PMID: 31746140

Freedman JD, Ellis DJ, Lusic H, Varma G, Grant AK, Lakin BA, Snyder BD, Grinstaff MW. dGEMRIC and CECT Comparison of Cationic and Anionic Contrast Agents in Cadaveric Human Metacarpal Cartilage. J Orthop Res. 2020 04; 38(4):719-725.View Related Profiles.

Freedman, Jonathan
Grinstaff, Mark

PMID: 31687789; PMCID: PMC7071952; DOI: 10.1002/jor.24511;

Honkanen MKM, Saukko AEA, Turunen MJ, Shaikh R, Prakash M, Lovric G, Joukainen A, Kröger H, Grinstaff MW, Töyräs J. Synchrotron MicroCT Reveals the Potential of the Dual Contrast Technique for Quantitative Assessment of Human Articular Cartilage Composition. J Orthop Res. 2020 03; 38(3):563-573. PMID: 31535728; PMCID: PMC7065106; DOI: 10.1002/jor.24479;

Honkanen MKM, Saukko AEA, Turunen MJ, Xu W, Lovric G, Honkanen JTJ, Grinstaff MW, Lehto VP, Töyräs J. Triple Contrast CT Method Enables Simultaneous Evaluation of Articular Cartilage Composition and Segmentation. Ann Biomed Eng. 2020 Feb; 48(2):556-567. PMID: 31576504; PMCID: PMC6949199; DOI: 10.1007/s10439-019-02362-6;

Garcia JP, Longoni A, Gawlitta D, J W P Rosenberg A, Grinstaff MW, Töyräs J, Weinans H, Creemers LB, Pouran B. Contrast enhanced computed tomography for real-time quantification of glycosaminoglycans in cartilage tissue engineered constructs. Acta Biomater. 2019 12; 100:202-212. PMID: 31580960

Zhang H, Belev G, Stewart RC, Grinstaff MW, Snyder BD, Wilson DR. Protocol development for synchrotron contrast-enhanced CT of human hip cartilage. Med Eng Phys. 2019 11; 73:1-8. PMID: 31526590

Grazon C, Chern M, Ward K, Lecommandoux S, Grinstaff MW, Dennis AM. A versatile and accessible polymer coating for functionalizable zwitterionic quantum dots with high DNA grafting efficiency. Chem Commun (Camb). 2019 Sep 21; 55(74):11067-11070.View Related Profiles.

Dennis, Allison
Grinstaff, Mark

PMID: 31453992

Ho RX, Tahboub R, Amraei R, Meyer RD, Varongchayakul N, Grinstaff M, Rahimi N. The cell adhesion molecule IGPR-1 is activated by and regulates responses of endothelial cells to shear stress. J Biol Chem. 2019 09 13; 294(37):13671-13680.View Related Profiles.

Grinstaff, Mark
Rahimi, Nader
Tahboub, Rawan

PMID: 31341021; PMCID: PMC6746441; DOI: 10.1074/jbc.RA119.008548;

Zeng J, Martin A, Han X, Shirihai OS, Grinstaff MW. Biodegradable PLGA nanoparticles restore lysosomal acidity and protect neural PC-12 cells against mitochondrial toxicity. Ind Eng Chem Res. 2019 Aug 07; 58(31):13910-13917. PMID: 38576774; PMCID: PMC10993316; DOI: 10.1021/acs.iecr.9b02003;

Stewart RC, Nelson BB, Kawcak CE, Freedman JD, Snyder BD, Goodrich LR, Grinstaff MW. Contrast-Enhanced Computed Tomography Scoring System for Distinguishing Early Osteoarthritis Disease States: A Feasibility Study. J Orthop Res. 2019 10; 37(10):2138-2148.View Related Profiles.

Freedman, Jonathan
Grinstaff, Mark

PMID: 31136003; PMCID: PMC6739126; DOI: 10.1002/jor.24382;

McDermott AM, Herberg S, Mason DE, Collins JM, Pearson HB, Dawahare JH, Tang R, Patwa AN, Grinstaff MW, Kelly DJ, Alsberg E, Boerckel JD. Recapitulating bone development through engineered mesenchymal condensations and mechanical cues for tissue regeneration. Sci Transl Med. 2019 06 05; 11(495). PMID: 31167930; PMCID: PMC6959418; DOI: 10.1126/scitranslmed.aav7756;

Blessing WA, Okajima SM, Cubria MB, Villa-Camacho JC, Perez-Viloria M, Williamson PM, Sabogal AN, Suarez S, Ang LH, White S, Flynn E, Rodriguez EK, Grinstaff MW, Nazarian A. Intraarticular injection of relaxin-2 alleviates shoulder arthrofibrosis. Proc Natl Acad Sci U S A. 2019 06 18; 116(25):12183-12192.View Related Profiles.

Grinstaff, Mark
Suarez Zarate, Sebastian

PMID: 31160441; PMCID: PMC6589647; DOI: 10.1073/pnas.1900355116;

Lakin BA, Cooper BG, Zakaria L, Grasso DJ, Wathier M, Bendele AM, Freedman JD, Snyder BD, Grinstaff MW. A Synthetic Bottle-brush Polyelectrolyte Reduces Friction and Wear of Intact and Previously Worn Cartilage. ACS Biomater Sci Eng. 2019 Jun 10; 5(6):3060-3067.View Related Profiles.

Cooper, Benjamin
Freedman, Jonathan
Grinstaff, Mark

PMID: 31608307; PMCID: PMC6788642; DOI: 10.1021/acsbiomaterials.9b00085;

Saukko AEA, Turunen MJ, Honkanen MKM, Lovric G, Tiitu V, Honkanen JTJ, Grinstaff MW, Jurvelin JS, Töyräs J. Simultaneous Quantitation of Cationic and Non-ionic Contrast Agents in Articular Cartilage Using Synchrotron MicroCT Imaging. Sci Rep. 2019 05 08; 9(1):7118. PMID: 31068614; PMCID: PMC6506503; DOI: 10.1038/s41598-019-43276-6;

Nelson BB, Mäkelä JTA, Lawson TB, Patwa AN, Barrett MF, McIlwraith CW, Hurtig MB, Snyder BD, Moorman VJ, Grinstaff MW, Goodrich LR, Kawcak CE. Evaluation of equine articular cartilage degeneration after mechanical impact injury using cationic contrast-enhanced computed tomography. Osteoarthritis Cartilage. 2019 08; 27(8):1219-1228. PMID: 31075424

Caputo HE, Straub JE, Grinstaff MW. Design, synthesis, and biomedical applications of synthetic sulphated polysaccharides. Chem Soc Rev. 2019 Apr 15; 48(8):2338-2365.View Related Profiles.

Straub, John
Grinstaff, Mark

PMID: 30742140

Ekladious I, Colson YL, Grinstaff MW. Polymer-drug conjugate therapeutics: advances, insights and prospects. Nat Rev Drug Discov. 2019 04; 18(4):273-294. PMID: 30542076

Honkanen MKM, Matikka H, Honkanen JTJ, Bhattarai A, Grinstaff MW, Joukainen A, Kröger H, Jurvelin JS, Töyräs J. Imaging of proteoglycan and water contents in human articular cartilage with full-body CT using dual contrast technique. J Orthop Res. 2019 05; 37(5):1059-1070. PMID: 30816584; PMCID: PMC6594070; DOI: 10.1002/jor.24256;

Zeng J, Shirihai OS, Grinstaff MW. Degradable Nanoparticles Restore Lysosomal pH and Autophagic Flux in Lipotoxic Pancreatic Beta Cells. Adv Healthc Mater. 2019 06; 8(12):e1801511.View Related Profiles.

Grinstaff, Mark
Shirihai, Orian

PMID: 30698920

Benizri S, Gissot A, Martin A, Vialet B, Grinstaff MW, Barthélémy P. Bioconjugated Oligonucleotides: Recent Developments and Therapeutic Applications. Bioconjug Chem. 2019 02 20; 30(2):366-383. PMID: 30608140; PMCID: PMC6766081; DOI: 10.1021/acs.bioconjchem.8b00761;

Beharaj A, Ekladious I, Grinstaff MW. Poly(Alkyl Glycidate Carbonate)s as Degradable Pressure-Sensitive Adhesives. Angew Chem Int Ed Engl. 2019 01 28; 58(5):1407-1411. PMID: 30516857

El-Elimat T, Raja HA, Ayers S, Kurina SJ, Burdette JE, Mattes Z, Sabatelle R, Bacon JW, Colby AH, Grinstaff MW, Pearce CJ, Oberlies NH. Meroterpenoids from Neosetophoma sp.: A Dioxa[4.3.3]propellane Ring System, Potent Cytotoxicity, and Prolific Expression. Org Lett. 2019 01 18; 21(2):529-534.View Related Profiles.

Colby, Aaron
Grinstaff, Mark

PMID: 30620608; PMCID: PMC6343109; DOI: 10.1021/acs.orglett.8b03769;

Lu C, Yang D, Klement JD, Oh IK, Savage NM, Waller JL, Colby AH, Grinstaff MW, Oberlies NH, Pearce CJ, Xie Z, Kulp SK, Coss CC, Phelps MA, Albers T, Lebedyeva IO, Liu K. SUV39H1 Represses the Expression of Cytotoxic T-Lymphocyte Effector Genes to Promote Colon Tumor Immune Evasion. Cancer Immunol Res. 2019 03; 7(3):414-427.View Related Profiles.

Colby, Aaron
Grinstaff, Mark

PMID: 30610059; PMCID: PMC6397681; DOI: 10.1158/2326-6066.CIR-18-0126;

Dourthe B, Nickmanesh R, Wilson DR, D'Agostino P, Patwa AN, Grinstaff MW, Snyder BD, Vereecke E. Assessment of healthy trapeziometacarpal cartilage properties using indentation testing and contrast-enhanced computed tomography. Clin Biomech (Bristol, Avon). 2019 01; 61:181-189. PMID: 30594765

Assali EA, Shlomo D, Zeng J, Taddeo EP, Trudeau KM, Erion KA, Colby AH, Grinstaff MW, Liesa M, Las G, Shirihai OS. Nanoparticle-mediated lysosomal reacidification restores mitochondrial turnover and function in ß cells under lipotoxicity. FASEB J. 2019 03; 33(3):4154-4165.View Related Profiles.

Colby, Aaron
Las, Guy
Erion, Karel
Trudeau, Kyle
Grinstaff, Mark
Shirihai, Orian

PMID: 30550357; PMCID: PMC8793810; DOI: 10.1096/fj.201801292R;

Nelson BB, Stewart RC, Kawcak CE, Freedman JD, Patwa AN, Snyder BD, Goodrich LR, Grinstaff MW. Quantitative Evaluation of Equine Articular Cartilage Using Cationic Contrast-Enhanced Computed Tomography. Cartilage. 2021 04; 12(2):211-221.View Related Profiles.

Freedman, Jonathan
Grinstaff, Mark

PMID: 33722083; PMCID: PMC7970376; DOI: 10.1177/1947603518812562;

Varongchayakul N, Song J, Meller A, Grinstaff MW. Single-molecule protein sensing in a nanopore: a tutorial. Chem Soc Rev. 2018 Nov 26; 47(23):8512-8524. PMID: 30328860; PMCID: PMC6309966; DOI: 10.1039/c8cs00106e;

Wang R, Gilboa T, Song J, Huttner D, Grinstaff MW, Meller A. Single-Molecule Discrimination of Labeled DNAs and Polypeptides Using Photoluminescent-Free TiO2 Nanopores. ACS Nano. 2018 11 27; 12(11):11648-11656. PMID: 30372037

Mahvi DA, Liu R, Grinstaff MW, Colson YL, Raut CP. Local Cancer Recurrence: The Realities, Challenges, and Opportunities for New Therapies. CA Cancer J Clin. 2018 11; 68(6):488-505. PMID: 30328620; PMCID: PMC6239861; DOI: 10.3322/caac.21498;

Cooper BG, Chin SL, Xiao R, Buch K, Kim D, Grinstaff MW. Friction-lowering capabilities and human subject preferences for a hydrophilic surface coating on latex substrates: implications for increasing condom usage. R Soc Open Sci. 2018 Oct; 5(10):180291.View Related Profiles.

Cooper, Benjamin
Grinstaff, Mark

PMID: 30473805; PMCID: PMC6227966; DOI: 10.1098/rsos.180291;

Varongchayakul N, Hersey J, Squires A, Meller A, Grinstaff M. A Solid-State Hard Microfluidic-Nanopore Biosensor with Multilayer Fluidics and On-Chip Bioassay/Purification Chamber. Adv Funct Mater. 2018 Dec 12; 28(50). PMID: 31632230; PMCID: PMC6800661; DOI: 10.1002/adfm.201804182;

Okajima SM, Cubria MB, Mortensen SJ, Villa-Camacho JC, Hanna P, Lechtig A, Perez-Viloria M, Williamson P, Grinstaff MW, Rodriguez EK, Nazarian A. Rat Model of Adhesive Capsulitis of the Shoulder. J Vis Exp. 2018 09 28; (139). PMID: 30320752; PMCID: PMC6235346; DOI: 10.3791/58335;

Serebrakian AT, Pickrell BB, Varon DE, Mohamadi A, Grinstaff MW, Rodriguez EK, Nazarian A, Halvorson EG, Sinha I. Meta-analysis and Systematic Review of Skin Graft Donor-site Dressings with Future Guidelines. Plast Reconstr Surg Glob Open. 2018 Sep; 6(9):e1928. PMID: 30349793; PMCID: PMC6191241; DOI: 10.1097/GOX.0000000000001928;

Herrera VL, Colby AH, Ruiz-Opazo N, Coleman DG, Grinstaff MW. Nucleic acid nanomedicines in Phase II/III clinical trials: translation of nucleic acid therapies for reprogramming cells. Nanomedicine (Lond). 2018 08; 13(16):2083-2098.View Related Profiles.

