Keywords
Last Name

Michael J. O'Brien, MD

TitleProfessor
InstitutionBoston University School of Medicine
DepartmentPathology & Laboratory Medicine
DivisionAnatomic Pathology
Address670 Albany St Biosquare III
Boston MA 02118
Phone(617) 414-4988
ORCID ORCID Icon0000-0003-1124-3537
Other Positions
TitleChief
InstitutionBoston University School of Medicine
DepartmentPathology & Laboratory Medicine
DivisionAnatomic Pathology

TitleProfessor
InstitutionBoston University School of Public Health
DepartmentEpidemiology

TitleMentor for Graduate Medical Students
InstitutionBoston University School of Medicine, Division of Graduate Medical Sciences

TitleActive Staff Privileges
InstitutionBoston Medical Center
DepartmentPathology & Laboratory Medicine

 Research Expertise & Professional Interests
Expertise includes: Pathology of Gastrointestinal and liver diseases; Colorectal cancer screening and prevention; Molecular genetics of colorectal cancer and its precursors.

 Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Louis DN, O'Brien MJ, Young RH. The flowering of pathology as a medical discipline in Boston, 1892-c.1950: W.T. Councilman, FB Mallory, JH Wright, SB Wolbach and their descendants. Mod Pathol. 2016 Sep; 29(9):944-61. PMID: 27312063.
    View in: PubMed
  2. Herrera VL, Colby AH, Tan GA, Moran AM, O'Brien MJ, Colson YL, Ruiz-Opazo N, Grinstaff MW. Evaluation of expansile nanoparticle tumor localization and efficacy in a cancer stem cell-derived model of pancreatic peritoneal carcinomatosis. Nanomedicine (Lond). 2016 May; 11(9):1001-15. PMID: 27078118.
    View in: PubMed
  3. Shapiro MC, Wong B, O'Brien MJ, Salama A. Mandibular Destruction Secondary to Invasion by Carcinoma Cuniculatum. J Oral Maxillofac Surg. 2015 Dec; 73(12):2343-51. PMID: 26072180.
    View in: PubMed
  4. Schroy PC, Wong JB, O'Brien MJ, Chen CA, Griffith JL. A Risk Prediction Index for Advanced Colorectal Neoplasia at Screening Colonoscopy. Am J Gastroenterol. 2015 Jul; 110(7):1062-71. PMID: 26010311.
    View in: PubMed
  5. Yu H, Buch K, Li B, O'Brien M, Soto J, Jara H, Anderson SW. Utility of texture analysis for quantifying hepatic fibrosis on proton density MRI. J Magn Reson Imaging. 2015 Nov; 42(5):1259-65. PMID: 26477447.
    View in: PubMed
  6. Shaukat A, Church TR, Shanley R, Kauff ND, O'Brien MJ, Mills GM, Jordan PA, Allen JA, Kim A, Feld AD, Zauber AG, Winawer SJ. Development and validation of a clinical score for predicting risk of adenoma at screening colonoscopy. Cancer Epidemiol Biomarkers Prev. 2015 Jun; 24(6):913-20. PMID: 25800242.
    View in: PubMed
  7. O'Brien MJ, Zhao Q, Yang S. Colorectal serrated pathway cancers and precursors. Histopathology. 2015 Jan; 66(1):49-65. PMID: 25263173.
    View in: PubMed
  8. Qazi TM, O'Brien MJ, Farraye FA, Gould RW, Chen CA, Schroy PC. Epidemiology of goblet cell and microvesicular hyperplastic polyps. Am J Gastroenterol. 2014 Dec; 109(12):1922-32. PMID: 25350766.
    View in: PubMed
  9. Rodriguez-Diaz E, Huang Q, Cerda SR, O'Brien MJ, Bigio IJ, Singh SK. Endoscopic histological assessment of colonic polyps by using elastic scattering spectroscopy. Gastrointest Endosc. 2015 Mar; 81(3):539-47. PMID: 25257128.
    View in: PubMed
  10. O'Brien MJ, Meehan WP. Evaluating the risks and benefits of participation in high-school football. Virtual Mentor. 2014 Jul; 16(7):526-33. PMID: 25013917.
    View in: PubMed
  11. Lochhead P, Chan AT, Giovannucci E, Fuchs CS, Wu K, Nishihara R, O'Brien M, Ogino S. Progress and opportunities in molecular pathological epidemiology of colorectal premalignant lesions. Am J Gastroenterol. 2014 Aug; 109(8):1205-14. PMID: 24935274.
    View in: PubMed
  12. Rodriguez-Diaz E, Atkinson C, Jepeal LI, Berg A, Huang CS, Cerda SR, O'Brien MJ, Bigio IJ, Farraye FA, Singh SK. Elastic scattering spectroscopy as an optical marker of inflammatory bowel disease activity and subtypes. Inflamm Bowel Dis. 2014 Jun; 20(6):1029-36. PMID: 24798637.
    View in: PubMed
  13. Kim HJ, Boachie-Adjei O, Shaffrey CI, Schwab F, Lafage V, Bess S, Gupta MC, Smith JS, Deviren V, Akbarnia B, Mundis GM, O'Brien M, Hostin R, Ames C. Upper thoracic versus lower thoracic upper instrumented vertebrae endpoints have similar outcomes and complications in adult scoliosis. Spine (Phila Pa 1976). 2014 Jun 1; 39(13):E795-9. PMID: 24732840.
    View in: PubMed
  14. Drew DA, Devers TJ, O'Brien MJ, Horelik NA, Levine J, Rosenberg DW. HD chromoendoscopy coupled with DNA mass spectrometry profiling identifies somatic mutations in microdissected human proximal aberrant crypt foci. Mol Cancer Res. 2014 Jun; 12(6):823-9. PMID: 24651453.
    View in: PubMed
  15. Deshpande A, Nelson D, Corless CL, Deshpande V, O'Brien MJ. Leiomyoma of the gastrointestinal tract with interstitial cells of Cajal: a mimic of gastrointestinal stromal tumor. Am J Surg Pathol. 2014 Jan; 38(1):72-7. PMID: 24145645.
    View in: PubMed
  16. Anderson SW, Barry B, Soto J, Ozonoff A, O'Brien M, Jara H. Characterizing non-gaussian, high b-value diffusion in liver fibrosis: Stretched exponential and diffusional kurtosis modeling. J Magn Reson Imaging. 2014 Apr; 39(4):827-34. PMID: 24259401.
    View in: PubMed
  17. Hart R, McCarthy I, O'brien M, Bess S, Line B, Adjei OB, Burton D, Gupta M, Ames C, Deviren V, Kebaish K, Shaffrey C, Wood K, Hostin R. Identification of decision criteria for revision surgery among patients with proximal junctional failure after surgical treatment of spinal deformity. Spine (Phila Pa 1976). 2013 Sep 1; 38(19):E1223-7. PMID: 23778370.
    View in: PubMed
  18. Schroy PC, Coe A, Chen CA, O'Brien MJ, Heeren TC. Prevalence of advanced colorectal neoplasia in white and black patients undergoing screening colonoscopy in a safety-net hospital. Ann Intern Med. 2013 Jul 2; 159(1):13-20. PMID: 23817700.
