NRT-URoL: A Convergent Training Program on Biological Control08/01/2023 - 07/31/2028 (Multi-PI)
PI:
Ahmad (Mo) Khalil, PhDNational Science FoundationDGE-2244366
Synthetic vascularization and regeneration in engineered tissues09/01/2023 - 08/31/2027 (Multi-PI)
PI:
Ahmad (Mo) Khalil, PhDNIH/National Institute of Biomedical Imaging & Bioengineering1R01EB033821-01
Programmable benchtop bioreactors for scalable eco-evolutionary dynamics of the human microbiome06/10/2022 - 05/31/2027 (PI)
NIH/National Institute of Allergy & Infectious Diseases5R01AI171100-02
ePACE: automation platforms for adaptable and scalable continuous evolution of biomolecules with therapeutic potential07/01/2023 - 03/31/2027 (PI)
NIH/National Institute of Biomedical Imaging & Bioengineering2R01EB027793-05
Schmidt Science Polymath Award12/01/2022 - 10/31/2026 (PI)
The Eric and Wendy Schmidt Fund For Strategic Innovation
Damon Runyon Postdoctoral Fellowship Award10/01/2022 - 09/30/2026 (Key Person / Mentor)
Damon Runyon Cancer Research Foundation
Automated Nanobody Selection Collaboration08/15/2023 - 02/14/2026 (PI)
Merck, Sharp & Dohme LLC
Epigenetically Programmed Biological Materials08/12/2020 - 08/11/2025 (PI)
Department of Defense/ONR
Scalable and automatable nanobody discovery and affinity maturation in yeast07/13/2022 - 07/13/2025 (PI)
FTX Philanthropy, Inc.
Deciphering a new dimension of GPCR biology through the continuous evolution of biased modulators07/01/2022 - 06/30/2025 (Subcontract PI)
University of California, Irvine Keck Foundation
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Design and in vivo comparison of alternative strategies for artificial Zinc Finger (aZnF) based regulatable gene therapies03/04/2022 - 09/03/2024 (Multi-PI)
PI:
Ahmad (Mo) Khalil, PhDNovartis Institutes for BioMedical Research
URoL: Epigenetics 2: Robustness and Adaptability of the Dynamic Epigenome: A Multiscale Approach10/01/2022 - 08/31/2024 (Subcontract PI)
Brandeis University National Science Fdn
Semi-continuous evolution of DNMT3A/L-binding nanobodies for targeted epigenome editing09/01/2021 - 08/31/2024 (PI)
Chroma Medicine, Inc.
Schmidt Futures "Modular Biofilm Reactors to Convert Waste-Based Feedstocks to Vitamin A"03/01/2023 - 08/30/2024 (Multi-PI)
PI:
Ahmad (Mo) Khalil, PhDBioMADE Schmidt Futures
Synthetic Biology and Biotechnology (SB2) Predoctoral Training Program07/01/2019 - 06/30/2024 (Multi-PI)
PI:
Ahmad (Mo) Khalil, PhDNIH/National Institute of General Medical Sciences5T32GM130546-05
Synthetic toolkit for precision gene expression control and signal processing in mammalian cells05/01/2020 - 01/31/2024 (Multi-PI)
PI:
Ahmad (Mo) Khalil, PhDNIH/National Institute of Biomedical Imaging & Bioengineering5R01EB029483-04
Development of synthetic gene feedback circuits to prevent tau aggregation02/01/2020 - 01/31/2024 (Multi-PI)
PI:
Ahmad (Mo) Khalil, PhDBright Focus Foundation
Development of Small-Molecule Regulated Effector Expression in CAR-T Cells07/01/2020 - 07/01/2023 (PI)
Senti Biosciences
ePACE: an automated system for high-throughput, closed-loop control of continuous molecular evolution to enable novel therapeutics05/03/2019 - 06/30/2023 (PI)
NIH/National Institute of Biomedical Imaging & Bioengineering5R01EB027793-04
Automated semi-continuous evolution of therapeutic binding proteins and bioconjugation enzymes06/18/2021 - 06/18/2023 (PI)
Merck, Sharp & Dohme LLC
Deciphering genetic and epigenetic regulation in eukaryotic gene clusters using synthetic genomics01/01/2021 - 02/28/2023 (Key Person / Mentor)
European Molecular Biology Organization
URoL: Epigenetics 2: Robustness and Adaptability of the Dynamic Epigenome: A Multiscale Approach09/01/2019 - 07/31/2022 (Subcontract PI)
University of Michigan National Science FdnEF-1921677
Draper Team Felix Proposal08/27/2018 - 04/21/2022 (Subcontract PI)
Draper Laboratory, Inc. Ntl Intel - IARPA
Collaborative Research: Evolvable Living Computing - Understanding and Quantifying Synthetic Biological Systems' Applicability, Performance, and Limits12/15/2015 - 11/30/2021 (Co-Investigator)