Colby, Aaron
Grinstaff, Mark
Ruiz-Opazo, Nelson
Herrera, Victoria

PMID: 30204054; PMCID: PMC6219437; DOI: 10.2217/nnm-2018-0122;

Wathier M, Lakin BA, Cooper BG, Bansal PN, Bendele AM, Entezari V, Suzuki H, Snyder BD, Grinstaff MW. A synthetic polymeric biolubricant imparts chondroprotection in a rat meniscal tear model. Biomaterials. 2018 11; 182:13-20.View Related Profiles.

Cooper, Benjamin
Grinstaff, Mark

PMID: 30099277; PMCID: PMC6287749; DOI: 10.1016/j.biomaterials.2018.08.009;

Cooper BG, Catalina Bordeianu, Nazarian A, Snyder BD, Grinstaff MW. Active agents, biomaterials, and technologies to improve biolubrication and strengthen soft tissues. Biomaterials. 2018 10; 181:210-226.View Related Profiles.

Cooper, Benjamin
Grinstaff, Mark

PMID: 30092370; PMCID: PMC6766080; DOI: 10.1016/j.biomaterials.2018.07.040;

Reynolds DS, Bougher KM, Letendre JH, Fitzgerald SF, Gisladottir UO, Grinstaff MW, Zaman MH. Mechanical confinement via a PEG/Collagen interpenetrating network inhibits behavior characteristic of malignant cells in the triple negative breast cancer cell line MDA.MB.231. Acta Biomater. 2018 09 01; 77:85-95.View Related Profiles.

Grinstaff, Mark
Zaman, Muhammad

PMID: 30030173; PMCID: PMC6136430; DOI: 10.1016/j.actbio.2018.07.032;

Nickmanesh R, Stewart RC, Snyder BD, Grinstaff MW, Masri BA, Wilson DR. Contrast-enhanced computed tomography (CECT) attenuation is associated with stiffness of intact knee cartilage. J Orthop Res. 2018 10; 36(10):2641-2647. PMID: 29667235

Xiao R, Zeng J, Grinstaff MW. Biologically Active Branched Polysaccharide Mimetics: Synthesis via Ring-Opening Polymerization of a Maltose-Based ß-Lactam. ACS Macro Lett. 2018 Jul 17; 7(7):772-777. PMID: 35650766

Chapman Varela J, Sankar K, Hino A, Lin X, Chang WS, Coker D, Grinstaff M. Piperidinium ionic liquids as electrolyte solvents for sustained high temperature supercapacitor operation. Chem Commun (Camb). 2018 May 29; 54(44):5590-5593.View Related Profiles.

Coker, David
Grinstaff, Mark

PMID: 29766179

Ekladious I, Liu R, Varongchayakul N, Mejia Cruz LA, Todd DA, Zhang H, Oberlies NH, Padera RF, Colson YL, Grinstaff MW. Reinforcement of polymeric nanoassemblies for ultra-high drug loadings, modulation of stiffness and release kinetics, and sustained therapeutic efficacy. Nanoscale. 2018 May 10; 10(18):8360-8366. PMID: 29717728

Christadore L, Grinstaff MW, Schaus SE. Fluorescent Dendritic Micro-Hydrogels: Synthesis, Analysis and Use in Single-Cell Detection. Molecules. 2018 Apr 18; 23(4).View Related Profiles.

Grinstaff, Mark
Schaus, Scott

PMID: 29669998; PMCID: PMC6017717; DOI: 10.3390/molecules23040936;

Bhattarai A, Honkanen JTJ, Myller KAH, Prakash M, Korhonen M, Saukko AEA, Virén T, Joukainen A, Patwa AN, Kröger H, Grinstaff MW, Jurvelin JS, Töyräs J. Quantitative Dual Contrast CT Technique for Evaluation of Articular Cartilage Properties. Ann Biomed Eng. 2018 Jul; 46(7):1038-1046. PMID: 29654384

Nelson BB, Kawcak CE, Barrett MF, McIlwraith CW, Grinstaff MW, Goodrich LR. Recent advances in articular cartilage evaluation using computed tomography and magnetic resonance imaging. Equine Vet J. 2018 Sep; 50(5):564-579. PMID: 29344988

Lu C, Yang D, Sabbatini ME, Colby AH, Grinstaff MW, Oberlies NH, Pearce C, Liu K. Contrasting roles of H3K4me3 and H3K9me3 in regulation of apoptosis and gemcitabine resistance in human pancreatic cancer cells. BMC Cancer. 2018 02 06; 18(1):149.View Related Profiles.

Colby, Aaron
Grinstaff, Mark

PMID: 29409480; PMCID: PMC5801751; DOI: 10.1186/s12885-018-4061-y;

Varongchayakul N, Huttner D, Grinstaff MW, Meller A. Sensing Native Protein Solution Structures Using a Solid-state Nanopore: Unraveling the States of VEGF. Sci Rep. 2018 01 17; 8(1):1017. PMID: 29343861; PMCID: PMC5772516; DOI: 10.1038/s41598-018-19332-y;

Mäkelä JTA, Cooper BG, Korhonen RK, Grinstaff MW, Snyder BD. Functional effects of an interpenetrating polymer network on articular cartilage mechanical properties. Osteoarthritis Cartilage. 2018 03; 26(3):414-421.View Related Profiles.

Cooper, Benjamin
Grinstaff, Mark

PMID: 29326062

Wang J, Colson YL, Grinstaff MW. Tension-Activated Delivery of Small Molecules and Proteins from Superhydrophobic Composites. Adv Healthc Mater. 2018 04; 7(7):e1701096. PMID: 29280324; PMCID: PMC5968038; DOI: 10.1002/adhm.201701096;

Falde EJ, Wang J, Grinstaff MW. Surface Tension Sensor Meshes for Rapid Alcohol Quantification. RSC Adv. 2017; 7(78):49795-49798. PMID: 29276584; PMCID: PMC5736153; DOI: 10.1039/C7RA09320A;

Ekladious I, Liu R, Zhang H, Foil DH, Todd DA, Graf TN, Padera RF, Oberlies NH, Colson YL, Grinstaff MW. Synthesis of poly(1,2-glycerol carbonate)-paclitaxel conjugates and their utility as a single high-dose replacement for multi-dose treatment regimens in peritoneal cancer. Chem Sci. 2017 Dec 01; 8(12):8443-8450. PMID: 29619192; PMCID: PMC5863611; DOI: 10.1039/c7sc03501b;

Grinstaff MW, Kaplan HM, Kohn J. Predoctoral and Postdoctoral Training Pipeline in Translational Biomaterials Research and Regenerative Medicine. ACS Biomater Sci Eng. 2018 Dec 10; 4(12):3919-3926. PMID: 31106261; PMCID: PMC6521873; DOI: 10.1021/acsbiomaterials.7b00268;

Xiao R, Dane EL, Zeng J, McKnight CJ, Grinstaff MW. Synthesis of Altrose Poly-amido-saccharides with ß-N-(1?2)-d-amide Linkages: A Right-Handed Helical Conformation Engineered in at the Monomer Level. J Am Chem Soc. 2017 10 11; 139(40):14217-14223.View Related Profiles.

McKnight, C.
Grinstaff, Mark

PMID: 28902504

Morgan EF, Pittman J, DeGiacomo A, Cusher D, de Bakker CMJ, Mroszczyk KA, Grinstaff MW, Gerstenfeld LC. Erratum: "BMPR1A antagonist differentially affects cartilage and bone formation during fracture healing" [J Orthop Res. Vol 34, 2096-2105 (2016)]. J Orthop Res. 2018 03; 36(3):1040.View Related Profiles.

Morgan, Elise
Gerstenfeld, Louis
Grinstaff, Mark

PMID: 29623681

Reynolds DS, Tevis KM, Blessing WA, Colson YL, Zaman MH, Grinstaff MW. Breast Cancer Spheroids Reveal a Differential Cancer Stem Cell Response to Chemotherapeutic Treatment. Sci Rep. 2017 09 04; 7(1):10382.View Related Profiles.

Grinstaff, Mark
Zaman, Muhammad

PMID: 28871147; PMCID: PMC5583341; DOI: 10.1038/s41598-017-10863-4;

Tevis KM, Colson YL, Grinstaff MW. Embedded Spheroids as Models of the Cancer Microenvironment. Adv Biosyst. 2017 Oct; 1(10). PMID: 30221187; PMCID: PMC6135264; DOI: 10.1002/adbi.201700083;

Stewart RC, Patwa AN, Lusic H, Freedman JD, Wathier M, Snyder BD, Guermazi A, Grinstaff MW. Synthesis and Preclinical Characterization of a Cationic Iodinated Imaging Contrast Agent (CA4+) and Its Use for Quantitative Computed Tomography of Ex Vivo Human Hip Cartilage. J Med Chem. 2017 Jul 13; 60(13):5543-5555.View Related Profiles.

Guermazi, Ali
Freedman, Jonathan
Grinstaff, Mark

PMID: 28616978; PMCID: PMC6408935; DOI: 10.1021/acs.jmedchem.7b00234;

Mashiatulla M, Moran MM, Chan D, Li J, Freedman JD, Snyder BD, Grinstaff MW, Plaas A, Sumner DR. Murine articular cartilage morphology and compositional quantification with high resolution cationic contrast-enhanced µCT. J Orthop Res. 2017 12; 35(12):2740-2748.View Related Profiles.

Freedman, Jonathan
Grinstaff, Mark

PMID: 28471533; PMCID: PMC5671366; DOI: 10.1002/jor.23595;

Nelson BB, Goodrich LR, Barrett MF, Grinstaff MW, Kawcak CE. Use of contrast media in computed tomography and magnetic resonance imaging in horses: Techniques, adverse events and opportunities. Equine Vet J. 2017 Jul; 49(4):410-424. PMID: 28407291; DOI: 10.1111/evj.12689;

Jain A, Khalid M, Qureshi MM, Georgian-Smith D, Kaplan JA, Buch K, Grinstaff MW, Hirsch AE, Hines NL, Anderson SW, Gallagher KM, Bates DDB, Bloch BN. Stereotactic core needle breast biopsy marker migration: An analysis of factors contributing to immediate marker migration. Eur Radiol. 2017 Nov; 27(11):4797-4803.View Related Profiles.

Hirsch, Ariel
Bloch, Boris
Grinstaff, Mark
Qureshi, Muhammad
Anderson, Stephan

PMID: 28526892; DOI: 10.1007/s00330-017-4851-7;

Oh DJ, Lakin BA, Stewart RC, Wiewiorski M, Freedman JD, Grinstaff MW, Snyder BD. Contrast-enhanced CT imaging as a non-destructive tool for ex vivo examination of the biochemical content and structure of the human meniscus. J Orthop Res. 2017 May; 35(5):1018-1028.View Related Profiles.

Freedman, Jonathan
Grinstaff, Mark

PMID: 27302693; DOI: 10.1002/jor.23337;

Cooper BG, Lawson TB, Snyder BD, Grinstaff MW. Reinforcement of articular cartilage with a tissue-interpenetrating polymer network reduces friction and modulates interstitial fluid load support. Osteoarthritis Cartilage. 2017 Jul; 25(7):1143-1149.View Related Profiles.

Cooper, Benjamin
Grinstaff, Mark

PMID: 28285000; PMCID: PMC5726233; DOI: 10.1016/j.joca.2017.03.001;

Colby AH, Oberlies NH, Pearce CJ, Herrera VL, Colson YL, Grinstaff MW. Nanoparticle drug-delivery systems for peritoneal cancers: a case study of the design, characterization and development of the expansile nanoparticle. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2017 May; 9(3).View Related Profiles.

Colby, Aaron
Grinstaff, Mark
Herrera, Victoria

PMID: 28185434; PMCID: PMC5389910; DOI: 10.1002/wnan.1451;

Konieczynska MD, Grinstaff MW. On-Demand Dissolution of Chemically Cross-Linked Hydrogels. Acc Chem Res. 2017 02 21; 50(2):151-160. PMID: 28170219; PMCID: PMC5764157; DOI: 10.1021/acs.accounts.6b00547;

Lakin BA, Snyder BD, Grinstaff MW. Assessing Cartilage Biomechanical Properties: Techniques for Evaluating the Functional Performance of Cartilage in Health and Disease. Annu Rev Biomed Eng. 2017 Jun 21; 19:27-55. PMID: 28226218; DOI: 10.1146/annurev-bioeng-071516-044525;

Ramin MA, Sindhu KR, Appavoo A, Oumzil K, Grinstaff MW, Chassande O, Barthélémy P. Cation Tuning of Supramolecular Gel Properties: A New Paradigm for Sustained Drug Delivery. Adv Mater. 2017 Apr; 29(13). PMID: 28151562; DOI: 10.1002/adma.201605227;

Colby AH, Berry SM, Moran AM, Pasion KA, Liu R, Colson YL, Ruiz-Opazo N, Grinstaff MW, Herrera VL. Highly Specific and Sensitive Fluorescent Nanoprobes for Image-Guided Resection of Sub-Millimeter Peritoneal Tumors. ACS Nano. 2017 02 28; 11(2):1466-1477.View Related Profiles.

