Keywords
Last Name

Muhammad Zaman, PhD

TitleProfessor
InstitutionBoston University College of Engineering
DepartmentBiomedical Engineering
Address44 Cummington St
Boston MA 02215
Phone(617) 353-2805
Other Positions
TitleAssociate Chair for Undergraduate Studies
InstitutionBoston University College of Engineering
DepartmentBiomedical Engineering

TitleAssistant Professor
InstitutionBoston University School of Public Health
DepartmentGlobal Health

TitleGraduate Faculty (Primary Mentor of Grad Students)
InstitutionBoston University School of Medicine, Division of Graduate Medical Sciences

 Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Weinstein ZB, Zaman MH. Quantitative bioassay to identify antimicrobial drugs through drug interaction fingerprint analysis. Sci Rep. 2017 Feb 16; 7:42644. PMID: 28205640.
    View in: PubMed
  2. Sun M, Zaman MH. Modeling, signaling and cytoskeleton dynamics: integrated modeling-experimental frameworks in cell migration. Wiley Interdiscip Rev Syst Biol Med. 2017 Jan; 9(1). PMID: 27863122.
    View in: PubMed
  3. Spill F, Weinstein ZB, Irani Shemirani A, Ho N, Desai D, Zaman MH. Controlling uncertainty in aptamer selection. Proc Natl Acad Sci U S A. 2016 Oct 25; 113(43):12076-12081. PMID: 27790993.
    View in: PubMed
  4. Vargas DA, Sun M, Sadykov K, Kukuruzinska MA, Zaman MH. The Integrated Role of Wnt/ß-Catenin, N-Glycosylation, and E-Cadherin-Mediated Adhesion in Network Dynamics. PLoS Comput Biol. 2016 Jul; 12(7):e1005007. PMID: 27427963.
    View in: PubMed
  5. Spill F, Andasari V, Mak M, Kamm RD, Zaman MH. Effects of 3D geometries on cellular gradient sensing and polarization. Phys Biol. 2016 06 25; 13(3):036008. PMID: 27345945.
    View in: PubMed
  6. Sun M, Spill F, Zaman MH. A Computational Model of YAP/TAZ Mechanosensing. Biophys J. 2016 Jun 07; 110(11):2540-50. PMID: 27276271.
    View in: PubMed
  7. Sun M, Bloom AB, Zaman MH. Correction: Rapid Quantification of 3D Collagen Fiber Alignment and Fiber Intersection Correlations with High Sensitivity. PLoS One. 2016; 11(6):e0157379. PMID: 27272026.
    View in: PubMed
  8. Spill F, Reynolds DS, Kamm RD, Zaman MH. Impact of the physical microenvironment on tumor progression and metastasis. Curr Opin Biotechnol. 2016 Aug; 40:41-8. PMID: 26938687.
    View in: PubMed
  9. Mak M, Spill F, Kamm RD, Zaman MH. Single-Cell Migration in Complex Microenvironments: Mechanics and Signaling Dynamics. J Biomech Eng. 2016 Feb; 138(2):021004. PMID: 26639083.
    View in: PubMed
  10. Clifford KL, Zaman MH. Engineering, global health, and inclusive innovation: focus on partnership, system strengthening, and local impact for SDGs. Glob Health Action. 2016; 9:30175. PMID: 26790462.
    View in: PubMed
  11. Mak M, Zaman MH, Kamm RD, Kim T. Interplay of active processes modulates tension and drives phase transition in self-renewing, motor-driven cytoskeletal networks. Nat Commun. 2016; 7:10323. PMID: 26744226.
    View in: PubMed
  12. Clifford KL, Zaman MH. Engineering, global health, and inclusive innovation: focus on partnership, system strengthening, and local impact for SDGs. Glob Health Action. 2016 Jan; 9(1):30175. PMID: 28156950.
    View in: PubMed
  13. Sharma Y, Vargas DA, Pegoraro AF, Lepzelter D, Weitz DA, Zaman MH. Collective motion of mammalian cell cohorts in 3D. Integr Biol (Camb). 2015 Dec; 7(12):1526-33. PMID: 26549557.
    View in: PubMed
  14. Sun M, Bloom AB, Zaman MH. Rapid Quantification of 3D Collagen Fiber Alignment and Fiber Intersection Correlations with High Sensitivity. PLoS One. 2015; 10(7):e0131814. PMID: 26158674.
