Ahmad Khalil, PhD
Associate Professor
Boston University College of Engineering
Dept of Biomedical Engineering

PhD, Massachusetts Institute of Technology
MS, Massachusetts Institute of Technology

Epigenetically Programmed Biological Materials
08/12/2020 - 08/11/2025 (PI)
Department of Defense/ONR

URoL: Epigenetics 2: Robustness and Adaptability of the Dynamic Epigenome: A Multiscale Approach
09/01/2019 - 08/31/2024 (Subcontract PI)
University of Michigan National Science Fdn

Synthetic Biology and Biotechnology (SB2) Predoctoral Training Program
07/01/2019 - 06/30/2024 (Multi-PI)
NIH/National Institute of General Medical Sciences

Synthetic toolkit for precision gene expression control and signal processing in mammalian cells
05/01/2020 - 01/31/2024 (PI)
NIH/National Institute of Biomedical Imaging & Bioengineering

Automated semi-continuous evolution of therapeutic binding proteins and bioconjugation enzymes
06/18/2021 - 06/18/2023 (PI)
Merck, Sharp & Dohme Corp

Semi-continuous evolution of DNMT3A/L-binding nanobodies for targeted epigenome editing
09/01/2021 - 02/28/2023 (PI)
Chroma Medicine, Inc.

Development of synthetic gene feedback circuits to prevent tau aggregation
02/01/2020 - 01/31/2023 (Multi-PI)
Bright Focus Foundation

ePACE: an automated system for high-throughput, closed-loop control of continuous molecular evolution to enable novel therapeutics
05/03/2019 - 01/31/2023 (PI)
NIH/National Institute of Biomedical Imaging & Bioengineering

Development of Small-Molecule Regulated Effector Expression in CAR-T Cells
07/01/2020 - 07/01/2022 (PI)
Senti Biosciences

Draper Team Felix Proposal
08/27/2018 - 04/21/2022 (Subcontract PI)
Draper Laboratory, Inc. Ntl Intel - IARPA

Showing 10 of 36 results. Show All Results


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Sutradhar I, Ching C, Desai D, Suprenant M, Briars E, Heins Z, Khalil AS, Zaman MH. Computational Model To Quantify the Growth of Antibiotic-Resistant Bacteria in Wastewater. mSystems. 2021 Jun 29; 6(3):e0036021.View Related Profiles. PMID: 34100640; PMCID: PMC8579810; DOI: 10.1128/mSystems.00360-21;
  2. Annas GJ, Beisel CL, Clement K, Crisanti A, Francis S, Galardini M, Galizi R, Grünewald J, Immobile G, Khalil AS, Müller R, Pattanayak V, Petri K, Paul L, Pinello L, Simoni A, Taxiarchi C, Joung JK. A Code of Ethics for Gene Drive Research. CRISPR J. 2021 02; 4(1):19-24.View Related Profiles. PMID: 33571044; PMCID: PMC7898401; DOI: 10.1089/crispr.2020.0096;
  3. Qian J, Lu ZX, Mancuso CP, Jhuang HY, Del Carmen Barajas-Ornelas R, Boswell SA, Ramírez-Guadiana FH, Jones V, Sonti A, Sedlack K, Artzi L, Jung G, Arammash M, Pettit ME, Melfi M, Lyon L, Owen SV, Baym M, Khalil AS, Silver PA, Rudner DZ, Springer M. Barcoded microbial system for high-resolution object provenance. Science. 2020 06 05; 368(6495):1135-1140. PMID: 32499444
  4. Chiesa G, Kiriakov S, Khalil AS. Protein assembly systems in natural and synthetic biology. BMC Biol. 2020 03 26; 18(1):35. PMID: 32216777; PMCID: PMC7099826; DOI: 10.1186/s12915-020-0751-4;
  5. Heins ZJ, Mancuso CP, Kiriakov S, Wong BG, Bashor CJ, Khalil AS. Designing Automated, High-throughput, Continuous Cell Growth Experiments Using eVOLVER. J Vis Exp. 2019 05 19; (147). PMID: 31157778; PMCID: PMC6738936; DOI: 10.3791/59652;
  6. Weinstein ZB, Kuru N, Kiriakov S, Palmer AC, Khalil AS, Clemons PA, Zaman MH, Roth FP, Cokol M. Modeling the impact of drug interactions on therapeutic selectivity. Nat Commun. 2018 08 27; 9(1):3452.View Related Profiles. PMID: 30150706; PMCID: PMC6110842; DOI: 10.1038/s41467-018-05954-3;
  7. Wong BG, Mancuso CP, Kiriakov S, Bashor CJ, Khalil AS. Precise, automated control of conditions for high-throughput growth of yeast and bacteria with eVOLVER. Nat Biotechnol. 2018 08; 36(7):614-623. PMID: 29889214; PMCID: PMC6035058; DOI: 10.1038/nbt.4151;
  8. Newby GA, Kiriakov S, Hallacli E, Kayatekin C, Tsvetkov P, Mancuso CP, Bonner JM, Hesse WR, Chakrabortee S, Manogaran AL, Liebman SW, Lindquist S, Khalil AS. A Genetic Tool to Track Protein Aggregates and Control Prion Inheritance. Cell. 2017 Nov 02; 171(4):966-979.e18. PMID: 29056345; PMCID: PMC5675731; DOI: 10.1016/j.cell.2017.09.041;
  9. Mancuso CP, Kiriakov S, Khalil AS. Cellular Advantages to Signaling in a Digital World. Cell Syst. 2016 Aug; 3(2):114-115. PMID: 27559921
  10. Lobritz MA, Belenky P, Porter CB, Gutierrez A, Yang JH, Schwarz EG, Dwyer DJ, Khalil AS, Collins JJ. Antibiotic efficacy is linked to bacterial cellular respiration. Proc Natl Acad Sci U S A. 2015 Jul 07; 112(27):8173-80. PMID: 26100898
Showing 10 of 13 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 13 publications over 9 distinct years, with a maximum of 2 publications in 2015 and 2018 and 2020 and 2021

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610 Commonwealth Ave
Boston MA 02215
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