Colby, Aaron
Grinstaff, Mark
Ruiz-Opazo, Nelson
Herrera, Victoria

PMID: 28099801; PMCID: PMC5725964; DOI: 10.1021/acsnano.6b06777;

Konieczynska MD, Villa-Camacho JC, Ghobril C, Perez-Viloria M, Blessing WA, Nazarian A, Rodriguez EK, Grinstaff MW. A hydrogel sealant for the treatment of severe hepatic and aortic trauma with a dissolution feature for post-emergent care. Mater Horiz. 2017 Mar 01; 4(2):222-227. PMID: 28868146; PMCID: PMC5578431; DOI: 10.1039/C6MH00378H;

Tevis KM, Cecchi RJ, Colson YL, Grinstaff MW. Mimicking the tumor microenvironment to regulate macrophage phenotype and assessing chemotherapeutic efficacy in embedded cancer cell/macrophage spheroid models. Acta Biomater. 2017 Mar 01; 50:271-279. PMID: 28011141; PMCID: PMC5316313; DOI: 10.1016/j.actbio.2016.12.037;

Lin X, Chapman Varela J, Grinstaff MW. Synthesis of Ionic Liquid Based Electrolytes, Assembly of Li-ion Batteries, and Measurements of Performance at High Temperature. J Vis Exp. 2016 Dec 20; (118). PMID: 28060272; PMCID: PMC5226428; DOI: 10.3791/54864;

Wang J, Kaplan JA, Colson YL, Grinstaff MW. Mechanoresponsive materials for drug delivery: Harnessing forces for controlled release. Adv Drug Deliv Rev. 2017 Jan 01; 108:68-82. PMID: 27856307; PMCID: PMC5285479; DOI: 10.1016/j.addr.2016.11.001;

Lin X, Salari M, Arava LM, Ajayan PM, Grinstaff MW. High temperature electrical energy storage: advances, challenges, and frontiers. Chem Soc Rev. 2016 Oct 24; 45(21):5848-5887. PMID: 27775120

Stewart RC, Honkanen JTJ, Kokkonen HT, Tiitu V, Saarakkala S, Joukainen A, Snyder BD, Jurvelin JS, Grinstaff MW, Töyräs J. Contrast-Enhanced Computed Tomography Enables Quantitative Evaluation of Tissue Properties at Intrajoint Regions in Cadaveric Knee Cartilage. Cartilage. 2017 Oct; 8(4):391-399. PMID: 28934883; PMCID: PMC5613888; DOI: 10.1177/1947603516665443;

Konieczynska MD, Villa-Camacho JC, Ghobril C, Perez-Viloria M, Tevis KM, Blessing WA, Nazarian A, Rodriguez EK, Grinstaff MW. On-Demand Dissolution of a Dendritic Hydrogel-based Dressing for Second-Degree Burn Wounds through Thiol-Thioester Exchange Reaction. Angew Chem Int Ed Engl. 2016 08 16; 55(34):9984-7. PMID: 27410669; PMCID: PMC5168721; DOI: 10.1002/anie.201604827;

Falde EJ, Yohe ST, Colson YL, Grinstaff MW. Superhydrophobic materials for biomedical applications. Biomaterials. 2016 10; 104:87-103. PMID: 27449946; PMCID: PMC5136454; DOI: 10.1016/j.biomaterials.2016.06.050;

Trudeau KM, Colby AH, Zeng J, Las G, Feng JH, Grinstaff MW, Shirihai OS. Lysosome acidification by photoactivated nanoparticles restores autophagy under lipotoxicity. J Cell Biol. 2016 Jul 04; 214(1):25-34.View Related Profiles.

Colby, Aaron
Las, Guy
Trudeau, Kyle
Grinstaff, Mark
Shirihai, Orian

PMID: 27377248; PMCID: PMC4932370; DOI: 10.1083/jcb.201511042;

Liu R, Colby AH, Gilmore D, Schulz M, Zeng J, Padera RF, Shirihai O, Grinstaff MW, Colson YL. Nanoparticle tumor localization, disruption of autophagosomal trafficking, and prolonged drug delivery improve survival in peritoneal mesothelioma. Biomaterials. 2016 Sep; 102:175-86.View Related Profiles.

Colby, Aaron
Grinstaff, Mark
Shirihai, Orian

PMID: 27343465; PMCID: PMC4948582; DOI: 10.1016/j.biomaterials.2016.06.031;

Ababtain K, Babu G, Lin X, Rodrigues MT, Gullapalli H, Ajayan PM, Grinstaff MW, Arava LM. Ionic Liquid-Organic Carbonate Electrolyte Blends To Stabilize Silicon Electrodes for Extending Lithium Ion Battery Operability to 100 °C. ACS Appl Mater Interfaces. 2016 Jun 22; 8(24):15242-9. PMID: 27237138; DOI: 10.1021/acsami.6b02620;

Chin SL, Lu Q, Dane EL, Dominguez L, McKnight CJ, Straub JE, Grinstaff MW. Combined Molecular Dynamics Simulations and Experimental Studies of the Structure and Dynamics of Poly-Amido-Saccharides. J Am Chem Soc. 2016 05 25; 138(20):6532-40.View Related Profiles.

McKnight, C.
Straub, John
Grinstaff, Mark

PMID: 27119983; DOI: 10.1021/jacs.6b01837;

Digesu CS, Hofferberth SC, Grinstaff MW, Colson YL. From Diagnosis to Treatment: Clinical Applications of Nanotechnology in Thoracic Surgery. Thorac Surg Clin. 2016 May; 26(2):215-28.View Related Profiles.

Digesu, Christopher
Grinstaff, Mark

PMID: 27112260; PMCID: PMC4851727; DOI: 10.1016/j.thorsurg.2015.12.009;

Honkanen JT, Turunen MJ, Freedman JD, Saarakkala S, Grinstaff MW, Ylärinne JH, Jurvelin JS, Töyräs J. Cationic Contrast Agent Diffusion Differs Between Cartilage and Meniscus. Ann Biomed Eng. 2016 Oct; 44(10):2913-21.View Related Profiles.

Freedman, Jonathan
Grinstaff, Mark

PMID: 27129372; PMCID: PMC5042996; DOI: 10.1007/s10439-016-1629-z;

Herrera VL, Colby AH, Tan GA, Moran AM, O'Brien MJ, Colson YL, Ruiz-Opazo N, Grinstaff MW. Evaluation of expansile nanoparticle tumor localization and efficacy in a cancer stem cell-derived model of pancreatic peritoneal carcinomatosis. Nanomedicine (Lond). 2016 May; 11(9):1001-15.View Related Profiles.

Colby, Aaron
Grinstaff, Mark
O'Brien, Michael
Ruiz-Opazo, Nelson
Herrera, Victoria

PMID: 27078118; PMCID: PMC4910944; DOI: 10.2217/nnm-2015-0023;

Morgan EF, Pittman J, DeGiacomo A, Cusher D, de Bakker CM, Mroszczyk KA, Grinstaff MW, Gerstenfeld LC. BMPR1A antagonist differentially affects cartilage and bone formation during fracture healing. J Orthop Res. 2016 Dec; 34(12):2096-2105.View Related Profiles.

Morgan, Elise
Gerstenfeld, Louis
Grinstaff, Mark

PMID: 26990682; DOI: 10.1002/jor.23233;

Kaplan JA, Barthélémy P, Grinstaff MW. Self-assembled nanofiber hydrogels for mechanoresponsive therapeutic anti-TNFa antibody delivery. Chem Commun (Camb). 2016 Apr 30; 52(34):5860-3. PMID: 27049283; DOI: 10.1039/c6cc02221a;

Ghobril C, Rodriguez EK, Nazarian A, Grinstaff MW. Recent Advances in Dendritic Macromonomers for Hydrogel Formation and Their Medical Applications. Biomacromolecules. 2016 Apr 11; 17(4):1235-52. PMID: 26978246; DOI: 10.1021/acs.biomac.6b00004;

Sun Y, Kaplan JA, Shieh A, Sun HL, Croce CM, Grinstaff MW, Parquette JR. Self-assembly of a 5-fluorouracil-dipeptide hydrogel. Chem Commun (Camb). 2016 Apr 18; 52(30):5254-7. PMID: 26996124; DOI: 10.1039/c6cc01195k;

Cooper BG, Stewart RC, Burstein D, Snyder BD, Grinstaff MW. A Tissue-Penetrating Double Network Restores the Mechanical Properties of Degenerated Articular Cartilage. Angew Chem Int Ed Engl. 2016 Mar 18; 55(13):4226-30.View Related Profiles.

Cooper, Benjamin
Grinstaff, Mark

PMID: 26934682; PMCID: PMC5726259; DOI: 10.1002/anie.201511767;

Hersey JS, LaManna CM, Lusic H, Grinstaff MW. Stimuli responsive charge-switchable lipids: Capture and release of nucleic acids. Chem Phys Lipids. 2016 Mar; 196:52-60. PMID: 26896839; PMCID: PMC4899981; DOI: 10.1016/j.chemphyslip.2016.02.005;

Hofferberth SC, Grinstaff MW, Colson YL. Nanotechnology applications in thoracic surgery. Eur J Cardiothorac Surg. 2016 Jul; 50(1):6-16. PMID: 26843431; PMCID: PMC4913874; DOI: 10.1093/ejcts/ezw002;

Ricapito NG, Ghobril C, Zhang H, Grinstaff MW, Putnam D. Synthetic Biomaterials from Metabolically Derived Synthons. Chem Rev. 2016 Feb 24; 116(4):2664-704. PMID: 26821863; PMCID: PMC5810137; DOI: 10.1021/acs.chemrev.5b00465;

Wang J, Kaplan JA, Colson YL, Grinstaff MW. Stretch-Induced Drug Delivery from Superhydrophobic Polymer Composites: Use of Crack Propagation Failure Modes for Controlling Release Rates. Angew Chem Int Ed Engl. 2016 Feb 18; 55(8):2796-800. PMID: 26804182; PMCID: PMC4899983; DOI: 10.1002/anie.201511052;

Colby AH, Liu R, Schulz MD, Padera RF, Colson YL, Grinstaff MW. Two-Step Delivery: Exploiting the Partition Coefficient Concept to Increase Intratumoral Paclitaxel Concentrations In vivo Using Responsive Nanoparticles. Sci Rep. 2016 Jan 07; 6:18720.View Related Profiles.

Colby, Aaron
Grinstaff, Mark

PMID: 26740245; PMCID: PMC4703988; DOI: 10.1038/srep18720;

Lakin BA, Patel H, Holland C, Freedman JD, Shelofsky JS, Snyder BD, Stok KS, Grinstaff MW. Contrast-enhanced CT using a cationic contrast agent enables non-destructive assessment of the biochemical and biomechanical properties of mouse tibial plateau cartilage. J Orthop Res. 2016 Jul; 34(7):1130-8.View Related Profiles.

Freedman, Jonathan
Grinstaff, Mark

PMID: 26697956; PMCID: PMC5556386; DOI: 10.1002/jor.23141;

Hersey JS, Meller A, Grinstaff MW. Functionalized Nanofiber Meshes Enhance Immunosorbent Assays. Anal Chem. 2015 Dec 1; 87(23):11863-70. PMID: 26551162; PMCID: PMC5136455; DOI: 10.1021/acs.analchem.5b03386;

Kaplan JA, Liu R, Freedman JD, Padera R, Schwartz J, Colson YL, Grinstaff MW. Prevention of lung cancer recurrence using cisplatin-loaded superhydrophobic nanofiber meshes. Biomaterials. 2016 Jan; 76:273-81.View Related Profiles.

Freedman, Jonathan
Grinstaff, Mark

PMID: 26547283; PMCID: PMC4790118; DOI: 10.1016/j.biomaterials.2015.10.060;

Zhang H, Lin X, Chin S, Grinstaff MW. Synthesis and Characterization of Poly(glyceric Acid Carbonate): A Degradable Analogue of Poly(acrylic Acid). J Am Chem Soc. 2015 Oct 7; 137(39):12660-6. PMID: 26378624; DOI: 10.1021/jacs.5b07911;

Kaplan J, Grinstaff M. Fabricating Superhydrophobic Polymeric Materials for Biomedical Applications. J Vis Exp. 2015; (102):e53117. PMID: 26383018; PMCID: PMC4692566; DOI: 10.3791/53117;

Lin X, Kavian R, Lu Y, Hu Q, Shao-Horn Y, Grinstaff MW. Thermally-responsive, nonflammable phosphonium ionic liquid electrolytes for lithium metal batteries: operating at 100 degrees celsius. Chem Sci. 2015 Nov 13; 6(11):6601-6606. PMID: 28757963; PMCID: PMC5506629; DOI: 10.1039/c5sc01518a;

Hersey JS, Yohe ST, Grinstaff MW. Poly(e-caprolactone) Microfiber Meshes for Repeated Oil Retrieval. Environ Sci (Camb). 2015 Nov 01; 1(6):779-786. PMID: 26989490; PMCID: PMC4790115; DOI: 10.1039/C5EW00107B;

Falde EJ, Yohe ST, Grinstaff MW. Sensors: Surface Tension Triggered Wetting and Point of Care Sensor Design (Adv. Healthcare Mater. 11/2015). Adv Healthc Mater. 2015 Aug; 4(11):1653. PMID: 26250953; DOI: 10.1002/adhm.201570066;

Falde EJ, Freedman JD, Herrera VL, Yohe ST, Colson YL, Grinstaff MW. Layered superhydrophobic meshes for controlled drug release. J Control Release. 2015 Sep 28; 214:23-9.View Related Profiles.

Freedman, Jonathan
Grinstaff, Mark
Herrera, Victoria

PMID: 26160309; PMCID: PMC4841832; DOI: 10.1016/j.jconrel.2015.06.042;

Freedman JD, Lusic H, Wiewiorski M, Farley M, Snyder BD, Grinstaff MW. A cationic gadolinium contrast agent for magnetic resonance imaging of cartilage. Chem Commun (Camb). 2015 Jun 30; 51(56):11166-9.View Related Profiles.

