Markus Bosmann | Profiles RNS

Markus Bosmann, MD

Associate Professor

Boston University Chobanian & Avedisian School of Medicine

Medicine

Pulmonary, Allergy, Sleep & Critical Care Medicine

MD, Goethe University Frankfurt

Websites

	Pulmonary, Allergy, Sleep, and Critical Care Medicine Faculty
	UROP

ORCID : 0000-0003-2773-1033

Dr. Bosmann is an Associate Professor at the Chobanian and Avedisian School of Medicine. His research interests include pulmonary disorders and their connections to innate immunity, host-pathogen interactions, and inflammation.

Associate Professor
Boston University Chobanian & Avedisian School of Medicine
Pathology & Laboratory Medicine

Member
Boston University
Pulmonary Center

Member
Boston University
Evans Center for Interdisciplinary Biomedical Research

Member
Boston University
Genome Science Institute

Graduate Faculty (Primary Mentor of Grad Students)
Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences

BU Research

Interleukin-27 in host response to Legionella infection
07/01/2023 - 06/30/2027 (PI)
NIH/National Heart, Lung, and Blood Institute
1R01HL166588-01A1

Bacterial polyphosphates in sepsis
02/22/2021 - 01/31/2025 (PI)
NIH/National Institute of Allergy & Infectious Diseases
5R01AI153613-03

Role reversal of MAVS in bacterial sepsis
08/15/2018 - 06/30/2024 (PI)
NIH/National Heart, Lung, and Blood Institute
5R01HL141513-05

New genetic models for C5a receptors
07/01/2018 - 06/30/2024 (PI)
NIH/National Heart, Lung, and Blood Institute
5R01HL139641-05

Therapeutic effects of NAPc2 in SARS-CoV-2 infection of K18-hACE2 transgenic mice
03/15/2021 - 03/31/2022 (Multi-PI)
PI: Markus Bosmann, MD
ARCA Biopharma, Inc.

Anti-complement therapy: a drug target for COVID-19-induced inflammation and coagulation
03/01/2021 - 02/28/2022 (Key Person / Mentor)
PI: Saravanan Subramaniam, PhD
Aniara Diagnostica

Title

Yr	Title	Project-Sub Proj	Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Zelaya H, Grunz K, Nguyen TS, Habibi A, Witzler C, Reyda S, Gonzalez-Menendez I, Quintanilla-Martinez L, Bosmann M, Weiler H, Ruf W. Nucleic acid sensing promotes inflammatory monocyte migration through biased coagulation factor VIIa signaling. Blood. 2024 Mar 07; 143(10):845-857. PMID: 38096370

Dremova O, Mimmler M, Paeslack N, Khuu MP, Gao Z, Bosmann M, Garo LP, Schön N, Mechler A, Beneich Y, Rebling V, Mann A, Pontarollo G, Kiouptsi K, Reinhardt C. Sterility testing of germ-free mouse colonies. Front Immunol. 2023; 14:1275109. PMID: 38022683; PMCID: PMC10662041; DOI: 10.3389/fimmu.2023.1275109;

Riehl DR, Sharma A, Roewe J, Murke F, Ruppert C, Eming SA, Bopp T, Kleinert H, Radsak MP, Colucci G, Subramaniam S, Reinhardt C, Giebel B, Prinz I, Guenther A, Strand D, Gunzer M, Waisman A, Ward PA, Ruf W, Schäfer K, Bosmann M. Externalized histones fuel pulmonary fibrosis via a platelet-macrophage circuit of TGFß1 and IL-27. Proc Natl Acad Sci U S A. 2023 Oct 03; 120(40):e2215421120. PMID: 37756334; PMCID: PMC10556605; DOI: 10.1073/pnas.2215421120;

Pontarollo G, Kollar B, Mann A, Khuu MP, Kiouptsi K, Bayer F, Brandão I, Zinina VV, Hahlbrock J, Malinarich F, Mimmler M, Bhushan S, Marini F, Ruf W, Belheouane M, Baines JF, Endres K, Reba SM, Raker VK, Deppermann C, Welsch C, Bosmann M, Soshnikova N, Chassaing B, Bergentall M, Sommer F, Bäckhed F, Reinhardt C. Author Correction: Commensal bacteria weaken the intestinal barrier by suppressing epithelial neuropilin-1 and Hedgehog signaling. Nat Metab. 2023 Sep; 5(9):1639. PMID: 37697057; PMCID: PMC10513928; DOI: 10.1038/s42255-023-00901-z;