    View in: PubMed
  15. Mak M, Kim T, Zaman MH, Kamm RD. Multiscale mechanobiology: computational models for integrating molecules to multicellular systems. Integr Biol (Camb). 2015 Oct; 7(10):1093-108. PMID: 26019013.
    View in: PubMed
  16. Bourouba M, Zergoun AA, Maffei JS, Chila D, Djennaoui D, Asselah F, Amir-Tidadini ZC, Touil-Boukoffa C, Zaman MH. TNFa antagonization alters NOS2 dependent nasopharyngeal carcinoma tumor growth. Cytokine. 2015 Jul; 74(1):157-63. PMID: 25912222.
    View in: PubMed
  17. Ho NT, Desai D, Zaman MH. Rapid and specific drug quality testing assay for artemisinin and its derivatives using a luminescent reaction and novel microfluidic technology. Am J Trop Med Hyg. 2015 Jun; 92(6 Suppl):24-30. PMID: 25897061.
    View in: PubMed
  18. Zaman MH. Maternal health in developing countries: engineering approaches and future outlook. IEEE Pulse. 2015 Jan-Feb; 6(1):25-7. PMID: 25616265.
    View in: PubMed
  19. Mak M, Kamm RD, Zaman MH. Impact of dimensionality and network disruption on microrheology of cancer cells in 3D environments. PLoS Comput Biol. 2014 Nov; 10(11):e1003959. PMID: 25412385.
    View in: PubMed
  20. Wu G, Zaman MH. Amperometric measurements of ethanol on paper with a glucometer. Talanta. 2015 Mar; 134:194-9. PMID: 25618657.
    View in: PubMed
  21. Maffei JS, Srivastava J, Fallica B, Zaman MH. Combinative in vitro studies and computational model to predict 3D cell migration response to drug insult. Integr Biol (Camb). 2014 Oct; 6(10):957-72. PMID: 25174457.
    View in: PubMed
  22. Garcia P, Armstrong R, Zaman MH. Models of education in medicine, public health, and engineering. Science. 2014 Sep 12; 345(6202):1281-3. PMID: 25214613.
    View in: PubMed
  23. Mak M, Zaman M, Kamm R. SU-E-J-41: Computational and Experimental Analysis of Cancer Cell Mechanics in 3D: Intracellular Viscoelasticity and Internal Stresses. Med Phys. 2014 Jun; 41(6):164. PMID: 28038239.
    View in: PubMed
  24. Lepzelter D, Zaman MH. Modeling persistence in mesenchymal cell motility using explicit fibers. Langmuir. 2014 May 20; 30(19):5506-9. PMID: 24800650.
    View in: PubMed
  25. Bloom AB, Zaman MH. Influence of the microenvironment on cell fate determination and migration. Physiol Genomics. 2014 May 1; 46(9):309-14. PMID: 24619520.
    View in: PubMed
  26. Forciniti L, Ybarra J, Zaman MH, Schmidt CE. Schwann cell response on polypyrrole substrates upon electrical stimulation. Acta Biomater. 2014 Jun; 10(6):2423-33. PMID: 24512979.
    View in: PubMed
  27. Wu G, Srivastava J, Zaman MH. Stability measurements of antibodies stored on paper. Anal Biochem. 2014 Mar 15; 449:147-54. PMID: 24361717.
    View in: PubMed
  28. Charoen KM, Fallica B, Colson YL, Zaman MH, Grinstaff MW. Embedded multicellular spheroids as a biomimetic 3D cancer model for evaluating drug and drug-device combinations. Biomaterials. 2014 Feb; 35(7):2264-71. PMID: 24360576.
    View in: PubMed
  29. Schwartz MP, Rogers RE, Singh SP, Lee JY, Loveland SG, Koepsel JT, Witze ES, Montanez-Sauri SI, Sung KE, Tokuda EY, Sharma Y, Everhart LM, Nguyen EH, Zaman MH, Beebe DJ, Ahn NG, Murphy WL, Anseth KS. A quantitative comparison of human HT-1080 fibrosarcoma cells and primary human dermal fibroblasts identifies a 3D migration mechanism with properties unique to the transformed phenotype. PLoS One. 2013; 8(12):e81689. PMID: 24349113.