Freedman, Jonathan
Grinstaff, Mark

PMID: 26051807; PMCID: PMC4841792; DOI: 10.1039/c5cc03354c;

Falde EJ, Yohe ST, Grinstaff MW. Surface Tension Triggered Wetting and Point of Care Sensor Design. Adv Healthc Mater. 2015 Aug 5; 4(11):1654-7. PMID: 26097150; PMCID: PMC4790105; DOI: 10.1002/adhm.201500276;

Stolzoff M, Ekladious I, Colby AH, Colson YL, Porter TM, Grinstaff MW. Synthesis and Characterization of Hybrid Polymer/Lipid Expansile Nanoparticles: Imparting Surface Functionality for Targeting and Stability. Biomacromolecules. 2015 Jul 13; 16(7):1958-66.View Related Profiles.

Colby, Aaron
Grinstaff, Mark
Porter, Tyrone

PMID: 26053219; DOI: 10.1021/acs.biomac.5b00336;

Kaplan JA, Grinstaff MW, Bloch BN. Polymer film-nanoparticle composites as new multimodality, non-migrating breast biopsy markers. Eur Radiol. 2016 Mar; 26(3):866-73.View Related Profiles.

Bloch, Boris
Grinstaff, Mark

PMID: 26060064; DOI: 10.1007/s00330-015-3852-7;

Lakin BA, Ellis DJ, Shelofsky JS, Freedman JD, Grinstaff MW, Snyder BD. Contrast-enhanced CT facilitates rapid, non-destructive assessment of cartilage and bone properties of the human metacarpal. Osteoarthritis Cartilage. 2015 Dec; 23(12):2158-66.View Related Profiles.

Freedman, Jonathan
Grinstaff, Mark

PMID: 26067518; PMCID: PMC4841831; DOI: 10.1016/j.joca.2015.05.033;

Villa-Camacho JC, Ghobril C, Anez-Bustillos L, Grinstaff MW, Rodríguez EK, Nazarian A. The efficacy of a lysine-based dendritic hydrogel does not differ from those of commercially available tissue sealants and adhesives: an ex vivo study. BMC Musculoskelet Disord. 2015; 16:116. PMID: 25968126; PMCID: PMC4445931; DOI: 10.1186/s12891-015-0573-7;

Konieczynska MD, Lin X, Zhang H, Grinstaff MW. Synthesis of Aliphatic Poly(ether 1,2-glycerol carbonate)s via Copolymerization of CO2 with Glycidyl Ethers Using a Cobalt Salen Catalyst and Study of a Thermally Stable Solid Polymer Electrolyte. ACS Macro Lett. 2015 May 19; 4(5):533-537. PMID: 35596282

Lei H, Hofferberth SC, Liu R, Colby A, Tevis KM, Catalano P, Grinstaff MW, Colson YL. Paclitaxel-loaded expansile nanoparticles enhance chemotherapeutic drug delivery in mesothelioma 3-dimensional multicellular spheroids. J Thorac Cardiovasc Surg. 2015 May; 149(5):1417-24; discussion 1424-25.e1.View Related Profiles.

Colby, Aaron
Grinstaff, Mark

PMID: 25841659; DOI: 10.1016/j.jtcvs.2015.02.020;

Ghobril C, Grinstaff MW. The chemistry and engineering of polymeric hydrogel adhesives for wound closure: a tutorial. Chem Soc Rev. 2015 Apr 7; 44(7):1820-35. PMID: 25649260; DOI: 10.1039/c4cs00332b;

Kim SH, Kaplan JA, Sun Y, Shieh A, Sun HL, Croce CM, Grinstaff MW, Parquette JR. The self-assembly of anticancer camptothecin-dipeptide nanotubes: a minimalistic and high drug loading approach to increased efficacy. Chemistry. 2015 Jan 2; 21(1):101-5. PMID: 25384556; DOI: 10.1002/chem.201404520;

Zhang H, Grinstaff MW. Macromol. Rapid commun. 22/2014. Macromol Rapid Commun. 2014 Nov; 35(22):1901. PMID: 25401933; DOI: 10.1002/marc.201470079;

Zhang H, Grinstaff MW. Recent advances in glycerol polymers: chemistry and biomedical applications. Macromol Rapid Commun. 2014 Nov; 35(22):1906-24. PMID: 25308354; PMCID: PMC4415886; DOI: 10.1002/marc.201400389;

Yonekura R, Grinstaff MW. The effects of counterion composition on the rheological and conductive properties of mono- and diphosphonium ionic liquids. Phys Chem Chem Phys. 2014 Oct 14; 16(38):20608-17. PMID: 25155840; DOI: 10.1039/c4cp02594f;

Freedman JD, Lusic H, Snyder BD, Grinstaff MW. Tantalum oxide nanoparticles for the imaging of articular cartilage using X-ray computed tomography: visualization of ex vivo/in vivo murine tibia and ex vivo human index finger cartilage. Angew Chem Int Ed Engl. 2014 Aug 4; 53(32):8406-10.View Related Profiles.

Freedman, Jonathan
Grinstaff, Mark

PMID: 24981730; PMCID: PMC4303344; DOI: 10.1002/anie.201404519;

Stidham SE, Chin SL, Dane EL, Grinstaff MW. Carboxylated glucuronic poly-amido-saccharides as protein stabilizing agents. J Am Chem Soc. 2014 Jul 9; 136(27):9544-7. PMID: 24949521; PMCID: PMC4105061; DOI: 10.1021/ja5036804;

Entezari V, Bansal PN, Stewart RC, Lakin BA, Grinstaff MW, Snyder BD. Effect of mechanical convection on the partitioning of an anionic iodinated contrast agent in intact patellar cartilage. J Orthop Res. 2014 Oct; 32(10):1333-40. PMID: 24961833; DOI: 10.1002/jor.22662;

Entezari V, Bansal PN, Stewart RC, Lakin BA, Grinstaff MW, Snyder BD. Effect of Mechanical Convection on the Partitioning of an Anionic Iodinated Contrast Agent in Intact Patellar Cartilage. Journal of Orthopaedic Research. 2014; 32(10):1333–1340. View Publication

Kaplan JA, Lei H, Liu R, Padera R, Colson YL, Grinstaff MW. Imparting superhydrophobicity to biodegradable poly(lactide-co-glycolide) electrospun meshes. Biomacromolecules. 2014 Jul 14; 15(7):2548-54. PMID: 24901038; PMCID: PMC4215912; DOI: 10.1021/bm500410h;

Hersey JS, Freedman JD, Grinstaff MW. Photoactive Electrospun Polymeric Meshes: Spatiotemporally Wetting of Textured 3-Dimensional Structures. J Mater Chem B. 2014 May 28; 2(20):2974-2977.View Related Profiles.

Freedman, Jonathan
Grinstaff, Mark

PMID: 24921050; PMCID: PMC4048670; DOI: 10.1039/C4TB00143E;

Ghobril C, Heinrich B, Dane EL, Grinstaff MW. Synthesis of Hydrophobic Carbohydrate Polymers and Their Formation of Thermotropic Liquid Crystalline Phases. ACS Macro Lett. 2014 Apr 15; 3(4):359-363. PMID: 24804154; PMCID: PMC3999795; DOI: 10.1021/mz5000703;

Dane EL, Ballok AE, O'Toole GA, Grinstaff MW. Synthesis of Bioinspired Carbohydrate Amphiphiles that Promote and Inhibit Biofilms. Chem Sci. 2014 Feb 01; 5(2). PMID: 24376911; PMCID: PMC3873002; DOI: 10.1039/C3SC52777H;

Charoen KM, Fallica B, Colson YL, Zaman MH, Grinstaff MW. Embedded multicellular spheroids as a biomimetic 3D cancer model for evaluating drug and drug-device combinations. Biomaterials. 2014 Feb; 35(7):2264-71.View Related Profiles.

Grinstaff, Mark
Zaman, Muhammad

PMID: 24360576; PMCID: PMC3923358; DOI: 10.1016/j.biomaterials.2013.11.038;

Ghobril C, Charoen K, Rodriguez EK, Nazarian A, Grinstaff MW. A dendritic thioester hydrogel based on thiol-thioester exchange as a dissolvable sealant system for wound closure. Angew Chem Int Ed Engl. 2013 Dec 23; 52(52):14070-4. PMID: 24282150; PMCID: PMC4000691; DOI: 10.1002/anie.201308007;

Squires AH, Hersey JS, Grinstaff MW, Meller A. A nanopore-nanofiber mesh biosensor to control DNA translocation. J Am Chem Soc. 2013 Nov 6; 135(44):16304-7. PMID: 24143914; PMCID: PMC4039743; DOI: 10.1021/ja408685x;

Eldridge J, Colby AH, Willmott G, Yu S, Grinstaff MW. Use of Tunable Pores for Accurate Characterization of Micro- and Nano- Particle Systems in Nanomedicine. Selected Topics in Nanomedicine. 2013; 3:219-256. View Publication

Dane EL, Chin SL, Grinstaff MW. Synthetic Enantiopure Carbohydrate Polymers that are Highly Soluble in Water and Noncytotoxic. ACS Macro Lett. 2013 Oct 15; 2(10):887-890. PMID: 24575361; PMCID: PMC3932237; DOI: 10.1021/mz400394r;

Zhang H, Grinstaff MW. Terpolymerization of Benzyl Glycidyl Ether, Propylene Oxide and CO2 Using Binary and Bifunctional [rac-SalcyCoIIIX] Complexes and the Thermal and Mechanical Properties of the Resultant Poly(benzyl 1,2-glycerol-co-propylene carbonate)s and Poly(1,2-glycerol-co-propylene carbonate)s (invited manuscript). Journal of Applied Polymer Science. 2013; 131:39893. View Publication

Kuo W, Nimeskern L, Martínez Ávila H, Hofmann S, Freedman J, Grinstaff MW, Müller R, Stok KS. Developing staining protocols for visualization of tissue-engineering scaffolds using micro computed tomography in native wet state. Biomed Tech (Berl). 2013 08; 58 Suppl 1. PMID: 24042942; PMCID: PMC4641043; DOI: 10.1515/bmt-2013-4273;

Yadav V, Freedman JD, Grinstaff M, Sen A. Bone-crack detection, targeting, and repair using ion gradients. Angew Chem Int Ed Engl. 2013 Oct 11; 52(42):10997-1001.View Related Profiles.

Freedman, Jonathan
Grinstaff, Mark

PMID: 24039057; PMCID: PMC4640360; DOI: 10.1002/anie.201305759;

Yohe ST, Freedman JD, Falde EJ, Colson YL, Grinstaff MW. A Mechanistic Study of Wetting Superhydrophobic Porous 3D Meshes. Adv Funct Mater. 2013 Aug 07; 23(29):3628-3637.View Related Profiles.

Freedman, Jonathan
Grinstaff, Mark

PMID: 25309305; PMCID: PMC4191864; DOI: 10.1002/adfm.201203111;

Lakin BA, Grasso DJ, Stewart RC, Freedman JD, Snyder BD, Grinstaff MW. Contrast enhanced CT attenuation correlates with the GAG content of bovine meniscus. J Orthop Res. 2013 Nov; 31(11):1765-71.View Related Profiles.

Freedman, Jonathan
Grinstaff, Mark

PMID: 23832854; PMCID: PMC3931129; DOI: 10.1002/jor.22421;

Lin X, Grinstaff MW. Ionic Supramolecular Assemblies (invited manuscript). Israel Journal of Chemistry. 2013; 53:498-510. View Publication
Chen F, Clough A, Reinhard B, Grinstaff MW, Jiang N, Koga T, Tsui OKC. Glass Transition Temperature of Polymer-Nanoparticle Composites: Effect of Polymer-Particle Interfacial Energy. Macromolecules. 2013; 46:4663-4669. View Publication

Zubris KA, Liu R, Colby A, Schulz MD, Colson YL, Grinstaff MW. In vitro activity of Paclitaxel-loaded polymeric expansile nanoparticles in breast cancer cells. Biomacromolecules. 2013 Jun 10; 14(6):2074-82.View Related Profiles.

Colby, Aaron
Grinstaff, Mark

PMID: 23617223; PMCID: PMC3915286; DOI: 10.1021/bm400434h;

Zhang XX, Lamanna CM, Kohman RE, McIntosh TJ, Han X, Grinstaff MW. Lipid-mediated DNA and siRNA Transfection Efficiency Depends on Peptide Headgroup. Soft Matter. 2013 May 05; 9(17).View Related Profiles.

Grinstaff, Mark
Kohman, Richard
Han, Xue

PMID: 24391676; PMCID: PMC3878819; DOI: 10.1039/C3SM27633C;

Zhang H, Grinstaff MW. Synthesis of atactic and isotactic poly(1,2-glycerol carbonate)s: degradable polymers for biomedical and pharmaceutical applications. J Am Chem Soc. 2013 May 8; 135(18):6806-9. PMID: 23611027; DOI: 10.1021/ja402558m;

Yohe ST, Kopechek JA, Porter TM, Colson YL, Grinstaff MW. Triggered drug release from superhydrophobic meshes using high-intensity focused ultrasound. Adv Healthc Mater. 2013 Sep; 2(9):1204-8.View Related Profiles.

Grinstaff, Mark
Porter, Tyrone

PMID: 23592698; PMCID: PMC3923359; DOI: 10.1002/adhm.201200381;

Wathier M, Lakin BA, Bansal PN, Stoddart SS, Snyder BD, Grinstaff MW. A large-molecular-weight polyanion, synthesized via ring-opening metathesis polymerization, as a lubricant for human articular cartilage. J Am Chem Soc. 2013 Apr 3; 135(13):4930-3. PMID: 23496043; DOI: 10.1021/ja400695h;

Colby AH, Colson YL, Grinstaff MW. Microscopy and tunable resistive pulse sensing characterization of the swelling of pH-responsive, polymeric expansile nanoparticles. Nanoscale. 2013 Apr 21; 5(8):3496-504.View Related Profiles.

