Catherine M. Klapperich, PhD
Professor
Boston University College of Engineering
Biomedical Engineering

PhD, University of California, Berkeley
MS, Harvard University
BS, Northwestern University



Dr. Catherine Klapperich is the Associate Dean for Research and the Director of the NIBIB POCTRN Center for Future Technologies in Cancer Care (CFTCC) at BU.

She is a Kern Innovation Faculty Fellow and an Associate Professor of Biomedical Engineering at Boston University. She was named the Dorf-Ebner Distinguished Faculty Fellow in 2014. She also holds appointments in the Division of Materials Science and Engineering and the Department of Mechanical Engineering. She is the Director of the Laboratory for Diagnostics and Global Healthcare Technologies and a member of the Center for Nanoscience and Nanotechnology. In 2014, Dr. Klapperich was elected a Fellow of the American Institute for Medical and Biological Engineering. She is also a guest faculty member in the Global Health Delivery Project at Harvard University.

Before coming to Boston, Dr. Klapperich was a Postdoctoral Fellow at Lawrence Berkeley Laboratory in the lab of Dr. Carolyn Bertozzi, and was a Senior Research Scientist at Aclara Biosciences in Mountain View, CA. She earned her Ph.D. in Mechanical Engineering in 2000 from the University of California, Berkeley with Drs. Lisa Pruitt and Kyriakos Komvopoulos; her M.S. in Engineering Sciences from Harvard University and her B.S. in Materials Science and Engineering from Northwestern University.

Dr. Klapperich’s research is focused on engineering medical devices for use in low resource settings and at the point of care. Current projects are focused on disposable microfluidic diagnostics that incorporate on-board sample preparation and on minimally instrumented devices to enable molecular diagnostics. Her work includes diagnostics for infectious diarrhea, respiratory infections, HIV and other sexually transmitted diseases. These devices have been tested in Nicaragua and Kenya. Other work in the lab is focused on the design and deployment of devices to enable systems biology approaches to studying complex diseases including TB.

Dr. Klapperich’s lab is funded by grants from the NIH, DOD, CIMIT and the Coulter Foundation. In 2010, she was an invited participant in the National Academies of Engineering Frontiers of Engineering conference held in Agra, India. She serves on the editorial board of Biomedical Microdevices and is an active participant in both national and international research conferences.

Associate Dean for Research and Technology Development
Boston University College of Engineering


Professor
Boston University College of Engineering
Mechanical Engineering


Member
Boston University
BU-BMC Cancer Center


Member
Boston University
Evans Center for Interdisciplinary Biomedical Research




Equipment: MRI: Track 1 Acquisition of an Illumina NextSeq 2000 Sequencing Instrument
09/01/2023 - 08/31/2026 (Multi-PI)
PI: Catherine M. Klapperich, PhD
National Science Foundation
CBET-2320685

Clinical Evaluation of a Novel Digital Health Intervention for Nutritional Anemias
07/01/2023 - 06/30/2026 (PI)
Massachusetts Life Sciences Center


Novel Biosensors based on Mining Bacterial Transcription Factors
07/01/2020 - 03/31/2025 (Multi-PI)
PI: Catherine M. Klapperich, PhD
NIH/National Institute of Biomedical Imaging & Bioengineering
5R01EB029795-04

Flipped Biomedical Grand Rounds: Creating a Clinical Immersion Classroom
06/04/2018 - 03/31/2024 (Multi-PI)
PI: Catherine M. Klapperich, PhD
NIH/National Institute of Biomedical Imaging & Bioengineering
5R25EB025788-05

SARS-CoV-2 Variant Dynamics
10/01/2021 - 03/31/2023 (Subcontract PI)
Boston Medical Center Corporation China Evergrande Gr


Rapid Molecular Diagnosts for Chlamydia and Gonorrhea at the Point-of-Care
04/01/2015 - 03/31/2021 (PI)
NIH/National Institute of Allergy & Infectious Diseases
5R01AI113927-04

