John H. Connor, PhD
Associate Professor
Boston University School of Medicine
Dept of Microbiology

PhD, Duke University



My laboratory studies the virus-host interaction. We take a variety of approaches from genetic to systems biology to biochemistry and molecular biology. We are studying how viruses take over the cellular protein synthesis apparatus, how cells effectively fight virus infection, and how the host responds to infection with viruses that cause hemorrhagic fever.

Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Division of Graduate Medical Sciences


Member
Boston University
Department of Bioinformatics Graduate Program




Inclusivity and Exclusivity Testing of advanced assays for fever of unknown origin
04/13/2017 - 04/12/2018 (PI)
Becton, Dickinson and Company DOD Naval Res Lab

role for polyamines in Ebola Virus Replication
02/01/2016 - 01/31/2018 (PI)
NIH/National Institute of Allergy & Infectious Diseases
5R21AI121933-02

Point-of-Care Nanotechnology Diagnostic for Differential Fever Diagnosis
10/01/2015 - 10/31/2017 (PI)
Becton, Dickinson and Company Paul G. Allen Fdn

Assessment of infection route and vulnerability of neural precursor classes to Zika virus
09/30/2016 - 08/31/2017 (Co-PI)
PI: Tarik Haydar, PhD
NIH/National Institute of Neurological Disorders & Stroke
1R21NS101151-01

Elimination of pathogenic IgE in cystic fribrosis
08/01/2016 - 07/31/2017 (PI)
The Brigham and Women's Hospital, Inc. NIH NHLBI
4U54HL119145-04

Development of Near Real-Time, Multiplexed Diagnostics for Viral Hemorrhagic Fever
08/01/2011 - 07/31/2017 (PI)
NIH/National Institute of Allergy & Infectious Diseases
5R01AI096159-05

Biomarker Discovery
03/10/2015 - 02/28/2017 (PI)
Johns Hopkins University Applied Physics Laboratory LLC, The Ntl Intel - IARPA

I/UCRC Collaborative Research
07/01/2011 - 02/28/2017 (SP Co-PI of Sub-Project / SP)
I/UCRC: Industry Memberships

Evaluation of the mechanism of action of FDA-approved compounds that show activity against ebolavirus
08/18/2014 - 02/17/2017 (PI)
Department of Defense/Army Medical Research Acquisition Activity

Elimination of pathogenic IgE in cystic fribrosis
02/01/2016 - 10/31/2016 (PI)
The Brigham and Women's Hospital, Inc. NIH NHLBI
4U54HL119145-04