Colby, Aaron
Grinstaff, Mark

PMID: 23487041; PMCID: PMC3878811; DOI: 10.1039/c3nr00114h;

Yohe ST, Grinstaff MW. A facile approach to robust superhydrophobic 3D coatings via connective-particle formation using the electrospraying process. Chem Commun (Camb). 2013 Jan 28; 49(8):804-6. PMID: 23235806; PMCID: PMC3878809; DOI: 10.1039/c2cc38012a;

Stidham SE, Weinberg BH, Grinstaff MW. Characterization of Large Molecular Weight Acid-Functionalized Norbornene and Hydroxylated Norbornane Polymers Prepared by Ring-Opening Metathesis Polymerization. Journal of Polymer Science Part A: Polymer Chemistry. 2012; 50:5185–5190. View Publication

Liu R, Gilmore DM, Zubris KA, Xu X, Catalano PJ, Padera RF, Grinstaff MW, Colson YL. Prevention of nodal metastases in breast cancer following the lymphatic migration of paclitaxel-loaded expansile nanoparticles. Biomaterials. 2013 Feb; 34(7):1810-9. PMID: 23228419; PMCID: PMC3541056; DOI: 10.1016/j.biomaterials.2012.11.038;

Lusic H, Grinstaff MW. X-ray-computed tomography contrast agents. Chem Rev. 2013 Mar 13; 113(3):1641-66. PMID: 23210836; PMCID: PMC3878741; DOI: 10.1021/cr200358s;

Stewart RC, Bansal PN, Entezari V, Lusic H, Nazarian RM, Snyder BD, Grinstaff MW. Contrast-enhanced CT with a high-affinity cationic contrast agent for imaging ex vivo bovine, intact ex vivo rabbit, and in vivo rabbit cartilage. Radiology. 2013 Jan; 266(1):141-50. PMID: 23192774; PMCID: PMC3528972; DOI: 10.1148/radiol.12112246;

Lin X, Navailles L, Nallet F, Grinstaff MW. Influence of Phosphonium Alkyl Substituents on the Rheological and Thermal Properties of Phosphonium-PAA Based Supramolecular Polymeric Assemblies. Macromolecules. 2012; 45:9500–9506. View Publication

Hayward LN, de Bakker CM, Gerstenfeld LC, Grinstaff MW, Morgan EF. Assessment of contrast-enhanced computed tomography for imaging of cartilage during fracture healing. J Orthop Res. 2013 Apr; 31(4):567-73.View Related Profiles.

Morgan, Elise
Gerstenfeld, Louis
Grinstaff, Mark

PMID: 23165442; PMCID: PMC3761062; DOI: 10.1002/jor.22265;

Gilmore D, Schulz M, Liu R, Zubris KA, Padera RF, Catalano PJ, Grinstaff MW, Colson YL. Cytoreductive surgery and intraoperative administration of paclitaxel-loaded expansile nanoparticles delay tumor recurrence in ovarian carcinoma. Ann Surg Oncol. 2013 May; 20(5):1684-93. PMID: 23128939; DOI: 10.1245/s10434-012-2696-5;

Lakin BA, Grasso DJ, Shah SS, Stewart RC, Bansal PN, Freedman JD, Grinstaff MW, Snyder BD. Cationic agent contrast-enhanced computed tomography imaging of cartilage correlates with the compressive modulus and coefficient of friction. Osteoarthritis Cartilage. 2013 Jan; 21(1):60-8.View Related Profiles.

Freedman, Jonathan
Grinstaff, Mark

PMID: 23041438; PMCID: PMC3878721; DOI: 10.1016/j.joca.2012.09.007;

Dane EL, Grinstaff MW. Poly-amido-saccharides: synthesis via anionic polymerization of a ß-lactam sugar monomer. J Am Chem Soc. 2012 Oct 3; 134(39):16255-64. PMID: 22937875; PMCID: PMC3684047; DOI: 10.1021/ja305900r;

Colson YL, Grinstaff MW. Biologically responsive polymeric nanoparticles for drug delivery. Adv Mater. 2012 Jul 24; 24(28):3878-86. PMID: 22988558

O'Toole GA, Wathier M, Zegans ME, Shanks RM, Kowalski R, Grinstaff MW. Diphosphonium ionic liquids as broad-spectrum antimicrobial agents. Cornea. 2012 Jul; 31(7):810-6. PMID: 22236790; PMCID: PMC3336019; DOI: 10.1097/ICO.0b013e31823f0a86;

Yohe ST, Herrera VL, Colson YL, Grinstaff MW. 3D superhydrophobic electrospun meshes as reinforcement materials for sustained local drug delivery against colorectal cancer cells. J Control Release. 2012 Aug 20; 162(1):92-101.View Related Profiles.

Grinstaff, Mark
Herrera, Victoria

PMID: 22684120; PMCID: PMC3878861; DOI: 10.1016/j.jconrel.2012.05.047;

Taib N, Aimé A, Moreau L, Camplo M, Houmadi S, Desbat B, Laguerre M, Grinstaff MW, Bestel I, Barthélémy P. Formation of supramolecular systems via directed Nucleoside-Lipid recognition. J Colloid Interface Sci. 2012 Jul 1; 377(1):122-30. PMID: 22487235; DOI: 10.1016/j.jcis.2012.03.041;

LaManna CM, Lusic H, Camplo M, McIntosh TJ, Barthélémy P, Grinstaff MW. Charge-reversal lipids, peptide-based lipids, and nucleoside-based lipids for gene delivery. Acc Chem Res. 2012 Jul 17; 45(7):1026-38. PMID: 22439686; PMCID: PMC3878820; DOI: 10.1021/ar200228y;

LaManna CM, Grinstaff MW. The Role of Supramolecular Chemistry in Responsive Vectors for Gene Delivery. Supramolecular Chemistry: From Molecules to Nanomaterials. 2012; 1807-1823. View Publication

Godeau G, Navailles L, Nallet F, Lin X, McIntosh TJ, Grinstaff MW. From Brittle to Pliant Viscoelastic Materials with Solid State Linear Polyphosphonium - Carboxylate Assemblies. Macromolecules. 2012 Mar 13; 45(5):2509-2513. PMID: 24511156; PMCID: PMC3915284; DOI: 10.1021/ma3002092;

Wolinsky JB, Yohe ST, Colson YL, Grinstaff MW. Functionalized hydrophobic poly(glycerol-co-e-caprolactone) depots for controlled drug release. Biomacromolecules. 2012 Feb 13; 13(2):406-11. PMID: 22242897; PMCID: PMC3878815; DOI: 10.1021/bm201443m;

Yohe ST, Colson YL, Grinstaff MW. Superhydrophobic materials for tunable drug release: using displacement of air to control delivery rates. J Am Chem Soc. 2012 Feb 1; 134(4):2016-9. PMID: 22279966; PMCID: PMC3878812; DOI: 10.1021/ja211148a;

Khullar OV, Griset AP, Gibbs-Strauss SL, Chirieac LR, Zubris KA, Frangioni JV, Grinstaff MW, Colson YL. Nanoparticle migration and delivery of Paclitaxel to regional lymph nodes in a large animal model. J Am Coll Surg. 2012 Mar; 214(3):328-37. PMID: 22225645; PMCID: PMC3288886; DOI: 10.1016/j.jamcollsurg.2011.11.006;

Mintzer MA, Dane EL, O'Toole GA, Grinstaff MW. Exploiting dendrimer multivalency to combat emerging and re-emerging infectious diseases. Mol Pharm. 2012 Mar 5; 9(3):342-54. PMID: 22126461; PMCID: PMC3729585; DOI: 10.1021/mp2005033;

Wolinsky JB, Colson YL, Grinstaff MW. Local drug delivery strategies for cancer treatment: gels, nanoparticles, polymeric films, rods, and wafers. J Control Release. 2012 Apr 10; 159(1):14-26. PMID: 22154931; PMCID: PMC3878823; DOI: 10.1016/j.jconrel.2011.11.031;

Zubris KA, Colson YL, Grinstaff MW. Hydrogels as intracellular depots for drug delivery. Mol Pharm. 2012 Jan 1; 9(1):196-200. PMID: 22053709; DOI: 10.1021/mp200367s;

Hayward LN, de Bakker CM, Lusic H, Gerstenfeld LC, Grinstaff MW, Morgan EF. MRT letter: Contrast-enhanced computed tomographic imaging of soft callus formation in fracture healing. Microsc Res Tech. 2012 Jan; 75(1):7-14.View Related Profiles.

Morgan, Elise
Gerstenfeld, Louis
Grinstaff, Mark

PMID: 22038692; PMCID: PMC3380422; DOI: 10.1002/jemt.21100;

Meyers SR, Grinstaff MW. Biocompatible and bioactive surface modifications for prolonged in vivo efficacy. Chem Rev. 2012 Mar 14; 112(3):1615-32. PMID: 22007787; PMCID: PMC3878818; DOI: 10.1021/cr2000916;

Roberts GS, Yu S, Zeng Q, Chan LC, Anderson W, Colby AH, Grinstaff MW, Reid S, Vogel R. Tunable pores for measuring concentrations of synthetic and biological nanoparticle dispersions. Biosens Bioelectron. 2012 Jan 15; 31(1):17-25.View Related Profiles.

Colby, Aaron
Grinstaff, Mark

PMID: 22019099; DOI: 10.1016/j.bios.2011.09.040;

Schulz MD, Zubris KA, Wade JE, Padera RF, Xu X, Grinstaff MW, Colson YL. Paclitaxel-loaded expansile nanoparticles in a multimodal treatment model of malignant mesothelioma. Ann Thorac Surg. 2011 Dec; 92(6):2007-13; discussion 2013-4. PMID: 21963198; DOI: 10.1016/j.athoracsur.2011.04.106;

Oelker AM, Grinstaff MW. Synthesis, characterization, and in vitro evaluation of a hydrogel-based corneal onlay. IEEE Trans Nanobioscience. 2012 Mar; 11(1):37-45. PMID: 21908258; DOI: 10.1109/TNB.2011.2166978;

Liu R, Wolinsky JB, Catalano PJ, Chirieac LR, Wagner AJ, Grinstaff MW, Colson YL, Raut CP. Paclitaxel-eluting polymer film reduces locoregional recurrence and improves survival in a recurrent sarcoma model: a novel investigational therapy. Ann Surg Oncol. 2012 Jan; 19(1):199-206. PMID: 21769471; DOI: 10.1245/s10434-011-1871-4;

Zhang XX, McIntosh TJ, Grinstaff MW. Functional lipids and lipoplexes for improved gene delivery. Biochimie. 2012 Jan; 94(1):42-58. PMID: 21621581; PMCID: PMC3771368; DOI: 10.1016/j.biochi.2011.05.005;

Khoo X, Grinstaff MW. Novel Infection-Resistant Surface Coatings: A Bioengineering Approach (invited article). MRS Bulletin, Special Issue on Bateria Biofilms. 2011; 36:357-366. View Publication

Bansal PN, Stewart RC, Entezari V, Snyder BD, Grinstaff MW. Contrast agent electrostatic attraction rather than repulsion to glycosaminoglycans affords a greater contrast uptake ratio and improved quantitative CT imaging in cartilage. Osteoarthritis Cartilage. 2011 Aug; 19(8):970-6. PMID: 21549206; DOI: 10.1016/j.joca.2011.04.004;

Zhang XX, Prata CA, Berlin JA, McIntosh TJ, Barthelemy P, Grinstaff MW. Synthesis, characterization, and in vitro transfection activity of charge-reversal amphiphiles for DNA delivery. Bioconjug Chem. 2011 Apr 20; 22(4):690-9. PMID: 21456532; PMCID: PMC3878859; DOI: 10.1021/bc1004526;

Liu R, Khullar OV, Griset AP, Wade JE, Zubris KA, Grinstaff MW, Colson YL. Paclitaxel-loaded expansile nanoparticles delay local recurrence in a heterotopic murine non-small cell lung cancer model. Ann Thorac Surg. 2011 Apr; 91(4):1077-83; discussion 1083-4. PMID: 21440127; DOI: 10.1016/j.athoracsur.2010.12.040;

Zhang XX, Allen PG, Grinstaff M. Macropinocytosis is the major pathway responsible for DNA transfection in CHO cells by a charge-reversal amphiphile. Mol Pharm. 2011 Jun 6; 8(3):758-66. PMID: 21449536; PMCID: PMC3878857; DOI: 10.1021/mp100366h;

Oelker AM, Berlin JA, Wathier M, Grinstaff MW. Synthesis and characterization of dendron cross-linked PEG hydrogels as corneal adhesives. Biomacromolecules. 2011 May 9; 12(5):1658-65. PMID: 21417379; PMCID: PMC3878822; DOI: 10.1021/bm200039s;

Oumzil K, Khiati S, Grinstaff MW, Barthélémy P. Reduction-triggered delivery using nucleoside-lipid based carriers possessing a cleavable PEG coating. J Control Release. 2011 Apr 30; 151(2):123-30. PMID: 21354443; DOI: 10.1016/j.jconrel.2011.02.008;

Meyers SR, Kenan DJ, Khoo X, Grinstaff MW. Bioactive stent surface coating that promotes endothelialization while preventing platelet adhesion. Biomacromolecules. 2011 Mar 14; 12(3):533-9. PMID: 21218765; PMCID: PMC3064855; DOI: 10.1021/bm101212k;

