John H. Connor, PhD
Professor
Boston University Chobanian & Avedisian School of Medicine
Virology, Immunology & Microbiology

PhD, Duke University
BA, Swarthmore College



My laboratory studies the virus-host interaction. We take a variety of approaches from genetic to systems biology to biochemistry and molecular biology. We are studying how viruses take over the cellular protein synthesis apparatus, how cells effectively fight virus infection, and how the host responds to infection with viruses that cause hemorrhagic fever.

Faculty
Boston University
National Emerging Infectious Disease Lab


Member
Boston University
Genome Science Institute


Member
Boston University
Bioinformatics Graduate Program


Graduate Faculty (Primary Mentor of Grad Students)
Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences




RFQ #7080-008 Bioinformatics
01/01/2024 - 08/31/2028 (Subcontract PI)
Mapp Biopharmaceutical, Inc. HHS ASPR BARDA


RESTRICTED: RFQ #7080-008 Bioinformatics
01/01/2024 - 08/31/2028 (Subcontract PI)
Mapp Biopharmaceutical, Inc. HHS ASPR BARDA


RFP 7079-024 Bioinformatics SUB-2023-7079-0010
08/22/2024 - 06/30/2027 (Subcontract PI)
Mapp Biopharmaceutical, Inc. HHS ASPR


RFP 7079-024 Bioinformatics
08/22/2024 - 06/30/2027 (Subcontract PI)
Mapp Biopharmaceutical, Inc. HHS ASPR


Screening Countermeasures In vitro for Filovirus Infections (SCIFI)
11/18/2024 - 11/18/2026 (Subcontract PI)
Draper Laboratory, Inc. HHS ASPR BARDA


Development of a rVSV Vectored Vaccine for Lassa Virus: Nonhuman Primate Efficacy and Immunogenicity Studies
09/01/2021 - 08/31/2026 (Subcontract PI)
University of Texas Medical Branch at Galveston DOD DTRA


Determinants of COVID19-induced venous thrombosis and targeted therapy assessed with bioengineered vein-chip
05/01/2021 - 04/30/2026 (PI)
NIH/National Heart, Lung, and Blood Institute
5R01HL157790-04

Advancement of a poxvirus inhibitor
03/12/2020 - 02/28/2026 (PI)
NIH/National Institute of Allergy & Infectious Diseases
5R01AI151559-05

Modular point-of-care platform for differential diagnosis of viral hemorrhagic fevers
10/01/2023 - 09/30/2025 (Subcontract PI)
RedBud Labs NIH NIAID
4R44AI150263-03

New England Pathogen Genomics Center of Excellence
07/01/2023 - 09/30/2025 (Subcontract PI)
Comm. of Mass./Department of Public Health HHS CDC


Showing 10 of 38 results. Show All Results


Title


Yr Title Project-Sub Proj Pubs
2025 Advancement of a poxvirus antiviral 2R01AI151559-06
2024 Determinants of COVID19-induced venous thrombosis and targeted therapy assessed with bioengineered vein-chip 5R01HL157790-04
2024 Advancement of poxvirus inhibitor 5R01AI151559-05
2023 Determinants of COVID19-induced venous thrombosis and targeted therapy assessed with bioengineered vein-chip 5R01HL157790-03
2023 Advancement of poxvirus inhibitor 5R01AI151559-04
2022 Determinants of COVID19-induced venous thrombosis and targeted therapy assessed with bioengineered vein-chip 5R01HL157790-02
2022 Advancement of poxvirus inhibitor 5R01AI151559-03
2021 Determinants of COVID19-induced venous thrombosis and targeted therapy assessed with bioengineered vein-chip 1R01HL157790-01
2021 Advancement of poxvirus inhibitor 5R01AI151559-02
2020 Advancement of poxvirus inhibitor 1R01AI151559-01
Showing 10 of 29 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Website       Copy PMIDs To Clipboard

  1. Kenney D, O'Connell AK, Tseng AE, Turcinovic J, Sheehan ML, Nitido AD, Montanaro P, Gertje HP, Ericsson M, Connor JH, Vrbanac V, Crossland NA, Harly C, Balazs AB, Douam F. Immune signatures of SARS-CoV-2 infection resolution in human lung tissues. PLoS Pathog. 2025 Sep; 21(9):e1013469.View Related Profiles. PMID: 40920821; PMCID: PMC12425302; DOI: 10.1371/journal.ppat.1013469;
     
  2. Cross RW, Prasad AN, Turcinovic J, Borisevich V, Agans KN, Woolsey C, Deer DJ, Harrison MB, O'Toole R, Villasante-Tezanos A, Velasquez-Reyes J, Dobias NS, Connor JH, Fenton KA, Geisbert TW. Lassa fever in African green monkeys: Clinical disease and fatal outcome are associated with systemic viral dissemination and inflammation. Cell Rep Med. 2025 Aug 19; 6(8):102263. PMID: 40763738; PMCID: PMC12432369; DOI: 10.1016/j.xcrm.2025.102263;
     