Pontarollo G, Kollar B, Mann A, Khuu MP, Kiouptsi K, Bayer F, Brandão I, Zinina VV, Hahlbrock J, Malinarich F, Mimmler M, Bhushan S, Marini F, Ruf W, Belheouane M, Baines JF, Endres K, Reba SM, Raker VK, Deppermann C, Welsch C, Bosmann M, Soshnikova N, Chassaing B, Bergentall M, Sommer F, Bäckhed F, Reinhardt C. Commensal bacteria weaken the intestinal barrier by suppressing epithelial neuropilin-1 and Hedgehog signaling. Nat Metab. 2023 Jul; 5(7):1174-1187. PMID: 37414930; PMCID: PMC10365997; DOI: 10.1038/s42255-023-00828-5;

Krenzlin V, Schöche J, Walachowski S, Reinhardt C, Radsak MP, Bosmann M. Immunomodulation of neutrophil granulocyte functions by bacterial polyphosphates. Eur J Immunol. 2023 May; 53(5):e2250339.View Related Profiles.

Bosmann, Markus
Walachowski, Sarah

PMID: 36959687; PMCID: PMC10666560; DOI: 10.1002/eji.202250339;

Bosmann, Markus
Walachowski, Sarah

PMID: 36959687; PMCID: PMC10666560; DOI: 10.1002/eji.202250339;

Chen DY, Chin CV, Kenney D, Tavares AH, Khan N, Conway HL, Liu G, Choudhary MC, Gertje HP, O'Connell AK, Adams S, Kotton DN, Herrmann A, Ensser A, Connor JH, Bosmann M, Li JZ, Gack MU, Baker SC, Kirchdoerfer RN, Kataria Y, Crossland NA, Douam F, Saeed M. Spike and nsp6 are key determinants of SARS-CoV-2 Omicron BA.1 attenuation. Nature. 2023 Mar; 615(7950):143-150.View Related Profiles.

Kotton, Darrell
Douam, Florian
Connor, John
Bosmann, Markus
Saeed, Mohsan
Khan, Nazimuddin
Crossland, Nicholas
Kataria, Yachana

PMID: 36630998

Chen DY, Kenney D, Chin CV, Tavares AH, Khan N, Conway HL, Liu G, Choudhary MC, Gertje HP, O'Connell AK, Kotton DN, Herrmann A, Ensser A, Connor JH, Bosmann M, Li JZ, Gack MU, Baker SC, Kirchdoerfer RN, Kataria Y, Crossland NA, Douam F, Saeed M. Role of spike in the pathogenic and antigenic behavior of SARS-CoV-2 BA.1 Omicron. bioRxiv. 2023 Jan 10.View Related Profiles.

Kotton, Darrell
Douam, Florian
Connor, John
Bosmann, Markus
Saeed, Mohsan
Khan, Nazimuddin
Crossland, Nicholas
Kataria, Yachana

PMID: 36263066; PMCID: PMC9580375; DOI: 10.1101/2022.10.13.512134;

Roewe J, Walachowski S, Sharma A, Berthiaume KA, Reinhardt C, Bosmann M. Bacterial polyphosphates induce CXCL4 and synergize with complement anaphylatoxin C5a in lung injury. Front Immunol. 2022; 13:980733.View Related Profiles.

Bosmann, Markus
Walachowski, Sarah

PMID: 36405694; PMCID: PMC9669059; DOI: 10.3389/fimmu.2022.980733;

Showing 10 of 78 results. Show More

Subramaniam S, Kothari H, Bosmann M. Tissue factor in COVID-19-associated coagulopathy. Thromb Res. 2022 Dec; 220:35-47.View Related Profiles.

Bosmann, Markus
Subramaniam, Saravanan

PMID: 36265412; PMCID: PMC9525243; DOI: 10.1016/j.thromres.2022.09.025;

Krenzlin V, Roewe J, Strueve M, Martínez-Negro M, Sharma A, Reinhardt C, Morsbach S, Bosmann M. Bacterial-Type Long-Chain Polyphosphates Bind Human Proteins in the Phosphatidylinositol Signaling Pathway. Thromb Haemost. 2022 Nov; 122(11):1943-1947. PMID: 35909349; PMCID: PMC9798540; DOI: 10.1055/s-0042-1751280;

Chaudhary N, Jayaraman A, Reinhardt C, Campbell JD, Bosmann M. A single-cell lung atlas of complement genes identifies the mesothelium and epithelium as prominent sources of extrahepatic complement proteins. Mucosal Immunol. 2022 May; 15(5):927-939.View Related Profiles.