Camplo M, Wathier M, Chow J, Grinstaff MW. A versatile reagent to synthesize diverse ionic liquids ranging from small molecules and dendrimers to functionalized proteins. Chem Commun (Camb). 2011 Feb 21; 47(7):2128-30. PMID: 21180737; DOI: 10.1039/c0cc04459h;

Bansal PN, Joshi NS, Entezari V, Malone BC, Stewart RC, Snyder BD, Grinstaff MW. Cationic contrast agents improve quantification of glycosaminoglycan (GAG) content by contrast enhanced CT imaging of cartilage. J Orthop Res. 2011 May; 29(5):704-9. PMID: 21437949; DOI: 10.1002/jor.21312;

Colson YL, Liu R, Southard EB, Schulz MD, Wade JE, Griset AP, Zubris KA, Padera RF, Grinstaff MW. The performance of expansile nanoparticles in a murine model of peritoneal carcinomatosis. Biomaterials. 2011 Jan; 32(3):832-40. PMID: 21044799; DOI: 10.1016/j.biomaterials.2010.09.059;

Wathier M, Grinstaff MW. Synthesis and Creep-Recovery Behavior of a Neat Viscoelastic Polymeric Network Formed Through Electrostatic Interactions. Macromolecules. 2010; 43:9529-9533. View Publication

Wathier M, Stoddart SS, Sheehy MJ, Grinstaff MW. Acidic polysaccharide mimics via ring-opening metathesis polymerization. J Am Chem Soc. 2010 Nov 17; 132(45):15887-9. PMID: 20964329; DOI: 10.1021/ja106488h;

Mintzer MA, Grinstaff MW. Biomedical applications of dendrimers: a tutorial. Chem Soc Rev. 2011 Jan; 40(1):173-90. PMID: 20877875; DOI: 10.1039/b901839p;

Khoo X, O'Toole GA, Nair SA, Snyder BD, Kenan DJ, Grinstaff MW. Staphylococcus aureus resistance on titanium coated with multivalent PEGylated-peptides. Biomaterials. 2010 Dec; 31(35):9285-92. PMID: 20863561; PMCID: PMC3777270; DOI: 10.1016/j.biomaterials.2010.08.031;

Zubris KA, Khullar OV, Griset AP, Gibbs-Strauss S, Frangioni JV, Colson YL, Grinstaff MW. Ease of synthesis, controllable sizes, and in vivo large-animal-lymph migration of polymeric nanoparticles. ChemMedChem. 2010 Sep 3; 5(9):1435-8. PMID: 20593440; PMCID: PMC3103777; DOI: 10.1002/cmdc.201000250;

Ceballos C, Khiati S, Prata CA, Zhang XX, Giorgio S, Marsal P, Grinstaff MW, Barthélémy P, Camplo M. Cationic nucleoside lipids derived from universal bases: A rational approach for siRNA transfection. Bioconjug Chem. 2010 Jun 16; 21(6):1062-9. PMID: 20481514; DOI: 10.1021/bc100005k;

Cong H, Becker CF, Elliott SJ, Grinstaff MW, Porco JA. Silver nanoparticle-catalyzed Diels-Alder cycloadditions of 2'-hydroxychalcones. J Am Chem Soc. 2010 Jun 2; 132(21):7514-8.View Related Profiles.

Porco, John
Grinstaff, Mark
Elliott, Sean

PMID: 20443601; PMCID: PMC2882859; DOI: 10.1021/ja102482b;

Schulz MD, Khullar O, Frangioni JV, Grinstaff MW, Colson YL. Nanotechnology in thoracic surgery. Ann Thorac Surg. 2010 Jun; 89(6):S2188-90. PMID: 20494008; PMCID: PMC3098441; DOI: 10.1016/j.athoracsur.2010.02.111;

Zhang XX, Prata CA, McIntosh TJ, Barthélémy P, Grinstaff MW. The effect of charge-reversal amphiphile spacer composition on DNA and siRNA delivery. Bioconjug Chem. 2010 May 19; 21(5):988-93. PMID: 20433165; PMCID: PMC3052776; DOI: 10.1021/bc9005464;

Huang X, Zauscher S, Klitzman B, Truskey GA, Reichert WM, Kenan DJ, Grinstaff MW. Peptide interfacial biomaterials improve endothelial cell adhesion and spreading on synthetic polyglycolic acid materials. Ann Biomed Eng. 2010 Jun; 38(6):1965-76. PMID: 20300848; DOI: 10.1007/s10439-010-9986-5;

Wolinsky JB, Liu R, Walpole J, Chirieac LR, Colson YL, Grinstaff MW. Prevention of in vivo lung tumor growth by prolonged local delivery of hydroxycamptothecin using poly(ester-carbonate)-collagen composites. J Control Release. 2010 Jun 15; 144(3):280-7. PMID: 20184934; DOI: 10.1016/j.jconrel.2010.02.022;

Liu R, Wolinsky JB, Walpole J, Southard E, Chirieac LR, Grinstaff MW, Colson YL. Prevention of local tumor recurrence following surgery using low-dose chemotherapeutic polymer films. Ann Surg Oncol. 2010 Apr; 17(4):1203-13. PMID: 19957041; DOI: 10.1245/s10434-009-0856-z;

Bansal PN, Joshi NS, Entezari V, Grinstaff MW, Snyder BD. Contrast enhanced computed tomography can predict the glycosaminoglycan content and biomechanical properties of articular cartilage. Osteoarthritis Cartilage. 2010 Feb; 18(2):184-91. PMID: 19815108; DOI: 10.1016/j.joca.2009.09.003;

Joshi NS, Bansal PN, Stewart RC, Snyder BD, Grinstaff MW. Effect of contrast agent charge on visualization of articular cartilage using computed tomography: exploiting electrostatic interactions for improved sensitivity. J Am Chem Soc. 2009 Sep 23; 131(37):13234-5. PMID: 19754183; DOI: 10.1021/ja9053306;

Khiati S, Pierre N, Andriamanarivo S, Grinstaff MW, Arazam N, Nallet F, Navailles L, Barthélémy P. Anionic nucleotide--lipids for in vitro DNA transfection. Bioconjug Chem. 2009 Sep; 20(9):1765-72. PMID: 19711898; DOI: 10.1021/bc900163s;

Khoo X, Hamilton P, O'Toole GA, Snyder BD, Kenan DJ, Grinstaff MW. Directed assembly of PEGylated-peptide coatings for infection-resistant titanium metal. J Am Chem Soc. 2009 Aug 12; 131(31):10992-7. PMID: 19621876; DOI: 10.1021/ja9020827;

Johnson CS, Wathier M, Grinstaff M, Kim T. In vitro sealing of clear corneal cataract incisions with a novel biodendrimer adhesive. Arch Ophthalmol. 2009 Apr; 127(4):430-4. PMID: 19365019; DOI: 10.1001/archophthalmol.2009.46;

Berdahl JP, Johnson CS, Proia AD, Grinstaff MW, Kim T. Comparison of sutures and dendritic polymer adhesives for corneal laceration repair in an in vivo chicken model. Arch Ophthalmol. 2009 Apr; 127(4):442-7. PMID: 19365021; DOI: 10.1001/archophthalmol.2008.582;

Griset AP, Walpole J, Liu R, Gaffey A, Colson YL, Grinstaff MW. Expansile nanoparticles: synthesis, characterization, and in vivo efficacy of an acid-responsive polymeric drug delivery system. J Am Chem Soc. 2009 Feb 25; 131(7):2469-71. PMID: 19182897; DOI: 10.1021/ja807416t;

Ceballos C, Prata CA, Giorgio S, Garzino F, Payet D, Barthélémy P, Grinstaff MW, Camplo M. Cationic nucleoside lipids based on a 3-nitropyrrole universal base for siRNA delivery. Bioconjug Chem. 2009 Feb; 20(2):193-6. PMID: 19159294; PMCID: PMC2819530; DOI: 10.1021/bc800432n;

Khullar O, Frangioni JV, Grinstaff M, Colson YL. Image-guided sentinel lymph node mapping and nanotechnology-based nodal treatment in lung cancer using invisible near-infrared fluorescent light. Semin Thorac Cardiovasc Surg. 2009; 21(4):309-15. PMID: 20226343; PMCID: PMC3109504; DOI: 10.1053/j.semtcvs.2009.11.009;

Meyers SR, Kenan DJ, Grinstaff MW. Enzymatic release of a surface-adsorbed RGD therapeutic from a cleavable peptide anchor. ChemMedChem. 2008 Nov; 3(11):1645-8. PMID: 18792896; DOI: 10.1002/cmdc.200800205;

Meyers SR, Khoo X, Huang X, Walsh EB, Grinstaff MW, Kenan DJ. The development of peptide-based interfacial biomaterials for generating biological functionality on the surface of bioinert materials. Biomaterials. 2009 Jan; 30(3):277-86. PMID: 18929406; PMCID: PMC3878816; DOI: 10.1016/j.biomaterials.2008.08.042;

Moreau L, Camplo M, Wathier M, Taib N, Laguerre M, Bestel I, Grinstaff MW, Barthélémy P. Real time imaging of supramolecular assembly formation via programmed nucleolipid recognition. J Am Chem Soc. 2008 Nov 5; 130(44):14454-5. PMID: 18850703; DOI: 10.1021/ja805974g;

Meyers SR, Juhn FS, Griset AP, Luman NR, Grinstaff MW. Anionic amphiphilic dendrimers as antibacterial agents. J Am Chem Soc. 2008 Nov 5; 130(44):14444-5. PMID: 18842041; PMCID: PMC2673084; DOI: 10.1021/ja806912a;

Degoricija L, Bansal PN, Söntjens SH, Joshi NS, Takahashi M, Snyder B, Grinstaff MW. Hydrogels for osteochondral repair based on photocrosslinkable carbamate dendrimers. Biomacromolecules. 2008 Oct; 9(10):2863-72. PMID: 18800810; PMCID: PMC2819483; DOI: 10.1021/bm800658x;

Wathier M, Grinstaff MW. Synthesis and properties of supramolecular ionic networks. J Am Chem Soc. 2008 Jul 30; 130(30):9648-9. PMID: 18593156; DOI: 10.1021/ja803248q;

Walpole J, Griset A, Gaffey A, Grinstaff MW, Colson Y. Effect of expansile paclitaxel-loaded nanoparticles on growth of lung cancer in vivo. J Clin Oncol. 2008 May 20; 26(15_suppl):7593. PMID: 27947401

Azouz SM, Walpole J, Amirifeli S, Taylor KN, Grinstaff MW, Colson YL. Prevention of local tumor growth with paclitaxel-loaded microspheres. J Thorac Cardiovasc Surg. 2008 May; 135(5):1014-21. PMID: 18455578; DOI: 10.1016/j.jtcvs.2007.12.011;

Bestel I, Campins N, Marchenko A, Fichou D, Grinstaff MW, Barthélémy P. Two-dimensional self-assembly and complementary base-pairing between amphiphile nucleotides on graphite. J Colloid Interface Sci. 2008 Jul 15; 323(2):435-40. PMID: 18468614; DOI: 10.1016/j.jcis.2008.04.042;

Oelker AM, Grinstaff MW. Ophthalmic Adhesives: A Materials Chemistry Perspective (invited application article). Journal of Materials Chemistry. 2008; 18:2521-2536. View Publication

De Jong L, Moreau X, Thiéry A, Godeau G, Grinstaff MW, Barthélémy P. Amphiphilic copolymer for delivery of xenobiotics: in vivo studies in a freshwater invertebrate, a Mesostominae flatworm. Bioconjug Chem. 2008 Apr; 19(4):891-8. PMID: 18341271; DOI: 10.1021/bc700425x;

Gissot A, Camplo M, Grinstaff MW, Barthélémy P. Nucleoside, nucleotide and oligonucleotide based amphiphiles: a successful marriage of nucleic acids with lipids. Org Biomol Chem. 2008 Apr 21; 6(8):1324-33. PMID: 18385837; PMCID: PMC2817972; DOI: 10.1039/b719280k;

Wolinsky JB, Grinstaff MW. Therapeutic and diagnostic applications of dendrimers for cancer treatment. Adv Drug Deliv Rev. 2008 Jun 10; 60(9):1037-55. PMID: 18448187; DOI: 10.1016/j.addr.2008.02.012;

Prata CA, Li Y, Luo D, McIntosh TJ, Barthelemy P, Grinstaff MW. A new helper phospholipid for gene delivery. Chem Commun (Camb). 2008 Apr 7; (13):1566-8. PMID: 18354801; PMCID: PMC2817970; DOI: 10.1039/b716247b;

Prata CA, Zhang XX, Luo D, McIntosh TJ, Barthelemy P, Grinstaff MW. Lipophilic peptides for gene delivery. Bioconjug Chem. 2008 Feb; 19(2):418-20. PMID: 18186598; PMCID: PMC2817964; DOI: 10.1021/bc700451b;

Grinstaff MW. Dendritic Macromers for Hydrogel Formation: Tailored Materials for Ophthalmic, Orthopedic, and Biotech Applications (invited highlight article). Journal of Polymer Science Part A: Polymer Chemistry. 2008; 46:383-400. View Publication

Joshi N, Grinstaff M. Applications of dendrimers in tissue engineering. Curr Top Med Chem. 2008; 8(14):1225-36. PMID: 18855707

Campins N, Dieudonné P, Grinstaff MW, Barthélémy P. Nanostructured Assemblies from Nucleotide Based Amphiphiles. New Journal of Chemistry. 2007; 31:1928-1934. View Publication

Grinstaff MW. Designing hydrogel adhesives for corneal wound repair. Biomaterials. 2007 Dec; 28(35):5205-14. PMID: 17889330; PMCID: PMC3878817; DOI: 10.1016/j.biomaterials.2007.08.041;

Wolinsky JB, Ray III WC, Colson YL, Grinstaff MW. Poly(carbonate-ester)s Based on Units of 6-Hydroxyhexanoic Acid and Glycerol. Macromolecules. 2007; 40:7065-7068. View Publication
Meyers SR, Hamilton PT, Walsh EB, Kenan DJ, Grinstaff MW. Endothelialization of Titanium Surfaces. Advanced Materials. 2007; 19:2492-2498. View Publication

Degoricija L, Johnson CS, Wathier M, Kim T, Grinstaff MW. Photo cross-linkable Biodendrimers as ophthalmic adhesives for central lacerations and penetrating keratoplasties. Invest Ophthalmol Vis Sci. 2007 May; 48(5):2037-42. PMID: 17460258

Dominguez MM, Wathier M, Grinstaff MW, Schaus SE. Immobilized hydrogels for screening of molecular interactions. Anal Chem. 2007 Feb 1; 79(3):1064-6.View Related Profiles.