    View in: PubMed
  30. Zaman MH. The role of engineering approaches in analysing cancer invasion and metastasis. Nat Rev Cancer. 2013 Aug; 13(8):596-603. PMID: 23864050.
    View in: PubMed
  31. Vargas DA, Bates O, Zaman MH. Computational model to probe cellular mechanics during epithelial-mesenchymal transition. Cells Tissues Organs. 2013; 197(6):435-44. PMID: 23774741.
    View in: PubMed
  32. Katira P, Bonnecaze RT, Zaman MH. Modeling the mechanics of cancer: effect of changes in cellular and extra-cellular mechanical properties. Front Oncol. 2013; 3:145. PMID: 23781492.
    View in: PubMed
  33. Chisholm RH, Hughes BD, Landman KA, Zaman MH. Analytic study of three-dimensional single cell migration with and without proteolytic enzymes. Cell Mol Bioeng. 2013 Jun 01; 6(2). PMID: 24348878.
    View in: PubMed
  34. Frascoli F, Hughes BD, Zaman MH, Landman KA. A computational model for collective cellular motion in three dimensions: general framework and case study for cell pair dynamics. PLoS One. 2013; 8(3):e59249. PMID: 23527148.
    View in: PubMed
  35. Harjanto D, Zaman MH. Modeling extracellular matrix reorganization in 3D environments. PLoS One. 2013; 8(1):e52509. PMID: 23341900.
    View in: PubMed
  36. Fong EJ, Sharma Y, Fallica B, Tierney DB, Fortune SM, Zaman MH. Decoupling directed and passive motion in dynamic systems: particle tracking microrheology of sputum. Ann Biomed Eng. 2013 Apr; 41(4):837-46. PMID: 23271563.
    View in: PubMed
  37. Sakamoto Y, Prudhomme S, Zaman MH. Modeling of adhesion, protrusion, and contraction coordination for cell migration simulations. J Math Biol. 2014 Jan; 68(1-2):267-302. PMID: 23263301.
    View in: PubMed
  38. Lepzelter D, Zaman M. Subdiffusion of proteins and oligomers on membranes. J Chem Phys. 2012 Nov 7; 137(17):175102. PMID: 23145748.
    View in: PubMed
  39. Fallica B, Maffei JS, Villa S, Makin G, Zaman M. Alteration of cellular behavior and response to PI3K pathway inhibition by culture in 3D collagen gels. PLoS One. 2012; 7(10):e48024. PMID: 23110163.
    View in: PubMed
  40. Wu G, Zaman MH. Low-cost tools for diagnosing and monitoring HIV infection in low-resource settings. Bull World Health Organ. 2012 Dec 1; 90(12):914-20. PMID: 23284197.
    View in: PubMed
  41. Fernandes A, Zaman MH. The role of biomedical engineering in disaster management in resource-limited settings. Bull World Health Organ. 2012 Aug 1; 90(8):631-2. PMID: 22893748.
    View in: PubMed
  42. Lepzelter D, Bates O, Zaman M. Integrin clustering in two and three dimensions. Langmuir. 2012 Mar 27; 28(12):5379-86. PMID: 22204631.
    View in: PubMed
  43. Katira P, Zaman MH, Bonnecaze RT. How changes in cell mechanical properties induce cancerous behavior. Phys Rev Lett. 2012 Jan 13; 108(2):028103. PMID: 22324713.
    View in: PubMed
  44. Harjanto D, Maffei JS, Zaman MH. Quantitative analysis of the effect of cancer invasiveness and collagen concentration on 3D matrix remodeling. PLoS One. 2011; 6(9):e24891. PMID: 21980363.
    View in: PubMed
  45. Sakamoto Y, Prudhomme S, Zaman MH. Viscoelastic gel-strip model for the simulation of migrating cells. Ann Biomed Eng. 2011 Nov; 39(11):2735-49. PMID: 21800204.
    View in: PubMed
  46. Tambe DT, Hardin CC, Angelini TE, Rajendran K, Park CY, Serra-Picamal X, Zhou EH, Zaman MH, Butler JP, Weitz DA, Fredberg JJ, Trepat X. Collective cell guidance by cooperative intercellular forces. Nat Mater. 2011 Jun; 10(6):469-75. PMID: 21602808.