    View in: PubMed
  19. Drew DA, Devers T, Horelik N, Yang S, O'Brien M, Wu R, Rosenberg DW. Nanoproteomic analysis of extracellular receptor kinase-1/2 post-translational activation in microdissected human hyperplastic colon lesions. Proteomics. 2013 May; 13(9):1428-36. PMID: 23467982.
    View in: PubMed
  20. Bennett M, Tompkins H, Seymour B, O'Brien MJ, Farraye FA. Spontaneous colonic perforation in a patient with collagenous colitis. Gastroenterol Hepatol (N Y). 2013 Apr; 9(4):262-4. PMID: 24711775.
    View in: PubMed
  21. Agarwal S, Stucchi AF, Dendrinos K, Cerda S, O'Brien MJ, Becker JM, Heeren T, Farraye FA. Is pyloric gland metaplasia in ileal pouch biopsies a marker for Crohn's disease? Dig Dis Sci. 2013 Oct; 58(10):2918-25. PMID: 23543088.
    View in: PubMed
  22. Gillespie E, Leeman SE, Watts LA, Coukos JA, O'Brien MJ, Cerda SR, Farraye FA, Stucchi AF. Plasminogen activator inhibitor-1 is increased in colonic epithelial cells from patients with colitis-associated cancer. J Crohns Colitis. 2013 Jun; 7(5):403-11. PMID: 22921465.
    View in: PubMed
  23. Anderson SW, Barry B, Soto JA, Ozonoff A, O'Brien M, Jara H. Quantifying hepatic fibrosis using a biexponential model of diffusion weighted imaging in ex vivo liver specimens. Magn Reson Imaging. 2012 Dec; 30(10):1475-82. PMID: 22921938.
    View in: PubMed
  24. Rex DK, Ahnen DJ, Baron JA, Batts KP, Burke CA, Burt RW, Goldblum JR, Guillem JG, Kahi CJ, Kalady MF, O'Brien MJ, Odze RD, Ogino S, Parry S, Snover DC, Torlakovic EE, Wise PE, Young J, Church J. Serrated lesions of the colorectum: review and recommendations from an expert panel. Am J Gastroenterol. 2012 Sep; 107(9):1315-29; quiz 1314, 1330. PMID: 22710576.
    View in: PubMed
  25. Scalera JE, Soto JA, Jara H, Ozonoff A, O'Brien M, Anderson SW. Multiexponential T(2) analyses in a murine model of hepatic fibrosis at 11.7 T MRI. NMR Biomed. 2013 Jan; 26(1):83-90. PMID: 22674663.
    View in: PubMed
  26. Zauber AG, Winawer SJ, O'Brien MJ, Lansdorp-Vogelaar I, van Ballegooijen M, Hankey BF, Shi W, Bond JH, Schapiro M, Panish JF, Stewart ET, Waye JD. Colonoscopic polypectomy and long-term prevention of colorectal-cancer deaths. N Engl J Med. 2012 Feb 23; 366(8):687-96. PMID: 22356322.
    View in: PubMed
  27. Anderson SW, Jara H, Ozonoff A, O'Brien M, Hamilton JA, Soto JA. Effect of disease progression on liver apparent diffusion coefficient and T2 values in a murine model of hepatic fibrosis at 11.7 Tesla MRI. J Magn Reson Imaging. 2012 Jan; 35(1):140-6. PMID: 21990020.
    View in: PubMed
  28. Gillespie E, Leeman SE, Watts LA, Coukos JA, O'Brien MJ, Cerda SR, Farraye FA, Stucchi AF, Becker JM. Truncated neurokinin-1 receptor is increased in colonic epithelial cells from patients with colitis-associated cancer. Proc Natl Acad Sci U S A. 2011 Oct 18; 108(42):17420-5. PMID: 21969570.
    View in: PubMed
  29. Winawer SJ, Krabshuis J, Lambert R, O'Brien M, Fried M. Cascade colorectal cancer screening guidelines: a global conceptual model. J Clin Gastroenterol. 2011 Apr; 45(4):297-300. PMID: 21301355.
    View in: PubMed
  30. Anderson SW, Soto JA, Milch HN, Ozonoff A, O'Brien M, Hamilton JA, Jara HJ. Effect of disease progression on liver apparent diffusion coefficient values in a murine model of NASH at 11.7 Tesla MRI. J Magn Reson Imaging. 2011 Apr; 33(4):882-8. PMID: 21448953.
    View in: PubMed
  31. Rex DK, Kahi C, O'Brien M, Levin TR, Pohl H, Rastogi A, Burgart L, Imperiale T, Ladabaum U, Cohen J, Lieberman DA. The American Society for Gastrointestinal Endoscopy PIVI (Preservation and Incorporation of Valuable Endoscopic Innovations) on real-time endoscopic assessment of the histology of diminutive colorectal polyps. Gastrointest Endosc. 2011 Mar; 73(3):419-22. PMID: 21353837.
    View in: PubMed
  32. Huang CS, Farraye FA, Yang S, O'Brien MJ. The clinical significance of serrated polyps. Am J Gastroenterol. 2011 Feb; 106(2):229-40; quiz 241. PMID: 21045813.
    View in: PubMed
  33. Hetzel JT, Huang CS, Coukos JA, Omstead K, Cerda SR, Yang S, O'Brien MJ, Farraye FA. Variation in the detection of serrated polyps in an average risk colorectal cancer screening cohort. Am J Gastroenterol. 2010 Dec; 105(12):2656-64. PMID: 20717107.
    View in: PubMed
  34. Lambert R, Kudo SE, Vieth M, Allen JI, Fujii H, Fujii T, Kashida H, Matsuda T, Mori M, Saito H, Shimoda T, Tanaka S, Watanabe H, Sung JJ, Feld AD, Inadomi JM, O'Brien MJ, Lieberman DA, Ransohoff DF, Soetikno RM, Zauber A, Teixeira CR, Rey JF, Jaramillo E, Rubio CA, Van Gossum A, Jung M, Jass JR, Triadafilopoulos G. Pragmatic classification of superficial neoplastic colorectal lesions. Gastrointest Endosc. 2009 Dec; 70(6):1182-99. PMID: 19879563.
    View in: PubMed
  35. Khalid O, Radaideh S, Cummings OW, O'Brien MJ, Goldblum JR, Rex DK. Reinterpretation of histology of proximal colon polyps called hyperplastic in 2001. World J Gastroenterol. 2009 Aug 14; 15(30):3767-70. PMID: 19673017.
    View in: PubMed
  36. Lambert R, O’Brien MJ, Jaramillo E, Vieth M. The serrated pathway to colorectal cancer. World Gastroenterology News. 2009; 14(2):5-11.
  37. Winawer SJ, O'Brien MJ . Management of Malignant Polyps. Chap 30, in Colonscopy, Principles and Practice,2nd Edition, Eds:Waye JD, Rex DK, Williams CB. Wiley-Blackwell. 2009; 401-412.
