Katrina E. Traber, MD, PhD
Assistant Professor
Boston University Chobanian & Avedisian School of Medicine
Medicine
Pulmonary, Allergy, Sleep & Critical Care Medicine

MD, New York University School of Medicine
PhD, New York University School of Medicine
MS, New York University School of Medicine
BA, Wesleyan University

Pronouns: she/her/hers



The long-term goal of the Traber Lab is to identify and develop new strategies to treat severe neutrophil-based sequelae of pneumonia such as ARDS and sepsis. To achieve this goal, we use in vivo and in vitro models of pneumonia to investigate mechanisms of neutrophil dysfunction in acute lung infections. Currently, we have been using two broad approaches to understand neutrophil biology. First, we are examining modulation of the neutrophil transcriptome during neutrophil migration from circulation to the alveolar space. Second, we are investigating how Oncostatin M (OSM), an IL-6 family cytokine produced by neutrophils in many acute and chronic inflammatory settings, including pneumonia, ARDS and sepsis potentiates neutrophil migration to the alveoli during pneumonia.

If you are interested in joining our research group, please contact Dr. Traber at katraber@bu.edu.

Member
Boston University
Pulmonary Center


Member
Boston University
Evans Center for Interdisciplinary Biomedical Research




Transcriptional Regulation of Migrating Neutrophils during Pneumonia
07/01/2021 - 06/30/2026 (PI)
NIH/National Heart, Lung, and Blood Institute
5R01HL158732-04

The Role of Oncostatin-M in Pneumonia
09/01/2016 - 09/30/2021 (PI)
NIH/National Heart, Lung, and Blood Institute
5K08HL130582-05

Distinct Roles of LIF and OSM During Pneumonia
07/01/2014 - 06/30/2015 (PI)
NIH/National Heart, Lung, and Blood Institute
1F32HL120551-01A1



Title


Yr Title Project-Sub Proj Pubs
2024 Transcriptional Regulation of Migrating Neutrophils during Pneumonia 5R01HL158732-04
2023 Transcriptional Regulation of Migrating Neutrophils during Pneumonia 5R01HL158732-03
2022 Transcriptional Regulation of Migrating Neutrophils during Pneumonia 5R01HL158732-02
2021 Transcriptional Regulation of Migrating Neutrophils during Pneumonia 1R01HL158732-01
2020 The Role of Oncostatin-M in Pneumonia 5K08HL130582-05 3
2019 The Role of Oncostatin-M in Pneumonia 5K08HL130582-04 3
2018 The Role of Oncostatin-M in Pneumonia 5K08HL130582-03 3
2017 The Role of Oncostatin-M in Pneumonia 5K08HL130582-02 3
2016 The Role of Oncostatin-M in Pneumonia 1K08HL130582-01A1 3
2014 Distinct roles of LIF and OSM during pneumonia 1F32HL120551-01A1 1

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Auld SC, Sheshadri A, Alexander-Brett J, Aschner Y, Barczak AK, Basil MC, Cohen KA, Dela Cruz C, McGroder C, Restrepo MI, Ridge KM, Schnapp LM, Traber K, Wunderink RG, Zhang D, Ziady A, Attia EF, Carter J, Chalmers JD, Crothers K, Feldman C, Jones BE, Kaminski N, Keane J, Lewinsohn D, Metersky M, Mizgerd JP, Morris A, Ramirez J, Samarasinghe AE, Staitieh BS, Stek C, Sun J, Evans SE. Postinfectious Pulmonary Complications: Establishing Research Priorities to Advance the Field: An Official American Thoracic Society Workshop Report. Ann Am Thorac Soc. 2024 Sep; 21(9):1219-1237.View Related Profiles. PMID: 39051991
     
  2. Etesami NS, Barker KA, Shenoy AT, De Ana CL, Arafa EI, Grifno GN, Matschulat AM, Vannini ME, Pihl RMF, Breen MP, Soucy AM, Goltry WN, Ha CT, Betsuyaku H, Browning JL, Varelas X, Traber KE, Jones MR, Quinton LJ, Maglione PJ, Nia HT, Belkina AC, Mizgerd JP. B cells in the pneumococcus-infected lung are heterogeneous and require CD4+ T cell help including CD40L to become resident memory B cells. Front Immunol. 2024; 15:1382638.View Related Profiles. PMID: 38715601; PMCID: PMC11074383; DOI: 10.3389/fimmu.2024.1382638;
     
