John H. Connor, PhD

My laboratory studies the virus-host interaction. We take a variety of approaches from genetic to systems biology to biochemistry and molecular biology. We are studying how viruses take over the cellular protein synthesis apparatus, how cells effectively fight virus infection, and how the host responds to infection with viruses that cause hemorrhagic fever.

Faculty
Boston University
National Emerging Infectious Disease Lab


Member
Boston University
Genome Science Institute


Member
Boston University
Bioinformatics Graduate Program


Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Graduate Medical Sciences




Determinants of COVID19-induced venous thrombosis and targeted therapy assessed with bioengineered vein-chip
05/01/2021 - 04/30/2025 (PI)
NIH/National Heart, Lung, and Blood Institute
1R01HL157790-01

Advancement of a poxvirus inhibitor
03/12/2020 - 02/28/2025 (PI)
NIH/National Institute of Allergy & Infectious Diseases
5R01AI151559-02

Antimicrobial Surface Coatings to Reduce COVID-19 Spread
11/18/2020 - 08/24/2022 (Subcontract PI)
Physical Sciences, Inc. DOD Air Force


In Vitro Evaluation and Validation of the Virex Test strips and Devices
01/01/2021 - 12/31/2021 (PI)
Virex Health, Inc


B-BIC RADX-Rad: Unlu (BU) Subcontract
12/21/2020 - 11/30/2021 (Co-Investigator)
The Brigham and Women's Hospital, Inc. NIH NHLBI
4U54HL119145-08

Genetic probing of residues involved in ebolavirus glycoprotein entry
07/01/2018 - 06/30/2021 (PI)
NIH/National Institute of Allergy & Infectious Diseases
5R21AI135517-02

SBIR Phase II: High-Throughput and Scalable Nanoparticle Characterization for Life Sciences Applications
08/15/2018 - 07/31/2020 (Subcontract PI)
Nanoview Diagnostics Inc. National Science Fdn
IIP-1831192

role for polyamines in Ebola Virus Replication
02/01/2016 - 01/31/2019 (PI)
NIH/National Institute of Allergy & Infectious Diseases
5R21AI121933-02

Assessment of infection route and vulnerability of neural precursor classes to Zika virus
09/30/2016 - 08/31/2018 (Multi-PI)
PI: John H. Connor, PhD
NIH/National Institute of Neurological Disorders & Stroke
5R21NS101151-02

Development of Near Real-Time, Multiplexed Diagnostics for Viral Hemorrhagic Fever
08/01/2011 - 07/31/2018 (PI)
NIH/National Institute of Allergy & Infectious Diseases
5R01AI096159-05

Showing 10 of 23 results. Show All Results


Title


Yr Title Project-Sub Proj Pubs
2021 Determinants of COVID19-induced venous thrombosis and targeted therapy assessed with bioengineered vein-chip 1R01HL157790-01
2021 Advancement of poxvirus inhibitor 5R01AI151559-02
2020 Advancement of poxvirus inhibitor 1R01AI151559-01
2020 Advancement of poxvirus inhibitor 1R01AI151559-01
2019 Genetic probing of residues involved in ebolavirus glycoprotein entry 5R21AI135517-02 1
2018 Genetic probing of residues involved in ebolavirus glycoprotein entry 1R21AI135517-01 1
2017 Assessment of infection route and vulnerability of neural precursor classes to Zika virus 5R21NS101151-02 3
2017 Role for polyamines in Ebola Virus Replication 5R21AI121933-02 7
2016 Assessment of infection route and vulnerability of neural precursor classes to Zika virus 1R21NS101151-01 3
2016 Role for polyamines in Ebola Virus Replication 1R21AI121933-01 7
Showing 10 of 23 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Shelton SM, Soucy AR, Kurzion R, Zeldich E, Connor JH, Haydar TF. Forebrain neural precursor cells are differentially vulnerable to Zika virus infection. eNeuro. 2021 Jul 16.View Related Profiles. PMID: 34272257
     
  2. Chen DY, Khan N, Close BJ, Goel RK, Blum B, Tavares AH, Kenney D, Conway HL, Ewoldt JK, Chitalia VC, Crossland NA, Chen CS, Kotton DN, Baker SC, Fuchs SY, Connor JH, Douam F, Emili A, Saeed M. SARS-CoV-2 disrupts proximal elements in the JAK-STAT pathway. J Virol. 2021 Jul 14; JVI0086221.View Related Profiles. PMID: 34260266
     