  38. Kovacheva VP, Davison JM, Mellott TJ, Rogers AE, Yang S, O'Brien MJ, Blusztajn JK. Raising gestational choline intake alters gene expression in DMBA-evoked mammary tumors and prolongs survival. FASEB J. 2009 Apr; 23(4):1054-63. PMID: 19047067.
    View in: PubMed
  39. Kudo Se, Lambert R, Allen JI, Fujii H, Fujii T, Kashida H, Matsuda T, Mori M, Saito H, Shimoda T, Tanaka S, Watanabe H, Sung JJ, Feld AD, Inadomi JM, O'Brien MJ, Lieberman DA, Ransohoff DF, Soetikno RM, Triadafilopoulos G, Zauber A, Teixeira CR, Rey JF, Jaramillo E, Rubio CA, Van Gossum A, Jung M, Vieth M, Jass JR, Hurlstone PD. Nonpolypoid neoplastic lesions of the colorectal mucosa. Gastrointest Endosc. 2008 Oct; 68(4 Suppl):S3-47. PMID: 18805238.
    View in: PubMed
  40. Kokkotou E, Espinoza DO, Torres D, Karagiannides I, Kosteletos S, Savidge T, O'Brien M, Pothoulakis C. Melanin-concentrating hormone (MCH) modulates C difficile toxin A-mediated enteritis in mice. Gut. 2009 Jan; 58(1):34-40. PMID: 18824554.
    View in: PubMed
  41. Kokkotou E, Moss AC, Torres D, Karagiannides I, Cheifetz A, Liu S, O'Brien M, Maratos-Flier E, Pothoulakis C. Melanin-concentrating hormone as a mediator of intestinal inflammation. Proc Natl Acad Sci U S A. 2008 Jul 29; 105(30):10613-8. PMID: 18650383.
    View in: PubMed
  42. Gay J, Kokkotou E, O'Brien M, Pothoulakis C, Karalis KP. Corticotropin-releasing hormone deficiency is associated with reduced local inflammation in a mouse model of experimental colitis. Endocrinology. 2008 Jul; 149(7):3403-9. PMID: 18403481.
    View in: PubMed
  43. Kokkotou E, Moss AC, Michos A, Espinoza D, Cloud JW, Mustafa N, O'Brien M, Pothoulakis C, Kelly CP. Comparative efficacies of rifaximin and vancomycin for treatment of Clostridium difficile-associated diarrhea and prevention of disease recurrence in hamsters. Antimicrob Agents Chemother. 2008 Mar; 52(3):1121-6. PMID: 18195066.
    View in: PubMed
  44. Huang CS, Farraye FA, O’Brien MJ . What is Hyperplastic Polyposis?. Curbside Consultation of the Colon, 49 Clinical Questions, Ed Cash BD, Farraye FA. Slack Inc. 2008; 39-44.
  45. Huang CS, Farraye FA, O’Brien MJ. What is a Serrated Adenoma and What do I tell my patients in terms of follow-up?. Curbside Consultation of the Colon, 49 Clinical Questions, Ed Cash BD, Farraye FA. Slack Inc. 2008; 45-47.
  46. O'Brien MJ. Hyperplastic and serrated polyps of the colorectum. Gastroenterol Clin North Am. 2007 Dec; 36(4):947-68, viii. PMID: 17996799.
    View in: PubMed
  47. Glatz K, Pritt B, Glatz D, Hartmann A, O'Brien MJ, Blaszyk H. A multinational, internet-based assessment of observer variability in the diagnosis of serrated colorectal polyps. Am J Clin Pathol. 2007 Jun; 127(6):938-45. PMID: 17509991.
    View in: PubMed
  48. Rosenberg DW, Yang S, Pleau DC, Greenspan EJ, Stevens RG, Rajan TV, Heinen CD, Levine J, Zhou Y, O'Brien MJ. Mutations in BRAF and KRAS differentially distinguish serrated versus non-serrated hyperplastic aberrant crypt foci in humans. Cancer Res. 2007 Apr 15; 67(8):3551-4. PMID: 17440063.
    View in: PubMed
  49. Katchar K, Kelly CP, Keates S, O'brien MJ, Keates AC. MIP-3alpha neutralizing monoclonal antibody protects against TNBS-induced colonic injury and inflammation in mice. Am J Physiol Gastrointest Liver Physiol. 2007 May; 292(5):G1263-71. PMID: 17272517.
    View in: PubMed
  50. Jass JR, O'Brien MJ, Riddell RH, Snover DC. Recommendations for the reporting of surgically resected specimens of colorectal carcinoma. Hum Pathol. 2007 Apr; 38(4):537-545. PMID: 17270246.
    View in: PubMed
  51. O'Brien MJ, Bloom A, LaBerge JM, Roberts JP, Rosenthal P, Kerlan RK. SIR 2006 Annual Meeting Film Panel Case: Budd-Chiari syndrome in a patient with Cogan syndrome. J Vasc Interv Radiol. 2006 Dec; 17(12):1881-3. PMID: 17185682.
    View in: PubMed
  52. O'Brien MJ, Yang S, Mack C, Xu H, Huang CS, Mulcahy E, Amorosino M, Farraye FA. Comparison of microsatellite instability, CpG island methylation phenotype, BRAF and KRAS status in serrated polyps and traditional adenomas indicates separate pathways to distinct colorectal carcinoma end points. Am J Surg Pathol. 2006 Dec; 30(12):1491-501. PMID: 17122504.
    View in: PubMed
  53. Jass JR, O'Brien MJ, Riddell RH, Snover DC. Recommendations for the reporting of surgically resected specimens of colorectal carcinoma. Virchows Arch. 2007 Jan; 450(1):1-13. PMID: 17334800.
    View in: PubMed
  54. Gay J, Kokkotou E, O'Brien M, Pothoulakis C, Karalis KP. Interleukin-6 genetic ablation protects from trinitrobenzene sulfonic acid-induced colitis in mice. Putative effect of antiinflammatory cytokines. Neuroimmunomodulation. 2006; 13(2):114-21. PMID: 17077645.
    View in: PubMed
  55. Kokkotou E, Torres D, Moss AC, O'Brien M, Grigoriadis DE, Karalis K, Pothoulakis C. Corticotropin-releasing hormone receptor 2-deficient mice have reduced intestinal inflammatory responses. J Immunol. 2006 Sep 1; 177(5):3355-61. PMID: 16920976.
    View in: PubMed
  56. Stucchi A, Reed K, O'Brien M, Cerda S, Andrews C, Gower A, Bushell K, Amar S, Leeman S, Becker J. A new transcription factor that regulates TNF-alpha gene expression, LITAF, is increased in intestinal tissues from patients with CD and UC. Inflamm Bowel Dis. 2006 Jul; 12(7):581-7. PMID: 16804395.
    View in: PubMed
  57. Chen X, Kokkotou EG, Mustafa N, Bhaskar KR, Sougioultzis S, O'Brien M, Pothoulakis C, Kelly CP. Saccharomyces boulardii inhibits ERK1/2 mitogen-activated protein kinase activation both in vitro and in vivo and protects against Clostridium difficile toxin A-induced enteritis. J Biol Chem. 2006 Aug 25; 281(34):24449-54. PMID: 16816386.