Jayaraman, Archana
Campbell, Joshua
Bosmann, Markus
Chaudhary, Neha

PMID: 35672453; PMCID: PMC9173662; DOI: 10.1038/s41385-022-00534-7;

Kenney DJ, O'Connell AK, Turcinovic J, Montanaro P, Hekman RM, Tamura T, Berneshawi AR, Cafiero TR, Al Abdullatif S, Blum B, Goldstein SI, Heller BL, Gertje HP, Bullitt E, Trachtenberg AJ, Chavez E, Nono ET, Morrison C, Tseng AE, Sheikh A, Kurnick S, Grosz K, Bosmann M, Ericsson M, Huber BR, Saeed M, Balazs AB, Francis KP, Klose A, Paragas N, Campbell JD, Connor JH, Emili A, Crossland NA, Ploss A, Douam F. Humanized mice reveal a macrophage-enriched gene signature defining human lung tissue protection during SARS-CoV-2 infection. Cell Rep. 2022 Apr 19; 39(3):110714.View Related Profiles.

Emili, Andrew
Blum, Benjamin
Huber, Bertrand
Bullitt, Esther
Douam, Florian
Connor, John
Campbell, Joshua
Bosmann, Markus
Saeed, Mohsan
Crossland, Nicholas

PMID: 35421379; PMCID: PMC8977517; DOI: 10.1016/j.celrep.2022.110714;

Sharma A, Noon JB, Kontodimas K, Garo LP, Platten J, Quinton LJ, Urban JF, Reinhardt C, Bosmann M. IL-27 Enhances ?d T Cell-Mediated Innate Resistance to Primary Hookworm Infection in the Lungs. J Immunol. 2022 Apr 15; 208(8):2008-2018.View Related Profiles.

Quinton, Lee
Bosmann, Markus

PMID: 35354611; PMCID: PMC9012701; DOI: 10.4049/jimmunol.2000945;

Carossino M, Kenney D, O'Connell AK, Montanaro P, Tseng AE, Gertje HP, Grosz KA, Ericsson M, Huber BR, Kurnick SA, Subramaniam S, Kirkland TA, Walker JR, Francis KP, Klose AD, Paragas N, Bosmann M, Saeed M, Balasuriya UBR, Douam F, Crossland NA. Fatal Neurodissemination and SARS-CoV-2 Tropism in K18-hACE2 Mice Is Only Partially Dependent on hACE2 Expression. Viruses. 2022 03 05; 14(3).View Related Profiles.

Huber, Bertrand
Douam, Florian
Bosmann, Markus
Saeed, Mohsan
Crossland, Nicholas
Subramaniam, Saravanan

PMID: 35336942; PMCID: PMC8955233; DOI: 10.3390/v14030535;

Sanders NL, Martin IMC, Sharma A, Jones MR, Quinton LJ, Bosmann M, Mizgerd JP. Neutrophil Extracellular Traps as an Exacerbating Factor in Bacterial Pneumonia. Infect Immun. 2022 03 17; 90(3):e0049121.View Related Profiles.

Mizgerd, Joseph
Quinton, Lee
Bosmann, Markus
Jones, Matthew

PMID: 35130455; PMCID: PMC8929384; DOI: 10.1128/iai.00491-21;

Sharma A, Kontodimas K, Bosmann M. The MAVS Immune Recognition Pathway in Viral Infection and Sepsis. Antioxid Redox Signal. 2021 12; 35(16):1376-1392. PMID: 34348482; PMCID: PMC8817698; DOI: 10.1089/ars.2021.0167;

Helmstädter J, Keppeler K, Aust F, Küster L, Frenis K, Filippou K, Vujacic-Mirski K, Tsohataridis S, Kalinovic S, Kröller-Schön S, Oelze M, Bosmann M, Münzel T, Daiber A, Steven S. GLP-1 Analog Liraglutide Improves Vascular Function in Polymicrobial Sepsis by Reduction of Oxidative Stress and Inflammation. Antioxidants (Basel). 2021 Jul 23; 10(8). PMID: 34439423; PMCID: PMC8388926; DOI: 10.3390/antiox10081175;

Subramaniam S, Ruf W, Bosmann M. Advocacy of targeting protease-activated receptors in severe coronavirus disease 2019. Br J Pharmacol. 2022 May; 179(10):2086-2099.View Related Profiles.