    View in: PubMed
  47. Baker EL, Srivastava J, Yu D, Bonnecaze RT, Zaman MH. Cancer cell migration: integrated roles of matrix mechanics and transforming potential. PLoS One. 2011; 6(5):e20355. PMID: 21647371.
    View in: PubMed
  48. Vargas DA, Zaman MH. Computational model for migration of a cell cluster in three-dimensional matrices. Ann Biomed Eng. 2011 Jul; 39(7):2068-79. PMID: 21424851.
    View in: PubMed
  49. Fallica B, Makin G, Zaman MH. Bioengineering approaches to study multidrug resistance in tumor cells. Integr Biol (Camb). 2011 May; 3(5):529-39. PMID: 21387035.
    View in: PubMed
  50. Lepzelter D, Zaman MH. Clustered diffusion of integrins. Biophys J. 2010 Dec 15; 99(12):L106-8. PMID: 21156122.
    View in: PubMed
  51. Desai D, Wu G, Zaman MH. Tackling HIV through robust diagnostics in the developing world: current status and future opportunities. Lab Chip. 2011 Jan 21; 11(2):194-211. PMID: 21125097.
    View in: PubMed
  52. Baker EL, Lu J, Yu D, Bonnecaze RT, Zaman MH. Cancer cell stiffness: integrated roles of three-dimensional matrix stiffness and transforming potential. Biophys J. 2010 Oct 6; 99(7):2048-57. PMID: 20923638.
    View in: PubMed
  53. Wang G, Zaman MH. Communications: Hamiltonian regulated cell signaling network. J Chem Phys. 2010 Mar 28; 132(12):121103. PMID: 20370106.
    View in: PubMed
  54. Harjanto D, Zaman MH. Computational study of proteolysis-driven single cell migration in a three-dimensional matrix. Ann Biomed Eng. 2010 May; 38(5):1815-25. PMID: 20195760.
    View in: PubMed
  55. Schwartz MP, Fairbanks BD, Rogers RE, Rangarajan R, Zaman MH, Anseth KS. A synthetic strategy for mimicking the extracellular matrix provides new insight about tumor cell migration. Integr Biol (Camb). 2010 Jan; 2(1):32-40. PMID: 20473410.
    View in: PubMed
  56. Harjanto D, Zaman MH. Matrix mechanics and receptor-ligand interactions in cell adhesion. Org Biomol Chem. 2010 Jan 21; 8(2):299-304. PMID: 20066262.
    View in: PubMed
  57. Nair AB, Kim HD, Chakraborty B, Singh J, Zaman M, Gupta A, Friden PM, Murthy SN. Ungual and trans-ungual iontophoretic delivery of terbinafine for the treatment of onychomycosis. J Pharm Sci. 2009 Nov; 98(11):4130-40. PMID: 19340887.
    View in: PubMed
  58. Baker EL, Zaman MH. The biomechanical integrin. J Biomech. 2010 Jan 5; 43(1):38-44. PMID: 19811786.
    View in: PubMed
  59. Baker EL, Bonnecaze RT, Zaman MH. Extracellular matrix stiffness and architecture govern intracellular rheology in cancer. Biophys J. 2009 Aug 19; 97(4):1013-21. PMID: 19686648.
    View in: PubMed
  60. Kness M, Wang G, Zaman MH. Robustness of integrin signaling network. J Chem Phys. 2009 Jun 21; 130(23):235103. PMID: 19548764.
    View in: PubMed
  61. Forciniti L, Schmidt CE, Zaman MH. Computational model provides insight into the distinct responses of neurons to chemical and topographical cues. Ann Biomed Eng. 2009 Feb; 37(2):363-74. PMID: 19067167.
    View in: PubMed
  62. Yang T, Zaman MH. Cell adhesion to nanoligands: effects of ligand size and concentration in solution. Langmuir. 2008 Oct 21; 24(20):11819-27. PMID: 18816080.
    View in: PubMed
  63. Harley BA, Kim HD, Zaman MH, Yannas IV, Lauffenburger DA, Gibson LJ. Microarchitecture of three-dimensional scaffolds influences cell migration behavior via junction interactions. Biophys J. 2008 Oct; 95(8):4013-24. PMID: 18621811.
    View in: PubMed
  64. Enderling H, Alexander NR, Clark ES, Branch KM, Estrada L, Crooke C, Jourquin J, Lobdell N, Zaman MH, Guelcher SA, Anderson AR, Weaver AM. Dependence of invadopodia function on collagen fiber spacing and cross-linking: computational modeling and experimental evidence. Biophys J. 2008 Sep; 95(5):2203-18. PMID: 18515372.