    View in: PubMed
  58. Winawer SJ, Zauber AG, Fletcher RH, Stillman JS, O'brien MJ, Levin B, Smith RA, Lieberman DA, Burt RW, Levin TR, Bond JH, Brooks D, Byers T, Hyman N, Kirk L, Thorson A, Simmang C, Johnson D, Rex DK. Guidelines for colonoscopy surveillance after polypectomy: a consensus update by the US Multi-Society Task Force on Colorectal Cancer and the American Cancer Society. CA Cancer J Clin. 2006 May-Jun; 56(3):143-59; quiz 184-5. PMID: 16737947.
    View in: PubMed
  59. Rex DK, Kahi CJ, Levin B, Smith RA, Bond JH, Brooks D, Burt RW, Byers T, Fletcher RH, Hyman N, Johnson D, Kirk L, Lieberman DA, Levin TR, O'Brien MJ, Simmang C, Thorson AG, Winawer SJ. Guidelines for colonoscopy surveillance after cancer resection: a consensus update by the American Cancer Society and US Multi-Society Task Force on Colorectal Cancer. CA Cancer J Clin. 2006 May-Jun; 56(3):160-7; quiz 185-6. PMID: 16737948.
    View in: PubMed
  60. Rex DK, Kahi CJ, Levin B, Smith RA, Bond JH, Brooks D, Burt RW, Byers T, Fletcher RH, Hyman N, Johnson D, Kirk L, Lieberman DA, Levin TR, O'Brien MJ, Simmang C, Thorson AG, Winawer SJ. Guidelines for colonoscopy surveillance after cancer resection: a consensus update by the American Cancer Society and the US Multi-Society Task Force on Colorectal Cancer. Gastroenterology. 2006 May; 130(6):1865-71. PMID: 16697749.
    View in: PubMed
  61. Winawer SJ, Zauber AG, Fletcher RH, Stillman JS, O'Brien MJ, Levin B, Smith RA, Lieberman DA, Burt RW, Levin TR, Bond JH, Brooks D, Byers T, Hyman N, Kirk L, Thorson A, Simmang C, Johnson D, Rex DK. Guidelines for colonoscopy surveillance after polypectomy: a consensus update by the US Multi-Society Task Force on Colorectal Cancer and the American Cancer Society. Gastroenterology. 2006 May; 130(6):1872-85. PMID: 16697750.
    View in: PubMed
  62. Karagiannides I, Kokkotou E, Tansky M, Tchkonia T, Giorgadze N, O'Brien M, Leeman SE, Kirkland JL, Pothoulakis C. Induction of colitis causes inflammatory responses in fat depots: evidence for substance P pathways in human mesenteric preadipocytes. Proc Natl Acad Sci U S A. 2006 Mar 28; 103(13):5207-12. PMID: 16549770.
    View in: PubMed
  63. Yantiss RK, Farraye FA, O'Brien MJ, Fruin AB, Stucchi AF, Becker JM, Reddy SI, Odze RD. Prognostic significance of superficial fissuring ulceration in patients with severe "indeterminate" colitis. Am J Surg Pathol. 2006 Feb; 30(2):165-70. PMID: 16434889.
    View in: PubMed
  64. Nunes D, Fleming C, Offner G, O'Brien M, Tumilty S, Fix O, Heeren T, Koziel M, Graham C, Craven DE, Stuver S, Horsburgh CR. HIV infection does not affect the performance of noninvasive markers of fibrosis for the diagnosis of hepatitis C virus-related liver disease. J Acquir Immune Defic Syndr. 2005 Dec 15; 40(5):538-44. PMID: 16284529.
    View in: PubMed
  65. Reed KL, Fruin AB, Gower AC, Gonzales KD, Stucchi AF, Andry CD, O'Brien M, Becker JM. NF-kappaB activation precedes increases in mRNA encoding neurokinin-1 receptor, proinflammatory cytokines, and adhesion molecules in dextran sulfate sodium-induced colitis in rats. Dig Dis Sci. 2005 Dec; 50(12):2366-78. PMID: 16416193.
    View in: PubMed
  66. Rhee SH, Im E, Riegler M, Kokkotou E, O'brien M, Pothoulakis C. Pathophysiological role of Toll-like receptor 5 engagement by bacterial flagellin in colonic inflammation. Proc Natl Acad Sci U S A. 2005 Sep 20; 102(38):13610-5. PMID: 16157881.
    View in: PubMed
  67. Huang CS, O'brien MJ, Yang S, Farraye FA. Hyperplastic polyps, serrated adenomas, and the serrated polyp neoplasia pathway. Am J Gastroenterol. 2004 Nov; 99(11):2242-55. PMID: 15555008.
    View in: PubMed
  68. Yang S, Farraye FA, Mack C, Posnik O, O'Brien MJ. BRAF and KRAS Mutations in hyperplastic polyps and serrated adenomas of the colorectum: relationship to histology and CpG island methylation status. Am J Surg Pathol. 2004 Nov; 28(11):1452-9. PMID: 15489648.
    View in: PubMed
  69. O'brien MJ, Winawer SJ, Zauber AG, Bushey MT, Sternberg SS, Gottlieb LS, Bond JH, Waye JD, Schapiro M. Flat adenomas in the National Polyp Study: is there increased risk for high-grade dysplasia initially or during surveillance? Clin Gastroenterol Hepatol. 2004 Oct; 2(10):905-11. PMID: 15476154.
    View in: PubMed
  70. Anton PM, O'Brien M, Kokkotou E, Eisenstein B, Michaelis A, Rothstein D, Paraschos S, Kelly CP, Pothoulakis C. Rifalazil treats and prevents relapse of clostridium difficile-associated diarrhea in hamsters. Antimicrob Agents Chemother. 2004 Oct; 48(10):3975-9. PMID: 15388461.
    View in: PubMed
  71. Yantiss RK, Sapp HL, Farraye FA, El-Zammar O, O'Brien MJ, Fruin AB, Stucchi AF, Brien TP, Becker JM, Odze RD. Histologic predictors of pouchitis in patients with chronic ulcerative colitis. Am J Surg Pathol. 2004 Aug; 28(8):999-1006. PMID: 15252305.
    View in: PubMed
  72. Anton PM, Gay J, Mykoniatis A, Pan A, O'Brien M, Brown D, Karalis K, Pothoulakis C. Corticotropin-releasing hormone (CRH) requirement in Clostridium difficile toxin A-mediated intestinal inflammation. Proc Natl Acad Sci U S A. 2004 Jun 1; 101(22):8503-8. PMID: 15159534.
    View in: PubMed
  73. O'Brien MJ, Yang S, Clebanoff JL, Mulcahy E, Farraye FA, Amorosino M, Swan N. Hyperplastic (serrated) polyps of the colorectum: relationship of CpG island methylator phenotype and K-ras mutation to location and histologic subtype. Am J Surg Pathol. 2004 Apr; 28(4):423-34. PMID: 15087661.