Bosmann, Markus
Subramaniam, Saravanan

PMID: 34235728; PMCID: PMC8794588; DOI: 10.1111/bph.15587;

Sharma A, Kontodimas K, Bosmann M. Nanomedicine: A Diagnostic and Therapeutic Approach to COVID-19. Front Med (Lausanne). 2021; 8:648005. PMID: 34150793; PMCID: PMC8211875; DOI: 10.3389/fmed.2021.648005;

Bosmann M. Complement control for COVID-19. Sci Immunol. 2021 05 25; 6(59). PMID: 34035117; PMCID: PMC8432947; DOI: 10.1126/sciimmunol.abj1014;

Leister H, Luu M, Staudenraus D, Lopez Krol A, Mollenkopf HJ, Sharma A, Schmerer N, Schulte LN, Bertrams W, Schmeck B, Bosmann M, Steinhoff U, Visekruna A. Pro- and Antitumorigenic Capacity of Immunoproteasomes in Shaping the Tumor Microenvironment. Cancer Immunol Res. 2021 06; 9(6):682-692. PMID: 33707310; PMCID: PMC8355016; DOI: 10.1158/2326-6066.CIR-20-0492;

Carossino M, Montanaro P, O'Connell A, Kenney D, Gertje H, Grosz KA, Kurnick SA, Bosmann M, Saeed M, Balasuriya UBR, Douam F, Crossland NA. Fatal neuroinvasion of SARS-CoV-2 in K18-hACE2 mice is partially dependent on hACE2 expression. bioRxiv. 2021 Jan 15.View Related Profiles.

Huber, Bertrand
Douam, Florian
Bosmann, Markus
Saeed, Mohsan
Crossland, Nicholas
Subramaniam, Saravanan

PMID: 33469581; PMCID: PMC7814818; DOI: 10.1101/2021.01.13.425144;

Ascher S, Wilms E, Pontarollo G, Kiouptsi K, Malinarich F, Kittner JM, Bosmann M, Jurk K, Reinhardt C. Response by Ascher et al to Letter Regarding Article, "Gut Microbiota Restricts NETosis in Acute Mesenteric Ischemia-Reperfusion Injury". Arterioscler Thromb Vasc Biol. 2021 01; 41(1):e74-e75. PMID: 33356371

Hansen M, Peltier J, Killy B, Amin B, Bodendorfer B, Härtlova A, Uebel S, Bosmann M, Hofmann J, Büttner C, Ekici AB, Kuttke M, Franzyk H, Foged C, Beer-Hammer S, Schabbauer G, Trost M, Lang R. Macrophage Phosphoproteome Analysis Reveals MINCLE-dependent and -independent Mycobacterial Cord Factor Signaling. Mol Cell Proteomics. 2019 Apr; 18(4):669-685. PMID: 33451650

Huang J, Hume AJ, Abo KM, Werder RB, Villacorta-Martin C, Alysandratos KD, Beermann ML, Simone-Roach C, Lindstrom-Vautrin J, Olejnik J, Suder EL, Bullitt E, Hinds A, Sharma A, Bosmann M, Wang R, Hawkins F, Burks EJ, Saeed M, Wilson AA, Mühlberger E, Kotton DN. SARS-CoV-2 Infection of Pluripotent Stem Cell-Derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response. Cell Stem Cell. 2020 12 03; 27(6):962-973.e7.View Related Profiles.

Hume, Adam
Wilson, Andrew
Kotton, Darrell
Muhlberger, Elke
Burks, Eric
Bullitt, Esther
Hawkins, Finn
Huang, Jessie
Olejnik, Judith
Bosmann, Markus
Saeed, Mohsan
Werder, Rhiannon Bree

PMID: 32979316; PMCID: PMC7500949; DOI: 10.1016/j.stem.2020.09.013;

Meissl K, Simonovic N, Amenitsch L, Witalisz-Siepracka A, Klein K, Lassnig C, Puga A, Vogl C, Poelzl A, Bosmann M, Dohnal A, Sexl V, Müller M, Strobl B. STAT1 Isoforms Differentially Regulate NK Cell Maturation and Anti-tumor Activity. Front Immunol. 2020; 11:2189. PMID: 33042133; PMCID: PMC7519029; DOI: 10.3389/fimmu.2020.02189;

Roewe J, Stavrides G, Strueve M, Sharma A, Marini F, Mann A, Smith SA, Kaya Z, Strobl B, Mueller M, Reinhardt C, Morrissey JH, Bosmann M. Bacterial polyphosphates interfere with the innate host defense to infection. Nat Commun. 2020 08 12; 11(1):4035. PMID: 32788578; PMCID: PMC7423913; DOI: 10.1038/s41467-020-17639-x;

Bosmann M. Complement Activation during Critical Illness: Current Findings and an Outlook in the Era of COVID-19. Am J Respir Crit Care Med. 2020 07 15; 202(2):163-165. PMID: 32437622; PMCID: PMC7365374; DOI: 10.1164/rccm.202005-1926ED;