Grinstaff, Mark
Schaus, Scott

PMID: 17263336

Degoricija L, Carnahan MA, Johnson CS, Kim T, Grinstaff MW. Synthesis and Characterization of Bola-type Amphiphilic Dendritic Macromolecules. Macromolecules. 2006; 39:8952-8958. View Publication

Morgan MT, Nakanishi Y, Kroll DJ, Griset AP, Carnahan MA, Wathier M, Oberlies NH, Manikumar G, Wani MC, Grinstaff MW. Dendrimer-encapsulated camptothecins: increased solubility, cellular uptake, and cellular retention affords enhanced anticancer activity in vitro. Cancer Res. 2006 Dec 15; 66(24):11913-21. PMID: 17178889

Moreau L, Campins N, Grinstaff MW, Barthélémy P. A Fluorocarbon Nucleoamphiphile for the Construction of Actinide Loaded Microspheres. Tetrahedron Letters. 2006; 47:7117-7120. View Publication

Wathier M, Johnson MS, Carnahan MA, Baer C, McCuen BW, Kim T, Grinstaff MW. In situ polymerized hydrogels for repairing scleral incisions used in pars plana vitrectomy procedures. ChemMedChem. 2006 Aug; 1(8):821-5. PMID: 16902936

Kenan DJ, Walsh EB, Meyers SR, O'Toole GA, Carruthers EG, Lee WK, Zauscher S, Prata CA, Grinstaff MW. Peptide-PEG amphiphiles as cytophobic coatings for mammalian and bacterial cells. Chem Biol. 2006 Jul; 13(7):695-700. PMID: 16873017

Wathier M, Johnson CS, Kim T, Grinstaff MW. Hydrogels formed by multiple peptide ligation reactions to fasten corneal transplants. Bioconjug Chem. 2006 Jul-Aug; 17(4):873-6. PMID: 16848392

Weinstein JA, Tierney MT, Davies ES, Base K, Robeiro AA, Grinstaff MW. Probing the electronic structure of platinum(II) chromophores: crystal structures, NMR structures, and photophysical properties of six new bis- and di- phenolate/thiolate Pt(II)diimine chromophores. Inorg Chem. 2006 May 29; 45(11):4544-55. PMID: 16711705

Moreau L, Ziarelli F, Grinstaff MW, Barthélémy P. Self-assembled microspheres from f-block elements and nucleoamphiphiles. Chem Commun (Camb). 2006 Apr 21; (15):1661-3. PMID: 16583012

Chabaud P, Camplo M, Payet D, Serin G, Moreau L, Barthélémy P, Grinstaff MW. Cationic nucleoside lipids for gene delivery. Bioconjug Chem. 2006 Mar-Apr; 17(2):466-72. PMID: 16536479

Carnahan MA, Grinstaff MW. Synthesis of Generational Polyester Dendrimers Derived from Glycerol and Succinic or Adipic Acid. Macromolecules. 2006; 39:609-616. View Publication

Söntjens SH, Nettles DL, Carnahan MA, Setton LA, Grinstaff MW. Biodendrimer-based hydrogel scaffolds for cartilage tissue repair. Biomacromolecules. 2006 Jan; 7(1):310-6. PMID: 16398530

Prata CA, Li Y, Luo D, McIntosh TJ, Grinstaff MW. Non-viral charge reversal vectors for pDNA delivery. Conf Proc IEEE Eng Med Biol Soc. 2006; 1:4347-9. PMID: 17946624

Barthélémy P, Lee SJ, Grinstaff MW. Supramolecular Assemblies with DNA (Invited Special Topic Article). Pure and Applied Chemistry. 2005; 77:2133-2148. View Publication

Luman NR, Grinstaff MW. Synthesis and aqueous aggregation properties of amphiphilic surface-block dendrimers. Org Lett. 2005 Oct 27; 7(22):4863-6. PMID: 16235908

Reineke TM, Grinstaff MW. Designer Materials for Nucleic Acid Delivery (Invited Editorial Article/Special Issue on Gene Delivery). Material Research Society Bulletin. 2005; 30:635-639. View Publication

Moreau L, Barthélémy P, Li Y, Luo D, Prata CA, Grinstaff MW. Nucleoside phosphocholine amphiphile for in vitro DNA transfection. Mol Biosyst. 2005 Sep; 1(3):260-4. PMID: 16880990

Morgan MT, Carnahan MA, Finkelstein S, Prata CA, Degoricija L, Lee SJ, Grinstaff MW. Dendritic supramolecular assemblies for drug delivery. Chem Commun (Camb). 2005 Sep 14; (34):4309-11. PMID: 16113731

Arigon J, Prata CA, Grinstaff MW, Barthélémy P. Nucleic acid complexing glycosyl nucleoside-based amphiphile. Bioconjug Chem. 2005 Jul-Aug; 16(4):864-72. PMID: 16029028

Kang PC, Carnahan MA, Wathier M, Grinstaff MW, Kim T. Novel tissue adhesives to secure laser in situ keratomileusis flaps. J Cataract Refract Surg. 2005 Jun; 31(6):1208-12. PMID: 16039499

Moreau L, Grinstaff MW, Barthélémy P. Vesicle Formation from a Synthetic Adenosine Based Lipid. Tetrahedron Letters. 2005; 46:1593-1596. View Publication

Barthelemy P, Prata CA, Filocamo SF, Immoos CE, Maynor BW, Hashmi SA, Lee SJ, Grinstaff MW. Supramolecular assemblies of DNA with neutral nucleoside amphiphiles. Chem Commun (Camb). 2005 Mar 14; (10):1261-3. PMID: 15742045

Wathier M, Jung PJ, Carnahan MA, Kim T, Grinstaff MW. Dendritic macromers as in situ polymerizing biomaterials for securing cataract incisions. J Am Chem Soc. 2004 Oct 13; 126(40):12744-5. PMID: 15469247

Prata CA, Zhao Y, Barthelemy P, Li Y, Luo D, McIntosh TJ, Lee SJ, Grinstaff MW. Charge-reversal amphiphiles for gene delivery. J Am Chem Soc. 2004 Oct 6; 126(39):12196-7. PMID: 15453715

Immoos CE, Lee SJ, Grinstaff MW. DNA-PEG-DNA triblock macromolecules for reagentless DNA detection. J Am Chem Soc. 2004 Sep 8; 126(35):10814-5. PMID: 15339145

Immoos CE, Lee SJ, Grinstaff MW. Conformationally gated electrochemical gene detection. Chembiochem. 2004 Aug 6; 5(8):1100-3. PMID: 15300834

Moreau L, Barthélémy P, El Maataoui M, Grinstaff MW. Supramolecular assemblies of nucleoside phosphocholine amphiphiles. J Am Chem Soc. 2004 Jun 23; 126(24):7533-9. PMID: 15198600

Velazquez AJ, Carnahan MA, Kristinsson J, Stinnett S, Grinstaff MW, Kim T. New dendritic adhesives for sutureless ophthalmic surgical procedures: in vitro studies of corneal laceration repair. Arch Ophthalmol. 2004 Jun; 122(6):867-70. PMID: 15197062

Nettles DL, Vail TP, Morgan MT, Grinstaff MW, Setton LA. Photocrosslinkable hyaluronan as a scaffold for articular cartilage repair. Ann Biomed Eng. 2004 Mar; 32(3):391-7. PMID: 15095813

Morgan MT, Carnahan MA, Immoos CE, Ribeiro AA, Finkelstein S, Lee SJ, Grinstaff MW. Dendritic molecular capsules for hydrophobic compounds. J Am Chem Soc. 2003 Dec 17; 125(50):15485-9. PMID: 14664594

Luman NR, Smeds KA, Grinstaff MW. The convergent synthesis of poly(glycerol-succinic acid) dendritic macromolecules. Chemistry. 2003 Nov 21; 9(22):5618-26. PMID: 14639645

Holmberg RC, Tierney MT, Ropp PA, Berg EE, Grinstaff MW, Thorp HH. Intramolecular electrocatalysis of 8-oxo-guanine oxidation: secondary structure control of electron transfer in osmium-labeled oligonucleotides. Inorg Chem. 2003 Oct 6; 42(20):6379-87. PMID: 14514313

Prabhakar V, Grinstaff MW, Alarcon J, Knors C, Solan AK, Niklason LE. Engineering porcine arteries: effects of scaffold modification. J Biomed Mater Res A. 2003 Oct 1; 67(1):303-11. PMID: 14517890

Ray III WC, Grinstaff MW. Polycarbonate and Polycarbonate-esters Synthesized from Biocompatible Building Blocks of Glycerol and Lactic Acid. Macromolecules. 2003; 36:3557-3562. View Publication

Hashmi SA, Hu X, Immoos CE, Lee SJ, Grinstaff MW. Synthesis and characterization of pi-stacked phenothiazine-labeled oligodeoxynucleotides. Org Lett. 2002 Dec 26; 4(26):4571-4. PMID: 12489932

Hird GS, Grinstaff MW. Synthesis and characterization of a dianionic carbohydrate-based phospholipid. Chem Phys Lipids. 2002 Dec; 120(1-2):1-7. PMID: 12426071

Grinstaff MW. Biodendrimers: new polymeric biomaterials for tissue engineering. Chemistry. 2002 Jul 2; 8(13):2839-46. PMID: 12489212

Hird GS, McIntosh TJ, Ribeiro AA, Grinstaff MW. Synthesis and characterization of carbohydrate-based phospholipids. J Am Chem Soc. 2002 May 29; 124(21):5983-92. PMID: 12022831

Carnahan MA, Middleton C, Kim J, Kim T, Grinstaff MW. Hybrid dendritic-linear polyester-ethers for in situ photopolymerization. J Am Chem Soc. 2002 May 15; 124(19):5291-3. PMID: 11996569

Miki D, Dastgheib K, Kim T, Pfister-Serres A, Smeds KA, Inoue M, Hatchell DL, Grinstaff MW. A photopolymerized sealant for corneal lacerations. Cornea. 2002 May; 21(4):393-9. PMID: 11973389

Maynor BW, Filocamo SF, Grinstaff MW, Liu J. Direct-writing of polymer nanostructures: poly(thiophene) nanowires on semiconducting and insulating surfaces. J Am Chem Soc. 2002 Jan 30; 124(4):522-3. PMID: 11804474

Hu X, Tierney MT, Grinstaff MW. Synthesis and characterization of phenothiazine labeled oligodeoxynucleotides: novel 2'-deoxyadenosine and thymidine probes for labeling DNA. Bioconjug Chem. 2002 Jan-Feb; 13(1):83-9. PMID: 11792181

Hu X, Lee SJ, Grinstaff MW. Nucleobase and 5'-terminal probes for DNA redox chemistry. Methods Enzymol. 2002; 353:548-66. PMID: 12078527

Beilstein AE, Grinstaff MW. Synthesis and Characterization of Fc Labeled Oligodeoxynucleotides (invited article; special issue marking the 50th anniversary of ferrocene). Journal of Organometallic Chemistry. 2001; 637-639, 398-406. View Publication
Carnahan MA, Grinstaff MW. Synthesis and Characterization of Poly(glycerol-succinic acid) Dendrimers. Macromolecules. 2001; 34:7648-7655. View Publication
Smith GD, Hutson MS, Lu Y, Tierney MT, Grinstaff MW, Palmer R. Step-Scan FTIR Time-Resolved Spectroscopy in the Solid-State. Applied Spectroscopy. 2001; 55:637-642. View Publication

Carnahan MA, Grinstaff MW. Synthesis and characterization of polyether-ester dendrimers from glycerol and lactic acid. J Am Chem Soc. 2001 Mar 28; 123(12):2905-6. PMID: 11456987

Carnahan MA, Grinstaff MW. Synthesis and Characterization of Polyether-ester Dendrimers Composed of Glycerol and Lactic Acid. Journal of the American Chemical Society. 2001; 123:2905-2906. View Publication

Smeds KA, Pfister-Serres A, Miki D, Dastgheib K, Inoue M, Hatchell DL, Grinstaff MW. Photocrosslinkable polysaccharides for in situ hydrogel formation. J Biomed Mater Res. 2001 Jan; 54(1):115-21. PMID: 11077410

Tierney MT, Grinstaff MW. Synthesis and stability of oligodeoxynucleotides containing C8-labeled 2'-deoxyadenosine: novel redox nucleobase probes for DNA-mediated charge-transfer studies. Org Lett. 2000 Nov 2; 2(22):3413-6. PMID: 11081996

Tierney MT, Grinstaff MW. Synthesis and characterization of fluorenone-, anthraquinone-, and phenothiazine-labeled oligodeoxynucleotides: 5'-probes for DNA redox chemistry. J Org Chem. 2000 Aug 25; 65(17):5355-9. PMID: 10993366