  3. Zhang Y, Yurdakul C, Devaux AJ, Wang L, Xu XG, Connor JH, Ünlü MS, Cheng JX. Vibrational Spectroscopic Detection of a Single Virus by Mid-Infrared Photothermal Microscopy. Anal Chem. 2021 03 02; 93(8):4100-4107. PMID: 33596049
     
  4. Bhattacharya B, Xiao S, Chatterjee S, Urbanowski M, Ordonez A, Ihms EA, Agrahari G, Lun S, Berland R, Pichugin A, Gao Y, Connor J, Ivanov AR, Yan BS, Kobzik L, Koo BB, Jain S, Bishai W, Kramnik I. The integrated stress response mediates necrosis in murine Mycobacterium tuberculosis granulomas. J Clin Invest. 2021 02 01; 131(3).View Related Profiles. PMID: 33301427; PMCID: PMC7843230; DOI: 10.1172/JCI130319;
     
  5. Strampe J, Asogun DA, Speranza E, Pahlmann M, Soucy A, Bockholt S, Pallasch E, Becker-Ziaja B, Duraffour S, Bhadelia N, Ighodalo Y, Oyakhilome J, Omomoh EO, Olokor T, Adomeh DI, Ikponwonsa O, Aire C, Tobin E, Akpede N, Okokhere PO, Okogbenin SA, Akpede GO, Muñoz-Fontela C, Ogbaini-Emovon E, Günther S, Connor JH, Oestereich L. Factors associated with progression to death in patients with Lassa fever in Nigeria: an observational study. Lancet Infect Dis. 2021 06; 21(6):876-886.View Related Profiles. PMID: 33484646; PMCID: PMC8212868; DOI: 10.1016/S1473-3099(20)30737-4;
     
  6. Seymour E, Ünlü NL, Carter EP, Connor JH, Ünlü MS. Configurable Digital Virus Counter on Robust Universal DNA Chips. ACS Sens. 2021 01 22; 6(1):229-237.View Related Profiles. PMID: 33427442
     
  7. Ma Q, Srivastav SP, Gamez S, Dayama G, Feitosa-Suntheimer F, Patterson EI, Johnson RM, Matson EM, Gold AS, Brackney DE, Connor JH, Colpitts TM, Hughes GL, Rasgon JL, Nolan T, Akbari OS, Lau NC. A mosquito small RNA genomics resource reveals dynamic evolution and host responses to viruses and transposons. Genome Res. 2021 Mar; 31(3):512-528.View Related Profiles. PMID: 33419731; PMCID: PMC7919454; DOI: 10.1101/gr.265157.120;
     
  8. Hekman RM, Hume AJ, Goel RK, Abo KM, Huang J, Blum BC, Werder RB, Suder EL, Paul I, Phanse S, Youssef A, Alysandratos KD, Padhorny D, Ojha S, Mora-Martin A, Kretov D, Ash PEA, Verma M, Zhao J, Patten JJ, Villacorta-Martin C, Bolzan D, Perea-Resa C, Bullitt E, Hinds A, Tilston-Lunel A, Varelas X, Farhangmehr S, Braunschweig U, Kwan JH, McComb M, Basu A, Saeed M, Perissi V, Burks EJ, Layne MD, Connor JH, Davey R, Cheng JX, Wolozin BL, Blencowe BJ, Wuchty S, Lyons SM, Kozakov D, Cifuentes D, Blower M, Kotton DN, Wilson AA, Mühlberger E, Emili A. Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2. Mol Cell. 2021 Jan 07; 81(1):212.View Related Profiles. PMID: 33417854; PMCID: PMC7831449; DOI: 10.1016/j.molcel.2020.12.028;
     
  9. Hekman RM, Hume AJ, Goel RK, Abo KM, Huang J, Blum BC, Werder RB, Suder EL, Paul I, Phanse S, Youssef A, Alysandratos KD, Padhorny D, Ojha S, Mora-Martin A, Kretov D, Ash PEA, Verma M, Zhao J, Patten JJ, Villacorta-Martin C, Bolzan D, Perea-Resa C, Bullitt E, Hinds A, Tilston-Lunel A, Varelas X, Farhangmehr S, Braunschweig U, Kwan JH, McComb M, Basu A, Saeed M, Perissi V, Burks EJ, Layne MD, Connor JH, Davey R, Cheng JX, Wolozin BL, Blencowe BJ, Wuchty S, Lyons SM, Kozakov D, Cifuentes D, Blower M, Kotton DN, Wilson AA, Mühlberger E, Emili A. Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2. Mol Cell. 2020 12 17; 80(6):1104-1122.e9.View Related Profiles. PMID: 33259812; PMCID: PMC7674017; DOI: 10.1016/j.molcel.2020.11.028;
     