Ascher S, Wilms E, Pontarollo G, Formes H, Bayer F, Müller M, Malinarich F, Grill A, Bosmann M, Saffarzadeh M, Brandão I, Groß K, Kiouptsi K, Kittner JM, Lackner KJ, Jurk K, Reinhardt C. Gut Microbiota Restricts NETosis in Acute Mesenteric Ischemia-Reperfusion Injury. Arterioscler Thromb Vasc Biol. 2020 09; 40(9):2279-2292. PMID: 32611241; PMCID: PMC7484055; DOI: 10.1161/ATVBAHA.120.314491;

Huang J, Hume AJ, Abo KM, Werder RB, Villacorta-Martin C, Alysandratos KD, Beermann ML, Simone-Roach C, Olejnik J, Suder EL, Bullitt E, Hinds A, Sharma A, Bosmann M, Wang R, Hawkins F, Burks EJ, Saeed M, Wilson AA, Mühlberger E, Kotton DN. SARS-CoV-2 Infection of Pluripotent Stem Cell-derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response. bioRxiv. 2020 Jun 30.View Related Profiles.

Hume, Adam
Wilson, Andrew
Kotton, Darrell
Muhlberger, Elke
Burks, Eric
Bullitt, Esther
Hawkins, Finn
Olejnik, Judith
Bosmann, Markus
Saeed, Mohsan
Werder, Rhiannon Bree

PMID: 32637964; PMCID: PMC7337394; DOI: 10.1101/2020.06.30.175695;

Bochenek ML, Leidinger C, Rosinus NS, Gogiraju R, Guth S, Hobohm L, Jurk K, Mayer E, Münzel T, Lankeit M, Bosmann M, Konstantinides S, Schäfer K. Activated Endothelial TGFß1 Signaling Promotes Venous Thrombus Nonresolution in Mice Via Endothelin-1: Potential Role for Chronic Thromboembolic Pulmonary Hypertension. Circ Res. 2020 01 17; 126(2):162-181. PMID: 31747868; PMCID: PMC7101077; DOI: 10.1161/CIRCRESAHA.119.315259;

Alflen A, Aranda Lopez P, Hartmann AK, Maxeiner J, Bosmann M, Sharma A, Platten J, Ries F, Beckert H, Ruf W, Radsak MP. Neutrophil extracellular traps impair fungal clearance in a mouse model of invasive pulmonary aspergillosis. Immunobiology. 2020 01; 225(1):151867. PMID: 31761474; PMCID: PMC7227411; DOI: 10.1016/j.imbio.2019.11.002;

Gawish R, Bulat T, Biaggio M, Lassnig C, Bago-Horvath Z, Macho-Maschler S, Poelzl A, Simonovic N, Prchal-Murphy M, Rom R, Amenitsch L, Ferrarese L, Kornhoff J, Lederer T, Svinka J, Eferl R, Bosmann M, Kalinke U, Stoiber D, Sexl V, Krmpotic A, Jonjic S, Müller M, Strobl B. Myeloid Cells Restrict MCMV and Drive Stress-Induced Extramedullary Hematopoiesis through STAT1. Cell Rep. 2019 02 26; 26(9):2394-2406.e5. PMID: 30811989; PMCID: PMC6447072; DOI: 10.1016/j.celrep.2019.02.017;

Sharma A, Steven S, Bosmann M. The pituitary gland prevents shock-associated death by controlling multiple inflammatory mediators. Biochem Biophys Res Commun. 2019 01 29; 509(1):188-193. PMID: 30579593; PMCID: PMC6541382; DOI: 10.1016/j.bbrc.2018.12.101;

Kröller-Schön S, Daiber A, Steven S, Oelze M, Frenis K, Kalinovic S, Heimann A, Schmidt FP, Pinto A, Kvandova M, Vujacic-Mirski K, Filippou K, Dudek M, Bosmann M, Klein M, Bopp T, Hahad O, Wild PS, Frauenknecht K, Methner A, Schmidt ER, Rapp S, Mollnau H, Münzel T. Crucial role for Nox2 and sleep deprivation in aircraft noise-induced vascular and cerebral oxidative stress, inflammation, and gene regulation. Eur Heart J. 2018 10 07; 39(38):3528-3539. PMID: 29905797; PMCID: PMC6174027; DOI: 10.1093/eurheartj/ehy333;

Alflen A, Prüfer S, Ebner K, Reuter S, Lopez PA, Scharrer I, Banno F, Stassen M, Schild H, Jurk K, Bosmann M, Beckert H, Radsak MP. Author Correction: ADAMTS-13 regulates neutrophil recruitment in a mouse model of invasive pulmonary aspergillosis. Sci Rep. 2018 Sep 26; 8(1):14599. PMID: 30254380; PMCID: PMC6156568; DOI: 10.1038/s41598-018-32187-7;

