Lee J. Quinton, PhD
Adjunct Associate Professor
Boston University Chobanian & Avedisian School of Medicine
Medicine
Pulmonary, Allergy, Sleep & Critical Care Medicine

PhD, Louisiana State University
BS, University of Southern Mississippi



My expertise lies in the areas of the biology of acute pulmonary inflammation and the innate immune response to microorganisms in the lung.

Center Faculty Member
Boston University Chobanian & Avedisian School of Medicine
Pulmonary Center


Graduate Faculty (Primary Mentor of Grad Students)
Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences




Liver-Dependent Lung Remodeling and Pneumonia Susceptibility During Endotoxemia
06/01/2021 - 06/30/2022 (Key Person / Mentor)
NIH/National Heart, Lung, and Blood Institute
5F31HL154615-02

Inducible epithelial resilience during pneumonia
07/01/2017 - 06/30/2022 (PI)
NIH/National Heart, Lung, and Blood Institute
5R01HL111449-09

Liver-derived protection during pneumonia and sepsis
04/01/2017 - 01/31/2022 (PI)
NIH/National Institute of General Medical Sciences
5R01GM120060-04

The role of Lox-1 during pneumonia
09/01/2019 - 08/31/2021 (Key Person / Mentor)
PI: Filiz Korkmaz, PhD
NIH/National Heart, Lung, and Blood Institute
5F32HL147461-02

The Biology of LIF During Pneumonia
06/01/2016 - 06/30/2017 (PI)
NIH/National Heart, Lung, and Blood Institute
4R01HL111449-05

The Biology of LIF During Pneumonia
08/15/2012 - 05/31/2016 (PI)
NIH/National Heart, Lung, and Blood Institute
5R01HL111449-04

Distinct Roles of LIF and OSM During Pneumonia
07/01/2014 - 06/30/2015 (Key Person / Mentor)
PI: Katrina E. Traber, MD, PhD
NIH/National Heart, Lung, and Blood Institute
1F32HL120551-01A1

Lung-Liver Axis During Pneumonia
09/01/2010 - 06/30/2014 (PI)
NIH/National Heart, Lung, and Blood Institute
5R00HL092956-05



Title


Yr Title Project-Sub Proj Pubs
2024 LOX-1 as a protective countermeasure in response to lung infection 5R01HL165718-02
2023 LOX-1 as a protective countermeasure in response to lung infection 1R01HL165718-01A1
2022 LOX-1 as a protective countermeasure in response to lung infection 1R56HL165718-01
2022 2022 Biology of Acute Respiratory Infection GRC / GRS 1R13AI167451-01
2020 Liver-derived protection during pneumonia and sepsis 5R01GM120060-04 10
2020 Inducible epithelial resilience during pneumonia 5R01HL111449-09 20
2019 Liver-derived protection during pneumonia and sepsis 5R01GM120060-03 10
2019 Inducible epithelial resilience during pneumonia 5R01HL111449-08 20
2018 Liver-derived protection during pneumonia and sepsis 5R01GM120060-02 10
2018 Inducible epithelial resilience during pneumonia 5R01HL111449-07 20
Showing 10 of 22 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Korkmaz FT, Quinton LJ. Extra-pulmonary control of respiratory defense. Cell Immunol. 2024; 401-402:104841.View Related Profiles. PMID: 38878619
     
  2. Etesami NS, Barker KA, Shenoy AT, De Ana CL, Arafa EI, Grifno GN, Matschulat AM, Vannini ME, Pihl RMF, Breen MP, Soucy AM, Goltry WN, Ha CT, Betsuyaku H, Browning JL, Varelas X, Traber KE, Jones MR, Quinton LJ, Maglione PJ, Nia HT, Belkina AC, Mizgerd JP. B cells in the pneumococcus-infected lung are heterogeneous and require CD4+ T cell help including CD40L to become resident memory B cells. Front Immunol. 2024; 15:1382638.View Related Profiles. PMID: 38715601; PMCID: PMC11074383; DOI: 10.3389/fimmu.2024.1382638;
     
  3. Gao KM, Chiang K, Jiang Z, Korkmaz FT, Janardhan HP, Trivedi CM, Quinton LJ, Gingras S, Fitzgerald KA, Marshak-Rothstein A. Endothelial cell expression of a STING gain-of-function mutation initiates pulmonary lymphocytic infiltration. Cell Rep. 2024 Apr 23; 43(4):114114.View Related Profiles. PMID: 38625791; PMCID: PMC11108094; DOI: 10.1016/j.celrep.2024.114114;
     