  3. Velasquez-Reyes JM, Schaeffer B, Curry SR, Overbeck V, Sher-Jan C, Taylor BP, Turcinovic J, Kuppalli K, Connor JH, Hanage WP. Characterisation of a persistent SARS-CoV-2 infection lasting more than 750 days in a person living with HIV: a genomic analysis. Lancet Microbe. 2025 Sep; 6(9):101122. PMID: 40706602
     
  4. LaVerriere E, Behar S, Sher-Jan C, Liang YM, Sagar M, Connor JH. Genomic Epidemiology of Respiratory Syncytial Virus in a New England Hospital System, 2024. Open Forum Infect Dis. 2025 Jun; 12(6):ofaf334.View Related Profiles. PMID: 40567998; PMCID: PMC12188213; DOI: 10.1093/ofid/ofaf334;
     
  5. Nguyen MA, Williams C, Gard AL, Connor JH. Endothelial growth media components alter SARS-CoV-2 spike-directed growth kinetics. J Virol Methods. 2025 Apr; 333:115111. PMID: 39880099
     
  6. Lin H, Seitz S, Tan Y, Lugagne JB, Wang L, Ding G, He H, Rauwolf TJ, Dunlop MJ, Connor JH, Porco JA, Tian L, Cheng JX. Label-free nanoscopy of cell metabolism by ultrasensitive reweighted visible stimulated Raman scattering. Nat Methods. 2025 May; 22(5):1040-1050.View Related Profiles. PMID: 39820753; PMCID: PMC12074879; DOI: 10.1038/s41592-024-02575-1;
     
  7. Keiser PT, Zhang W, Ricca M, Wacquiez A, Grimins A, Cencic R, Patten JJ, Shah P, Padilha E, Connor JH, Pelletier J, Lyons SM, Saeed M, Brown LE, Porco JA, Davey RA. Amidino-rocaglates (ADRs), a class of synthetic rocaglates, are potent inhibitors of SARS-CoV-2 replication through inhibition of viral protein synthesis. Antiviral Res. 2024 Oct; 230:105976.View Related Profiles. PMID: 39117283; PMCID: PMC11434215; DOI: 10.1016/j.antiviral.2024.105976;
     
  8. Ross SJ, Hume AJ, Olejnik J, Turcinovic J, Honko AN, McKay LGA, Connor JH, Griffiths A, Mühlberger E, Cifuentes D. Low-Input, High-Resolution 5' Terminal Filovirus RNA Sequencing with ViBE-Seq. Viruses. 2024 Jul 01; 16(7).View Related Profiles. PMID: 39066227; PMCID: PMC11281615; DOI: 10.3390/v16071064;
     
  9. Hume AJ, Deeney DJ, Smetana JS, Turcinovic J, Connor JH, Belfort M, Mühlberger E, Lennon CW. Improved protein splicing through viral passaging. mBio. 2024 Jun 12; 15(6):e0098424.View Related Profiles. PMID: 38780266; PMCID: PMC11237716; DOI: 10.1128/mbio.00984-24;
     
  10. Hartmann JA, Cardoso MR, Talarico MCR, Kenney DJ, Leone MR, Reese DC, Turcinovic J, O'Connell AK, Gertje HP, Marino C, Ojeda PE, De Paula EV, Orsi FA, Velloso LA, Cafiero TR, Connor JH, Ploss A, Hoelzemer A, Carrington M, Barczak AK, Crossland NA, Douam F, Boucau J, Garcia-Beltran WF. Evasion of NKG2D-mediated cytotoxic immunity by sarbecoviruses. Cell. 2024 May 09; 187(10):2393-2410.e14.View Related Profiles. PMID: 38653235; PMCID: PMC11088510; DOI: 10.1016/j.cell.2024.03.026;
     
Showing 10 of 155 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 155 publications over 29 distinct years, with a maximum of 15 publications in 2017

YearPublications
19961
19971
19983
19992
20004
20013
20022
20031
20042
20051
20064
20072
20083
20092
20105
20116
20126
20134
20148
20156
20166
201715
201811
20206
202113
202213
202311
20248
20256


CDC confirms first severe human case of bird flu in U.S.

The Washington Post 12/18/2024

Is COVID-19 Still a Pandemic?