Schütz E, Bochenek ML, Riehl DR, Bosmann M, Münzel T, Konstantinides S, Schäfer K. Absence of transforming growth factor beta 1 in murine platelets reduces neointima formation without affecting arterial thrombosis. Thromb Haemost. 2017 Aug 31; 117(9):1782-1797. PMID: 28726976; DOI: 10.1160/TH17-02-0112;

Kiouptsi K, Grill A, Mann A, Döhrmann M, Lillich M, Jäckel S, Malinarich F, Formes H, Manukyan D, Subramaniam S, Khandagale A, Karwot C, Thal SC, Bosmann M, Scharrer I, Jurk K, Reinhardt C. Mice deficient in the anti-haemophilic coagulation factor VIII show increased von Willebrand factor plasma levels. PLoS One. 2017; 12(8):e0183590.View Related Profiles.

Bosmann, Markus
Subramaniam, Saravanan

PMID: 28837614; PMCID: PMC5570278; DOI: 10.1371/journal.pone.0183590;

Roewe J, Higer M, Riehl DR, Gericke A, Radsak MP, Bosmann M. Neuroendocrine Modulation of IL-27 in Macrophages. J Immunol. 2017 Oct 01; 199(7):2503-2514. PMID: 28835457

Alflen A, Prüfer S, Ebner K, Reuter S, Aranda Lopez P, Scharrer I, Banno F, Stassen M, Schild H, Jurk K, Bosmann M, Beckert H, Radsak MP. ADAMTS-13 regulates neutrophil recruitment in a mouse model of invasive pulmonary aspergillosis. Sci Rep. 2017 08 03; 7(1):7184. PMID: 28775254; PMCID: PMC5543100; DOI: 10.1038/s41598-017-07340-3;

Fattahi F, Kalbitz M, Malan EA, Abe E, Jajou L, Huber-Lang MS, Bosmann M, Russell MW, Zetoune FS, Ward PA. Complement-induced activation of MAPKs and Akt during sepsis: role in cardiac dysfunction. FASEB J. 2017 Sep; 31(9):4129-4139. PMID: 28572445; PMCID: PMC5572692; DOI: 10.1096/fj.201700140R;

Ward PA, Fattahi F, Bosmann M. New Insights into Molecular Mechanisms of Immune Complex-Induced Injury in Lung. Front Immunol. 2016; 7:86. PMID: 27014266; PMCID: PMC4783387; DOI: 10.3389/fimmu.2016.00086;

Taddonio MA, Dolgachev V, Bosmann M, Ward PA, Su G, Wang SC, Hemmila MR. Influence of lipopolysaccharide-binding protein on pulmonary inflammation in gram-negative pneumonia. Shock. 2015 Jun; 43(6):612-9. PMID: 25643011; PMCID: PMC4433570; DOI: 10.1097/SHK.0000000000000349;

Russkamp NF, Ruemmler R, Roewe J, Moore BB, Ward PA, Bosmann M. Experimental design of complement component 5a-induced acute lung injury (C5a-ALI): a role of CC-chemokine receptor type 5 during immune activation by anaphylatoxin. FASEB J. 2015 Sep; 29(9):3762-72. PMID: 25999468; PMCID: PMC4763927; DOI: 10.1096/fj.15-271635;

Kalbitz M, Grailer JJ, Fattahi F, Jajou L, Herron TJ, Campbell KF, Zetoune FS, Bosmann M, Sarma JV, Huber-Lang M, Gebhard F, Loaiza R, Valdivia HH, Jalife J, Russell MW, Ward PA. Role of extracellular histones in the cardiomyopathy of sepsis. FASEB J. 2015 May; 29(5):2185-93. PMID: 25681459; PMCID: PMC4415013; DOI: 10.1096/fj.14-268730;

Bosmann M, Russkamp NF, Strobl B, Roewe J, Balouzian L, Pache F, Radsak MP, van Rooijen N, Zetoune FS, Sarma JV, Núñez G, Müller M, Murray PJ, Ward PA. Interruption of macrophage-derived IL-27(p28) production by IL-10 during sepsis requires STAT3 but not SOCS3. J Immunol. 2014 Dec 01; 193(11):5668-77. PMID: 25348624; PMCID: PMC4239188; DOI: 10.4049/jimmunol.1302280;

Weber M, Rudolph B, Stein P, Yogev N, Bosmann M, Schild H, Radsak MP. Host-derived CD8? dendritic cells protect against acute graft-versus-host disease after experimental allogeneic bone marrow transplantation. Biol Blood Marrow Transplant. 2014 Nov; 20(11):1696-704. PMID: 25132527