    View in: PubMed
  74. Pistey RW, O'Brien MJ. Digital Imaging...Ready for Prime Time. Laboratory Medicine. 2004; 35:87-91.
  75. Savidge TC, Pan WH, Newman P, O'brien M, Anton PM, Pothoulakis C. Clostridium difficile toxin B is an inflammatory enterotoxin in human intestine. Gastroenterology. 2003 Aug; 125(2):413-20. PMID: 12891543.
    View in: PubMed
  76. Stucchi AF, Shebani KO, Leeman SE, Wang CC, Reed KL, Fruin AB, Gower AC, McClung JP, Andry CD, O'Brien MJ, Pothoulakis C, Becker JM. A neurokinin 1 receptor antagonist reduces an ongoing ileal pouch inflammation and the response to a subsequent inflammatory stimulus. Am J Physiol Gastrointest Liver Physiol. 2003 Dec; 285(6):G1259-67. PMID: 12893626.
    View in: PubMed
  77. Fruin AB, El-Zammer O, Stucchi AF, O'Brien M, Becker JM. Colonic metaplasia in the ileal pouch is associated with inflammation and is not the result of long-term adaptation. J Gastrointest Surg. 2003 Feb; 7(2):246-53; discussion 253-4. PMID: 12600449.
    View in: PubMed
  78. Winawer SJ, O'Brien MJ . Management of Malignant Polyps. In Colonoscopy: Principles and Practice. Waye JD, Rex DK, Williams CB, Ed. Blackwell, Inc. London,UK. 2003; 448-449.
  79. Zauber AG, O'Brien MJ, Winawer SJ. On finding flat adenomas: is the search worth the gain? Gastroenterology. 2002 Mar; 122(3):839-40. PMID: 11878297.
    View in: PubMed
  80. Tendler DA, Aboudola S, Zacks JF, O'Brien MJ, Kelly CP. Prolapsing mucosal polyps: an underrecognized form of colonic polyp--a clinicopathological study of 15 cases. Am J Gastroenterol. 2002 Feb; 97(2):370-6. PMID: 11866275.
    View in: PubMed
  81. Patriquin L, Kassarjian A, Barish M, Casserley L, O'Brien M, Andry C, Eustace S. Postmortem whole-body magnetic resonance imaging as an adjunct to autopsy: preliminary clinical experience. J Magn Reson Imaging. 2001 Feb; 13(2):277-87. PMID: 11169835.
    View in: PubMed
  82. Stucchi AF, Shofer S, Leeman S, Materne O, Beer E, McClung J, Shebani K, Moore F, O'Brien M, Becker JM. NK-1 antagonist reduces colonic inflammation and oxidative stress in dextran sulfate-induced colitis in rats. Am J Physiol Gastrointest Liver Physiol. 2000 Dec; 279(6):G1298-306. PMID: 11093954.
    View in: PubMed
  83. O'Brien MJ, Keating NM, Elderiny S, Cerda S, Keaveny AP, Afdhal NH, Nunes DP. An assessment of digital image analysis to measure fibrosis in liver biopsy specimens of patients with chronic hepatitis C. Am J Clin Pathol. 2000 Nov; 114(5):712-8. PMID: 11068544.
    View in: PubMed
  84. Shie JL, Chen ZY, O'Brien MJ, Pestell RG, Lee ME, Tseng CC. Role of gut-enriched Krüppel-like factor in colonic cell growth and differentiation. Am J Physiol Gastrointest Liver Physiol. 2000 Oct; 279(4):G806-14. PMID: 11005769.
    View in: PubMed
  85. Winawer SJ, Stewart ET, Zauber AG, Bond JH, Ansel H, Waye JD, Hall D, Hamlin JA, Schapiro M, O'Brien MJ, Sternberg SS, Gottlieb LS. A comparison of colonoscopy and double-contrast barium enema for surveillance after polypectomy. National Polyp Study Work Group. N Engl J Med. 2000 Jun 15; 342(24):1766-72. PMID: 10852998.
    View in: PubMed
  86. Mulligan NJ, Yang S, Andry C, Klein M, O'Brien MJ. The role of p21ras in pancreatic neoplasia and chronic pancreatitis. Hum Pathol. 1999 Jun; 30(6):602-10. PMID: 10374765.
    View in: PubMed
  87. Mulligan NJ, de las Morenas A, Soto-Wright V, O'Brien MJ. Percentages of cervical cytologic diagnoses as a quality assurance method. Acta Cytol. 1998 Jul-Aug; 42(4):928-32. PMID: 9684579.
    View in: PubMed
  88. Zacks JF, de las Morenas A, Beazley RM, O'Brien MJ. Fine-needle aspiration cytology diagnosis of colloid nodule versus follicular variant of papillary carcinoma of the thyroid. Diagn Cytopathol. 1998 Feb; 18(2):87-90. PMID: 9484634.
    View in: PubMed
  89. O'Brien MJ, Takahashi M, Brugal G, Christen H, Gahm T, Goodell RM, Karakitsos P, Knesel EA, Kobler T, Kyrkou KA, Labbe S, Long EL, Mango LJ, McGoogan E, Oberholzer M, Reith A, Winkler C. Digital imagery/telecytology. International Academy of Cytology Task Force summary. Diagnostic Cytology Towards the 21st Century: An International Expert Conference and Tutorial. Acta Cytol. 1998 Jan-Feb; 42(1):148-64. PMID: 9479334.
    View in: PubMed
  90. Afdhal NH, Keaveny AP, Cohen SB, Nunes DP, Maldonado N, O'Brien M, Stone PJ. Urinary assays for desmosine and hydroxylysylpyridinoline in the detection of cirrhosis. J Hepatol. 1997 Dec; 27(6):993-1002. PMID: 9453424.
    View in: PubMed
  91. Fogt F, Nikulasson ST, Holden JA, Alder SA, Hallgrimsson J, Jessup MJ, O'Brien MJ, Lavin PT, Goldman H. Topoisomerase II alpha expression in normal, inflammatory, and neoplastic conditions of the gastric and colonic mucosa. Mod Pathol. 1997 Apr; 10(4):296-302. PMID: 9110290.
    View in: PubMed
  92. Mac Mathuna P, Siegenberg D, Gibbons D, Gorin D, O'Brien M, Afdhal NA, Chuttani R. The acute and long-term effect of balloon sphincteroplasty on papillary structure in pigs. Gastrointest Endosc. 1996 Dec; 44(6):650-5. PMID: 8979052.
    View in: PubMed
  93. O'Brien MJ, Sotnikov AV. Digital imaging in anatomic pathology. Am J Clin Pathol. 1996 Oct; 106(4 Suppl 1):S25-32. PMID: 8853053.
    View in: PubMed
  94. O'Brien MJ, Gibbons D. The adenoma-carcinoma sequence in colorectal neoplasia. Surg Oncol Clin N Am. 1996 Jul; 5(3):513-30. PMID: 8829316.