  4. Lyon De Ana C, Shenoy AT, Barker KA, Arafa EI, Etesami NS, Korkmaz FT, Soucy AM, Breen MP, Martin IMC, Tilton BR, Devarajan P, Crossland NA, Pihl RMF, Goltry WN, Belkina AC, Jones MR, Quinton LJ, Mizgerd JP. GL7 ligand expression defines a novel subset of CD4+ TRM cells in lungs recovered from pneumococcus. Mucosal Immunol. 2023 Oct; 16(5):699-710.View Related Profiles. PMID: 37604254; PMCID: PMC10591822; DOI: 10.1016/j.mucimm.2023.07.004;
     
  5. Gao KM, Chiang K, Korkmaz FT, Janardhan HP, Trivedi CM, Quinton LJ, Gingras S, Fitzgerald KA, Marshak-Rothstein A. Expression of a STING Gain-of-function Mutation in Endothelial Cells Initiates Lymphocytic Infiltration of the Lungs. bioRxiv. 2023 Jul 27.View Related Profiles. PMID: 37547024; PMCID: PMC10402179; DOI: 10.1101/2023.07.27.550897;
     
  6. Korkmaz FT, Shenoy AT, Symer EM, Baird LA, Odom CV, Arafa EI, Dimbo EL, Na E, Molina-Arocho W, Brudner M, Standiford TJ, Mehta JL, Sawamura T, Jones MR, Mizgerd JP, Traber KE, Quinton LJ. Lectin-like oxidized low-density lipoprotein receptor 1 attenuates pneumonia-induced lung injury. JCI Insight. 2022 Dec 08; 7(23).View Related Profiles. PMID: 36264633; PMCID: PMC9746901; DOI: 10.1172/jci.insight.149955;
     
  7. Sharma A, Noon JB, Kontodimas K, Garo LP, Platten J, Quinton LJ, Urban JF, Reinhardt C, Bosmann M. IL-27 Enhances ?d T Cell-Mediated Innate Resistance to Primary Hookworm Infection in the Lungs. J Immunol. 2022 Apr 15; 208(8):2008-2018.View Related Profiles. PMID: 35354611; PMCID: PMC9012701; DOI: 10.4049/jimmunol.2000945;
     
  8. Arafa EI, Shenoy AT, Barker KA, Etesami NS, Martin IM, Lyon De Ana C, Na E, Odom CV, Goltry WN, Korkmaz FT, Wooten AK, Belkina AC, Guillon A, Forsberg EC, Jones MR, Quinton LJ, Mizgerd JP. Recruitment and training of alveolar macrophages after pneumococcal pneumonia. JCI Insight. 2022 Mar 08; 7(5).View Related Profiles. PMID: 35133985; PMCID: PMC8983128; DOI: 10.1172/jci.insight.150239;
     
  9. Na E, Allen E, Baird LA, Odom CV, Korkmaz FT, Shenoy AT, Matschulat AM, Jones MR, Kotton DN, Mizgerd JP, Varelas X, Traber KE, Quinton LJ. Epithelial LIF signaling limits apoptosis and lung injury during bacterial pneumonia. Am J Physiol Lung Cell Mol Physiol. 2022 Apr 01; 322(4):L550-L563.View Related Profiles. PMID: 35137631; PMCID: PMC8957336; DOI: 10.1152/ajplung.00325.2021;
     
  10. Sanders NL, Martin IMC, Sharma A, Jones MR, Quinton LJ, Bosmann M, Mizgerd JP. Neutrophil Extracellular Traps as an Exacerbating Factor in Bacterial Pneumonia. Infect Immun. 2022 03 17; 90(3):e0049121.View Related Profiles. PMID: 35130455; PMCID: PMC8929384; DOI: 10.1128/iai.00491-21;
     
Showing 10 of 66 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 66 publications over 23 distinct years, with a maximum of 6 publications in 2012 and 2017

YearPublications
20022
20033
20041
20055
20062
20073
20081
20093
20101
20113
20126
20131
20144
20153
20161
20176
20182
20193
20202
20214
20225
20232
20243

In addition to these self-described keywords below, a list of MeSH based concepts is available here.

cytokines
inflammation
pneumonia
pulmonary

Available to Mentor as: (Review Mentor Role Definitions):
  • Advisor
  • Career Mentor
  • Co-Mentor or Peer Mentor
  • Education Mentor
  • Project Mentor
  • Research / Scholarly Mentor
Contact for Mentoring:

72 E. Concord St Housman (R)
Boston MA 02118
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