National Science FoundationCCF-1522074
Technologies to Control, Surveil, and Counter Genome-editing Nucleases and Gene Drives05/01/2019 - 09/30/2021 (Subcontract PI)
Massachusetts General Hospital DOD DARPA
The Sodium Channel as a Therapeutic Target for Prevention of Lethal Cardiac Arrhythmias09/01/2020 - 08/31/2021 (Subcontract PI)
The Brigham and Women's Hospital, Inc. Fondation Leducq
Combating antibiotic resistance with synthetic biology technologies09/30/2016 - 08/31/2021 (PI)
NIH/National Institute of Allergy & Infectious Diseases1DP2AI131083-01
Billing Agreement for Charles Jo 07/06/2020 -07/05/202107/06/2020 - 01/31/2021 (Subcontract PI)
The Children's Hospital Corporation NIH NIAID5K08AI130392-04
Collaborative Research: NSF/MCB: Kinetic Control of the Transcription Cycle Revealed by Synthetic Enhancers09/01/2017 - 12/31/2020 (PI)
National Science FoundationMCB-1713855
A low-cost, highly scalable continuous culture system for rapid optimization and precise tuning of gut microbial formulations05/01/2019 - 10/31/2020 (PI)
Bill and Melinda Gates Foundation
Billing Agreement for Shane Wright 09/04/2019 - 08/31/202009/04/2019 - 08/31/2020 (Subcontract PI)
The Brigham and Women's Hospital, Inc. Fondation Leducq
Leverage the eVOLVER framework to enhance the protein design cycle for protein engineering and biocatalysis efforts.11/10/2018 - 05/10/2020 (PI)
Merck, Sharp & Dohme LLC
Khalil Sigilon agreement12/07/2018 - 12/07/2019 (PI)
Sigilon Therapeutics, Inc.
Billing Agreement for James Chuang 09/03/18-09/01/1909/03/2018 - 09/01/2019 (PI)
President & Fellows of Harvard College on behalf of Harvard Medical School
Billing Agreement for James Chuang 09/03/18-09/01/1909/03/2018 - 09/01/2019 (Subcontract PI)
President & Fellows of Harvard College on behalf of Harvard Medical School NIH NIGMS5R01GM120038-02
Surveillance of Passenger Organisms to Record Embarkment01/05/2018 - 07/02/2019 (Subcontract PI)
President & Fellows of Harvard College on behalf of Harvard Medical School DOD DARPA
Detecting antibiotic resistance with rapid RNA sensors04/01/2016 - 03/31/2019 (PI)
The Hartwell Foundation
CAREER: Evolution and Engineering of Cellular Bet-Hedging Devices12/15/2013 - 11/30/2018 (PI)
National Science FoundationMCB-1350949
Advanced genetic control for gene therapy using synthetic biology09/15/2016 - 09/14/2018 (PI)
Department of Defense/DARPA
Billing Agreement for James Chuang06/01/2018 - 09/02/2018 (Subcontract PI)
President & Fellows of Harvard College on behalf of Harvard Medical School NIH NIGMSR01GM120038-01A1
Billing Agreement for James Chuang06/01/2018 - 09/02/2018 (PI)
President & Fellows of Harvard College on behalf of Harvard Medical School
ROBUST: Robust Operation of Bacterial Universes with Synthetic-biology Technologies06/29/2015 - 06/28/2018 (Subcontract PI)
Massachusetts Institute of Technology DOD DARPA
Billing Agreement for James Chuang09/04/2017 - 05/31/2018 (Subcontract PI)
President & Fellows of Harvard College on behalf of Harvard Medical School NIH NIGMS5R01GM032967-34
Sponsorship of the Fourth International Mammalian Synthetic Biology Workshop05/06/2017 - 05/07/2017 (PI)
Pfizer, Inc.
Billing Agreement for James Chuang09/01/2016 - 11/30/2016 (Subcontract PI)
President & Fellows of Harvard College on behalf of Harvard Medical School NIH NIGMS5R01GM032967-33
Development of Inducible Gene Expression System for Cellular Immunotherapy02/26/2016 - 11/04/2016 (Co-Investigator)
PI:
Wilson Wong, PhDLentigen Technology Inc.
Billing Agreement for James Chuang09/01/2015 - 08/31/2016 (Subcontract PI)
President & Fellows of Harvard College on behalf of Harvard Medical School NIH NIGMS5R01GM032967-32
Diagnostic Chip for Rapid Antibiotic Susceptibility Testing Using Reactive Oxygen Species in the Clinical Setting09/04/2013 - 09/03/2015 (PI)
Institut Merieux
Billing Agreement for James Chuang09/01/2014 - 08/31/2015 (PI)
President & Fellows of Harvard College on behalf of Harvard Medical School