  10. Chen DY, Khan N, Close BJ, Goel RK, Blum B, Tavares AH, Kenney D, Conway HL, Ewoldt JK, Kapell S, Chitalia VC, Crossland NA, Chen CS, Kotton DN, Baker SC, Connor JH, Douam F, Emili A, Saeed M. SARS-CoV-2 desensitizes host cells to interferon through inhibition of the JAK-STAT pathway. bioRxiv. 2020 Oct 28.View Related Profiles. PMID: 33140044; PMCID: PMC7605551; DOI: 10.1101/2020.10.27.358259;
     
Showing 10 of 112 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 112 publications over 25 distinct years, with a maximum of 15 publications in 2017

YearPublications
19961
19971
19983
19992
20004
20013
20022
20031
20042
20051
20064
20072
20083
20092
20105
20116
20126
20134
20148
20156
20166
201715
201811
20206
20218


Recent (within 3 months)

Those infected with the Delta variant may be carrying more than a thousand times more viral particles than prior variants

Genetic Literacy Project 8/17/2021

COVID-19 Delta Variant Is 'More Infectious and Replicates Faster', New Study Might Reveal Why

Science Times 7/24/2021

Older

Where did COVID-19 come from?

USA Today 1/16/2021

What Does Pfizer’s Vaccine News Mean for the Coronavirus Pandemic?

BU Today 11/10/2020

Recovered Holyoke Soldiers’ Home vet testing positive for coronavirus raises questions about reinfection

The Boston Herald 7/28/2020

Coronavirus immunity studies ‘encouraging’ for short-term protection from reinfection, says BU immunologist

The Boston Herald 5/6/2020

Coronavirus Immunity Studies ‘Encouraging’ For Short-Term Protection From Reinfection, Says BU Immunologist

The Boston Herald 5/5/2020

Mass. Hospitals To Launch Trial Of Japanese Drug Aimed At Fighting COVID-19

WBUR 4/9/2020

Mass. Hospitals To Launch Trail Of Japanese Drug Aimed At Fighting COVID-19

WBUR 4/9/2020

Antibodies found in blood of recovered coronavirus patients could offer a path to treatment

The Boston Herald 3/31/2020

Boston University Researchers Work To Develop Quick Coronavirus Test For Doctors’ Offices

CBS Boston 3/12/2020

Coronavirus Declared a Pandemic, Cases in U.S. and Massachusetts Continue to Rise

The Boston Herald 3/11/2020

COVID-19: What You Should And Shouldn’t Do Now

Futurity 3/4/2020

Coronavirus Is Coming: Dos and Don’ts for Protecting Yourself

BU Today 2/27/2020

Coronavirus Declared a Global Health Emergency by World Health Organization

The Boston Herald 1/30/2020

Robots on the March

Bloomberg Baystate Business 1/24/2020

Why Doesn’t The Flu Freak Us Out More?

Futurity 12/3/2019

Should We Fear The Flu More Than EEE?

BU Today 12/2/2019

Boston Medical Center Pathogen Specialist Hails New Ebola Study Hinting at Possible Cure

Boston Globe 8/12/2019

Amid High-Profile Outbreaks, Benefit of Widespread Asymptomatic Screening Remains Low

Contagion Live 2/14/2019

Spotting Ebola in the Crowd

BU Today 1/28/2019

Rapid diagnostic test detects Ebola, malaria in the field

MedTech DIVE 12/14/2018

New Portable Diagnostic Test For Ebola And Malaria Has Big Public Health Implications

WBUR 12/13/2018

Point-of-care test differentiates Ebola from similar diseases in 30 minutes

Healio ITJ 12/13/2018

Researchers Develop Portable Diagnostic Test For Ebola And Malaria

AAAS 12/12/2018

New Field Test Discerns Between Ebola and Lookalike Fevers

MDDI 12/12/2018

BU Experts on New Ebola Outbreak in Democratic Republic of the Congo

BU Today 5/31/2018

Available to Mentor as: (Review Mentor Role Definitions):
  • Advisor
  • Co-Mentor or Peer Mentor
Contact for Mentoring:

72 E. Concord St Housman (R)
Boston MA 02118
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