The Brink 3/4/2024

Were college campuses COVID hot spots? Boston University study shows that test-trace-isolate strategies prevented spread for most COVID cases

Boston Herald 10/17/2023

Public health interventions prevented transmission within BU most SARS-CoV-2 cases

SCIENMAG 10/17/2023

Public health interventions prevented transmission within Boston University of most SARS-CoV-2 cases, finds study

Medical Xpress 10/17/2023

Best of The Brink 2022: BU’s Most-Read Science and Research Stories

BU Today 12/13/2022

COVID-19's Lessons for Future Pandemics

Harvard Medical School 11/17/2022

Coronavirus Alert: U.S. Cases Dip but Deaths Slowly Rising, Michigan Governor Whitmer Tests Positive, and More

Everyday Health 8/10/2022

Study: In-Person Learning Did Not Spread COVID In Classrooms

WBZ News Radio 8/9/2022

BU’s Mask and Vaccination Mandates Prevented Spread of COVID in Classes, Research Finds

BU Today 8/8/2022

Masked, Vaccinated Students Didn’t Catch Covid in Classrooms

Bloomberg 8/5/2022

Masks and mandatory vaccinations ‘halt class Covid transmission’

Times Higher Education 8/5/2022

Boston University study finds in-person learning did not increase COVID-19 transmission

WCVB 8/5/2022

Monkeypox Cases—and Concern—Climbing

BU Today 8/3/2022

How new Boston University School of Medicine study supports current COVID-19 guidelines

WCVB 6/27/2022

A Bellwether for COVID-19

Harvard Medical School 6/8/2022

How Worried Should We Be about Monkeypox?

BU Today 5/25/2022

Is Five Days of COVID Isolation Enough? New BU Study Has Some Answers

BU Today 4/12/2022

BU Scientists Are Prepared to Detect Omicron—and Other Variants

BU Today 12/9/2021

The Omicron Variant Is a Mystery. Here’s How Science Will Solve It

Wired 12/1/2021

Those infected with the Delta variant may be carrying more than a thousand times more viral particles than prior variants

Genetic Literacy Project 8/17/2021

COVID-19 Delta Variant Is 'More Infectious and Replicates Faster', New Study Might Reveal Why

Science Times 7/24/2021

Where did COVID-19 come from?

USA Today 1/16/2021

What Does Pfizer’s Vaccine News Mean for the Coronavirus Pandemic?

BU Today 11/10/2020

Recovered Holyoke Soldiers’ Home vet testing positive for coronavirus raises questions about reinfection

The Boston Herald 7/28/2020

Coronavirus Immunity Studies ‘Encouraging’ For Short-Term Protection From Reinfection, Says BU Immunologist

The Boston Herald 5/5/2020

Mass. Hospitals To Launch Trial Of Japanese Drug Aimed At Fighting COVID-19

WBUR 4/9/2020

Mass. Hospitals To Launch Trail Of Japanese Drug Aimed At Fighting COVID-19

WBUR 4/9/2020

Antibodies found in blood of recovered coronavirus patients could offer a path to treatment

The Boston Herald 3/31/2020

Boston University Researchers Work To Develop Quick Coronavirus Test For Doctors’ Offices

CBS Boston 3/12/2020

Coronavirus Declared a Pandemic, Cases in U.S. and Massachusetts Continue to Rise

The Boston Herald 3/11/2020

COVID-19: What You Should And Shouldn’t Do Now

Futurity 3/4/2020

Coronavirus Is Coming: Dos and Don’ts for Protecting Yourself

BU Today 2/27/2020

Coronavirus Declared a Global Health Emergency by World Health Organization

The Boston Herald 1/30/2020

Robots on the March

Bloomberg Baystate Business 1/24/2020

Why Doesn’t The Flu Freak Us Out More?

Futurity 12/3/2019

Should We Fear The Flu More Than EEE?

BU Today 12/2/2019

Boston Medical Center Pathogen Specialist Hails New Ebola Study Hinting at Possible Cure

Boston Globe 8/12/2019

Amid High-Profile Outbreaks, Benefit of Widespread Asymptomatic Screening Remains Low

Contagion Live 2/14/2019

Spotting Ebola in the Crowd

BU Today 1/28/2019

Rapid diagnostic test detects Ebola, malaria in the field

MedTech DIVE 12/14/2018

New Portable Diagnostic Test For Ebola And Malaria Has Big Public Health Implications

WBUR 12/13/2018

Point-of-care test differentiates Ebola from similar diseases in 30 minutes

Healio ITJ 12/13/2018

Researchers Develop Portable Diagnostic Test For Ebola And Malaria

AAAS 12/12/2018

New Field Test Discerns Between Ebola and Lookalike Fevers

MDDI 12/12/2018

BU Experts on New Ebola Outbreak in Democratic Republic of the Congo

BU Today 5/31/2018

Available to Mentor as: (Review Mentor Role Definitions):
  • Advisor
  • Co-Mentor or Peer Mentor
Contact for Mentoring:

620 Albany Street
Boston MA 02118
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