Finn Hawkins, MBBCh
Associate Professor
Boston University Chobanian & Avedisian School of Medicine
Medicine
Pulmonary, Allergy, Sleep & Critical Care Medicine

MBBCh, National University of Ireland



Dr. Hawkins is a Principal Investigator (P.I.) in the Center for Regenerative Medicine and The Pulmonary Center. His research focus is studying human lung development and disease using human induced pluripotent stem cells (iPSCs). Dr. Hawkins is currently using iPSC technology to study airway biology with a focus on Cystic Fibrosis.

Diversity, Equity, Inclusion and Accessibility

Pulmonary Combined Clinical and Research Conference we established in 2022 a mechanism for trainees to invite an outside speaker annually with a goal of increasing the diversity of our invited experts.
2022-2023 Participate in our diversity equity and inclusion workshops, every two months, as part of our Pulmonary Combined Clinical and Research Conference (led by Dr. Klings).
2021 Helped establish a small library in the Center for Regenerative Medicine to improve education and understanding of racism and disparities within medicine and science.

Member
Boston University
Pulmonary Center


Member
Boston University
Center for Regenerative Medicine


Graduate Faculty (Primary Mentor of Grad Students)
Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences




Genotype to Phenotype Assessment of Primary Ciliary Dyskinesia Variants in Under Studied Populations
07/01/2024 - 06/30/2026 (Key Person / Mentor)
PI: Daniel Wallman, MD
American Lung Association


Regenerating Airway Epithelium with Basal Cells Derived from Human iPSCs
02/01/2021 - 01/31/2025 (PI)
Cystic Fibrosis Foundation


iPSC-Derived Airway Basal Cells to Model Human Airway Development and Disease
09/01/2018 - 08/31/2024 (PI)
NIH/National Heart, Lung, and Blood Institute
5R01HL139799-05

Map the human airway basal cell niche and the role that FGFR2 plays within it
09/01/2023 - 06/30/2024 (Key Person / Mentor)
PI: Daniel Wallman, MD
NIH/National Heart, Lung, and Blood Institute
1F32HL170761-01

Investigating the Role of NKX2-1 in Early Human Lung Development Using an Induced Pluripotent Stem Cell (iPSC) Model
09/01/2022 - 05/31/2024 (Key Person / Mentor)
PI: Taylor Matte, PhD
NIH/National Heart, Lung, and Blood Institute
5F31HL165922-02

Epithelial stem/progenitor cells as repair agents in diffuse alveolar damage
09/21/2016 - 05/31/2024 (Co-Investigator)
PI: Darrell Nelson Kotton, MD
The Regents of the University of California, San Francisco NIH NHLBI
5U01HL134766-07

De-Novo Generation of Pulmonary ionocytes from Human Pluripotent Stem Cells
11/01/2020 - 10/31/2022 (Multi-PI)
PI: Finn Hawkins, MBBCh
Cystic Fibrosis Foundation


iPSC-Derived Small Airway Epithelial Cells as a Novel Model for Cystic Fibrosis
07/01/2020 - 06/30/2022 (Key Person / Mentor)
PI: Andrew Berical, MD
Cystic Fibrosis Foundation


Generation of functional lung stem cells from human iPSCs
07/01/2019 - 06/30/2022 (Multi-PI)
PI: Finn Hawkins, MBBCh
NIH/National Heart, Lung, and Blood Institute
5U01HL148692-02

Refining stage-specific patterning to efficiently generate basal cells from iPSCs
07/01/2019 - 07/31/2021 (PI)
Cystic Fibrosis Foundation


Showing 10 of 14 results. Show All Results


Title


Yr Title Project-Sub Proj Pubs
2024 Mapping genotype to phenotype in PCD using iPSCs 1P01HL170952-01-7289
2022 iPSC-Derived Airway Basal Cells to Model Human Airway Development and Disease 5R01HL139799-05
2021 iPSC-Derived Airway Basal Cells to Model Human Airway Development and Disease 5R01HL139799-04 3
2020 Generation of functional lung stem cells from human iPSCs 5U01HL148692-02 1
2020 iPSC-Derived Airway Basal Cells to Model Human Airway Development and Disease 5R01HL139799-03 3
2019 Generation of functional lung stem cells from human iPSCs 1U01HL148692-01 1
2019 iPSC-Derived Airway Basal Cells to Model Human Airway Development and Disease 5R01HL139799-02 3
2018 iPSC-Derived Airway Basal Cells to Model Human Airway Development and Disease 1R01HL139799-01A1 3

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Berical AC, Kiyokawa H, Beermann ML, Wallman D, Cherfane G, Dunphy V, Pan J, Tilston-Lunel A, Varelas X, Horani A, Brody SL, Kotton DN, Hawkins FJ. Airway Disease Modeling with Gene-edited Human Basal Cell Transplantation. Am J Respir Crit Care Med. 2024 Nov 08.View Related Profiles. PMID: 39514838
     
  2. Ma L, Thapa BR, Le Suer JA, Tilston-Lünel A, Herriges MJ, Wang F, Bawa PS, Varelas X, Hawkins FJ, Kotton DN. Life-long functional regeneration of in vivo airway epithelium by the engraftment of airway basal stem cells. Nat Protoc. 2024 Nov 05.View Related Profiles. PMID: 39501108
     