    View in: PubMed
  65. Rangarajan R, Zaman MH. Modeling cell migration in 3D: Status and challenges. Cell Adh Migr. 2008 Apr-May; 2(2):106-9. PMID: 19262098.
    View in: PubMed
  66. Zaman MH. Cell adhesion & migration. Cell Adh Migr. 2008 Apr-May; 2(2):53-4. PMID: 19262104.
    View in: PubMed
  67. Zaman MH. Computer simulations in connective tissue research: successes and challenges. Connect Tissue Res. 2008; 49(3):162-4. PMID: 18661334.
    View in: PubMed
  68. Zaman MH. A multiscale probabilisitic framework to model early steps in tumor metastasis. Mol Cell Biomech. 2007 Sep; 4(3):133-41. PMID: 18320900.
    View in: PubMed
  69. Yang T, Zaman MH. Free energy landscape of receptor-mediated cell adhesion. J Chem Phys. 2007 Jan 28; 126(4):045103. PMID: 17286513.
    View in: PubMed
  70. Zaman MH. Understanding the molecular basis for differential binding of integrins to collagen and gelatin. Biophys J. 2007 Jan 15; 92(2):L17-9. PMID: 17098789.
    View in: PubMed
  71. Zaman MH, Matsudaira P, Lauffenburger DA. Understanding effects of matrix protease and matrix organization on directional persistence and translational speed in three-dimensional cell migration. Ann Biomed Eng. 2007 Jan; 35(1):91-100. PMID: 17080315.
    View in: PubMed
  72. Wolf-Yadlin A, Kumar N, Zhang Y, Hautaniemi S, Zaman M, Kim HD, Grantcharova V, Lauffenburger DA, White FM. Effects of HER2 overexpression on cell signaling networks governing proliferation and migration. Mol Syst Biol. 2006; 2:54. PMID: 17016520.
    View in: PubMed
  73. Zaman MH, Trapani LM, Sieminski AL, Siemeski A, Mackellar D, Gong H, Kamm RD, Wells A, Lauffenburger DA, Matsudaira P. Migration of tumor cells in 3D matrices is governed by matrix stiffness along with cell-matrix adhesion and proteolysis. Proc Natl Acad Sci U S A. 2006 Jul 18; 103(29):10889-94. PMID: 16832052.
    View in: PubMed
  74. Kumar N, Zaman MH, Kim HD, Lauffenburger DA. A high-throughput migration assay reveals HER2-mediated cell migration arising from increased directional persistence. Biophys J. 2006 Aug 15; 91(4):L32-4. PMID: 16782798.
    View in: PubMed
  75. Zaman MH. Misfolding dynamics of human prion protein. Mol Cell Biomech. 2005 Dec; 2(4):179-90. PMID: 16705864.
    View in: PubMed
  76. Jha AK, Colubri A, Zaman MH, Koide S, Sosnick TR, Freed KF. Helix, sheet, and polyproline II frequencies and strong nearest neighbor effects in a restricted coil library. Biochemistry. 2005 Jul 19; 44(28):9691-702. PMID: 16008354.
    View in: PubMed
  77. Zaman MH, Kamm RD, Matsudaira P, Lauffenburger DA. Computational model for cell migration in three-dimensional matrices. Biophys J. 2005 Aug; 89(2):1389-97. PMID: 15908579.
    View in: PubMed
  78. Zaman MH, Kaazempur-Mofrad MR. How flexible is alpha-actinin's rod domain? Mech Chem Biosyst. 2004 Dec; 1(4):291-302. PMID: 16783925.
    View in: PubMed
  79. Zaman MH, Shen MY, Berry RS, Freed KF, Sosnick TR. Investigations into sequence and conformational dependence of backbone entropy, inter-basin dynamics and the Flory isolated-pair hypothesis for peptides. J Mol Biol. 2003 Aug 15; 331(3):693-711. PMID: 12899838.
    View in: PubMed
  80. Zaman MH, Berry RS, Sosnick TR. Entropic benefit of a cross-link in protein association. Proteins. 2002 Aug 1; 48(2):341-51. PMID: 12112701.
    View in: PubMed
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