Catherine M. Klapperich, PhD
Professor
Boston University College of Engineering
Dept of Biomedical Engineering

PhD, University of California, Los Angeles
MS, Harvard University




Dr. Catherine Klapperich is the Associate Dean for Research and the Director of the NIBIB POCTRN Center for Future Technologies in Cancer Care (CFTCC) at BU.

She is a Kern Innovation Faculty Fellow and an Associate Professor of Biomedical Engineering at Boston University. She was named the Dorf-Ebner Distinguished Faculty Fellow in 2014. She also holds appointments in the Division of Materials Science and Engineering and the Department of Mechanical Engineering. She is the Director of the Laboratory for Diagnostics and Global Healthcare Technologies and a member of the Center for Nanoscience and Nanotechnology. In 2014, Dr. Klapperich was elected a Fellow of the American Institute for Medical and Biological Engineering. She is also a guest faculty member in the Global Health Delivery Project at Harvard University.

Before coming to Boston, Dr. Klapperich was a Postdoctoral Fellow at Lawrence Berkeley Laboratory in the lab of Dr. Carolyn Bertozzi, and was a Senior Research Scientist at Aclara Biosciences in Mountain View, CA. She earned her Ph.D. in Mechanical Engineering in 2000 from the University of California, Berkeley with Drs. Lisa Pruitt and Kyriakos Komvopoulos; her M.S. in Engineering Sciences from Harvard University and her B.S. in Materials Science and Engineering from Northwestern University.

Dr. Klapperich’s research is focused on engineering medical devices for use in low resource settings and at the point of care. Current projects are focused on disposable microfluidic diagnostics that incorporate on-board sample preparation and on minimally instrumented devices to enable molecular diagnostics. Her work includes diagnostics for infectious diarrhea, respiratory infections, HIV and other sexually transmitted diseases. These devices have been tested in Nicaragua and Kenya. Other work in the lab is focused on the design and deployment of devices to enable systems biology approaches to studying complex diseases including TB.

Dr. Klapperich’s lab is funded by grants from the NIH, DOD, CIMIT and the Coulter Foundation. In 2010, she was an invited participant in the National Academies of Engineering Frontiers of Engineering conference held in Agra, India. She serves on the editorial board of Biomedical Microdevices and is an active participant in both national and international research conferences.

Associate Dean for Research and Technology Development
Boston University College of Engineering


Professor
Boston University College of Engineering
Mechanical Engineering


Member
Boston University
BU-BMC Cancer Center


Member
Boston University
Evans Center for Interdisciplinary Biomedical Research




Novel Biosensors based on Mining Bacterial Transcription Factors
07/01/2020 - 03/31/2025 (Multi-PI)
PI: Catherine M. Klapperich, PhD
NIH/National Institute of Biomedical Imaging & Bioengineering
5R01EB029795-02

Flipped Biomedical Grand Rounds: Creating a Clinical Immersion Classroom
06/04/2018 - 03/31/2023 (Multi-PI)
PI: Catherine M. Klapperich, PhD
NIH/National Institute of Biomedical Imaging & Bioengineering
5R25EB025788-05

Rapid Molecular Diagnosts for Chlamydia and Gonorrhea at the Point-of-Care
04/01/2015 - 03/31/2021 (PI)
NIH/National Institute of Allergy & Infectious Diseases
5R01AI113927-04

Portable Nucleic Acid Prep, Storage, and Shipping Device
11/01/2017 - 04/30/2019 (PI)
Bill and Melinda Gates Foundation


Paper Microfluidic Chip for Isothermal Amplification and Lateral Flow Detection of Human Papillomaviru (HPVs)
05/01/2017 - 06/30/2018 (Subcontract PI)
The General Hospital Corporation d/b/a Massachusetts General Hospital NIH NIBIB
5U54EB015408-05

Center for Innovation in Point of Care Technologies for the Future of Cancer Care
07/01/2016 - 06/30/2018 (PI)
NIH/National Institute of Biomedical Imaging & Bioengineering
4U54EB015403-05

Rapid and multiplex diagnosis of maternal bacterial infections
11/15/2017 - 03/15/2018 (Subcontract PI)
Mount Kenya University AESA GrndChal Africa


Organic Biosensors for Personal Physiologic Monitoring
04/11/2016 - 10/10/2017 (Co-Investigator)
PI: James E. Galagan, PhD
Department of Defense/DARPA


Paper Microfluidic Chip for Isothermal Amplification and Lateral Flow Detection of HPV DNA
04/15/2015 - 06/30/2017 (Subcontract PI)
The General Hospital Corporation d/b/a Massachusetts General Hospital NIH NIBIB
4U54EB015408-05

Center for Innovation in Point of Care Technologies for the Future of Cancer Care
07/01/2012 - 06/30/2017 (PI)
NIH/National Institute of Biomedical Imaging & Bioengineering
5U54EB015403-04