  3. Koenitzer JR, Gupta DK, Twan WK, Xu H, Hadas N, Hawkins FJ, Beermann ML, Penny GM, Wamsley NT, Berical A, Major MB, Dutcher SK, Brody SL, Horani A. Transcriptional analysis of primary ciliary dyskinesia airway cells reveals a dedicated cilia glutathione pathway. JCI Insight. 2024 Jul 23; 9(17).View Related Profiles. PMID: 39042459; PMCID: PMC11385084; DOI: 10.1172/jci.insight.180198;
     
  4. Brody SL, Pan J, Huang T, Xu J, Xu H, Koenitizer J, Brennan SK, Nanjundappa R, Saba TG, Berical A, Hawkins FJ, Wang X, Zhang R, Mahjoub MR, Horani A, Dutcher SK. Loss of an extensive ciliary connectome induces proteostasis and cell fate switching in a severe motile ciliopathy. bioRxiv. 2024 Mar 21.View Related Profiles. PMID: 38562900; PMCID: PMC10983967; DOI: 10.1101/2024.03.20.585965;
     
  5. Dagher R, Moldobaeva A, Gubbins E, Clark S, Madel Alfajaro M, Wilen CB, Hawkins F, Qu X, Chien Chiang C, Li Y, Clarke L, Ikeda Y, Brown C, Kolbeck R, Ma Q, Rojas M, Koff JL, Ghaedi M. Human iPSC-Based Model of COPD to Investigate Disease Mechanisms, Predict SARS-COV-2 Outcome, and Test Preventive Immunotherapy. Stem Cells. 2024 Mar 14; 42(3):230-250. PMID: 38183264
     
  6. Shankar DA, Hawkins F, Alysandratos KD, Wilson KC, Walkey AJ, Bosch NA, Law AC. Uptake of Antifibrotics for Patients with Idiopathic Pulmonary Fibrosis: 2016-2022. Ann Am Thorac Soc. 2024 Jan; 21(1):170-173.View Related Profiles. PMID: 37879035; PMCID: PMC10867915; DOI: 10.1513/AnnalsATS.202308-697RL;
     
  7. Lee RE, Mascenik TM, Major SC, Galiger JR, Bulik-Sullivan E, Siesser PF, Lewis CA, Bear JE, Le Suer JA, Hawkins FJ, Pickles RJ, Randell SH. Viral airway injury promotes cell engraftment in an in vitro model of cystic fibrosis cell therapy. Am J Physiol Lung Cell Mol Physiol. 2024 Mar 01; 326(3):L226-L238. PMID: 38150545; PMCID: PMC11280688; DOI: 10.1152/ajplung.00421.2022;
     
  8. Miura A, Sarmah H, Tanaka J, Hwang Y, Sawada A, Shimamura Y, Otoshi T, Kondo Y, Fang Y, Shimizu D, Ninish Z, Suer JL, Dubois NC, Davis J, Toyooka S, Wu J, Que J, Hawkins FJ, Lin CS, Mori M. Conditional blastocyst complementation of a defective Foxa2 lineage efficiently promotes the generation of the whole lung. Elife. 2023 Oct 20; 12. PMID: 37861292; PMCID: PMC10642968; DOI: 10.7554/eLife.86105;
     
  9. Ma L, Thapa BR, Le Suer JA, Tilston-Lünel A, Herriges MJ, Berical A, Beermann ML, Wang F, Bawa PS, Kohn A, Ysasi AB, Kiyokawa H, Matte TM, Randell SH, Varelas X, Hawkins FJ, Kotton DN. Airway stem cell reconstitution by the transplantation of primary or pluripotent stem cell-derived basal cells. Cell Stem Cell. 2023 Sep 07; 30(9):1199-1216.e7.View Related Profiles. PMID: 37625411; PMCID: PMC10528754; DOI: 10.1016/j.stem.2023.07.014;
     
  10. Wang R, Simone-Roach C, Lindstrom-Vautrin J, Wang F, Rollins S, Bawa PS, Lu J, Tang Y, Beermann ML, Schlaeger T, Mahoney J, Rowe SM, Hawkins FJ, Kotton DN. De Novo Generation of Pulmonary Ionocytes from Normal and Cystic Fibrosis Human Induced Pluripotent Stem Cells. Am J Respir Crit Care Med. 2023 May 01; 207(9):1249-1253.View Related Profiles. PMID: 36857488; PMCID: PMC10161739; DOI: 10.1164/rccm.202205-1010LE;
     
Showing 10 of 43 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 43 publications over 13 distinct years, with a maximum of 8 publications in 2020

YearPublications
20092
20101
20111
20121
20153
20174
20183
20193
20208
20212
20224
20235
20246


2024 Ignition Awards Aim to Bring BU Science and Tech to Market

The Brink 8/22/2024

BU Researchers See Future Where Lung Disease Is Treatable, and Damaged Lungs Are Regenerated

BU Today 8/31/2023

Human Airway Basal Stem Cells Created from Patients’ Cells

Genetic Engineering & Biotechnology News: 10/27/2020

Patient-specific airway stem cells developed to model lung diseases

The Science Advisory Board 10/26/2020

What Sets Off Deadly Levels of Lung Inflammation in Some COVID-19 Patients?

BU Today 9/8/2020

Chasing a Cure for Lung Disease With Stem Cells: A Conversation With Finn Hawkins

HealthCity 7/2/2019

2019 Evan’s Junior Faculty Merit Award
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