  3. Banerji R, Grifno GN, Shi L, Smolen D, LeBourdais R, Muhvich J, Eberman C, Hiller BE, Lee J, Regan K, Zheng S, Zhang S, Jiang J, Raslan AA, Breda JC, Pihl R, Traber K, Mazzilli S, Ligresti G, Mizgerd JP, Suki B, Nia HT. Crystal ribcage: a platform for probing real-time lung function at cellular resolution. Nat Methods. 2023 Nov; 20(11):1790-1801.View Related Profiles. PMID: 37710017; PMCID: PMC10860663; DOI: 10.1038/s41592-023-02004-9;
     
  4. Korkmaz FT, Traber KE. Innate immune responses in pneumonia. Pneumonia (Nathan). 2023 Feb 25; 15(1):4.View Related Profiles. PMID: 36829255; PMCID: PMC9957695; DOI: 10.1186/s41479-023-00106-8;
     
  5. Korkmaz FT, Shenoy AT, Symer EM, Baird LA, Odom CV, Arafa EI, Dimbo EL, Na E, Molina-Arocho W, Brudner M, Standiford TJ, Mehta JL, Sawamura T, Jones MR, Mizgerd JP, Traber KE, Quinton LJ. Lectin-like oxidized low-density lipoprotein receptor 1 attenuates pneumonia-induced lung injury. JCI Insight. 2022 Dec 08; 7(23).View Related Profiles. PMID: 36264633; PMCID: PMC9746901; DOI: 10.1172/jci.insight.149955;
     
  6. Na E, Allen E, Baird LA, Odom CV, Korkmaz FT, Shenoy AT, Matschulat AM, Jones MR, Kotton DN, Mizgerd JP, Varelas X, Traber KE, Quinton LJ. Epithelial LIF signaling limits apoptosis and lung injury during bacterial pneumonia. Am J Physiol Lung Cell Mol Physiol. 2022 Apr 01; 322(4):L550-L563.View Related Profiles. PMID: 35137631; PMCID: PMC8957336; DOI: 10.1152/ajplung.00325.2021;
     
  7. Traber KE, Center DM. Toward a More Precise Solution to Asthma Therapy. Am J Respir Cell Mol Biol. 2021 09; 65(3):241-242.View Related Profiles. PMID: 34153196; PMCID: PMC8485991; DOI: 10.1165/rcmb.2021-0227ED;
     
  8. Odom CV, Kim Y, Burgess CL, Baird LA, Korkmaz FT, Na E, Shenoy AT, Arafa EI, Lam TT, Jones MR, Mizgerd JP, Traber KE, Quinton LJ. Liver-Dependent Lung Remodeling during Systemic Inflammation Shapes Responses to Secondary Infection. J Immunol. 2021 10 01; 207(7):1891-1902.View Related Profiles. PMID: 34470857; PMCID: PMC8631467; DOI: 10.4049/jimmunol.2100254;
     
  9. Traber KE, Dimbo EL, Shenoy AT, Symer EM, Allen E, Mizgerd JP, Quinton LJ. Neutrophil-Derived Oncostatin M Triggers Diverse Signaling Pathways during Pneumonia. Infect Immun. 2021 03 17; 89(4).View Related Profiles. PMID: 33526570; PMCID: PMC8090961; DOI: 10.1128/IAI.00655-20;
     
  10. Guillon A, Arafa EI, Barker KA, Belkina AC, Martin I, Shenoy AT, Wooten AK, Lyon De Ana C, Dai A, Labadorf A, Hernandez Escalante J, Dooms H, Blasco H, Traber KE, Jones MR, Quinton LJ, Mizgerd JP. Pneumonia recovery reprograms the alveolar macrophage pool. JCI Insight. 2020 02 27; 5(4).View Related Profiles. PMID: 31990682; PMCID: PMC7101156; DOI: 10.1172/jci.insight.133042;
     
Showing 10 of 20 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 20 publications over 11 distinct years, with a maximum of 3 publications in 2015 and 2021

YearPublications
20051
20061
20081
20153
20172
20192
20201
20213
20222
20232
20242

In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Pneumonia
Innate Immunity
Neutrophil
Oncostatin M
Pulmonary Epithelium
Lower respiratory tract infection
Cytokines
Chemokines
STAT3 Transcription Factor
IL-6 family cytokines
Acute lung injury
Macrophage
ARDS, Human

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72 E. Concord St Housman (R)
Boston MA 02118
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