Showing 10 of 20 results. Show All Results


Title


Yr Title Project-Sub Proj Pubs
2022 Novel Biosensors based on Mining Bacterial Transcription Factors 5R01EB029795-02
2022 Flipped Biomedical Grand Rounds: Creating a Clinical Immersion Classroom 5R25EB025788-05
2021 Flipped Biomedical Grand Rounds: Creating a Clinical Immersion Classroom 5R25EB025788-04
2020 Novel Biosensors based on Mining Bacterial Transcription Factors 1R01EB029795-01
2020 Flipped Biomedical Grand Rounds: Creating a Clinical Immersion Classroom 5R25EB025788-03
2018 Rapid molecular diagnostic for chlamydia and gonorrhea at the point-of-care 5R01AI113927-04 5
2017 2017 Microfluidics, Physics and Chemistry of Gordon Research Conference and Gordon Research Seminar 1R13EB024404-01A1
2017 Rapid molecular diagnostic for chlamydia and gonorrhea at the point-of-care 5R01AI113927-03 5
2016 Rapid Paper-based Diagnostics of CT / Trich 1R43AI122497-01
2016 Rapid molecular diagnostic for chlamydia and gonorrhea at the point-of-care 5R01AI113927-02 5
Showing 10 of 39 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Bouton TC, Atarere J, Turcinovic J, Seitz S, Sher-Jan C, Gilbert M, White L, Zhou Z, Hossain MM, Overbeck V, Doucette-Stamm L, Platt J, Landsberg HE, Hamer DH, Klapperich C, Jacobson KR, Connor JH. Viral dynamics of Omicron and Delta SARS-CoV-2 variants with implications for timing of release from isolation: a longitudinal cohort study. Clin Infect Dis. 2022 Jun 23.View Related Profiles. PMID: 35737948
     
  2. Landaverde L, McIntyre D, Robson J, Fu D, Ortiz L, Chen R, Oliveira SMD, Fan A, Barrett A, Burgay SP, Choate S, Corbett D, Doucette-Stamm L, Gonzales K, Hamer DH, Huang L, Huval S, Knight C, Landa C, Lindquist D, Lockard K, Macdowell TL, Mauro E, McGinty C, Miller C, Monahan M, Moore R, Platt J, Rolles L, Roy J, Schroeder T, Tolan DR, Zaia A, Brown RA, Waters G, Densmore D, Klapperich CM. Buildout and integration of an automated high-throughput CLIA laboratory for SARS-CoV-2 testing on a large urban campus. SLAS Technol. 2022 Jun 17.View Related Profiles. PMID: 35718332; PMCID: PMC9212990; DOI: 10.1016/j.slast.2022.06.003;
     
  3. Petros BA, Turcinovic J, Welch NL, White LF, Kolaczyk ED, Bauer MR, Cleary M, Dobbins ST, Doucette-Stamm L, Gore M, Nair P, Nguyen TG, Rose S, Taylor BP, Tsang D, Wendlandt E, Hope M, Platt JT, Jacobson KR, Bouton T, Yune S, Auclair JR, Landaverde L, Klapperich CM, Hamer DH, Hanage WP, MacInnis BL, Sabeti PC, Connor JH, Springer M. Early introduction and rise of the Omicron SARS-CoV-2 variant in highly vaccinated university populations. Clin Infect Dis. 2022 May 25.View Related Profiles. PMID: 35616119
     
  4. Sankar K, Baer R, Grazon C, Sabatelle RC, Lecommandoux S, Klapperich CM, Galagan JE, Grinstaff MW. An Allosteric Transcription Factor DNA-Binding Electrochemical Biosensor for Progesterone. ACS Sens. 2022 Apr 22; 7(4):1132-1137.View Related Profiles. PMID: 35412319
     
  5. Bouton TC, Atarere J, Turcinovic J, Seitz S, Sher-Jan C, Gilbert M, White L, Zhou Z, Hossain MM, Overbeck V, Doucette-Stamm L, Platt J, Landsberg HE, Hamer DH, Klapperich C, Jacobson KR, Connor JH. Viral dynamics of Omicron and Delta SARS-CoV-2 variants with implications for timing of release from isolation: a longitudinal cohort study. medRxiv. 2022 Apr 05.View Related Profiles. PMID: 35411341; PMCID: PMC8996632; DOI: 10.1101/2022.04.04.22273429;
     
  6. Kuhfeldt K, Turcinovic J, Sullivan M, Landaverde L, Doucette-Stamm L, Hamer DH, Platt J, Klapperich C, Landsberg HE, Connor JH. Minimal SARS-CoV-2 classroom transmission at a large urban university experiencing repeated into campus introduction. medRxiv. 2022 Mar 16.View Related Profiles. PMID: 35313596; PMCID: PMC8936094; DOI: 10.1101/2022.03.16.22271983;
     
  7. Rosenbohm JM, Klapperich CM, Cabodi M. Tunable Duplex Semiquantitative Detection of Nucleic Acids with a Visual Lateral Flow Immunoassay Readout. Anal Chem. 2022 03 08; 94(9):3956-3962.View Related Profiles. PMID: 35199994
     
  8. Zamani M, Dupaty J, Baer RC, Kuzmanovic U, Fan A, Grinstaff MW, Galagan JE, Klapperich CM. Paper-Based Progesterone Sensor Using an Allosteric Transcription Factor. ACS Omega. 2022 Feb 22; 7(7):5804-5808.View Related Profiles. PMID: 35224340; PMCID: PMC8867790; DOI: 10.1021/acsomega.1c05737;
     
  9. Zamani M, Yang V, Maziashvili L, Fan G, Klapperich CM, Furst AL. Surface Requirements for Optimal Biosensing with Disposable Gold Electrodes. ACS Meas Sci Au. 2022 Apr 20; 2(2):91-95. PMID: 35479101; PMCID: PMC9026247; DOI: 10.1021/acsmeasuresciau.1c00042;
     
  10. Zamani M, Furst AL, Klapperich CM. Strategies for Engineering Affordable Technologies for Point-of-Care Diagnostics of Infectious Diseases. Acc Chem Res. 2021 10 19; 54(20):3772-3779. PMID: 34612619; PMCID: PMC8996141; DOI: 10.1021/acs.accounts.1c00434;
     
Showing 10 of 88 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 88 publications over 21 distinct years, with a maximum of 8 publications in 2009 and 2022

YearPublications
19991
20001
20012
20041
20062
20074
20084
20098
20106
20113
20127
20136
20143
20157
20165
20173
20182
20192
20207
20216
20228
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44 Cummington St
Boston MA 02215
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