Portable Nucleic Acid Prep, Storage, and Shipping Device
11/01/2017 - 04/30/2019 (PI)
Bill and Melinda Gates Foundation


Paper Microfluidic Chip for Isothermal Amplification and Lateral Flow Detection of Human Papillomaviru (HPVs)
05/01/2017 - 06/30/2018 (Subcontract PI)
The General Hospital Corporation d/b/a Massachusetts General Hospital NIH NIBIB
5U54EB015408-05

Center for Innovation in Point of Care Technologies for the Future of Cancer Care
07/01/2016 - 06/30/2018 (PI)
NIH/National Institute of Biomedical Imaging & Bioengineering
4U54EB015403-05

Rapid and multiplex diagnosis of maternal bacterial infections
11/15/2017 - 03/15/2018 (Subcontract PI)
Mount Kenya University AESA GrndChal Africa


Showing 10 of 23 results. Show All Results


Title


Yr Title Project-Sub Proj Pubs
2024 Novel Biosensors based on Mining Bacterial Transcription Factors 5R01EB029795-04
2023 Novel Biosensors based on Mining Bacterial Transcription Factors 5R01EB029795-03
2022 Novel Biosensors based on Mining Bacterial Transcription Factors 5R01EB029795-02
2022 Flipped Biomedical Grand Rounds: Creating a Clinical Immersion Classroom 5R25EB025788-05
2021 Flipped Biomedical Grand Rounds: Creating a Clinical Immersion Classroom 5R25EB025788-04
2020 Novel Biosensors based on Mining Bacterial Transcription Factors 1R01EB029795-01
2020 Flipped Biomedical Grand Rounds: Creating a Clinical Immersion Classroom 5R25EB025788-03
2018 Rapid molecular diagnostic for chlamydia and gonorrhea at the point-of-care 5R01AI113927-04 5
2017 2017 Microfluidics, Physics and Chemistry of Gordon Research Conference and Gordon Research Seminar 1R13EB024404-01A1
2017 Rapid molecular diagnostic for chlamydia and gonorrhea at the point-of-care 5R01AI113927-03 5
Showing 10 of 41 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Shiluli C, Kamath S, Kanoi BN, Kimani R, Maina M, Waweru H, Kamita M, Ndirangu I, Abkallo HM, Oduor B, Pamme N, Dupaty J, Klapperich CM, Lolabattu SR, Gitaka J. Improving gonorrhoea molecular diagnostics: Genome mining-based identification of identical multi-repeat sequences (IMRS) in Neisseria gonorrhoeae. Heliyon. 2024 Mar 30; 10(6):e27344. PMID: 38533083; DOI: 10.1016/j.heliyon.2024.e27344;
     
  2. Turcinovic J, Kuhfeldt K, Sullivan M, Landaverde L, Platt JT, Alekseyev YO, Doucette-Stamm L, Hamer DH, Klapperich C, Landsberg HE, Connor JH. Transmission Dynamics and Rare Clustered Transmission Within an Urban University Population Before Widespread Vaccination. J Infect Dis. 2024 Feb 14; 229(2):485-492.View Related Profiles. PMID: 37856283
     
  3. Zamani M, Klapperich CM, Furst AL. Recent advances in gold electrode fabrication for low-resource setting biosensing. Lab Chip. 2023 Mar 01; 23(5):1410-1419. PMID: 36602146; DOI: 10.1039/d2lc00552b;
     
  4. Bouton TC, Atarere J, Turcinovic J, Seitz S, Sher-Jan C, Gilbert M, White L, Zhou Z, Hossain MM, Overbeck V, Doucette-Stamm L, Platt J, Landsberg HE, Hamer DH, Klapperich C, Jacobson KR, Connor JH. Viral Dynamics of Omicron and Delta Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Variants With Implications for Timing of Release from Isolation: A Longitudinal Cohort Study. Clin Infect Dis. 2023 Feb 08; 76(3):e227-e233.View Related Profiles. PMID: 35737948; DOI: 10.1093/cid/ciac510;
     
