Michael J. Herriges, PhD
Assistant Professor
Boston University Chobanian & Avedisian School of Medicine
Medicine
Pulmonary, Allergy, Sleep & Critical Care Medicine




Michael Herriges is an Assistant Professor of Medicine at the Chobanian and Avedisian School of Medicine. He obtained his PhD at the University of Pennsylvania. During this time he worked in the lab of Dr. Ed Morrisey studying the role of lncRNAs in pulmonary development and homeostasis. After completing his thesis, Michael did a postdoctoral fellowship in Dr. Darrell Kotton’s lab at Boston University. During this fellowship he developed a system for the differentiation of embryonic stem cells (ESCs) into lung epithelial progenitors known as tip cells. He then engrafted these ESC-derived cells into injured mouse lungs, where they gave rise to engineered cells that were transcriptionally and functionally similar to endogenous alveolar epithelial cells. Having established his own lab in January 2025, Michael now aims to improve cell engraftment techniques and use these methods to study cell-cell interactions and develop cell therapies for pulmonary diseases like pulmonary fibrosis and bronchopulmonary dysplasia.


Pluripotent stem cell-derived cell therapy for lung disease
07/01/2023 - 06/30/2026 (PI)
Parker B. Francis Fellowship Program


Cell-based therapy for lung disease utilizing pluripotent stem cells
09/01/2019 - 08/31/2020 (PI)
NIH/National Heart, Lung, and Blood Institute
1F32HL149263-01

PCTC Administrative Coordinating Center
07/01/2018 - 05/31/2019 (Subcontract PI)
University of Maryland, Baltimore County NIH NHLBI
5U24HL134763-03



Title


Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Kohn A, Herriges MJ, Basak P, Ma L, Thapa BR, Kotton DN, Hawkins FJ. Targeted Pre-Conditioning and Cell Transplantation in the Murine Lower Respiratory Tract. Am J Respir Cell Mol Biol. 2025 Jun 20.View Related Profiles. PMID: 40540686; DOI: 10.1165/rcmb.2024-0597MA;
     
  2. Ma L, Thapa BR, Le Suer JA, Tilston-Lünel A, Herriges MJ, Wang F, Bawa PS, Varelas X, Hawkins FJ, Kotton DN. Author Correction: Life-long functional regeneration of in vivo airway epithelium by the engraftment of airway basal stem cells. Nat Protoc. 2025 Mar 31.View Related Profiles. PMID: 40164751
     
  3. Kohn A, Herriges MJ, Basak P, Ma L, Thapa BR, Kotton DN, Hawkins FJ. Targeted pre-conditioning and cell transplantation in the murine lower respiratory tract. bioRxiv. 2024 Nov 13.View Related Profiles. PMID: 39605510; PMCID: PMC11601482; DOI: 10.1101/2024.11.12.622518;
     
  4. Ma L, Thapa BR, Le Suer JA, Tilston-Lünel A, Herriges MJ, Wang F, Bawa PS, Varelas X, Hawkins FJ, Kotton DN. Life-long functional regeneration of in vivo airway epithelium by the engraftment of airway basal stem cells. Nat Protoc. 2025 Mar; 20(3):810-842.View Related Profiles. PMID: 39501108
     
  5. Yampolskaya M, Herriges MJ, Ikonomou L, Kotton DN, Mehta P. scTOP: physics-inspired order parameters for cellular identification and visualization. Development. 2023 Nov 01; 150(21).View Related Profiles. PMID: 37756586; PMCID: PMC10629677; DOI: 10.1242/dev.201873;
     
  6. Ma L, Thapa BR, Le Suer JA, Tilston-Lünel A, Herriges MJ, Berical A, Beermann ML, Wang F, Bawa PS, Kohn A, Ysasi AB, Kiyokawa H, Matte TM, Randell SH, Varelas X, Hawkins FJ, Kotton DN. Airway stem cell reconstitution by the transplantation of primary or pluripotent stem cell-derived basal cells. Cell Stem Cell. 2023 Sep 07; 30(9):1199-1216.e7.View Related Profiles. PMID: 37625411; PMCID: PMC10528754; DOI: 10.1016/j.stem.2023.07.014;
     
  7. Herriges MJ, Yampolskaya M, Thapa BR, Lindstrom-Vautrin J, Wang F, Huang J, Na CL, Ma L, Montminy MM, Bawa P, Villacorta-Martin C, Mehta P, Kotton DN. Durable alveolar engraftment of PSC-derived lung epithelial cells into immunocompetent mice. Cell Stem Cell. 2023 Sep 07; 30(9):1217-1234.e7.View Related Profiles. PMID: 37625412; PMCID: PMC10529386; DOI: 10.1016/j.stem.2023.07.016;
     
  8. Yampolskaya M, Herriges M, Ikonomou L, Kotton D, Mehta P. scTOP: physics-inspired order parameters for cellular identification and visualization. bioRxiv. 2023 Jan 25.View Related Profiles. PMID: 36747864; PMCID: PMC9900792; DOI: 10.1101/2023.01.25.525581;
     
  9. Wang SW, Herriges MJ, Hurley K, Kotton DN, Klein AM. CoSpar identifies early cell fate biases from single-cell transcriptomic and lineage information. Nat Biotechnol. 2022 Jul; 40(7):1066-1074.View Related Profiles. PMID: 35190690
     
  10. Rankin SA, Steimle JD, Yang XH, Rydeen AB, Agarwal K, Chaturvedi P, Ikegami K, Herriges MJ, Moskowitz IP, Zorn AM. Tbx5 drives Aldh1a2 expression to regulate a RA-Hedgehog-Wnt gene regulatory network coordinating cardiopulmonary development. Elife. 2021 10 13; 10. PMID: 34643182; PMCID: PMC8555986; DOI: 10.7554/eLife.69288;
     
Showing 10 of 20 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 20 publications over 11 distinct years, with a maximum of 4 publications in 2020 and 2023

YearPublications
20131
20142
20161
20171
20191
20204
20211
20221
20234
20242
20252

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2021 ATS International Conference Abstract Scholarship
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