    View in: PubMed
  95. Celen O, O'Brien MJ, Melby JC, Beazley RM. Factors influencing outcome of surgery for primary aldosteronism. Arch Surg. 1996 Jun; 131(6):646-50. PMID: 8645073.
    View in: PubMed
  96. Winawer SJ, St John DJ, Bond JH, Rozen P, Burt RW, Waye JD, Kronborg O, O'Brien MJ, Bishop DT, Kurtz RC, Shike M, Swaroop SV, Levin B, Frühmorgen P, Lynch HT. [Prevention of colorectal carcinoma. Current WHO guidelines for early detection of colorectal carcinoma. World Health Organization Collaborating Center for the Prevention of Colorectal Cancer]. Leber Magen Darm. 1996 May; 26(3):139-40, 143. PMID: 8709827.
    View in: PubMed
  97. Winawer SJ, Zauber AG, Gerdes H, O'Brien MJ, Gottlieb LS, Sternberg SS, Bond JH, Waye JD, Schapiro M, Panish JF, et al. Risk of colorectal cancer in the families of patients with adenomatous polyps. National Polyp Study Workgroup. N Engl J Med. 1996 Jan 11; 334(2):82-7. PMID: 8531963.
    View in: PubMed
  98. Association of Directors of Anatomic Pathology. Recommendations for Reporting of Resected Large Intestinal Carcinomas. Hum. Pathol. 1996; 27:5-8.
  99. Winawer SJ, St John DJ, Bond JH, Rozen P, Burt RW, Waye JD, Kronborg O, O'Brien MJ, Bishop DT, Kurtz RC, et al. Guidelines for the prevention of colorectal cancer: update based on new data. World Health Organization Collaborating Center for the Prevention of Colorectal Cancer. Z Gastroenterol. 1995 Sep; 33(9):574-6. PMID: 8525666.
    View in: PubMed
  100. Schroy PC, Brown-Shimer S, Kim K, Johnson KA, Murnane MJ, Yang S, O'Brien MJ, Carney WP, Kupchik HZ. Detection of p21ras mutations in colorectal adenomas and carcinomas by enzyme-linked immunosorbent assay. Cancer. 1995 Jul 15; 76(2):201-9. PMID: 8625092.
    View in: PubMed
  101. Winawer SJ, St John DJ, Bond JH, Rozen P, Burt RW, Waye JD, Kronborg O, O'Brien MJ, Bishop DT, Kurtz RC, et al. Prevention of colorectal cancer: guidelines based on new data. WHO Collaborating Center for the Prevention of Colorectal Cancer. Bull World Health Organ. 1995; 73(1):7-10. PMID: 7704928.
    View in: PubMed
  102. Waye JD, O’Brien MJ . Cancer in Polyps. Cancer of the Colon, Rectum and Anus. Eds. Cohen A, Winawer S. McGraw-Hill. 1994.
  103. O’Brien MJ . Colorectal Polyps in Cancer of the Colon, Rectum and Anus. Eds. Cohen A, Winawer S. McGraw-Hill,. 1994.
  104. Winawer SJ, Zauber AG, Ho MN, O'Brien MJ, Gottlieb LS, Sternberg SS, Waye JD, Schapiro M, Bond JH, Panish JF, et al. Prevention of colorectal cancer by colonoscopic polypectomy. The National Polyp Study Workgroup. N Engl J Med. 1993 Dec 30; 329(27):1977-81. PMID: 8247072.
    View in: PubMed
  105. Sheahan K, O'Keane JC, Abramowitz A, Carlson JA, Burke B, Gottlieb LS, O'Brien MJ. Metastatic adenocarcinoma of an unknown primary site. A comparison of the relative contributions of morphology, minimal essential clinical data and CEA immunostaining status. Am J Clin Pathol. 1993 Jun; 99(6):729-35. PMID: 8322709.
    View in: PubMed
  106. Winawer SJ, Zauber AG, Ho MN, O'Brien MJ, Gottlieb LS, Sternberg SS, Stewart ET, Bond JH, Schapiro M, Panish JF, et al. The National Polyp Study. Eur J Cancer Prev. 1993 Jun; 2 Suppl 2:83-7. PMID: 8364377.
    View in: PubMed
  107. Kline TJ, De las Morenas T, O'Brien M, Smith BF, Afdhal NH. Squamous metaplasia of extrahepatic biliary system in an AIDS patient with cryptosporidia and cholangitis. Dig Dis Sci. 1993 May; 38(5):960-2. PMID: 8482197.
    View in: PubMed
  108. Winawer SJ, Zauber AG, O'Brien MJ, Ho MN, Gottlieb L, Sternberg SS, Waye JD, Bond J, Schapiro M, Stewart ET, et al. Randomized comparison of surveillance intervals after colonoscopic removal of newly diagnosed adenomatous polyps. The National Polyp Study Workgroup. N Engl J Med. 1993 Apr 1; 328(13):901-6. PMID: 8446136.
    View in: PubMed
  109. Fisher ER, Anderson S, Redmond C, Fisher B, Anzola E, Beecher T, Lomotan A, Newkirk R, Bennett B, Shrago S, Kingsley WB, Glenn G, O’Brien MJ, Wotiz H, Ainsworth AM, DePillis VJ, Rowand CW, Strumis P, Watts H, et al . Pathology findings from the National Surgical Adjuvant Breast Project protocol B-06: 10-year pathologic and clinical prognostic discriminants. Cancer. 1993; 2507-2514.
  110. O'Keane JC, Stahl D, Sheahan K, Burke B, Gottlieb LS, O'Brien MJ. Analysis of epithelial and lymphoid phenotypic markers in relation to growth pattern of colorectal adenomas. Hum Pathol. 1992 Sep; 23(9):1038-43. PMID: 1381333.
    View in: PubMed
  111. Winawer SJ, Zauber AG, O'Brien MJ, Gottlieb LS, Sternberg SS, Stewart ET, Bond JH, Schapiro M, Panish JF, Waye JD, et al. The National Polyp Study. Design, methods, and characteristics of patients with newly diagnosed polyps. The National Polyp Study Workgroup. Cancer. 1992 Sep 1; 70(5 Suppl):1236-45. PMID: 1511370.
    View in: PubMed
  112. O'Brien MJ, O'Keane JC, Zauber A, Gottlieb LS, Winawer SJ. Precursors of colorectal carcinoma. Biopsy and biologic markers. Cancer. 1992 Sep 1; 70(5 Suppl):1317-27. PMID: 1511379.
    View in: PubMed
  113. O'Brien MJ, Waye JD, Winawer SJ . Colorectal Polyps. Chapter 22, in Management of Gastrointestinal Diseases. Ed Winawer SJ(ed). Gower Inc. New York,NY. 1992.
  114. O'Brien MJ, O'Keane JC, Gottlieb LS, Zauber AG, Winawer SJ. Adenoma Progression to Carcinoma: Classification of Phenotypic Changes. in Rossini FR et al(eds): Recent Progree in Colorectal Cancer: Biology and Management of High-Risk Groups. Elsevier. Amsterdam. 1992; 59-65.