  5. Petros BA, Turcinovic J, Welch NL, White LF, Kolaczyk ED, Bauer MR, Cleary M, Dobbins ST, Doucette-Stamm L, Gore M, Nair P, Nguyen TG, Rose S, Taylor BP, Tsang D, Wendlandt E, Hope M, Platt JT, Jacobson KR, Bouton T, Yune S, Auclair JR, Landaverde L, Klapperich CM, Hamer DH, Hanage WP, MacInnis BL, Sabeti PC, Connor JH, Springer M. Early Introduction and Rise of the Omicron Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Variant in Highly Vaccinated University Populations. Clin Infect Dis. 2023 Feb 08; 76(3):e400-e408.View Related Profiles. PMID: 35616119; DOI: 10.1093/cid/ciac413;
     
  6. Landaverde L, Turcinovic J, Doucette-Stamm L, Gonzales K, Platt J, Connor JH, Klapperich C. Comparison of BinaxNOW and SARS-CoV-2 qRT-PCR Detection of the Omicron Variant from Matched Anterior Nares Swabs. Microbiol Spectr. 2022 Dec 21; 10(6):e0130722.View Related Profiles. PMID: 36255297; DOI: 10.1128/spectrum.01307-22;
     
  7. Turcinovic J, Kuhfeldt K, Sullivan M, Landaverde L, Platt JT, Doucette-Stamm L, Hanage WP, Hamer DH, Klapperich C, Landsberg HE, Connor JH. Linking contact tracing with genomic surveillance to deconvolute SARS-CoV-2 transmission on a university campus. iScience. 2022 Nov 18; 25(11):105337.View Related Profiles. PMID: 36246573; DOI: 10.1016/j.isci.2022.105337;
     
  8. Kuhfeldt K, Turcinovic J, Sullivan M, Landaverde L, Doucette-Stamm L, Hamer DH, Platt JT, Klapperich C, Landsberg HE, Connor JH. Examination of SARS-CoV-2 In-Class Transmission at a Large Urban University With Public Health Mandates Using Epidemiological and Genomic Methodology. JAMA Netw Open. 2022 Aug 01; 5(8):e2225430.View Related Profiles. PMID: 35930286; DOI: 10.1001/jamanetworkopen.2022.25430;
     
  9. Hall SM, Landaverde L, Gill CJ, Yee GM, Sullivan M, Doucette-Stamm L, Landsberg H, Platt JT, White L, Hamer DH, Klapperich CM. Comparison of anterior nares CT values in asymptomatic and symptomatic individuals diagnosed with SARS-CoV-2 in a university screening program. PLoS One. 2022; 17(7):e0270694.View Related Profiles. PMID: 35830378; DOI: 10.1371/journal.pone.0270694;
     
  10. Landaverde L, McIntyre D, Robson J, Fu D, Ortiz L, Chen R, Oliveira SMD, Fan A, Barrett A, Burgay SP, Choate S, Corbett D, Doucette-Stamm L, Gonzales K, Hamer DH, Huang L, Huval S, Knight C, Landa C, Lindquist D, Lockard K, Macdowell TL, Mauro E, McGinty C, Miller C, Monahan M, Moore R, Platt J, Rolles L, Roy J, Schroeder T, Tolan DR, Zaia A, Brown RA, Waters G, Densmore D, Klapperich CM. Buildout and integration of an automated high-throughput CLIA laboratory for SARS-CoV-2 testing on a large urban campus. SLAS Technol. 2022 Oct; 27(5):302-311.View Related Profiles. PMID: 35718332; DOI: 10.1016/j.slast.2022.06.003;
     
Showing 10 of 96 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 96 publications over 23 distinct years, with a maximum of 11 publications in 2022

YearPublications
19991
20001
20012
20041
20062
20074
20084
20098
20106
20113
20127
20136
20143
20157
20165
20173
20182
20192
20207
20216
202211
20233
20242
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44 Cummington St
Boston MA 02215
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