John H. Connor, PhD
Associate Professor
Boston University School of Medicine
Dept of Microbiology

PhD, Duke University



My laboratory studies the virus-host interaction. We take a variety of approaches from genetic to systems biology to biochemistry and molecular biology. We are studying how viruses take over the cellular protein synthesis apparatus, how cells effectively fight virus infection, and how the host responds to infection with viruses that cause hemorrhagic fever.

Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Division of Graduate Medical Sciences


Member
Boston University
Bioinformatics Graduate Program




Assessment of infection route and vulnerability of neural precursor classes to Zika virus
09/30/2016 - 08/31/2018 (Co-PI)
PI: Tarik Haydar, PhD
NIH/National Institute of Neurological D
1R21NS101151-01

Development of Near Real-Time, Multiplexed Diagnostics for Viral Hemorrhagic Fever
08/01/2011 - 07/31/2018 (PI)
NIH/National Institute of Allergy & Infe
5R01AI096159-05

Inclusivity and Exclusivity Testing of advanced assays for fever of unknown origin
04/13/2017 - 04/12/2018 (PI)
Becton, Dickinson and Company DOD Naval Res Lab


Elimination of pathogenic IgE in cystic fribrosis
08/01/2016 - 03/01/2018 (PI)
The Brigham and Women's Hospital, Inc. NIH NHLBI
4U54HL119145-04

role for polyamines in Ebola Virus Replication
02/01/2016 - 01/31/2018 (PI)
NIH/National Institute of Allergy & Infe
5R21AI121933-02

Point-of-Care Nanotechnology Diagnostic for Differential Fever Diagnosis
10/01/2015 - 10/31/2017 (PI)
Becton, Dickinson and Company Paul G. Allen Fdn


Biomarker Discovery
03/10/2015 - 02/28/2017 (PI)
Johns Hopkins University Applied Physics Ntl Intel - IARPA


I/UCRC Collaborative Research
07/01/2011 - 02/28/2017 (SP Co-PI of Sub-Project / SP)
I/UCRC: Industry Memberships


Evaluation of the mechanism of action of FDA-approved compounds that show activity against ebolavirus
08/18/2014 - 02/17/2017 (PI)
Department of Defense/Army Medical Resea


Elimination of pathogenic IgE in cystic fribrosis
02/01/2016 - 10/31/2016 (PI)
The Brigham and Women's Hospital, Inc. NIH NHLBI
4U54HL119145-04

Showing 10 of 16 results. Show All Results



Yr Title Project-Sub Proj Pubs
2017 Assessment of infection route and vulnerability of neural precursor classes to Zika virus 5R21NS101151-02
2017 Role for polyamines in Ebola Virus Replication 5R21AI121933-02 1
2016 Assessment of infection route and vulnerability of neural precursor classes to Zika virus 1R21NS101151-01
2016 Role for polyamines in Ebola Virus Replication 1R21AI121933-01 1
2015 Development of Near Real-Time, Multiplexed Diagnostics for Viral Hemorrhagic Feve 5R01AI096159-05 9
2014 Development of Near Real-Time, Multiplexed Diagnostics for Viral Hemorrhagic Feve 5R01AI096159-04 9
2013 Development of Near Real-Time, Multiplexed Diagnostics for Viral Hemorrhagic Feve 5R01AI096159-03 9
2012 Development of Near Real-Time, Multiplexed Diagnostics for Viral Hemorrhagic Feve 5R01AI096159-02 9
2012 Stage-Specific Inhibitors of Orthopoxviruses 5R03MH094169-02 2
2011 Development of Near Real-Time, Multiplexed Diagnostics for Viral Hemorrhagic Feve 1R01AI096159-01 9
Showing 10 of 17 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Speranza E, Altamura LA, Kulcsar K, Bixler SL, Rossi CA, Schoepp RJ, Nagle E, Aguilar W, Douglas CE, Delp KL, Minogue TD, Palacios G, Goff AJ, Connor JH. Comparison of Transcriptomic Platforms for Analysis of Whole Blood from Ebola-Infected Cynomolgus Macaques. Sci Rep. 2017 Nov 07; 7(1):14756. PMID: 29116224.
  2. Lo J, Zhang D, Speranza E, Negron JA, Connor JH. HoTResDB: Host Transcriptional Response Database for Viral Hemorrhagic Fevers. Bioinformatics. 2017 Sep 22. PMID: 29028885.
  3. Speranza E, Connor JH. Host Transcriptional Response to Ebola Virus Infection. Vaccines (Basel). 2017 Sep 20; 5(3). PMID: 28930167.
  4. Mounce BC, Olsen ME, Vignuzzi M, Connor JH. Polyamines and Their Role in Virus Infection. Microbiol Mol Biol Rev. 2017 Dec; 81(4). PMID: 28904024.
  5. Nelson EV, Pacheco JR, Hume AJ, Cressey TN, Deflubé LR, Ruedas JB, Connor JH, Ebihara H, Mühlberger E. An RNA polymerase II-driven Ebola virus minigenome system as an advanced tool for antiviral drug screening. Antiviral Res. 2017 Oct; 146:21-27.View Related Profiles. PMID: 28807685.
  6. Ruedas JB, Ladner JT, Ettinger CR, Gummuluru S, Palacios G, Connor JH. Spontaneous Mutation at Amino Acid 544 of the Ebola Virus Glycoprotein Potentiates Virus Entry and Selection in Tissue Culture. J Virol. 2017 Aug 01; 91(15).View Related Profiles. PMID: 28539437.
  7. Connor J, Kobinger G, Olinger G. Therapeutics Against Filovirus Infection. Curr Top Microbiol Immunol. 2017 Jun 27.View Related Profiles. PMID: 28653190.
  8. Schultz MJ, Isern S, Michael SF, Corley RB, Connor JH, Frydman HM. Variable Inhibition of Zika Virus Replication by Different Wolbachia Strains in Mosquito Cell Cultures. J Virol. 2017 Jul 15; 91(14).View Related Profiles. PMID: 28446677.
  9. Daaboul GG, Freedman DS, Scherr SM, Carter E, Rosca A, Bernstein D, Mire CE, Agans KN, Hoenen T, Geisbert TW, Ünlü MS, Connor JH. Enhanced light microscopy visualization of virus particles from Zika virus to filamentous ebolaviruses. PLoS One. 2017; 12(6):e0179728. PMID: 28651016.
  10. Rossignol ED, Peters KN, Connor JH, Bullitt E. Zika virus induced cellular remodelling. Cell Microbiol. 2017 Aug; 19(8).View Related Profiles. PMID: 28318141; DOI: 10.1111/cmi.12740;.
Showing 10 of 87 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 87 publications over 22 distinct years, with a maximum of 16 publications in 2017

YearPublications
19961
19971
19983
19992
20004
20013
20022
20031
20042
20051
20064
20072
20083
20092
20105
20116
20126
20134
20148
20155
20166
201716

Available to Mentor as: (Review Mentor Role Definitions):
  • Advisor
  • Co-Mentor or Peer Mentor
Contact for Mentoring:


72 E. Concord St Housman (R)
Boston MA 02118
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