  115. O'Brien MJ, Waye JD, Winawer SJ . Colorectal Polyps. Chapter 3, in Gastrointestinal Cancer, Winawer SJ, Kurtz RC (eds). Gower. New York,NY. 1992.
  116. Winawer SJ, O'Brien MJ, Waye JD, Shike M, Kurtz RC, Schapiro M . Surveillance Following Polypectomy. In: Rossini FP, Lynch HT, Winawer SJ. In: Recent Progress in Colorectal Cancer: Biology and Management of High Risk Groups. Elsevier Science Publishers, B.V. Amsterdam. 1992; 83-88.
  117. Lee VW, Fuller JD, O'Brien MJ, Parker DR, Cooley TP, Liebman HA. Pulmonary Kaposi sarcoma in patients with AIDS: scintigraphic diagnosis with sequential thallium and gallium scanning. Radiology. 1991 Aug; 180(2):409-12. PMID: 2068302.
    View in: PubMed
  118. Winawer SJ, Zauber AG, Stewart E, O'Brien MJ. The natural history of colorectal cancer. Opportunities for intervention. Cancer. 1991 Feb 15; 67(4 Suppl):1143-9. PMID: 1991272.
    View in: PubMed
  119. O'Keane JC, Kupchik HZ, Schroy PC, Andry CD, Collins E, O'Brien MJ. A three-dimensional system for long-term culture of human colorectal adenomas. Am J Pathol. 1990 Dec; 137(6):1539-47. PMID: 2260636.
    View in: PubMed
  120. Loftus BM, Gilmartin LG, O'Brien MJ, Carney DN, Dervan PA. Intratubular germ cell neoplasia of the testis: identification by placental alkaline phosphatase immunostaining and argyrophilic nucleolar organizer region quantification. Hum Pathol. 1990 Sep; 21(9):941-8. PMID: 1697556.
    View in: PubMed
  121. Sheahan K, O'Brien MJ, Burke B, Dervan PA, O'Keane JC, Gottlieb LS, Zamcheck N. Differential reactivities of carcinoembryonic antigen (CEA) and CEA-related monoclonal and polyclonal antibodies in common epithelial malignancies. Am J Clin Pathol. 1990 Aug; 94(2):157-64. PMID: 1695478.
    View in: PubMed
  122. Kupchik HZ, Collins EA, O'Brien MJ, McCaffrey RP. Chemotherapy screening assay using 3-dimensional cell culture. Cancer Lett. 1990 May 15; 51(1):11-6. PMID: 2337892.
    View in: PubMed
  123. O'Keane JC, Okon E, Moroz K, Burke B, Sheahan K, O'Brien MJ. Anti-estradiol immunoperoxidase labeling of nuclei, not cytoplasm, in paraffin sections, determines estrogen receptor status of breast cancer. Am J Surg Pathol. 1990 Feb; 14(2):121-7. PMID: 2154140.
    View in: PubMed
  124. O'Brien MJ, Winawer SJ, Zauber AG, Gottlieb LS, Sternberg SS, Diaz B, Dickersin GR, Ewing S, Geller S, Kasimian D, et al. The National Polyp Study. Patient and polyp characteristics associated with high-grade dysplasia in colorectal adenomas. Gastroenterology. 1990 Feb; 98(2):371-9. PMID: 2403953.
    View in: PubMed
  125. Winawer SJ, O'Brien MJ, Waye JD, Kronborg O, Bond J, Frühmorgen P, Sobin LH, Burt R, Zauber A, Morson B. Risk and surveillance of individuals with colorectal polyps. Who Collaborating Centre for the Prevention of Colorectal Cancer. Bull World Health Organ. 1990; 68(6):789-95. PMID: 2073716.
    View in: PubMed
  126. Johnston PG, O'Brien MJ, Dervan PA, Carney DN. Immunohistochemical analysis of cell kinetic parameters in colonic adenocarcinomas, adenomas, and normal mucosa. Hum Pathol. 1989 Jul; 20(7):696-700. PMID: 2661411.
    View in: PubMed
  127. Dervan PA, Tobbia IN, Casey M, O'Loughlin J, O'Brien M. Glomus tumours: an immunohistochemical profile of 11 cases. Histopathology. 1989 May; 14(5):483-91. PMID: 2544504.
    View in: PubMed
  128. O'Brien MJ, Winawer SJ, Zauber A, Diaz B, Gottlieb LS, Bond J, Geenen J, Hogan W, Panish JF, Waye JD, Schapiro M and the National Polyp Study Workgroup . The United States National Polyp Study. In Accomplishments in Oncology. JB Lippincott. 1989; 3: 7:211-224.
  129. Bulger K, O'Riordan M, Purdy S, O'Brien M, Lennon J. Gastrointestinal sarcoidosis resembling Crohn's disease. Am J Gastroenterol. 1988 Dec; 83(12):1415-7. PMID: 3195549.
    View in: PubMed
  130. Bulger K, Griffin M, O'Brien M, Crowe J. Lymphoma in the mesenteric lymph node cavitation syndrome. Gastroenterology. 1988 Feb; 94(2):553. PMID: 3335328.
    View in: PubMed
  131. Winawer SJ, Gottlieb LS, O'Brien MJ, et al . The National Polyp Study: An Overview and Preliminary Report. In Basic and Clinical Perspective of Colorectal Polyps. Karr JP, Ed. Alan R Liss, Inc. New York,NY. 1988; 35-49.
  132. Winawer SJ, Zauber A, Diaz B, O'Brien M, Gottlieb LS, Sternberg SS, Waye JD, Shike M. The National Polyp Study: overview of program and preliminary report of patient and polyp characteristics. Prog Clin Biol Res. 1988; 279:35-49. PMID: 3054929.
    View in: PubMed
  133. Murray FE, O'Brien MJ, Birkett DH, Kennedy SM, LaMont JT. Diversion colitis. Pathologic findings in a resected sigmoid colon and rectum. Gastroenterology. 1987 Dec; 93(6):1404-8. PMID: 3678755.
    View in: PubMed
  134. Spigelman Z, Dowers A, Kennedy S, DiSorbo D, O'Brien M, Barr R, McCaffrey R. Antiproliferative effects of suramin on lymphoid cells. Cancer Res. 1987 Sep 1; 47(17):4694-8. PMID: 3621163.
    View in: PubMed
  135. Triadafilopoulos G, Pothoulakis C, O'Brien MJ, LaMont JT. Differential effects of Clostridium difficile toxins A and B on rabbit ileum. Gastroenterology. 1987 Aug; 93(2):273-9. PMID: 3596162.
    View in: PubMed
  136. Brady K, Page DV, Benn LE, de las Morenas A, O'Brien M. Ovarian myxoma. Am J Obstet Gynecol. 1987 May; 156(5):1240-2. PMID: 3555091.
    View in: PubMed
  137. el-Deriny SE, O'Brien MJ, Christensen TG, Kupchik HZ. Ultrastructural differentiation and CEA expression of butyrate-treated human pancreatic carcinoma cells. Pancreas. 1987; 2(1):25-33. PMID: 3575313.