Bosmann M, Ward PA. Protein-based therapies for acute lung injury: targeting neutrophil extracellular traps. Expert Opin Ther Targets. 2014 Jun; 18(6):703-14. PMID: 24670033; PMCID: PMC4123211; DOI: 10.1517/14728222.2014.902938;

Bosmann M, Strobl B, Kichler N, Rigler D, Grailer JJ, Pache F, Murray PJ, Müller M, Ward PA. Tyrosine kinase 2 promotes sepsis-associated lethality by facilitating production of interleukin-27. J Leukoc Biol. 2014 Jul; 96(1):123-31. PMID: 24604832; PMCID: PMC4056273; DOI: 10.1189/jlb.3A1013-541R;

Prüfer S, Weber M, Stein P, Bosmann M, Stassen M, Kreft A, Schild H, Radsak MP. Oxidative burst and neutrophil elastase contribute to clearance of Aspergillus fumigatus pneumonia in mice. Immunobiology. 2014 Feb; 219(2):87-96. PMID: 24054721

Bosmann M, Grailer JJ, Ruemmler R, Russkamp NF, Zetoune FS, Sarma JV, Standiford TJ, Ward PA. Extracellular histones are essential effectors of C5aR- and C5L2-mediated tissue damage and inflammation in acute lung injury. FASEB J. 2013 Dec; 27(12):5010-21. PMID: 23982144; PMCID: PMC3834784; DOI: 10.1096/fj.13-236380;

Bosmann M, Ward PA. Modulation of inflammation by interleukin-27. J Leukoc Biol. 2013 Dec; 94(6):1159-65. PMID: 23904441; PMCID: PMC3828601; DOI: 10.1189/jlb.0213107;

Bosmann M, Haggadone MD, Zetoune FS, Sarma JV, Ward PA. The interaction between C5a and both C5aR and C5L2 receptors is required for production of G-CSF during acute inflammation. Eur J Immunol. 2013 Jul; 43(7):1907-13. PMID: 23575697; PMCID: PMC3795516; DOI: 10.1002/eji.201243075;

Bosmann M, Grailer JJ, Russkamp NF, Ruemmler R, Zetoune FS, Sarma JV, Ward PA. CD11c+ alveolar macrophages are a source of IL-23 during lipopolysaccharide-induced acute lung injury. Shock. 2013 May; 39(5):447-52. PMID: 23481504; PMCID: PMC3648809; DOI: 10.1097/SHK.0b013e31828f9c92;

Bosmann M, Meta F, Ruemmler R, Haggadone MD, Sarma JV, Zetoune FS, Ward PA. Regulation of IL-17 family members by adrenal hormones during experimental sepsis in mice. Am J Pathol. 2013 Apr; 182(4):1124-30. PMID: 23499051; PMCID: PMC3620417; DOI: 10.1016/j.ajpath.2013.01.005;

Grailer JJ, Bosmann M, Ward PA. Regulatory effects of C5a on IL-17A, IL-17F, and IL-23. Front Immunol. 2012; 3:387. PMID: 23316190; PMCID: PMC3540403; DOI: 10.3389/fimmu.2012.00387;

Bosmann M, Ward PA. The inflammatory response in sepsis. Trends Immunol. 2013 Mar; 34(3):129-36. PMID: 23036432; PMCID: PMC3543471; DOI: 10.1016/j.it.2012.09.004;

Bosmann M, Russkamp NF, Ward PA. Fingerprinting of the TLR4-induced acute inflammatory response. Exp Mol Pathol. 2012 Dec; 93(3):319-23. PMID: 22981705; PMCID: PMC3518574; DOI: 10.1016/j.yexmp.2012.08.006;

Ward PA, Bosmann M. A historical perspective on sepsis. Am J Pathol. 2012 Jul; 181(1):2-7. PMID: 22642906; PMCID: PMC3388164; DOI: 10.1016/j.ajpath.2012.05.003;

Bosmann M, Ward PA. Therapeutic potential of targeting IL-17 and IL-23 in sepsis. Clin Transl Med. 2012 Apr 27; 1(1):4. PMID: 23369364; PMCID: PMC3552565; DOI: 10.1186/2001-1326-1-4;

Bosmann M, Haggadone MD, Hemmila MR, Zetoune FS, Sarma JV, Ward PA. Complement activation product C5a is a selective suppressor of TLR4-induced, but not TLR3-induced, production of IL-27(p28) from macrophages. J Immunol. 2012 May 15; 188(10):5086-93. PMID: 22491257; PMCID: PMC3345104; DOI: 10.4049/jimmunol.1102914;