Tierney MT, Sykora M, Khan SI, Grinstaff MW. Photoinduced Electron Transfer in an Oligonucleotide Duplex: Observation of the Electron-Transfer Intermediate. Journal of Physical Chemistry B. 2000; 104:7574-7576. View Publication
Hird GS, McIntosh TJ, Grinstaff MW. Supramolecular Structures of Novel Carbohydrate Based Phospholipids. Journal of the American Chemical Society. 2000; 122:8097-8098. View Publication

Hu X, Smith GD, Sykora M, Lee SJ, Grinstaff MW. Automated solid-phase synthesis and photophysical properties of oligodeoxynucleotides labeled at 5'-aminothymidine with Ru(bpy)2(4-m-4'-cam-bpy)2+. Inorg Chem. 2000 Jun 12; 39(12):2500-4. PMID: 11197001

Beilstein AE, Grinstaff MW. On-Column Derivatization of Oligodeoxynucleotides with Ferrocene. Chemical Communications. 2000; 509-510. View Publication

Khan SI, Beilstein AE, Tierney MT, Sykora M, Grinstaff MW. Solid-Phase Synthesis and Photophysical Properties of DNA Labeled at the Nucleobase with Ru(bpy)(2)(4-m-4'-pa-bpy)(2+). Inorg Chem. 1999 Dec 27; 38(26):5999-6002. PMID: 11671306

Grinstaff MW. How Do Charges Travel through DNA?-An Update on a Current Debate. Angew Chem Int Ed Engl. 1999 Dec 16; 38(24):3629-3635. PMID: 10649307

Khan SI, Beilstein AE, Smith GD, Sykora M, Grinstaff MW. Synthesis and Excited-State Properties of a Novel Ruthenium Nucleoside: 8 Ru(bpy)2(5-bpy-2'-deoxyuridine)2+. Inorganic Chemistry. 1999; 38:2411-2415. View Publication
Khan SI, Grinstaff MW. Palladium(0) Catalyzed Modification of Oligonucleotides during Automated SolidPhase Synthesis. Journal of the American Chemical Society. 1999; 121:4704-4705. View Publication

Khan SI, Beilstein AE, Grinstaff MW. Automated Solid-Phase Synthesis of Site-Specifically Labeled Ruthenium-Oligonucleotides. Inorg Chem. 1999 Feb 08; 38(3):418-419. PMID: 11673940

Khan SI, Grinstaff MW. The Alkylation of Iodouridine by a Heterogeneous Palladium Catalyst. J Org Chem. 1999 Feb 05; 64(3):1077-1078. PMID: 11674196

Base K, Tierney MA, Fort A, Muller J, Grinstaff MW. On the Second-Order Nonlinear Optical Structure-Property Relationships of Metal Chromophores. Inorganic Chemistry. 1999; 38:287-289. View Publication
Smeds KA, Pfister-Serres A, Hatchell DL, Saloupis P, Grinstaff MW. Synthesis of a Novel Polysaccharide Hydrogel. Journal of Macromolecular Sciences. 1999; A36:981-989. View Publication
Khan SI, Grinstaff MW. A Facile and Convenient Solid-Phase Procedure for Synthesizing Nucleoside Hydroxamic Acids. Tetrahedron Letters. 1998; 39:8031-8034. View Publication
Base K, Grinstaff MW. Generation of an Unprecedented Excited State Oxidant in a Coordinately Unsaturated Platinum Complex. Inorganic Chemistry. 1998; 37:1432-1433. View Publication

DeHaan FP, Djaputra M, Grinstaff MW, Kaufman CR, Keithly JC, Kumar A, Kuwayama MK, Macknet KD, Na J, Patel BR, Pinkerton MJ, Tidwell JH, Villahermosa RM. Electrophilic Aromatic Substitution. 13.(1) Kinetics and Spectroscopy of the Chloromethylation of Benzene and Toluene with Methoxyacetyl Chloride or Chloromethyl Methyl Ether and Aluminum Chloride in Nitromethane or Tin Tetrachloride in Dichloromethane. The Methoxymethyl Cation as a Remarkably Selective Common Electrophile. J Org Chem. 1997 May 02; 62(9):2694-2703. PMID: 11671627

Bottcher A, Birnbaum ER, Labinger JA, Grinstaff MW, Gray HB. How Do Electronegative Substitutents Make Metal Complexes Better Catalysts for the Oxidation of Hydrocarbons by Dioxygen?. Journal of Molecular Catalysis. 1997; 117:229-242. View Publication
Bottcher A, Grinstaff MW, Labinger JA, Gray HB. Aerobic Oxidation of Hydrocarbons Catalyzed by Electronegative Iron Salen Complexes. Journal of Molecular Catalysis. 1996; 113:191-200. View Publication

Eckburg JJ, Chato JC, Liu KJ, Grinstaff MW, Swartz HM, Suslick KS, Auteri FP. The measurement of temperature with electron paramagnetic resonance spectroscopy. J Biomech Eng. 1996 May; 118(2):193-200. PMID: 8738784

Birnbaum ER, Grinstaff MW, Labinger JA, Bercaw JE, Gray HB. On the Mechanism of Catalytic Alkene Oxidation by Molecular Oxygen and Halogenated Iron Porphyrins. Journal of Molecular Catalysis. 1995; 104:L119-L122. View Publication
Grinstaff MW, Hill MG, Birnbaum ER, Schaefer WP, Labinger JA, Gray HB. Structure, Electronic Properties, and Oxidation-Reduction Reactivity of Halogenated Iron Porphyrins. Inorganic Chemistry. 1995; 34:4896-4902. View Publication
Birnbaum ER, Hodge JA, Grinstaff MW, Schaefer WP, Henling L, Labinger JA, Bercaw JE, Gray HB. 19F-NMR Spectra and Structures of Halogenated Porphyrins. Inorganic Chemistry. 1995; 34:3625-3632. View Publication

Liu KJ, Grinstaff MW, Jiang J, Suslick KS, Swartz HM, Wang W. In vivo measurement of oxygen concentration using sonochemically synthesized microspheres. Biophys J. 1994 Aug; 67(2):896-901. PMID: 7948703; PMCID: PMC1225433

Grinstaff MW, Hill MG, Labinger JA, Gray HB. Mechanism of catalytic oxygenation of alkanes by halogenated iron porphyrins. Science. 1994 May 27; 264(5163):1311-3. PMID: 8191283

Karpishin TB, Grinstaff MW, Komar-Panicucci S, McLendon G, Gray HB. Electron transfer in cytochrome c depends upon the structure of the intervening medium. Structure. 1994 May 15; 2(5):415-22. PMID: 8081757

Suslick KS, Grinstaff MW, Kolbeck KJ, Wong M. Characterization of Sonochemically Prepared Proteinaceous Microspheres. Ultrasonics Sonochemistry. 1994; 1:S65-S68. View Publication

Bellissent R, Galli G, Grinstaff MW, Migliardo P, Suslick KS. Neutron diffraction on amorphous iron powder. Phys Rev B Condens Matter. 1993 Dec 01; 48(21):15797-15800. PMID: 10008134

Grinstaff MW, Salamon MB, Suslick KS. Magnetic properties of amorphous iron. Phys Rev B Condens Matter. 1993 Jul 01; 48(1):269-273. PMID: 10006773

Suslick KS, Flint EB, Grinstaff MW, Kemper KA. Sonoluminescence from Metal Carbonyls. Journal of Physical Chemistry. 1993; 97:3098-3099. View Publication
Grinstaff MW, Suslick KS. Proteinaceous Microspheres. Macromolecular Assemblies; Stroeve P and Balazs A.C, eds.; ACS Symposium Series; Washington, D.C. 1992; 218-226. View Publication
Grinstaff MW, Cichowlas AA, Choe SB, Suslick KS. Effect of Cavitation Conditions on Amorphous Metal Synthesis. Ultrasonics. 1992; 30:168-172. View Publication
Suslick KS, Choe SB, Cichowlas AA, Grinstaff MW. Sonochemical Synthesis of Amorphous Iron. Nature. 1991; 353:414-416. View Publication

Grinstaff MW, Suslick KS. Air-filled proteinaceous microbubbles: synthesis of an echo-contrast agent. Proc Natl Acad Sci U S A. 1991 Sep 1; 88(17):7708-10. PMID: 1652761; PMCID: PMC52371

Suslick KS, Grinstaff MW. Protein Microencapsulation of Nonaqueous Liquids. Journal of the American Chemical Society. 1990; 112:7807-7809. View Publication

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 409 publications over 35 distinct years, with a maximum of 26 publications in 2016 and 2019

Bar chart showing 409 publications over 35 distinct years, with a maximum of 26 publications in 2016 and 2019

Year	Publications
1990	1
1991	2
1992	2
1993	3
1994	4
1995	3
1996	2
1997	2
1998	2
1999	8
2000	6
2001	6
2002	9
2003	5
2004	7
2005	9
2006	12
2007	6
2008	17
2009	10
2010	14
2011	18
2012	19
2013	19
2014	12
2015	17
2016	26
2017	19
2018	24
2019	26
2020	21
2021	21
2022	24
2023	15
2024	18

Note: X.com has changed/limited the ability to embed tweets directly in external sites and we are investigating ways to restore that functionality in BU Profiles. In the meantime we are displaying a link to your x.com profile in the Websites section above.

Mark Grinstaff on Research

College of Engineering 2015 Charles Delisi Distinguished Lecture

Head & Neck Cancer Symposium: New Technologies and Patient Care Delivery Panel

Nanopore Nonafiber Mesh Biosensor

Commercialization Apprenticeship Panel Series - Faculty Perspectives on Commercialization -September 18, 2014 @ Harvard Medical School

Pittcon 2014 - Cancer Nanotechnology Symposia: Presentation 3

Detecting and Treating Arthritis

Super-fast setting sticky polymers can suture tricky internal wounds

Chemistry World 8/28/2024

Modified Self-Amplifying RNA Provides Opportunities For New Vaccines And Treatments

Forbes 7/23/2024

Self-copying RNA vaccine wins first full approval: what’s next?

Nature 12/6/2023

BU Ignition Awards to Accelerate Products for Repairing Damaged Teeth, Fighting Cancer, Boosting Reading Skills, and More

The Brink 9/19/2023

Inventor Mark Grinstaff Named an AAAS Fellow

BU Today 2/14/2022

2021 AAAS Fellows

AAAS 1/24/2022

Simple process unlocks DNA’s potential to make biomaterials

Chemical & Engineering News 6/19/2020

Sustainable adhesives of the future won’t stick around

National Science Foundation 3/23/2020

Band-Aid Adhesive Replacement Won’t Ruin The Planet

Futurity 12/18/2019

Research Reveals a Natural Pregnancy Hormone Could Relax a Locked-up Joint

R&D Magazine 6/7/2019

Pregnancy Hormone Loosens ‘Frozen Shoulder’

Futurity 6/4/2019

Crossing the Scientific Aisle to Advance Tissue Engineering

BU Today 1/18/2019

Researchers develop self-lubricating condom to stem spread of STDs

Plastics Today 10/23/2018

A Self-Lubricating Condom is Almost Here. Will It Change Sex Forever?

Instinct 10/23/2018

This self-lubing condom lasts for 1,000 thrusts–and could change sex

Fast Company 10/22/2018

Boston University scientists develop new condom they hope will encourage broader use

The Boston Globe 10/19/2018

Scientists created a condom that self-lubricates during sex. You’re welcome

Digital Trends 10/18/2018

E-cigarettes Prevent Wound Healing

The Daily Mail 10/18/2018

E-cigarettes Slowed Wound Healing in Animal Study

HealthDay 10/18/2018

New Self-Lubricating Condom Would Revolutionize Safe Sex

BU Today 10/18/2018

New self-lubricating condoms could boost their use, prevent STDs

CNN 10/17/2018

Self-lubricating condom design may encourage safe sex

The Guardian 10/16/2018

2012 National Academy of Inventors Charter Fellow

2012 Kern Faculty Fellow

2011 Stevenson Biomaterials Lecturer, Syracuse Biomaterials Institute, Syracuse University

2010 Boston University Innovator of the Year

2010 Elected to AIMBE (College of Fellows of the American Institute for Medical & Biomedical Engineering)

2010 Professeur Invité and Certificat sur Honneur, Université de Bordeaux (Bordeaux II)

2009 COE Distinguished Faculty Fellow (5-year Endowed Fellowship)

2008 Edward M. Kennedy Award for Health Care Innovation

2007 Professeurr Invité and Certificat sur Honneur, Université de la Maditerranée (Aix-Marseille II)

2006 Elected Fellow of the American Academy of Nanomedicine

2001 3M Non-Tenured Faculty Award

2001 Johnson and Johnson Focused Giving Grant Recipient

2000 Camille Dreyfus Teacher-Scholar

2000 Alfred P. Sloan Research Fellowship

1999 Pew Scholar in the Biomedical Sciences

1999 NSF Career Award

1998 Whitaker Foundation Grant Recipient

1994 ACS Nobel Laureate Signature Award

1993 NIH Postdoctoral Fellowship

1991 T.S. Piper Award for Outstanding Inorganic Research

1990 The ACS Fellowship of the Colloid & Surface Division (Sponsored by Procter & Gamble)

1989 University of Illinois Chemistry Department Fellowship

In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Biomaterials
Drug Delivery
Macromolecular Chemistry and Engineering
Nanodevices
Self-Assembly
Tissue Engineering

Contact for Mentoring:

590 Commonwealth Ave
Boston MA 02215
Google Map

617.358.3429

Download vCard

Grinstaff's Networks

Click the "See All" links for more information and interactive visualizations

Concepts

See all (844) concept(s)

Media Mentions

Co-Authors

See all (47) people

Similar People

See all (60) people