Showing 10 of 16 results. Show All Results



Yr Title Project-Sub Proj Pubs
2017 Role for polyamines in Ebola Virus Replication 5R21AI121933-02 1
2016 Assessment of infection route and vulnerability of neural precursor classes to Zika virus 1R21NS101151-01
2016 Role for polyamines in Ebola Virus Replication 1R21AI121933-01 1
2015 Development of Near Real-Time, Multiplexed Diagnostics for Viral Hemorrhagic Feve 5R01AI096159-05 9
2014 Development of Near Real-Time, Multiplexed Diagnostics for Viral Hemorrhagic Feve 5R01AI096159-04 9
2013 Development of Near Real-Time, Multiplexed Diagnostics for Viral Hemorrhagic Feve 5R01AI096159-03 9
2012 Development of Near Real-Time, Multiplexed Diagnostics for Viral Hemorrhagic Feve 5R01AI096159-02 9
2012 Stage-Specific Inhibitors of Orthopoxviruses 5R03MH094169-02 2
2011 Development of Near Real-Time, Multiplexed Diagnostics for Viral Hemorrhagic Feve 1R01AI096159-01 9
2011 Stage-Specific Inhibitors of Orthopoxviruses 1R03MH094169-01 2
Showing 10 of 16 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Rossignol ED, Peters KN, Connor JH, Bullitt E. Zika virus induced cellular remodelling. Cell Microbiol. 2017 Mar 20.View Related Profiles. PMID: 28318141; DOI: 10.1111/cmi.12740;.
  2. Scherr SM, Freedman DS, Agans KN, Rosca A, Carter E, Kuroda M, Fawcett HE, Mire CE, Geisbert TW, Ünlü MS, Connor JH. Disposable cartridge platform for rapid detection of viral hemorrhagic fever viruses. Lab Chip. 2017 Feb 28; 17(5):917-925. PMID: 28194457; DOI: 10.1039/c6lc01528j;.
  3. Liu X, Speranza E, Muñoz-Fontela C, Haldenby S, Rickett NY, Garcia-Dorival I, Fang Y, Hall Y, Zekeng EG, Lüdtke A, Xia D, Kerber R, Krumkamp R, Duraffour S, Sissoko D, Kenny J, Rockliffe N, Williamson ED, Laws TR, N''Faly M, Matthews DA, Günther S, Cossins AR, Sprecher A, Connor JH, Carroll MW, Hiscox JA. Transcriptomic signatures differentiate survival from fatal outcomes in humans infected with Ebola virus. Genome Biol. 2017 Jan 19; 18(1):4. PMID: 28100256; DOI: 10.1186/s13059-016-1137-3;.
  4. Olsen ME, Connor JH. Hypusination of eIF5A as a Target for Antiviral Therapy. DNA Cell Biol. 2017 Mar; 36(3):198-201. PMID: 28080131; DOI: 10.1089/dna.2016.3611;.
  5. Ünlü NL, Kanik FE, Seymour E, Connor JH, Ünlü MS. DNA-Directed Antibody Immobilization for Robust Protein Microarrays: Application to Single Particle Detection ''DNA-Directed Antibody Immobilization. Methods Mol Biol. 2017; 1571:187-206. PMID: 28281257; DOI: 10.1007/978-1-4939-6848-0_12;.
  6. Ruedas JB, Connor JH. Generating Recombinant Vesicular Stomatitis Viruses for Use as Vaccine Platforms. Methods Mol Biol. 2017; 1581:203-222. PMID: 28374251; DOI: 10.1007/978-1-4939-6869-5_12;.
  7. Caballero IS, Honko AN, Gire SK, Winnicki SM, Melé M, Gerhardinger C, Lin AE, Rinn JL, Sabeti PC, Hensley LE, Connor JH. In vivo Ebola virus infection leads to a strong innate response in circulating immune cells. BMC Genomics. 2016 Sep 05; 17:707. PMID: 27595844; PMCID: PMC5011782; DOI: 10.1186/s12864-016-3060-0;.
  8. Olsen ME, Filone CM, Rozelle D, Mire CE, Agans KN, Hensley L, Connor JH. Polyamines and Hypusination Are Required for Ebolavirus Gene Expression and Replication. MBio. 2016 Jul 26; 7(4).View Related Profiles. PMID: 27460797; PMCID: PMC4981715; DOI: 10.1128/mBio.00882-16;.
  9. Wilson MR, Fedewa G, Stenglein MD, Olejnik J, Rennick LJ, Nambulli S, Feldmann F, Duprex WP, Connor JH, Mühlberger E, DeRisi JL. Multiplexed Metagenomic Deep Sequencing To Analyze the Composition of High-Priority Pathogen Reagents. mSystems. 2016 Jul-Aug; 1(4).View Related Profiles. PMID: 27822544.
  10. Fawcett H, Ünlü MS, Connor JH. New Approaches for Virus Detection through Multidisciplinary Partnerships. ACS Infect Dis. 2016 Jun 10; 2(6):378-81. PMID: 27627625; DOI: 10.1021/acsinfecdis.6b00063;.
Showing 10 of 76 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 76 publications over 22 distinct years, with a maximum of 8 publications in 2014

YearPublications
19961
19971
19983
19992
20004
20013
20022
20031
20042
20051
20064
20072
20083
20092
20105
20116
20126
20134
20148
20155
20165
20176

Available to Mentor as: (Review Mentor Role Definitions):
  • Advisor
  • Co-Mentor or Peer Mentor
Contact for Mentoring:


72 E. Concord St Housman (R)
Boston MA 02118
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