    View in: PubMed
  138. Primrose WJ, McDonald GA, O'Brien MJ, Vaughan CW, Strong MS. Synergistic effects of sequential carbon dioxide and neodymium:yttrium aluminum garnet laser injuries. Experimental observations and measurements. Ann Otol Rhinol Laryngol. 1987 Jan-Feb; 96(1 Pt 1):47-52. PMID: 3545019.
    View in: PubMed
  139. Niles RM, Wilhelm SA, Steele GD, Burke B, Christensen T, Dexter D, O'Brien MJ, Thomas P, Zamcheck N. Isolation and characterization of an undifferentiated human colon carcinoma cell line (MIP-101). Cancer Invest. 1987; 5(6):545-52. PMID: 3442732.
    View in: PubMed
  140. Pietrafitta JJ, Anderson BG, O'Brien MJ, Deckers PJ. Cholecystitis secondary to infusion chemotherapy. J Surg Oncol. 1986 Apr; 31(4):287-93. PMID: 2941626.
    View in: PubMed
  141. Lee VW, Peng TT, O'Brien MJ, Hauck RM. Budd-Chiari syndrome complicating hepatocellular carcinoma. Demonstration by multiple radiotracer scintigraphy. Clin Nucl Med. 1986 Feb; 11(2):102-7. PMID: 3021372.
    View in: PubMed
  142. Lee VW, O'Brien MJ, Morris PM, Devereux DF, Shapiro JH. The specific diagnosis of hepatocellular carcinoma by scintigraphy. Multiple radiotracer approach. Cancer. 1985 Jul 1; 56(1):25-36. PMID: 2988735.
    View in: PubMed
  143. Lee VW, O'Brien MJ, Devereux DF, Morris PM, Shapiro JH. Hepatocellular carcinoma: uptake of 99mTc-IDA in primary tumor and metastasis. AJR Am J Roentgenol. 1984 Jul; 143(1):57-61. PMID: 6328961.
    View in: PubMed
  144. Tracey KJ, O'Brien MJ, Williams LF, Klibaner M, George PK, Saravis CA, Zamcheck N. Signet ring carcinoma of the pancreas, a rare variant with very high CEA values. Immunohistologic comparison with adenocarcinoma. Dig Dis Sci. 1984 Jun; 29(6):573-6. PMID: 6327210.
    View in: PubMed
  145. Devereux DF, Kavanah MT, Feldman MI, Kondi E, Hull D, O'Brien M, Deckers PJ, Mozden PJ. Small bowel exclusion from the pelvis by a polyglycolic acid mesh sling. J Surg Oncol. 1984 Jun; 26(2):107-12. PMID: 6330456.
    View in: PubMed
  146. Dayal Y, Doos WG, O'Brien MJ, Nunnemacher G, DeLellis RA, Wolfe HJ. Psammomatous somatostatinomas of the duodenum. Am J Surg Pathol. 1983 Oct; 7(7):653-65. PMID: 6139028.
    View in: PubMed
  147. Kupchik HZ, Langer RS, Haberern C, El Deriny S, O'Brien M. A new method for the three-dimensional in vitro growth of human cancer cells. Exp Cell Res. 1983 Sep; 147(2):454-60. PMID: 6352294.
    View in: PubMed
  148. Goslin RH, O'Brien MJ, Skarin AT, Zamcheck N. Immunocytochemical staining for CEA in small cell carcinoma of lung predicts clinical usefulness of the plasma assay. Cancer. 1983 Jul 15; 52(2):301-6. PMID: 6305471.
    View in: PubMed
  149. deVere White R, O'Brien M, Krikorian J, Babayan R, Olsson CA. Maytansine as a cause of acute proliferative disorder of bladder urothelium in the rat. Cancer Treat Rep. 1983 Feb; 67(2):183-4. PMID: 6825127.
    View in: PubMed
  150. Rau P, O'Brien M, Ezpeleta M, Williams L, Kramer P, Burakoff R. Bleeding Meckel's diverticulum in a patient with inflammatory bowel disease. J Clin Gastroenterol. 1982 Oct; 4(5):455-9. PMID: 6983539.
    View in: PubMed
  151. George PK, Loewenstein MS, O'Brien MJ, Bronstein B, Koff RS, Zamcheck N. Circulating CEA levels in patients with fulminant hepatitis. Dig Dis Sci. 1982 Feb; 27(2):139-42. PMID: 7075408.
    View in: PubMed
  152. Laffal LD, Bond JH, Decosse JJ, O'Brien MJ . Colorectal Cancer, Surgical Management, Clinical Roundtables. 1982; 15:1-8.
  153. Goslin R, O'Brien MJ, Steele G, Mayer R, Wilson R, Corson JM, Zamcheck N. Correlation of Plasma CEA and CEA tissue staining in poorly differentiated colorectal cancer. Am J Med. 1981 Aug; 71(2):246-53. PMID: 6167166.
    View in: PubMed
  154. O'Brien MJ, Zamcheck N, Burke B, Kirkham SE, Saravis CA, Gottlieb LS. Immunocytochemical localization of carcinoembryonic antigen in benign and malignant colorectal tissues. Assessment of diagnostic value. Am J Clin Pathol. 1981 Mar; 75(3):283-90. PMID: 7010989.
    View in: PubMed
  155. O'Brien MJ, Kirkham SE, Burke B, Ormerod M, Saravis CA, Gottlieb LS, Neville AM, Zamcheck N. CEA, ZGM and EMA localization in cells of pleural and peritoneal effusion: a preliminary study. Invest Cell Pathol. 1980 Jul-Sep; 3(3):251-8. PMID: 6159337.
    View in: PubMed
  156. O'Brien MJ, Bronstein B, Zamcheck N, Saravis C, Burke B, Gottlieb LS. Cholestasis and hepatic metastases: a factor contributing to extreme elevations of carcinoembryonic antigen. J Natl Cancer Inst. 1980 Jun; 64(6):1291-4. PMID: 6246298.
    View in: PubMed
  157. Saravis CA, Kupchick HZ, O'Brien MJ, Zamcheck N . Zinc Glycinate Marker (ZGM). In Compendium of Assays for Immunodiagnosis of Human Cancer. Herberman R Ed. Elsevier-North Holland, Inc. 1979; 1:237-239.
  158. O'Brien MJ, Gottlieb LS . The Liver and Biliary Tract in: Pathologic Basis of Disease, Chapter 21. Robbins S, Cotran R, Eds. W.B. Saunders Co. Philadelphia,PA. 1979.
  159. Saravis CA, O'Brien M, Zamcheck N. Direct tissue isoelectric focusing in agarose. J Immunol Methods. 1979; 29(1):97-100. PMID: 385785.
    View in: PubMed
  160. Walsh MJ, O'Brien M, McCarthy CF. Chronic active liver disease: experiences with 17 patients. Ir J Med Sci. 1978 Jul; 147(7):223-9. PMID: 681148.
    View in: PubMed
Michael's Networks
Click the "See All" links for more information and interactive visualizations!
Concepts
_
BU Co-Authors
_
Similar BU People
_
Same Department