Bosmann M, Grailer JJ, Zhu K, Matthay MA, Sarma JV, Zetoune FS, Ward PA. Anti-inflammatory effects of ß2 adrenergic receptor agonists in experimental acute lung injury. FASEB J. 2012 May; 26(5):2137-44. PMID: 22318967; PMCID: PMC3336792; DOI: 10.1096/fj.11-201640;

Bosmann M, Ward PA. Role of C3, C5 and anaphylatoxin receptors in acute lung injury and in sepsis. Adv Exp Med Biol. 2012; 946:147-59. PMID: 21948367; PMCID: PMC3372066; DOI: 10.1007/978-1-4614-0106-3_9;

Bosmann M, Sarma JV, Atefi G, Zetoune FS, Ward PA. Evidence for anti-inflammatory effects of C5a on the innate IL-17A/IL-23 axis. FASEB J. 2012 Apr; 26(4):1640-51. PMID: 22202675; PMCID: PMC3316904; DOI: 10.1096/fj.11-199216;

Bosmann M, Russkamp NF, Patel VR, Zetoune FS, Sarma JV, Ward PA. The outcome of polymicrobial sepsis is independent of T and B cells. Shock. 2011 Oct; 36(4):396-401. PMID: 21701414; PMCID: PMC3175304; DOI: 10.1097/SHK.0b013e3182295f5f;

Bosmann M, Patel VR, Russkamp NF, Pache F, Zetoune FS, Sarma JV, Ward PA. MyD88-dependent production of IL-17F is modulated by the anaphylatoxin C5a via the Akt signaling pathway. FASEB J. 2011 Dec; 25(12):4222-32. PMID: 21859896; PMCID: PMC3236631; DOI: 10.1096/fj.11-191205;

Atefi G, Zetoune FS, Herron TJ, Jalife J, Bosmann M, Al-Aref R, Sarma JV, Ward PA. Complement dependency of cardiomyocyte release of mediators during sepsis. FASEB J. 2011 Jul; 25(7):2500-8. PMID: 21478262; PMCID: PMC3114524; DOI: 10.1096/fj.11-183236;

Bosmann M, Kössler J, Stolz H, Walter U, Knop S, Steigerwald U. Detection of serum free light chains: the problem with antigen excess. Clin Chem Lab Med. 2010 Oct; 48(10):1419-22. PMID: 20626301

Bosmann M, Schreiner O, Galle PR. Coexistence of Cullen's and Grey Turner's signs in acute pancreatitis. Am J Med. 2009 Apr; 122(4):333-4. PMID: 19332225

Bosmann M, Schwarting A. [Non-invasive monitoring of fluid balance]. Dtsch Med Wochenschr. 2009 Feb; 134(9):421-4. PMID: 19224429

Hofstetter C, Flondor M, Boost KA, Koehler P, Bosmann M, Pfeilschifter J, Zwissler B, Mühl H. A brief exposure to isoflurane (50 s) significantly impacts on plasma cytokine levels in endotoxemic rats. Int Immunopharmacol. 2005 Sep; 5(10):1519-22. PMID: 16023603

Nascimbeni M, Mizukoshi E, Bosmann M, Major ME, Mihalik K, Rice CM, Feinstone SM, Rehermann B. Kinetics of CD4+ and CD8+ memory T-cell responses during hepatitis C virus rechallenge of previously recovered chimpanzees. J Virol. 2003 Apr; 77(8):4781-93. PMID: 12663785

Paulukat J, Bosmann M, Nold M, Garkisch S, Kämpfer H, Frank S, Raedle J, Zeuzem S, Pfeilschifter J, Mühl H. Expression and release of IL-18 binding protein in response to IFN-gamma. J Immunol. 2001 Dec 15; 167(12):7038-43. PMID: 11739524

Mühl H, Chang JH, Huwiler A, Bosmann M, Paulukat J, Ninic R, Nold M, Hellmuth M, Pfeilschifter J. Nitric oxide augments release of chemokines from monocytic U937 cells: modulation by anti-inflammatory pathways. Free Radic Biol Med. 2000 Nov 15; 29(10):969-80. PMID: 11084285

Mühl H, Kämpfer H, Bosmann M, Frank S, Radeke H, Pfeilschifter J. Interferon-gamma mediates gene expression of IL-18 binding protein in nonleukocytic cells. Biochem Biophys Res Commun. 2000 Jan 27; 267(3):960-3. PMID: 10673399

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 77 publications over 20 distinct years, with a maximum of 8 publications in 2020 and 2022